28 results on '"Michelle I. Cardel"'
Search Results
2. The Personalized Nutrition Study (POINTS): evaluation of a genetically informed weight loss approach, a Randomized Clinical Trial
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Christoph Höchsmann, Shengping Yang, José M. Ordovás, James L. Dorling, Catherine M. Champagne, John W. Apolzan, Frank L. Greenway, Michelle I. Cardel, Gary D. Foster, and Corby K. Martin
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Science - Abstract
Abstract Weight loss (WL) differences between isocaloric high-carbohydrate and high-fat diets are generally small; however, individual WL varies within diet groups. Genotype patterns may modify diet effects, with carbohydrate-responsive genotypes losing more weight on high-carbohydrate diets (and vice versa for fat-responsive genotypes). We investigated whether 12-week WL (kg, primary outcome) differs between genotype-concordant and genotype-discordant diets. In this 12-week single-center WL trial, 145 participants with overweight/obesity were identified a priori as fat-responders or carbohydrate-responders based on their combined genotypes at ten genetic variants and randomized to a high-fat (n = 73) or high-carbohydrate diet (n = 72), yielding 4 groups: (1) fat-responders receiving high-fat diet, (2) fat-responders receiving high-carbohydrate diet, (3) carbohydrate-responders receiving high-fat diet, (4) carbohydrate-responders receiving high-carbohydrate diet. Dietitians delivered the WL intervention via 12 weekly diet-specific small group sessions. Outcome assessors were blind to diet assignment and genotype patterns. We included 122 participants (54.4 [SD:13.2] years, BMI 34.9 [SD:5.1] kg/m2, 84% women) in the analyses. Twelve-week WL did not differ between the genotype-concordant (−5.3 kg [SD:1.0]) and genotype-discordant diets (−4.8 kg [SD:1.1]; adjusted difference: −0.6 kg [95% CI: −2.1,0.9], p = 0.50). With the current ability to genotype participants as fat- or carbohydrate-responders, evidence does not support greater WL on genotype-concordant diets. ClinicalTrials identifier: NCT04145466.
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- 2023
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3. A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control
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John W. Apolzan, Jessica Gokee LaRose, Stephen D. Anton, Robbie A. Beyl, Frank L. Greenway, Edmond P. Wickham, Autumn Lanoye, Melissa N. Harris, Corby K. Martin, Tiffany Bullard, Gary D. Foster, and Michelle I. Cardel
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Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background The objective was to test the efficacy of a scalable, virtually delivered, diabetes-tailored weight management program on glycemic control in adults with type 2 diabetes (T2D). Methods This was a single arm, three-site clinical trial. Participants had baseline HbA1c between 7–11% and BMI between 27–50 kg/m2. Primary outcome was change in HbA1c at 24 weeks. Secondary outcomes were changes in body weight, waist circumference, the Diabetes Distress Scale (DDS), quality of life (IWQOL-L), and hunger (VAS). Generalized linear effects models were used for statistical analysis. Results Participants (n = 136) were 56.8 ± 0.8 y (Mean ± SEM), 36.9 ± 0.5 kg/m2, 80.2% female, 62.2% non-Hispanic white. Baseline HbA1c, weight, and total DDS score were 8.0 ± 0.09%, 101.10 ± 1.47 kg, and 2.35 ± 0.08, respectively. At week 24, HbA1c, body weight, and total DDS decreased by 0.75 ± 0.11%, 5.74 ± 0.50%, 0.33 ± 0.10 units, respectively (all p
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- 2023
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4. Qualitative inquiry with persons with obesity about weight management in primary care and referrals
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Lisa Bailey-Davis, Angela Marinilli Pinto, David J. Hanna, Michelle I. Cardel, Chad D. Rethorst, Kelsey Matta, Christopher D. Still, and Gary D. Foster
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referral and consultation ,obesity ,obesity management ,qualitative research ,delivery of health care ,Public aspects of medicine ,RA1-1270 - Abstract
IntroductionReferrals to evidence-based weight management in the community-commercial sector are aligned with clinical recommendations but underutilized.MethodsThis qualitative study explored patients’ perceptions and expectations about obesity treatment in primary care and referral to community-commercial sector programs. Individual semi-structured interviews were conducted with a sample of US persons with obesity via telephone. Audiotape transcripts, interviewer notes, and independent review of data by two investigators allowed for data and investigator triangulation. Transcripts were analyzed using thematic analysis.ResultsData saturation was reached with 30 participants who had a mean age of 41.6 years (SD 9.4), 37% male, 20% Black/African American and 17% Hispanic, 57% college educated, and 50% were employed full-time. Three primary themes emerged: (1) frustration with weight management in primary care; (2) patients expect providers to be better informed of and offer treatment options; and (3) opportunities and challenges with referrals to community-commercial programs.DiscussionPatients expect that providers offer personalized treatment options and referrals to effective community-commercial programs are an acceptable option. If patient-level data are shared between clinical and community entities to facilitate referrals, then privacy and security issues need attention. Future research is needed to determine feasibility of implementing clinical to community-commercial referrals for obesity treatment in the United States.
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- 2023
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5. Feasibility/acceptability of an acceptance‐based therapy intervention for diverse adolescent girls with overweight/obesity
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Michelle I. Cardel, Alexandra M. Lee, Xiaofei Chi, Faith Newsome, Darci R. Miller, Angelina Bernier, Lindsay Thompson, Matthew J. Gurka, David M. Janicke, and Meghan L. Butryn
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adolescents ,feasibility ,intervention ,obesity ,Internal medicine ,RC31-1245 - Abstract
Abstract Background Behavioral obesity interventions using an acceptance‐based therapy (ABT) approach have demonstrated efficacy for adults, yet feasibility and acceptability of tailoring an ABT intervention for adolescents remains unknown. Objective This study assessed the feasibility and acceptability of an ABT healthy lifestyle intervention among diverse adolescent cisgender girls with overweight/obesity (OW/OB). Methods Adolescent cisgender girls aged 14–19 with a BMI of ≥85th percentile‐for‐sex‐and‐age were recruited for participation in a single‐arm feasibility study. The primary outcomes were recruitment and retention while the secondary outcome was change in BMI Z‐score over the 6‐month intervention. Exploratory outcomes included obesity‐related factors, health‐related behaviors, and psychological factors. Results Recruitment goals were achieved; 13 adolescents (>60% racial/ethnic minorities) participated in the intervention, and 11 completed the intervention (85% retention). In completers (n = 11), a mean decrease in BMI Z‐score of −0.15 (SD = 0.34, Cohen's d = −0.44) was observed. Improvements were also noted for change in percentage of 95th percentile (d = −0.35), percent body fat (d = −0.35), quality of life (d = 0.71), psychological flexibility (d = −0.86), and depression (d = −0.86). Conclusions These preliminary findings suggest an ABT healthy lifestyle intervention tailored for adolescent cisgender girls with OW/OB may be an acceptable treatment that could lead to improvements in BMI Z‐score, obesity‐related measures, and psychological outcomes.
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- 2021
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6. Perceived barriers/facilitators to a healthy lifestyle among diverse adolescents with overweight/obesity: A qualitative study
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Michelle I. Cardel, Sarah M. Szurek, Julia R. Dillard, Abhya Dilip, Darci R. Miller, Ryan Theis, Angelina Bernier, Lindsay A. Thompson, A. Dulin, David M. Janicke, and Alex M. Lee
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adolescence ,paediatric obesity intervention ,paediatric obesity ,weight management ,Internal medicine ,RC31-1245 - Abstract
Summary Objective Effectiveness of behavioural obesity treatments in adolescents is modest. Thus, incorporating participant feedback may lead to improvement of intervention acceptability. This qualitative study's objective was to assess perceived barriers/facilitators to weight loss and healthy lifestyles among diverse adolescents with overweight/obesity (OW/OB). Methods Adolescents ages 14–19 with BMI ≥ 85th percentile participated in focus groups and identified perceived barriers/facilitators to weight loss and healthy lifestyles. Results Ten sex‐stratified focus groups (n = 41; n = 13 males, n = 28 females) were conducted in 2018 and 2019. Females reported experiencing weight struggles, whereas males often stated no struggles with weight, despite all participants meeting criterion for OW/OB. Barriers included eating behaviours, family members and internal motivation, with additional barriers of physical activity, friends, time and support cited in females. Facilitators included parental, familial and peer support of healthy eating and exercise, modelling behaviours, internal motivation and organized sports. Two additional findings regarding adolescents' perceived barriers/facilitators include substantial overlap and sex differences of perceived barriers/facilitators. Conclusions Adolescent males and females with OW/OB experience weight status differently, affecting their perceived barriers/facilitators to weight loss and healthy lifestyles. Tailoring weight management interventions to the unique needs of adolescent females versus adolescent males has the potential to improve intervention quality and effectiveness.
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- 2020
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7. Biobehavioural approaches to prevention and treatment: A call for implementation science in obesity research
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Kathryn A. Kaiser, Tiffany L. Carson, Emily J. Dhurandhar, William H. Neumeier, and Michelle I. Cardel
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biobehavioural ,implementation science ,obesity ,Internal medicine ,RC31-1245 - Abstract
Summary Much progress has been made in the last 30 years in understanding the causes and mechanisms that contribute to obesity, yet widely available and successful strategies for prevention and treatment remain elusive at population levels. This paper discusses the biobehavioural framework and provides suggestions for applying it to enable greater progress in the science of obesity prevention and treatment, including an increased focus on implementation of science strategies. The objective is to promote a re‐evaluation of current views about preventing and treating obesity within a unified biobehavioural framework. Further integration of research exploring how both behavioural and biological components interact is a critical step forward.
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- 2020
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8. Pathways of Teach-Back Communication to Health Outcomes Among Individuals With Diabetes: A Pathway Modeling
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Young-Rock Hong, Ara Jo, Jinhai Huo, Michelle I. Cardel, and Arch G. Mainous
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Computer applications to medicine. Medical informatics ,R858-859.7 ,Public aspects of medicine ,RA1-1270 - Abstract
Teach-back method can help promote interactive communication between patients and providers. However, the mechanism of how teach-back operates in routine care is uninvestigated. Using pathway analysis, we explored the potential pathways of patient teach-back to health outcomes among individuals with diabetes. Study sample included 2901 US adults with diabetes ascertained from the 2011 to 2016 Longitudinal Medical Expenditure Panel Survey. Our pathway model analysis showed that patient teach-back was associated with better interaction with providers, shared decision-making, and receiving lifestyle advice. Teach-back had a direct negative effect on condition-specific hospitalization and indirect negative effects through lifestyle advice and diabetic complication. Teach-back method may promote active interactions between patients and providers by creating an opportunity to be more engaged in shared decision-making and receive additional health advice from providers. These improvements seem to be associated with a reduction in risks for complications and related hospitalization.
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- 2022
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9. Using self-monitoring technology for nutritional counseling and weight management
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Chelsea A Carpenter, Umelo A Ugwoaba, Michelle I Cardel, and Kathryn M Ross
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Self-monitoring of weight, dietary intake, and physical activity is a key strategy for weight management in adults with obesity. Despite research suggesting consistent associations between more frequent self-monitoring and greater success with weight regulation, adherence is often suboptimal and tends to decrease over time. New technologies such as smartphone applications, e-scales, and wearable devices can help eliminate some of the barriers individuals experience with traditional self-monitoring tools, and research has demonstrated that these tools may improve self-monitoring adherence. To improve the integration of these tools in clinical practice, the current narrative review introduces the various types of self-monitoring technologies, presents current evidence regarding their use for nutrition support and weight management, and provides guidance for optimal implementation. The review ends with a discussion of barriers to the implementation of these technologies and the role that they should optimally play in nutritional counseling and weight management. Although newer self-monitoring technologies may help improve adherence to self-monitoring, these tools should not be viewed as an intervention in and of themselves and are most efficacious when implemented with ongoing clinical support.
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- 2022
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10. Enabling Informed Decision Making in the Absence of Detailed Nutrition Labels: A Model to Estimate the Added Sugar Content of Foods
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Reka Daniel-Weiner, Michelle I. Cardel, Michael Skarlinski, Angela Goscilo, Carl Anderson, and Gary D. Foster
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obesity ,Nutrition and Dietetics ,diabetes ,machine learning in nutrition ,added sugar ,informed decisions ,Food Science - Abstract
Obesity and diabetes have emerged as an increasing threat to public health, and the consumption of added sugar can contribute to their development. Though nutritional content information can positively influence consumption behavior, added sugar is not currently required to be disclosed in all countries. However, a growing proportion of the world’s population has access to mobile devices, which allow for the development of digital solutions to support health-related decisions and behaviors. To test whether advances in computational science can be leveraged to develop an accurate and scalable model to estimate the added sugar content of foods based on their nutrient profile, we collected comprehensive nutritional information, including information on added sugar content, for 69,769 foods. Eighty percent of this data was used to train a gradient boosted tree model to estimate added sugar content, while 20% of it was held out to assess the predictive accuracy of the model. The performance of the resulting model showed 93.25% explained variance per default portion size (84.32% per 100 kcal). The mean absolute error of the estimate was 0.84 g per default portion size (0.81 g per 100 kcal). This model can therefore be used to deliver accurate estimates of added sugar through digital devices in countries where the information is not disclosed on packaged foods, thus enabling consumers to be aware of the added sugar content of a wide variety of foods.
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- 2023
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11. Racial and ethnic representation among a sample of nutrition- and obesity-focused professional organizations in the United States
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Steven K. Grinspoon, Fatima Cody Stanford, Takara L. Stanley, James O. Hill, Tiffany L. Carson, Elizabeth J. Mayer-Davis, Michelle I. Cardel, and Jamy D. Ard
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Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,Population ,Ethnic group ,Medicine (miscellaneous) ,Hawaii ,Article ,Endocrinology ,Cultural diversity ,Health care ,Obesity medicine ,Ethnicity ,Humans ,Obesity ,education ,Minority Groups ,media_common ,education.field_of_study ,Nutrition and Dietetics ,business.industry ,Racial Groups ,United States ,Perspective ,Pacific islanders ,Professional association ,business ,Psychology ,Societies ,Demography ,Diversity (politics) - Abstract
OBJECTIVE: Obesity is a chronic disease that disproportionately affects individuals from nonmajority racial/ethnic groups in the United States. Research shows that individuals from minority racial/ethnic backgrounds consider it important to have access to providers from diverse backgrounds. Health care providers and scientists from minority racial/ethnic groups are more likely than their non-Hispanic White counterparts to treat or conduct research on patients from underrepresented groups. The objective of this study was to characterize the racial/ethnic diversity of nutrition- and obesity-focused professional organizations in the United States. METHODS: This study assessed race/ethnicity data from several obesity-focused national organizations including The Obesity Society, the Academy of Nutrition and Dietetics (AND), the American Society for Nutrition, and the American Board of Obesity Medicine (ABOM). Each organization was queried via emailed survey to provide data on racial/ethnic representation among their membership in the past 5 years and among elected presidents from 2010 to 2020. RESULTS: Two of the three professional societies queried did not systematically track race/ethnicity data at the time of query. Limited tracking data available from AND show underrepresentation of Black (2.6%), Asian (3.9%), Latinx (3.1%), Native Hawaiian or Pacific Islander (1.3%), or indigenous (American Indian or Alaskan Native: 0.3%) individuals compared with the US population. Underrepresentation of racial/ethnic minorities was also reported for ABOM diplomates (Black: 6.0%, Latinx: 5.0%, Native American: 0.2%). Only AND reported having racial/ethnic diversity (20%) among the organization’s presidents within the previous decade (2010–2020). CONCLUSIONS: Findings suggest that (1) standardized tracking of race and ethnicity data is needed to fully assess diversity, equity, and inclusion, and (2) work is needed to increase the diversity of membership and leadership at the presidential level within obesity- and nutrition-focused professional organizations. A diverse cadre of obesity- and nutrition-focused health care professionals is needed to further improve nutrition-related health outcomes, including obesity, cardiovascular disease, diabetes, and undernutrition, in this country.
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- 2021
12. Time Equivalency and Child Adiposity: The Biggest Bang for the Buck
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Michelle I. Cardel, Faith A. Newsome, and Joseph A. Skelton
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Gerontology ,medicine.medical_specialty ,business.industry ,Public health ,MEDLINE ,Physical activity ,medicine.disease ,Health outcomes ,Obesity ,Health informatics ,Childhood obesity ,Article ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,030225 pediatrics ,Pediatrics, Perinatology and Child Health ,medicine ,business - Abstract
* Abbreviations: HRQoL — : health-related quality of life MVPA — : moderate-vigorous physical activity The public health, medical, and research community has increased focus on childhood obesity over the past few decades and for good reason. Obesity prevalence is at an all-time high,1 and rates of severe obesity continue to increase.2 Activity, both sedentary and physical, are key contributors to the development and treatment of obesity.3–5 Increasing physical activity while decreasing sedentary activity is an obvious goal in improving the weight and health of children. Unfortunately, the majority of children in the United States are not receiving the recommended amounts of physical activity and surpassing suggested limits on sedentary activity.6 Because there are finite hours in a day, increasing time spent on 1 activity will require doing less of another (ie, replacing one activity with another). In the case of activity, it is assumed that increased time spent engaged in physical activity is always beneficial, without the recognition that it may detract from other important life and health components (eg, sleep and school work). Exploring how individuals allocate their time may provide insight into how one can increase time spent in a beneficial behavior (eg, exercise), without stealing that time from an activity that is also beneficial (eg, sleep). In their study, Ng et al7 approached this topic through the lens of time and in relation … Address correspondence to Michelle I. Cardel, PhD, MS, RD, Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, 2197 Mowry Rd, Gainesville, FL 32607. E-mail: mcardel{at}ufl.edu
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- 2021
13. Psychological Resilience, Experimentally Manipulated Social Status, and Dietary Intake among Adolescents
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Victoria Williamson, Darci Miller, Michelle I. Cardel, Tianyao Huo, Alexandra M Lee, and Jon K. Maner
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Male ,Pediatric Obesity ,obesity ,Adolescent ,media_common.quotation_subject ,eating behaviors ,Hispanic american ,030209 endocrinology & metabolism ,lcsh:TX341-641 ,Overweight ,Affect (psychology) ,Article ,socioeconomic status ,Eating ,03 medical and health sciences ,0302 clinical medicine ,Games, Recreational ,medicine ,Humans ,overweight ,Socioeconomic status ,media_common ,youth ,030505 public health ,Nutrition and Dietetics ,business.industry ,Dietary intake ,Feeding Behavior ,Hispanic or Latino ,Resilience, Psychological ,medicine.disease ,Obesity ,United States ,social status ,Hispanic American ,Lunch ,Psychological Distance ,Female ,Psychological resilience ,medicine.symptom ,racial/ethnic minority ,0305 other medical science ,business ,Hispanic/Latino ,lcsh:Nutrition. Foods and food supply ,Food Science ,Demography ,Social status - Abstract
Relative to other racial/ethnic groups in the United States, Hispanic American (HA) youth have higher rates of overweight and obesity. Previous work suggests that low perceived social status (SS) promotes excess caloric intake and, thereby, development of obesity. Psychological resilience may play a role in reducing adverse eating behaviors and risk for obesity. The objective of this study was to investigate whether resilience (as measured by the Connor Davidson Resilience Scale) interacts with experimentally manipulated SS to affect dietary intake among HA adolescents (N = 132). Using a rigged game of Monopoly (Hasbro, Inc.), participants were randomized to a high or low SS condition. Following the Monopoly game, participants consumed an ad libitum lunch and their dietary intake was assessed. There was a significant interaction between resilience and experimentally manipulated SS for total energy intake (p = 0.006), percent energy needs consumed (p = 0.005), and sugar intake (p = 0.004). For the high SS condition, for each increase in resilience score, total energy intake decreased by 7.165 ± 2.866 kcal (p = 0.014) and percent energy needs consumed decreased by 0.394 ± 0.153 (p = 0.011). In the low SS condition, sugar intake increased by 0.621 ± 0.240 g for each increase in resilience score (p = 0.011). After correction for multiple comparisons, the aforementioned interactions, but not simple slopes, were statistically significant.
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- 2021
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14. The Relationship between Objective and Subjective Measures of Socioeconomic Status on Metabolic Syndrome Severity Among African American Adults
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Mark D. DeBoer, Michelle I. Cardel, and Matthew J. Gurka
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African american ,Gerontology ,Adult ,Metabolic Syndrome ,Endocrine and Autonomic Systems ,Extramural ,business.industry ,Endocrinology, Diabetes and Metabolism ,MEDLINE ,Social class ,medicine.disease ,Article ,Black or African American ,Psychiatry and Mental health ,Endocrinology ,Socioeconomic Factors ,Social Class ,Medicine ,Humans ,Longitudinal Studies ,Metabolic syndrome ,business ,Socioeconomic status ,Biological Psychiatry - Published
- 2020
15. COVID‐19 Impacts Mental Health Outcomes and Ability/Desire to Participate in Research Among Current Research Participants
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Stephanie Manasse, Young-Rock Hong, Dominick J. Lemas, Michelle I. Cardel, Rebecca A. Krukowski, Rebecca Shakour, Kathryn M. Ross, and Darci Miller
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Adult ,Male ,medicine.medical_specialty ,Cross-sectional study ,Research Subjects ,Endocrinology, Diabetes and Metabolism ,Medicine (miscellaneous) ,030209 endocrinology & metabolism ,behavioral science ,psychology ,Anxiety ,outcomes ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Intervention (counseling) ,Surveys and Questionnaires ,Epidemiology ,Health care ,Outcome Assessment, Health Care ,medicine ,Humans ,030212 general & internal medicine ,Depression (differential diagnoses) ,Nutrition and Dietetics ,business.industry ,Depression ,SARS-CoV-2 ,COVID-19 ,Original Articles ,Middle Aged ,Mental health ,Distress ,Cross-Sectional Studies ,Mental Health ,clinical research ,Original Article ,epidemiology ,Female ,medicine.symptom ,business ,Stress, Psychological ,Clinical psychology - Abstract
Objective This study aimed to examine the impact of coronavirus disease 2019 (COVID-19) on current research participants' mental health outcomes, ability to adhere to behavioral intervention recommendations, and desire to participate in research. Methods A quantitative/qualitative cross-sectional survey was used among adults currently enrolled in health-related research (N = 250; 85% women; > 50% currently enrolled in behavioral weight loss intervention). Results COVID-19 was perceived as a severe threat by most (62.3%). Related to COVID-19, 29.6% of participants reported moderate/severe symptoms of anxiety/depression, and 68.4% reported moderate/severe posttraumatic stress disorder (PTSD) symptomatology, with women more likely to demonstrate moderate/severe anxiety/depression (P = 0.047) and PTSD symptomatology (P = 0.028) relative to men. Those with moderate/severe levels of anxiety/depression (P = 0.0154) and distress (P = 0.0330) were more likely to report a decreased desire to participate in research. Among those in behavioral interventions, individuals perceiving COVID-19 as a moderate/severe threat or experiencing moderate/severe depression or PTSD symptomatology were 4 to 19 times more likely to report that COVID-19 affected their ability to adhere to behavioral recommendations. Qualitative analysis identified four themes describing COVID-19's impact on research experiences: transition, remote intervention delivery, ability to adhere to program goals, and research participation interest. Conclusions These data suggest that participants engaged in health-related research perceive COVID-19 as a significant threat, affecting mental health, desire to participate in research, and ability to adhere to intervention recommendations.
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- 2020
16. Traffic Light Diets Per Se Have Limited Evidence for Effectiveness on Childhood Obesity: A Review
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Andrew W. Brown, Michelle I. Cardel, Michelle M Bohan Brown, and Colby J. Vorland
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Nutrition and Dietetics ,Peanut butter ,business.industry ,Life style ,Medicine (miscellaneous) ,medicine.disease ,Obesity ,Childhood obesity ,Traffic signal ,Weight loss ,Environmental health ,medicine ,Limited evidence ,medicine.symptom ,business ,Food Science - Abstract
OBJECTIVES: The “traffic light diet” (TLD; or “stop light diet” among other names) categorizes foods into ‘green’, ‘yellow’, or ‘red’ groups to consume without restriction, in moderation, or minimally, respectively. It is often a component of childhood interventions targeting weight-related outcomes. The Academy of Nutrition and Dietetics Evidence Analysis Library assigned TLDs Grade I evidence in 2006 for pediatric weight management, but none of the studies reviewed tested the TLD in isolation. We conducted a review of the effect of TLDs on obesity-related outcomes in children and definitions among different implementations of TLDs. METHODS: We searched PubMed up to September 2019 for interventions using the TLD with obesity-related anthropometric outcomes. Studies were screened in duplicate, and treatment characteristics extracted. Additional studies were identified by screening references. Using a convenience sample of texts from the original TLD creators, Indiana University vending, a new pediatric weight loss app, and an online resource, we assessed how definitions of TLDs compare. RESULTS: Our search identified 386 abstracts, 5 of which were interventions that included the TLD and weight-related outcomes. Three of these were randomized controlled trials, and none studied the TLD in isolation outside of multicomponent interventions. We then focused on 4 foundational TLD articles that were repeatedly cited. One of these isolated the TLD from the multicomponent intervention but found no statistical effect of the diet or interaction of diet with other factors for weight-related outcomes. In the sample of TLD implementations, substantial differences were apparent in how foods were classified among green, yellow, and red groups, such as avocados, nuts, figs/fig cookies, and peanut butter. CONCLUSIONS: There is insufficient evidence supporting TLDs as a unique, isolatable factor in improving weight-related outcomes in children. This does not necessarily mean that TLDs are ineffective, as they have been incorporated into successful interventions. A standardization of TLD definitions (consistently categorizing foods and whether the term ‘TLD’ is meant to include other components of an intensive lifestyle intervention) is needed to make comparisons of effectiveness going forward. FUNDING SOURCES: The authors received no funding for this specific work.
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- 2020
17. Turning Chutes into Ladders for Women Faculty: A Review and Roadmap for Equity in Academia
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Leslie A. McClure, Bertha Hidalgo, Emily J. Dhurandhar, Noha Sharafeldin, Michelle I. Cardel, Sherry L. Pagoto, Amanda L. Willig, Monica Foster, Christine Angelini, Ceren Yarar-Fisher, Dori Pekmezi, and Nathanial P. Brown
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Gender equity ,Economic growth ,education ,Sexism ,03 medical and health sciences ,0302 clinical medicine ,ComputingMilieux_COMPUTERSANDEDUCATION ,Medicine ,Humans ,030212 general & internal medicine ,health care economics and organizations ,Equity (economics) ,ComputingMilieux_THECOMPUTINGPROFESSION ,business.industry ,Salaries and Fringe Benefits ,05 social sciences ,050301 education ,General Medicine ,Original Articles ,Faculty ,United States ,Career Mobility ,Leadership ,ComputingMilieux_COMPUTERSANDSOCIETY ,Female ,Implicit bias ,business ,0503 education - Abstract
Despite significant progress in recent decades, the recruitment, advancement, and promotion of women in academia remain low. Women represent a large portion of the talent pool in academia, and receive >50% of all PhDs, but this has not yet translated into sustained representation in faculty and leadership positions. Research indicates that women encounter numerous “chutes” that remove them from academia or provide setbacks to promotion at all stages of their careers. These include the perception that women are less competent and their outputs of lesser quality, implicit bias in teaching evaluations and grant funding decisions, and lower citation rates. This review aims to (1) synthesize the “chutes” that impede the careers of women faculty, and (2) provide feasible recommendations, or “ladders” for addressing these issues at all career levels. Enacting policies that function as “ladders” rather than “chutes” for academic women is essential to even the playing field, achieve gender equity, and foster economic, societal, and cultural benefits of academia.
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- 2020
18. Objective and Subjective Socioeconomic Status Associated with Metabolic Syndrome Severity among African American Adults in Jackson Heart Study
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Darci Miller, Mario Sims, Mark D. DeBoer, Gregory Pavela, Matthew J. Gurka, Xiaofei Chi, Akilah Dulin, Michelle I. Cardel, and Yi Guo
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African american ,Endocrine and Autonomic Systems ,business.industry ,Endocrinology, Diabetes and Metabolism ,medicine.disease ,Article ,030227 psychiatry ,SSS ,03 medical and health sciences ,Psychiatry and Mental health ,0302 clinical medicine ,Endocrinology ,Cohort ,Medicine ,Social determinants of health ,Metabolic syndrome ,business ,Psychosocial ,Socioeconomic status ,030217 neurology & neurosurgery ,Biological Psychiatry ,Demography ,Social status - Abstract
Purpose To assess independent associations between objective socioeconomic status (OSS) and subjective social status (SSS) with metabolic syndrome (MetS) severity and indicators among African American (AA) adults in the Jackson Heart Study (JHS) at baseline (2000–2004) and eight-year follow-up (2009–2013). Methods Participants included 1724 AA adults from the JHS cohort (64.4 % women; mean age 53.4 ± 11.8). Associations of OSS (annual household income and school years completed) and SSS (measured with MacArthur Scales) with sex- and race/ethnic-specific MetS severity Z-score were examined after adjustment for demographics and MetS risk factors (i.e., nutrition, physical activity, smoking status, alcohol consumption, and depressive symptoms) at baseline and eight-year follow-up. Principal results Independent of OSS, demographic, psychosocial, and lifestyle factors, individuals with lower US-society SSS had more severe MetS at baseline. A significant interaction existed between sex and US-society SSS such that women with lower perceived social status had more severe MetS severity at baseline, and for every one unit increase in US-society SSS, MetS severity Z-score is estimated to decrease by 0.04. Components of MetS driving the relationship between US-society SSS and MetS severity at baseline were the inverse associations of SSS with glucose levels and the positive associations of SSS with HDL-C. Physical activity was independently associated with MetS severity at baseline, but not at eight-year follow-up. Major conclusions Though subjective and objective measures of social status are independently associated with cardiometabolic risk factors and MetS severity among AA adults, SSS may be a stronger predictor of MetS severity than OSS, particularly among women. SSS should be considered in conjunction with OSS when exploring social determinants of cardiometabolic health.
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- 2020
19. Diet quality and dental caries in the Hispanic Community Health Study/Study of Latinos
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Daniela Sotres-Alvarez, Nadia Laniado, Tracy L. Finlayson, Krista M. Perreira, Linda M. Kaste, Michelle I. Cardel, and Anne E. Sanders
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Adult ,Male ,medicine.medical_specialty ,Adult population ,Healthy eating ,Dental Caries ,Whole grains ,Article ,03 medical and health sciences ,0302 clinical medicine ,Environmental health ,Epidemiology ,Medicine ,Humans ,General Dentistry ,030505 public health ,business.industry ,Public Health, Environmental and Occupational Health ,030206 dentistry ,Hispanic or Latino ,Anthropometry ,Confidence interval ,Diet ,Cross-Sectional Studies ,Diet quality ,Community health ,Female ,Public Health ,0305 other medical science ,business - Abstract
OBJECTIVES: Fermentable carbohydrate is universally recognized as the major dietary risk factor for dental caries. We assessed the broader relationship between diet quality and dental caries in a diverse Latinx adult population. METHODS: In a cross-sectional probability sample, 14,517 dentate men and women in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) received a dental examination and completed two 24-hours dietary recalls and a food propensity questionnaire. The 2010 Alternative Healthy Eating Index (AHEI) assessed diet quality and the National Cancer Institute method predicted usual intake of the 11 dietary components that comprise the AHEI. Dental caries experience was quantified using the decayed, missing and filled surfaces (DMFS) index. Covariates included sociodemographic and anthropometric characteristics. Survey multivariable-adjusted linear regression models quantified the relationship of 2010 AHEI score, and its 11 components, with DMFS. RESULTS: In multivariable-adjusted models, each 10-unit increase in diet quality score was associated with 2.5 fewer (95% confidence interval: −3.4, −1.6) DMFS. The relationship was pronounced among foreign-born individuals, who com-prised three-quarters of the sample, irrespective of their length of US residence, but was not apparent among U.S.-born individuals. Greater intake of sugar-sweetened beverage and fruit juice was positively associated with dental caries, whereas vegetables (excluding potatoes); whole grains; and omega-3 fats were inversely associated with dental caries, independent of covariates and the other dietary components (all P < 0.05). CONCLUSIONS: An association between diet quality and dental caries was restricted to foreign-born Latinix and was not limited to the adverse impact of sugar-sweetened drinks.
- Published
- 2020
20. The Effect of n-3 Polyunsaturated Fatty Acids on the Components of Metabolic Syndrome, a Systematic Review and Meta-Analysis of Randomized Controlled Trials (P08-037-19)
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Changjun Yang, Tianyao Huo, Michelle I. Cardel, Matthew J. Gurka, and Andrew W. Brown
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chemistry.chemical_classification ,Nutrition and Dietetics ,business.industry ,Medicine (miscellaneous) ,medicine.disease ,Bioinformatics ,law.invention ,chemistry ,Randomized controlled trial ,law ,Meta-analysis ,Medicine ,Energy and Macronutrient Metabolism ,Metabolic syndrome ,business ,Food Science ,Polyunsaturated fatty acid - Abstract
OBJECTIVES: Intake of n-3 polyunsaturated fatty acids (PUFAs) has been reported to provide various benefits for patients with metabolic syndrome (MetS), such as reducing blood pressure and improving blood lipids, but results are inconsistent. This study aimed to investigate the effect of n-3 PUFA intake on components of MetS. METHODS: We searched PubMed, Scopus, Web of Sciences, and Cochrane databases up to June 2018 for randomized trials at least 30 days long comparing n-3 PUFAs with a control in patients diagnosed with MetS (PROSPERO registration ID: CRD42017072332). The outcomes include body mass index, systolic and diastolic blood pressure, triglyceride, high-density lipoprotein cholesterol, and fasting blood glucose. Mean differences post-intervention or mean change from baseline were combined using random-effects models; confirmation of within-study effect sizes is ongoing. RESULTS: A total of 14 trials were identified. The pooled results showed n-3 PUFA intake reduced systolic blood pressure by 3.92 mmHg (95%CI: –6.89, –0.96, P-value = 0.009, I2 = 34%, 9 trials) and diastolic blood pressure by 2.81 mmHg (95%CI: –4.26, –1.36, P-value = 0.0001, I2 = 15%, 8 trials). Body mass index was lower in the n-3 PUFA group by 3.19 kg/m2 (95%CI: –6.16, –0.22, P-value = 0.04, I2 = 97%, 7 trials) compared to the control group. Triglyceride levels in n-3 PUFA groups were significantly lower than the control when pooling trials with post intervention data only (–33.13 mg/dL, 95%CI: –49.44, –16.81, P-value
- Published
- 2019
21. The Effects of Experimentally Manipulated Social Status and Food Insecurity on Acute Eating Behavior and Risk for Obesity Among Adolescents: A Randomized Controlled Study (P21-058-19)
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Ann Caldwell, Tianyao Huo, Gregory Pavela, Darci Miller, Alicia Fernandez, Eric G. Krause, Michelle I. Cardel, Matthew J. Gurka, David M. Janicke, Akilah Dulin, Emily J. Dhurandhar, John C. Peters, David B. Allison, Alexandra M Lee, and Paul K. Piff
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Nutrition and Dietetics ,Calorie ,business.industry ,media_common.quotation_subject ,Medicine (miscellaneous) ,medicine.disease ,Obesity ,law.invention ,Food insecurity ,Blood pressure ,Randomized controlled trial ,Feeling ,law ,Environmental health ,Heart rate ,Medicine ,business ,Food Science ,media_common ,Social status - Abstract
OBJECTIVES: Subjective and objective social status is associated with weight status, but this relationship differs by sex and the mechanisms remain unclear. METHODS: This randomized study in Hispanic adolescents investigated the effects of experimentally manipulated social status on ad libitum acute and 24-hour dietary intakes and stress-related outcomes as potential mechanisms through which social status affects weight. Participants (n = 133; ages 15–21; 60.2% girls; BMI ≥18.5 and ≤40 kg/m(2); 23.4% food insecure) consumed a standardized breakfast and then were randomized to a low (LOW) or high social status position (HIGH) in a rigged game of Monopoly™, in which the rules differed substantially by social status position. Following the game, the participants consumed an ad libitum lunchtime meal. Energy intake was assessed by pre- and post- food weighing. Stress-related markers were measured at baseline, before Monopoly™, after Monopoly™, and after lunch, with the exception of cortisol (measured before and after Monopoly™). RESULTS: There was a significant interaction between sex and experimentally manipulated social status (P = 0.0087), such that girls randomized to LOW consumed significantly more of their daily energy needs at the ad libitum lunchtime meal relative to those randomized to HIGH (37.5% vs. 34.3%, respectively). Individuals with food insecurity consumed a greater % of their daily energy needs at the lunchtime meal than those with food security, although the result was not quite statistically significant (40.7% vs. 36.3%, respectively; P = 0.08). In LOW, participants report decreased feelings of powerfulness following Monopoly™ (P = 0.0006). There were no significant differences between HIGH and LOW following Monopoly™ regarding perceived stress, cortisol, heart rate, or blood pressure. Social status condition was not related to 24-hour % of daily energy needs consumed. CONCLUSIONS: Our data suggest a causal link between experimentally manipulated low social status and increased acute energy intakes among Hispanic girls, potentially influenced by decreased feelings of powerfulness, which is independent of stress. Low social status may play a causal role in the development of obesity by promoting excess calorie consumption. Further research is needed to identify the biobehavioral mechanisms contributing to this phenomenon. FUNDING SOURCES: NIH. SUPPORTING TABLES, IMAGES AND/OR GRAPHS
- Published
- 2019
22. Subjective Social Status is associated with compensation for large meals – a prospective pilot study
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Bridget Ironuma, Candice A. Myers, Bailey Rusinovich, Corby K. Martin, David B. Allison, John A. Dawson, Emily J. Dhurandhar, Nadeeja Wijayatunga, Michelle I. Cardel, and Gregory Pavela
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Adult ,Energy balance ,Pilot Projects ,Overweight ,Article ,Body Mass Index ,Medicine ,Humans ,Resting energy expenditure ,Prospective Studies ,General Psychology ,Meal ,Nutrition and Dietetics ,business.industry ,Nutritional Requirements ,Feeding Behavior ,medicine.disease ,Obesity ,SSS ,Lunch ,Social Class ,Female ,medicine.symptom ,business ,Energy Intake ,Body mass index ,Weight gain ,Demography - Abstract
Objectives Subjective social status (SSS) is known to be inversely associated with obesity. Our objective was to determine if SSS is associated with eating behaviors that would predispose to weight gain, specifically, with inadequate compensation for excess energy consumed during a single large meal. Therefore, we conducted a pilot study to determine the association of SSS with 24-h energy balance, 24-h and post-lunch energy intake, changes in body composition and changes in adjusted resting energy expenditure on days when a high-energy lunch was consumed in free-living human subjects. Method Female participants (7 normal weight and 10 overweight) consumed 60% of’ estimated 24-h energy requirements as a lunchtime meal in the laboratory for 14 days. Subjective social status was measured at baseline using the MacArthur Scale. Remote Food Photography Method was used to record food intake outside of the lab on days 1–2, 7–8, and 12–13. Associations of 24-h energy balance, 24-h and post-lunch energy intake, changes in adjusted resting energy expenditure and changes in percent body fat (measured by dual x-ray absorptiometry) with SSS were studied. Results Mean (standard deviation) age and BMI were 36.29 (8.25) years and 26.43 (2.32) kg/m2, respectively. Lower SSS was significantly associated with positive energy balance (p for trend 0.002), and higher post-lunch energy intake (p = 0.02) when controlled for age and initial body mass index. Conclusions Our pilot data show that lower SSS is associated with higher post-lunch energy intake, which is indicative of poor energy compensation following a large meal. Over a longer time period, this could result in fat mass gain. Studies that are of longer duration and well-powered are warranted to confirm our findings.
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- 2018
23. Future Research Directions for the Insurance Hypothesis regarding Food Insecurity and Obesity
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Michelle I. Cardel, David B. Allison, Emily J. Dhurandhar, and Greg Pavela
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0301 basic medicine ,030109 nutrition & dietetics ,Physiology ,Ethnic group ,medicine.disease ,Obesity ,Article ,Food insecurity ,03 medical and health sciences ,Behavioral Neuroscience ,Race (biology) ,0302 clinical medicine ,Neuropsychology and Physiological Psychology ,Environmental health ,medicine ,030212 general & internal medicine ,Psychology ,Body mass index - Abstract
The focus of this commentary is Nettle et al.'s insurance hypothesis linking food insecurity to a high body mass index (BMI). We discuss how the relationship between race/ethnicity and obesity in the United States is consistent with this hypothesis, then present potential ways forward to elucidate the validity of this hypothesis in humans through rigorous controlled trials.
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- 2017
24. Multidisciplinary intervention in obese adolescents: predictors of dropout
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Wagner Luiz do Prado, Ricardo Luís Fernandes Guerra, Mara Cristina Lofrano-Prado, José Cazuza de Farias Júnior, Yara Lucy Fidelix, and Michelle I. Cardel
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Gerontology ,Male ,Pediatrics ,lcsh:Medicine ,Body Mass Index ,Nutrition Policy ,Surveys and Questionnaires ,Medicine ,Lipídeos ,Adolescente ,Adiposity ,Artigo Original ,Age Factors ,General Medicine ,Combined Modality Therapy ,Lipids ,Anorexia ,Eating disorders ,Skinfold Thickness ,Transtornos da alimentação ,Pacientes desistentes do tratamento ,Psychotherapy, Group ,Anxiety ,Patient dropouts ,Original Article ,Female ,medicine.symptom ,Quality of life ,medicine.medical_specialty ,Patient Dropouts ,Adolescent ,Hypercholesterolemia ,Qualidade de vida ,Humans ,Obesity ,Exercise ,Binge eating ,business.industry ,Adiposidade ,lcsh:R ,Cardiorespiratory fitness ,Odds ratio ,medicine.disease ,Adolescent Behavior ,Exercise Test ,Patient Compliance ,business ,Body mass index - Abstract
Objective To identify biological and psychosocial factors associated with dropout in a multidisciplinary behavioral intervention in obese adolescents.Methods A total of 183 adolescents (15.4±1.6 years), pubertal (Tanner stage 3 or 4) and obese (34.7±4.0kg/m2), were enrolled in a 12-week behavioral intervention, which included clinical consultations (monthly), nutritional and psychological counseling (once a week), and supervised aerobic training (three times/week). The studied variables were weight, height, body mass index, body composition (skinfold), cardiorespiratory fitness (direct gas analysis), blood lipids and self-reported symptoms of eating disorders (bulimia, anorexia and binge eating), anxiety, depression, body image dissatisfaction and quality of life. Statistical analysis included binary logistic regression and independent t-tests.Results Of the adolescents, 73.7% adhered to the program. The greatest chance for dropout was observed among adolescents older than 15 years (odds ratio of 0.40; 95%CI: 0.15-0.98), with more anorexia symptoms (odds ratio of 0.35; 95%CI: 0.14-0.86) and hypercholesterolemia (odds ratio of 0.40; 95%CI: 0.16-0.91) at baseline.Conclusion Older adolescents, with more symptoms of eating disorders and total cholesterol have less chance to adhere to multidisciplinary treatments. Objetivo Identificar os fatores biológicos e psicossociais associados à desistência de uma intervenção multidisciplinar comportamental em adolescentes obesos.Métodos Foram selecionados para participar das 12 semanas de intervenção 183 adolescentes (15,4±1,6 anos), púberes (Tanner 3 ou 4) e obesos (34,7±4,0 kg/m2). A intervenção incluiu consultas clínicas (mensal), aconselhamento nutricional e psicológico (uma vez/semana), e treinamento aeróbio supervisionado (três vezes/semana). As variáveis estudadas foram peso, altura, índice de massa corporal, composição corporal (dobras cutâneas), aptidão cardiorrespiratória (análise direta de gases), perfil lipídico e sintomas autorrelatados de transtornos alimentares (bulimia, anorexia e compulsão alimentar), ansiedade, depressão, insatisfação com a imagem corporal e qualidade de vida. A análise estatística incluiu regressão logística binária e teste tde Student independente.Resultados Aderiram ao programa 73,7% dos adolescentes. A maior chance de desistência foi observada entre aqueles com mais de 15 anos (odds ratiode 0,40; IC95%: 0,15-0,98), com mais sintomas de anorexia (odds ratio de 0,35; IC95%: 0,14-0,86) e com hipercolesterolemia (odds ratio de 0,40; IC95%: 0,16-0,91) no início do estudo.Conclusão Adolescentes mais velhos, com mais sintomas de transtornos alimentares e de níveis de colesterol total, têm menor chance de aderir a tratamentos multidisciplinares.
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- 2015
25. Parental feeding practices and socioeconomic status are associated with child adiposity in a multi-ethnic sample of children
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Krista Casazza, T. Mark Beasley, Michelle I. Cardel, Akilah Dulin-Keita, Amanda L. Willig, and Jose R. Fernandez
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Male ,Parents ,Pediatrics ,medicine.medical_specialty ,Cross-sectional study ,Population ,Ethnic group ,Abdominal Fat ,Social class ,Choice Behavior ,Article ,White People ,Eating ,Absorptiometry, Photon ,Prevalence ,Medicine ,Humans ,Obesity ,education ,Child ,Socioeconomic status ,General Psychology ,Adiposity ,education.field_of_study ,Nutrition and Dietetics ,Parenting ,business.industry ,Body Weight ,Feeding Behavior ,Hispanic or Latino ,medicine.disease ,Black or African American ,Cross-Sectional Studies ,Social Class ,Pressure to eat ,Body Composition ,Female ,Parental feeding ,business ,Demography - Abstract
Parental feeding practices have been associated with children's weight status, but results have been inconsistent across populations. Research is needed to elucidate the relationship between parental feeding practices and adiposity in diverse populations. The present study tested if: (1) parental feeding practices differed by race/ethnicity, (2) parental pressure to eat and parental restriction were associated with adiposity levels, and (3) to investigate the relationship between parental feeding practices and/or child adiposity with socioeconomic status (SES). Structural equations modeling was conducted to test the model in 267 children aged 7-12 years self-identified as African American (AA), European American (EA), or Hispanic American (HA) from economically diverse backgrounds. Dual energy X-ray absorptiometry and computed tomography scanning were used to determine body composition and abdominal fat distribution, respectively. Parental restriction was a significant predictor of child adiposity while parental pressure to eat had an inverse relationship with child adiposity. HA parents reported significantly higher levels of restriction and pressure to eat, whereas EA parents reported the lowest. SES was positively associated with child adiposity and inversely related to parental restriction and pressure to eat. Thus, parental feeding practices differ across racial/ethnic groups and SES and may contribute to population differences in child adiposity.
- Published
- 2011
26. Associations among calcium intake, resting energy expenditure, and body fat in a multiethnic sample of children
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T. Mark Beasley, Lynae J. Hanks, Krista Casazza, Michelle I. Cardel, Amanda L. Willig, and Jose R. Fernandez
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Male ,medicine.medical_specialty ,Rest ,chemistry.chemical_element ,Adipose tissue ,Calcium ,Article ,White People ,Fat accumulation ,Internal medicine ,medicine ,Humans ,Resting energy expenditure ,Dietary calcium ,Child ,Dual-energy X-ray absorptiometry ,medicine.diagnostic_test ,business.industry ,Total body ,Hispanic or Latino ,Black or African American ,Calcium, Dietary ,Endocrinology ,chemistry ,Adipose Tissue ,Pediatrics, Perinatology and Child Health ,Female ,business ,Energy Metabolism ,Body mass index - Abstract
Objective The objective was to determine if calcium intake was associated with resting energy expenditure (REE) and body fat in children after accounting for ancestral genetic background. Study design Participants included 315 children. REE, body composition, and dietary calcium were assessed by indirect calorimetry, dual-energy x-ray absorptiometry, and 24-hour recalls, respectively. Structural equations modeling assessed the relationships among REE, calcium intake, and body fat. Results There were positive associations between calcium intake and REE (P < .01) and between REE and total body fat (P < .0001). There was indirect effect of calcium intake on total body fat (P < .01). There were positive associations between calcium intake and REE (P < .01), and a trend toward an association of calcium intake and total body fat (P = .065) among boys only, whereas the only significant relationship among girls was an association of REE on total body fat (P < .0001). Conclusions REE was associated with calcium intake and mediated a relationship between calcium intake and total body fat. These findings suggest calcium intake may play a role in fat accumulation and energy balance through its effects on REE, especially in boys. (J Pediatr 2010;157:473-8).
- Published
- 2010
27. An Evaluation of a Personalized Multicomponent Commercial Digital Weight Management Program: Single-Arm Behavioral Trial
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Sherry Pagoto, Ran Xu, Tiffany Bullard, Gary D Foster, Richard Bannor, Kaylei Arcangel, Joseph DiVito, Matthew Schroeder, and Michelle I Cardel
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Computer applications to medicine. Medical informatics ,R858-859.7 ,Public aspects of medicine ,RA1-1270 - Abstract
BackgroundDigital behavioral weight loss programs are scalable and effective, and they provide an opportunity to personalize intervention components. However, more research is needed to test the acceptability and efficacy of personalized digital behavioral weight loss interventions. ObjectiveIn a 6-month single-arm trial, we examined weight loss, acceptability, and secondary outcomes of a digital commercial weight loss program (WeightWatchers). This digital program included a personalized weight loss program based on sex, age, height, weight, and personal food preferences, as well as synchronous (eg, virtual workshops and individual weekly check-ins) and asynchronous (eg, mobile app and virtual group) elements. In addition to a personalized daily and weekly PersonalPoints target, the program provided users with personalized lists of ≥300 ZeroPoint foods, which are foods that do not need to be weighed, measured, or tracked. MethodsWe conducted a pre-post evaluation of this 6-month, digitally delivered, and personalized WeightWatchers weight management program on weight loss at 3 and 6 months in adults with overweight and obesity. The secondary outcomes included participation, satisfaction, fruit and vegetable intake, physical activity, sleep quality, hunger, food cravings, quality of life, self-compassion, well-being, and behavioral automaticity. ResultsOf the 153 participants, 107 (69.9%) were female, and 65 (42.5%) identified as being from a minoritized racial or ethnic group. Participants’ mean age was 41.09 (SD 13.78) years, and their mean BMI was 31.8 (SD 5.0) kg/m2. Participants had an average weight change of −4.25% (SD 3.93%) from baseline to 3 months and −5.05% (SD 5.59%) from baseline to 6 months. At 6 months, the percentages of participants who experienced ≥3%, ≥5%, and ≥10% weight loss were 63.4% (97/153), 51% (78/153), and 14.4% (22/153), respectively. The mean percentage of weeks in which participants engaged in ≥1 aspects of the program was 87.53% (SD 23.40%) at 3 months and 77.67% (SD 28.69%) at 6 months. Retention was high (132/153, 86.3%), and more than two-thirds (94/140, 67.1%) of the participants reported that the program helped them lose weight. Significant improvements were observed in fruit and vegetable intake, physical activity, sleep quality, hunger, food cravings, quality of life, and well-being (all P values
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- 2023
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28. Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management.
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Hiba Jebeile, Natalie B Lister, Sol Libesman, Kylie E Hunter, Caitlin M McMaster, Brittany J Johnson, Louise A Baur, Susan J Paxton, Sarah P Garnett, Amy L Ahern, Denise E Wilfley, Sarah Maguire, Amanda Sainsbury, Katharine Steinbeck, Lisa Askie, Caroline Braet, Andrew J Hill, Dasha Nicholls, Rebecca A Jones, Genevieve Dammery, Alicia M Grunseit, Kelly Cooper, Theodore K Kyle, Faith A Heeren, Fiona Quigley, Rachel D Barnes, Melanie K Bean, Kristine Beaulieu, Maxine Bonham, Kerri N Boutelle, Braulio Henrique Magnani Branco, Simona Calugi, Michelle I Cardel, Kelly Carpenter, Hoi Lun Cheng, Riccardo Dalle Grave, Yngvild S Danielsen, Marcelo Demarzo, Aimee Dordevic, Dawn M Eichen, Andrea B Goldschmidt, Anja Hilbert, Katrijn Houben, Mara Lofrano do Prado, Corby K Martin, Anne McTiernan, Janell L Mensinger, Carly Pacanowski, Wagner Luiz do Prado, Sofia M Ramalho, Hollie A Raynor, Elizabeth Rieger, Eric Robinson, Vera Salvo, Nancy E Sherwood, Sharon A Simpson, Hanna F Skjakodegard, Evelyn Smith, Stephanie Partridge, Marian Tanofsky-Kraff, Rachael W Taylor, Annelies Van Eyck, Krista A Varady, Alaina P Vidmar, Victoria Whitelock, Jack Yanovski, Anna L Seidler, and Eating Disorders In weight-related Therapy (EDIT) Collaboration
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Medicine ,Science - Abstract
The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.
- Published
- 2023
- Full Text
- View/download PDF
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