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168 results on '"Maza, Maria"'

1. Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

Author

Guo, Christina, Sharp, Adam, Gurel, Bora, Crespo, Mateus, Figueiredo, Ines, Jain, Suneil, Vogl, Ursula, Rekowski, Jan, Rouhifard, Mahtab, Gallagher, Lewis, Yuan, Wei, Carreira, Suzanne, Chandran, Khobe, Paschalis, Alec, Colombo, Ilaria, Stathis, Anastasios, Bertan, Claudia, Seed, George, Goodall, Jane, Raynaud, Florence, Ruddle, Ruth, Swales, Karen E., Malia, Jason, Bogdan, Denisa, Tiu, Crescens, Caldwell, Reece, Aversa, Caterina, Ferreira, Ana, Neeb, Antje, Tunariu, Nina, Westaby, Daniel, Carmichael, Juliet, Fenor de la Maza, Maria Dolores, Yap, Christina, Matthews, Ruth, Badham, Hannah, Prout, Toby, Turner, Alison, Parmar, Mona, Tovey, Holly, Riisnaes, Ruth, Flohr, Penny, Gil, Jesus, Waugh, David, Decordova, Shaun, Schlag, Anna, Calì, Bianca, Alimonti, Andrea, and de Bono, Johann S.

Published
2023
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3. Development and Validation of a New BAG-1L–Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer

Author

Neeb, Antje, Figueiredo, Ines, Gurel, Bora, Nava Rodrigues, Daniel, Rekowski, Jan, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Crespo, Mateus, Westaby, Daniel, de Los Dolores Fenor de La Maza, Maria, Guo, Christina, Carmichael, Juliet, Grochot, Rafael, Tunariu, Nina, Cato, Andrew C.B., Plymate, Stephen R., de Bono, Johann S., and Sharp, Adam

Published
2023
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9. B7-H3 as a Therapeutic Target in Advanced Prostate Cancer

Author

Guo, Christina, Figueiredo, Ines, Gurel, Bora, Neeb, Antje, Seed, George, Crespo, Mateus, Carreira, Suzanne, Rekowski, Jan, Buroni, Lorenzo, Welti, Jon, Bogdan, Denisa, Gallagher, Lewis, Sharp, Adam, Fenor de la Maza, Maria D., Rescigno, Pasquale, Westaby, Daniel, Chandran, Khobe, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Calì, Bianca, Alimonti, Andrea, Bressan, Silvia, Nguyen, Alana H.T., Shen, Michael M., Hawley, Jessica E., Obradovic, Aleksandar, Drake, Charles G., Bertan, Claudia, Baker, Chloe, Tunariu, Nina, Yuan, Wei, and de Bono, Johann S.

Published
2023
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11. Immune Biomarkers in Metastatic Castration-resistant Prostate Cancer

Author

Fenor de la Maza, María Dolores, Chandran, Khobe, Rekowski, Jan, Shui, Irene M., Gurel, Bora, Cross, Emily, Carreira, Suzanne, Yuan, Wei, Westaby, Daniel, Miranda, Susana, Ferreira, Ana, Seed, George, Crespo, Mateus, Figueiredo, Ines, Bertan, Claudia, Gil, Veronica, Riisnaes, Ruth, Sharp, Adam, Rodrigues, Daniel Nava, Rescigno, Pasquale, Tunariu, Nina, Liu, Xiao Qiao, Cristescu, Razvan, Schloss, Charles, Yap, Christina, and de Bono, Johann S.

Published
2022
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17. Integrated drag coefficient formula for estimating the wave attenuation capacity of Rhizophora sp. mangrove forests.

Author

Lopez-Arias, Fernando, Maza, Maria, Calleja, Felipe, Govaere, Georges, and Lara, Javier L.

Subjects
MANGROVE forests, MANGROVE plants, DRAG coefficient, RHIZOPHORA, GEOMETRIC distribution, WAVE energy
Abstract

Recently, bulk drag coefficient (~CD) formulations used to quantify wave energy dissipation by Rhizophora mangroves were developed from laboratory data; however, these formulations have not yet been validated with field data. Additionally, due to the complex geometry of mangrove trees within forests and spatial variability, common criteria for determining the adequate geometric characteristics of mangrove forests are lacking and are required to obtain accurate definitions for ~CD. This paper addresses these knowledge gaps by proposing a newly integrated ~CD formulation based on the comprehensive characterization of a Rhizophora mangle forest combined with wave measurements in field, and by using numerical modeling for the calibration process. The field campaign consisted of 23 continuous days of recorded wave data and spatial distribution observations of the geometric characteristics of the mangrove forest. The variation in frontal area per unit height per square meter (Ahm) along the mangrove forest was reported for three zones with different densities identified along the study transect, with decreasing root density from the vegetation edge to the forest interior. On average, the incident wave height decreased by 34% at 63 m in mangrove forests, and the wave attenuation ratios (r) varied between 0.001 and 0.01 m-1. To estimate the ~CD values associated with these wave height attenuation ratios, the Simulating Waves Nearshore (SWAN) numerical model was used to calibrate the model results with the field observations. The variation in the tree frontal area along the mangrove forest and the wave conditions at the site are considered during the calibration process. To further characterize ~CD for this type of mangrove species, the ~CD values acquired from the calibration together with the values reported in the literature from laboratory experiments are presented as a function of the Keulegan-Carpenter number (KC). Root diameter is defined as the characteristic length according to the inherent geometric characteristics of a Rhizophora sp. forest. The new formulation allows us to predictably estimate ~CD values that can be used as inputs in drag force-based models to estimate the attenuation of wave energy produced by Rhizophora sp. forests. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Phase II trial of pembrolizumab for patients suffering from metastatic castration resistant prostate cancer (mCRPC) with DNA repair defects, high tumour mutation burden, and/or high CD3 counts (PERSEUS1).

Author

Rescigno, Pasquale, Fenor de la Maza, Maria Dolores, Burnett, Stephanie M., Villacampa, Guillermo, Stiles, Morgaine, Cafferty, Fay Helen, Beije, Nick, Carreira, Suzanne, Figueiredo, Ines, Flohr, Penelope, Gurel, Bora, Bertan, Claudia, Westaby, Daniel, Chandran, Khobe, Crespo, Mateus, Perna, Carla, Tunariu, Nina, Sharp, Adam, Yap, Christina, and De Bono, Johann S.

Published
2024
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31. Erratum to 'B7-H3 as a Therapeutic Target in Advanced Prostate Cancer' [Eur Urol 2023;83(3):224–38]

Author

Guo, Christina, Figueiredo, Ines, Gurel, Bora, Neeb, Antje, Seed, George, Crespo, Mateus, Carreira, Suzanne, Rekowski, Jan, Buroni, Lorenzo, Welti, Jon, Bogdan, Denisa, Gallagher, Lewis, Sharp, Adam, Fenor de la Maza, Maria D., Rescigno, Pasquale, Westaby, Daniel, Chandran, Khobe, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, and Alimonti, Andrea

Abstract

European Urology, 83 (6), ISSN:0302-2838

Published
2023
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32. Dietary Advanced Glycation End Products and Their Role in Health and Disease

Author

Uribarri, Jaime, del Castillo, María Dolores, de la Maza, María Pía, Filip, Rosana, Gugliucci, Alejandro, Luevano-Contreras, Claudia, Macías-Cervantes, Maciste H, Markowicz Bastos, Deborah H, Medrano, Alejandra, Menini, Teresita, Portero-Otin, Manuel, Rojas, Armando, Sampaio, Geni Rodrigues, Wrobel, Kazimierz, Wrobel, Katarzyna, and Garay-Sevilla, Ma Eugenia

Published
2015
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35. Identifying knowledge gaps hampering application of intertidal habitats in coastal protection: Opportunities & steps to take

Author

Bouma, Tjeerd J., van Belzen, Jim, Balke, Thorsten, Zhu, Zhenchang, Airoldi, Laura, Blight, Andrew J., Davies, Andrew J., Galvan, Cristina, Hawkins, Steve J., Hoggart, Simon P.G., Lara, Javier L., Losada, Inigo J., Maza, Maria, Ondiviela, Barbara, Skov, Martin W., Strain, Elisabeth M., Thompson, Richard C., Yang, Shilun, Zanuttigh, Barbara, Zhang, Liquan, and Herman, Peter M.J.

Published
2014
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41. Domestic clustered networks and internationalization of agrifood SMEs.

Author

Serrano, Raul, Dejo‐Oricain, Natalia, Ferrer, Juan, Pinilla, Vicente, Abella‐Garcés, Silvia, and Maza, Maria Teresa

Subjects
GLOBALIZATION, SPANISH wines, BUSINESS networks, SMALL business, WINE industry
Abstract

This paper examines how participating in domestic clustered networks in the agri‐food industry affects the export status and export intensity of small and medium‐sized enterprises (SMEs). The Uppsala internationalization process model has been revisited in light of the knowledge that these networks can contribute to promoting the presence of SMEs abroad. The study uses a sample of companies in the Spanish wine industry and characterizes 76 domestic clustered business networks (Protected Designations of Origin). The value and originality of the paper reside in its contribution in terms of measuring the degree of internationalization of domestic clustered networks to which SMEs belong. It also assesses the effect of these networks on the internationalization process of the agri‐food industry, considering that domestic clustered networks with a strong international commitment generate greater internationalization opportunities. [EconLit Citations: F14, M21, Q13, Q17]. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Systemic Regulatory T Cells and IL-6 as Prognostic Factors for Anatomical Improvement of Uveitic Macular Edema

Author

Matas, Jessica, Llorenç, Victor, Fonollosa, Alex, Diaz Valle, David, Esquinas, Cristina, de la Maza, Maria Teresa Sainz, Figueras-Roca, Marc, Artaraz, Joseba, Berasategui, Barbara, Mesquida, Marina, Adan Civera, Alfredo, Molins, Blanca, and Universitat Autònoma de Barcelona

Subjects
0301 basic medicine, Male, Time Factors, Gastroenterology, T-Lymphocytes, Regulatory, regulatory T cells, 0302 clinical medicine, Edema, Immunology and Allergy, Medicine, Flow cytometry, Prospective Studies, Original Research, Aged, 80 and over, education.field_of_study, biology, Biochemical markers, FOXP3, Venous blood, Regulatory T cells, Middle Aged, Flow Cytometry, Prognosis, Inflamació, Phenotype, Citometria de fluxe, Marcadors bioquímics, Cytokines, Female, Inflammation Mediators, Uveitis, Tomography, Optical Coherence, lcsh:Immunologic diseases. Allergy, Adult, medicine.medical_specialty, CD3, Population, Immunology, Peripheral blood mononuclear cell, Macular Edema, 03 medical and health sciences, Young Adult, Predictive Value of Tests, Internal medicine, Humans, Interleukin 6, education, Macular edema, Aged, Inflammation, business.industry, Interleukin-6, biomarkers, medicine.disease, cytokines, 030104 developmental biology, Spain, biology.protein, lcsh:RC581-607, business, Biomarkers, 030215 immunology
Abstract

Purpose: To investigate whether systemic immune mediators and circulating regulatory T cells (Tregs) could be prognostic factors for anatomic outcomes in macular edema secondary to non-infectious uveitis (UME). Methods: Multicenter, prospective, observational, 12-month follow-up study of 60 patients with UME. Macular edema was defined as central subfield thickness (CST) > 300 μm measured with spectral domain optical coherence tomography (SD-OCT). Serum samples and peripheral blood mononuclear cells (PBMC) were obtained from venous blood extraction at baseline. Serum levels of IL-1β, IL-6, IL-8, IL-17, MCP-1, TNF-α, IL-10, and VEGF were determined by Luminex. Tregs population, defined as CD3+CD4+FoxP3+ in PBMC, was determined by flow cytometry. Main outcome measure was the predictive association between searched mediators and CST sustained improvement, defined as CST < 300 microns or a 20% CST decrease, at 6 months maintained until 12-months compared to baseline levels. Results: Multivariate logistic regression analysis showed an association between CST sustained improvement at 12 months follow-up and IL-6 and Tregs baseline levels. Higher IL-6 levels were associated with less events of UME improvement (OR: 0.67, 95% CI (0.45-1.00), P = 0.042), whereas higher levels of Tregs favored such improvement (OR: 1.25, 95% CI: 1.12-2.56, P = 0.049). Conclusions: Increased levels of Tregs and reduced levels of IL-6 in serum may be prognostic factors of sustained anatomical improvement in UME. These findings could enforce the opportunity to develop more efficient and personalized therapeutic approaches to improve long-term visual prognosis in patients with UME.

Published
2020

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