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Copyright of Assiut Veterinary Medical Journal is the property of Egyptian National Agricultural Library (ENAL) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Trichinella spiralis infection is a food‐borne zoonotic disease caused by nematodes that dwell in the tissues, presenting a significant public health concern. This study aimed to evaluate the effectiveness of different treatments including silver nanoparticles (AgNPs), myrrh biosynthesized AgNPs "AgNPs synthesized using plant‐based green technologies", myrrh extract, and myrrh essential oil, as alternative treatments against T. spiralis infection. Parasitological, histopathological, and cytotoxicity assessments were conducted to investigate the effects of various concentrations of these treatments in reducing the populations of adult worms and larvae during both the intestinal and muscular phases of T. spiralis‐infected mice. The results showed that the highest antihelminthic efficacy against the intestinal phase of T. spiralis was achieved by myrrh extract (86.66%), followed closely by AgNPs (84.96%) and myrrh AgNPs (82.51%) at higher concentrations (800 mg/kg for myrrh extract, 40 μg/mL for AgNPs, and 40 μg/mL for myrrh AgNPs). While the group treated with myrrh essential oil showed the lowest percentage of adult reduction (78.14%). However, all treatments demonstrated comparable effects in reducing the larvae population in the muscle phase. Histopathological examination of the tissues revealed compelling evidence of the effectiveness of AgNPs, particularly when prepared with myrrh. Additionally, a comprehensive assessment of the cytotoxicity of AgNPs indicated low toxicity levels. This study supports that AgNPs synthesized using plant‐based green technologies hold therapeutic potential for the treatment of T. spiralis infection. These findings present a promising avenue for the development of novel antiparasitic drugs that are both effective and safe. Research Highlights: Myrrh extract has the highest antihelminthic efficacy against the intestinal phase of T. spiralis.Histopathological examination of the tissues revealed compelling evidence of the effectiveness of AgNPs, particularly when prepared with myrrh.During intestinal phase of T. spiralis, varying levels of nanoparticle precipitation were detected in the liver, brain, lung, and intestine. During the muscular phase, the highest amount of AgNPs precipitation was detected in the liver, followed by the brain, and lung. [ABSTRACT FROM AUTHOR]

Cats, as widely embraced companions in diverse environments, face significant health threats due to infection by ectoparasites. The present study investigates the prevalence of ectoparasite infestations in domestic cats (Felis catus) in Giza Governorate, Egypt. Spanning from December 2022 to November 2023, the study included 400 samples of diverse feline populations. Fleas and ear mites were detected in 20.75% and 11.25% of the examined cats, respectively. While ticks and myiasis were observed in 0.5% for each. Clinical manifestations and morphological structures of the detected parasites were documented. Moreover, the research integrates molecular characterization, utilizing the COI gene for Sarcophaga species identification. The study also analyzed risk factors, adjusting for age, sex, and season, revealing variations in infestation rates. Cats under one year old exhibited the highest infestation rate (48.35%). Seasonal variation showed the highest prevalence in autumn, followed by summer and winter, with a decline in spring. This survey study provides valuable insights into ectoparasite infestations in domestic cats to serve as a pivotal step toward promoting cat welfare and safeguarding public health. [ABSTRACT FROM AUTHOR]

Copyright of Assiut Veterinary Medical Journal is the property of Egyptian National Agricultural Library (ENAL) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this work, using Dissipative Particle Dynamics simulations, we provide fundamental insights into the self-assembly of nanoparticles (NPs) on droplet surfaces in an oil-in-water emulsion. We highlight the effect of particle size on the arrangement of NPs for different interparticle interactions. NPs of two different sizes were considered. In general, when the NP–NP interaction is changed from repulsive to attractive, a transition in the NP arrangement occurs from weekly-connected networks to clusters of NPs separated by particle-free domains. When NP–NP interactions are strongly attractive, NPs yield small 3D aggregates on the droplet surface. These arrangements seem to agree with experimental observations reported in the literature. In addition, our simulations suggest that small NPs are able to diffuse more easily on the droplet surface, which leads to prompt self-organisation, while large NPs are more likely to form metastable structures, perhaps because of slow mobility and strong adsorption to the interface. Our analysis suggests that thermal fluctuations could provide the activation energy for the small NPs to escape local minima in the free energy landscape. The results obtained for systems containing NPs of two sizes provide evidence of size segregation on the droplet surface, which could be useful when NP self-assemblies are used, for example, to template supra-molecular materials. However, analysis of the simulated trajectories suggests that the results depend strongly on the initial configuration, as the larger NPs seem to impose barriers for the small NPs to adsorb and diffuse on the droplet surface. [ABSTRACT FROM AUTHOR]

Copyright of Assiut Veterinary Medical Journal is the property of Egyptian National Agricultural Library (ENAL) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Assiut Veterinary Medical Journal is the property of Egyptian National Agricultural Library (ENAL) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)