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1. A Study of the Surface Integrity of Titanium Alloy Ti-6Al-4V in the Abrasive Water Jet Machining Process

Author

M. Douiri, M. Boujelbene, S. Ben Salem, Emin Bayraktar, Laboratoire d'Ingénierie des Systèmes Mécaniques et des MAtériaux (LISMMA), Université Paris 8 Vincennes-Saint-Denis (UP8)-SUPMECA - Institut supérieur de mécanique de Paris, Laboratoire QUARTZ (QUARTZ ), Université Paris 8 Vincennes-Saint-Denis (UP8)-SUPMECA - Institut supérieur de mécanique de Paris-Ecole Nationale Supérieure de l'Electronique et de ses Applications (ENSEA)-Ecole Internationale des Sciences du Traitement de l'Information (EISTI), Université Paris 8 Vincennes-Saint-Denis (UP8)-SUPMECA - Institut supérieur de mécanique de Paris (SUPMECA), Université Paris 8 Vincennes-Saint-Denis (UP8)-Ecole Nationale Supérieure de l'Electronique et de ses Applications (ENSEA)-SUPMECA - Institut supérieur de mécanique de Paris (SUPMECA)-Ecole Internationale des Sciences du Traitement de l'Information (EISTI), and Université Paris 8 Vincennes-Saint-Denis (UP8)-SUPMECA - Institut supérieur de mécanique de Paris (SUPMECA)-Ecole Nationale Supérieure de l'Electronique et de ses Applications (ENSEA)-Ecole Internationale des Sciences du Traitement de l'Information (EISTI)

Subjects
0209 industrial biotechnology, Materials science, Abrasive, Nozzle, Titanium alloy, 02 engineering and technology, Abrasive water jet, [CHIM.MATE]Chemical Sciences/Material chemistry, Microstructure, [SPI.MAT]Engineering Sciences [physics]/Materials, [PHYS.MECA.MEMA]Physics [physics]/Mechanics [physics]/Mechanics of materials [physics.class-ph], 020303 mechanical engineering & transports, 020901 industrial engineering & automation, 0203 mechanical engineering, Surface roughness, Ti 6al 4v, Composite material, ComputingMilieux_MISCELLANEOUS, Surface integrity
Abstract

The abrasive water jet (AWJ) cutting technique is one the most rapidly improving technological methods of cutting materials. In this cutting technique, a thin, high velocity water jet accelerates abrasive particles that are directed through an abrasive water jet nozzle at the material to be cut.

Published
2018

2. Comparison of NovoPen 3 and syringes/vials in the acceptance of insulin therapy in NIDDM patients with secondary failure to oral hypoglycaemic agents.

Author

Kadiri A, Chraibi A, Marouan F, Ababou MR, el Guermai N, Wadjinny A, Kerfati A, Douiri M, Bensouda JD, Belkhadir J, and Arvanitis Y

Subjects
Administration, Oral, Blood Glucose analysis, Cross-Over Studies, Humans, Injections, Subcutaneous, Insulin therapeutic use, Diabetes Mellitus, Type 2 drug therapy, Hypoglycemic Agents therapeutic use, Insulin administration & dosage, Syringes
Abstract

This open, randomised, cross-over study compared the acceptance and safety of NovoPen 3 with that of conventional syringes and vials when initiating insulin treatment in 96 NIDDM patients with secondary failure to oral hypoglycaemic agents. These patients had not previously been treated with insulin. All patients used each insulin administration system for 12 weeks. Group A started therapy using NovoPen 3 and crossed over to syringe/vial administration; Group B started with syringe/vial administration followed by NovoPen 3. In total, 78 patients completed the study. Most patients in Group A initially found the insulin injections very easy or easy and many of those who found injections easy at first found them very easy by the end of week 12. During the first period, patients in Group B found insulin administration more difficult than those in Group A. Injection pain was significantly lower with NovoPen 3 than with syringes and vials (P = 0.0018). Patients in Group B reported a significantly lower level of injection pain after the switch to using NovoPen 3 (P = 0.0003). Acceptance of insulin injections was significantly higher by patients using NovoPen 3 than by those using syringes and vials (P = 0.0059). Setting and drawing up the dose of insulin was also easier for patients using NovoPen 3 (P = 0.0490). At the end of the study, most patients (89.5% (68/76 replies)) said that they preferred NovoPen 3 to syringes and vials. Glycaemic control improved compared with baseline after starting insulin therapy, with no differences between Groups A and B, or between the two injection systems. The number of reported hypoglycaemic episodes was very low and was not significantly different between Groups A and B, or between the two administration systems. No treatment-related adverse events were reported. We conclude that use of NovoPen 3 provides better acceptance of insulin injection than use of conventional syringes and vials during initiation of insulin therapy in NIDDM patients with secondary failure to treatment with oral hypoglycaemic agents.

Published
1998
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