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2. Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90

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3. Discovery of a Novel Classof Highly Potent, Selective,ATP-Competitive, and Orally Bioavailable Inhibitors of the MammalianTarget of Rapamycin (mTOR).

4. Discovery of a Novel Seriesof Potent and Orally BioavailablePhosphoinositide 3-Kinase γ Inhibitors.

5. Synthesis of enantiopure five-carbon, stereodiads applicable for the preparation of the mycolactones.

8. An experimental and computational investigation of the enantioselective deprotonation of Boc-piperidine.