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122 results on '"Jostins, Luke"'

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1. HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

2. Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

3. A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

4. An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease

6. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

12. Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

13. Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

16. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

17. A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

18. GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome

19. A global reference for human genetic variation

20. Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

21. Fine-mapping inflammatory bowel disease loci to single-variant resolution

22. An integrated map of genetic variation from 1,092 human genomes

23. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

24. Dense fine-mapping study identifies novel disease loci and implicates coding and non-coding variation in primary biliary cirrhosis risk: 2021

25. A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

27. A map of human genome variation from population-scale sequencing

29. Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

30. Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

32. Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis.

33. Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

34. Inferring genotyping error rates from genotyped trios

35. Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

36. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

37. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

38. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.

39. Using Genetic Prediction from Known Complex Disease Loci to Guide the Design of Next-Generation Sequencing Experiments.

41. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.

42. Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets.

43. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

44. Reverse engineering a gene network using an asynchronous parallel evolution strategy.

45. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

46. High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

48. Graphical model selection for Gaussian conditional random fields in the presence of latent variables : theory and application to genetics

49. Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

50. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

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