22 results on '"Maciel, Mônica"'
Search Results
2. Cheese Whey and Ricotta Whey for the Growth and Encapsulation of Endogenous Lactic Acid Bacteria
- Author
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Rabaioli Rama, Gabriela, Kuhn, Daniel, Beux, Simone, Jachetti Maciel, Mônica, and Volken de Souza, Claucia Fernanda
- Published
- 2020
- Full Text
- View/download PDF
3. Potential applications of dairy whey for the production of lactic acid bacteria cultures
- Author
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Rama, Gabriela Rabaioli, Kuhn, Daniel, Beux, Simone, Maciel, Mônica Jachetti, and Volken de Souza, Claucia Fernanda
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- 2019
- Full Text
- View/download PDF
4. Frequency of skin diseases in renal transplant recipients and patients with chronic kidney disease in a tertiary center: a cross-sectional study.
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Vieira, Érica Cristina, Marcolino, Milena Soriano, Guedes, Antônio Carlos Martins, Maciel, Mônica Maria Moreira Delgado, Santos, Wandilza Fátima dos, Pimentel, Luciana Consoli Fernandes, Gomes, Paulo Rodrigues, Bressan, Anita, Farah, Kátia de Paula, and Araújo, Marcelo Grossi
- Published
- 2024
- Full Text
- View/download PDF
5. Development of alginate-pectin microparticles with dairy whey using vibration technology: Effects of matrix composition on the protection of Lactobacillus spp. from adverse conditions
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Eckert, Camila, Agnol, Wendell Dall, Dallé, Danieli, Serpa, Vanessa Garcia, Maciel, Mônica Jachetti, Lehn, Daniel Neutzling, and Volken de Souza, Claucia Fernanda
- Published
- 2018
- Full Text
- View/download PDF
6. Encapsulation of Bioactive Ingredients by Extrusion with Vibrating Technology: Advantages and Challenges
- Author
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Fangmeier, Michele, Lehn, Daniel Neutzling, Maciel, Mônica Jachetti, and Volken de Souza, Claucia Fernanda
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- 2019
- Full Text
- View/download PDF
7. Population growth of the stored product pest Tyrophagus putrescentiae (Acari: Acaridae) on environmentally and medically important fungi
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da Silva, Guilherme Liberato, Esswein, Isadora Zanatta, Heidrich, Daiane, Dresch, Fabíola, Maciel, Mônica Jachetti, Pagani, Danielle Machado, Valente, Patrícia, Scroferneker, Maria Lúcia, Johann, Liana, Ferla, Noeli Juarez, and da Silva, Onilda Santos
- Published
- 2019
- Full Text
- View/download PDF
8. QUALITY OF COOLED RAW BOVINE MILK FROM MILK-PRODUCING PROPERTIES AND DAIRY INDUSTRIES IN THE TAQUARI VALLEY IN RIO GRANDE DO SUL, BRAZIL.
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Müller, Thais, Jachetti Maciel, Mônica, and Rempel, Claudete
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RAW milk ,DAIRY industry ,MILK yield ,DAIRY farms ,MILK storage ,SOMATIC cells ,MILK quality ,TEMPERATURE ,COLIFORMS - Abstract
Copyright of Environmental & Social Management Journal / Revista de Gestão Social e Ambiental is the property of Environmental & Social Management Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
9. Microbiota do leite de laticínios na Região Central do Rio Grande do Sul, Brasil
- Author
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Müller, Thais, Maciel, Mônica Jachetti, and Rempel, Claudete
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metagenomics ,Microrganismos ,metagenômica ,Microorganisms ,sequenciamento genético ,produção de leite ,genetic sequencing ,milk production ,milk quality ,qualidade do leite - Abstract
Milk is a rich food, source of several indispensable nutrients, much consumed by the population. Its quality and microbiota are influenced by several factors. The objective of the present study was to determine the microbiota of refrigerated raw milk and processed milk in dairy products in Vale do Taquari - RS, through genetic sequencing. Three types of milk were analyzed in two dairies in the region: raw refrigerated milk, which arrives at the dairies by means of tank trucks, pasteurized milk and milk treated by Ultra High Temperature (UHT). The determination of the milk microbiota was performed through sequencing of the 16S rRNA gene. The results showed that refrigerated raw milk has the highest number of microorganisms in the two dairy products, followed by pasteurized milk and milk sterilized by the UHT process, successively. Dairy processing 2 proved to be more efficient, especially for UHT treated milk, considerably reducing the microbiota. Eighty-seven species of the Bacteria Kingdom were identified and the samples showed considerable microbiological diversity. Psychrotrophic microorganisms such as Kurthia gibsonii were expressive in the samples. Lactic acid bacteria such as Streptococcus macedonicus were found in refrigerated raw milk and pasteurized milk and Streptococcus thermophilus in sterilized milk. Harmful species such as Bacillus cereus group, Aeromonas dhakensis and Acinetobacter haemolyticus were found in UHT treated milk from both dairy products, in addition to Aeromonas caviae, Enterobacter mori and Viridibacillus arenosi. RESUMO O leite é um alimento rico, fonte de diversos nutrientes indispensáveis, muito consumido pela população. A sua qualidade e a sua microbiota são influenciadas por diversos fatores. O objetivo do presente estudo foi determinar a microbiota do leite cru refrigerado e de leites processados em laticínios do Vale do Taquari - RS, por meio do sequenciamento genético. Foram analisados três tipos de leite em dois laticínios da região: leite cru refrigerado, que chega aos laticínios por meio dos caminhões-tanques, leite pasteurizado e leite esterilizado por Ultra High Temperature (UHT). A determinação da microbiota do leite foi realizada por meio do sequenciamento do gene 16S rRNA. Os resultados mostraram que o leite cru refrigerado possui a maior quantidade de microrganismos nos dois laticínios, seguido do leite pasteurizado e pelo leite tratado pelo processo UHT, sucessivamente. O processamento do Laticínio 2 mostrou-se mais eficiente, principalmente para o leite UHT, reduzindo consideravelmente a microbiota. Foram identificadas 87 espécies do Reino Bacteria e as amostras mostraram considerável diversidade microbiológica. Microrganismos psicrotróficos, como Kurthia gibsonii foram expressivos nas amostras. Bactérias ácido-láticas como Streptococcus macedonicus foram encontradas no leite cru refrigerado e no leite pasteurizado e Streptococcus termophilus, no leite esterilizado. Espécies nocivas como Bacillus cereus group, Aeromonas dhakensis e Acinetobacter haemolyticus foram encontrados no leite UHT de ambos os laticínios, além de Aeromonas caviae, Enterobacter mori and Viridibacillus arenosi.
- Published
- 2023
10. Characterization of technological and probiotic properties of indigenous Lactobacillus spp. from south Brazil
- Author
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Agostini, Camila, Eckert, Camila, Vincenzi, Angélica, Machado, Bruna Lenhardt, Jordon, Bruna Cristina, Kipper, João Pedro, Dullius, Anja, Dullius, Carlos Henrique, Lehn, Daniel Neutzling, Sperotto, Raul Antonio, Pozzobon, Adriane, Granada, Camille Eichelberger, Maciel, Mônica Jachetti, and Volken de Souza, Claucia Fernanda
- Published
- 2018
- Full Text
- View/download PDF
11. An Early and Sustained Inflammatory State Induces Muscle Changes and Establishes Obesogenic Characteristics in Wistar Rats Exposed to the MSG-Induced Obesity Model.
- Author
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Zazula, Matheus Felipe, Saraiva, Diego Francis, Theodoro, João Lucas, Maciel, Mônica, Sepulveda, Eliel Vieira dos Santos, Zanardini de Andrade, Bárbara, Boaretto, Mariana Laís, Maciel, Jhyslayne Ignácia Hoff Nunes, Bronczek, Gabriela Alves, Soares, Gabriela Moreira, Sagae Schneider, Sara Cristina, Bertolini, Gladson Ricardo Flor, Torrejais, Márcia Miranda, Ribeiro, Lucinéia Fátima Chasko, Fernandes, Luiz Claudio, and Naliwaiko, Katya
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LABORATORY rats ,INFLAMMATION ,MONOSODIUM glutamate ,OBESITY ,MYONEURAL junction - Abstract
The model of obesity induced by monosodium glutamate cytotoxicity on the hypothalamic nuclei is widely used in the literature. However, MSG promotes persistent muscle changes and there is a significant lack of studies that seek to elucidate the mechanisms by which damage refractory to reversal is established. This study aimed to investigate the early and chronic effects of MSG induction of obesity upon systemic and muscular parameters of Wistar rats. The animals were exposed to MSG subcutaneously (4 mg·g
−1 b.w.) or saline (1.25 mg·g−1 b.w.) daily from PND01 to PND05 (n = 24). Afterwards, in PND15, 12 animals were euthanized to determine the plasma and inflammatory profile and to assess muscle damage. In PND142, the remaining animals were euthanized, and samples for histological and biochemical analyses were obtained. Our results suggest that early exposure to MSG reduced growth, increased adiposity, and inducted hyperinsulinemia and a pro-inflammatory scenario. In adulthood, the following were observed: peripheral insulin resistance, increased fibrosis, oxidative distress, and a reduction in muscle mass, oxidative capacity, and neuromuscular junctions, increased fibrosis, and oxidative distress. Thus, we can conclude that the condition found in adult life and the difficulty restoring in the muscle profile is related to the metabolic damage established early on. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
12. Medicinal plants of the Unified Health System (Sistema Único de Saúde) with antifungal potential
- Author
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Maciel, Mônica Jachetti, Rempel, Claudete, Stroher, Amanda Luisa, Bergmann, Patrícia Caye, and Marmitt, Diorge Jônatas
- Abstract
Medicinal plants synthesize various secondary metabolites thatcan be used for therapeutic and antimicrobial purposes. In Brazil,the Unified Health System (SUS) offers several herbal medicines asan alternative in the treatment of various diseases. Considering theimportance of these plants in the production of chemicals that expandtherapeutic options and improve the health of SUS users, this reviewwas carried out to quantitatively determine the antifungal activity ofplants used as phytotherapeutics at RENAME. The selection of paperswas performed at three distinct stages: examining and choosing titlesrelated to antifungal action, reading the abstracts, and reading thewhole selected articles. This review selected 22 studies of interest;12 of them were conducted in Brazil and 10 were carried out in othercountries. The papers chosen tested the growth inhibitory effect ofplants against fungal species of agricultural and health importance,ranging from filamentous to yeast-like fungi, and Candida albicanswas the most tested species. The growth of 39 fungal species wereinhibited by some concentration of the extract used, with either anincrease or decrease in antifungal activity depending on the extractused. The most frequently analyzed plant was the species Schinusterebinthifolius Raddi., studied in seven papers. The results founddemonstrate the importance of analyzing medicinal plants andincorporating plant-based medicines in healthcare as an alternativesource of treatment, highlighting the need for studies that evaluatethe mechanisms action of their cytotoxicity and therapeutic effectsin the human body. As plantas medicinais produzem uma série de metabólitos secundáriosque podem ser usados para fins terapêuticos e antimicrobianos.No Brasil, o SUS disponibiliza uma série de medicamentos fitoterápicoscomo alternativa ao tratamento de diversas enfermidades.Considerando a importância da utilização dessas plantas na produçãode medicamentos que ampliem as opções terapêuticas e melhorema atenção à saúde de usuários do sistema, elaborou-se este estudode revisão com o objetivo de estimar quantitativamente a atividadeantifúngica das plantas utilizadas como fitoterápicos contidas naRENAME. A seleção de artigos deu-se por meio de três etapas distintas:leitura e escolha de títulos relacionados à ação antifúngica, leitura dosresumos e leitura na íntegra dos artigos selecionados. Esta revisãoselecionou 22 estudos de interesse, sendo 12 elaborados no Brasil e 10em outros países. Os artigos escolhidos testaram a ação inibitória dasplantas contra espécies de fungos de importância agrícola e sanitária,entre filamentosos e leveduriformes, sendo Candida albicans aespécie mais testada. Trinta e nove espécies foram inibidas por algumaconcentração do extrato utilizado, havendo aumento ou diminuição daatividade antifúngica conforme substância extratora utilizada. A plantamais analisada foi a espécie Schinus terebinthifolius Raddi., estudadaem sete artigos. Os resultados encontrados demonstram a importânciada análise de plantas medicinais e da incorporação de medicamentosà base de plantas como fonte alternativa de tratamento, salientandoa necessidade de estudos que demonstrem sua citotoxicidade emecanismos de ação terapêutica no organismo humano.
- Published
- 2021
13. Bacillus coagulans as an alternative to antibiotics in the performance and control of Salmonella Enteritidis in broilers.
- Author
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de Oliveira Lacerda, Dielly Inez, Patrícia Maciel, Mônica, Garcia de Araújo, Wagner Azis, Aiura, Felipe Shindy, da Silva Gonçalves, Deyvison, and Fernandes de Brito, Hebert
- Subjects
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BACILLUS (Bacteria) , *ANTIBIOTICS , *WEIGHT gain , *ANIMAL health , *PROBIOTICS , *MICROBIAL growth , *SALMONELLA enteritidis - Abstract
The use of antimicrobial growth promoters in broiler feed has been beneficial for improving performance and preventing diseases. However, the indiscriminate use of these products in the feed can result in the development of resistant bacteria, the accumulation of residues in the products, and an imbalance in the microflora of birds. Therefore, it is necessary to evaluate alternatives, such as beneficial microorganisms that improve microbial growth without affecting animal health and product quality. This research aimed to evaluate the supplementation with the probiotic Bacillus coagulans on the performance, carcass characteristics, and health of broilers from seven to 42 days. In total, 720 broilers were used, distributed in a randomized block design with six treatments and eight replicates. The evaluated treatments were as follows: Control ration (RC); PROB1 (Probiotic 400 g/t); PROB2 (Probiotic 400 g/t until 21 days and 200 g/t from 22 to 42 days); RC + antibiotic; RC + Salmonella inoculation; PROB1 + Salmonella inoculation. The treatments did neither influence feed intake, carcass yield, and cuts nor the incidence of injuries to the chest, hock, and footpad. Weight gain and feed conversion were better in birds that received antibiotic or probiotic diets. There was an incidence of Salmonella in the e challenges excreta at 42 days only in the treatment with challenge without adding probiotics. We conclude that the probiotic Bacillus coagulans can be used as an alternative to antibiotics in the diet of broilers as it facilitates similar performance and is efficient in the control of Salmonella Enteritidis. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
14. Sperm vitrification of Prochilodus brevis using Powder Coconut Water (ACP‐104) in association with different cryoprotectant concentrations.
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Almeida‐Monteiro, Priscila Silva, Pinheiro, Romulo Roberto Ribeiro, Oliveira‐Araújo, Mayara Setúbal, Sales, Yara Silvino, Nascimento, Renata Vieira, Nunes, Larissa Teixeira, Pereira, Vanessa Alves, Montenegro, Assis Rúbens, Melo‐Maciel, Mônica Aline Parente, and Salmito‐Vanderley, Carminda Sandra Brito
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COCONUT water ,VITRIFICATION ,SPERMATOZOA ,POWDERS ,ETHYLENE glycol ,LIQUID nitrogen - Abstract
The present study aims to evaluate the vitrification of the sperm of Prochilodus brevis. Six pools were made and diluted in media composed of 5% glucose (Experiment 1) or Powder Coconut Water (ACP‐104; Experiment 2) associated with dimethylsulphoxide (DMSO) or ethylene glycol (EG), or its association (DMSO + EG), in concentrations of 10%, 20% or 30%. Diluted samples were vitrified, stored in liquid nitrogen, devitrified after 15 days and evaluated for kinetics, morphology and plasmatic membrane (PMI) and sperm DNA (SDI) integrity. The experiments were conducted and evaluated independently of each other. No differences (p > 0.05) were found for the kinetics and morphology parameters in both experiments. The other parameters recorded interaction between cryoprotectants and their concentrations. The best PMI results (p < 0.05) were for glucose with 10% EG (19.75 ± 2.40) and ACP‐104 with 30% EG (46.92 ± 4.59). The best SDI rates (p < 0.05) were observed when glucose (45.43 ± 5.07) and ACP‐104 (71.83 ± 3.62) were associated with 30% EG. It is possible to conclude that vitrification has great potential for P. brevis sperm conservation; thus, we suggest using the association between ACP‐104 and 30% EG. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
15. Investigation of resistance of Salmonella spp. isolated from products and raw material of animal origin (swine and poultry)to antibiotics and disinfectants.
- Author
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MACIEL, Mônica Jachetti, MACHADO, Gustavo, and AVANCINI, Cesar Augusto Marchionatti
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DISINFECTION & disinfectants ,SALMONELLA enterica ,SODIUM hypochlorite ,ANTIBIOTICS ,SALMONELLA ,RAW materials - Abstract
Copyright of Revista Brasileira de Saúde e Produção Animal (RBSPA) is the property of Revista Brasileira de Saude e Producao Animal (RBSPA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
16. Occurrence of canine hip dysplasia, cranial cruciate ligament rupture and patellar luxation in dogs in a retrospective study of 100 orthopedic cases.
- Author
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Maciel, Mônica, de Oliveira Reusing, Mhayara Samile, Villanova Junior, José Ademar, Iobe Tasqueti, Ubirajara, and Henrique Weber, Saulo
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CANINE hip dysplasia ,CRUCIATE ligament injuries ,PATELLA dislocation ,ORTHOPEDICS ,LAMENESS in dogs - Abstract
Copyright of Revista Acadêmica: Ciência Animal is the property of Revista Academica: Ciencia Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
17. Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients.
- Author
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Delgado Maciel, Mônica Maria Moreira, das Graças Ceccato, Maria, da Silva Carvalho, Wânia, de Navarro, Pedro Daibert, de Paula Farah, Kátia, and de Miranda, Silvana Spindola
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KIDNEY transplantation ,TUBERCULIN test ,SKIN tests ,MYCOBACTERIAL diseases ,BIVARIATE analysis - Abstract
Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patients aged = 18 years who underwent renal transplantation at the Renal Transplant Center of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. We included renal transplant recipients who underwent the TST between January 2011 and July 2013. If the result of the first TST was negative, a second TST was administered. Bivariate and multivariate analyses using logistic regression were used to determine factors associated with positive TST results. Results: The sample included 216 patients. The prevalence of LTBI was 18.5%. In the multivariate analysis, history of contact with a tuberculosis case and preserved graft function (estimated glomerular filtration rate = 60 mL/min/1.73 m2) were associated with positive TST results. TST induration increased by 5.8% from the first to the second test, which was considered significant (p = 0.012). Conclusions: The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the first TST is negative. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
18. Microbiological analysis of surfaces in a surgical center: Identification and bacterial activity against antibiotics and disinfectant.
- Author
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Dresch, Fabíola, Rempel, Claudete, and Maciel, Mônica Jachetti
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ANTIBIOTICS ,DISINFECTION & disinfectants ,MICROBIAL sensitivity tests ,NOSOCOMIAL infections ,MEDICAL bacteriology - Abstract
Copyright of Revista Ciência e Natura is the property of Revista Ciencia e Natura and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
- Full Text
- View/download PDF
19. Alternative forced-molting methods in japanese quails.
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Batista SILVA, Daiane, Patrícia MACIEL, Mônica, Corrêia AROUCA, Cláudio Luiz, Shindy AIURA, Felipe, Martins SOUZA, Luiz Felipe, and Santana de MOURA, Vitor Hugo
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MOLTING ,QUAILS ,BIRD eggs ,BIRD food ,EGG quality ,AGRICULTURAL egg production - Abstract
Copyright of Revista Brasileira de Saúde e Produção Animal (RBSPA) is the property of Revista Brasileira de Saude e Producao Animal (RBSPA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
- Full Text
- View/download PDF
20. Prevalence of latent Mycobacterium tuberculosis infection in prisoners.
- Author
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de Navarro, Pedro Daibert, de Almeida, Isabela Neves, Kritski, Afrânio Lineu, Graças Ceccato, Maria das, Delgado Maciel, Mônica Maria, da Silva Carvalho, Wânia, and de Miranda, Silvana Spindola
- Subjects
MYCOBACTERIUM tuberculosis ,PRISONERS ,TUBERCULIN test ,MULTIVARIATE analysis ,INHALATION administration ,PRISON system ,DISEASES - Abstract
Objective: To determine the prevalence of and the factors associated with latent Mycobacterium tuberculosis infection (LTBI) in prisoners in the state of Minas Gerais, Brazil. Methods: This was a cross-sectional cohort study conducted in two prisons in Minas Gerais. Tuberculin skin tests were performed in the individuals who agreed to participate in the study. Results: A total of 1,120 individuals were selected for inclusion in this study. The prevalence of LTBI was 25.2%. In the multivariate analysis, LTBI was associated with self-reported contact with active tuberculosis patients within prisons (adjusted OR = 1.51; 95% CI: 1.05-2.18) and use of inhaled drugs (adjusted OR = 1.48; 95% CI: 1.03-2.13). Respiratory symptoms were identified in 131 (11.7%) of the participants. Serological testing for HIV was performed in 940 (83.9%) of the participants, and the result was positive in 5 (0.5%). Two cases of active tuberculosis were identified during the study period. Conclusions: Within the prisons under study, the prevalence of LTBI was high. In addition, LTBI was associated with self-reported contact with active tuberculosis patients and with the use of inhaled drugs. Our findings demonstrate that it is necessary to improve the conditions in prisons, as well as to introduce strategies, such as chest X-ray screening, in order to detect tuberculosis cases and, consequently, reduce M. tuberculosis infection within the prison system. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
21. Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients.
- Author
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Maciel MMMD, Ceccato MDG, Carvalho WDS, Navarro PD, Farah KP, and Miranda SS
- Subjects
- Adult, Aged, Brazil epidemiology, Cross-Sectional Studies, Female, Humans, Latent Tuberculosis diagnosis, Male, Middle Aged, Multivariate Analysis, Prevalence, Socioeconomic Factors, Tuberculin Test, Young Adult, Kidney Transplantation statistics & numerical data, Latent Tuberculosis epidemiology
- Abstract
Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results., Methods: This was a cross-sectional study of patients aged ≥ 18 years who underwent renal transplantation at the Renal Transplant Center of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. We included renal transplant recipients who underwent the TST between January 2011 and July 2013. If the result of the first TST was negative, a second TST was administered. Bivariate and multivariate analyses using logistic regression were used to determine factors associated with positive TST results., Results: The sample included 216 patients. The prevalence of LTBI was 18.5%. In the multivariate analysis, history of contact with a tuberculosis case and preserved graft function (estimated glomerular filtration rate ≥ 60 mL/min/1.73 m2) were associated with positive TST results. TST induration increased by 5.8% from the first to the second test, which was considered significant (p = 0.012)., Conclusions: The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the first TST is negative.
- Published
- 2018
- Full Text
- View/download PDF
22. Prevalence of latent Mycobacterium tuberculosis infection in prisoners.
- Author
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Navarro PD, Almeida IN, Kritski AL, Ceccato MD, Maciel MM, Carvalho WD, and Miranda SS
- Subjects
- Adult, Brazil epidemiology, Community-Acquired Infections diagnosis, Community-Acquired Infections epidemiology, Cross-Sectional Studies, Female, Humans, Illicit Drugs adverse effects, Latent Tuberculosis microbiology, Latent Tuberculosis transmission, Male, Prevalence, Tuberculin Test, Young Adult, Latent Tuberculosis epidemiology, Mycobacterium tuberculosis isolation & purification, Prisoners statistics & numerical data
- Abstract
Objective:: To determine the prevalence of and the factors associated with latent Mycobacterium tuberculosis infection (LTBI) in prisoners in the state of Minas Gerais, Brazil., Methods:: This was a cross-sectional cohort study conducted in two prisons in Minas Gerais. Tuberculin skin tests were performed in the individuals who agreed to participate in the study., Results:: A total of 1,120 individuals were selected for inclusion in this study. The prevalence of LTBI was 25.2%. In the multivariate analysis, LTBI was associated with self-reported contact with active tuberculosis patients within prisons (adjusted OR = 1.51; 95% CI: 1.05-2.18) and use of inhaled drugs (adjusted OR = 1.48; 95% CI: 1.03-2.13). Respiratory symptoms were identified in 131 (11.7%) of the participants. Serological testing for HIV was performed in 940 (83.9%) of the participants, and the result was positive in 5 (0.5%). Two cases of active tuberculosis were identified during the study period., Conclusions:: Within the prisons under study, the prevalence of LTBI was high. In addition, LTBI was associated with self-reported contact with active tuberculosis patients and with the use of inhaled drugs. Our findings demonstrate that it is necessary to improve the conditions in prisons, as well as to introduce strategies, such as chest X-ray screening, in order to detect tuberculosis cases and, consequently, reduce M. tuberculosis infection within the prison system., Objetivo:: Determinar a prevalência e os fatores associados à infecção latente por Mycobacterium tuberculosis (ILTB) em pessoas privadas de liberdade no Estado de Minas Gerais., Métodos:: Estudo de coorte transversal realizado em duas penitenciárias em Minas Gerais. Foi realizada a prova tuberculínica nos indivíduos que aceitaram participar do estudo., Resultados:: Foram selecionados 1.120 indivíduos para a pesquisa. A prevalência da ILTB foi de 25,2%. Na análise multivariada, a ILTB esteve associada com relato de contato com caso de tuberculose ativa dentro da penitenciária (OR ajustada = 1,51; IC95%: 1,05-2,18) e uso de drogas inaláveis (OR ajustada = 1,48; IC95%: 1,03-2,13). Foram identificados 131 pacientes sintomáticos respiratórios (11,7%). O teste anti-HIV foi realizado em 940 (83,9%) dos participantes, sendo positivo em 5 indivíduos (0,5%). Dois casos de tuberculose ativa foram identificados no período do estudo., Conclusões:: A prevalência de ILTB dentro das penitenciárias estudadas foi alta. Além disso, a ILTB estava associada ao relato de contato com casos de tuberculose e ao uso de drogas inaláveis. Nossos achados demonstram que é necessária a melhoria das condições de encarceramento e a utilização de outras estratégias, como a triagem por radiografia de tórax, para a descoberta de casos de tuberculose e redução da infecção pelo M. tuberculosis no sistema penitenciário.
- Published
- 2016
- Full Text
- View/download PDF
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