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1,646 results on '"IIzuka T"'

1. Frequency of coronary artery stenosis in patients with asymptomatic familial hypercholesterolemia and its association with carotid intimal thickness and cardio-ankle vascular index

Author

Suzuki M, Takahashi M, Iizuka T, Terada H, Noike H, and Shirai K

Subjects
CAVI, coronary artery stenosis, heterozygous familial hypercholesterolemia, CCTA, ultrasound evaluation of the carotid artery, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Masayo Suzuki,1 Mao Takahashi,1 Takuo Iizuka,1 Hitoshi Terada,2 Hirohumi Noike,1 Kohji Shirai3 1Cardiovascular Center, Internal Medicine, 2Department of Radiology, 3Department of Vascular Function, Sakura Hospital, Medical Center, Toho University, Sakura City, Chiba Prefecture, Japan Background: Familial hypercholesterolemia (FH) is associated with premature coronary arterial disease. We aimed to determine the incidence of coronary artery stenosis (CAS) in asymptomatic FH patients using coronary computed tomography angiography (CCTA). To investigate the association between CAS and atherosclerosis of carotid arteries, we performed ultrasonography to measure the mean intima-media thickness (IMT), maximum IMT, and plaque score. We also aimed to examine the significance of the cardio-ankle vascular index (CAVI) and its association with the incidence of CAS in asymptomatic FH patients. Patients and methods: We enrolled consecutively, 31 FH patients without symptoms of coronary artery disease. Based on the CCTA findings, we divided the patients into two groups, those with and without CAS, and compared various parameters and risk factors of the two groups. Results: Of 31 FH patients, seven patients (22.6%) had CAS. The proportion of male patients and mean low-density lipoprotein-cholesterol level were higher in patients with CAS than in those without CAS (P22.6% of the asymptomatic FH patients. Patients with CAS tended to have enhanced levels of carotid plaque markers, but no increase was noted in CAVI. FH patients should be continuously monitored using CCTA and ultrasonography. Keywords: CAVI, coronary artery stenosis, heterozygous familial hypercholesterolemia, CCTA, ultrasound evaluation of the carotid artery

Published
2016

2. Frequency of coronary artery stenosis in patients with asymptomatic familial hypercholesterolemia and its association with carotid intimal thickness and cardio-ankle vascular index [Corrigendum]

Author

Suzuki M, Takahashi M, Iizuka T, Terada H, Noike H, and Shirai K

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Suzuki M, Takahashi M, Iizuka T et al. Frequency of coronary artery stenosis in patients with asymptomatic familial hypercholesterolemia and its association with carotid intimal thickness and cardio-ankle vascular index. Research Reports in Clinical Cardiology. 2016;7:83–90. Read the original article

Published
2017

10. Hard x-ray photoemission spectroscopy of rhenium substituted higher manganese silicides.

Author

Matsunami, M., Iizuka, T., Ghodke, S., Yamamoto, A., Miyazaki, H., and Takeuchi, T.

Subjects
*PHOTOELECTRON spectroscopy, *HARD X-rays, *X-ray spectroscopy, *MANGANESE, *FERMI energy, *PHOTOEMISSION, *ELECTRONIC structure
Abstract

We have investigated the electronic structure of a potential thermoelectric material, higher manganese silicide, and its solid solutions with supersaturated Re by means of hard x-ray photoemission spectroscopy. The unusual Re substitution dependence of thermoelectric properties in the higher manganese silicide, reducing the electrical resistivity without altering the Seebeck coefficient, can be explained in terms of the variation of the density of states at the Fermi level and its energy derivative. Such an electronic structure variation contributes to an improvement in the thermoelectric performance in combination with the suppressed thermal conductivity. [ABSTRACT FROM AUTHOR]

Published
2020
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11. Gibberellin-regulated proteins: Emergent allergens

Author

Iizuka, T., Barre, A., Rougé, P., Charpin, D., Scala, E., Baudin, B., Aizawa, T., Sénéchal, H., Poncet, Pascal, Hokkaido University [Sapporo, Japan], Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Association pour la Prévention de la Pollution Atmosphérique (APPA), Istituto dermopatico dell'immacolata (IDI-IRCCS), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Département d'Immunologie - Department of Immunology, and Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité)

Subjects
food allergy, [SDV]Life Sciences [q-bio], pollen allergy, pollen food allergy syndrome, 3D structure, gibberellin-regulated protein, gibberellin-regulated protein pollen food allergy syndrome food allergy pollen allergy 3D structure
Abstract

International audience; About 10 years ago, a protein family was shown for the first time to contain allergenic members, gibberellin-regulated protein (GRP). The first reported member was from peach, Pru p 7. One can hypothesize that it was not detected before because its physicochemical characteristics overlap with those of lipid transfer protein (LTP), a well-known allergen, or because the exposure to GRP increased due to an increase in the gibberellin phythormone level in plant food, either exogenous or endogenous. Like LTPs, GRPs are small cationic proteins with disulfide bridges, are resistant to heat and proteolytic cleavage, and are involved in the defense of the plant. Besides peach, GRP allergens have been described in Japanese apricot (Pru m 7), sweet cherry (Pru av 7), orange (Cit s 7), pomegranate (Pun g 7), bell pepper (Cap a 7), strawberry (Fra a GRP), and also in pollen with a restriction to Cupressaceae tree family (Cup s 7, Cry j 7, and Jun a 7). IgE cross-reactivities were described between GRPs, and the reported peach/cypress and citrus/cypress syndromes may therefore be explained because of these GRP cross-reactivities. GRPs are clinically relevant, and severe adverse reactions may sometimes occur in association with cofactors. More than 60% and up to 95% sequence identities are calculated between various allergenic GRPs, and three-dimensional models show a cleft in the molecule and predict at least three epitopic regions. The structure of the protein and its properties and the matrix effect in the original allergenic source should be unraveled to understand why, despite the ubiquity of the protein family in plants, only a few members are able to sensitize patients.

Published
2022
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14. Chemical and isotopic characterization of Asteroid Ryugu

Author

Yokoyama, T., Nagashima, K., Nakai, I., Young, E., Abe, Y., Aléon, J., Alexander, C., Amari, S., Amelin, Y., Bajo, K., Bizzarro, M., Bouvier, A., Carlson, R., Chaussidon, M., Choi, B., Dauphas, N., Davis, A., Rocco, T., Fujiya, W., Fukai, R., Gautam, I., Haba, M., Hibiya, Y., Hidaka, H., Homma, H., Hoppe, P., Huss, G., Ichida, K., Iizuka, T., Ireland, T., Ishikawa, A., Ito, M., Itoh, S., Kawasaki, N., Kita, N., Kitajima, K., Kleine, T., Komatani, S., Krot, A., Liu, M., Masuda, Y., McKeegan, K., Morita, M., Motomura, K., Moynier, F., Nguyen, A., Nittler, L., Onose, M., Pack, A., Park, C., Piani, L., Qin, L., Russell, S., Sakamoto, N., Schönbächler, M., Tafla, L., Tang, H., Terada, K., Terada, Y., Usui, T., Wada, S., Wadhwa, M., Walker, R., Yamashita, K., Yin, Q., Yoneda, S., Yui, H., Zhang, A., Yurimoto, H., Tachibana, S., Nakamura, T., Naraoka, H., Noguchi, T., Okazaki, R., Sakamoto, K., Yabuta, H., Tsuda, Y., and Watanabe., S.

Published
2022

15. In-situ Oxygen and Manganese-Chromium Isotope studies of Ryugu: Implications to temperature and timing of aqueous activity

Author

Nagashima, K., Kawasaki, N., Sakamoto, N., Yokoyama, H., Yurimoto, T., Nakai, I., Young, E., Abe, Y., Aléon, J., Alexander, C., Amari, S., Amelin, Y., Bajo, K., Bizzarro, M., Bouvier, A., Carlson, R., Chaussidon, M., Choi, B., Dauphas, N., Davis, A., Rocco, T., Fujiya, W., Fukai, R., Gautam, I., Haba, M., Hibiya, Y., Hidaka, H., Homma, H., Hoppe, P., Huss, G., Ichida, K., Iizuka, T., Ireland, T., Ishikawa, A., Ito, M., Itoh, S., Kita, N., Kitajima, K., Kleine, T., Komatani, S., Krot, A., Liu, M., Masuda, Y., McKeegan, K., Morita, M., Motomura, K., Moynier, F., Nguyen, A., Nittler, L., Onose, M., Pack, A., Park, C., Piani, L., Qin, L., Russell, S., Schönbächler, M., Tafla, L., Tang, H., Terada, K., Terada, Y., Usui, T., Wada, S., Wadhwa, M., Walker, R., Yamashita, K., Yin, Q., Yoneda, S., Yui, H., Zhang, A., and Yurimoto, H.

Published
2022

16. The Oxygen Isotopic Composition of Samples returned from, Asteroid Ryugu: Evidence for similarity to CI Chondrites

Author

Young, E., Tang, H., Tafla, L., Pack, A., Rocco, T., Yokoyama, T., Nagashima, K., Nakai, I., Abe, Y., ́Aleon, J., Alexander, C., Amari, S., Amelin, Y., Bajo, K., Bizzarro, M., Bouvier, A., Carlson, R., Chaussidon, M., Choi, B., Dauphas, N., Davis, A., Fujiya, W., Fukai, R., Gautam, I., Haba, M., Hibiya, Y., Hidaka, H., Homma, H., Hoppe, P., Huss, G., Ichida, K., Iizuka, T., Ireland, T., Ishikawa, A., Ito, M., Itoh, S., Kawasaki, N., Kita, N., Kitajima, K., Kleine, T., Komatani, S., Krot, A., Liu, M., Masuda, Y., McKeegan, K., Morita, M., Motomura, K., Moynier, F., Nguyen, A., Nittler, L., Onose, M., Park, C., Piani, L., Qin, L., Russell, S., Sakamoto, N., Schönbächler, M., Terada, K., Terada, Y., Usui, T., Wada, S., Wadhwa, M., Walker, R., Yamashita, K., Yin, Q., Yoneda, S., Yui, H., Zhang, A., Yurimoto, H., Tachibana, S., Nakamura, T., Naraoka, H., Noguchi, T., Okazaki, R., Sakamoto, K., Yabuta, H., Tsuda, Y., and Watanabe, S.

Published
2022

17. Multi-Isotopic Analyses of Bulk Ryugu Samples returned by the Hayabusa2 Mission

Author

Yokoyama, T., Nagashima, K., Nakai, I., Young, E., Abe, Y., Aléon, J., Alexander, C., Amari, S., Amelin, Y., Bajo, K., Bizzarro, M., Bouvier, A., Carlson, R., Chaussidon, M., Choi, B., Dauphas, N., Davis, A., Rocco, T., Fujiya, W., Fukai, R., Gautam, I., Haba, M., Hibiya, Y., Hidaka, H., Homma, H., Hoppe, P., Huss, G., Ichida, K., Iizuka, T., Ireland, T., Ishikawa, A., Ito, M., Itoh, S., Kawasaki, N., Kita, N., Kitajima, K., Kleine, T., Komatani, S., Krot, A., Liu, M., Masuda, Y., McKeegan, K., Morita, M., Motomura, K., Moynier, F., Nguyen, A., Nittler, L., Onose, M., Pack, A., Park, C., Piani, L., Qin, L., Russell, S., Sakamoto, N., Schönbächler, M., Tafla, L., Tang, H., Terada, K., Terada, Y., Usui, T., Wada, S., Wadhwa, M., Walker, R., Yamashita, K., Yin, Q., Yoneda, S., Yui, H., Zhang, A., Tachibana, H., Nakamura, T., Naraoka, H., Noguchi, T., Okazaki, R., Sakamoto, K., Yabuta, H., Yurimoto, H., Tsuda, Y., and Watanabe, S.

Published
2022

18. Sampling Mass and Chemical Heterogeneities Among Ryugu Samples Returned by the Hayabusa2 Mission

Author

Dauphas, N., Yokoyama, T., Nagashima, K., Nakai, I., Young, E., Abe, Y., Aléon, J., Alexander, C., Amari, S., Amelin, Y., Bajo, K., Bizzarro, M., Bouvier, A., Carlson, R., Chaussidon, M., Choi, B., Davis, A., Rocco, T., Fujiya, W., Fukai, R., Gautam, I., Haba, M., Hibiya, Y., Hidaka, H., Homma, H., Hoppe, P., Huss, G., Ichida, K., Iizuka, T., Ireland, T., Ishikawa, A., Ito, M., Itoh, S., Kawasaki, N., Kita, N., Kitajima, K., Kleine, T., Komatani, S., Krot, A., Liu, M., Masuda, Y., McKeegan, K., Morita, M., Motomura, K., Moynier, F., Nguyen, A., Nittler, L., Onose, M., Pack, A., Park, C., Piani, L., Qin, L., Russell, S., Sakamoto, N., Schönbächler, M., Tafla, L., Tang, H., Terada, K., Terada, Y., Usui, T., Wada, S., Wadhwa, M., Walker, R., Yamashita, K., Yin, Q., Yoneda, S., Yui, H., Zhang, A., Yurimoto, H., Tachibana, S., Nakamura, T., Naraoka, H., Noguchi, T., Okazaki, R., Sakamoto, K., Yabuta, H., Tsuda, Y., and Watanabe, S.

Published
2022

31. Vasorelaxant effects of forsythide isolated from the leaves of forsythia viridissima on NE-induced aortal contraction

Author

Iizuka, T., Sakai, H., Moriyama, H., Suto, N., Nagai, M., and Bagchi, D.

Subjects
Vasoconstriction -- Care and treatment -- Research, Phytochemicals -- Health aspects -- Research, Biological sciences, Health, Science and technology, Care and treatment, Research, Health aspects
Abstract

Abstract Forsythide (F1) isolated from the leaves of Forsythia viridissima (Oleaceae) showed vasorelaxant effects on norepinephrine (NE)-induced contraction of rat aorta with or without endothelium. This compound did not affect [...]

Published
2009
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