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256 results on '"Goncharova O"'

1. CORRELATION BETWEEN CHRONIC SYSTEMIC INFLAMMATION, LIPID SPECTRUM, LIVER FUNCTION AND ANTIOXIDANT SYSTEM IN PATIENTS WITH COMORBID PATHOLOGY OF STABLE CORONARY HEART DISEASE WITH NONALCOHOLIC FATTY LIVER DISEASE

Author

Manusha Yu. I., Goncharova O. O., Sakevich V. D., Chekalina N. I., and Kazakov Yu. M.

Subjects
ischemic heart disease, nonalcoholic fatty liver disease, chronic systemic inflammation, dislipidemia, endothelial dysfunction, correlation., Medicine, Biology (General), QH301-705.5
Abstract

The aim of the study was to examine the correlations between markers of chronic systemic inflammation (CHD), inflammatory endothelial activation, blood lipid spectrum, antioxidant system, liver and heart function in patients with stable coronary heart disease in combination with non-alcoholic fatty liver disease. The study involved 110 people with coronary heart disease: stable angina pectoris, II FC, CH 0-I in combination with non-alcoholic fatty liver disease aged 40-69 years. The analysis of indicators of a lipid spectrum of blood is made, studied the level of ceruloplasmin, cytokines (IL-6, TNFα, IL-10), circulating endothelial microparticles (CEM) CD32+ CD40+ in the blood, the expression of kappa B inhibitor mRNA gene α (IkBα) of nuclear kappa B transcription factor in peripheral blood mononuclear cells was studied and echocardiography, liver ultrasound with color and pulse Doppler imaging were performed (blood flow velocity in portal and hepatic veins was established). The relationship between the variables was then studied by correlation analysis. Conclusion. The correlation analysis established the relationship between the expression of mRNA IkBα nuclear transcription factor Kappa B with chronic systemic inflammation of low intensity, lipid metabolism with dysfunctional changes in blood flow in the liver (blood flow velocity in the portal vein), we can conclude that chronic systemic inflammation at the molecular genetic level plays an important role in the development of both coronary heart disease and nonalcoholic fatty liver disease and confirms the common pathogenetic mechanism of this comorbid pathology.

Published
2020
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2. A Pilot National Network for Monitoring Soil Respiration in Russia: First Results and Prospects of Development

Author

Kurganova, I. N., Karelin, D. V., Kotlyakov, V. M., Prokushkin, A. S., Zamolodchikov, D. G., Ivanov, A. V., Ilyasov, D. V., Khoroshaev, D. A., de Gerenyu, V. O. Lopes, Bobrik, A. A., Bryanin, S. V., Goncharova, O. Yu., Ershov, V. V., Ivanov, D. G., Zorina, S. Yu., Kaganov, V. V., Kapitsa, E. A., Koptsik, G. N., Kuznetsov, M. A., Kumanyaev, A. S., Kuprin, A. V., Mamai, A. V., Matvienko, A. I., Makhnykina, A. V., Mostovaya, A. S., Moshkina, E. V., Mothenov, S. Yu., Ryabov, N. S., Sapronov, D. V., Sidenko, N. V., Sokolova, L. G., Sorokin, A. S., Suvorov, G. G., Sukhoveeva, O. E., Chumbaev, A. S., and Shmakova, N. Yu.

Published
2024
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19. Numerical Simulation of Thermocapillary Convection with Evaporation Induced by Boundary Heating.

Author

Goncharova, O. N. and Bekezhanova, V. B.

Subjects
BOUSSINESQ equations, BILAYER lipid membranes, PLASMA boundary layers, EVAPORATIVE power, CONVECTIVE flow
Abstract

The dynamics of a bilayer system filling a rectangular cuvette subjected to external heating is studied. The influence of two types of thermal exposure on the flow pattern and on the dynamic contact angle is analyzed. In particular, the cases of local heating from below and distributed thermal load from the lateral walls are considered. The simulation is carried out within the frame of a two-sided evaporative convection model based on the Boussinesq approximation. A benzine–air system is considered as reference system. The variation in time of the contact angle is described for both heating modes. Under lateral heating, near-wall boundary layers emerge together with strong convection, whereas the local thermal load from the lower wall results in the formation of multicellular motion in the entire volume of the fluids and the appearance of transition regimes followed by a steady-state mode. The results of the present study can aid the design of equipment for thermal coating or drying and the development of methods for the formation of patterns with required structure and morphology. [ABSTRACT FROM AUTHOR]

Published
2024
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45. Anthropological Aesthetics of Greek Antiquity as a Narrative of Philosophical Discourse

Author

Goncharova, O. M.

Subjects
anthropological aesthetics of antiquity, cultural body, epistemological subject, social body, natural body
Abstract

Purpose.The article aims to define the philosophical narratives about the "beautiful human" of Greek antiquity in the coordinates of the triad of "natural", "social" and "cultural" body.Theoretical basis.When achieving this purpose, the author based on the conceptual provisions of the philosophical anthropology of Н. Plessner, in particular, concerning the attitude of a limited body to its limit as an empirical comprehension of a human him/herself and the world. Developing the position of the body as a socio-cultural phenomenon and proceeding from the definition of corporeality as a "transformed human body under the influence of social and cultural factors, which has socio-cultural meanings and performs certain socio-cultural functions" (I. Bykhovskaya) (transl. by O. G.), the triad of "natural", "social" and "cultural" body was used as a methodological basis to analyse the research object.Originalitylies in the explication of the peculiarities of aesthetic and anthropological discourse in Ancient Greek philosophy, not only through the prism of the dichotomy of "soul" and "body", but also through the prism of the triad "natural", "social" and "cultural" body, allowing rethinking of the narratives concerning the "beautiful human" of the formation period of the European anthropological aesthetics in Antiquity.Conclusions.The anthropological aesthetics of Greek Antiquity is masculine aesthetics, the aesthetics of the male "cultural body". If a man is an epistemological subject, he is able, despite the ugliness and abomination of his natural body, to reach the level of the cultural body, the level of "personal existence of corporeality". As for the female corporeality, since the Ancient Greek philosophy does not provide the status of an epistemological subject for a woman, she remains at the level of "social body".

Published
2022

49. Influence of Moisture on the CO2 Flux from Palsa Mire Soils in the North of Western Siberia.

Author

Matyshak, G. V., Chuvanov, S. V., Goncharova, O. Yu., Trifonova, V. A., Timofeeva, M. V., Isaeva, A. V., and Tarkhov, M. O.

Subjects
PEAT soils, HYDROMORPHIC soils, BOGS, SOILS, PEAT bogs, SOIL moisture
Abstract

The influence of the moisture content on the CO2 emission from peat soils of palsa mires in the discontinuous permafrost area was studied in the north of Western Siberia (Nadym region). The СО2 flux was measured in Histic Cryosols of permafrost peatlands (palsas) and Fibric Histosols of surrounding bog using the closed chamber method for four years at the peak of the growing season (August). Despite a significant difference in the soil moisture (34.8 ± 13.2 and 56.2 ± 2.1% on average), no significant difference in the CO2 emission from these ecosystems was found in any of the observation years; the rates of emission averaged 199.1 ± 90.1 and 182.1 ± 85.1 mg CO2 m–2 × h–1, respectively. Experimental wetting or drying (with a twofold difference in the moisture content) of peat soils at the two sites via their transplantation to a different position showed no significant effect on the CO2 emission even three years after the beginning of the experiment. The absence of significant differences in the CO2 flux between the two different ecosystems was explained by the presence of permafrost and the influence of many multidirectional factors mitigating changes in the CO2 production by soils. An increased CO2 emission from the peat soils of bogs was possible due to the additional contribution of the methanotrophic barrier and the lateral runoff of dissolved CO2 over the permafrost table from the palsa toward the surrounding bog. The absence of response of the CO2 emission to a significant change in the soil moisture content may be indicative of a wide optimum of this characteristic for the microbiological activity of peat soils in the studied region. The obtained data suggest that, while studying CO2 fluxes in cryogenic soils of hydromorphic landscapes, it is necessary to take into account not only biogenic sources, but also other factors, often of a physical nature, affecting the balance of CO2 fluxes and CO2 emission from soils. [ABSTRACT FROM AUTHOR]

Published
2023
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