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A Selectfluor-initiated cyanation of disulfides to thiocyanates has been developed. In this process, Selectfluor was employed as the oxidant and trimethylsilyl cyanide was used as the cyanation reagent. It provides an eco-friendly and simple way to synthesize the thiocyanates. [ABSTRACT FROM AUTHOR]

Purpose This paper aims to study the anodization of aluminum in a mixture solution of 1,3-propanediol solutions and 0.4 mol l−1 H3PO4 at a low temperature.Design/methodology/approach The morphology and composition of the resulting anodic aluminum oxide (AAO) template was characterized by means of a scanning electron microscope in combination with an energy dispersive spectrometer.Findings Pore density and pore diameter both were found to be dependent on the temperature of anodization.Originality/value The resulting AAO templates exhibited uniform and regular pores with diameters that were significantly smaller than those found in AAO templates anodized at room temperature. [ABSTRACT FROM AUTHOR]

Purpose This paper aims to study the anodization of aluminum in a mixture solution of 1,3-propanediol solutions and 0.4 mol l−1 H3PO4 at a low temperature.Design/methodology/approach The morphology and composition of the resulting anodic aluminum oxide (AAO) template was characterized by means of a scanning electron microscope in combination with an energy dispersive spectrometer.Findings Pore density and pore diameter both were found to be dependent on the temperature of anodization.Originality/value The resulting AAO templates exhibited uniform and regular pores with diameters that were significantly smaller than those found in AAO templates anodized at room temperature. [ABSTRACT FROM AUTHOR]

[Display omitted] Nickel-catalyzed reduction of (het)arenecarboxylic acids with hydrosilanes in the presence of dimethyl dicarbonate as the activator affords the corresponding aldehydes. The role of the activator is the conversion of the acids into their anhydrides undergoing C–O cleavage. The good yields were achieved in case of substrates bearing electron-donating and electron-neutral groups. [ABSTRACT FROM AUTHOR]

The thermo-sensitive copolymer poly( N -vinylcaprolactam- co -methacrylic acid) (PNVCL- co -MAA) was synthesized by free radical polymerization and the resulting nanofibers were fabricated using an electrospinning process. The molecular weight of the copolymer was adjusted by varying the content of methacrylic acid (MAA) while keeping that of N -vinylcaprolactam (NVCL) constant. Hydrophilic captopril and hydrophobic ketoprofen were used as model drugs, and PNVCL- co -MAA nanofibers were used as the drug carrier to investigate the effects of drug on its release properties from nanofibers at different temperatures. The results showed that slow release over several hours was observed at 40 °C (above the lower critical solution temperature (LCST) of PNVCL- co -MAA), while the drugs exhibited a burst release of several seconds at 20 °C (below the LCST). Drug release slowed with increasing content of the hydrophobic monomer NVCL. The hydrophilic captopril was released at a higher rate than the hydrophobic ketoprofen. The drug release characteristics were dependent on the temperature, the portion of hydrophilic groups and hydrophobic groups in the copolymer and hydrophilicity/hydrophobicity of drug. Study on the mechanism of release showed that Korsmeyer–Peppas model as a major drug release mechanism. Given these results, the PNVCL- co -MAA copolymers are proposed to have useful applications in intellectual drug delivery systems. [ABSTRACT FROM AUTHOR]

Dipeptides and their derivatives have attracted tremendous attention owning to their excellent abilities of self-assemble assembling into various structures which have great potentials for applications in biology and/or nanotechnology. In the present study, we dedicate to fabricate a rigid and structure controllable Fmoc-FF/SA composite hydrogel. We found that the modified dipeptide, fluorenyl-9-methoxycarbonyl (Fmoc)-diphenylalanine (Phe-Phe) can self-assemble into rigid hydrogels with structures of nanowires, layered thin films or honeycombs as the change of sodium alginate (SA) concentration. Meanwhile, CD-spectroscopy demonstrated that SA appeared to control the process, but it did not change the arrangement of the Fmoc-FF peptide. Our results demonstrated that the formed hydrogel showed physical and chemical stability as well as possessing good biocompatibility. Rheological measurements showed that the addition of SA could improve the stability of the hydrogel. Cell viability assay revealed that the Fmoc-FF and Fmoc-FF/SA hydrogels are both beneficial for cell proliferation in-vitro . Our results indicated that the fabricated Fmoc-FF/SA composite hydrogels could be used in tissue engineering and drug delivery in the future. [ABSTRACT FROM AUTHOR]