25 results on '"Mboera, Leonard E.G."'
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2. Rift Valley fever seropositivity in humans and domestic ruminants and associated risk factors in Sengerema, Ilala, and Rufiji districts, Tanzania
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Sindato, Calvin, Karimuribo, Esron D., Vairo, Francesco, Misinzo, Gerald, Rweyemamu, Mark M., Hamid, Muzamil Mahdi Abdel, Haider, Najmul, Tungu, Patrick K., Kock, Richard, Rumisha, Susan F., Mbilu, Togolai, Ntoumi, Francine, Zumla, Alimuddin, and Mboera, Leonard E.G.
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- 2022
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3. Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania
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Mwanyika, Gaspary O., Sindato, Calvin, Rugarabamu, Sima, Rumisha, Susan F., Karimuribo, Esron D., Misinzo, Gerald, Rweyemamu, Mark M., Abdel Hamid, Muzamil M., Haider, Najmul, Vairo, Francesco, Kock, Richard, and Mboera, Leonard E.G.
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- 2021
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4. Seroprevalence and associated risk factors of selected zoonotic viral hemorrhagic fevers in Tanzania
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Rugarabamu, Sima, Mwanyika, Gaspary O., Rumisha, Susan F., Sindato, Calvin, Lim, Hee-Young, Misinzo, Gerald, and Mboera, Leonard E.G.
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- 2021
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5. Policy actors and human and animal health practitioners’ perceptions of antimicrobial use and resistance in Tanzania: A qualitative study
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Frumence, Gasto, Mboera, Leonard E.G., Katale, Bugwesa Z., Sindato, Calvin, Kimera, Sharadhuli, Durrance-Bagale, Anna, Mshana, Stephen E., Clark, Taane G., Rweyemamu, Mark M., Legido-Quigley, Helena, and Matee, Mecky
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- 2021
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6. Emerging epidemics: is the Zanzibar healthcare system ready to detect and respond to mosquito-borne viral diseases?
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Saleh, Fatma, Kitau, Jovin, Konradsen, Flemming, Mboera, Leonard E.G., and Schiøler, Karin L.
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- 2021
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7. Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention
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Nicastri, Emanuele, Kobinger, Gary, Vairo, Francesco, Montaldo, Chiara, Mboera, Leonard E.G., Ansunama, Rashid, Zumla, Alimuddin, and Ippolito, Giuseppe
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- 2019
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8. Molecular epidemiological survey of pathogenic trypanosomes in naturally infected cattle in northern Côte d'ivoire.
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Ekra, Jean-Yves, N'Goran, Edouard K., Mboera, Leonard E.G., Gragnon, Biégo Guillaume, Nadège Assovié, Koco Rita, and Mafie, Eliakunda Michael
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MOLECULAR epidemiology ,CATTLE diseases ,CATTLE breeds ,PATHOGENIC microorganisms - Abstract
Bovine trypanosomiasis is a significant health concern for livestock intensification in Côte d'Ivoire. This study aimed to determine the prevalence and distribution of pathogenic trypanosomes and identify the most infected cattle breed in northern Côte d'Ivoire. We examined 700 cattle and found that polymerase chain reaction (PCR) was more sensitive (12.3%) than microscopic observation (5.6%). Among the trypanosome species detected in naturally infected cattle, Trypanosoma vivax was 7.3%, Trypanosoma simiae tsavo was 6.7%, and Trypanosoma congolense was 0.4%. The overall prevalence of trypanosome infection in all cattle breeds was 12.3%, while the prevalence in individual breeds was 14.8%, 7.3%, 10.6%, and 12.3% for N'Dama, Baoule, Zebu, and Mere breed, respectively. The infected animals had low packed cell volume, influencing the prevalence. Our findings indicate that bovine trypanosomes are prevalent in Côte d'Ivoire, and their prevalence varies by region and breed. These pathogens include T. vivax, T. simiae tsavo, and T. congolense. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Clinical, virologic, and epidemiologic characteristics of dengue outbreak, Dar es Salaam, Tanzania, 2014
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Vairo, Francesco, Mboera, Leonard E.G., De Nardo, Pasquale, Oriyo, Ndekya M., Meschi, Silvia, Rumisha, Susan F., Colavita, Francesca, Mhina, Athanas, Carletti, Fabrizio, Mwakapeje, Elibariki, Capobianchi, Maria Rosaria, Castilletti, Concetta, Di Caro, Antonino, Nicastri, Emanuele, Malecela, Mwelecele N., and Ippolito, Giuseppe
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Biological products industry -- Health aspects ,Dengue -- Health aspects ,Infection -- Health aspects ,Malaria -- Health aspects ,Dengue viruses -- Health aspects ,Health ,World Health Organization - Abstract
Data are scarce on seroprevalence of dengue virus (DENV) in Tanzania. Cross-sectional studies conducted during 2007-2014 indicated that DENV seroprevalence ranged from 50%, depending on geographic area and epidemiologic characteristics [...]
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- 2016
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10. Midterm review of national health plans: an example from the United Republic of Tanzania/Examen a mi-parcours des plans nationaux de sante: l'exemple de la Republique-Unie de Tanzanie/Revision intermedio de los planes de salud nacionales: un ejemplo de la Republica Unidad de Tanzania
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Mboera, Leonard E.G., Ipuge, Yahya, Kumalija, Claud J., Rubona, Josbert, Perera, Sriyant, Masanja, Honorati, and Boerma, Ties
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National health insurance -- Analysis -- Surveys ,Health ,World Health Organization -- Surveys - Abstract
In the health sector, planning and resource allocation at country level are mainly guided by national plans. For each such plan, a midterm review of progress is important for policy-makers since the review can inform the second half of the plan's implementation and provide a situation analysis on which the subsequent plan can be based. The review should include a comprehensive analysis using recent data--from surveys, facility and administrative databases--and global health estimates. Any midterm analysis of progress is best conducted by a team comprising representatives of government agencies, independent national institutions and global health organizations. Here we present an example of such a review, done in 2013 in the United Republic of Tanzania. Compared to similar countries, the results of this midterm review showed good progress in all health indicators except skilled birth attendance. Dans le secteur de la sante, la planification et l'allocation des ressources au niveau national sont principalement guidees par les plans des pays. Pour chacun de ces plans, un examen a mi-parcours des progres realises est important pour les responsables politiques, puisque cet examen peut donner des Informations pour la deuxieme moitie de la mise en oeuvre du plan et fournir une analyse de la situation a partir de laquelle la suite du plan peut se baser. Lfexamen devrait inclure une analyse complete utilisant les donnees recentes (obtenues a partir des bases de donnees des enquetes, des etablissements et de l'administration) et les estimations sanitaires mondiales. Toute analyse a mi-parcours des progres realises doit etre menee de preference par une equipe comprenant des representants des agences gouvernementales, des institutions nationales independantes et des organisations sanitaires mondiales. Nous presentons ici un exemple d'un tel examen, realise en 2012 dans la Republique-Unie de Tanzanie. Par rapport a d'autres pays similaires, les resultats de cet examen a mi-parcours montrent une progression satisfaisante de tous les indicateurs de sante, a l'exception de l'accouchement assiste par un soignant qualifie. En el sector de la salud, la planificacion y la asignacion de recursos a nivel nacional se guian principalmente por planes nacionales. Para los planificadores de politicas es importante contar una revision intermedia de los progresos de cada plan, ya que puede proporcionar informacion sobre la segunda mitad de la implementadon del plan y un analisis de la situacion en la que basar planes posteriores. La revision debe incluir u n analisis exhaustivo con datos recientes--a partir de encuestas y bases de datos administrativas y de los centros--y estimaciones mundiales de salud. La mejor manera de realizar cualquier analisis intermedio de los progresos es a traves de un equipo integrado por representantes de organismos gubernamentales, instituciones nacionales independientes y organizaciones mundiales de salud. Aqui presentamos un ejemplo de ese tipo de revisiones, realizada en 2012 en Tanzania. En comparacion con paises similares, los resultados de este examen intermedio mostraron un progreso correcto en todos los indicadores de salud, excepto en la prestacion de atencion especializada en el parto., Introduction In the health sector, regular reviews of progress and performance are critical for good planning and resource allocation. Most countries have a national strategic plan for the health sector [...]
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- 2015
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11. Comparative assessment of the human and animal health surveillance systems in Tanzania: Opportunities for an integrated one health surveillance platform.
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Mremi, Irene R., Rumisha, Susan F., Sindato, Calvin, Kimera, Sharadhuli I., and Mboera, Leonard E.G.
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PUBLIC health surveillance ,RESEARCH funding - Abstract
Globally, there have been calls for an integrated zoonotic disease surveillance system. This study aimed to assess human and animal health surveillance systems to identify opportunities for One Health surveillance platform in Tanzania. A desk review of policies, acts and strategies addressing disease surveillance that support inter-sectoral collaboration was conducted. A semi-structured questionnaire was administered to key informants from the two sectors. Databases with potential relevance for surveillance were assessed. One Health-focused policies, acts, strategic plans and guidelines emphasising inter-sectoral collaboration strengthening were in place. Stable systems for collecting surveillance data with trained staff to implement surveillance activities at all levels in both sectors were available. While the human surveillance system was a mix of paper-based and web-based, the animal health system was mainly paper-based. The laboratory information system existed in both sectors, though not integrated with the epidemiological surveillance systems. Both the animal and human surveillance systems had low sensitivity to alert outbreaks. The findings indicate that individual, organisational, and infrastructure opportunities that support the integration of surveillance systems from multiple sectors exist. Challenges related to data sharing and quality need to be addressed for the effective implementation of the platform. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Improving disease surveillance data analysis, interpretation, and use at the district level in Tanzania.
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Mremi, Irene R., Sindato, Calvin, Kishamawe, Coleman, Rumisha, Susan F., Kimera, Sharadhuli I., and Mboera, Leonard E.G.
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PREVENTION of epidemics ,PUBLIC health surveillance ,EVALUATION of human services programs ,RESEARCH methodology ,ATTITUDES of medical personnel ,MOTIVATION (Psychology) ,INTERVIEWING ,DATABASE management ,HUMAN services programs ,PRE-tests & post-tests ,QUALITY assurance ,RESEARCH funding ,DESCRIPTIVE statistics ,PROFESSIONAL competence ,ACCESS to information ,DATA analysis ,PHYSICIAN practice patterns ,HEMORRHAGIC fever ,STANDARDS - Abstract
An effective disease surveillance system is critical for early detection and response to disease epidemics. This study aimed to assess the capacity to manage and utilize disease surveillance data and implement an intervention to improve data analysis and use at the district level in Tanzania. Mapping, in-depth interview and desk review were employed for data collection in Ilala and Kinondoni districts in Tanzania. Interviews were conducted with members of the council health management teams (CHMT) to assess attitudes, motivation and practices related to surveillance data analysis and use. Based on identified gaps, an intervention package was developed on basic data analysis, interpretation and use. The effectiveness of the intervention package was assessed using pre-and post-intervention tests. Individual interviews involved 21 CHMT members (females = 10; males = 11) with an overall median age of 44.5 years (IQR = 37, 53). Over half of the participants regarded their data analytical capacities and skills as excellent. Analytical capacity was higher in Kinondoni (61%) than Ilala (52%). Agreement on the availability of the opportunities to enhance capacity and skills was reported by 68% and 91% of the participants from Ilala and Kinondoni, respectively. Reported challenges in disease surveillance included data incompleteness and difficulties in storage and accessibility. Training related to enhancement of data management was reported to be infrequently done. In terms of data interpretation and use, despite reporting of incidence of viral haemorrhagic fevers for five years, no actions were taken to either investigate or mitigate, indicating poor use of surveillance data in monitoring disease occurrence. The overall percentage increase on surveillance knowledge between pre-and post-training was 37.6% for Ilala and 20.4% for Kinondoni indicating a positive impact on of the training. Most of CHMT members had limited skills and practices on data analysis, interpretation and use. The training in data analysis and interpretation significantly improved skills of the participants. [ABSTRACT FROM AUTHOR]
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- 2022
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13. Supply chain management of laboratory supportive services and its potential implications on the quality of HIV diagnostic services in Tanzania
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Kagaruki, Gibson B., Kamugisha, Mathias L., Kilale, Andrew M., Kamugisha, Erasmus, Rutta, Acleus S.M, Baraka, Vito, Mandara, Celine I., Magesa, Stephen M., Materu, Godlisten, Kahwa, Amos M., Madebe, Rashid, Massaga, Julius J., Lemnge, Martha M., Mboera, Leonard E.G., Ishengoma, Deus I., and Global Fund for AIDS, Tuberculosis and Malaria (Grant Number 2013/20).
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laboratory services, supply chain, diagnosis, HIV/AIDS, Tanzania - Abstract
Background: Reliable supply of laboratory supportive services contributes significantly to the quality of HIV diagnostic services. This study assessed the status of supply chain management of laboratory supportive services and its potential implications on the quality of HIV diagnostic services in selected districts of Tanzania.Methods: The study was conducted in 39 health facilities (HFs) from eight districts in four regions of Tanzania, namely Iringa, Mtwara, Tabora and Tanga. Facilities with care and treatment centres for HIV/AIDS patients were purposively selected for the study. The study utilized a quantitative method of data collection. A questionnaire was administered to heads of laboratories to obtain information on laboratory supply chain management.Results: A total of 39 health facilities (HF) were included in the study. This included 23 public and 16 private facilities. In 82% of the HFs, ordering of supplies was performed by the laboratory departments. The information commonly used to forecast requirements of the laboratories included the number of tests done (74.4%; n=29), current stock levels (69.2%; n=27), average monthly consumption (64.1%, n=25) and minimum and maximum stock levels (10.2%, n=4). Emergency orders were significantly common in public than private facilities (73.9% vs. 56.3%, p=0.004). Delivery of ordered supplies took 1 to 180 days with a significantly longer period for public than private facilities (32.5 vs. 13.1 days, p=0.044). Most of the public HFs ordered supplies from diverse sources compared to private facilities (68.2% vs. 31.8%).Conclusion: There was a weak inventory management system and delays in delivery of supplies in the majority of HFs, which are likely to impede quality of HIV care and treatment. Strengthening capacity for data management and ensure constant supply will potentially improve the quality of HIV diagnostic services.
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- 2018
14. Exploiting the chemical ecology of mosquito oviposition behavior in mosquito surveillance and control: a review.
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Mwingira, Victor, Mboera, Leonard E.G., Dicke, Marcel, and Takken, Willem
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Vector control is an important component of the interventions aimed at mosquito‐borne disease control. Current and future mosquito control strategies are likely to rely largely on the understanding of the behavior of the vector, by exploiting mosquito biology and behavior, while using cost‐effective, carefully timed larvicidal and high‐impact, low‐volume adulticidal applications. Here we review the knowledge on the ecology of mosquito oviposition behavior with emphasis on the potential role of infochemicals in surveillance and control of mosquito‐borne diseases. A search of PubMed, Embase, Web of Science, Global Health Archive, and Google Scholar databases was conducted using the keywords mosquito, infochemical, pheromone, kairomone, allomone, synomone, apneumone, attractant, host‐seeking, and oviposition. Articles in English from 1974 to 2019 were reviewed to gain comprehensive understanding of current knowledge on infochemicals in mosquito resource‐searching behavior. Oviposition of many mosquito species is mediated by infochemicals that comprise pheromones, kairomones, synomones, allomones, and apneumones. The novel putative infochemicals that mediate oviposition in the mosquito subfamilies Anophelinae and Culicinae were identified. The role of infochemicals in surveillance and control of these and other mosquito tribes is discussed with respect to origin of the chemical cues and how these affect gravid mosquitoes. Oviposition attractants and deterrents can potentially be used for manipulation of mosquito behavior by making protected resources unsuitable for mosquitoes (push) while luring them towards attractive sources (pull). In this review, strategies of targeting breeding sites with environmentally friendly larvicides with the aim to develop appropriate trap‐and‐kill techniques are discussed. [ABSTRACT FROM AUTHOR]
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- 2020
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15. Mitigating lockdown challenges in response to COVID-19 in Sub-Saharan Africa
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Mboera, Leonard E.G., Akipede, George O., Banerjee, Amitava, Cuevas, Luis E., Czypionka, Thomas, Khan, Mishal, Kock, Richard, McCoy, David, Mmbaga, Blandina T., Misinzo, Gerald, Shayo, Elizabeth H., Sheel, Meru, Sindato, Calvin, and Urassa, Mark
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- 2020
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16. Policy and decision makers’ perspectives on intersectoral approach in malaria control in Tanzania
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Mlozi, Malongo R.S., Rumisha, Susan F., Mlacha, Tabitha, Bwana, Veneranda M., Shayo, Elizabeth H., Mayala, Benjamin K., Malima, Robert C., Mashoto, Kijakazi O., Mboera, Leonard E.G., and International Development Research Centre, Canada
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malaria, control, intersectoral, collaboration, Tanzania - Abstract
Malaria is a complex health problem that cuts across a number of sectors. Establishing intersectoral linkages is important to facilitate joint efforts to address the problem at the national, district and community levels. The objectives of this study were to explore key stakeholder engagement in malaria control policy formulation and implementation; and to determine decision and policy makers’ opinions as regards to different sectoral activities that contribute to malaria transmission and control and the likelihood that an intersectoral approach in malaria control will be adopted in Tanzania. This study included document analysis, self-administered interviews and group discussions. Interviews and group discussions involved key stakeholders at district and national levels. The sectors involved were health, agriculture, environment, livestock, fisheries, education, works, irrigation, water resources, land development, forestry, and community development. The Ministry of Health and Social Welfare (MoHSW) and the Prime Minister’s Office for Regional Administration and Local Government (PMORALG) were the two key ministries involved in malaria control in both policy formulations and guidelines. Sectoral activities that contribute to malaria transmission to include farming systems, deforestation, fishing, nomadic pastoralism, household water storage, water resource development projects, road/ house construction, brick making, mining, and water drainage systems. The lack of intersectoral approaches in malaria control programme included the fact that the MoHSW does not involve other sectors during planning and development of policy guidelines; different sectoral mandates; differences in disciplines and management culture; lack of a national coordinating body; lack of budget for intersectoral activities, and selfishness among sectors to share resources. In conclusion, the current strategies for malaria control in Tanzania must address issues of livelihoods and human development activities and emphasise the need for intersectoral collaboration. It is recommended that all development projects take into account the potential for an adverse impact on malaria and other health problems. The future of malaria control strategy should therefore, be broad based, and intersectoral in planning and operation.
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- 2014
17. Editorial: Fifty years of health services in Tanzania: What next?
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Mboera, Leonard E.G.
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Before independence in 1961, Tanzania was a Germany colony (1889-1916) and later British Protectorate (1916-1961). During the 72 year period, the western medical services targeted foreigners working for the colonial governments. After independence, the government has expanded the health services with a vision to improve the health and well being of all Tanzanians with a focus on those most at risk, and to encourage the health system to be more responsive to the needs of the people. The policy mission is to facilitate the provision of equitable, quality and affordable basic health services, which are gender sensitive and sustainable, delivered for the achievement of improved health status.This issue of the Tanzania Journal of Health Research is dedicated for the 50th Anniversary of the Tanzania independence. It includes a number of reviews focussed on different aspects of health, both communicable and non-communicable diseases. The reviews focus on a number of health problems that faced Tanzania during the past fifty years. Challenges to meet the national and global development goals are discussed in line with the changing epidemiological patterns for both communicable and non-communicable diseases.
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- 2012
18. Access and utilisation of healthcare services in rural Tanzania: A comparison of public and non-public facilities using quality, equity, and trust dimensions.
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Shayo, Elizabeth H., Senkoro, Kesheni P., Momburi, Romanus, Olsen, Øystein E., Byskov, Jens, Makundi, Emmanuel A., Kamuzora, Peter, and Mboera, Leonard E.G.
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MEDICAL care ,CONFIDENCE intervals ,HEALTH facilities ,HEALTH services accessibility ,MEDICAL quality control ,MEDICAL care costs ,PATIENT-professional relations ,PATIENT satisfaction ,PROBABILITY theory ,QUESTIONNAIRES ,RESEARCH funding ,TRUST ,LOGISTIC regression analysis ,PRIVATE sector ,PUBLIC sector ,DATA analysis software ,DESCRIPTIVE statistics ,ODDS ratio - Abstract
This study compared the access and utilisation of health services in public and non-public health facilities in terms of quality, equity and trust in the Mbarali district, Tanzania. Interviews, focus group discussions, and informal discussions were used to generate data. Of the 1836 respondents, 1157 and 679 respondents sought healthcare services on their last visit at public or non-public health facilities, respectively. While 45.5% rated the quality of services to be good in both types of facilities, reported medicine shortages were more pronounced among those who visited public rather than non-public health facilities (OR = 1.7, 95% CI 1.4, 2.1). Respondents who visited public facilities were 4.9 times less likely than those who visited non-public facilities to emphasise the influence of cost in accessing and utilising health care (OR = 4.9, CI 3.9–6.1). A significant difference was also found in the provider–client relationship satisfaction level between non-public (89.1%) and public facilities (74.7%) (OR = 2.8, CI: 1.5–5.0), indicating a level of lower trust in the later. Revised strategies are needed to ensure availability of medicines in public facilities, which are used by the majority of the population, while strengthening private–public partnerships to harmonise healthcare costs. [ABSTRACT FROM PUBLISHER]
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- 2016
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19. Challenges and opportunities for implementing an intersectoral approach in malaria control in Tanzania.
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MLOZI, MALONGO R.S., RUMISHA, SUSAN F., MLACHA, TABITHA, BWANA, VENERANDA M., SHAYO, ELIZABETH H., MAYALA, BENJAMIN K., MALIMA, ROBERT C., MASHOTO, KIJAKAZI O., and MBOERA, LEONARD E.G.
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Background: Malaria is a complex health problem related to socio-economic and environmental factors that cut across a number of sectors. Establishing intersectoral linkages is important to facilitate joint efforts to address the problem at all levels. The objectives of this study were to explore key sectoral engagements in malaria control policy formulation and implementation, and to determine decision and policy makers' opinions about different sectoral activities that contribute to malaria transmission and control in Tanzania. Methods: This study included documentary review, self-administered interviews and group discussion. Interviews and group discussions involved key informants at district and national levels. The sectors involved were health, agriculture, environment, livestock, fisheries, education, works, irrigation, water resources, land development, forestry, and community development. Results: Institutions and organizations that were involved in the development of the previous and current National Malaria Strategic Plan (2007-2013 and 2013-2020) were the Ministries of Health and Social Welfare, Prime Minister's Office of Regional Administration and Local Government, Public universities and non-governmental organizations. All the individuals involved in the development of the plans were either medical or health professionals. According to key informants, sectoral activities identified to contribute to malaria transmission included farming systems, deforestation, fishing, nomadic pastoralism, household water storage, water resource development projects, road and house construction and mining. The lack of intersectoral approaches in malaria control programme included the facts that the Health Sector does not involve other sectors during planning and development of policy guidelines, differences in sectoral mandates and management culture, lack of a national coordinating framework and lack of budget for intersectoral activities. Conclusion: The current strategies for malaria control in Tanzania need to address socio-economic and development activities across sectors and emphasise the need for intersectoral collaboration. It is recommended that the future of malaria control strategies should, therefore, be broad based and intersectoral in planning and implementation. [ABSTRACT FROM AUTHOR]
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- 2015
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20. Regional Initiatives in Support of Surveillance in East Africa: The East Africa Integrated Disease Surveillance Network (EAIDSNet) Experience.
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Ope, Maurice, Sonoiya, Stanley, Kariuki, James, Mboera, Leonard E.G, Gandham, Ramana N.V, Schneidman, Miriam, and Kimura, Mwihaki
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MALARIA ,PANDEMICS - Abstract
The East African Integrated Disease Surveillance Network (EAIDSNet) was formed in response to a growing frequency of cross-border malaria outbreaks in the 1990s and a growing recognition that fragmented disease interventions, coupled with weak laboratory capacity, were making it difficult to respond in a timely manner to the outbreaks of malaria and other infectious diseases. The East Africa Community (EAC) partner states, with financial support from the Rockefeller Foundation, established EAIDSNet in 2000 to develop and strengthen the communication channels necessary for integrated cross-border disease surveillance and control efforts. The objective of this paper is to review the regional EAIDSNet initiative and highlight achievements and challenges in its implementation. Major accomplishments of EAIDSNet include influencing the establishment of a Department of Health within the EAC Secretariat to support a regional health agenda; successfully completing a regional field simulation exercise in pandemic influenza preparedness; and piloting a web-based portal for linking animal and human health disease surveillance. The strategic direction of EAIDSNet was shaped, in part, by lessons learned following a visit to the more established Mekong Basin Disease Surveillance (MBDS) regional network. Looking to the future, EAIDSNet is collaborating with the East, Central and Southern Africa Health Community (ECSA-HC), EAC partner states, and the World Health Organization to implement the World Bank-funded East Africa Public Health Laboratory Networking Project (EAPHLNP). The network has also begun lobbying East African countries for funding to support EAIDSNet activities. [ABSTRACT FROM AUTHOR]
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- 2013
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21. Plasmodium falciparum and helminth coinfections among schoolchildren in relation to agro-ecosystems in Mvomero District, Tanzania
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Mboera, Leonard E.G., Senkoro, Kesheni P., Rumisha, Susan F., Mayala, Benjamin K., Shayo, Elizabeth H., and Mlozi, Malongo R.S.
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PLASMODIUM falciparum , *SCHOOL children , *HELMINTHS , *MALARIA , *AGRICULTURAL ecology , *SCHISTOSOMA haematobium , *HOOKWORMS , *JUVENILE diseases - Abstract
Abstract: Background: In Sub-Saharan Africa, some individuals infected with malaria are also infected with helminths. However, the magnitude and distribution of such coinfections in relation to eco-systems remains poorly defined. This study was undertaken to determine the prevalence of Plasmodium falciparum and helminth coinfections among schoolchildren in relation to agro-ecosystems in Mvomero District, Tanzania. Methods: The agro-ecosystems were categorised as sugarcane, traditional flooding rice irrigation, improved non-flooding rice irrigation and savannah. Schoolchildren had their blood examined for P. falciparum and Wuchereria bancrofti; urine for Schistosoma haematobium and stool for intestinal helminths. Blood samples were also examined for haemoglobin concentration. Results: A total of 578 schoolchildren (mean age=7.96 years) were involved in the study. Overall, 60% of all schoolchildren had at least an infection of either P. falciparum, W. bancrofti, S. haematobium or hookworm. The highest prevalence of P. falciparum (75.3%), W. bancrofti (62.9%) and hookworm (24.7%) infections was observed among children in flooding rice irrigation ecosystem. P. falciparum + S. haematobium (10.9%) and P. falciparum + W. bancrofti (11.1%) were the most prevalent types of coinfection in the area. The highest prevalence of double parasitic infections was observed among children in the flooding rice irrigation ecosystems. The risk for acquiring coinfections of P. falciparum + W. bancrofti was significantly higher among children in the flooding rice irrigation ecosystem. Forty-five (7.8%) children were coinfected with three types of parasitic infections. The risk of acquiring triple infection among children from flooding rice irrigation was higher for P. falciparum + S. haematobium + W. bancrofti (p <0.001). Seven schoolchildren (1.2%) were found infected with four parasites and all were from the flooding rice irrigation ecosystem. Significantly high P. falciparum geometric parasite density was observed among children coinfected with either hookworms or W. bancrofti (p <0.001). On average, 17.8% (103/578) of the children had enlarged spleens. Over 3- and 4-folds increase in the risk of having an enlarged spleen were observed among children coinfected with P. falciparum + S. haematobium and P. falciparum + W. bancrofti, respectively. The overall prevalence of anaemia (<11.5g/dl) was 61.9% (358/578). Conclusion: Malaria–helminth coinfections are prevalent among schoolchildren in rural Tanzania and the pattern varies between agro-ecosystems. Results of this study suggest that integrated control of malaria and helminthes should be designed based on the local agro-ecosystems. [Copyright &y& Elsevier]
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- 2011
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22. Knowledge, perceptions and practices of farming communities on linkages between malaria and agriculture in Mvomero District, Tanzania
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Mboera, Leonard E.G., Shayo, Elizabeth H., Senkoro, Kesheni P., Rumisha, Susan F., Mlozi, Malongo R.S., and Mayala, Benjamin K.
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PUBLIC health , *MEDICAL education , *INSECTICIDES , *MOSQUITO nets , *CROP science , *AGRICULTURE ,MALARIA transmission - Abstract
Abstract: This study was carried out to determine knowledge, perceptions and practices of farming communities on linkages between agriculture and malaria in Mvomero District in Tanzania. A total of 661 adult males and females were interviewed using a structured questionnaire. Most respondents (85.6%) were engaged in crop production. Significantly, a larger proportion (55.2%) of the respondents had primary school education (P <0.001). Majority (88.2%) respondents described malaria as the most important public health problem. However, only 48.2% of the respondents had high knowledge of malaria. The level of knowledge on malaria was associated with level of education of the respondent. Those who had attended at least primary school education were more knowledgeable that those without formal education. A significantly larger proportion (67%) of the respondents experienced most malaria episodes during the rainy season (P <0.001). Respondents with low knowledge on malaria experienced 2.3 times more malaria cases in their households than those with higher knowledge. Respondents with low knowledge preferred to seek care from health facilities (OR: 7.28) than those with high knowledge (OR: 0.15). Rice farming was significantly associated with malaria transmission compared to either maize or sugarcane farming (P <0.001). Cattle, sheep and goats were the domestic animals most frequently incriminated to create aquatic habitats for mosquito breeding. Householders with formal education (OR: 4.6, CI: 1.33–15.89, P-value=0.016) and higher knowledge (OR: 1.7, CI: 1.15–2.55, P-value=0.008) reported to incur large losses when having a malaria case than those without education/low knowledge. Majority (60.2%) of the respondent owned at least an insecticide treated mosquito net (ITN). Respondents with higher knowledge of malaria were likely to own at least an ITN than those with low knowledge (P <0.001). In conclusion, the knowledge on malaria and its linkage with agriculture among farming communities in Mvomero District is low. Malaria is a complex health problem and its control approach needs understanding of the environmental factors associated with agricultural practices. It therefore is important that education and communication messages on malaria targeting farming communities take into consideration local agricultural practices. [Copyright &y& Elsevier]
- Published
- 2010
- Full Text
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23. Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics.
- Author
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Gahamanyi, Noel, Song, Dae-Geun, Cha, Kwang Hyun, Yoon, Kye-Yoon, Mboera, Leonard E.G., Matee, Mecky I., Mutangana, Dieudonné, Amachawadi, Raghavendra G., Komba, Erick V.G., and Pan, Cheol-Ho
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NATURAL products ,CAMPYLOBACTER ,ANTIBIOTICS ,DRUG resistance in bacteria ,PLANT extracts - Abstract
Campylobacter species have developed resistance to existing antibiotics. The development of alternative therapies is, therefore, a necessity. This study evaluates the susceptibility of Campylobacter strains to selected natural products (NPs) and frontline antibiotics. Two C. jejuni strains (ATCC
® 33560TM and MT947450) and two C. coli strains (ATCC® 33559TM and MT947451) were used. The antimicrobial potential of the NPs, including plant extracts, essential oils, and pure phytochemicals, was evaluated by broth microdilution. The growth was measured by spectrophotometry and iodonitrotetrazolium chloride. Antibiotic resistance genes (tet(O) and gyrA) were characterized at the molecular level. The minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) ranged from 25 to 1600 µg/mL. Cinnamon oil, (E)-Cinnamaldehyde, clove oil, eugenol, and baicalein had the lowest MIC and MBC values (25–100 µg/mL). MT947450 and MT947451 were sensitive to erythromycin and gentamicin but resistant to quinolones and tetracycline. Mutations in gyrA and tet(O) genes from resistant strains were confirmed by sequencing. The findings show that NPs are effective against drug-sensitive and drug-resistant Campylobacter strains. The resistance to antibiotics was confirmed at phenotypic and genotypic levels. This merits further studies to decipher the action mechanisms and synergistic activities of NPs. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
24. Process Evaluation of a Community-Based Microbial Larviciding Intervention for Malaria Control in Rural Tanzania.
- Author
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Berlin Rubin, Nina, Mboera, Leonard E.G., Lesser, Adriane, Miranda, Marie Lynn, and Kramer, Randall
- Published
- 2020
- Full Text
- View/download PDF
25. Social determinants of malaria and health care seeking patterns among rice farming and pastoral communities in Kilosa District in central Tanzania.
- Author
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Shayo, Elizabeth H., Rumisha, Susan F., Mlozi, Malongo R.S., Bwana, Veneranda M., Mayala, Benjamin K., Malima, Robert C., Mlacha, Tabitha, and Mboera, Leonard E.G.
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RICE farming , *HEALTH behavior , *RICE planting rites , *MEDICAL care , *COMMUNITY coordination ,AGRICULTURAL associations - Abstract
This study was carried out to understand the role social determinants and health seeking behavior among rice farming and pastoral communities in Kilosa District in central Tanzania. The study involved four villages; two with rice farming communities while the other two with pastoral communities. In each village, heads of households or their spouses were interviewed to seek information on livelihoods activities, knowledge and practices on malaria and its preventions. A total of 471 individuals (males = 38.9%; females = 61.1%) were interviewed. Only 23.5% of the respondents had adequate knowledge on malaria. Fifty-six percent of the respondents could not associate any livelihood activity with malaria transmission. Majority (79%) of the respondents believed that most of fevers were due to malaria; this was higher among the pastoral (81.7%) than rice farming communities (76.1%) ( p = 0.038). Cases of fever were significantly higher in households with non-educated (31.2%) than educated respondents (21.5%). Women experienced significantly more episodes of fever than men ( p < 0.001). Of the total of 2606 individuals living in the households, 26.9% were reported to have had fever in the previous three months. Fever was reported more frequently among pastoral than rice farming communities ( p < 0.01). Of those who had fever, 36.6% were clinically diagnosed with malaria and 22.9% were confirmed to be infected with malaria. A combination of fever + convulsions or joint pains + headache was most frequently perceived to be malaria. Treatment seeking frequency differed by the size of the household and between rice farming and pastoral communities ( p = 0.05). In conclusion, education, sex, availability of health care facility and livelihood practices were the major social determinants that influence malaria acquisition and care seeking pattern in central Tanzania. Appropriate public health promotion should be designed to address the links of livelihoods and malaria transmission among rural farming communities in an ecohealth approach. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
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