1,159 results on '"Hengstler, Jan G."'
Search Results
2. Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
3. Role of albumin in the metabolism and excretion of ochratoxin A
4. Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats
5. Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats
6. Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
7. EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis
8. Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
9. Basic concepts of mixture toxicity and relevance for risk evaluation and regulation
10. PFASs–restriction proposal commentary on ECHA’s Annex XV restriction report, proposal for a restriction, March 2023
11. Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS
12. Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
13. The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects
14. Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease
15. Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells
16. Alterations in the hepatocyte epigenetic landscape in steatosis
17. Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth
18. Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences
19. G × E interactions as a basis for toxicological uncertainty
20. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat
21. The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults
22. Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis
23. Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease
24. Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
25. Classification of hepatotoxicity of compounds based on cytotoxicity assays is improved by additional interpretable summaries of high-dimensional gene expression data
26. Risk assessment of parabens in a transcriptomics-based in vitro test
27. Ricin: an ancient toxicant, but still an evergreen
28. Sublethal necroptosis signaling promotes inflammation and liver cancer
29. Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights
30. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A
31. Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins
32. Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity
33. Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes
34. Chronic stress is associated with specific path integration deficits
35. Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value)
36. Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy
37. Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis
38. Recent research on Novichok
39. Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells
40. In memoriam Thomas Gebel
41. Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer
42. In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay
43. td2pLL: An intuitive time-dose-response model for cytotoxicity data with varying exposure durations
44. Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue
45. Correction: In memoriam Thomas Gebel
46. Enigmatic mechanism of the N-vinylpyrrolidone hepatocarcinogenicity in the rat
47. Identification of Ppar γ -modulated miRNA hubs that target the fibrotic tumor microenvironment
48. The EU chemicals strategy for sustainability: in support of the BfR position
49. Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
50. Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study
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