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Your search keyword '"Katherine A. Hanley"' showing total 2 results
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2 results on '"Katherine A. Hanley"'

1. Association between pre-admission acid suppressive medication exposure and severity of illness in patients hospitalized with COVID-19

Author

Teldon B. Alford, Millie Chau, Kulwinder S. Dua, Gail McNulty, Abdul Haseeb, Gulsum Anderson, Joy M. Hutchinson, Gabriela N. Kuftinec, Amar R. Deshpande, Vaishali Patel, Soumil Patwardhan, Melanie Mays, Sunil Amin, B. Joseph Elmunzer, Amy Hosmer, Andrew M. Aneese, Rosemary Nustas, Weijing Tang, Natalia H. Zbib, Liam Hilson, Benita K. Glamour, Molly Orosey, Amitabh Chak, Christopher J. DiMaio, Vladimir M. Kushnir, Mohamed Azab, Maria Ines Pinto-Sanchez, Bryan G. Sauer, Georgios I. Papachristou, Ji Zhu, Jordan Wood, Rajesh N. Keswani, Raman Muthusamy, Nancy L. Furey, Emad Qayed, Anish Patel, James Philip G. Esteban, Stephanie Mitchell, Judy A. Trieu, Jeong Yun Yang, Melissa Saul, Lujain Jaza, Rebekah E. Dixon, Mary K. West, Joseph F. LaComb, Fadi Odish, Swati Pawa, Luis F. Lara, Harsh K. Patel, Lauren Wakefield, Ali Zakaria, Rishi Pawa, Ambreen A. Merchant, Zachary L. Smith, Sachin Wani, Uchechi Okafor, Jason R. Taylor, Alexandria M. Lenyo, Nick Hajidiacos, Dhiraj Yadav, Ahmed I. Edhi, Cyrus R. Piraka, Field F. Willingham, Katherine A. Hanley, V. Mihajlo Gjeorgjievski, Olga C. Aroniadis, Anish A. Patel, Vikesh K. Singh, Nauzer Forbes, Collins O. Ordiah, Laura Mathews, Ashwinee Condon, Heiko Pohl, Vikram S. Kanagala, Eric D. Shah, William M. Tierney, Christopher Huang, Harminder Singh, Lilian Cruz, Darwin L. Conwell, Kelley Wood, Evan Mosier, Patrick S. Yachimski, Janak N. Shah, Eric F. Howard, Molly Caisse, Sheryl J. Korsnes, Emil Agarunov, Yueyang Zhang, Galina Diakova, Andrew Canakis, Bethany J. Wolf, Duyen T. Dang, Zahra Solati, Haley Nitchie, Rebecca L. Spitzer, Michael L. Volk, James M. Scheiman, Nicholas G. Brown, Richard S. Kwon, Amrita Sethi, John A. Damianos, Thomas Hollander, Olga Reykhart, Delia Calo, Zaid Imam, Robin B. Mendelsohn, E. Fogel, Don C. Rockey, Charlie Fox, Adrienne Lenhart, Selena Zhou, Ian Sloan, Laith H. Jamil, Akbar K. Waljee, M. I. Canto, Michael S. Bronze, Ayesha Kamal, Jennifer M. Kolb, Caroline G. McLeod, James Buxbaum, Casey L. Koza, Marc S. Piper, and Abhinav Tiwari

Subjects
Adult, Male, 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), medicine.drug_class, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Proton-pump inhibitor, Severity of Illness Index, Article, Internal medicine, Severity of illness, medicine, Humans, In patient, Aged, Retrospective Studies, Hepatology, business.industry, SARS-CoV-2, Gastroenterology, COVID-19, Proton Pump Inhibitors, Odds ratio, Middle Aged, Hospitalization, Histamine H2 Antagonists, Female, business
Published
2020

2. Digestive Manifestations in Patients Hospitalized with COVID-19

Author

Rosemary Nustas, Vikesh K. Singh, Nauzer Forbes, Judy A. Trieu, Molly Caisse, Fadi Odish, James M. Scheiman, Rebecca L. Spitzer, Delia Calo, Casey L. Koza, Janak N. Shah, Mary K. West, Kelley Wood, Yueyang Zhang, Amy Hosmer, Rebekah E. Dixon, Galina Diakova, Jason R. Taylor, Heiko Pohl, Weijing Tang, Jordan Wood, Laith H. Jamil, Abdul Haseeb, Vaishali Patel, Abhinav Tiwari, Amitabh Chak, Field F. Willingham, Joy M. Hutchinson, Melanie Mays, Stephanie Mitchell, Jeong Yun Yang, William M. Tierney, Soumil Patwardhan, Maria Ines Pinto-Sanchez, Collins O. Ordiah, Zaid Imam, Georgios I. Papachristou, Rishi Pawa, Millie Chau, Amar R. Deshpande, Akbar K. Waljee, Caroline G. McLeod, Natalia H. Zbib, B. Joseph Elmunzer, James Buxbaum, Dhiraj Yadav, Rajesh N. Keswani, Ayesha Kamal, Melissa Saul, Sheryl Korsnes, Kulwinder S. Dua, Luis F. Lara, Haley Nitchie, Don C. Rockey, Charlie Fox, Harminder Singh, Jennifer M. Kolb, Zachary L. Smith, Katherine A. Hanley, Bryan G. Sauer, Michael S. Bronze, Lujain Jaza, Mohamed Azab, V. Mihajlo Gjeorgjievski, Teldon B. Alford, Olga C. Aroniadis, Joseph F. LaComb, Michael L. Volk, Zahra Solati, Nick Hajidiacos, Benita K. Glamour, Gabriela Kuftinec, Selena Zhou, Vikram Kanagala, Marcia I. Canto, Ian Sloan, Duyen T. Dang, Evan L. Fogel, Valerie Durkalski, Swati Pawa, Marc S. Piper, Patrick Yachimski, Amrita Sethi, Andrew Canakis, Christopher J. DiMaio, Anish A. Patel, Adrienne Lenhart, Laura Mathews, Darwin L. Conwell, Alexandria M. Lenyo, Ali Zakaria, Eric F. Howard, Nicholas G. Brown, Olga Reykhart, Sachin Wani, Eric D. Shah, Lilian Cruz, Molly Orosey, Nancy Furey, Cyrus Piraka, Evan Mosier, Robin B. Mendelsohn, Ashwinee Condon, Uchechi Okafor, Andrew M. Aneese, Sunil Amin, Emad Qayed, Anish Patel, Vladimir Kushnir, Harsh K. Patel, Gulsum Anderson, Ambreen A. Merchant, Thomas Hollander, James Philip G. Esteban, Ahmed I. Edhi, Lydia D. Foster, Christopher S. Huang, Ji Zhu, Raman Muthusamy, Liam Hilson, Richard S. Kwon, Emil Agarunov, Lauren Wakefield, John A. Damianos, and Gail McNulty

Subjects
Adult, Male, Abdominal pain, medicine.medical_specialty, Adolescent, Nausea, Gastrointestinal Diseases, medicine.medical_treatment, digestive manifestations, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Interquartile range, Internal medicine, medicine, Humans, Aged, hepatic manifestations, Mechanical ventilation, Aged, 80 and over, Hepatology, business.industry, SARS-CoV-2, Confounding, Gastroenterology, COVID-19, Odds ratio, Middle Aged, Diarrhea, gastrointestinal symptoms, 030220 oncology & carcinogenesis, North America, Vomiting, 030211 gastroenterology & hepatology, Female, medicine.symptom, business
Abstract

Background & Aims The prevalence and significance of digestive manifestations in coronavirus disease 2019 (COVID-19) remain uncertain. We aimed to assess the prevalence, spectrum, severity, and significance of digestive manifestations in patients hospitalized with COVID-19. Methods Consecutive patients hospitalized with COVID-19 were identified across a geographically diverse alliance of medical centers in North America. Data pertaining to baseline characteristics, symptomatology, laboratory assessment, imaging, and endoscopic findings from the time of symptom onset until discharge or death were abstracted manually from electronic health records to characterize the prevalence, spectrum, and severity of digestive manifestations. Regression analyses were performed to evaluate the association between digestive manifestations and severe outcomes related to COVID-19. Results A total of 1992 patients across 36 centers met eligibility criteria and were included. Overall, 53% of patients experienced at least 1 gastrointestinal symptom at any time during their illness, most commonly diarrhea (34%), nausea (27%), vomiting (16%), and abdominal pain (11%). In 74% of cases, gastrointestinal symptoms were judged to be mild. In total, 35% of patients developed an abnormal alanine aminotransferase or total bilirubin level; these were increased to less than 5 times the upper limit of normal in 77% of cases. After adjusting for potential confounders, the presence of gastrointestinal symptoms at any time (odds ratio, 0.93; 95% CI, 0.76–1.15) or liver test abnormalities on admission (odds ratio, 1.31; 95% CI, 0.80–2.12) were not associated independently with mechanical ventilation or death. Conclusions Among patients hospitalized with COVID-19, gastrointestinal symptoms and liver test abnormalities were common, but the majority were mild and their presence was not associated with a more severe clinical course.

Published
2020

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