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3. Herbal drugs in chronic venous disease treatment: An update

Author

Bencsik, Tímea, Balázs, Viktória Lilla, Farkas, Ágnes, Csikós, Eszter, Horváth, Adrienn, Ács, Kamilla, Kocsis, Marianna, Doseděl, Martin, Fialová, Silvia Bittner, Czigle, Szilvia, Nagy, Milan, Tóth, Jaroslav, Protti, Michele, Mercolini, Laura, Mladěnka, Přemysl, Szentpéteri, József, and Horváth, Györgyi

Published
2024
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40. Natural products for the prevention and treatment of common cold and viral respiratory infections

Author

Mammari, Nour, Albert, Quentin, Devocelle, Marc, Kenda, Maša, farmacevtka, Kočevar Glavač, Nina, Sollner Dolenc, Marija, Mercolini, Laura, Tóth, Jaroslav, Nagy, Milan, pharmacist, Czigle, Szilvia, Varbanov, Mihayl, Laboratoire Lorrain de Chimie Moléculaire (L2CM), Institut de Chimie du CNRS (INC)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Biodiversité et Biotechnologie Fongiques (BBF), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Royal College of Surgeons in Ireland (RCSI), University of Ljubljana, University of Bologna/Università di Bologna, Comenius University in Bratislava, and This open-access review paper was supported by the Erasmus+ Programme of the EuropeanUnion, Key Action 2: Strategic Partnerships, project No. 2020-1-CZ01-KA203-078218, Open AccessEducational Materials on Naturally Occurring Molecules (OEMONOM).

Subjects
nalezljive bolezni, analgetiki, Zdravilne rastline, therapy, udc:582:615.322, infectious disease, pogosti prehladi, zdravilne rastline, common colds, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Analgetiki, herbal medicines, medicinal plants, common colds, therapy, infectious disease, analgesics, herbal medicines, analgesics, udc:582, zeliščna zdravila, terapija, zeliščna zdravila, pogosti prehladi, terapija, nalezljive bolezni, medicinal plants
Abstract

The common cold is generally considered a usually harmless infectious disease of the upper respiratory pathway, with mostly mild symptoms. However, it should not be overlooked, as a severe cold can lead to serious complications, resulting in hospitalization or death in vulnerable patients. The treatment of the common cold remains purely symptomatic. Analgesics as well as oral antihistamines or decongestants may be advised to relieve fever, and local treatments can clear the airways and relieve nasal congestion, rhinorrhea, or sneezing. Certain medicinal plant specialties can be used as therapy or as complementary self-treatment. Recent scientific advances discussed in more detail in this review have demonstrated the plant’s efficiency in the treatment of the common cold. This review presents an overview of plants used worldwide in the treatment of cold diseases. Nasl. z nasl. zaslona. Opis vira z dne 3. 5. 2023. Št. članka: 662. Bibliografija: str. 19-25. Abstract.

Published
2023
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41. Threat or treat: Exposure assessment and risk characterisation of chemical contaminants in soft drinks and chocolate bars in various Polish population age groups.

Author

Marincich, Lorenzo, Protti, Michele, Mandrioli, Roberto, Mercolini, Laura, and Woźniak, Łukasz

Subjects
POLISH people, CHOCOLATE drinks, SOFT drinks, HOT chocolate, AGE groups, SOFT drink industry, BEVERAGE industry
Abstract

In the frame of the European Food Risk Assessment (EU‐FORA) fellowship programme, two studies on chemical contaminants in food matrices were carried out in Warsaw, Poland, at the Department of Food Safety and Chemical Analysis, Institute of Agricultural and Food Biotechnology. The first study addressed health concerns about the dietary exposure to bisphenol A (BPA) contamination due to consumption of soft drink by Polish population. BPA is an organic additive used in the production of epoxy resins and polycarbonate plastics and because of this it is used in the internal coating of cans and in plastic bottle production. Depending on several factors, BPA can migrate from these materials to the soft drink and so, it can be ingested by consumers causing hormonal and reproductive disorders. To estimate the Polish population exposure to BPA, several soft drinks belonging to different brands were purchased from a supermarket in the city of Warsaw and analysed. The result of the analysis highlight that mean BPA exposure in the Polish population exceeds the tolerable daily intake proposed by the EFSA scientific opinion, raising health concerns. On the other hand, the second study, focused on cadmium exposure due to chocolate consumption by Polish population, did not raise any health concern. Cadmium is a heavy metal that naturally occurs in its inorganic form in the environment and its presence in chocolate derives only from the cocoa beans and not from contamination during processing. Its accumulation in the human body can create several adverse effects, including renal dysfunction and failure. To estimate the Polish population exposure to cadmium, several chocolate bars were purchased from a supermarket in the city of Warsaw and analysed. The results of the analysis show that cadmium exposure in the Polish population does not exceed the tolerable weekly intake proposed by the EFSA scientific opinion. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Characterisation and Quantification of Phenolic Compounds in Honeys from Sierra Nevada (Granada) †.

Author

Palma-Morales, Marta, Balzani, Alessandro, Huertas, Jesús R., Mercolini, Laura, and Rodríguez-Pérez, Celia

Subjects
HONEY, PHENOLS, HIGH performance liquid chromatography, ACID derivatives, BIOACTIVE compounds, PHENOLIC acids
Abstract

Some of the properties that have been attributed to honey are antioxidant, anti-inflammatory, and antimicrobial effects, especially due to its content of bioactive compounds, mainly phenolic compounds (PCs), whose content varies greatly depending on the variety, origin, agronomic conditions, harvest season, and climate. The aim of the present study is to characterise 21 honeys from Sierra Nevada (Granada). High-performance liquid chromatography coupled to quadrupole-time of flight mass spectrometry (HPLC-ESI-QTOF-MS) was used. Mass accuracy and true isotopic patterns in both MS and MS/MS spectra enabled the tentative identification of 58 PCs, including flavonoids, phenolic acids and derivatives. The average content of PCs was 83.01 ± 16.36 µg/g, with flavonoids accounting for more than 85%. The most abundant compounds were naringenin (16.88 ± 3.15 µg/g), pinocembrin (12.33 ± 2.92 µg/g), chrysin (12.21 ± 2.09 µg/g), carnosol (9.52 ± 2.90 µg/g), galangin (5.41 ± 1.68 µg/g), and apigenin (5.24 ± 0.89 µg/g). Due to this interesting composition, more studies are necessary to determine if the extreme environmental conditions of Sierra Nevada cause abiotic stress in the plants located there, fostering this concentration of PCs. [ABSTRACT FROM AUTHOR]

Published
2023
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49. Evaluation of the Antioxidant Capacity of Fruit Juices by Two Original Analytical Methods.

Author

Protti, Michele, Gualandi, Isacco, Zappoli, Sergio, Mandrioli, Roberto, Mercolini, Laura, and Tonelli, Domenica

Subjects
CARBON electrodes, OXIDANT status, FRUIT juices, HABER-Weiss reaction, SALICYLATES, HYDROGEN peroxide, RADICALS (Chemistry), VITAMIN C
Abstract

Two analytical methods previously developed by our groups were employed to estimate the antioxidant capacity of commercial fruit juices. The electrochemical method, which measures the scavenging activity of antioxidants towards OH radicals generated by both hydrogen peroxide photolysis and Fenton's reaction, is based on the recovery of the cyclic voltametric response of the redox probe Ru(NH3)63+ at a Glassy Carbon electrode modified with a thin film of an insulating polyphenol, in the presence of compounds with antioxidant properties. The values of the antioxidant capacity of the fruit juices are expressed as vitamin C equivalents/L. The chromatographic method is based on the generation of OH radicals via Fenton's reaction in order to test the inhibition of their formation in the presence of antioxidant compounds by monitoring salicylate aromatic hydroxylation derivatives as markers of •OH production, by means of HPLC coupled to coulometric detection. The results are expressed as the percentage of inhibition of •OH production in the presence of the tested juice compared to the control sample. When OH radicals are produced by Fenton's reaction, the antioxidant capacity of the juices, estimated by both methods, displays an analogous trend, confirming that they can be considered an alternative for measuring the ability of antioxidants to block OH radical formation. [ABSTRACT FROM AUTHOR]

Published
2023
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