15 results on '"Katie Cook"'
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2. Autism and Me - Autism Book for Kids Ages 8-12 : An Empowering Guide with 35 Exercises, Quizzes, and Activities!
- Author
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Katie Cook MEd, BCBA and Katie Cook MEd, BCBA
- Abstract
Help children understand their autism and thrive with this positive guide for kids ages 8 to 12 We all think differently. This notion is celebrated in Autism and Me, a guide that helps children with autism spectrum disorder (ASD) gain a better understanding of how their brain works. The book highlights positive ASD traits while showing kids how they can work through some of its challenges as well. Unlike some other autism books for kids, this guide offers: Awesome activities—Interactive exercises encourage kids to apply the concepts discussed in a fun, low-stakes way, from fill-in-the-blanks and multiple choice quizzes to drawing and coloring. Proven strategies—From improving communication skills to developing self-care habits, kids will find strategies to help them better navigate school, social functions, and family life. True stories—Each chapter begins with real life anecdotes, offering relatable experiences from others on the autism spectrum and helping kids feel less alone. Kids will learn to manage emotions, make friends, and flourish with this strengths-based autism book.
- Published
- 2021
3. Thriving with Autism : 90 Activities to Encourage Your Child's Communication, Engagement, and Play
- Author
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Katie Cook MEd, BCBA and Katie Cook MEd, BCBA
- Subjects
- Play therapy, Games--Therapeutic use, Parents of developmentally disabled children--Handbooks, manuals, etc, Parents of autistic children--Handbooks, manuals, etc, Educational games, Autistic children--Rehabilitation, Children with autism spectrum disorders--Rehabilitation, Autistic children--Behavior modification, Autistic children--Means of communication
- Abstract
Help children with autism strengthen their connections—supportive strategies for ages 1 to 11 To guide your efforts to help your child flourish, this book has 90 playful, evidence-based activities. Thriving with Autism provides an easy, effective toolbox to supplement and support the developmental work parents and caregivers are doing with their children. These solutions are designed for kids with autism from ages 1 to 11. The benefits can last a lifetime. From building better conversation abilities to strengthening social skills, Thriving with Autism delivers practical, everyday ways to connect, encourage, and play. Featuring exercises like Acts of Friendliness, The Human Burrito, and Emotional Charades, this comprehensive guide encourages your child with autism to boost their communication, engagement, and self-regulation skills. Thriving with Autism includes: Hands-on activities—Make learning fun with lots of lessons that can help kids across the autism spectrum. Simple strategies—Tackle these easy, research-driven activities one by one at home. Engaging and practical—Find helpful tips and suggestions, as well as full-color illustrations that are sure to inspire and delight you and your child. Now there's a smart, sensible way to help teach kids with autism necessary skills.
- Published
- 2020
4. Jim Henson's Fraggle Rock #4
- Author
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Jim Henson, Katie Cook, Jim Henson, and Katie Cook
- Abstract
A new story from bestseller Katie Cook that uses music to explore every cave and bog of Fraggle Rock like never before.
- Published
- 2018
5. Book Reviews
- Author
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Aliraza Javaid and Katie Cook
- Subjects
lcsh:Sociology (General) ,lcsh:HM401-1281 ,book review - Abstract
Criminal Justice: An Introduction to Philosophies, Theories and Practice Reviewed by Aliraza Javaid Canadian Policing in the 21st Century: A Frontline Officer on Challenges and Changes Reviewed by Katie Cook
- Published
- 2014
6. Munchkin Vol. 5
- Author
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Steve Jackson, Katie Cook, Will Hindmarch, Steve Jackson, Katie Cook, and Will Hindmarch
- Abstract
Based on the mega-hit card game about dungeon adventure, join Spyke and Flower as they compete in fairs, battle Cthulhu monsters, visit Oz, and go on dungeon crawls all in the name of racking up that loot. Collects issues #17-20 of the Munchkin comic with stories from the world of the fantasy roleplaying satire.
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- 2017
7. Munchkin #20
- Author
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Steve Jackson, Katie Cook, Will Hindmarch, Steve Jackson, Katie Cook, and Will Hindmarch
- Abstract
Feeling glum, chum? Turn that frown upside down with some dungeon-dwelling fun! This issue ties into the Munchkin Gloom and Moop's Monster Mashup game releases.
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- 2016
8. Munchkin #19
- Author
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Steve Jackson, Katie Cook, Will Hindmarch, Steve Jackson, Katie Cook, and Will Hindmarch
- Abstract
To tie in with the release of Katie Cook's Munchkin Cthulhu Guest Artist Edition card set from Steve Jackson Games, Katie will be joining us this month as the writer of a Cthulhu-themed Munchkin tale!
- Published
- 2016
9. A Goniopora stokesi community at Tatsugasako, Otsuki, Kochi, Japan: a new northernmost specimen-based record.
- Author
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REIMER, JAMES DAVIS, TAKUMA FUJII, HIROKI KISE, KENSUKE YANAGI, KATIE COOK, CANT, JAMES, KEITA KOEDA, TATSUKI KOIDO, TAKAYA KITAMURA, and TAKUMA MEZAKI
- Subjects
CLIMATE change ,MARINE animals ,MARINE plants - Abstract
The zooxanthellate scleractinian species Goniopora stokesi is widely distributed across the Indo-Pacific Ocean, and in Japan the northernmost records of this species are from Tatsukushi, Kochi on Shikoku, although these records are not associated with specimens deposited in museums. The species is unique among Goniopora in that it lives on soft bottom sediment, forming free-living colonies, and produces asexual daughter colonies, or "polyp balls," via budding from parent colonies. Here we report on a large G. stokesi community from Otsuki, Kochi, Japan, representing the northernmost specimen-based record of the species. Specimen-based records are important as verifiable baseline data in light of global warming and climate change, which is expected to drastically effect the marine flora and fauna of Kochi and surrounding areas. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
10. Directly administered antiretroviral therapy for HIV-infected individuals in opioid treatment programs: results from a randomized clinical trial
- Author
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Cynthia S. Rand, Katie Cook, Richard D. Moore, Noya Galai, Krisann K. Oursler, Bernadette Anna Mullen, Mary E. McCaul, Sheldon Glass, and Gregory M. Lucas
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Male ,Non-Clinical Medicine ,lcsh:Medicine ,HIV Infections ,Drug resistance ,Logistic regression ,law.invention ,0302 clinical medicine ,Randomized controlled trial ,law ,Hiv infected ,030212 general & internal medicine ,lcsh:Science ,Psychiatry ,0303 health sciences ,Multidisciplinary ,Substance Abuse ,HIV diagnosis and management ,Viral Load ,Middle Aged ,Antivirals ,3. Good health ,Analgesics, Opioid ,Mental Health ,Treatment Outcome ,Medicine ,Infectious diseases ,Female ,Public Health ,Viral load ,medicine.drug ,Research Article ,Adult ,medicine.medical_specialty ,Clinical Research Design ,Anti-HIV Agents ,Retrovirology and HIV immunopathogenesis ,Viral diseases ,Microbiology ,03 medical and health sciences ,Pharmacotherapy ,Internal medicine ,Virology ,medicine ,Humans ,Clinical Trials ,Biology ,030306 microbiology ,business.industry ,lcsh:R ,HIV ,Antiretroviral therapy ,Medical Practice Management ,Opioid ,Physical therapy ,lcsh:Q ,business ,Viral Transmission and Infection - Abstract
Background Data regarding the efficacy of directly administered antiretroviral therapy (DAART) are mixed. Opioid treatment programs (OTPs) provide a convenient framework for DAART. In a randomized controlled trial, we compared DAART and self-administered therapy (SAT) among HIV-infected subjects attending five OTPs in Baltimore, MD. Methods HIV-infected individuals attending OTPs were eligible if they were not taking antiretroviral therapy (ART) or were virologically failing ART at last clinical assessment. In subjects assigned to DAART, we observed one ART dose per weekday at the OTP for up to 12 months. SAT subjects administered ART at home. The primary efficacy comparison was the between-arm difference in the average proportions with HIV RNA
- Published
- 2013
11. The Impact of Choice and Control on Women's Childbirth Experiences
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Katie Cook and Colleen Loomis
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Recall ,business.industry ,media_common.quotation_subject ,Control (management) ,Birth plan ,Obstetrics and Gynecology ,Affect (psychology) ,Pediatrics ,Article ,Developmental psychology ,Feeling ,ddc:370 ,Maternity and Midwifery ,Pediatrics, Perinatology and Child Health ,Childbirth ,Medicine ,Narrative ,Descriptive research ,business ,media_common - Abstract
Women’s choice and control impact birthing experiences. This study used a qualitative, descriptive approach to explore how women develop their initial birth plan and how changes made to the plan affect overall birth experiences. Narrative, semistructured interviews were conducted with 15 women who had given birth in Waterloo Region, Ontario, Canada, and data were analyzed using a phenomenological approach. Findings showed that women relied on many resources when planning a birth and that changes made to a woman’s initial birth plan affected her recollection of the birth experience. Conclusions are that women’s positive and negative recollections of their birth experiences are related more to feelings and exertion of choice and control than to specific details of the birth experience.
- Published
- 2012
12. Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
- Author
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Lucy I. Crouch, Marcelo V. Liberato, Paulina A. Urbanowicz, Arnaud Baslé, Christopher A. Lamb, Christopher J. Stewart, Katie Cooke, Mary Doona, Stephanie Needham, Richard R. Brady, Janet E. Berrington, Katarina Madunic, Manfred Wuhrer, Peter Chater, Jeffery P. Pearson, Robert Glowacki, Eric C. Martens, Fuming Zhang, Robert J. Linhardt, Daniel I. R. Spencer, and David N. Bolam
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Science - Abstract
Epithelial cells that line the gut secrete complex glycoproteins that form a mucus layer to protect the gut wall from enteric pathogens. Here, the authors provide a comprehensive characterisation of endo-acting glycoside hydrolases expressed by mucin-degrading members of the microbiome that are able to cleave the O-glycan chains of a range of different animal and human mucins.
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- 2020
- Full Text
- View/download PDF
13. MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis
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Nina P. Jordan, Samuel J. Tingle, Victoria G. Shuttleworth, Katie Cooke, Rachael E. Redgrave, Esha Singh, Emily K. Glover, Hafiza B. Ahmad Tajuddin, John A. Kirby, Helen M. Arthur, Chris Ward, Neil S. Sheerin, and Simi Ali
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endothelial-to-mesenchymal transition ,fibrosis ,microRNA ,miR-126 ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
In fibrotic diseases, myofibroblasts derive from a range of cell types including endothelial-to-mesenchymal transition (EndMT). Increasing evidence suggests that miRNAs are key regulators in biological processes but their profile is relatively understudied in EndMT. In human umbilical vein endothelial cells (HUVEC), EndMT was induced by treatment with TGFβ2 and IL1β. A significant decrease in endothelial markers such as VE-cadherin, CD31 and an increase in mesenchymal markers such as fibronectin were observed. In parallel, miRNA profiling showed that miR-126-3p was down-regulated in HUVECs undergoing EndMT and over-expression of miR-126-3p prevented EndMT, maintaining CD31 and repressing fibronectin expression. EndMT was investigated using lineage tracing with transgenic Cdh5-Cre-ERT2; Rosa26R-stop-YFP mice in two established models of fibrosis: cardiac ischaemic injury and kidney ureteric occlusion. In both cardiac and kidney fibrosis, lineage tracing showed a significant subpopulation of endothelial-derived cells expressed mesenchymal markers, indicating they had undergone EndMT. In addition, miR-126-3p was restricted to endothelial cells and down-regulated in murine fibrotic kidney and heart tissue. These findings were confirmed in patient kidney biopsies. MiR-126-3p expression is restricted to endothelial cells and is down-regulated during EndMT. Over-expression of miR-126-3p reduces EndMT, therefore, it could be considered for miRNA-based therapeutics in fibrotic organs.
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- 2021
- Full Text
- View/download PDF
14. Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells
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Irene del Molino del Barrio, Annette Meeson, Katie Cooke, Mohammed Imad Malki, Ben Barron-Millar, John A. Kirby, and Simi Ali
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breast cancer ,chemokines ,metastasis ,CCL21 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Chemokine receptor CCR7 is implicated in the metastasis of breast cancer to the lymph nodes. Chemokine function is dependent upon their binding to both cell-surface heparan sulphate (HS) and to their specific receptors; thus, the role of HS in CCR7-mediated lymph node metastasis was investigated by creating a non-HS binding chemokine CCL21 (mut-CCL21). Mut-CCL21 (Δ103–134) induced leukocyte chemotaxis in diffusion gradients but did not stimulate trans-endothelial migration of PBMCs (p < 0.001) and 4T1-Luc cells (p < 0.01). Furthermore, the effect of heparin and HS on the chemotactic properties of wild-type (WT) and mut-CCL21 was examined. Interestingly, heparin and HS completely inhibit the chemotaxis mediated by WT-CCL21 at 250 and 500 µg/mL, whereas minimal effect was seen with mut-CCL21. This difference could potentially be attributed to reduced HS binding, as surface plasmon resonance spectroscopy showed that mut-CCL21 did not significantly bind HS compared to WT-CCL21. A murine model was used to assess the potential of mut-CCL21 to prevent lymph node metastasis in vivo. Mice were injected with 4T1-Luc cells in the mammary fat pad and treated daily for a week with 20 µg mut-CCL21. Mice were imaged weekly with IVIS and sacrificed on day 18. Luciferase expression was significantly reduced in lymph nodes from mice that had been treated with mut-CCL21 compared to the control (p = 0.0148), suggesting the potential to target chemokine binding to HS as a therapeutic option.
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- 2021
- Full Text
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15. The Role of the Clinical Pharmacist in an Irish University Teaching Hospital: A Mixed-Methods Study
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Sarah Ronan, Nicola Shannon, Katie Cooke, Trish McKeon, Elaine K Walsh, Alan Kearney, and Laura J Sahm
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medication review ,cost avoidance ,adverse drug events ,views of nurses ,cost benefit ratio ,semi-structured interviews ,Pharmacy and materia medica ,RS1-441 - Abstract
Medication review (MR) is a vital part of the pharmacist’s role in hospital. However, in the South Infirmary Victoria University Hospital (SIVUH), Cork, Ireland, this has not been fully implemented due to resource issues. In addition, the cost of providing this service has not been evaluated. Moreover, it is not clear how other members of the multidisciplinary team e.g. Nurses, value any interventions made as a result of the MR. This mixed methods study assessed the impact of MR in terms of (i) potential clinical harm, (ii) cost avoidance and (iii) the views of nursing staff on the role of the pharmacist. The setting is a 192-bed, voluntary, acute hospital, in the Munster region of Ireland. Study I: The pharmacist provided MR to patients conventionally once a week. Any interventions were then assessed for potential clinical harm and to calculate cost avoidance. Study II: Semi-structured interviews, guided by a topic guide were completed with 12 nurses (11 female). Thematic analysis was used to code the main themes. Main outcome measure: To estimate the cost, cost avoidance, and the net cost benefit ratio of MR provided by pharmacists. Study I: Of 128 patients who received the MR, 113 interventions were made. The estimated cost of providing the MR was €2,559 (senior pharmacist). Using €1084 as the cost of an adverse drug event (ADE), the cost avoidance was calculated at €42,330. This led to a net cost benefit of €39,771 (senior pharmacist) which equated to a net cost benefit ratio of 16.5:1. Study II: The main themes were (i) perceptions of pharmacy services, (ii) the role of the pharmacist—past, present and future, and (iii) teamwork and communication. Nurses expressed a desire to have more pharmacists present on the wards.
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- 2020
- Full Text
- View/download PDF
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