17 results on '"Iacobelli, B. D."'
Search Results
2. Short versus mid-long-term outcome of transanal irrigation in children with spina bifida and anorectal malformations
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Ausili, Emanuele, Marte, A., Brisighelli, G., Midrio, P., Mosiello, G., La Pergola, E., Lombardi, L., Iacobelli, B. D., Caponcelli, E., Meroni, M., Leva, E., and Rendeli, C.
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- 2018
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3. Giant rapidly involuting congenital haemangioma and Kasabach‐Merritt phenomenon: A potentially underhanded trap.
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Diociaiuti, A., Bersani, I., Dotta, A., Braguglia, A., Di Pede, A., Iacobelli, B. D., Pugnaloni, F., Guido, M., Di Fabio, S., Toscano, A., Conforti, A., Bagolan, P., and El Hachem, M.
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DECISION making ,BLOOD coagulation disorders ,CONFLICT of interests ,THROMBOCYTOPENIA ,NEWBORN infants - Abstract
This article presents a case study of a neonate with a rare vascular tumor called a rapidly involuting congenital hemangioma (RICH). The patient developed a condition called Kasabach-Merritt phenomenon, which caused severe thrombocytopenia and coagulopathy. The case highlights the challenges in managing such cases and suggests that tumor size may correlate with thrombocytopenia. The study emphasizes the importance of a multidisciplinary team in making treatment decisions and the potential complications of large RICHs. The research was supported by the Italian Ministry of Health and the authors have no conflicts of interest. [Extracted from the article]
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- 2023
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4. Epidydimo-orchitis and anorectal malformations: when and in whom?
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Zaccara, A., Ragozzino, S., Iacobelli, B. D., Rivosecchi, F., Capitanucci, M. L., Mosiello, G., Silveri, M., De Gennaro, M., and Bagolan, P.
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- 2015
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5. Peristeen® transanal irrigation in paediatric patients with anorectal malformations and spinal cord lesions: a multicentre Italian study
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Midrio, P., Mosiello, G., Ausili, E., Gamba, P., Marte, A., Lombardi, L., Iacobelli, B. D., Caponcelli, E., Marrello, S., Meroni, M., Brisighelli, G., Leva, E., and Rendeli, C.
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- 2016
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6. Isolated Fetal Ascites Secondary to Persistent Urogenital Sinus
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Camanni, D., Zaccara, A., Capitanucci, M. L., Mosiello, G., Capolupo, I., Iacobelli, B. D., and De Gennaro, M.
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Article Subject - Abstract
Objective. To present a case of isolated ascites secondary due to urogenital abnormalities (urogenital sinus) without any other prenatal ultrasound marker. Method. A 36-year-old woman with prenatal isolated ascites delivered a female baby, weighing 2.285 g; ascites was drained at birth and the baby underwent several episodes of urinary retention prior to undergoing X-ray investigations. Results. A voiding cystourethrogram revealed a short urogenital sinus: a vesicostomy was performed. A vaginoscopy revealed double vagina with a large posterior vagina. A posterior sagittal anorectal pull-through with genitoplasty was performed at 2 years old with 1-year follow-up. Conclusions. Though rare, a urogenital abnormality is to be suspected in fetal ascites cases with negative viral tests and no cardiac anomalies. The most common ultrasound marker of such abnormalities (fluid filled cavity) may be missing because of complete drainage of urine through the tubes into peritoneum.
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- 2009
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7. DOZ047.71: Long-gap vs. non-long-gap esophageal atresia: a prospective two-year follow-up study.
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Valfre, L, Conforti, A, Scuglia, M, Aite, L, Bevilacqua, F, Iacobelli, B D, Braguglia, A, and Bagolan, P
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ESOPHAGEAL atresia ,FUNDOPLICATION ,ESOPHAGEAL fistula ,ESOPHAGUS diseases ,CHILDREN'S hospitals - Published
- 2019
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8. Short versus mid-long-term outcome of transanal irrigation in children with spina bifida and anorectal malformations
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Ernesto Leva, E La Pergola, Antonio Marte, Milena Meroni, Laura Lombardi, Giovanni Mosiello, Claudia Rendeli, E. Ausili, Giulia Brisighelli, B.D. Iacobelli, Enrica Caponcelli, Paola Midrio, Ausili, E, Marte, A., Brisighelli, G., Midrio, P., Mosiello, G., La Pergola, E., Lombardi, L., Iacobelli, B. D., Caponcelli, E., Meroni, M, Leva, E., and Rendeli, C.
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Quality of life ,Male ,Pediatrics ,medicine.medical_specialty ,Constipation ,Adolescent ,Bowel management ,Transanal irrigation ,03 medical and health sciences ,0302 clinical medicine ,Neurogenic Bowel ,Anorectal malformation ,Fecal incontinence ,Spina bifida ,Anorectal Malformations ,Child ,Female ,Humans ,Quality of Life ,Spinal Dysraphism ,Therapeutic Irrigation ,Treatment Outcome ,medicine ,Adverse effect ,Constipation Fecal incontinence Anorectal malformation Spina bifida Transanal irrigation Quality of life ,business.industry ,General Medicine ,medicine.disease ,Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA ,030220 oncology & carcinogenesis ,Pediatrics, Perinatology and Child Health ,030211 gastroenterology & hepatology ,Neurology (clinical) ,medicine.symptom ,business - Abstract
Purpose We assessed short- and mid-long-term clinical efficacy of transanal irrigation (TAI) and its effect on the quality of life of children with spina bifida (SB) and anorectal malformations (ARM). Methods Seventy-four pediatric patients (age 6–17 years) with SB and ARM with neurogenic bowel dysfunction were enrolled for a prospective and multicentric study. Patients were evaluated before the beginning of TAI (T0), after 3 months (T1) and after at least 2 years (range 24–32 months) (T2) using a questionnaire assessing bowel function, the Bristol scale, and two validated questionnaires on quality of life: the CHQ-PF50 questionnaire for the parents of patients aged 6–11 years and the SF36 questionnaires for patients aged between 12 and 18 years. Results Seventy-two patients completed TAI program in T1, and 67 continued into T2. Bowel outcomes (constipation and fecal incontinence) improved in both the SB and the ARM groups in the short and mid-long term. In both groups at T1 and T2, parents and children reported an improvement in quality of life and there was a significant increase of stool form types 4 and 5 as described by the Bristol scale. Common adverse effects during the study were similar at T1 and T2 without serious complications. Conclusions We observed a sustained improvement in bowel management and quality of life in SB and ARM children during the study, more significant in the short term than in mid-long term. To maintain success rates in the mid-long term and to reduce the dropout rate, we propose patient training and careful follow-ups.
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- 2018
9. The impact of perioperative care on complications and short term outcome in ARM type rectovestibular fistula: An ARM-Net consortium study.
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van der Steeg HJJ, van Rooij IALM, Iacobelli BD, Sloots CEJ, Leva E, Broens P, Fascetti Leon F, Makedonsky I, Schmiedeke E, García Vázquez A, Midrio P, Lisi G, Amerstorfer E, Miserez M, Fanjul M, Ludwiczek J, Stenström P, Giuliani S, van der Steeg AFW, and de Blaauw I
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- Antibiotic Prophylaxis, Humans, Retrospective Studies, Anorectal Malformations surgery, Perioperative Care methods, Perioperative Care statistics & numerical data, Postoperative Complications epidemiology, Rectal Fistula surgery
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Background: The impact of perioperative care interventions on postreconstructive complications and short-term colorectal outcome in patients with anorectal malformation (ARM) type rectovestibular fistula is unknown., Methods: An ARM-Net consortium multicenter retrospective cohort study was performed including 165 patients with a rectovestibular fistula. Patient characteristics, perioperative care interventions, timing of reconstruction, postreconstructive complications and the colorectal outcome at one year of follow-up were registered., Results: Overall complications were seen in 26.8% of the patients, of which 41% were regarded major. Differences in presence of enterostomy, timing of reconstruction, mechanical bowel preparation, antibiotic prophylaxis and postoperative feeding regimen had no impact on the occurrence of overall complications. However, mechanical bowel preparation, antibiotic prophylaxis ≥48 h and postoperative nil by mouth showed a significant reduction in major complications. The lowest rate of major complications was found in the group having these three interventions combined (5.9%). Multivariate analyses did not show independent significant results of any of the perioperative care interventions owing to center-specific combinations. At one year follow-up, half of the patients experienced constipation and this was significantly higher among those with preoperative mechanical bowel preparation., Conclusions: Differences in perioperative care interventions do not seem to impact the incidence of overall complications in a large cohort of European rectovestibular fistula-patients. Mechanical bowel preparation, antibiotic prophylaxis ≥48 h, and postoperative nil by mouth showed the least major complications. Independency could not be established owing to center-specific combinations of interventions., Type of Study: Treatment study., Level of Evidence: III., (Copyright © 2019 Elsevier Inc. All rights reserved.)
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- 2019
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10. Pulmonary hypertension in neonates with high-risk congenital diaphragmatic hernia does not affect mid-term outcome.
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Valfre L, Braguglia A, Conforti A, Morini F, Trucchi A, Iacobelli BD, Nahom A, Capolupo I, Dotta A, and Bagolan P
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- Follow-Up Studies, Hernia, Diaphragmatic complications, Hernia, Diaphragmatic therapy, Humans, Infant, Newborn, Prospective Studies, Treatment Outcome, Hernias, Diaphragmatic, Congenital, Hypertension, Pulmonary complications
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Purpose: Congenital diaphragmatic hernia (CDH) presents with a broad spectrum of severity, depending on the degree of pulmonary hypoplasia and persistent pulmonary hypertension (PPH). It is currently not clear whether pulmonary hypertension may affect late morbidity. Aim of the present study was to evaluate the influence of PPH on mid-term morbidity in high-risk CDH survivors., Methods: All high-risk (prenatal diagnosis and/or respiratory symptoms within 6 h of life) CDH survivors, treated between 2004 and 2008 in our Department were followed up in a multidisciplinary outpatient clinic as part of a longitudinal prospective study. Auxological, gastroesophageal, pulmonary and orthopedic evaluations were done at specific time-points (at 6, 12, and 24 months of age). Patients were grouped depending on the presence/absence of pulmonary hypertension (defined by expert pediatric cardiologists after echocardiography). Paired t-test and Fisher's exact test were used as appropriate. P < 0.05 was considered significant., Results: 70 survivors out of a total of 95 high-risk CDH infants treated in our Department attended our follow-up clinic and were prospectively evaluated. 17 patients were excluded from the present study because no clear data was available regarding the presence/absence of PPH during the perinatal period. Moreover, 9 infants were not enrolled because they did not reach at least 6 months of age. A total of 44 survivors were finally enrolled since they met the inclusion criteria. 26 infants did not present with PPH during the first hospital admission, while 18 had PPH. The 2 groups did not differ with regard to any of the outcomes considered at follow-up (p > 0.2)., Conclusion: In our cohort of high-risk CDH survivors, PPH was not found to affect late sequelae at mid-term follow-up. This may indicate that postnatal pulmonary development is not (always) influenced by perinatal PPH. Nevertheless, a longer follow-up and more patients are needed to properly quantify possible late problems in high-risk CDH survivors with associated neonatal PPH., (© Georg Thieme Verlag KG Stuttgart · New York.)
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- 2011
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11. Cardiopulmonary performances in young children and adolescents born with large abdominal wall defects.
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Zaccara A, Iacobelli BD, Calzolari A, Turchetta A, Orazi C, Schingo P, and Bagolan P
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- Adolescent, Child, Exercise Test, Female, Follow-Up Studies, Gastroschisis rehabilitation, Hernia, Umbilical rehabilitation, Humans, Male, Oxygen Consumption, Physical Fitness, Retrospective Studies, Vital Capacity, Exercise Tolerance, Gastroschisis surgery, Heart physiopathology, Hernia, Umbilical surgery, Lung physiopathology
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Background/purpose: As long as the survival rate of patients with abdominal wall defects (AWD) increases, information about long-term follow-up is becoming necessary. Even though quality of life in these patients, in absence of associated anomalies, appears to be unaffected, respiratory impairment soon after birth has been documented; therefore, participation in sports rarely is addressed., Methods: Eighteen patients, ranging in age from 7 to 18 years, operated on at birth for large abdominal wall defects (> 4 cm for gastroschisis; >6 cm for omphalocele) were asked to come for a stress test on a treadmill, with measurements of time of exercise (TE), maximal oxygen consumption (VO2 max) and continuous recording of vital parameters. Respiratory function also was assessed by Forced Vital Capacity (FVC)., Results: Ergometric data were compared with those of a normal pediatric population. All patients were able to perform the stress test with no cardiovascular abnormalities detected at rest or on exertion. Maximum heart rate was reached after a significantly shorter TE, and VO2 max was significantly reduced when comparing normal subjects with AWD subjects and AWD subjects in sports with those sedentary. FVC was only slightly reduced in AWD patients without reaching statistical significance., Conclusions: These findings indicate that patients operated on for AWD at birth exhibit a normal cardiorespiratory function; decreased TE and VO2 max are likely to reflect a lack of physical activity with a lower degree of fitness. Therefore, no limitations to motor performances should exist for these patients. Well-being may be greatly improved by regular exercise., (Copyright 2003, Elsevier Science (USA). All rights reserved.)
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- 2003
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12. Role of electrogastrography in detecting motility disorders in children affected by chronic intestinal pseudo-obstruction and Crohn's disease.
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Bracci F, Iacobelli BD, Papadatou B, Ferretti F, Lucchetti MC, Cianchi D, Francalanci P, and Ponticelli A
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- Adolescent, Adult, Child, Child, Preschool, Chronic Disease, Female, Humans, Male, Postprandial Period physiology, Crohn Disease physiopathology, Electrodiagnosis, Gastrointestinal Motility, Intestinal Pseudo-Obstruction physiopathology
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Gastrointestinal motility disorders are frequently found in several pathologies. The aim of this study was to assess, by means of electrogastrography, the presence of gastrointestinal motility abnormalities in children affected by Crohn's disease (CD) or Chronic Intestinal Pseudo-Obstruction (CIPO). Patients and Methods. We studied 34 subjects; 20 control subjects (M = 15, mean age = 10 +/- 3.5 yrs), 8 patients (M = 4, mean age = 18 +/- 7 yrs) with Crohn's disease in a quiescent phase and 6 patients (M = 6, mean age = 10 +/- 3.5 yrs) with Chronic Intestinal Pseudo-Obstruction. Results. Analysis of gastric electrical activity (GEA) parameters demonstrated that in the control group physiological post-prandial changes are represented by an increase of 3 Cycles Per Minute (3 CPM) activity, Period Dominant Power (PDP) and Period Dominant Frequency (PDF) and by the reduction of bradygastria. Crohn patients showed an insignificant increase of 3 CPM and PDP; CIPO patients showed an abnormal variation of 3 CPM, PDP and post-prandial bradygastria. Moreover, CD patients showed a significant difference in post-prandial values of PDP compared to normal subjects. CIPO patients revealed a significant difference in the values of either preprandial PDF with tachygastria or the post-prandial value of 3 CPM, compared to normal subjects. Conclusions. EEG is a non-invasive method to study gut motility related to GEA alterations present in CIPO as well as in CD patients.
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- 2003
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13. Exteriorization-aspiration minilaparotomy for treatment of neonatal ovarian cysts.
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Ferro F, Iacobelli BD, Zaccara A, Spagnoli A, Trucchi A, and Bagolan P
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- Female, Gynecologic Surgical Procedures, Humans, Infant, Newborn, Length of Stay, Suction, Laparotomy methods, Ovarian Cysts surgery
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Introduction: Recent literature indicates that laparoscopic techniques are considered the most appropriate approach for management of neonatal ovarian cysts (NOC). However, laparoscopic equipment may be unavailable in most centers, has high costs, and demands a long learning curve, especially in newborns., Methods: A minilaparotomy with exteriorization-aspiration ("catch and suck") approach was used in 14 female newborns with antenatally diagnosed ovarian cysts. Average operating time was 25 minutes (range 15-45 min.). Postoperative course was uneventful in all cases; no intra- or postoperative complications were recorded. Length of stay was 48 hours in all patients., Conclusions: Minilaparotomy with cyst aspiration and subsequent removal may prove a reliable and safe technique in the treatment of NOC: operating time and length of stay are not significantly longer than laparoscopic approach, making this procedure a valid alternative.
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- 2002
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14. Percutaneous endoscopic cecostomy for antegrade colonic irrigation in fecally incontinent children.
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De Peppo F, Iacobelli BD, De Gennaro M, Colajacomo M, and Rivosecchi M
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- Adolescent, Child, Colon, Colonoscopy, Fecal Incontinence diagnosis, Female, Humans, Male, Therapeutic Irrigation methods, Cecostomy methods, Endoscopy, Fecal Incontinence drug therapy, Fecal Incontinence surgery, Polyethylene Glycols administration & dosage, Surface-Active Agents administration & dosage
- Abstract
The Malone surgical procedure for antegrade continence enema (ACE) greatly improves the quality of life of many patients with fecal incontinence but has several complications. This report describes a technique of percutaneous endoscopic cecostomy (PEC) which was applied in three children with fecal incontinence secondary to anorectal malformation or spina bifida. Using a pediatric fiberscope, a colonoscopy was done which reached the right colon. An intraoperative ultrasound examination confirmed the position of the cecum just below the layers of the abdominal wall. The cecostomy tube was then percutaneously inserted, imitating the steps of percutaneous endoscopic gastrostomy (PEG) using the pull technique. The preliminary results are very encouraging: there are no procedure-related complications in this small series; all the patients are able to carry out the antegrade enema by themselves; and complete control of defecation has been obtained.
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- 1999
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15. An experimental animal model of intestinal obstruction to simulate in utero therapy for jejunoileal atresia.
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Patricolo M, Noia G, Rossi L, Zangari A, Pomini F, Catesini C, Filippetti R, Galli T, Iacobelli BD, Capuano LG, Romano D, Mancuso S, and Rivosecchi M
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- Animals, Female, Ileum abnormalities, Ileum surgery, Intestinal Obstruction etiology, Jejunum abnormalities, Jejunum surgery, Ligation, Pregnancy, Sheep, Disease Models, Animal, Fetal Diseases surgery, Intestinal Obstruction surgery
- Abstract
Objective: To obtain 'intestinal atresia-like' conditions in the fetal lamb model to subsequently allow in utero surgical repair., Methods: Six time-dated pregnant sheep underwent general anesthesia at 75 days of gestation (term 145 +/- 5 days). After maternal laparotomy and hysterotomy, the fetal abdomen was opened. Once the jejunoileal intestinal loop was identified, the mesenteric vessels were isolated, ligated, and sectioned in 2 fetuses, and in the remaining 5 fetuses the bowel loop was ligated. Two further fetuses were used as controls and underwent sole laparotomy. Of the group of 7 fetuses 2 were reoperated at 100-105 days of gestational age and underwent intestinal recanalization. Eight fetuses were delivered at term by cesarean section and the remaining 1 by spontaneous delivery. One newborn underwent neonatal entero-enteric anastomosis., Results: 4 out of 6 fetuses survived, in utero intestinal or vascular ligation having provoked an 'intestinal atresia-like' picture. The animal operated at birth died. The 2 control fetuses and the 2 fetuses with in utero intestinal recanalization survived until term., Conclusion: The present study shows that in utero treatment of intestinal obstruction is possible in an experimental model.
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- 1998
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16. Colorectal dysfunction and faecal incontinence in children with spina bifida.
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Ponticelli A, Iacobelli BD, Silveri M, Broggi G, Rivosecchi M, and De Gennaro M
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- Adolescent, Adult, Child, Colonic Diseases rehabilitation, Constipation etiology, Fecal Incontinence rehabilitation, Humans, Spinal Dysraphism rehabilitation, Treatment Outcome, Biofeedback, Psychology, Colonic Diseases etiology, Fecal Incontinence etiology, Spinal Dysraphism complications
- Abstract
Objectives: To quantify colorectal neurogenic dysfunction in children with spina bifida and to evaluate the clinical efficacy of appropriate rehabilitation performed by the coloproctologist in the spina bifida team., Patients and Methods: The bowel function of 73 patients with congenital (67) and acquired (six) spinal lesions (age 7-25 years) was evaluated by one physician. Evacuation habit was classified as full bowel control, mild and severe constipation or incontinence. Fifty-two children had mild or severe incontinence or constipation, 22 of whom were treated by the coloproctologist using biofeedback or conventional therapy; 30 were not treated. The outcome was compared between the groups, Results: Bowel constipation remained stable in 90% and was complicated in 10% of the untreated patients, while it ameliorated in 59% of patients who received specialist treatment., Conclusion: Neurogenic bowel dysfunction needs specialist management to achieve better results, using the concept of controlled incontinence. There was no significant difference between conventional therapy and biofeedback methods.
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- 1998
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17. Long-term urological follow-up of occult spinal dysraphism in children.
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Capitanucci ML, Iacobelli BD, Silveri M, Mosiello G, and De Gennaro M
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- Adolescent, Adult, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Infant, Male, Patient Care Team, Spina Bifida Occulta physiopathology, Urinary Bladder, Neurogenic physiopathology, Urinary Incontinence diagnosis, Urinary Incontinence physiopathology, Urinary Tract Infections diagnosis, Urinary Tract Infections physiopathology, Urodynamics physiology, Vesico-Ureteral Reflux diagnosis, Vesico-Ureteral Reflux physiopathology, Spina Bifida Occulta diagnosis, Urinary Bladder, Neurogenic diagnosis
- Abstract
From 1980 to 1996 we followed up 65 children with occult spinal dysraphism (OSD) out of 85 observed in our urodynamic laboratory. The average age at diagnosis was 4.7 years (range: 1-21 years). In 19 cases (22%) the OSD was associated with anorectal anomalies (ARA). Urinary incontinence or voiding anomalies with urinary tract infection were the presenting symptom in 34 children (49%). At diagnosis all children underwent complete neuro-urological and urodynamic evaluation. Thirty-eight patients underwent neurosurgical correction. Vesicoureteral reflux (VUR) was present or developed in 17 patients: 15 underwent endoscopic procedures and 2 required surgery; 2 needed bladder augmentation because of upper tract and renal function deterioration. Urinary incontinence was treated mainly by intermittent catheterization and anticholinergic drugs, but endoscopic treatment was performed in 3 children. At long-term follow-up (2 to 14 years), socially acceptable continence was achieved in 78% of 57 children (8 could not be assessed because they were less than 4 years old). Upper urinary tract deterioration occurred in 15% and renal failure in 7.5%.
- Published
- 1996
- Full Text
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