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221 results on '"Johnstone, Alan"'

5. Plaster cast versus functional brace for non-surgical treatment of Achilles tendon rupture (UKSTAR): a multicentre randomised controlled trial and economic evaluation

Author

Abdallah, Amr, Ballal, Moez, Ballester, Jordi, Beastall, James, Bhattacharya, Rajarshi, Burrt, Simon, Deakin, Mark, Deol, Rupe, Dramis, Asterios, El-Kawy, Sameh, Eyre, Jason, Forder, Justin, Ghosh, Avijeet, Guha, Anhijit, Hancock, Nicholas, Harrold, Fraser, Harwood, Paul, Hull, Peter, Johnstone, Alan, Kapoor, Sandeep, Karagkevrekis, Babis, Kelly, Andrew, Kurdy, Nasser, Kurup, Harish, Lyle, Victoria, Madan, Sanjeev, Madeley, Jane, Mahmood, Ansar, Malik, Atif, McAndrew, Andrew, Mishra, Viren, Modi, Nitin, Nanda, Rajesh, Reichert, Ines, Reissis, Nikos, Sampalli, Sridhar, Scott, Andrea, Walter, Richard, Westwood, Mark, Costa, Matthew L, Achten, Juul, Marian, Ioana R, Dutton, Susan J, Lamb, Sarah E, Ollivere, Benjamin, Maredza, Mandy, Petrou, Stavros, and Kearney, Rebecca S

Published
2020
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44. Can general practice trainees engage with leadership activities during their GP training placements? - An evaluation of an intervention in South East Scotland.

Author

Denney, Meiling and Johnstone, Alan

Subjects
*CLINICAL competence, *FAMILY medicine, *FOCUS groups, *HOSPITAL medical staff, *LEADERSHIP, *SELF-efficacy, *SURVEYS, *CLINICAL supervision, *EVALUATION of human services programs, *EDUCATION
Abstract

Leadership is one of the GMC's Generic Professional Capabilities for all medical specialties, but engagement in leadership activities is not currently routinely built into general practice (GP) training. We explored whether GP trainees in their first year of speciality training (ST1) could engage with a leadership activity in their practice placement. GP trainees were invited to participate in a voluntary leadership activity, with a small menu of optional activities to choose from. Evaluation was through electronic survey of trainees and educational supervisors (ESs) before and after the GP placement, and through trainee focus groups after the placement. 89 trainees and 191 supervisors were surveyed at the start of the trial. Trainees felt supported by supervisors and practice team members. Both groups felt that leadership skills were important for a trainee's future career. Supervisors placed more emphasis on this than trainees. Identified barriers included lack of protected time, other training priorities, lack of empowerment, and personal issues. Most trainees and their supervisors felt that a leadership activity was possible during the first year of general practice training. More work needs to be done to see if these results are generalisable to trainees across demographic subgroups, and in other years of training. [ABSTRACT FROM AUTHOR]

Published
2019
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47. Endogenously produced nitric oxide inhibits endothelial cell growth as demonstrated using novel antisense cell lines

Author

Cartwright, Judith E, Johnstone, Alan P, and Whitley, Guy St J

Subjects
Mice, Cell Death, Papers, Animals, RNA, Antisense, Endothelium, Vascular, Nitric Oxide Synthase, Blotting, Northern, Nitric Oxide, Transfection, Cell Division, Cells, Cultured
Abstract

Proliferation of endothelial cells is a vital component of vascular repair and angiogenesis. The endothelial cell mediator, nitric oxide (NO) has been reported both to inhibit and to promote endothelial cell proliferation. In this study we have generated cell lines which constitutively express antisense RNA to a region of inducible nitric oxide synthase (iNOS) from a murine endothelial cell line, sEnd-1. In response to stimulation with lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) these antisense cells had no detectable RNA for endogenous iNOS, barely detectable iNOS protein and produced 82% less NO than did the control transfected line. Stimulation of the control transfected line caused significant NO production and inhibition of cell growth whereas for the antisense line, producing little NO in response to stimulation, proliferation remained the same as for unstimulated cells. No differences in cell death were observed between unstimulated and LPS/IFN-gamma stimulated cells. The data presented in this study directly demonstrate that NO derived endogenously from iNOS inhibits proliferation of endothelial cells. This approach overcomes problems in other studies where NO donors or non-isoform specific inhibitors of NO synthase have been used.

Published
2000

49. TELENOR MARITIME SMOOTHS PATH TO IMPROVED DATA MANAGEMENT.

Author

Johnstone, Alan

Subjects
DATA management
Abstract

The article focuses on Telenor Maritime's Unified Hosting Service (UHS), a novel approach to onboard digitalization for vessels in the maritime industry. Topics discussed include the need for efficient and secure data management, the benefits of a vendor-neutral platform, and the platform's potential applications, including compliance with environmental standards and its role in enabling private 5G networks for enhanced security.

Published
2023

50. FINANCING THE FUTURE.

Author

Johnstone, Alan

Subjects
ARTIFICIAL intelligence
Abstract

The article discusses the role of finance in enabling the sustainable energy transition of the maritime industry. Emphasis is given on the need for investment to transform ocean industries. It shows the support of Norweigian bank DNB for shipping's sustainable transition through the Poseidon Principles, Responsible Ship Recycling Standards, and Getting to Zero Coalition. In informs about DNB's development and marketing of sustainably linked loans and bonds and its Energy Transition Solutions.

Published
2023

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