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Your search keyword '"JENKINS, DAVID J. A."' showing total 717 results
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717 results on '"JENKINS, DAVID J. A."'

5. Association of glycaemic index and glycaemic load with type 2 diabetes, cardiovascular disease, cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants

Author

Balachandran, Bashyam, Zurbau, Andreea, Wang, Xunan, Liang, Fred, Yang, Wanning, Jenkins, David J A, Willett, Walter C, Yusuf, Salim, Hu, Frank B, Glenn, Andrea J, Liu, Simin, Mente, Andrew, Miller, Victoria, Bangdiwala, Shrikant I, Gerstein, Hertzel C, Sieri, Sabina, Ferrari, Pietro, Patel, Alpa V, McCullough, Marjorie L, Le Marchand, Loïc, Freedman, Neal D, Loftfield, Erikka, Sinha, Rashmi, Shu, Xiao-Ou, Touvier, Mathilde, Sawada, Norie, Tsugane, Shoichiro, van den Brandt, Piet A, Shuval, Kerem, Khan, Tauseef Ahmad, Paquette, Melanie, Sahye-Pudaruth, Sandhya, Patel, Darshna, Siu, Teenie Fei Yi, Srichaikul, Korbua, Kendall, Cyril W C, and Sievenpiper, John L

Published
2024
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8. Chromosome-scale Echinococcus granulosus (genotype G1) genome reveals the Eg95 gene family and conservation of the EG95-vaccine molecule

Author

Korhonen, Pasi K., Kinkar, Liina, Young, Neil D., Cai, Huimin, Lightowlers, Marshall W., Gauci, Charles, Jabbar, Abdul, Chang, Bill C. H., Wang, Tao, Hofmann, Andreas, Koehler, Anson V., Li, Junhua, Li, Jiandong, Wang, Daxi, Yin, Jiefang, Yang, Huanming, Jenkins, David J., Saarma, Urmas, Laurimäe, Teivi, Rostami-Nejad, Mohammad, Irshadullah, Malik, Mirhendi, Hossein, Sharbatkhori, Mitra, Ponce-Gordo, Francisco, Simsek, Sami, Casulli, Adriano, Zait, Houria, Atoyan, Hripsime, de la Rue, Mario Luiz, Romig, Thomas, Wassermann, Marion, Aghayan, Sargis A., Gevorgyan, Hasmik, Yang, Bicheng, and Gasser, Robin B.

Published
2022
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12. The Portfolio Diet and HbA1c in Adults Living with Type 2 Diabetes Mellitus: A Patient-Level Pooled Analysis of Two Randomized Dietary Trials.

Author

Kavanagh, Meaghan E., Back, Songhee, Chen, Victoria, Glenn, Andrea J., Viscardi, Gabrielle, Houshialsadat, Zeinab, Sievenpiper, John L., Kendall, Cyril W. C., Jenkins, David J. A., and Chiavaroli, Laura

Abstract

(1) Background: The Portfolio Diet, a dietary pattern of cholesterol-lowering foods, is also rich in low glycemic index (GI) foods. While strong evidence supports clinically meaningful reductions in cholesterol, evidence on the relationship between the Portfolio Diet and diabetes management is lacking. (2) Objective: To evaluate the relationship between the Portfolio Diet and glycated hemoglobin (HbA1c) as a determinant of glycemic control among adults living with type 2 diabetes mellitus (T2DM). (3) Methods: Patient-level data was pooled from two randomized dietary trials of low glycemic index interventions compared to high cereal fibre control diets in adults living with T2DM where HbA1c was collected (clinicaltrials.gov identifiers: NCT00438698, NCT00438698). Dietary exposure was assessed using weighed 7-day diet records. Adherence to the Portfolio Diet and its pillars (nuts and seeds, plant protein, viscous fibre, plant sterols, monounsaturated fatty acid [MUFA] oils) was determined using the validated clinical Portfolio Diet Score (c-PDS). Multiple linear regression was used to assess the association between change in the c-PDS and change in HbA1c over 6-months with covariate adjustments. (4) Results: A total of 267 participants, predominantly White (67%) and male (63%), were included, with a mean ± standard error age of 62 ± 0.5 years, baseline BMI of 30.2 ± 0.3 kg/m2, HbA1c of 7.08 ± 0.03%, and a c-PDS of 4.1 ± 0.3 points out of 25. Change in the c-PDS was significantly associated with a change in HbA1c (β: −0.04% per point, 95% CI: −0.07, −0.02, p = 0.001). A 7.5-point (30%) increase in the c-PDS was associated with a 0.3% reduction in HbA1c. Of the individual pillars, a 1-point change in nut and seeds intake (β: −0.07%, 95% CI: −0.12, −0.02, p = 0.009) or in plant protein intake (β: −0.11%, 95% CI: −0.18, −0.03, p = 0.009) was associated with a change in HbA1c. Further analysis of plant protein intake revealed that an increase in dietary pulse intake, a particularly low-GI food, was significantly associated with a reduction in HbA1c (β: −0.24% per 1-cup points cooked pulses (226 g) or 2 c-PDS points, 95% CI: −0.45, −0.03, p = 0.028). (5) Conclusions: Among adults living with T2DM, the Portfolio Diet was associated with lower HbA1c over a 6-month period, predominantly driven by two pillars: nuts and seeds and plant protein, particularly dietary pulses. These data have implications for including the Portfolio Diet in dietary recommendations for glycemic control in T2DM. A trial demonstrating the direct causal effect of the Portfolio Diet in a diverse group is warranted. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Associations between Dietary Pulses Alone or with Other Legumes and Cardiometabolic Disease Outcomes: An Umbrella Review and Updated Systematic Review and Meta-analysis of Prospective Cohort Studies

Author

Viguiliouk, Effie, Glenn, Andrea J, Nishi, Stephanie K, Chiavaroli, Laura, Seider, Maxine, Khan, Tauseef, Bonaccio, Marialaura, Iacoviello, Licia, Mejia, Sonia Blanco, Jenkins, David J A, Kendall, Cyril W C, Kahleová, Hana, Rahelić, Dario, Salas-Salvadó, Jordi, and Sievenpiper, John L

Published
2019
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19. Common Variants in Lipid Metabolism–Related Genes Associate with Fat Mass Changes in Response to Dietary Monounsaturated Fatty Acids in Adults with Abdominal Obesity

Author

Hammad, Shatha S, Eck, Peter, Sihag, Jyoti, Chen, Xiang, Connelly, Philip W, Lamarche, Benoît, Couture, Patrick, Guay, Valérie, Maltais-Giguère, Julie, West, Sheila G, Kris-Etherton, Penny M, Bowen, Kate J, Jenkins, David J A, Taylor, Carla G, Perera, Danielle, Wilson, Angela, Castillo, Sandra, Zahradka, Peter, and Jones, Peter J H

Published
2019
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23. Adherence to a Cholesterol-Lowering Diet and the Risk of Pancreatic Cancer: A Case–Control Study.

Author

Di Maso, Matteo, Augustin, Livia S. A., Jenkins, David J. A., Crispo, Anna, Toffolutti, Federica, Negri, Eva, La Vecchia, Carlo, Ferraroni, Monica, and Polesel, Jerry

Abstract

Background: Pancreatic cancer risk has been associated with increased serum cholesterol level, which is in turn partially influenced by diet. This study aimed at evaluating the association between pancreatic cancer risk and the adherence to a plant-based cholesterol-lowering diet. Methods: Data were derived from an Italian case–control study including 258 pancreatic cancer patients and 551 controls. The cholesterol-lowering diet score was based on seven components: high intakes of (i) non-cellulosic polysaccharides (a proxy of viscous fibers), (ii) monounsaturated fatty acids, (iii) legumes, and (iv) seeds/corn oils (a proxy of phytosterols); and low intakes of (v) saturated fatty acids, (vi) dietary cholesterol, and (vii) food with a high glycemic index. The score was calculated adding one point for each fulfilled component, thus ranging from zero (no adherence) to seven (complete adherence). The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated through the logistic regression model. Results: Scores 5–7 were associated with reduced cancer risk (OR = 0.30; 95% CI: 0.18–0.52) compared to scores 0–2. Conclusions: Adherence to a plant-based cholesterol-lowering diet was associated with a reduced risk of pancreatic cancer. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Distinguishing Echinococcus granulosus sensu stricto genotypes G1 and G3 with confidence: A practical guide

Author

Kinkar, Liina, Laurimäe, Teivi, Acosta-Jamett, Gerardo, Andresiuk, Vanessa, Balkaya, Ibrahim, Casulli, Adriano, Gasser, Robin B., González, Luis Miguel, Haag, Karen L., Zait, Houria, Irshadullah, Malik, Jabbar, Abdul, Jenkins, David J., Manfredi, Maria Teresa, Mirhendi, Hossein, M'rad, Selim, Rostami-Nejad, Mohammad, Oudni-M'rad, Myriam, Pierangeli, Nora Beatriz, Ponce-Gordo, Francisco, Rehbein, Steffen, Sharbatkhori, Mitra, Kia, Eshrat Beigom, Simsek, Sami, Soriano, Silvia Viviana, Sprong, Hein, Šnábel, Viliam, Umhang, Gérald, Varcasia, Antonio, and Saarma, Urmas

Published
2018
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25. Global phylogeography and genetic diversity of the zoonotic tapeworm Echinococcus granulosus sensu stricto genotype G1

Author

Kinkar, Liina, Laurimäe, Teivi, Acosta-Jamett, Gerardo, Andresiuk, Vanessa, Balkaya, Ibrahim, Casulli, Adriano, Gasser, Robin B., van der Giessen, Joke, González, Luis Miguel, Haag, Karen L., Zait, Houria, Irshadullah, Malik, Jabbar, Abdul, Jenkins, David J., Kia, Eshrat Beigom, Manfredi, Maria Teresa, Mirhendi, Hossein, M'rad, Selim, Rostami-Nejad, Mohammad, Oudni-M'rad, Myriam, Pierangeli, Nora Beatriz, Ponce-Gordo, Francisco, Rehbein, Steffen, Sharbatkhori, Mitra, Simsek, Sami, Soriano, Silvia Viviana, Sprong, Hein, Šnábel, Viliam, Umhang, Gérald, Varcasia, Antonio, and Saarma, Urmas

Published
2018
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26. Diets Low in Saturated Fat with Different Unsaturated Fatty Acid Profiles Similarly Increase Serum-Mediated Cholesterol Efflux from THP-1 Macrophages in a Population with or at Risk for Metabolic Syndrome: The Canola Oil Multicenter Intervention Trial

Author

Liu, Xiaoran, Garban, Josephine, Jones, Peter J, Vanden Heuvel, Jack, Lamarche, Benoît, Jenkins, David J, Connelly, Philip W, Couture, Patrick, Pu, Shuaihua, Fleming, Jennifer A, West, Sheila G, and Kris-Etherton, Penny M

Published
2018
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36. A Plant-Based Cholesterol-Lowering Diet Score Correlates with Serum LDL-Cholesterol Levels.

Author

Polesel, Jerry, Di Maso, Matteo, Esposito, Giovanna, Vitale, Sara, Palumbo, Elvira, Porciello, Giuseppe, Calabrese, Ilaria, Minopoli, Anita, Grilli, Bruna, Cavalcanti, Ernesta, Serraino, Diego, Celentano, Egidio, Jenkins, David J. A., and Augustin, Livia S. A.

Abstract

Background: A cholesterol-lowering diet score was previously developed for epidemiological studies; its association with serum lipid profile was not confirmed yet. Methods: The score was developed as an adaptation of the dietary portfolio for cholesterol reduction, assigning one point for adherence to seven dietary indicators and ranging from 0 (null adherence) to 7 (highest adherence). The score was calculated for breast cancer patients enrolled in the DEDiCa study using a 7-day food record; serum lipid profile, including total and low-density lipoprotein cholesterol (LDL-C), was evaluated in serum at baseline. Results: Patients with the highest adherence to the cholesterol-lowering diet (i.e., score ≥ 4) reported lower LDL-C level than women with score 0–1 (median: 107 mg/dL and 122 mg/dL, respectively; p < 0.01). The proportion of women with LDL-C above the recommended limit of 116 mg/dL was 60.0% with score 0–1 and 42.6% with score ≥4. Although the score directly correlates with consumption of foods from vegetal sources, it was mildly associated with the healthful plant-based diet index (r-Spearman = 0.51) and the Mediterranean Diet Adherence Screener (r-Spearman = 0.30) Conclusions: These results provide experimental evidence that the cholesterol-lowering diet score is capable of detecting a specific plant-based dietary pattern that affects circulating cholesterol levels. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Fructose-containing food sources and blood pressure: A systematic review and meta-analysis of controlled feeding trials.

Author

Liu, Qi, Chiavaroli, Laura, Ayoub-Charette, Sabrina, Ahmed, Amna, Khan, Tauseef A., Au-Yeung, Fei, Lee, Danielle, Cheung, Annette, Zurbau, Andreea, Choo, Vivian L., Mejia, Sonia Blanco, de Souza, Russell J., Wolever, Thomas M. S., Leiter, Lawrence A., Kendall, Cyril W. C., Jenkins, David J. A., and Sievenpiper, John L.

Subjects
BLOOD pressure, CALORIC content of foods, TRIALS (Law), FRUIT juices, BLOOD sugar, SUGARS
Abstract

Whether food source or energy mediates the effect of fructose-containing sugars on blood pressure (BP) is unclear. We conducted a systematic review and meta-analysis of the effect of different food sources of fructose-containing sugars at different levels of energy control on BP. We searched MEDLINE, Embase and the Cochrane Library through June 2021 for controlled trials ≥7-days. We prespecified 4 trial designs: substitution (energy matched substitution of sugars); addition (excess energy from sugars added); subtraction (excess energy from sugars subtracted); and ad libitum (energy from sugars freely replaced). Outcomes were systolic and diastolic BP. Independent reviewers extracted data. GRADE assessed the certainty of evidence. We included 93 reports (147 trial comparisons, N = 5,213) assessing 12 different food sources across 4 energy control levels in adults with and without hypertension or at risk for hypertension. Total fructose-containing sugars had no effect in substitution, subtraction, or ad libitum trials but decreased systolic and diastolic BP in addition trials (P<0.05). There was evidence of interaction/influence by food source: fruit and 100% fruit juice decreased and mixed sources (with sugar-sweetened beverages [SSBs]) increased BP in addition trials and the removal of SSBs (linear dose response gradient) and mixed sources (with SSBs) decreased BP in subtraction trials. The certainty of evidence was generally moderate. Food source and energy control appear to mediate the effect of fructose-containing sugars on BP. The evidence provides a good indication that fruit and 100% fruit juice at low doses (up to or less than the public health threshold of ~10% E) lead to small, but important reductions in BP, while the addition of excess energy of mixed sources (with SSBs) at high doses (up to 23%) leads to moderate increases and their removal or the removal of SSBs alone (up to ~20% E) leads to small, but important decreases in BP in adults with and without hypertension or at risk for hypertension. Trial registration: Clinicaltrials.gov: NCT02716870. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Dried Fruits: Bioactives, Effects on Gut Microbiota, and Possible Health Benefits—An Update.

Author

Alasalvar, Cesarettin, Chang, Sui Kiat, Kris-Etherton, Penny M., Sullivan, Valerie K., Petersen, Kristina S., Guasch-Ferré, Marta, and Jenkins, David J. A.

Abstract

Dried fruits contain many bioactive compounds broadly classified as phytochemicals including phenolics, flavonoids, carotenoids, proanthocyanidins, stilbenes, chalcones/dihydrochalcones, and phytoestrogens. These compounds have antioxidant effects that may benefit health. Dried fruits are also a diverse group of foods with varying fibre contents. The evaluation of the biological activity of these bioactive compounds, including their bioaccessibility and bioavailability, may contribute to the understanding of the health effects of dried fruits. Limited evidence suggests that dried fruits (raisins, cranberries, dates, and prunes) affect human gut microbiota composition in a potentially beneficial manner (in terms of effects on Bifidobacteria, Faecalibacterium prausnitzii, Lactobacillus, Ruminococcaceae, Klebsiella spp., and Prevotella spp.). There is little epidemiological evidence about the association of dried fruit consumption with cardiovascular disease incidence and mortality, as well as the risk of type 2 diabetes or obesity. Clinical trial evidence for the effects of dried fruit consumption on cardiovascular risk factors, including glycaemic control, is mixed. Clinical trial evidence suggests prunes might preserve bone mineral density in postmenopausal women. Consumption of dried fruits is associated with higher-quality diets. Studies are needed to increase our understanding of the health effects of dried fruits and the underlying biological mechanisms. [ABSTRACT FROM AUTHOR]

Published
2023
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