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This research implements the whale optimization algorithm (WOA) and spotted hyena optimizer (SHO) in inverse scattering to regenerate the conductor shape concealed in the half-space. TM waves are irradiated from the other half-space to a perfect conductor with an unknown shape buried in one half-space. The scattered field measured outside the conductor surface with the boundary condition is used to reconstruct the object using the WOA and SHO algorithms. Several scenarios of reconstruction accuracy were compared for the WOA and SHO. The numerical simulations prove that the WOA has a better reconstruction capability.

Electromagnetic imaging is an emerging technology widely applied in many fields, such as medical imaging, biomedical imaging, and nondestructive testing. In this study, we place transmitter and receiver antennas around an unknown object. We can use the direct sampling method (DSM) to reconstruct the material size and shape of the unknown object on the basis of the scattered field. We apply U-Net to reconstruct electromagnetic images of perfect conductors. Perfect conductors in free space are studied by irradiating a transverse magnetic (TM) polarization wave. Using the scattered electric field measured outside the object together with the boundary conditions on the conductor surface, a set of nonlinear integral equations can be derived and further converted into matrix form by the method of moments. Since an iterative algorithm is computationally expensive and time-consuming, a real-time electromagnetic imaging technique combining deep learning neural networks is proposed for reconstructing the perfect conductors. The initial shapes of the conductors are first computed by DSM by using the scattered electric field measured outside the object. The initial shapes of the conductors are then input to U-Net for training. Numerical results show that U-Net is capable of reconstructing accurate conductor shapes. Therefore, artificial intelligence techniques can reconstruct shapes more accurately than iterative algorithms, when combined with DSM. [ABSTRACT FROM AUTHOR]

Several theories on the origin of adenomyosis (ADS) have been proposed, of which the most widely accepted is the fundamental pathogenic role of uterine eutopic endometrium. Emerging evidence suggests that circular RNAs participate in the multiple tumorgenesis. The vital importance of circular RNA PVT1 (circPVT1) in the pathological progress like malignancies has been well documented. Nevertheless, its underlying correlation with ADS remains elusive yet. The purpose of this study was to investigate the expression pattern, regulatory effect, and internal mechanism of circPVT1 in ADS. qRT-PCR was performed to detect the relative mRNA expression of circPVT1, miR-145, and Talin1 in ADS endometrial tissue and cells. The protein level of Talin1 was measured by Western blot and immunochemistry. Immunofluorescence was used to identify the primary endometrial epithelial and stromal cells. circPVT1 knockdown in vitro was achieved by transfecting with specific lentivirus vector CCK-8, and colony formation assays were utilized to assess cell proliferation; meanwhile, the transwell assay was employed for evaluating cell invasion ability. By conducting bioinformatics, dual-luciferase reporter assay, or RNA immunoprecipitation (RIP) experiment, the interaction between miR-145 and circPVT1 or Talin1 was verified. Rescue experiments further determined the regulatory effect of circPVT1/miR-145/Talin1 axis. We found both circPVT1 and Talin1 were markedly upregulated in ADS endometrial tissue and cells, whereas miR-145 was decreased. Elevated expression of circPVT1 was closely related to the severity of dysmenorrhea, menorrhagia, and uterine enlargement of patients with ADS. Knockdown of circPVT1 inhibited adenomyotic epithelial and stromal cell proliferation and invasion. Further mechanistic experiments revealed that circPVT1 negatively regulated miR-145 through serving as a molecular sponge. And the facilitating effect of circPVT1 was partially reversed by miR-145. Talin1 was demonstrated to be a down target of miR-145 and indirectly affected by circPVT1. Our findings unveiled that enhanced circPVT1 may be involved in the pathogenesis of ADS via stimulating endometrial cell proliferation and invasion. The establishment of circPVT1/miR-145/Talin1 pathway might present a novel therapeutic insight for ADS. [ABSTRACT FROM AUTHOR]