239 results on '"Ladds, Graham"'
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2. Binding kinetics drive G protein subtype selectivity at the β1-adrenergic receptor
3. GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion
4. Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow
5. Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression
6. ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism.
7. Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor.
8. Intracellular pathways of calcitonin gene‐related peptide‐induced relaxation of human coronary arteries: A key role for Gβγ subunit instead of cAMP.
9. RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis
10. Novel mathematical and computational models of G protein–coupled receptor signalling
11. Proposed model of the Dictyostelium cAMP receptors bound to cAMP
12. Combinatorial expression of GPCR isoforms affects signalling and drug responses
13. Structure‐based identification of dual ligands at the A2AR and PDE10A with anti‐proliferative effects in lung cancer cell‐lines
14. Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets
15. CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells
16. Exploring bias in platelet P2Y1 signalling: Host defence versus haemostasis.
17. Binding kinetics drive G protein subtype selectivity at the β1-adrenergic receptor.
18. Pharmacological characterisation of novel adenosine A3 receptor antagonists
19. Adaptation with the fission yeast Schizosaccharomyces pombe : the characterisation of the secreted serine carboxypeptidase Sxa2
20. Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses
21. BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
22. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
23. Parameter identification problems in the modelling of cell motility
24. Discovery and Structure–Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists.
25. Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons
26. Ras activation revisited: role of GEF and GAP systems
27. Regulators of G protein signalling proteins in the human myometrium
28. Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure−Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.
29. Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow.
30. Interactions Between RAMP2 And CRF Receptors:The Effect Of Receptor Subtypes, Splice Variants And Cell Context
31. Discovery of a High Affinity Adenosine A1/A3 Receptor Antagonist with a Novel 7‑Amino-pyrazolo[3,4‑d]pyridazine Scaffold.
32. Non-opioid analgesia based on Gα signalling bias
33. A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression
34. An efficient bipartite PCR technique to introduce specific changes in large plasmids
35. Identifying regulators of pheromone signalling in the fission yeast Schizosaccharomyces pombe
36. Determining the Effects of Differential Expression of GRKs and β-arrestins on CLR-RAMP Agonist Bias.
37. Functional analysis of heterologous GPCR signalling pathways in yeast
38. The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor Activation.
39. Promiscuous receptor activation mediates glucagonostatic effects of GLP-1(9-36) and GLP-1(7-36)
40. The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae
41. A constitutively active GPCR retains its G protein specificity and the ability to form dimers
42. Emerging roles of adhesion G protein-coupled receptors.
43. Paracrine Oxytocin and Estradiol Demonstrate a Spatial Increase in Human Intrauterine Tissues with Labor
44. Modified yeast cells to investigate the coupling of G protein-coupled receptors to specific G proteins
45. Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe
46. A temperature-sensitive Krp1 allows in vivo characterization of kexin activation
47. Sxa2 is a serine carboxypeptidase that degrades extracellular P-factor in the fission yeast Schizosaccharomyces pombe
48. Multisite Model of Allosterism for the Adenosine A1 Receptor.
49. Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor.
50. SXA2, A CARBOXYPEPTIDASE THAT DEGRADES EXTRACELLULAR PHEROMONE IN THE FISSION YEAST SCHIZOSACCHAROMYCES POMBE: N149
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