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Background Objectives Methods Results Conclusion Neomycin is an aminoglycoside antibiotic that may cause contact allergy. It was withdrawn as a medicine for human use in Denmark in October 2009 but is still found in some vaccines.To identify time trends in contact allergy to neomycin in the period from 2000 to 2023.A cross‐section study of patients ≥18 years consecutively patch‐tested with neomycin sulfate (20% in pet.) at Gentofte Hospital, Denmark, during the period 2000–2023 was conducted.The overall prevalence of contact allergy to neomycin was 1.4%. The prevalence was significantly lower in the period ‘2010–2023’ (1.2%) than in ‘2000–2009’ (1.8%) (p < 0.005). Contact allergy to neomycin was significantly positively associated with facial dermatitis and age >40 years, and significantly negatively associated with occupational dermatitis and hand dermatitis. No changes in sex, occupational dermatitis, atopic dermatitis, hand dermatitis, leg dermatitis, facial dermatitis, or age > 40/≤40 (the MOAHLFA‐index) were identified when comparing neomycin contact allergic‐patients in the two periods ‘2010–2023’ and ‘2001–2009’.Neomycin is a rare cause of contact allergy in Denmark with a significantly lower prevalence following its withdrawal as a medicinal product for human use in Denmark in 2009. [ABSTRACT FROM AUTHOR]

This article presents the findings of an observational study conducted in Denmark on contact allergy to textile dye mix (TDM) in eczema patients. The study analyzed historical data from 2015 to 2023 and found that the overall prevalence of contact allergy to TDM was 2.3%. There was no significant trend in the prevalence of contact allergy to TDM over the study period. The study also identified associations between contact allergy to TDM and factors such as leg eczema. The authors suggest that further research is needed to better understand long-term trends in contact allergy to textile dyes. [Extracted from the article]

Background: Rubber accelerators are used in the production of rubber gloves and may cause contact allergy. Objectives: To estimate long‐term trend and prevalence of contact allergy to rubber accelerators for a 30‐year period in Denmark, high‐risk occupations, and exposures. Methods: Data from all patients with contact dermatitis consecutively patch tested at the department of Skin and Allergy Gentofte hospital with the rubber accelerators from the European baseline series (EBS) from 1990 to 2019, were analysed. Further, patients under suspicion of rubber accelerator contact allergy were additionally patch‐tested with rubber accelerators from the specialised rubber series from 2005 to 2019 and these were additional extracted. Results: The overall prevalence of contact allergy to one or more of the rubber accelerators from the EBS series was 2.7% with a significant decline in the first 12‐years, followed by a stable frequency in the past 18‐years. Associations with occupational contact dermatitis, hand dermatitis, and leg/foot dermatitis were found. Wet‐work occupations were most often affected and gloves the most frequent exposure. Conclusions: Contact allergy to one or more of the rubber accelerators from the EBS is frequent and has been unchanged for several decades, which calls for prevention. [ABSTRACT FROM AUTHOR]

This document is a summary of two scientific articles related to contact allergies. The first article focuses on the prevalence of contact allergy to N-isopropyl-N0-phenyl paraphenylenediamine (IPPD) in eczema patients in Denmark. The study found a low prevalence of IPPD contact allergy, with no significant associations between the allergy and various variables. The second article discusses the prevalence of occupational contact allergies in Europe based on patch test data collected from 2011 to 2020. The study provides insights into the types and frequency of allergens causing contact allergies. Both articles provide valuable information for researchers studying contact allergies. [Extracted from the article]

An abscess is a collection of pus forming a cavity in the tissue, for example, the skin. They are generally perceived as the result of infection but infection is not mandatory for the diagnosis. Skin abscesses may occur independently (primary) or be part of other diseases such as the recurrent inflammatory skin disease hidradenitis suppurativa (HS). HS is noninfectious but nevertheless abscesses are a common differential diagnosis. The purpose of this study is to review the microbiome of bacteria positive primary skin abscesses in order to explore the reported microbiota. EMBASE, MEDLINER, and COCHRANE LIBRABRY were searched on 9th of October 2021 for microbiome, skin, and abscesses. Studies with more than 10 patients reporting the microbiome in human skin‐abscesses were included and studies with abscess microbiota sampled from HS patients, microbiota not sampled from skin‐abscesses, missing information on microbiome data, sampling bias, studies in other language than English or Danish, reviews and meta‐analyses were excluded. In total 11 studies were included for further analysis. S. aureus is likely to dominate the microbiome of bacteria positive primary skin abscesses in contrast to the polymicrobial microbiome of HS. [ABSTRACT FROM AUTHOR]

Regular and correct glove use is important[3] and it may impair compliance when almost one-third of the hairdressers report gloves as reasons for their hand eczema, as hairdressers may begin to question the overall benefit of gloves. Of these, 93.8% (544/580) had worked in the hairdressing occupation at the onset of hand eczema and 84.1% (487/579) believed their hand eczema were caused or exacerbated by their occupation. Keywords: contact dermatitis; hairdressers; hand eczema; occupational disease EN contact dermatitis hairdressers hand eczema occupational disease 162 164 3 01/13/23 20230201 NES 230201 INTRODUCTION Hairdressers have a high incidence of occupational hand eczema (OHE).[1] The risk of OHE in hairdressers is associated with a high degree of occupational exposure to wet work and allergens in hair cosmetics. [Extracted from the article]

Objectives: Self-reported hand eczema was previously found under-reported as an occupational disease to the authorities among Danish hairdressers graduating from 1985 to 2007. This study investigates whether self-reported hand eczema among Danish hairdressers graduating from 2008 to 2018 is under-reported as an occupational disease to the authorities., Methods: A cross-sectional study on all Danish hairdressers graduating from 2008 to 2018 was conducted. The participants were identified using information from the Danish Hairdressers' and Beauticians' Union. In May 2020, a self-administered survey on hand eczema was sent to all hairdressers., Results: A response rate of 30.7% (1485/4830) was obtained. The lifetime prevalence of self-reported hand eczema was 40.1%, and 84.1% of hairdressers with hand eczema believed it to be occupational of whom 27.0% answered it was reported as an occupational disease to the authorities. Of hairdressers believing their hand eczema was occupational, consulting a doctor and answering it was reported as an occupational disease, 94.4% had consulted a dermatologist. The main reason for not reporting was 'I would probably not gain anything from it anyway' (40.0%)., Conclusions: Based on hairdressers' perception, occupational hand eczema still seems to be an under-reported disease which may lead to underestimation of the problem and impair prevention, diagnosis and treatment., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)