315 results on '"Kügler, Sebastian"'
Search Results
2. Human serum-derived α-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons
3. Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants
4. Syntenin-knock out reduces exosome turnover and viral transduction
5. Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery
6. Neuronal Trans-differentiation by Transcription Factors Ascl1 and Nurr1: Induction of a Dopaminergic Neurotransmitter Phenotype in Cortical GABAergic Neurons
7. Probing the function of glycinergic neurons in the mouse respiratory network using optogenetics
8. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration
9. S-SCAM is essential for synapse formation.
10. Vti1b promotes TRPV1 sensitization during inflammatory pain
11. Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors
12. A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice
13. Fibroblast growth factor 9 (FGF9)‐mediated neurodegeneration: Implications for progressive multiple sclerosis?
14. Lentiviral Delivery of miR-133b Improves Functional Recovery After Spinal Cord Injury in Mice
15. Neuropeptide Y stimulates autophagy in hypothalamic neurons
16. Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
17. Depletion of microglia and inhibition of exosome synthesis halt tau propagation
18. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
19. Publisher Correction: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration
20. Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex
21. Dendritic Degeneration, Neurovascular Defects, and Inflammation Precede Neuronal Loss in a Mouse Model for Tau-Mediated Neurodegeneration
22. Thalamocortical Connections Drive Intracortical Activation of Functional Columns in the Mislaminated Reeler Somatosensory Cortex
23. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease
24. AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury
25. Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons
26. A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity
27. Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons
28. Pre-existing immunity to adeno-associated virus (AAV)2 limits transgene expression following intracerebral AAV2-based gene delivery in a 6-hydroxydopamine model of Parkinsonʼs disease
29. Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models
30. Optogenetic stimulation of the auditory pathway
31. Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis
32. Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo
33. Reply
34. β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons
35. α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals.
36. Improved high-capacity adenoviral vectors for high-level neuron-restricted gene transfer to the CNS
37. Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease
38. Chronic imaging of cortical sensory map dynamics using a genetically encoded calcium indicator
39. Evaluation of long-term upregulation of Calbindin D28K as a preventive approach for ischaemic stroke
40. Ehlers-Danlos syndrome type VI: lysyl hydroxylase deficiency due to a novel point mutation (W612C)
41. BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity
42. Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release
43. Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
44. Adeno-associated virus-mediated L1 expression promotes functional recovery after spinal cord injury
45. The human vigilin gene: identification, chromosomal localization and expression pattern
46. Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo
47. Increased protein expression from adenoviral shuttle plasmids and vectors by insertion of a small chimeric intron sequence
48. Excess Bcl-XL increases the intrinsic growth potential of adult CNS neurons in vitro☆
49. Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo
50. Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals
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