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1. Identifying risk factors for blood culture negative infective endocarditis: An international ID-IRI study

Author

Filiz, Mine, Erdem, Hakan, Ankarali, Handan, Puca, Edmond, Ruch, Yvon, Santos, Lurdes, Fasciana, Teresa, Giammanco, Anna M., Ghanem-Zoubi, Nesrin, Argemi, Xavier, Hansmann, Yves, Guner, Rahmet, Tonziello, Gilda, Mazzucotelli, Jean-Philippe, Como, Najada, Kose, Sukran, Batirel, Ayse, Inan, Asuman, Tulek, Necla, Pekok, Abdullah Umut, Khan, Ejaz Ahmed, Iyisoy, Atilla, Meric-Koc, Meliha, Kaya-Kalem, Ayse, Martins, Pedro Palma, Hasanoglu, Imran, Silva-Pinto, André, Oztoprak, Nefise, Duro, Raquel, Almajid, Fahad, Dogan, Mustafa, Dauby, Nicolas, Gunst, Jesper Damsgaard, Tekin, Recep, Konopnicki, Deborah, Petrosillo, Nicola, Bozkurt, Ilkay, Al Ramahi, Jamal Wadi, Popescu, Corneliu, Balkan, Ilker Inanc, Ozer-Balin, Safak, Zupanc, Tatjana Lejko, Cascio, Antonio, Dumitru, Irina Magdalena, Erdem, Aysegul, Ersoz, Gulden, Tasbakan, Meltem, Ajamieh, Oday Abu, Sirmatel, Fatma, Florescu, Simin, Gulsun, Serda, Ozkaya, Hacer Deniz, Sari, Sema, Tosun, Selma, Avci, Meltem, Cag, Yasemin, Celebi, Guven, Sagmak-Tartar, Ayse, Karakus, Sumeyra, Sener, Alper, Dedej, Arjeta, Oncu, Serkan, Del Vecchio, Rosa Fontana, Ozturk-Engin, Derya, and Agalar, Canan

Published
2024
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3. Comparison of brucellar and tuberculous spondylodiscitis patients: results of the multicenter “Backbone-1 Study”

Author

Erdem, Hakan, Elaldi, Nazif, Batirel, Ayse, Aliyu, Sani, Sengoz, Gonul, Pehlivanoglu, Filiz, Ramosaco, Ergys, Gulsun, Serda, Tekin, Recep, Mete, Birgul, Balkan, Ilker Inanc, Sevgi, Dilek Yildiz, Giannitsioti, Efthymia, Fragou, Archontoula, Kaya, Selcuk, Cetin, Birsen, Oktenoglu, Tunc, DoganCelik, Aygul, Karaca, Banu, Horasan, Elif Sahin, Ulug, Mehmet, Inan, Asuman, Kaya, Safak, Arslanalp, Esra, Ates-Guler, Selma, Willke, Ayse, Senol, Sebnem, Inan, Dilara, Guclu, Ertugrul, Tuncer-Ertem, Gunay, Meric-Koc, Meliha, Tasbakan, Meltem, Senbayrak, Seniha, Cicek-Senturk, Gonul, Sırmatel, Fatma, Ocal, Gulfem, Kocagoz, Sesin, Kusoglu, Hulya, Guven, Tumer, Baran, Ali Irfan, Dede, Behiye, Yilmaz-Karadag, Fatma, Kose, Sukran, Yilmaz, Hava, Aslan, Gonul, ALGallad, D. Ashraf, Cesur, Salih, El-Sokkary, Rehab, Bekiroğlu, Nural, and Vahaboglu, Haluk

Published
2015
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4. Non-inferiority of Generic Tenofovir Disoproxil Fumarate/ Emtricitabine, Hivent® to Brand Name, Truvada® in HIV-Infected Patients

Author

İnan, Dilara, Öztoprak, Nefise, Kurtaran, Behice, Altuntaş Aydın, Özlem, Gümüşer, Fatma, Tabak, Fehmi, Bilge, Bilgenur, Meriç Koç, Meliha, Gencer, Serap, Öngüru, Pınar, Karabay, Oğuz, Köse, Şükran, Mete, Bilgül, and Gündüz, Alper

Abstract

Objective: Antiretroviral agents provided a significant improvement in HIV-related mortality. Generic drugs decrease the cost and provide easieraccess to treatment. However, there are concerns about efficacy and safety. We assessed non-inferiority of generic tenofovir disoproxil fumarate/emtricitabine, Hivent® to brand name drug, Truvada® in a retrospective cohort.Methods: Nine centers from Turkey were enrolled and the study included 457 patients followed up between May 2015 and April 2017 with Truvada®(n = 227) and Hivent® (n = 230) in combination with other antiretrovirals. Baseline characteristics were comparable in both groups. Demographiccharacteristics and laboratory values at baseline and during treatment were recorded. The primary endpoint was virologic response after 12 monthsof therapy, as determined by Snapshot algorithm from Food and Drug Administration (FDA). The sample size calculation was based on the primaryendpoint. Non-inferiority margin was taken as 10%.Results: After 12 months of therapy, both drugs provided a comparable decline in HIV-RNA: The values at baseline, 1st, 3rd, 6th, 9th, and 12th monthby Truvada® were 6.32, 3.62, 2.52, 3.53, 3.01, and 1.71 log10 copies/mL, respectively and values by Hivent® were 5.93, 3.89, 2.18, 1.72, 3.63, and1.54 log10 copies/mL, respectively (P = .33). Both drugs provided a comparable significant increase in CD4+ cell count: values By Truvada® were338, 412, 472, 497, 511, and 580 cells/mL, respectively and values by Hivent® were 337, 503, 531, 553, 644, and 660 cells/mL (P = .13). The rateand severity of side effects were similar and the changes in biochemical parameters were not different.Conclusion: This retrospective cohort study showed that Hiv

Published
2022

5. EACS Guidelines Version 9.1 Türkçe

Author

Meriç Koç, Meliha and MERİÇ KOÇ, MELİHA

Subjects
Meriç Koç M., Fırsatçı enfeksiyonlar, -EACS Guidelines Version 9.1 Türkçe-, Fehmi Tabak, Editör, İstanbul Medikal Yayıncılık, İstanbul, ss.88-99, 2019
Published
2019

7. Tetanus in adults: results of the multicenter ID-IRI study

Author

MERİÇ KOÇ, MELİHA and MERİÇ KOÇ, MELİHA

Subjects
results of the multicenter ID-IRI study.-, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, ss.1455-1462, 2017 [MERİÇ KOÇ M., -Tetanus in adults]
Published
2017

8. Are there enough nurses in Turkey? Results of the multicenter Karia study

Author

UYAN, AYŞE, durmuş, gül, sezak, nurbanu, pepe, fatmanur, ÖZTÜRK KAYGUSUZ, TÜRKKAN, akyol, firdevs, EROL, SERPİL, MERİÇ KOÇ, MELİHA, öncül, ahsen, aktaş, sabahat, ÇAŞKURLU, HÜLYA, ÇELEBİ, GÜVEN, EVİK, GÜLİZ, özger, hasan, harman, rezzan, TAŞBAKAN, MELTEM, ARDA, BİLGİN, ULUSOY, SERCAN, SİPAHİ, OĞUZ REŞAT, and MERİÇ KOÇ, MELİHA

Subjects
UYAN A., durmuş g., sezak n., pepe f., ÖZTÜRK KAYGUSUZ T., akyol f., EROL S., MERİÇ KOÇ M., öncül a., aktaş s., et al., -Are there enough nurses in Turkey? Results of the multicenter Karia study-, 27.ECCMID The European Congress of Clinical Microbiology and Infectious Diseases, 22 - 25 Nisan 2017
Published
2017

9. Utility of Rapid Antibody Test for Screening COVID-19 Among Healthcare Professionals.

Author

KAÇMAZ, Asiye Bahar, SÜMBÜL, Bilge, BOLUKÇU, Sibel, OKAY, Gülay, DURDU, Bülent, AKKOYUNLU, Yasemin, and MERİÇ KOÇ, Meliha

Subjects
MEDICAL personnel, COVID-19 testing, ANTIBODY titer, COVID-19, SYMPTOMS, TASTE disorders
Abstract

Copyright of Bezmialem Science is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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10. Malaria Prophylaxis and Vaccinations Among Turkish International Travelers: National Data, 2011-2016.

Author

OKAY, Gülay, AYAZOĞLU, Cemal, KAN, Osman, MERİÇ KOÇ, Meliha, and ASLAN, Turan

Subjects
VACCINATION, TRAVEL hygiene, MALARIA, MALARIA vaccines, TYPHOID fever, YELLOW fever
Abstract

Objective: The number of international travelers is increasing steadily. As a result, there is also an increase in travel-related infections. There is not enough data on travel vaccinations and prophylaxis in Turkey. The aim of this study is to create awareness and to guide national politics by presenting national data of Turkey. Methods: Travelers who took travel health services (THS) at travel health centers (THC) during 2011-2016 were included in the study. The data in the THC’s record system were examined for age, sex, purpose of travel, duration of stay, country of destination, learning source of THS, vaccinations and malaria prophylaxis. Results: During the study period, 162,023 people took THS. There was a 57% increase in the number of travelers who took THS in 2016 compared to 2011. There was no significant increase in the incidence of THS in Turkish travelers going abroad (0.33% and 0.43%, respectively in 2011 and 2016) (rs=0.36 p=0.47). The most common reason for traveling was business trips (79%), the most visited region was Africa (65.7%). The percentages of yellow fever vaccine, typhoid vaccine and malaria prophylaxis were 86.7%, 28.3%, and 44.7%, respectively. Conclusion: The main reason for travel was business and the most frequent destination was Africa. The number of travelers who took THS in travelers going abroad was very low in our country. It was concluded that awareness of travel-related health risks and preventive measures in the community should be increased. [ABSTRACT FROM AUTHOR]

Published
2019
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11. Hand Hygiene Compliance in Some Intensive Care Units of Turkey: Results of Multicentre Asklepeion Study.

Author

UYAN ÖNAL, Ayşe, AKSOY, Firdevs, AZAK, Emel, MERİÇ KOÇ, Meliha, ALKAN ÇEVİKER, Sevil, ATAMAN HATİPOĞLU, Çiğdem, GÖZÜKÜÇÜK, Ramazan, SEHMEN, Emine, UĞURLU, Kenan, ŞENOL, Güneş, DURMUŞ, Gül, ELMASLAR MERT, Habibe Tülin, ALAY, Handan, KOÇ, Filiz, ÇAĞLAYAN, Derya, DİKİŞ, Demet, BİLGİLİ KORKMAZ, Nilay, KÜÇÜKER, Nilgün Deniz, KEPELİ, Nurhayat, and ULUSOY, Behiye

Subjects
HAND care & hygiene, INTENSIVE care units, MEDICAL protocols, NOSOCOMIAL infection prevention
Abstract

Copyright of Mediterranean Journal of Infection, Microbes & Antimicrobials is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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12. Vaccine hesitancy and refusal among parents: An international ID-IRI survey

Author

Yakup Cag, Mohammad Emad Al Madadha, Handan Ankarali, Yasemin Cag, Kubra Demir Onder, Aysegul Seremet-Keskin, Filiz Kizilates, Rok Čivljak, Ghaydaa Shehata, Handan Alay, Sevil Alkan-Ceviker, Fatma Yilmaz-Karadag, Meliha Cagla-Sonmezer, Manar Ezzelarab Ramadan, Dumitru Irina Magdelena, Ljiljana Betica Radic, Jurica Arapovic, Fatma Kesmez-Can, Nagwa Mostafa El-Sayed, Oladapo Babatunde Campbell, Gulden Eser-Karlidag, Reham Khedr, Mehmet Emirhan Isik, Michael Mihailov Petrov, Roxana Cernat, Umran Erturk, Yesim Uygun-Kizmaz, Eva Huljev, Fatma Amer, Mehmet Resat Ceylan, Andrea Marino, Gulnur Kul, Tuba Damar-Cakirca, Yara Mohsen Khalaf, Arzu Cennet Isik, Olumuyiwa Elijah Ariyo, Ismail Necati Hakyemez, Rezaul Karim Ripon, Abdorrahim Afkhamzadeh, Emine Kubra Dindar-Demiray, Osasona Oluwadamilola Gideon, Maya Belitova, Mustafa Altindis, Rehab El-Sokkary, Recep Tekin, Mohammed Ahmed Garout, Joanna Zajkowska, Farhan Fazal, Muhammed Bekcibasi, Mirsada Hukic, Summiya Nizamuddin, Serkan Surme, Ricardo Fernandez, Amani El-Kholy, Nasim Akhtar, Saadia Ijaz, Andrea Cortegiani, Meliha Meric-Koc, Hakan Hasman, Agah Victor Maduka, Jehan Ali ElKholy, Sema Sari, Mumtaz Ali Khan, Yasemin Akin, Sukran Kose, Hakan Erdem, MERİÇ KOÇ, MELİHA, Cag, Yakup, Al Madadha, Mohammad Emad, Ankarali, Handan, Cag, Yasemin, Demir Onder, Kubra, Seremet-Keskin, Aysegul, Kizilates, Filiz, Čivljak, Rok, Shehata, Ghaydaa, Alay, Handan, Alkan-Ceviker, Sevil, Yilmaz-Karadag, Fatma, Cagla-Sonmezer, Meliha, Ezzelarab Ramadan, Manar, Magdelena, Dumitru Irina, Radic, Ljiljana Betica, Arapovic, Jurica, Kesmez-Can, Fatma, El-Sayed, Nagwa Mostafa, Campbell, Oladapo Babatunde, Eser-Karlidag, Gulden, Khedr, Reham, Isik, Mehmet Emirhan, Petrov, Michael Mihailov, Cernat, Roxana, Erturk, Umran, Uygun-Kizmaz, Yesim, Huljev, Eva, Amer, Fatma, Ceylan, Mehmet Resat, Marino, Andrea, Kul, Gulnur, Damar-Cakirca, Tuba, Khalaf, Yara Mohsen, Isik, Arzu Cennet, Ariyo, Olumuyiwa Elijah, Hakyemez, Ismail Necati, Ripon, Rezaul Karim, Afkhamzadeh, Abdorrahim, Dindar-Demiray, Emine Kubra, Gideon, Osasona Oluwadamilola, Belitova, Maya, Altindis, Mustafa, El-Sokkary, Rehab, Tekin, Recep, Garout, Mohammed Ahmed, Zajkowska, Joanna, Fazal, Farhan, Bekcibasi, Muhammed, Hukic, Mirsada, Nizamuddin, Summiya, Surme, Serkan, Fernandez, Ricardo, El-Kholy, Amani, Akhtar, Nasim, Ijaz, Saadia, Cortegiani, Andrea, Meric-Koc, Meliha, Hasman, Hakan, Maduka, Agah Victor, ElKholy, Jehan Ali, Sari, Sema, Khan, Mumtaz Ali, Akin, Yasemin, Kose, Sukran, and Erdem, Hakan

Subjects
Male, Parents, Health Knowledge, Attitudes, Practice, An international ID-IRI survey-, JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, cilt.16, sa.6, ss.1081-1088, 2022 [Cag Y., Al Madadha M. E. , ANKARALI H., ÇAĞ Y., Onder K. D. , Seremet-Keskin A., Kizilates F., Civljak R., Shehata G., ALAY H., et al., -Vaccine hesitancy and refusal among parents], Vaccination, General Medicine, Patient Acceptance of Health Care, Microbiology, Communicable Diseases, parent, Infectious Diseases, Cross-Sectional Studies, Virology, Surveys and Questionnaires, vaccine refusal, Humans, Parasitology, Female, Vaccination Hesitancy, Child, Vaccine hesitancy
Abstract

Introduction:Although vaccines are the safest and most effective means to prevent and control infectious diseases, the increasing rate of vaccine hesitancy and refusal (VHR) has become a worldwide concern. We aimed to find opinions of parents on vaccinating their children and contribute to available literature in order to support the fight against vaccine refusal by investigating the reasons for VHR on a global scale.Methodology:In this international cross-sectional multicenter study conducted by the Infectious Diseases International Research Initiative (ID-IRI), a questionnaire consisting of 20 questions was used to determine parents' attitudes towards vaccination of their children.Results:Four thousand and twenty-nine (4,029) parents were included in the study and 2,863 (78.1%) were females. The overall VHR rate of the parents was found to be 13.7%. Nineteen-point three percent (19.3%) of the parents did not fully comply with the vaccination programs. The VHR rate was higher in high-income (HI) countries. Our study has shown that parents with disabled children and immunocompromised children, with low education levels, and those who use social media networks as sources of information for childhood immunizations had higher VHR rates (p < 0.05 for all).Conclusions:Seemingly all factors leading to VHR are related to training of the community and the sources of training. Thus, it is necessary to develop strategies at a global level and provide reliable knowledge to combat VHR.Keywords:Vaccine hesitancy; parents; vaccine refusal.Copyright (c) 2022 Yakup Cag, Mohammad Emad al Madadha, Handan Ankarali, Yasemin Cag, Kubra Demir Onder, Aysegul Seremet-Keskin, Filiz Kizilates, Rok Civljak, Ghaydaa Shehata, Handan Alay, Sevil Alkan-Ceviker, Fatma Yilmaz-Karadag, Meliha Cagla-Sonmezer, Manar Ezzelarab Ramadan, Dumitru Irina Magdelena, Ljiljana Betica Radic, Jurica Arapovic, Fatma Kesmez-Can, Nagwa Mostafa El-Sayed, Oladapo Babatunde Campbell, Gulden Eser-Karlidag, Reham Khedr, Mehmet Emirhan Isik, Michael Mihailov Petrov, Roxana Cernat, Umran Erturk, Yesim Uygun-Kizmaz, Eva Huljev, Fatma Amer, Mehmet Resat Ceylan, Andrea Marino, Gulnur Kul, Tuba Damar-Cakirca, Yara Mohsen Khalaf, Arzu Cennet Isik, Olumuyiwa Elijah Ariyo, Ismail Necati Hakyemez, Rezaul Karim Ripon, Abdorrahim Afkhamzadeh, Emine Kubra Dindar-Demiray, Osasona Oluwadamilola Gideon, Maya Belitova, Mustafa Altindis, Rehab El-Sokkary, Recep Tekin, Mohammed Ahmed Garout, Joanna Zajkowska, Farhan Fazal, Muhammed Bekcibasi, Mirsada Hukic, Summiya Nizamuddin, Serkan Surme, Ricardo Fernandez, Amani El-Kholy, Nasim Akhtar, Saadia Ijaz, Andrea Cortegiani, Meliha Meric-Koc, Hakan Hasman, Agah Victor Maduka, Jehan Ali ElKholy, Sema Sari, Mumtaz Ali Khan, Yasemin Akin, Sukran Kose, Hakan Erdem.

Published
2022

13. Impact of switching to E/C/F/TAF on lipid profile and renal function in HIV-infected patients

Author

Mete, B., Gunduz, A., Zerdali, E., Senoglu, S., BOLUKÇU, SİBEL, Nakir, I. Yilmaz, Karaosmanoglu, H. Kumbasar, Koc, MELİHA, Bilge, B., Dokmetas, I., Tabak, F., and MERİÇ KOÇ, MELİHA

Subjects
Mete B., Gunduz A., Zerdali E., Senoglu S., BOLUKÇU S., Nakir I. Y. , Karaosmanoglu H. K. , Koc M., Bilge B., Dokmetas I., et al., -Impact of switching to E/C/F/TAF on lipid profile and renal function in HIV-infected patients-, HIV MEDICINE, cilt.20, ss.87-88, 2019
Published
2019

14. Portraying infective endocarditis

Author

Ilker Inanc Balkan, Najada Como, André Silva-Pinto, Antonio Cascio, Canan Agalar, Meliha Meric-Koc, Tatjana Lejko Zupanc, Oday Abu Ajamieh, Simin Aysel Florescu, Selma Tosun, Meltem Taşbakan, Asuman Inan, Rosa Fontana Del Vecchio, Edmond Puca, Güven Çelebi, Ayse Sagmak-Tartar, Abdullah Umut Pekok, Yasemin Cag, Gülden Ersöz, Sumeyra Karakus, Safak Ozer-Balin, Jamal Wadi, Sukran Kose, Yves Hansmann, Hacer Deniz Ozkaya, Nefise Oztoprak, Hakan Erdem, Serkan Oncu, Jesper Damsgaard Gunst, Yvon Ruch, Aysegul Erdem, Gilda Tonziello, Ayse Batirel, Rahmet Guner, Irina Magdalena Dumitru, Lurdes Santos, Raquel Duro, Nesrin Ghanem-Zoubi, Arjeta Dedej, Serda Gulsun, Mustafa Dogan, Necla Tulek, Alper Şener, Pedro Palma Martins, Ilkay Bozkurt, Deborah Konopnicki, Fatma Sirmatel, Xavier Argemi, Meltem Avci, Fahad Almajid, Recep Tekin, Nicola Petrosillo, Corneliu Petru Popescu, Ayse Kaya-Kalem, Imran Hasanoglu, Atilla Iyisoy, Jean Philippe Mazzucotelli, Ejaz Ahmed Khan, Sema Sarı, Derya Ozturk-Engin, Nicolas Dauby, Erdem H., Puca E., Ruch Y., Santos L., Ghanem-Zoubi N., Argemi X., Hansmann Y., Guner R., Tonziello G., Mazzucotelli J.-P., Como N., Kose S., Batirel A., Inan A., Tulek N., Pekok A.U., Khan E.A., Iyisoy A., Meric-Koc M., Kaya-Kalem A., Martins P.P., Hasanoglu I., Silva-Pinto A., Oztoprak N., Duro R., Almajid F., Dogan M., Dauby N., Gunst J.D., Tekin R., Konopnicki D., Petrosillo N., Bozkurt I., Wadi J., Popescu C., Balkan I.I., Ozer-Balin S., Zupanc T.L., Cascio A., Dumitru I.M., Erdem A., Ersoz G., Tasbakan M., Ajamieh O.A., Sirmatel F., Florescu S., Gulsun S., Ozkaya H.D., Sari S., Tosun S., Avci M., Cag Y., Celebi G., Sagmak-Tartar A., Karakus S., Sener A., Dedej A., Oncu S., Del Vecchio R.F., Ozturk-Engin D., Agalar C., Virulence Bactérienne Précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe, Université de Strasbourg (UNISTRA), Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aiguë et subaiguë, Nanomédecine Régénérative (NanoRegMed), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), MERİÇ KOÇ, MELİHA, İÜC, Cerrahpaşa Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Uşak Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Sırmatel, Fatma, and OMÜ

Subjects
Male, Internationality, Aucun, Infective endocarditi, medicine.disease_cause, Medical microbiology, 80 and over, Blood culture, Hospital Mortality, Aged, 80 and over, medicine.diagnostic_test, biology, Endocarditis, Bacterial, General Medicine, Sciences bio-médicales et agricoles, Middle Aged, Staphylococcal Infections, Sciences du Vivant [q-bio]/Microbiologie et Parasitologie, Viridans Streptococci, Catheter, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Staphylococcus aureus, Infective endocarditis, Aortic Valve, Mitral Valve, Female, Microbiology (medical), Adult, medicine.medical_specialty, Prosthesis-Related Infections, Adolescent, aureus, Young Adult, Internal medicine, medicine, Humans, results of multinational ID-IRI study-, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, cilt.38, ss.1753-1763, 2019 [Erdem H., Puca E., Ruch Y., Santos L., Ghanem-Zoubi N., Argemi X., Hansmann Y., Guner R., Tonziello G., Mazzucotelli J., et al., -Portraying infective endocarditis], Prosthetic, Aged, Native Valve Endocarditis, Bacteria, business.industry, Endocarditis, Bacterial, medicine.disease, biology.organism_classification, S. aureus, Viridans streptococci, business, Native
Abstract

Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients had pacemaker lead endocarditis, and 1 patient had catheter port endocarditis. Eighteen percent of NVE patients were hospital-acquired. PVE patients were classified as early-onset in 24.9%. A total of 385 (44.4%) patients had major embolic events, most frequently to the brain (n = 227, 26.3%). Blood cultures yielded pathogens in 766 (88.4%). In 101 (11.6%) patients, blood cultures were negative. Molecular testing of vegetations disclosed pathogens in 65 cases. Overall, 795 (91.7%) endocarditis patients had any identified pathogen. Leading pathogens (Staphylococcus aureus (n = 267, 33.6%), Streptococcus viridans (n = 149, 18.7%), enterococci (n = 128, 16.1%), coagulase-negative staphylococci (n = 92, 11.6%)) displayed substantial resistance profiles. A total of 132 (15.2%) patients had cardiac abscesses; 693 (79.9%) patients had left-sided endocarditis. Aortic (n = 394, 45.4%) and mitral valves (n = 369, 42.5%) were most frequently involved. Mortality was more common in PVE than NVE (NVE (n = 101, 16%), PVE (n = 49, 22.9%), p = 0.042)., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2019

15. Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?: Results of the Phokai Study

Author

Türkkan Öztürk Kaygusuz, Oğuz Sipahi, Mustafa Dogan, Erdem Güven, Feride Kocak, S Alkan Ceviker, Derya Caglayan, Firdevs Aksoy, Yeşim Kürekçi, Metin Arslan, G Evik, Güven Çelebi, S Cagan Aktas, N Dogan, Ramazan Gözüküçük, Fatih Koc, Kenan Ugurlu, Burak Özdemir, Selçuk Özger, ME Isik, Ayşe Uyan, Sema Sarı, Fethiye Akgül, Rezan Harman, Handan Alay, B Isik, Hilal Sipahi, S Ozkoren Calik, Ilknur Esen Yildiz, Gunes Senol, Kevser Ozdemir, Gül Durmuş, Meliha Meriç Koç, HT Elmaslar Mert, Bilgin Arda, Nefise Oztoprak, Hamza Erdogan, Nurbanu Sezak, Aslıhan Demirel, A Ozgultekin, Tansu Yamazhan, Mehmet Uçar, Sercan Ulusoy, EK Dindar Demiray, G Unsal, Ahsen Oncul, [Uyan, Ayse -- Yamazhan, Tansu -- Arda, Bilgin -- Ulusoy, Sercan -- Sipahi, Oguz Resat] Ege Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Izmir, Turkey -- [Durmus, Gul] Bursa Yuksek Ihtisas Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Bursa, Turkey -- [Sezak, Nurbanu] Izmir Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Izmir, Turkey -- [Ozdemir, Burcu] Ankara Numune Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Kaygusuz, Turkkan] Elazig Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Elazij, Turkey -- [Oztoprak, Nefise] Antalya Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Antalya, Turkey -- [Ozdemir, Keyser] Pamukkale Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Denizli, Turkey -- [Aksoy, Firdevs] Karadeniz Tech Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Trabzon, Turkey -- [Ozgultekin, Asu] Haydarpasa Numune Training & Res Hosp, Clin Anesthesiol & Intens Care, Istanbul, Turkey -- [Koc, Meliha Meric] Kocaeli Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Kocaeli, Turkey -- [Oncul, Ahsen] Sisli Etfal Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Cagan Aktas, Sabahat] Dr Lutfi Kirdar Kartal Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Isik, Burcu] Istanbul Medeniyet Univ, Goztepe Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Celebi, Giiven] Bulent Ecevit Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Zonguldak, Turkey -- [Evik, Guliiz] Mersin Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Mersin, Turkey -- [Ozger, Selcuk] Dr Ersin Arslan Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Harman, Rezan] Private Sani Konukoglu Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Dindar Demiray, Emine Kubra] Celal Bayar Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Manisa, Turkey -- [Ozkoren Calik, Sebnem] Izmir Bozyaka Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Alkan Ceviker, Sevil] Balikesir State Hosp, Clin Infect Dis & Clin Microbiol, Balikesir, Turkey -- [Yildiz, Ilknur Esen] Recep Tayyip Erdogan Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Rize, Turkey -- [Isik, Mehmet Emirhan] Kartal Kosuyolu Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Senol, Gunes] Dr Suat Seren Chest Dis & Chest Surg Training & R, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Sari, Sema] Turkiye Yuksek Ihtisas Hosp, Clin Intens Care, Ankara, Turkey -- [Dogan, Mustafa] Corlu State Hosp, Clin Infect Dis & Clin Microbiol, Tekirdag, Turkey -- [Ugurlu, Kenan] 25 Aralik & State Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Arslan, Mustafa] Amasya Univ, Sabuncuoglu Serefeddin Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Amasya, Turkey -- [Akgul, Fethiye] Batman State Hosp, Clin Infect Dis & Clin Microbiol, Batman, Turkey -- [Koc, Filiz] Kecioren Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Kurekci, Yeim] Arnavutkoy State Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Caglayan, Derya] Torbali State Hosp, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Ucar, Mehmet] Usak Med Pk Hosp, Clin Infect Dis & Clin Microbiol, Usak, Turkey -- [Gozukucuk, Ramazan] Private Hisar Intercontinental Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Elmaslar Mert, Habibe Tulin] Ardahan State Hosp, Clin Infect Dis & Clin Microbiol, Ardahan, Turkey -- [Alay, Handan] Nenehatun Obstet & Gynecol Hosp, Clin Infect Dis & Clin Microbiol, Erzurum, Turkey -- [Erdogan, Haluk] Baskent Univ, Alanya Med & Res Ctr, Dept Infect Dis & Clin Microbiol, Antalya, Turkey -- [Demirel, Aslihan] Istanbul Bilim Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Dogan, Nilgun] TOBB Univ Econ & Technol Hosp, Hosp Infect Control Comm, Ankara, Turkey -- [Kocak, Funda] Basaksehir State Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Guven, Emre] Beytepe Murat Erdi Eker State Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Unsal, Guieser] Bozok Univ, Hosp Infect Control Comm, Fac Med, Yozgat, Turkey -- [Sipahi, Hilal] Bornova Publ Hlth Ctr, Izmir, Turkey, MERİÇ KOÇ, MELİHA, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Yıldız, İlknur Esen, Zonguldak Bülent Ecevit Üniversitesi, and Ege Üniversitesi

Subjects
Microbiology (medical), SOAP, computer.internet_protocol, intensive care units, lcsh:Medicine, alcohol based disinfectants, Alcohol based disinfectants, Soap, lcsh:Infectious and parasitic diseases, paper towel, Intensive care, medicine, nosocomial infections, lcsh:RC109-216, Results of the Phokai Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.7, 2018 [Uyan A., Durmus G., Sezak N., Ozdemir B., Kaygusuz T., Oztoprak N., Ozdemir K., AKSOY F., Ozgultekin A., Koc M., et al., -Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?], Intensive care units, General Immunology and Microbiology, lcsh:R, Paper towel, medicine.disease, Infectious Diseases, Medical emergency, Business, computer
Abstract

Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products., Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016)., Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p, Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well.

Published
2018

16. Türkiye’deki yoğun bakım ünitelerinde hemşire işgücü yeterli mi? Çok merkezli karia çalışmasının sonuçları

Author

Alpay Ari, Yeşim Kürekçi, Fatmanur Pepe, Handan Alay, Funda Kocak, Mehmet Uçar, Selçuk Özger, Türkkan Öztürk Kaygusuz, Serpil Erol, Rezan Harman, Ramazan Gözüküçük, Güleser Ünsal, Oğuz Reşat Sipahi, Sema Sarı, Ilknur Esen Yildiz, Gül Durmuş, Meliha Meriç Koç, Nefise Oztoprak, Kenan Uğurlu, Aslıhan Demirel, Sevil Alkan Çeviker, Şirin Menekşe, Güven Çelebi, Nilgün Doğan, Ayşe Uyan, Meltem Taşbakan, Firdevs Aksoy, Nurbanu Sezak, Mustafa Doğan, Hilal Sipahi, Pınar Firat, Kevser Ozdemir, Gunes Senol, Sercan Ulusoy, Bilgin Arda, Kübra Demiray, Derya Çağlayan, İrem Akdemir, Sabahat Çağan Aktaş, Ahsen Oncul, Mustafa Arslan, Haluk Erdoğan, Hulya Caskurlu, Özlem Kandemir, Habibe Tülin Elmaslar Mert, Emre Güven, Ege Üniversitesi, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Yıldız, İlknur Esen, Zonguldak Bülent Ecevit Üniversitesi, and MERİÇ KOÇ, MELİHA

Subjects
Microbiology (medical), Healthcare associated infections, Infection control, infection, healthcare-associated infections, intensive care infections, health care facilities, manpower, and services, education, lcsh:Medicine, Healthcare-associated infections, lcsh:Infectious and parasitic diseases, Nursing, Infection control practitioner, Intensive care, Medicine, lcsh:RC109-216, Intensive care infections, integumentary system, General Immunology and Microbiology, business.industry, lcsh:R, infection control practitioner, Infectious Diseases, Workforce, Uyan A., Durmus G., Sezak N., Pepe F., Kaygusuz T., Oztoprak N., Ozdemir K., AKSOY F., Erol S., Koc M., et al., -Is Nurse Workforce Sufficient in Intensive Care Units in Turkey. Results of the Multicenter Karia Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.6, 2017, business, Infection
Abstract

Introduction: In this multicenter study, we analysed the magnitude of healthcare worker (HCW) [infection control practitioner (ICP), nurses and others] workforce in hospitals participated in the study., Materials and Methods: This study was performed in 41 hospitals (with intensive care units-ICU) located in 22 cities from seven regions of Turkey. We analysed the ICP workforce, nursing and auxiliary HCW (AHCW) workforce in ICUs, number of ICU beds and occupied beds in four different days [two of which were in summer during the vacation time (August 27 and 31, 2016) and two others in autumn (October 12 and 15, 2016)]. The Turkish Ministry of Health (TMOH) requires two patients per nurse in level 3 ICUs, three patients per nurse in level 2 ICUs and five patients per nurse in level 1 ICUs. There is no standardization for the number of AHCW in ICUs. Finally, one ICP per 150 hospital beds is required by TMOH., Results: The total number of ICUs, ICU beds and ICPs were 214, 2377 and 111, respectively in he 41 participated centers. The number ICPs was adequate only in 12 hospitals. The percentage of nurses whose working experience was 2. The number of patients per other HCW was minimum 3.75 and maximum 4.89 on weekdays and on day shift while it was minimum 5.02 and maximum 7.7 on weekends or on night shift. When we compared the number of level 1, 2 and 3 ICUs with adequate nursing workforce vs inadequate nursing workforce, the p value was, Conclusion: Our data suggest that ICP workforce is inadequate in Turkey. Besides, HCW workforce is inadequate and almost 1/4 of nurses are relatively inexperienced especially in level 3 ICUs. Turkish healthcare system should promptly make necessary arrangements for adequate HCW staffing.

Published
2017

17. Surgical site infection rates in 16 cities in Turkey: findings of the International Nosocomial Infection Control Consortium (INICC)

Author

Ahmet Şahin, Iftihar Koksal, Gaye Usluer, Hülya Sungurtekin, Tanıl Kendirli, Selçuk Kaya, Eylul Gumus, Gürdal Yýlmaz, Mehmet Faruk Geyik, Ertugrul Guclu, Nurettin Erben, Tuna Demirdal, Tuncer Haznedaroglu, Huseyin Turgut, Levent Gorenek, Erdal Ince, Melek Güneş, Hava Yilmaz, Necdet Kuyucu, Suzan Sacar, Alper Şener, Oguz Dursun, Nefise Oztoprak, Ahmet Dilek, Fatma Sirmatel, Ergin Çiftçi, Meliha Meric, Gulsume Kaya, Mustafa Sunbul, Metin Otkun, Emel Azak, Fatma Ülger, Gülden Ersöz, Yunus Gürbüz, Ayşe Willke, Sehnaz Kaya, Hakan Leblebicioglu, Oral Oncul, Davut Ozdemir, Nevin Taşyapar, Ali Acar, Ediz Tutuncu, Zeynep Kaya, Doğaç Uğurcan, Oguz Karabay, Victor D. Rosenthal, Fazilet Duygu, Saban Esen, Ali Kaya, Ata Nevzat Yalcin, Hülya Ulusoy, Gunes Senol, Adem Karbuz, Turan Aslan, Özge Turhan, Selvi Erdogan, Cengiz Uzun, Ilhan Ozgunes, Leblebicioglu, H, Erben, N, Rosenthal, VD, Sener, A, Uzun, C, Senol, G, Ersoz, G, Demirdal, T, Duygu, F, Willke, A, Sirmatel, F, Oztoprak, N, Koksal, I, Oncul, O, Gurbuz, Y, Guclu, E, Turgut, H, Yalcin, AN, Ozdemir, D, Kendirli, T, Aslan, T, Esen, S, Ulger, F, Dilek, A, Yilmaz, H, Sunbul, M, Ozgunes, I, Usluer, G, Otkun, M, Kaya, A, Kuyucu, N, Kaya, Z, Meric, M, Azak, E, Yylmaz, G, Kaya, S, Ulusoy, H, Haznedaroglu, T, Gorenek, L, Acar, A, Tutuncu, E, Karabay, O, Kaya, G, Sacar, S, Sungurtekin, H, Ugurcan, D, Turhan, O, Gumus, E, Dursun, O, Geyik, MF, Sahin, A, Erdogan, S, Ince, E, Karbuz, A, Ciftci, E, Tasyapar, N, Gunes, M, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Güçlü, Ertuğrul, MERİÇ KOÇ, MELİHA, and Ondokuz Mayıs Üniversitesi

Subjects
Turkey, Epidemiology, Surgical wound infection, Health careeassociated infection, Turkey (republic), Cohort Studies, hip prosthesis, Nosocomial infection, Prospective Studies, hospital, Prospective cohort study, Health Policy, craniotomy, clinical trial, cohort analysis, Hospitals, hospital patient, Infectious Diseases, Cohort, Surgical site infection, Cohort study, prospective study, medicine.medical_specialty, Health care-associated infection, prevalence, education, infection rate, surgical infection, Article, Developing countries, coronary artery bypass graft, Internal medicine, medicine, Humans, Hospital infection, human, Cities, cesarean section, business.industry, Public Health, Environmental and Occupational Health, findings of the International Nosocomial Infection Control Consortium (INICC)-, AMERICAN JOURNAL OF INFECTION CONTROL, cilt.43, ss.48-52, 2015 [Leblebicioglu H., Erben N., ROSENTHAL V. D. , ŞENER A., UZUN C., SENOL G., Ersoz G., Demirdal T., DUYGU F., Willke A., et al., -Surgical site infection rates in 16 cities in Turkey], Nosocomial infection control, Confidence interval, shunting, Surgery, Clinical trial, multicenter study, city, business
Abstract

Yalcin, Ata Nevzat/0000-0002-7243-7354; dursun, oguz/0000-0001-5482-3780; Oncul, Oral/0000-0002-1681-1866; Leblebicioglu, Hakan/0000-0002-6033-8543; demirdal, tuna/0000-0002-9046-5666; Ciftci, Ergin/0000-0002-4955-160X; Erben, Nurettin/0000-0003-0373-0132; Kendirli, Tanil/0000-0001-9458-2803; Acar, Ali/0000-0003-2008-5112; Geyik, Mehmet Faruk/0000-0002-0906-0902; Dursun, Oguz/0000-0001-5482-3780; KAYA, ZEYNEP/0000-0002-8468-2103; KARABAY, OGUZ/0000-0003-1514-1685; Karabay, Oguz/0000-0003-0502-432X; Kaya, Sehnaz/0000-0003-0002-1517 WOS: 000347654600011 PubMed: 25564124 Background: Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. Methods: Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs. Surgical procedures (SPs) were classified into 22 types according to International Classification of Diseases, Ninth Revision criteria. Results: We recorded 1879 SSIs, associated with 41,563 SPs (4.3%; 95% confidence interval, 4.3-4.7). Among the results, the SSI rate per type of SP compared with rates reported by the INICC and CDC NHSN were 11.9% for ventricular shunt (vs 12.9% vs 5.6%); 5.3% for craniotomy (vs 4.4% vs 2.6%); 4.9% for coronary bypass with chest and donor incision (vs 4.5 vs 2.9); 3.5% for hip prosthesis (vs 2.6% vs 1.3%), and 3.0% for cesarean section (vs 0.7% vs 1.8%). Conclusions: In most of the 22 types of SP analyzed, our SSI rates were higher than the CDC NHSN rates and similar to the INICC rates. This study advances the knowledge of SSI epidemiology in Turkey, allowing the implementation of targeted interventions. Copyright (C) 2015 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Published
2015

18. The course of spinal tuberculosis (Pott disease): results of the multinational, multicentre Backbone-2 study

Author

A. Batirel, H. Erdem, G. Sengoz, F. Pehlivanoglu, E. Ramosaco, S. Gülsün, R. Tekin, B. Mete, İ.İ. Balkan, D.Y. Sevgi, E. Giannitsioti, A. Fragou, S. Kaya, B. Cetin, T. Oktenoglu, A.D. Celik, B. Karaca, E.S. Horasan, M. Ulug, S. Senbayrak, E. Arslanalp, R. Hasbun, S. Ates-Guler, A. Willke, S. Senol, D. Inan, E. Güclü, G.T. Ertem, M.M. Koc, M. Tasbakan, G. Ocal, S. Kocagoz, H. Kusoglu, T. Güven, A.I. Baran, B. Dede, F.Y. Karadag, H. Yilmaz, G. Aslan, D.A. Al-Gallad, S. Cesur, R. El-Sokkary, F. Sirmatel, U. Savasci, G. Karaahmetoglu, H. Vahaboglu, OMÜ, Ege Üniversitesi, MERİÇ KOÇ, MELİHA, Acibadem University Dspace, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, and Sırmatel, Fatma

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, Adolescent, Endemic Diseases, International Cooperation, Antitubercular Agents, Kyphosis, Gibbus deformity, Scoliosis, Pott disease, Young Adult, Vertebral osteomyelitis, Humans, Medicine, Spondylitis, Aged, Retrospective Studies, Aged, 80 and over, Mediterranean Region, business.industry, Osteomyelitis, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, Spondylodiscitis, vertebral osteomyelitis, spondylitis, General Medicine, Middle Aged, medicine.disease, spinal tuberculosis, Survival Analysis, Surgery, ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS, Treatment Outcome, Infectious Diseases, ComputingMethodologies_PATTERNRECOGNITION, Surgical Procedures, Operative, Spinal tuberculosis, Female, Tuberculosis, Spinal, spondylodiscitis, InformationSystems_MISCELLANEOUS, business, Paraplegia
Abstract

PubMed ID: 26232534, We aimed to describe clinical, laboratory, diagnostic and therapeutic features of spinal tuberculosis (ST), also known as Pott disease. A total of 314 patients with ST from 35 centres in Turkey, Egypt, Albania and Greece were included. Median duration from initial symptoms to the time of diagnosis was 78 days. The most common complications presented before diagnosis were abscesses (69%), neurologic deficits (40%), spinal instability (21%) and spinal deformity (16%). Lumbar (56%), thoracic (49%) and thoracolumbar (13%) vertebrae were the most commonly involved sites of infection. Although 51% of the patients had multiple levels of vertebral involvement, 8% had noncontiguous involvement of multiple vertebral bodies. The causative agent was identified in 41% of cases. Histopathologic examination was performed in 200 patients (64%), and 74% were consistent with tuberculosis. Medical treatment alone was implemented in 103 patients (33%), while 211 patients (67%) underwent diagnostic and/or therapeutic surgical intervention. Ten percent of the patients required more than one surgical intervention. Mortality occurred in 7 patients (2%), and 77 (25%) developed sequelae. The distribution of the posttreatment sequelae were as follows: 11% kyphosis, 6% Gibbus deformity, 5% scoliosis, 5% paraparesis, 5% paraplegia and 4% loss of sensation. Older age, presence of neurologic deficit and spinal deformity were predictors of unfavourable outcome. ST results in significant morbidity as a result of its insidious course and delayed diagnosis because of diagnostic and therapeutic challenges. ST should be considered in the differential diagnosis of patients with vertebral osteomyelitis, especially in tuberculosis-endemic regions. Early establishment of definitive aetiologic diagnosis and appropriate treatment are of paramount importance to prevent development of sequelae. © 2015 European Society of Clinical Microbiology and Infectious Diseases.

Published
2015

19. International Nosocomial Infection Control Consortium (INICC) national report on device-associated infection rates in 19 cities of Turkey, data summary for 2003-2012

Author

Leblebicioglu, Hakan, Erben, Nurettin, Rosenthal, Victor Daniel, Atasay, Begum, Erbay, Ayse, Unal, Serhat, Senol, Gunes, Willke, Ayse, Ozgultekin, Asu, Altin, Nilgun, Bakir, Mehmet, Oncul, Oral, Ersoz, Gulden, Ozdemir, Davut, Yalcin, Ata Nevzat, Ozdemir, Halil, Yildizdas, Dincer, Koksal, Iftihar, Aygun, Canan, Sirmatel, Fatma, Sener, Alper, Tuna, Nazan, Akan, OTzay Arikan, Turgut, Huseyin, Demiroz, A. Pekcan, Kendirli, Tanil, Alp, Emine, Uzun, Cengiz, Ulusoy, Sercan, Arman, Dilek, Ozgunes, Ilhan, Usluer, Gaye, Kilic, Atila, Arsan, Saadet, Cabadak, Hatice, Sen, Suha, Gelebek, Yasemin, Zengin, Humeyra, Topeli, Arzu, Alper, Yusuf, Meric, Meliha, Azak, Emel, Inan, Asuman, Turan, Guldem, Haznedaroglu, Tuncer, Gorenek, Levent, Acar, Ali, Cesur, Salih, Engin, Aynur, Kaya, Ali, Kuyucu, Necdet, Geyik, Mehmet Faruk, Aydin, Ozlem Cetinkaya, Erdogan, Nurse Selvi, Turhan, Ozge, Gunay, Nurgul, Gumus, Eylul, Dursun, Oguz, Esen, Saban, Ulger, Fatma, Dilek, Ahmet, Yilmaz, Hava, Sunbul, Mustafa, Gokmen, Zeynel, Ozdemir, Sonay Incesoy, Horoz, Ozden Ozgur, Yylmaz, Gurdal, Kaya, Selcuk, Ulusoy, Hulya, Kucukoduk, Sukru, Ustun, Cemal, Baysal, Abant Izzet, Otkun, Metin, Tulunay, Melek, Oral, Mehmet, Unal, Necmettin, Cengiz, Mustafa, Yilmaz, Leyla, Sacar, Suzan, Sungurtekin, Hulya, Ugurcan, Dogac, Yetkin, M. Arzu, Bulut, Cemal, Erdinc, F. Sebnem, Hatipoglu, Cigdem Ataman, Ince, Erdal, Ciftci, Ergin, Odek, Caglar, Yaman, Ayhan, Karbuz, Adem, Aldemir, Bilge, Kilic, Aysegul Ulu, Arda, Bilgin, Bacakoglu, Feza, Hizel, Kenan, [Leblebicioglu, Hakan -- Esen, Saban -- Ulger, Fatma -- Dilek, Ahmet -- Yilmaz, Hava -- Sunbul, Mustafa] Ondokuz Mayis Univ, Sch Med, Samsun, Turkey -- [Erben, Nurettin -- Ozgunes, Ilhan -- Usluer, Gaye] Eskisehir Osmangazi Univ, Eskisehir, Turkey -- [Rosenthal, Victor Daniel] Int Nosocomial Infect Control Consortium, Ave 4580,Floor 12,Apt D, RA-1195 Buenos Aires, DF, Argentina -- [Atasay, Begum -- Kilic, Atila -- Arsan, Saadet] Ankara Univ, Sch Med, Fac Paediat, Dept Newborn Med, TR-06100 Ankara, Turkey -- [Erbay, Ayse -- Cabadak, Hatice -- Sen, Suha] Turkiye Yuksek Ihtisas Educ & Res Hosp, Ankara, Turkey -- [Unal, Serhat -- Gelebek, Yasemin -- Zengin, Humeyra -- Topeli, Arzu -- Alper, Yusuf] Hacettepe Univ, Sch Med, Ankara, Turkey -- [Senol, Gunes] Suat Seren Chest Dis & Chest Surg Training Hosp, Izmir, Turkey -- [Willke, Ayse -- Meric, Meliha -- Azak, Emel] Kocaeli Univ, Fac Med, Kocaeli, Turkey -- [Ozgultekin, Asu -- Inan, Asuman -- Turan, Guldem] Haydarpasa Numune Training & Res Hosp, Istanbul, Turkey -- [Altin, Nilgun -- Cesur, Salih] Etlik Ihtisas Training & Educ Hosp, Ankara, Turkey -- [Bakir, Mehmet -- Engin, Aynur] Cumhuriyet Univ, Sch Med, Sivas, Turkey -- [Oncul, Oral -- Haznedaroglu, Tuncer -- Gorenek, Levent -- Acar, Ali] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Istanbul, Turkey -- [Ersoz, Gulden -- Kaya, Ali -- Kuyucu, Necdet] Mersin Univ, Fac Med, Mersin, Turkey -- [Ozdemir, Davut -- Geyik, Mehmet Faruk -- Aydin, Ozlem Cetinkaya -- Erdogan, Nurse Selvi] Duzce Univ, Med Sch Infect Dis & Clin Microbiol, Duzce, Turkey -- [Yalcin, Ata Nevzat -- Turhan, Ozge -- Gunay, Nurgul -- Gumus, Eylul -- Dursun, Oguz] Akdeniz Univ, TR-07058 Antalya, Turkey -- [Ozdemir, Halil -- Gokmen, Zeynel -- Ozdemir, Sonay Incesoy] Konya Training & Res Hosp, Konya, Turkey -- [Yildizdas, Dincer -- Horoz, Ozden Ozgur] Cukurova Univ, Balcali Hosp, Adana, Turkey -- [Koksal, Iftihar -- Yylmaz, Gurdal -- Kaya, Selcuk -- Ulusoy, Hulya] Karadeniz Tech Univ, Sch Med, Trabzon, Turkey -- [Aygun, Canan -- Kucukoduk, Sukru] Ondokuz Mayis Univ, Sch Med, Neonatal Unit, Samsun, Turkey -- [Sirmatel, Fatma -- Ustun, Cemal -- Baysal, Abant Izzet] Univ Hosp, Infect Dis & Clin Microbiol, Bolu, Turkey -- [Sener, Alper -- Otkun, Metin] Onsekiz Mart Univ Canakkale, Canakkale, Turkey -- [Tuna, Nazan] Sakarya Univ, Fac Med, Sakarya, Turkey -- [Akan, OTzay Arikan -- Tulunay, Melek -- Oral, Mehmet -- Unal, Necmettin] Ankara Univ, Ibni Sina Hosp, Sch Med, TR-06100 Ankara, Turkey -- [Turgut, Huseyin -- Sacar, Suzan -- Sungurtekin, Hulya -- Ugurcan, Dogac] Pamukkale Univ, Denizli, Turkey -- [Demiroz, A. Pekcan -- Yetkin, M. Arzu -- Bulut, Cemal -- Erdinc, F. Sebnem -- Hatipoglu, Cigdem Ataman] Ankara Numune Training & Res Hosp, Ankara, Turkey -- [Kendirli, Tanil -- Ince, Erdal -- Ciftci, Ergin -- Odek, Caglar -- Yaman, Ayhan -- Karbuz, Adem -- Aldemir, Bilge] Ankara Univ, Sch Med, Dept Paediat Crit Care Med, TR-06100 Ankara, Turkey -- [Alp, Emine -- Kilic, Aysegul Ulu] Erciyes Univ, Fac Med, Kayseri, Turkey -- [Uzun, Cengiz] German Hosp, Istanbul, Turkey -- [Ulusoy, Sercan -- Arda, Bilgin -- Bacakoglu, Feza] Ege Univ, Fac Med, Izmir, Turkey -- [Arman, Dilek -- Hizel, Kenan] Gazi Univ, Sch Med, Ankara, Turkey -- [Cengiz, Mustafa -- Yilmaz, Leyla] Harran Univ, Fac Med, Sanliurfa, Turkey, Ciftci, Ergin -- 0000-0002-4955-160X, Leblebicioglu, Hakan -- 0000-0002-6033-8543, Horoz, Ozden Ozgur -- 0000-0001-7590-650X, Erben, Nurettin -- 0000-0003-0373-0132, Yalcin, Ata Nevzat -- 0000-0002-7243-7354, UNAL, SERHAT -- 0000-0003-1184-4711, MERİÇ KOÇ, MELİHA, Çukurova Üniversitesi, OMÜ, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Sırmatel, Fatma, and Ege Üniversitesi

Subjects
Male, Pediatrics, healthcare associated infection, Turkey, Antibiotic resistance, medicine.medical_treatment, health care facilities, manpower, and services, central venous catheter, Network, intensive care unit, preschool child, Turkey (republic), law.invention, Cohort Studies, Nosocomial infection, law, newborn, device infection, Prevalence, Infection control, Prospective Studies, Prospective cohort study, Child, intensive care, catheter infection, Cross Infection, Urinary tract infection, adult, Ventilator-associated pneumonia, Pneumonia, Ventilator-Associated, General Medicine, cohort analysis, INICC, Intensive care unit, infection control, Device-associated infection, Infectious Diseases, female, Equipment and Supplies, Child, Preschool, disease surveillance, Central venous catheter, devices, Cohort study, prospective study, Microbiology (medical), medicine.medical_specialty, Adolescent, Catheter-associated urinary tract infection, infection rate, Bloodstream infection, Article, critically ill patient, length of stay, Intensive care, medicine, Humans, Hospital infection, human, Healthcare-associated infection, urinary catheter, business.industry, Research, Infant, Newborn, Infant, International Nosocomial Infection Consortium, mechanical ventilator, medicine.disease, Nosocomial infection control, major clinical study, mortality, Catheter-Related Infections, Emergency medicine, ventilator associated pneumonia, Central line-associated bloodstream infections, business
Abstract

WOS: 000346433300001, PubMed ID: 25403704, Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. Methods: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods. Results: We collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U. S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI). Conclusions: DA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report., Foundation to Fight against Nosocomial Infections, The funding for the activities carried out at INICC head quarters were provided by the corresponding author, Victor D. Rosenthal, and Foundation to Fight against Nosocomial Infections.

Published
2014

20. Epidemiology and risk factors of intensive care unit-acquired infections: a prospective multicentre cohort study in a middle-income country

Author

Meric, MELİHA, Baykara, Nur, Aksoy, Suleyman, Kol, Iclal Ozdemir, YILMAZ, GÜRDAL, BEYAZIT, Nurhayat, Mete, Birgul, Vahaboglu, Haluk, [Meric, Meliha -- Aksoy, Suleyman -- Vahaboglu, Haluk] Kocaeli Univ, Dept Infect Dis & Clin Microbiol, TR-41380 Kocaeli, Turkey -- [Baykara, Nur] Kocaeli Univ, Dept Anesthesiol & Intens Care, TR-41380 Kocaeli, Turkey -- [Kol, Iclal Ozdemir] Cumhuriyet Univ, Dept Anaesthesiol & Intens Care, Sivas, Turkey -- [Yilmaz, Gurdal] Karadeniz Tech Univ, Dept Infect Dis, Trabzon, Turkey -- [Beyazit, Nurhayat] Ankara Egitim & Arastirma Hastanesi, Dept Infect Dis, Ankara, Turkey -- [Mete, Birgul] Istanbul Univ, Cerrahpasa Med Fac, Dept Infect Dis, Istanbul, Turkey, VAHABOGLU, Haluk -- 0000-0001-8217-1767, and MERİÇ KOÇ, MELİHA

Subjects
a prospective multicentre cohort study in a middle-income country-, SINGAPORE MEDICAL JOURNAL, cilt.53, ss.260-263, 2012 [Meric M., Baykara N., Aksoy S., Kol I. O. , YILMAZ G., BEYAZIT N., Mete B., Vahaboglu H., -Epidemiology and risk factors of intensive care unit-acquired infections], intensive care units, cephalosporins, nosocomial infections, risk factors, multicentre study
Abstract

WOS: 000305001300017, PubMed ID: 22511049, Introduction This study aimed to determine the incidence and risk factors of infections among patients admitted to intensive care units (ICUs) in tertiary care hospitals in Turkey. Methods Adult patients who were admitted to the ICUs of five tertiary care hospitals for over 48 hours between June and December 2007 were monitored daily. Potential risk factors such as age, gender, comorbidities, diagnosis at admission, severity of disease (Acute Physiology and Chronic Health Evaluation II scores), exposure to antibiotics, history of invasive procedures and significant medical interventions were evaluated. A multivariate analysis of these risk factors was carried out using Cox regression. Results A total of 313 patients with a median ICU stay of 12 days were selected for the study. 236 infectious episodes (33.8/1,000 ICU-days) were diagnosed among 134 patients (42.8/100 patients) in this group. Multivariate analysis revealed that exposure to a cephalosporin antibiotic (hazard ratio [95% confidence interval] 1.55 [1.10-2.19]) was an independent risk factor, whereas having a tracheostomy cannula (0.53 [0.36-0.81]) or nasogastric tube (0.48 [0.33-0.70]) was protective. Patients admitted to the ICUs from surgical wards were significantly more exposed to cephalosporins. Conclusion ICU-associated infections, which are quite high in Turkey, are largely due to inadequate infrastructure and facilities and understaffing. Abuse of antibiotics, particularly in patients who have undergone surgery, and prolonged ICU stays are significant risk factors for such infections.

Published
2012

21. Results of Nucleos(t)ide Analog Treatment Discontinuation in Hepatitis B e-Antigen-Negative Chronic Hepatitis B: NUCSTOP Study.

Author

Kiremitçi S, Koçhan K, Seven G, Biberci Keskin E, Okay G, Akkoyunlu Y, Meriç Koç M, Sümbül B, and Şentürk H

Subjects
Female, Humans, Middle Aged, Aged, Male, Hepatitis B Surface Antigens, Lamivudine therapeutic use, Antiviral Agents therapeutic use, Hepatitis B e Antigens therapeutic use, Hepatitis B virus genetics, DNA, Viral, Recurrence, Treatment Outcome, Hepatitis B, Chronic drug therapy, Hepatitis B drug therapy
Abstract

Background/aims: This study aims to investigate the effects of nucleos(t)ide analogs (NAs) discontinuation in eligible patients in accordance with the Asian Pacific Association for the Study of the Liver hepatitis B guideline and the factors affecting clinical and virological relapses., Materials and Methods: In this prospectively designed study, hepatitis B e antigen (HBeAg)-negative chronic hepatitis B patients who were followed up between 2012 and 2019 were evaluated and 57 patients were included. All participants enrolled the study were HBeAgnegative status at NA initiation., Results: The median age of the patients was 49 (29-72) years and 24 (42%) were females. The median treatment duration was 96 (36- 276) months and patients were followed for a median duration of 27 months. Sixteen patients had a previous history of NA switch, and thirteen of these patients had a history of lamivudine resistance. Thirty-eight of 57 patients (66%) developed an elevated hepatitis B virus deoxyribonucleic acid level of >2000 IU/mL at least once, defined as virological relapse and 23 (60%) of them, experienced clinical relapse. Thirty-one of 57 patients were re-treated during the follow-up, and hepatitis B surface antigen (HBsAg) loss occurred among 4 (7%) patients. All patients who experienced HBsAg loss had a history of lamivudine resistance (P = .002)., Conclusion: Despite receiving NAs suppression therapy for a long time, HBsAg loss occurs rarely. Although it was not life-threatening, most patients experienced relapses and treatment should be restarted. In our study, whether it is a coincidence that all patients with HBsAg loss are patients in whom NAs are used sequentially due to lamivudine resistance is an issue that needs to be further investigated.

Published
2024
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22. Factors Influencing HIV Infection in Children Born to HIV-Infected Mothers in Turkey

Author

Zerdali E, Mete B, Altuntaş Aydın Ö, Gündüz A, Yılmaz Nakir İ, Bolukçu S, Kumbasar Karaosmanoğlu H, Sevgi DY, Meriç Koç M, and Tabak F

Subjects
Female, Pregnancy, Humans, Adolescent, Young Adult, Adult, Middle Aged, HIV, Mothers, Turkey epidemiology, Retrospective Studies, Infectious Disease Transmission, Vertical, Anti-Retroviral Agents therapeutic use, HIV Infections complications, HIV Infections drug therapy, Pregnancy Complications, Infectious drug therapy
Abstract

Background: Human immunodeficiency virus (HIV) is still a challenge for children. About 15 to 45% of the HIV positive pregnant women can transmit the virus to their children during pregnancy, delivery and/or breastfeeding. The risk of transmission can be decreased my several measures., Aims: To identify factors associated with HIV infection in children born to HIV-infected mothers., Study Design: A multi-center retrospective cohort study., Methods: A ten-year retrospective cohort study in five dedicated HIV centers was conducted. The 325 women in our cohort were between the ages of 18 and 45. During the study period, 44 (13.5%) of these women gave birth and 51 babies were born. Of the 51 infants, 7 (13.7%) were HIV/AIDS positive., Results: Among the factors studied, breastfeeding, having a HIV-positive sibling and being on antiretroviral treatment during pregnancy and detectable HIV-RNA during delivery were found statistically significant. A multivariable logistic regression analysis showed that being on antiretroviral treatment during pregnancy is the most important predictor of mother-to-child transmission., Conclusion: Mother-to-child transmission appears to be an important route of HIV transmission in Turkey. Lack of antiretroviral treatment during pregnancy appears to be a key factor in transmission.

Published
2023
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23. Diagnosis, treatment and prevention of infective endocarditis: Turkish consensus report-2019.

Author

Şimşek-Yavuz S, Akar AR, Aydoğdu S, Berzeg Deniz D, Demir H, Hazırolan T, Ozatik MA, Özer N, Sargın M, Topçuoğlu N, Turhan N, Yılmaz MB, Azap Ö, Başaran S, Çağ Y, Çağatay AA, Çınar Aydın G, Doğan Kaya S, Hızmalı L, Işık ME, Kılıçaslan N, Menekşe Ş, Meriç-Koç M, Öztürk S, Şensoy A, Tezer-Tekçe Y, Tükenmez-Tigen E, Uygun-Kızmaz Y, Velioğlu-Öcalmaz MŞ, Yeşilkaya A, Yılmaz E, Yılmaz N, and Yılmaz-Karadağ F

Subjects
Cardiology, Consensus, Endocarditis drug therapy, Endocarditis prevention & control, Humans, Societies, Medical, Turkey, Endocarditis diagnosis
Published
2020
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24. Consensus Report on Diagnosis, Treatment and Prevention of Infective Endocarditis by Turkish Society of Cardiovascular Surgery (TSCVS), Turkish Society of Clinical Microbiology and Infectious Diseases (KLIMIK), Turkish Society of Cardiology (TSC), Turkish Society of Nuclear Medicine (TSNM), Turkish Society of Radiology (TSR), Turkish Dental Association (TDA) and Federation of Turkish Pathology Societies (TURKPATH) Cardiovascular System Study Group.

Author

Şimşek-Yavuz S, Akar AR, Aydoğdu S, Berzeg-Deniz D, Demir H, Hazırolan T, Özatik MA, Özer N, Sargın M, Topcuoğlu EN, Turhan N, Yılmaz MB, Azap Ö, Başaran S, Çağ Y, Çağatay A, Çınar G, Doğan-Kaya S, Hızmalı L, Işık ME, Kılıçaslan N, Menekşe Ş, Meriç-Koç M, Öztürk S, Şensoy A, Tezer-Tekçe Y, Tükenmez-Tigen E, Uygun-Kızmaz Y, Velioğlu-Öcalmaz MŞ, Yeşilkaya A, Yılmaz E, Yılmaz N, and Yılmaz-Karadağ F

Abstract

Infective endocarditis (IE) is rare, but associated with significant morbidity and mortality rates. Estimates of the incidence of IE in Turkey are compromised by the absence of population-based prospective studies. Due to the frequent presence of predisposing cardiac conditions and higher rates of nosocomial bacteremia in highrisk groups, the incidence of IE is expected to be higher in Turkey. Additionally, while IE generally affects older people in developed countries, it still affects young people in Turkey. In order to reduce the mortality and morbidity, it is critical to diagnose the IE to determine the causative agent and to start treatment rapidly. However, most of the patients cannot be diagnosed in their first visits, about half of them can be diagnosed after three months, and the disease often goes unnoticed. In patients diagnosed with IE, the rate of identification of causative organisms is significantly lower in Turkey than in developed countries. Furthermore, most of the centers do not perform some essential microbiological diagnostic tests as a routine practice. Some antimicrobials that are recommended as the first-line of treatment for IE, particularly antistaphylococcal penicillins, are not available in Turkey. These problems necessitate reviewing the epidemiological, laboratory, and clinical characteristics of IE in our country, as well as the current information about its diagnosis, treatment, and prevention together with local data. Physicians can follow patients with IE in many specialties. Diagnosis and treatment processes of IE should be standardized at every stage so that management of IE, a setting in which many physicians are involved, can always be in line with current recommendations. Study Group for Infective Endocarditis and Other Cardiovascular Infections of the Turkish Society of Clinical Microbiology and Infectious Diseases has called for collaboration of the relevant specialist organizations to establish a consensus report on the diagnosis, treatment, and prevention of IE in the light of current information and local data in Turkey., Competing Interests: Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article., (Copyright © 2020, Turkish Society of Cardiovascular Surgery.)

Published
2020
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