77 results on '"Hajdůch, Marián"'
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2. “Keep on ROCKIn”: Repurposed ROCK inhibitors to boost corneal endothelial regeneration
3. Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action
4. Nucleoside-based anticancer drugs: Mechanism of action and drug resistance
5. Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone)
6. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition
7. Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
8. Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
9. Activity of 1-aryl-4-(naphthalimidoalkyl) piperazine derivatives against Leishmania major and Leishmania mexicana
10. Characterization of drug effects on cell cultures from phase-contrast microscopy images
11. Missense mutation in RPS7 causes Diamond-Blackfan anemia via alteration of erythrocyte metabolism, protein translation and induction of ribosomal stress
12. Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters
13. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX
14. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors
15. Czech and Slovak Diamond-Blackfan Anemia (DBA) Registry update: Clinical data and novel causative genetic lesions
16. Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics
17. Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid
18. Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold
19. Prevalence of human papillomavirus infection in oocyte donors and women treated for infertility: An observational laboratory-based study
20. Integrated physical map of bread wheat chromosome arm 7DS to facilitate gene cloning and comparative studies
21. Genetic Markers in Triple-Negative Breast Cancer
22. Label-free determination and multiplex analysis of DNA and RNA in tumor tissues
23. Cardiac amyloidosis: from clinical suspicion to morphological diagnosis
24. Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids
25. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells
26. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the “classical” cytokinin ribosides
27. Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells
28. Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation
29. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides
30. Analysis of Prognostic Significance of Merkel Cell Polyomavirus in Chronic Lymphocytic Leukemia
31. Pathophysiologically relevant in vitro tumor models for drug screening
32. Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells
33. Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton
34. Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs
35. Time- and dose-dependent seeding tendency of exogenous tau R2 and R3 aggregates in cells
36. Synthesis and cytotoxicity of some d-mannose click conjugates with aminobenzoic acid derivatives
37. Synthetic Cyclin Dependent Kinase Inhibitors : New Generation of Potent Anti-Cancer Drugs
38. Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid
39. Synthesis of various 5-alkoxymethyluracil analogues and structure–cytotoxic activity relationship study
40. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage.
41. Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity
42. Anticancer activity of natural cytokinins: A structure–activity relationship study
43. Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation
44. Cyclocondensation reaction of heterocyclic carbonyl compounds, Part XIII: Synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3- e][1,2,4]triazines
45. Biomarkers of Aspergillus spores: Strain typing and protein identification
46. Challenges in cancer research and multifaceted approaches for cancer biomarker quest
47. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2 H)-one Derivatives.
48. Assessing different thiazolidine and thiazole based compounds as antileishmanial scaffolds
49. Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5- a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines
50. Synthesis and cytotoxic activity of substituted 2-phenyl-3-hydroxy-4(1 H)-quinolinones-7-carboxylic acids and their phenacyl esters
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