14 results on '"Merk, L"'
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2. Precision electroweak measurements on the Z resonance
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Schael, S, Barate, R, Bruneliere, R, Buskulic, D, Bonis, De, Decamp, I, Ghez, D, Goy, P, Jezequel, C, Lees, S, Lucotte, Jp, Martin, A, Merle, F, Minard, E, Nief, Mn, Odier, Jy, Pietrzyk, P, Trocme, B, Bravo, B, Casado, S, Chmeissani, Mp, Comas, M, Crespo, P, Fernandez, Jm, E, Fernandez, Bosman, Garrido, M, Grauges, L, Juste, E, Martinez, A, Merino, M, Miquel, G, Mir, R, Orteu, Lm, Pacheco, S, Park, A, Perlas, Ic, Riu, J, Ruiz, I, Sanchez, H, Colaleo, F, Creanza, A, D, Filippis, De, N, Palma, De, Iaselli, M, Maggi, G, Nuzzo, M, Ranieri, S, Raso, A, Ruggieri, G, Selvaggi, F, Silvestris, G, Tempesta, L, Tricomi, P, Zito, A, Huang, G, Lin, X, Ouyang, J, Wang, Q, Xie, T, Xu, Y, Xue, R, Zhang, S, Zhang, J, Zhao, L, Abbaneo, W, Bazarko, D, Becker, A, Boix, U, Bird, G, Blucher, F, Bonvicini, E, B, Bright, Thomas, Barklow, P, Buchmuller, T, Cattaneo, O, Cerutti, M, Ciulli, F, Clerbaux, V, Drevermann, B, Forty, H, Frank, Rw, Greening, M, Hagelberg, Tc, Halley, R, Gianotti, Aw, Girone, F, Hansen, M, Harvey, Jb, Jacobsen, J, Hutchcroft, R, Janot, De, Jost, R, Knobloch, B, Kado, J, Lehraus, M, Lazeyras, I, Maley, P, Mato, R, May, P, Moutussi, J, A, Pepe, Altarelli, Ranjard, M, Rolandi, F, Schlatter, L, Schmitt, D, Schneider, B, Tejessy, O, Teubert, W, Tomalin, F, Tournefier, Ir, Veenhof, E, Valassi, R, Wiedenmann, A, Wright, W, Ajaltouni, Ae, Badaud, Z, Chazelle, F, Deschamps, G, Dessagne, O, Falvard, S, Ferdi, A, Fayolle, C, Gay, D, Guicheney, P, Henrard, C, Jousset, P, Michel, J, Monteil, B, Montret, S, Pallin, Jc, Pascolo, D, Perret, Jm, Podlyski, P, Bertelsen, F, Fernley, H, Hansen, T, Hansen, Jd, Hansen, Jr, Kraan, Ph, Lindahl, Ac, Mollerud, A, Nilsson, R, Rensch, Bs, Waananen, B, Daskalakis, A, Kyriakis, G, Markou, A, Simopoulou, C, Siotis, E, Vayaki, I, Zachariadou, A, Blondel, K, Bonneaud, A, Brient, G, Machefert, Jc, Rouge, E, Rumpf, A, Swynghedauw, M, Tanaka, M, Verderi, R, Videau, M, Focardi, H, Parrini, E, Corden, G, Georgiopoulos, M, Antonelli, C, Antonelli, A, Bencivenni, M, Bologna, G, Bossi, G, Campana, F, Capon, P, Chiarella, G, Felici, V, Laurelli, G, Mannocchi, P, Murtas, G, Passalacqua, Gp, Picchi, L, Colrain, P, P, Ten, Have, Hughes, I, Kennedy, Is, Knowles, J, Lynch, Ig, Morton, Jg, Negus, Wt, Oshea, P., Raine, V, Reeves, C, Scarr, P, Smith, Jm, Thompson, K., Turnbull, As, Wasserbaech, Rm, Cavanaugh, S, Dhamotharan, R, Geweniger, S, Hanke, C, Hansper, P, Hepp, G, Kluge, V, Putzer, Ee, Sommer, A, Stenzel, J, Tittel, H, Werner, K, Wunsch, W, Beuselinck, M, Binnie, R, Cameron, Dm, Davies, W, Dornan, G, Goodsir, Pj, Marinelli, S, Martin, N, Nash, Eb, Nowell, J, Rutherford, J, Sedgbeer, Sa, Thompson, Jk, White, Jc, Williams, R, Ghete, Md, Girtler, Vm, Kneringer, P, Kuhn, E, Rudolph, D, G, Bouhova, Thacker, Bowdery, E, Buck, Ck, Clarke, Pg, Ellis, Dp, Finch, G, Foster, Aj, Hughes, F, Jones, G, Rwl, Keemer, Pearson, Nr, Robertson, Mr, Sloan, Na, Smizanska, T, Snow, M, Williams, Sw, van der Aa, Delaere, O, Leibenguth, C, Lemaitre, G, Bauerdick, V, Lat, Blumenschein, U, Van, Gemmeren, Giehl, P, Holldorfer, I, Jakobs, F, Kasemann, K, Kayser, M, Kleinknecht, F, Muller, K, Quast, As, Renk, G, Rohne, B, Sander, E, Schmeling, Hg, Wachsmuth, S, Wanke, H, Zeitnitz, R, Ziegler, C, Aubert, T, Benchouk, Jj, Bonissent, C, Carr, A, Coyle, J, Curtil, P, Ealet, C, Etienne, A, Fouchez, F, Motsch, D, Payre, F, Rousseau, P, Tilquin, D, Talby, A, Thulasides, M, Aleppo, M, Ragusa, M, Buscher, F, David, V, Dietl, A, Ganis, H, Huttmann, G, Lutjens, K, Mannert, G, Manner, C, Moser, W, Settles, Hg, Seywerd, R, Villegas, H, Wolf, M, Azzurri, G, Boucrot, P, Callot, J, Chen, O, Cordier, S, Davier, A, Duflot, M, Grivaz, L, Heusse, Jf, Jacholkowska, P, Diberder, Le, Lefrancois, F, Mutz, J, Schune, Am, Serin, Mh, Veillet, L, Videau, Jj, Zerwas, I, Bagliesi, D, Bettarini, G, Boccali, S, Bozzi, T, Calderini, C, Dellorso, G, Fantechi, R, Ferrante, R, Fidecaro, I, Foa, F, Giammanco, L, Giassi, A, Gregorio, A, Ligabue, A, Lusiani, F, Marrocchesi, PIER SIMONE, Messineo, Ps, Palla, A, Rizzo, F, Sanguinetti, G, Sciaba, G, Sguazzoni, A, Spagnolo, G, Steinberger, P, Tenchini, J, Venturi, R, Vannini, A, Verdini, C, Awunor, Pg, Blair, O, Cowan, Ga, Garcia, Bellido, Green, A, Medcalf, Mg, Misiejuk, T, Strong, A, Teixeira, Dias, Botterill, P, Clifft, Dr, Edgecock, Rw, Edwards, Tr, Haywood, M, Norton, Sj, Ward, Pr, Bloch, Devaux, Boumediene, B, Colas, D, Emery, P, Fabbro, S, Kozanecki, B, Lancon, W, Lemaire, E, Locci, Mc, Perez, E, Rander, P, Renardy, J, Roussarie, Jf, Schuller, A, Schwindling, Jp, Tuchming, J, Vallage, B, Black, B, Dann, Sn, Kim, Jh, Konstantinidis, Hy, Litke, N, Mcneil, Am, Taylor, Ma, Booth, G, Cartwright, Cn, Combley, S, Hodgson, F, Lehto, Pn, Thompson, M, Affholderbach, Lf, Barberio, K, Bohrer, E, Brandt, A, Burkhardt, S, Feigl, H, Grupen, E, Hess, C, Lutters, J, Meinhard, G, H, Minguet, Rodriguez, Mirabito, J, Neugebauer, L, Ngac, E, Prange, A, Rivera, G, Saraiva, F, Schafer, P, Sieler, U, Smolik, U, Stephan, L, Trier, F, Apollonio, H, Borean, M, Bosisio, C, L, Della, Marina, Giannini, R, Gobbo, G, Musolino, B, Pitis, G, He, L, Kim, H, Putz, H, Rothberg, J, Armstrong, J, Bellantoni, Sr, Berkelman, L, Cinabro, K, Conway, D, Cranmer, Js, Elmer, K, Feng, P, Ferguson, Z, Dps, Gao, Gonzalez, Y, Grahl, S, Harton, J, Hayes, Jl, Hu, Oj, Jin, H, Johnson, S, Kile, Rp, Mcnamara, J, Nielsen, Pa, Orejudos, J, Pan, W, Saadi, Y, Scott, Y, Sharma, Ij, Walsh, V, Walsh, Am, Wear, J, J, von Wimmersperg Toeller, Wu, Jh, Wu, J, Wu, Sl, Yamartino, X, Zobernig, Jm, Dissertori, G, Abdallah, G, Abreu, J, Adam, P, Adye, W, Adzic, T, Ajinenko, P, Albrecht, I, Alderweireld, T, Alekseev, T, Alemany, Fernandez, Allmendinger, R, Allport, T, Almehed, Pp, Amaldi, S, Amapane, U, Amato, N, Anashkin, S, Anassontzis, E, Andersson, Eg, Andreazza, P, Andringa, A, Anjos, S, Antilous, N, Apel, P, Arnoud, Wd, Ask, Y, Asman, S, Augustin, B, Augustinus, Je, Baillon, A, Ballestrero, P, Bambade, A, Barao, P, Barbiellini, F, Barbier, G, Bardin, R, Barker, D, Baroncelli, G, Battaglia, A, Baubillier, M, Becks, M, Begalli, Kh, Behrmann, M, Beilliere, A, Belokopytov, P, Belous, Y, K, Ben, Haim, Benekos, E, Benvenuti, N, Berat, A, Berggren, C, Berntzon, M, Bertini, L, Bertrand, D, Besancon, D, Besson, M, Bianchi, N, Bigi, F, Bilenky, M, Bizouard, Ms, Bloch, Ma, Blom, D, Bluj, M, Bonesini, M, Bonivento, M, Boonekamp, W, Booth, M, Psl, Borgland, Borisov, Aw, Bosio, G, Botner, C, Boudinov, O, Bouquet, E, Bourdarios, B, Bowcock, C, Tjv, Boyko, Bozovic, I, Bozzo, I, Bracko, M, Branchini, M, Brenke, P, Brenner, T, Brodet, R, Bruckman, E, Brunet, P, Bugge, Jm, Buran, L, Burgsmueller, T, Buschbeck, T, Buschmann, B, Cabrera, P, Caccia, S, Calvi, M, Rozas, M, Ajc, Camporesi, Canale, T, Canepa, V, Carena, M, Carroll, F, Caso, L, Gimenez, C, Mvc, Castro, Cattai, N, Cavallo, A, Cerruti, F, Chabaud, C, Chapkin, V, Charpentier, M, Chaussard, P, Checchia, L, Chelkov, P, Chen, Ga, Chierici, M, Chliapnikov, R, Chochula, R, Chorowicz, P, Chudoba, V, Chung, J, Cieslik, Su, Collins, K, Colomer, P, Contri, M, Cortina, R, Cosme, E, Cossuti, G, Costa, F, Cowell, Mj, Crawley, Jh, Crennell, Hb, Crepe, D, Crosetti, S, Cuevas, G, Czellar, J, Dhondt, S, Dalmagne, J, Dalmau, B, Damgaard, J, Davenport, G, M, Silva, Da, T, Deghorain, W, Della, Ricca, Delpierre, G, Demaria, P, Angelis, De, Boer, De, W, Brabandere, De, S, Clercq, De, C, Lotto, De, Maria, De, Min, De, Paula, De, Dijkstra, L, Ciaccio, Di, Diodato, Di, Simone, Di, Djannati, A, Dolbeau, A, Doroba, J, Dracos, K, Drees, M, Drees, J, Dris, Ka, Duperrin, M, Durand, A, Ehret, Jd, Eigen, R, Ekelof, G, Ekspong, T, Ellert, G, Elsing, M, Engel, M, Erzen, Jp, Santo, B, Mce, Falk, Fanourakis, E, Fassouliotis, G, Fayot, D, Feindt, J, Fenyuk, M, Fernandez, A, Ferrari, J, Ferrer, P, Ferrer, Ribas, Ferro, E, Fichet, F, Firestone, S, Fischer, A, Flagmeyer, Pa, Foeth, U, Fokitis, H, Fontanelli, E, Franek, F, Frodesen, B, Fruhwirth, Ag, R, Fulda, Quenzer, Fuster, F, Galloni, J, Gamba, A, Gamblin, D, Gandelman, S, Garcia, M, Garcia, C, Gaspar, J, Gaspar, C, Gasparini, M, Gavillet, U, Gazis, P, Gele, E, Gerber, D, Gerdyukov, Jp, Ghodbane, L, Gil, N, Glege, I, Gokieli, F, Golob, R, Gomez, Ceballos, Goncalves, G, Caballero, P, Gopal, Ig, Gorn, G, Gorski, L, Gouz, M, Gracco, Y, Graziani, V, Green, E, Grefrath, C, Grimm, A, Gris, Hj, Grosdidier, P, Grzelak, G, Gunther, K, Guy, M, Haag, J, Hahn, C, Hahn, F, Hallgren, S, Hamacher, A, Hamilton, K, Hansen, K, Harris, J, Haug, Fj, Hauler, S, Hedberg, F, Heising, V, Hennecke, S, Henriques, M, Hernandez, R, Herquet, Jj, Herr, P, Hessing, H, Heuser, Tl, Higon, Jm, Hoffman, E, Holmgren, J, Holt, So, Holthuizen, Pj, Hoorelbeke, D, Houlden, S, Hrubec, Ma, Huber, J, Huet, M, Hughes, K, Hultqvist, Gj, Jackson, K, Jacobsson, Jn, Jalocha, R, Janik, P, Jarlskog, R, Jarlskog, C, Jarry, G, Jean, Marie, Jeans, B, Johansson, D, Johansson, Ek, Jonsson, Pd, Joram, P, Juillot, C, Jungermann, P, Kapusta, L, Karafasoulis, F, Katsanevas, K, Katsoufis, S, Keranen, E, Kernel, R, Kersevan, G, Kerzel, Bp, Khomenko, U, Khovanski, Ba, Kiiskinen, Nn, King, A, Kinvig, Bt, Kjaer, A, Klapp, Nj, Klein, O, Kluit, H, Knoblauch, P, Kokkinias, D, Konopliannikov, P, Koratzinos, A, Kostioukhine, M, Kourkoumelis, V, Kouznetsov, C, Krammer, O, Kreuter, M, Kriznic, C, Krstic, E, Krumstein, J, Kubinec, Z, Kucewicz, P, Kucharczyk, W, Kurowska, M, Kurvinen, J, Lamsa, K, Lanceri, J, Lane, L, Langefeld, Dw, Lapin, P, Laugier, V, Lauhakangas, Jp, Leder, R, Ledroit, G, Lefebure, F, Leinonen, V, Leisos, L, Leitner, A, Lemonne, R, Lenzen, J, Lepeltier, G, Lesiak, V, Lethuillier, T, Libby, M, Liebig, J, Liko, W, Lipniacka, D, Lippi, A, Loerstad, I, Lokajicek, B, Loken, M, Lopes, Jg, Lopez, Jh, Lopez, Femandez, Loukas, R, Lutz, D, Lyons, P, Macnaughton, L, Mahon, J, Maio, Jr, Malek, A, Malmgren, A, Tgm, Maltezos, Malychev, S, Mandl, V, Marco, F, Marco, J, Marechal, R, Margoni, B, Marin, M, Mariotti, Jc, Markou, C, Martinez, Rivero, Martinez, Vidal, Garcia, F, Smi, Masik, Mastroyiannopoulos, J, Matorras, N, Matteuzzi, F, Matthiae, C, Mazik, G, Mazzucato, J, Mazzucato, F, Mccubbin, M, Mckay, M, Mcnulty, R, Meroni, R, Meyer, C, Miagkov, Wt, Migliore, A, Mitaroff, E, Mjoernmark, W, Moa, U, Moch, T, Moeller, M, Moenig, R, Monge, K, Montenegro, R, Moraes, J, Moreau, D, Moreno, X, Morettini, S, Morton, P, Mueller, G, Muenich, U, Mulders, K, Mulet, Marquis, Mundim, C, Muresan, L, Murray, R, Muryn, W, Myatt, B, Myklebust, G, Naraghi, T, Nassiakou, F, Navarria, M, Navas, F, Nawrocki, S, Negri, K, Neufeld, P, Neumann, N, Neumeister, W, Nicolaidou, N, Nielsen, R, Nieuwenhuizen, Bs, Niezurawski, M, Nikolaenko, P, Nikolenko, V, Nomokonov, M, Normand, V, Nygren, A, Oblakowska, Mucha, Obraztsov, A, Olshevski, V, Onofre, A, Orava, A, Orazi, R, Osterberg, G, Ouraou, K, Oyanguren, A, Paganini, A, Paganoni, P, Paiano, M, Pain, S, Paiva, R, Palacios, R, Palka, Jp, Papadopoulou, H, Papageorgiou, Td, Pape, K, Parkes, L, Parodi, C., Parzefall, F, Passeri, U, Passon, A, Pavel, O, Pegoraro, T, Peralta, M, Perepelitsa, L, Pernicka, V, Perrotta, M, Petridou, A, Petrolini, C, Philips, A, Piana, Ht, Piedra, G, Pieri, J, Pierre, L, Pimenta, F, Piotto, M, Podobnik, E, Poireau, T, Pol, V, Polok, Me, Polycarpo, G, Poropat, E, Pozdniakov, P, Privitera, V, Pukhaeva, R, Pullia, N, Radojicic, A, Ragazzi, D, Rahmani, S, Rakoczy, H, Rames, D, Ramler, J, Ratoff, L, Read, Pn, Rebecchi, A, Redaelli, P, Regler, Ng, Rehn, M, Reid, J, Reinhardt, D, Renton, R, Resvanis, P, Richard, Lk, Ridky, F, Rinaudo, J, Ripp, Baudot, Rivero, I, Rodriguez, M, Rohne, D, Romero, O, Ronchese, A, Rosenberg, P, Rosinsky, Ei, Roudeau, P, Rovelli, R, Royon, T, Ruhlmann, Kleider, Ruiz, V, Ryabtchikov, A, Saarikko, D, Sacquin, H, Sadovsky, Y, Sajot, A, Salmi, G, Salt, L, Sampsonidis, J, Sannino, D, Savoy, Navarro, Scheidle, A, Schneider, T, Schwemling, H, Schwering, P, Schwickerath, B, Schyns, U, Mae, Scuri, Seager, F, Sedykh, P, Segar, Y, Seibert, A, Sekulin, N, Shellard, R, Sheridan, Rc, Siebel, A, Silvestre, M, Simard, R, Simonetto, L, Sisakian, F, Skaali, A, Smadja, Tb, Smirnov, G, Smirnova, N, Smith, O, Sokolov, Gr, Sopczak, A, Sosnowski, A, Spassov, R, Spiriti, T, Sponholz, E, Squarcia, P, Stampfer, S, Stanescu, D, Stanic, C, Stanitzki, S, Stapnes, M, Stevenson, S, Stocchi, K, Strauss, A, Strub, J, Stugu, R, Szczekowski, B, Szeptycka, M, Szumlak, M, Tabarelli, T, Taffard, T, Tegenfeldt, Ac, Terranova, F, Thomas, F, Timmermans, J, Tinti, J, Tkatchev, N, Tobin, L, Todorov, M, Todorovova, T, Toet, S, Tomaradze, Dz, Tome, A, Tonazzo, B, Tortora, A, Tortosa, L, Transtromer, P, Travnicek, G, Treille, P, Tristram, D, Trochimczuk, G, Trombini, M, Troncon, A, Tsirou, C, Turluer, A, Tyapkin, Ml, Tyapkin, Ia, Tzamarias, P, Ullaland, S, Uvarov, O, Valenti, V, Vallazza, G, Vander, Velde, Van, Apeldoorn, Van, Dam, Van den Boeck, Van, Doninck, Van, Eldik, Van, Lysebetten, Van, Remortel, Van, Vulpen, Vassilopoulos, I, Vegni, N, Velos, G, Ventura, F, Venus, L, Verbeure, W, Verdier, F, Verlato, P, Vertogradov, M, Verzi, Ls, Vilanova, V, Vitale, D, Vlasov, L, Vodopyanov, E, Vollmer, As, Voulgaris, C, Vrba, G, Wahlen, V, Walck, H, Washbrook, C, Weiser, Aj, Wetherell, C, Wicke, Am, Wickens, D, Wilkinson, J, Winter, G, Witek, M, Wlodek, M, Yi, T, Yushchenko, J, Zaitsev, O, Zalewska, A, Zalewski, A, Zavrtanik, P, Zevgolatakos, D, Zhuravlov, E, Zimin, V, Zintchenko, Ni, Zoller, A, Zucchelli, P, Zumerle, Gc, Zupan, G, Acciarri, M, Achard, M, Adriani, P, O, Aguilar, Benitez, Alcaraz, M, Alemanni, J, Allaby, G, Aloisio, J, Alviggi, A, Ambrosi, Mg, Anderhub, G, Andreev, H, Angelescu, Vp, Anselmo, T, Arefiev, F, Azemoon, A, Aziz, T, Bagnaia, T, Bajo, P, Baksay, A, Baksay, G, Balandras, L, Baldew, A, Ball, Sv, Banerjee, Rc, Barczyk, S, Barillere, A, Barone, R, Bartalini, L, Basile, P, Batalova, M, Battiston, N, Bay, R, Becattini, A, Behner, F, Bellucci, F, Berbeco, L, Berdugo, R, Berges, J, Bertucci, P, Betev, B, Bhattacharya, Bl, Biasini, S, Biglietti, M, Biland, M, Blaising, A, Blyth, Jj, Bobbink, Sc, Bohm, Bj, Boldizsar, A, Borgia, L, Bottai, B, Bourilkov, S, Bourquin, D, Braccini, M, Branson, S, Brigljevic, Jg, Brochu, V, Brock, F, Buffini, Ic, Buijs, A, Burger, A, Burger, Jd, Button, Wj, Cai, A, Campanelli, Xd, Capell, M, Romeo, M, Carlino, Gc, Cartacci, G, Casaus, A, Castellini, J, Cavallari, G, Cavallo, E, Cecchi, N, Cerrada, C, Cesaroni, M, Chamizo, F, Chang, M, Chaturvedi, Yh, Chemarin, Uk, Chen, M, Chen, A, Chen, G, Chen, Gm, Chen, Hf, Chiefari, Hs, Cifarelli, G, Cindolo, L, Civinini, F, Clare, C, Clare, I, Coignet, R, Colijn, G, Colino, Ap, Costantini, N, Cotorobai, S, Cozzoni, F, de la Cruz, Csilling, B, Cucciarelli, A, Dai, S, Van, Dalen, Dalessandro, Ja, Asmundis, De, Debreczeni, R, Deglon, J, Degre, P, Dehmelt, P, Deiters, K, Della, Volpe, Delmeire, D, Denes, E, Denotaristefani, P, F, Salvo, De, Diemoz, A, Dierckxsens, M, Van, Dierendonck, Lodovico, Di, Dionisi, F, Dittmar, C, Dominguez, M, Doria, A, Dova, A, Duchesneau, Mt, Dufournaud, D, Duda, D, Duinker, M, Duran, P, Dutta, I, Echenard, S, Eline, B, Hage, El, Mamouni, El, Engler, H, Eppling, A, Erne, Fj, Extermann, Fc, Fabre, P, Faccini, M, Falagan, R, Falciano, Ma, Favara, S, Fay, A, Fedin, J, Felcini, O, Ferguson, M, Ferroni, T, Fesefeldt, F, Fiandrini, H, Field, E, Filthaut, Jh, Fisher, F, Fisher, Ph, Fisk, W, Forconi, I, Fredj, G, Freudenreich, L, Furetta, K, Galaktionov, C, Ganguli, Y, Garcia, Abia, Gataullin, P, Gau, M, Gentile, Ss, Gheordanescu, S, Giagu, N, Gong, S, Grenier, Zf, Grimm, G, Gruenewald, O, Guida, Mw, Van, Gulik, Van, Gupta, Gurtu, Vk, Gutay, A, Haas, Lj, Hasan, D, Hatzifotiadou, A, Hebbeker, D, Herve, T, Hidas, A, Hirschfelder, P, Hofer, J, Hohlmann, H, Holzner, M, Hoorani, G, Hou, H, Lashvili, Sr, Innocente, I, Jin, V, Jindal, Bn, Jones, P, Dejong, Lw, Josa, Mutuberria, Khan, I, Kaur, Ra, Kienzle, Focacci, Kim, Mn, Kim, D, Kirkby, Jk, Kiss, J, Kittel, D, Klimentov, W, Konig, A, Koffeman, Ac, Kopal, E, Kopp, M, 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Thaler, Fe, Thom, Jj, Trandafir, J, Turk, Ai, Usher, Jd, Vavra, T, Vella, J, Venuti, E, Verdier, Jp, Wagner, R, Waite, Sr, Walston, Ap, Wang, S, Watts, J, Weidemann, Sj, Weiss, Aw, Whitaker, Er, White, Js, Wickens, Sl, Williams, Fj, Williams, Da, Williams, Dc, Willocq, Sh, Wilson, S, Wisniewski, Rj, Wittlin, Wj, Woods, Jl, Word, M, Wright, Gb, Wyss, Tr, Yamamoto, J, Yang, Rk, Yashima, Xq, Yellin, J, Young, Sj, Yuta, Cc, Zapalac, H, Zdarko, G, Zeitlin, Rw, Zhou, C, Blondel, Alain, Schael, S, Barate, R, Bruneliere, R, Spagnolo, Stefania Antonia, S., Schael, Aloisio, Alberto, Alviggi, Mariagrazia, Canale, Vincenzo, Chiefari, Giovanni, DELLA VOLPE, Domenico, Merola, Leonardo, Napolitano, Marco, Patricelli, Sergio, Sciacca, Crisostomo, Lista, Luca, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Théorique et Astroparticules (LPTA), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches Subatomiques (IReS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Cancéropôle du Grand Est-Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF (institution))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ALEPH, DELPHI, L3, OPAL, SLD, BARBIELLINI AMIDEI, Guido, Bosisio, Luciano, DELLA RICCA, Giuseppe, Giannini, Gianrossano, Gregorio, Anna, Lanceri, Livio, Poropat, Paolo, Vitale, Lorenzo, Buskulic, D, De Bonis, I, Decamp, D, Ghez, P, Goy, C, Jezequel, S, Lees, J, Lucotte, A, Martin, F, Merle, E, Minard, M, Nief, J, Odier, P, Pietrzyk, B, Trocme, B, Bravo, S, Casado, M, Chmeissani, M, Comas, P, Crespo, J, Fernandez, E, Fernandez Bosman, M, Garrido, L, Grauges, E, Juste, A, Martinez, M, Merino, G, Miquel, R, Mir, L, Orteu, S, Pacheco, A, Park, I, Perlas, J, Riu, I, Ruiz, H, Sanchez, F, Colaleo, A, Creanza, D, De Filippis, N, De Palma, M, Iaselli, G, Maggi, G, Maggi, M, Nuzzo, S, Ranieri, A, Raso, G, Ruggieri, F, Selvaggi, G, Silvestris, L, Tempesta, P, Tricomi, A, Zito, G, Huang, X, Lin, J, Ouyang, Q, Wang, T, Xie, Y, Xu, R, Xue, S, Zhang, J, Zhang, L, Zhao, W, Abbaneo, D, Bazarko, A, Becker, U, Boix, G, Bird, F, Blucher, E, Bonvicini, B, Bright Thomas, P, Barklow, T, Buchmuller, O, Cattaneo, M, Cerutti, F, Ciulli, V, Clerbaux, B, Drevermann, H, Forty, R, Frank, M, Greening, T, Hagelberg, R, Halley, A, Gianotti, F, Girone, M, Hansen, J, Harvey, J, Jacobsen, R, Hutchcroft, D, Janot, R, Jost, B, Knobloch, J, Kado, M, Lehraus, I, Lazeyras, P, Maley, R, Mato, P, May, J, Moutussi, A, Pepe Altarelli, M, Ranjard, F, Rolandi, L, Schlatter, D, Schmitt, B, Schneider, O, Tejessy, W, Teubert, F, Tomalin, I, Tournefier, E, Veenhof, R, Valassi, A, Wiedenmann, W, Wright, A, Ajaltouni, Z, Badaud, F, Chazelle, G, Deschamps, O, Dessagne, S, Falvard, A, Ferdi, C, Fayolle, D, Gay, P, Guicheney, C, Henrard, P, Jousset, J, Michel, B, Monteil, S, Montret, J, Pallin, D, Pascolo, J, Perret, P, Podlyski, F, Bertelsen, H, Fernley, T, Hansen, P, Kraan, A, Lindahl, A, Mollerud, R, Nilsson, B, Rensch, B, Waananen, A, Daskalakis, G, Kyriakis, A, Markou, C, Simopoulou, E, Siotis, I, Vayaki, A, Zachariadou, K, Blondel, A, Bonneaud, G, Brient, J, Machefert, E, Rouge, A, Rumpf, M, Swynghedauw, M, Tanaka, R, Verderi, M, Videau, H, Focardi, E, Parrini, G, Corden, M, Georgiopoulos, C, Antonelli, A, Antonelli, M, Bencivenni, G, Bologna, G, Bossi, F, Campana, P, Capon, G, Chiarella, V, Felici, G, Laurelli, P, Mannocchi, G, Murtas, G, Passalacqua, L, Picchi, P, Colrain, P, Ten Have, I, Hughes, I, Kennedy, J, Knowles, I, Lynch, J, Morton, W, Negus, P, O'Shea, V, Raine, C, Reeves, P, Scarr, J, Smith, K, Thompson, A, Turnbull, R, Wasserbaech, S, Cavanaugh, R, Dhamotharan, S, Geweniger, C, Hanke, P, Hansper, G, Hepp, V, Kluge, E, Putzer, A, Sommer, J, Stenzel, H, Tittel, K, Werner, W, Wunsch, M, Beuselinck, R, Binnie, D, Cameron, W, Davies, G, Dornan, P, Goodsir, S, Marinelli, N, Martin, E, Nash, J, Nowell, J, Rutherford, S, Sedgbeer, J, Thompson, J, White, R, Williams, M, Ghete, V, Girtler, P, Kneringer, E, Kuhn, D, Rudolph, G, Bouhova Thacker, E, Bowdery, C, Buck, P, Clarke, D, Ellis, G, Finch, A, Foster, F, Hughes, G, Jones, R, Keemer, N, Pearson, M, Robertson, N, Sloan, T, Smizanska, M, Snow, S, Van Der Aa, O, Delaere, C, Leibenguth, G, Lemaitre, V, Bauerdick, L, Blumenschein, U, Van Gemmeren, P, Giehl, I, Holldorfer, F, Jakobs, K, Kasemann, M, Kayser, F, Kleinknecht, K, Muller, A, Quast, G, Renk, B, Rohne, E, Sander, H, Schmeling, S, Wachsmuth, H, Wanke, R, Zeitnitz, C, Ziegler, T, Aubert, J, Benchouk, C, Bonissent, A, Carr, J, 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Vandalen, Gj, Virtue, Cj, Vokurka, Eh, Vollmer, Cf, Wagner, Dl, Walker, Jp, Ward, Cp, Ward, Dr, Watkins, Pm, Watson, At, Watson, Nk, Whalley, Ma, Wilson, Ja, Wilson, Gw, Winterer, Vh, Wood, Nc, Wyatt, Tr, Zorn, Gt, Allen, Nj, Ash, Ww, Baird, Kg, Band, Hr, Barakat, Mb, Baranko, Gj, Barklow, Tl, Bashindzhagian, Gl, Bauer, Jm, Bazarko, Ao, Benvenuti, Ac, Bilei, Gm, Bower, Gr, Brau, Je, Bugg, Wm, Burnett, Th, Burrows, Pn, Caldwell, Do, Chadwick, Gb, Cohn, Ho, Coller, Ja, Convery, Mr, Cowan, Rf, Coyle, Pa, Coyne, Dg, Damerell, Cj, de Groot, N, de Sangro, R, Dervan, Pj, Dong, Dn, Du, Pyc, Eisenstein, Bi, Fernandez, Jp, Fero, Mj, Friedman, Ji, Garwin, El, Hallewell, Gd, Hart, El, Hitlin, Dg, Huffer, Me, Hughes, Ew, Izen, Jm, Jackson, Dj, Jaros, Ja, Jiang, Zy, Johnson, Jr, Johnson, Ra, Kamyshkov, Ya, Kang, Hj, Kelsey, Mh, Kendall, Hw, Kim, Yd, Krishna, Nm, Labs, Jf, Lauber, Ja, Leith, Dwg, Liu, Mx, Lynch, Hl, Markiewicz, Tw, Mcgowan, Jf, Mckemey, Ak, Meadows, Bt, Mockett, Pm, Moffeit, Kc, 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MCGOWAN, A.K. MCKEMEY, B.T. MEADOWS, R. MESSNER, P.M. MOCKETT, K.C. MOFFEIT, T.B. MOORE, M. MORII, B. MOURS, D. MULLER, G. MUELLER, V. MURZIN, T. NAGAMINE, S. NARITA, U. NAUENBERG, H. NEAL, G. NESOM, M. NUSSBAUM, Y. OHNISHI, N. OISHI, D. ONOPRIENKO, L.S. OSBORNE, R.S. PANVINI, C.H.PARK, H. PARK, T.J. PAVEL, I. PERUZZI, L. PESCARA, M. PICCOLO, L. PIEMONTESE, E. PIERONI, K.T. PITTS, R.J. PLANO, R. PREPOST, C.Y. PRESCOTT, G. PUNKAR, J. QUIGLEY, B.N. RATCLIFF, K. REEVES, T.W. REEVES, J. REIDY, P.L. REINERTSEN, P.E. RENSING, L.S. ROCHESTER, J.E. ROTHBERG, P.C. ROWSON, J.J. RUSSELL, O.H. SAXTON, T. SCHALK, R.H. SCHINDLER, U. SCHNEEKLOTH, B.A. SCHUMM, J. SCHWIENING, A. SEIDEN, S. SEN, V.V. SERBO, L. SERVOLI, M.H. SHAEVITZ, J.T. SHANK, G. SHAPIRO, D.J. SHERDEN, K.D. SHMAKOV, C. SIMOPOULOS, N.B. SINEV, S.R. SMITH, M.B. SMY, J.A. SNYDER, M.D. SOKOLOFF, H. STAENGLE, A. STAHL, P. STAMER, H. STEINER, R. STEINER, M.G. STRAUSS, D. SU, F. SUEKANE, A. SUGIYAMA, A. SUZUKI, S. SUZUKI, M. SWARTZ, A. SZUMILO, T. TAKAHASHI, F.E. TAYLOR, J.J. THALER, J. THOM, E. TORRENCE, A.I. TRANDAFIR, J.D. TURK, T. USHER, J. VA VRA, C. VANNINI, E. VELLA, J.P. VENUTI, R. VERDIER, P.G. VERDINI, D.L. WAGNER, S.R. WAGNER, A.P. WAITE, S. WALSTON, J. WANG, S.J. WATTS, A.W. WEIDEMANN, E.R. WEISS, J.S. WHITAKER, S.L. WHITE, F.J. WICKENS, D.A. WILLIAMS, D.C. WILLIAMS, S.H. WILLIAMS, S. WILLOCQ, R.J. WILSON, W.J. WISNIEWSKI, J.L. WITTLIN, M. WOODS, G.B. WORD, T.R. WRIGHT, J. WYSS, R.K. YAMAMOTO, J.M. YAMARTINO, X.Q. YANG, J. YASHIMA, S.J. YELLIN, C.C.YOUNG, H.YUTA, G. ZAPALAC, R.W. ZDARKO, C. ZEITLIN, J. ZHOU, Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), GRUNEVALD M, NEWALD M, SCHAEL S, BARATE R, BRUNELIE, RE R, BUSKULIC D, DE BONIS I, DECAMP D, GHEZ P, GOY C, JE, ZE, QUEL S, LEES J, LUCOTTE A, MARTIN M, MERLE E, MINARD M, NIEF J, ODIER P, PIETRZYK B, TROCME, BRAVO S, CASADO MP, CHMEISSANI M, COMAS P, CRESPO JM, FERNANDEZ E, FERNANDEZ-BOSMAN M, GARRIDO L, GRAUGES E, JUSTE A, MARTINEZ M, MERINO G, MIQUEL R, MIR LM, ORTEU S, PACHECO A, PARK IC, PERLAS J, RIU I, RUIZ H, SANCHEZ F, COLALEO A, CREANZA D, DE FILIPPIS N, DE PALMA M, IASELLI G, MAGGI G, MAGGI M, NUZZO S, RANIERI, A, RASO, G, RUGGIERI F, SELVAGGI, G, SILVESTRIS L, TEMPESTA P, TRICOMI A, ZITO G, HUANG X, LIN J, OUYANG Q, WANG T, XIE Y, XU R, XUE S, ZHANG J, ZHANG L, ZHAO W, ABBANEO D, BAZARKO A, BECKER U, BOIX G, BIRD F, BLUCHER E, BONVICINI B, BRIGHT-THOMAS P, BARKLOW T, BUCHMU, LLER O, CATTANEO M, CERUTTI F, CIULLI V, CLERBAUX B, DREVERMANN H, FORTY RW, FRANK M, GREENING TC, HAGELBERG R, HALLEY AW, GIANOTTI F, GIRONE M, HANSEN JB, HARVEY J, JACOBSEN J, HUTCHCROFT DE, JANOT P, JOST B, KNOBLOCH J, KADO M, LEHRAUS I, LAZEYRAS P, and MALEY P
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Top quark ,FORWARD-BACKWARD ASYMMETRY ,PARTICLE PHYSICS ,LARGE ELECTRON POSITRON COLLIDER ,ALEPH ,DELPHI ,L3 ,OPAL ,General Physics and Astronomy ,01 natural sciences ,7. Clean energy ,High Energy Physics - Experiment ,Settore FIS/04 - Fisica Nucleare e Subnucleare ,High Energy Physics - Experiment (hep-ex) ,High Energy Physics - Phenomenology (hep-ph) ,electron-positron physics ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,Electroweak interaction ,Physics ,Quantum chromodynamics ,Electron–positron physics ,Electroweak interactions ,Decays of heavy intermediate gauge bosons ,Fermion–antifermion production ,Precision measurements at the Z resonance ,Tests of the Standard Model ,Radiative corrections ,Effective coupling constants ,Neutral weak current ,Z boson ,W boson ,Higgs boson ,Particle physics - Experiment ,Settore FIS/01 - Fisica Sperimentale ,FERMION-PAIR PRODUCTION ,HADRONIC-Z-DECAYS ,TOP-QUARK MASS ,ANGLE BHABHA SCATTERING ,W-BOSON MASS ,CROSS-SECTION ASYMMETRY ,Z-LINE-SHAPE ,SEMILEPTONIC BRANCHING RATIOS ,CARLO EVENT GENERATOR ,decays of heavy intermediate gauge bosons ,effective coupling constants ,electroweak interactions ,fermion-antifermion production ,higgs boson ,neutral weak current ,precision measurements at the z resonance ,radiative corrections ,tests of the standard model ,top quark ,w boson ,z boson ,Radiative correction ,High Energy Physics - Phenomenology ,FIS/01 - FISICA SPERIMENTALE ,Física nuclear ,Neutrino ,Particle physics ,FOS: Physical sciences ,ddc:500.2 ,Elementary particle physics ,LEP ,electroweak ,Decays of heavy intermediate gauge boson ,Effective coupling constant ,Partícules (Física nuclear) ,Standard Model ,electroweak theory, Z boson, DELPHI, ALEPH, OPAL, L3 ,0103 physical sciences ,010306 general physics ,Coupling constant ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,Fermion ,FORWARD-BACKWARD ASYMMETRY, FERMION-PAIR PRODUCTION, HADRONIC-Z-DECAYS, TOP-QUARK MASS, ANGLE BHABHA SCATTERING, W-BOSON MASS, CROSS-SECTION ASYMMETRY, Z-LINE-SHAPE, SEMILEPTONIC BRANCHING RATIOS, CARLO EVENT GENERATOR ,[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph] ,Experimental High Energy Physics ,Electron–positron physic ,High Energy Physics::Experiment ,FIS/04 - FISICA NUCLEARE E SUBNUCLEARE - Abstract
We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLD experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, $\MZ$ and $\GZ$, and its couplings to fermions, for example the $\rho$ parameter and the effective electroweak mixing angle, are precisely measured. The number of light neutrino species is determined to be 2.9840+/-0.0082. The results are compared to the predictions of the Standard Model. Electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its Standard Model expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the masses of the top quark and the W Boson are predicted. These indirect constraints are compared to the direct measurements, providing a stringent test of the Standard Model. Using in addition the direct measurements of $\Mt$ and $\MW$, the mass of the as yet unobserved Standard Model Higgs boson is predicted., Comment: 302 pages, v2: minor corrections and updates of references. Accepted for publication by Physics Reports, v3: further small corrections and journal version
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- 2006
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3. Monitoring of primary health care services: an example from western Uganda.
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Kipp, W, Kielmann, A A, Kwered, E, Merk, L G, and Rubaale, T
- Abstract
Results from baseline and follow-up surveys of the Basic Health Services Program in Kabarole District, Western Uganda carried out in 1989 and 1991 are presented. Indicators in relation to management capability, infrastructure, levels of basic knowledge and skills of health staff, community involvement and utilization of health services were measured. Subjectivity of the data collection was minimized through use of a randomized study design, and external supervision. Comparability of results between the two surveys was assured by employing the same rapid assessment methodology, using a fixed set of indicators. The results suggest a marked improvement of the health services in Kabarole district since implementation of specific project activities and in direct response to action taken following review of information from the original survey work. Overall, it is felt that this particular method of project monitoring, and using the specific method, Systems' Analysis, generates data particularly useful to national governments and other health organizations. [ABSTRACT FROM AUTHOR]
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- 1994
4. Vergleichende Untersuchungen zum Einfluß von konstanter und gestaffelter Energieversorgung in der Gravidität auf einige Reproduktionskriterien bei Sauen.
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Kirchgessner, M. and Merk, L.
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- 1984
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5. Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis.
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Merk L, Regel K, Eckhardt H, Evers M, El-Ayoubi A, Mittelbronn M, Krüger M, Gérardy JJ, Mack AF, and Naumann U
- Abstract
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. GBM displays excessive and unfunctional vascularization which may, among others, be a reason for its devastating prognosis. Pericytes have been identified as the major component of the irregular vessel structure in GBM. In vitro data suggest an epithelial-to-mesenchymal transition (EMT)-like activation of glioma-associated pericytes, stimulated by GBM-secreted TGF-β, to be involved in the formation of a chaotic and dysfunctional tumor vasculature. This study investigated whether TGF-β impacts the function of vessel associated mural cells (VAMCs) in vivo via the induction of the EMT transcription factor SLUG and whether this is associated with the development of GBM-associated vascular abnormalities. Upon preventing the TGF-β-/SLUG-mediated EMT induction in VAMCs, the number of PDGFRβ and αSMA positive cells was significantly reduced, regardless of whether TGF-β secretion by GBM cells was blocked or whether SLUG was specifically knocked out in VAMCs. The reduced amount of PDGFRβ
+ or αSMA+ cells observed under those conditions correlated with a lower vessel density and fewer vascular abnormalities. Our data provide evidence that the SLUG-mediated modulation of VAMC activity is induced by GBM-secreted TGF-β¬ and that activated VAMCs are key contributors in neo-angiogenic processes. We suggest that a pathologically altered activation of GA-Peris in the tumor microenvironment is responsible for the unstructured tumor vasculature. There is emerging evidence that vessel normalization alleviates tumor hypoxia, reduces tumor-associated edema and improves drug delivery. Therefore, avoiding the generation of an unstructured and non-functional tumor vasculature during tumor recurrence might be a promising treatment approach for GBM and identifies pericytes as a potential novel therapeutic target., Competing Interests: The authors declare no conflicts of interest. All coauthors have reviewed and approved the contents of the manuscript and that the requirements for authorship have been met.- Published
- 2024
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6. Development of an optimized, non-stem cell line for intranasal delivery of therapeutic cargo to the central nervous system.
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El-Ayoubi A, Arakelyan A, Klawitter M, Merk L, Hakobyan S, Gonzalez-Menendez I, Quintanilla Fend L, Holm PS, Mikulits W, Schwab M, Danielyan L, and Naumann U
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- Mice, Humans, Animals, Administration, Intranasal, Cell Line, Central Nervous System metabolism, Thymidine Kinase genetics, Thymidine Kinase metabolism, Thymidine Kinase therapeutic use, Antiviral Agents, Genetic Therapy
- Abstract
Neural stem cells (NSCs) are considered to be valuable candidates for delivering a variety of anti-cancer agents, including oncolytic viruses, to brain tumors. However, owing to the previously reported tumorigenic potential of NSC cell lines after intranasal administration (INA), here we identified the human hepatic stellate cell line LX-2 as a cell type capable of longer resistance to replication of oncolytic adenoviruses (OAVs) as a therapeutic cargo, and that is non-tumorigenic after INA. Our data show that LX-2 cells can longer withstand the OAV XVir-N-31 replication and oncolysis than NSCs. By selecting the highly migratory cell population out of LX-2, an offspring cell line with a higher and more stable capability to migrate was generated. Additionally, as a safety backup, we applied genomic herpes simplex virus thymidine kinase (HSV-TK) integration into LX-2, leading to high vulnerability to ganciclovir (GCV). Histopathological analyses confirmed the absence of neoplasia in the respiratory tracts and brains of immuno-compromised mice 3 months after INA of LX-2 cells. Our data suggest that LX-2 is a novel, robust, and safe cell line for delivering anti-cancer and other therapeutic agents to the brain., (© 2023 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.)
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- 2024
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7. A parents' perspective on the pediatric intensive care unit: our family's journey.
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Merk L and Merk R
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- Child, Preschool, Humans, Male, Nursing Staff, Hospital, Organizational Policy, Quality of Health Care, Visitors to Patients, Workforce, Intensive Care Units, Pediatric organization & administration, Parents, Professional-Family Relations
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The pediatric intensive care unit (PICU) can be an intimidating and frightening place for parents and family members of critically ill children. Most parents experience a loss of control and feelings of utter helplessness. Many PICUs are working with family members to improve the quality of care provided through patient- and family-centered care, which is in fact 1 of the 6 tenets of the Institute of Medicine's definition of quality health care. However, as highlighted by the tragic and very personal experience described by one family, PICUs can and should be doing more to improve the patient and family experience., (Copyright © 2013 Elsevier Inc. All rights reserved.)
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- 2013
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8. Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin.
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Barger JF, Gallo CA, Torni KA, Merk L, Seibel WL, Nelson S, and Plas DR
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- Animals, Caspase 3 metabolism, Cell Line, Cell Membrane drug effects, Cell Survival drug effects, Dose-Response Relationship, Drug, Drug Discovery, Drug Screening Assays, Antitumor methods, Mice, Oxazines, Phosphatidylinositol 3-Kinases metabolism, Proto-Oncogene Proteins c-akt antagonists & inhibitors, Signal Transduction drug effects, Xanthenes, bcl-X Protein genetics, Antineoplastic Agents pharmacology, Apoptosis drug effects, High-Throughput Screening Assays, Proto-Oncogene Proteins c-akt metabolism, Sirolimus pharmacology, bcl-X Protein metabolism
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We performed a high-throughput screen to identify compounds with a selective ability to induce apoptosis in Akt-expressing cells without disrupting Bcl-xL-dependent survival. Results showed that a screening strategy based on Alamar Blue underrepresented the viability of Bcl-xL-expressing cells relative to Akt-expressing cells, possibly due to metabolic differences between the two cell survival programs. Using an alternative screen based on plasma membrane integrity, we identified several compounds that target Akt-dependent survival without toxic effect to Bcl-xL-dependent survival. These compounds enhanced the cytotoxic potential of rapamycin, a chemotherapeutic that inhibits survival signaling downstream of Akt. The results demonstrate a screening method and the subsequent identification of two compounds with selective activity in counteracting Akt-dependent cell survival.
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- 2010
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9. Ammonium transport in the colonic crypt cell line, T84: role for Rhesus glycoproteins and NKCC1.
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Worrell RT, Merk L, and Matthews JB
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- Adenosine Triphosphatases metabolism, Biological Transport, Active physiology, Cell Line, Cyclic AMP pharmacology, DNA, Complementary genetics, Humans, Hydrogen-Ion Concentration, Methylamines metabolism, Plasmids genetics, Reverse Transcriptase Polymerase Chain Reaction, Rubidium Radioisotopes, Sodium-Potassium-Exchanging ATPase metabolism, Solute Carrier Family 12, Member 2, Blood Proteins physiology, Colon cytology, Colon metabolism, Membrane Glycoproteins physiology, Quaternary Ammonium Compounds metabolism, Sodium-Potassium-Chloride Symporters physiology
- Abstract
Although colonic lumen NH(4)(+) levels are high, 15-44 mM normal range in humans, relatively few studies have addressed the transport mechanisms for NH(4)(+). More extensive studies have elucidated the transport of NH(4)(+) in the kidney collecting duct, which involves a number of transporter processes also present in the distal colon. Similar to NH(4)(+) secretion in the renal collecting duct, we show that the distal colon secretory model, T84 cell line, has the capacity to secrete NH(4)(+) and maintain an apical-to-basolateral NH(4)(+) gradient. NH(4)(+) transport in the secretory direction was supported by basolateral NH(4)(+) loading on NKCC1, Na(+)-K(+)-ATPase, and the NH(4)(+) transporter, RhBG. NH(4)(+) was transported on NKCC1 in T84 cells nearly as well as K(+) as determined by bumetanide-sensitive (86)Rb-uptake. (86)Rb-uptake and ouabain-sensitive current measurement indicated that NH(4)(+) is transported by Na(+)-K(+)-ATPase in these cells to an equal extent as K(+). T84 cells expressed mRNA for the basolateral NH(4)(+) transporter RhBG and the apical NH(4)(+) transporter RhCG. Net NH(4)(+) transport in the secretory direction determined by (14)C-methylammonium (MA) uptake and flux occurred in T84 cells suggesting functional RhG protein activity. The occurrence of NH(4)(+) transport in the secretory direction within a colonic crypt cell model likely serves to minimize net absorption of NH(4)(+) because of surface cell NH(4)(+) absorption. These findings suggest that we rethink the present limited understanding of NH(4)(+) handling by the distal colon as being due solely to passive absorption.
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- 2008
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10. Transplantation of hamster buccal pouch carcinoma to neonatal hamsters.
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Merk LP, Shklar G, and Albright J
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- 9,10-Dimethyl-1,2-benzanthracene, Abdominal Neoplasms pathology, Anaplasia pathology, Animals, Animals, Newborn, Carcinoma, Squamous Cell chemically induced, Carcinoma, Squamous Cell pathology, Cheek, Cricetinae, Mesocricetus, Mouth Neoplasms chemically induced, Mouth Neoplasms pathology, Neoplasm Transplantation, Neoplasms, Experimental chemically induced, Neoplasms, Experimental pathology, Neoplasms, Experimental surgery, Peritoneal Neoplasms pathology, Transplantation, Homologous, Carcinoma, Squamous Cell surgery, Mouth Neoplasms surgery
- Abstract
Epidermoid carcinomas of oral mucosa were induced with DMBA in the buccal pouches of hamsters. The well-differentiated primary tumors were allografted into the peritoneal cavities of neonatal hamsters that had been treated with antilymphocyte serum. Solid tumors grew rapidly in the peritoneum and were harvested 6 to 31 days postimplantation. Gross and histopathologic specimens revealed infiltrative masses of tumor that had become more anaplastic than the original tumor. This in vivo model has considerable potential as a means of studying the immunology of oral cancers during tumor progression.
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- 1979
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11. KLE: a cell line with defective estrogen receptor derived from undifferentiated endometrial cancer.
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Richardson GS, Dickersin GR, Atkins L, MacLaughlin DT, Raam S, Merk LP, and Bradley FM
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- Adenocarcinoma metabolism, Adenocarcinoma ultrastructure, Aged, Aneuploidy, Animals, Cell Line, Female, Humans, Karyotyping, Mice, Mice, Nude, Microscopy, Electron, Neoplasm Transplantation, Phenotype, Transplantation, Heterologous, Uterine Neoplasms metabolism, Uterine Neoplasms ultrastructure, Adenocarcinoma pathology, Receptors, Estrogen analysis, Uterine Neoplasms pathology
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KLE is a cell line derived from a poorly differentiated endometrial carcinoma that is aneuploid with chromosome numbers ranging from 51 to 66 and 6-8 marker chromosomes demonstrated by G banding. Tumors harvested from five of five nude mice bearing an inoculum for more than a month resemble the original specimen, and electron microscopy shows microvilli, many junctional processes, glycogenation, and a prominent nucleolonema. The cell cytosol contains a specific binder for estradiol, but there is no estrogen receptor in the nucleus and in a study reported elsewhere (Raam et al., Breast Cancer Res. Treat. 2, 277 (1982) ) translocation to the nucleus fails to occur. The enzyme phenotype of this cell is human, non-HeLa.
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- 1984
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12. Immunological, biochemical, ultrastructural, and electrophysiological characteristics of a human glioblastoma-derived cell culture line.
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Black PM, Kornblith PL, Davison PF, Liszczak TM, Merk LP, Smith BH, McKeever PE, and Quindlen EA
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- Brain Neoplasms immunology, Brain Neoplasms ultrastructure, Cell Division, Cell Line, Cells, Cultured, Electrophysiology, Glioblastoma immunology, Glioblastoma ultrastructure, Humans, Karyotyping, Male, Microscopy, Electron, Microscopy, Electron, Scanning, Middle Aged, Brain Neoplasms physiopathology, Glioblastoma physiopathology
- Abstract
This report presents the results of a study using multiple techniques of the established human cell line, LM, which has been developed in culture medium from a patient with a right temporoparietal glioblastoma. This cell line has human subtetraploid karyotype and has several features of a transformed line in culture. These include continuous propagation for 10 years, ability to form tumor nodules when transplanted into immunologically suppressed hamsters, and pleomorphic appearance. Ultrastructurally, it is characterized by multiple nuclei, few actin cables, and numerous surface-membrane microvilli, as well as abundant 9- to 10-nm cytoplasmic filaments. By its immunological reactivity, the line can be shown to contain glial fibrillary acidic protein at low levels, consistent with its glial origin and continued nature. Dibutyryl cyclic adenosine monophosphate (db-cAMP) induces formation of long astrocytic-like processes as well. Its membrane electrical characteristics include a low resting membrane potential and short time constant. Used in a microtiter antiglioma antibody cytotoxicity assay, LM yields a positive reaction to antibodies in the sera of 80% of patients with astrocytomas and only 9% of normal blood-bank donors, suggesting that it shares common antigens with other astrocytic tumor lines. The varied characteristics of this glioblastoma-derived line emphasize the "multiforme" nature on the neoplasm and suggest that for characterization of any such line, multiple parameters are necessary to allow comparison with other long-term glioblastoma lines in the literature. The usefulness of the LM line in in vitro cell biological, immunological, chemotherapeutic, and radiobiological studies of gliomas makes such efforts very worthwhile.
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- 1982
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13. Chemotherapy and immunotherapy of three human lymphomas serially transplantable in the neonatal Syrian hamster.
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Adams RA, Flowers A, Sundeen R, and Merk LP
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- Age Factors, Animals, Animals, Newborn, Antilymphocyte Serum, Cricetinae, Cyclophosphamide therapeutic use, Dactinomycin therapeutic use, Female, Immune Sera, Leukemia, Lymphoid blood, Lymphocyte Transfusion, Lymphoma drug therapy, Lymphoma etiology, Maternal-Fetal Exchange, Mercaptopurine therapeutic use, Methotrexate therapeutic use, Neoplasm Transplantation, Neoplasms, Experimental drug therapy, Prednisone therapeutic use, Pregnancy, Spleen immunology, Time Factors, Vincristine therapeutic use, Immunization, Passive, Lymphoma therapy
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- 1972
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14. Effects of infant thymectomy and antilymphocyte serum on xenotransplantation of a human leukemia in the hamster.
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Merk LP and Adams RA
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- Animals, Animals, Newborn, Brain pathology, Cricetinae, Female, Graft Rejection, Humans, Immunosuppression Therapy, Leukocyte Count, Male, Pregnancy, Rabbits immunology, Stimulation, Chemical, Thymus Gland immunology, Transplantation, Heterologous, Antilymphocyte Serum pharmacology, Leukemia, Lymphoid immunology, Neoplasm Transplantation, Thymectomy
- Published
- 1972
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