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Your search keyword '"Ida M. Onorato"' showing total 4 results
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4 results on '"Ida M. Onorato"'

1. DNA Fingerprinting of Mycobacterium tuberculosis Isolates from Epidemiologically Linked Case Pairs

Author

Diane E. Bennett, Ida M. Onorato, Barbara A. Ellis, Jack T. Crawford, Barbara Schable, Robert Byers, J. Steve Kammerer, and Christopher R. Braden

Subjects
Mycobacterium tuberculosis, DNA fingerprinting, molecular epidemiology, contact investigation, United States, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

DNA fingerprinting was used to evaluate epidemiologically linked case pairs found during routine tuberculosis (TB) contact investigations in seven sentinel sites from 1996 to 2000. Transmission was confirmed when the DNA fingerprints of source and secondary cases matched. Of 538 case pairs identified, 156 (29%) did not have matching fingerprints. Case pairs from the same household were no more likely to have confirmed transmission than those linked elsewhere. Case pairs with unconfirmed transmission were more likely to include a smear-negative source case (odds ratio [OR] 2.0) or a foreign-born secondary case (OR 3.4) and less likely to include a secondary case

Published
2002
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2. National Tuberculosis Genotyping and Surveillance Network: Design and Methods

Author

Jack T. Crawford, Christopher R. Braden, Barbara A. Schable, and Ida M. Onorato

Subjects
Mycobacterium tuberculosis, strain typing, surveillance, United States, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

The National Tuberculosis Genotyping and Surveillance Network was established in 1996 to perform a 5-year, prospective study of the usefulness of genotyping Mycobacterium tuberculosis isolates to tuberculosis control programs. Seven sentinel sites identified all new cases of tuberculosis, collected information on patients and contacts, and obtained patient isolates. Seven genotyping laboratories performed DNA fingerprinting analysis by the international standard IS6110 method. BioImage Whole Band Analyzer software was used to analyze patterns, and distinct patterns were assigned unique designations. Isolates with six or fewer bands on IS6110 patterns were also spoligotyped. Patient data and genotyping designations were entered in a relational database and merged with selected variables from the national surveillance database. In two related databases, we compiled the results of routine contact investigations and the results of investigations of the relationships of patients who had isolates with matching genotypes. We describe the methods used in the study.

Published
2002
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3. Improving the representativeness of behavioral and clinical surveillance for persons with HIV in the United States: the rationale for developing a population-based approach

Author

Eve D. Mokotoff, Alice Kroliczak, Ronald O. Valdiserri, Raul A. Romaguera, Patrick S. Sullivan, Robert S. Janssen, A. D. McNaghten, Mitchell I. Wolfe, Allyn K. Nakashima, and Ida M. Onorato

Subjects
Gerontology, medicine.medical_specialty, Health Behavior, Psychological intervention, Human immunodeficiency virus (HIV), Public Health and Epidemiology/Infectious Diseases, lcsh:Medicine, HIV Infections, Population based, Institute of medicine, Public Health and Epidemiology/Health Policy, medicine.disease_cause, Representativeness heuristic, Acquired immunodeficiency syndrome (AIDS), Preventive Health Services, medicine, Humans, lcsh:Science, Multidisciplinary, business.industry, lcsh:R, HIV, Infectious Diseases/HIV Infection and AIDS, medicine.disease, United States, Treatment utilization, Family medicine, Population Surveillance, lcsh:Q, business, Resource utilization, Public Health and Epidemiology/Social and Behavioral Determinants of Health, Research Article
Abstract

The need for a new surveillance approach to understand the clinical outcomes and behaviors of people in care for HIV evolved from the new challenges for monitoring clinical outcomes in the HAART era, the impact of the epidemic on an increasing number of areas in the US, and the need for representative data to describe the epidemic and related resource utilization and needs. The Institute of Medicine recommended that the Centers for Disease Control and Prevention and the Heath Resources and Services Administration coordinate efforts to survey a random sample of HIV-infected persons in care, in order to more accurately measure the need for prevention and care services. The Medical Monitoring Project (MMP) was created to meet these needs. This manuscript describes the evolution and design of MMP, a new nationally representative clinical outcomes and behavioral surveillance system, and describes how MMP data will be used locally and nationally to identify care and treatment utilization needs, and to plan for prevention interventions and services.

Published
2007

4. The fall after the rise: Tuberculosis in the United States, 1991 through 1994

Author

Matthew T. McKenna, Ida M. Onorato, Eugene McCray, Kenneth G. Castro, and Jeffrey L. Jones

Subjects
Adult, Male, medicine.medical_specialty, Tuberculosis, Adolescent, Disease, Acquired immunodeficiency syndrome (AIDS), Epidemiology, medicine, Humans, Child, Aged, business.industry, Incidence (epidemiology), Public health, Public Health, Environmental and Occupational Health, Emigration and Immigration, Middle Aged, medicine.disease, United States, Confidence interval, Social Class, Child, Preschool, Population Surveillance, Patient Compliance, Regression Analysis, Sputum, Female, Morbidity, medicine.symptom, business, Demography, Research Article
Abstract

OBJECTIVES: Factors associated with decreases in tuberculosis cases observed in the United States in 1993 and 1994 were analyzed. METHODS: Changes in case counts reported to the national surveillance system were evaluated by dividing the number of incident cases of TB reported in 1993 and 1994 by the number of cases reported in 1991 and 1992 and stratifying these ratios by demographic factors, AIDS incidence, and changes in program performance. RESULTS: Case counts decreased from 52,956 in 1991 and 1992 to 49,605 in 1993 and 1994 (case count ratio = 0.94, 95% confidence interval [CI] = 0.93, 0.95). The decrease, confined to US-born patients, was generally associated with AIDS incidence and improvements in completion of therapy, conversion of sputum, and increases in the number of contacts identified per case. CONCLUSIONS: Recent TB epidemiology patterns suggest that improvements in treatment and control activities have contributed to the reversal in the resurgence of this disease in US-born persons. Continued success in preventing the occurrence of active TB will require sustained efforts to ensure appropriate treatment of cases.

Published
1998

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