294 results on '"Gheysens O"'
Search Results
2. Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors
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Lopci, E., Aide, N., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W. A., Van den Abbeele, A. D., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Hicks, R. J.
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- 2022
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3. Diagnostic value of [18F]FDG-PET/CT for treatment monitoring in large vessel vasculitis: a systematic review and meta-analysis
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van der Geest, K. S. M., Treglia, G., Glaudemans, A. W. J. M., Brouwer, E., Sandovici, M., Jamar, F., Gheysens, O., and Slart, R. H. J. A.
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- 2021
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4. Diagnostic value of [18F]FDG-PET/CT in polymyalgia rheumatica: a systematic review and meta-analysis
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van der Geest, K. S. M., Treglia, G., Glaudemans, A. W. J. M., Brouwer, E., Jamar, F., Slart, R. H. J. A., and Gheysens, O.
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- 2021
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5. Analysis of partial volume correction on quantification and regional heterogeneity in cardiac PET
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Turco, A., Nuyts, J., Duchenne, J., Gheysens, O., Voigt, J.U., Claus, P., and Vunckx, K.
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- 2020
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6. The value of 18F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis
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ten Hove, D., Treglia, G., Slart, R. H. J. A., Damman, K., Wouthuyzen-Bakker, M., Postma, D. F., Gheysens, O., Borra, R. J. H., Mecozzi, G., van Geel, P. P., Sinha, B., and Glaudemans, A. W. J. M.
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- 2021
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7. Prognostic superiority of International Prognostic Index over [18F]FDG PET/CT volumetric parameters in post-transplant lymphoproliferative disorder
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Montes de Jesus, F., Dierickx, D., Vergote, V., Noordzij, W., Dierckx, R. A. J. O., Deroose, C. M., Glaudemans, A. W. J. M., Gheysens, O., and Kwee, T. C.
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- 2021
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8. Partial volume and motion correction in cardiac PET: First results from an in vs ex vivo comparison using animal datasets
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Turco, A., Gheysens, O., Duchenne, J., Nuyts, J., Rega, F., Voigt, J.U., Vunckx, K., and Claus, P.
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- 2019
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9. Performance of advanced imaging modalities at diagnosis and treatment response evaluation of patients with post-transplant lymphoproliferative disorder: A systematic review and meta-analysis
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Montes de Jesus, F.M., Kwee, T.C., Nijland, M., Kahle, X.U., Huls, G., Dierckx, R.A.J.O., van Meerten, T., Gheysens, O., Dierickx, D., Vergote, V., Noordzij, W., and Glaudemans, A.W.J.M.
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- 2018
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10. Axillary staging for breast cancer during pregnancy: feasibility and safety of sentinel lymph node biopsy
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Han, S. N., Amant, F., Cardonick, E. H., Loibl, S., Peccatori, F. A., Gheysens, O., Sangalli, C. A., Nekljudova, V., Steffensen, K. Dahl, Mhallem Gziri, M., Schröder, C. P., Lok, C. A. R., Verest, A., Neven, P., Smeets, A., Pruneri, G., Cremonesi, M., Gentilini, O., and On behalf of the International Network on Cancer, Infertility and Pregnancy
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- 2018
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11. EBV-Positive and EBV-Negative Posttransplant Diffuse Large B Cell Lymphomas Have Distinct Genomic and Transcriptomic Features
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Finalet Ferreiro, J., Morscio, J., Dierickx, D., Vandenberghe, P., Gheysens, O., Verhoef, G., Zamani, M., Tousseyn, T., and Wlodarska, I.
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- 2016
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12. A role of FDG PET/CT for Response Assessment in Large Vessel Disease?
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Treglia, G., Albano, D., Dondi, F., Bertagna, F., and Gheysens, O.
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Humans ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography/methods ,Positron-Emission Tomography ,Vasculitis ,Radiopharmaceuticals - Abstract
Currently, a large amount of evidence-based data clearly demonstrates the usefulness of [ 18 F]FDG PET/CT in the diagnosis of several infectious and inflammatory diseases, including those related to the large vessels. The aim of this article is to clarify whether, beyond initial diagnosis, [ 18 F]FDG PET/CT may have a role in treatment response assessment in inflammatory or infectious diseases of the large vessels, including large vessel vasculitis, vascular graft infection, retroperitoneal fibrosis/chronic periaortitis and infective native aortic aneurysms. Rapidly accumulating data suggest that [ 18 F]FDG PET/CT could be a valuable imaging method for therapy monitoring in some infectious and inflammatory diseases of large vessels. The available data, albeit preliminary, indicate that [ 18 F]FDG PET/CT could even play a pivotal role in the management of these diseases, leading to better drug dosage, confirmation of the usefulness of the treatment, and early modification of the therapeutic strategy. However, to date, the role of [ 18 F]FDG PET/CT for treatment assessment in large vessel diseases, in particular large vessel vasculitis, is not clearly defined and well-designed prospective studies are needed to confirm its possible role in treatment monitoring and treatment guidance.
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- 2023
13. Pirfenidone: A Potential New Therapy for Restrictive Allograft Syndrome?
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Vos, R., Verleden, S.E., Ruttens, D., Vandermeulen, E., Yserbyt, J., Dupont, L.J., Van Raemdonck, D.E., De Raedt, N., Gheysens, O., De Jong, P.A., Verleden, G.M., and Vanaudenaerde, B.M.
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- 2013
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14. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0
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Lopci, E, Hicks, R J, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, R D, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, A W J M, Weber, W, Wahl, R L, Scott, A M, Pandit-Taskar, N, Aide, N, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, and UCL - (SLuc) Service de médecine nucléaire
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Positron emission tomography ,PET/CT ,Australia ,treatment response ,Molecular Imaging ,Fluorodeoxyglucose F18 ,Neoplasms ,Positron Emission Tomography Computed Tomography ,Humans ,immunotherapy ,Nuclear Medicine ,[18F]FDG ,Societies ,guideline ,malignant tumors - Abstract
The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help advance the science of nuclear medicine and improve service to patients. Existing standards/guidelines will be reviewed for revision or renewal, as appropriate, on their fifth anniversary or sooner, if indicated. Each standard/guideline, representing a policy statement by the EANM/SNMMI/ANZSNM, has undergone a thorough consensus process, entailing extensive review. These societies recognize that the safe and effective use of diagnostic nuclear medicine imaging requires particular training and skills, as described in each document. These standards/guidelines are educational tools designed to assist practitioners in providing appropriate and effective nuclear medicine care for patients. These guidelines are consensus documents based on current knowledge. They are not intended to be inflexible rules or requirements of practice, nor should they be used to establish a legal standard of care. For these reasons and those set forth below, the EANM, SNMMI and ANZSNM caution against the use of these standards/guidelines in litigation in which the clinical decisions of a practitioner are called into question. The ultimate judgment regarding the propriety of any specific procedure or course of action must be made by medical professionals considering the unique circumstances of each case. Thus, there is no implication that an action differing from what is laid out in the guidelines/procedure standards, standing alone, is below standard of care. To the contrary, a conscientious practitioner may responsibly adopt a course of action different from that set forth in the standards/guidelines when, in the reasonable judgment of the practitioner, such course of action is indicated by the condition of the patient, limitations of available resources or advances in knowledge or technology subsequent to publication of the guidelines/procedure standards. The practice of medicine involves not only the science, but also the art of dealing with the prevention, diagnosis, alleviation and treatment of disease. The variety and complexity of human conditions make it impossible for general guidelines to consistently allow for an accurate diagnosis to be reached or a particular treatment response to be predicted. Therefore, it should be recognized that adherence to these standards/ guidelines will not ensure a successful outcome. All that should be expected is that practitioners follow a reasonable course of action, based on their level of training, current knowledge, clinical practice guidelines, available resources and the needs/context of the patient being treated. The sole purpose of these guidelines is to assist practitioners in achieving this objective. The present guideline/procedure standard was developed collaboratively by the EANM, the SNMMI and the ANZSNM, with the support of international experts in the field. They summarize also the views of the Oncology and Theranostics and the Inflammation and Infection Committees of the EANM, as well as the procedure standards committee of the SNMMI, and reflect recommendations for which the EANM and SNMMI cannot be held responsible. The recommendations should be taken into the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions.
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- 2022
15. Noninvasive Molecular Imaging of Small Living Subjects Using Raman Spectroscopy
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Keren, S., Zavaleta, C., Cheng, Z., de la Zerda, A., Gheysens, O., and Gambhir, S. S.
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- 2008
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16. Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe
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Williams M. C., Shaw L., Hirschfeld C. B., Maurovich-Horvat P., Norgaard B. L., Pontone G., Jimenez-Heffernan A., Sinitsyn V., Sergienko V., Ansheles A., Bax J. J., Buechel R., Milan E., Slart R. H. J. A., Nicol E., Bucciarelli-Ducci C., Pynda Y., Better N., Cerci R., Dorbala S., Raggi P., Villines T. C., Vitola J., Malkovskiy E., Goebel B., Cohen Y., Randazzo M., Pascual T. N. B., Dondi M., Paez D., Einstein A. J., Nasery M. N., Goda A., Shirka E., Benlabgaa R., Bouyoucef S., Medjahedi A., Nailli Q., Agolti M., Aguero R. N., Del Carmen Alak M., Alberguina L. G., Arronada G., Astesiano A., Norton C. B., Benteo P., Blanco J., Bonelli J. M., Bustos J. J., Cabrejas R., Cachero J., Campisi R., Canderoli A., Carames S., Carrascosa P., Castro R., Cendoya O., Cognigni L. M., Collaud C., Cortes C., Courtis J., Cragnolino D., Daicz M., De La Vega A., De Maria S. T., Del Riego H., Dettori F., Deviggiano A., Dragonetti L., Embon M., Enriquez R. E., Ensinas J., Faccio F., Facello A., Garofalo D., Geronazzo R., Gonza N., Gutierrez L., Guzzo M. A., Hasbani V., Huerin M., Jager V., Lewkowicz J. M., De Munain M. N. A. L., Lotti J. M., Marquez A., Masoli O., Masoli O. H., Mastrovito E., Mayoraz M., Melado G. E., Mele A., Merani M. F., Meretta A. H., Molteni S., Montecinos M., Noguera E., Novoa C., Sueldo C. P., Ascani S. P., Pollono P., Pujol M. P., Radzinschi A., Raimondi G., Redruello M., Rodriguez M., Romero R. L., Acuna A. R., Rovaletti F., Miguel L. S., Solari L., Strada B., Traverso S., Traverzo S. S., Del Huerto Velazquez Espeche M., Weihmuller J. S., Wolcan J., Zeffiro S., Sakanyan M., Beuzeville S., Boktor R., Butler P., Calcott J., Carr L., Chan V., Chao C., Chong W., Dobson M., Downie D., Dwivedi G., Elison B., Engela J., Francis R., Gaikwad A., Basavaraj A. G., Goodwin B., Greenough R., Hamilton-Craig C., Hsieh V., Joshi S., Lederer K., Lee K., Lee J., Magnussen J., Mai N., Mander G., Murton F., Nandurkar D., Neill J., O'Rourke E., O'Sullivan P., Pandos G., Pathmaraj K., Pitman A., Poulter R., Premaratne M., Prior D., Ridley L., Rutherford N., Salehi H., Saunders C., Scarlett L., Seneviratne S., Shetty D., Shrestha G., Shulman J., Solanki V., Stanton T., Stuart M., Stubbs M., Swainson I., Taubman K., Taylor A., Thomas P., Unger S., Upton A., Vamadevan S., Van Gaal W., Verjans J., Voutnis D., Wayne V., Wilson P., Wong D., Wong K., Younger J., Feuchtner G., Mirzaei S., Weiss K., Maroz-Vadalazhskaya N., Gheysens O., Homans F., Moreno-Reyes R., Pasquet A., Roelants V., Van De Heyning C. M., Rios R. A., Soldat-Stankovic V., Stankovic S., Siqueira M. H. A., Almeida A., Togni P. H. A., Andrade J. H., Andrade L., Anselmi C., Araujo R., Azevedo G., Bezerra S., Biancardi R., Grossman G. B., Brandao S., Pianta D. B., Carreira L., Castro B., Chang T., Cunali F., Cury R., Dantas R., De Amorim Fernandes F., De Lorenzo A., De MacEdo Filho R., Erthal F., Fernandes F., Fernandes J., De Souza T. F., Alves W. F., Ghini B., Goncalves L., Gottlieb I., Hadlich M., Kameoka V., Lima R., Lima A., Lopes R. W., E Silva R. M., Magalhaes T., Silva F. M., Mastrocola L. E., Medeiros F., Meneghetti J. C., Naue V., Naves D., Nolasco R., Nomura C., Oliveira J. B., Paixao E., De Carvalho F. P., Pinto I., Possetti P., Quinta M., Ramos R. R. N., Rocha R., Rodrigues A., Rodrigues C., Romantini L., Sanches A., Santana S., Da Silva L. S., Schvartzman P., Matushita C. S., Senra T., Shiozaki A., De Siqueira M. E. M., Siqueira C., Smanio P., Soares C. E., Soares J., Bittencourt M. S., Spiro B., Mesquita C. T., Torreao J., Torres R., Uellendahl M., Monte G. U., Verissimo O., Cabeda E. V., Pedras F. V., Waltrick R., Zapparoli M., Naseer H., Garcheva-Tsacheva M., Kostadinova I., Theng Y., Abikhzer G., Barette R., Chow B., Dabreo D., Friedrich M., Garg R., Hafez M. N., Johnson C., Kiess M., Leipsic J., Leung E., Miller R., Oikonomou A., Probst S., Roifman I., Small G., Tandon V., Trivedi A., White J., Zukotynski K., Canessa J., Munoz G. C., Concha C., Hidalgo P., Lovera C., Massardo T., Vargas L. S., Abad P., Arturo H., Ayala S., Benitez L., Cadena A., Caicedo C., Moncayo A. C., Gomez S., Villamil C. T. G., Jaimes C., Londono J., Blair J. L. L., Pabon L., Pineda M., Rojas J. C., Ruiz D., Escobar M. V., Vasquez A., Vergel D., Zuluaga A., Gamboa I. B., Castro G., Gonzalez U., Baric A., Batinic T., Franceschi M., Hrabak M., Jukic M., Medakovic P., Persic V., Prpic M., Punda A., Batista J. F., Lauchy J. M. G., Gutierrez Y. M., Menendez R., Peix A., Rochela L., Panagidis C., Petrou I., Engelmann V., Kaminek M., Kincl V., Lang O., Simanek M., Abdulla J., Bottcher M., Christensen M., Gormsen L. C., Hasbak P., Hess S., Holdgaard P., Johansen A., Kyhl K., Ovrehus K. A., Sand N. P. R., Steffensen R., Thomassen A., Zerahn B., Perez A., Velez G. A. E., Velez M. S., Aziz I. S. A., Abougabal M., Ahmed T., Allam A., Asfour A., Hassan M., Hassan A., Ibrahim A., Kaffas S., Kandeel A., Ali M. M., Mansy A., Maurice H., Nabil S., Shaaban M., Flores A. C., Poksi A., Knuuti J., Kokkonen V., Larikka M., Uusitalo V., Bailly M., Burg S., Deux J. -F., Habouzit V., Hyafil F., Lairez O., Proffit F., Regaieg H., Sarda-Mantel L., Tacher V., Schneider R. P., Ayetey H., Angelidis G., Archontaki A., Chatziioannou S., Datseris I., Fragkaki C., Georgoulias P., Koukouraki S., Koutelou M., Kyrozi E., Repasos E., Stavrou P., Valsamaki P., Gonzalez C., Gutierrez G., Maldonado A., Buga K., Garai I., Schmidt E., Szilveszter B., Varady E., Banthia N., Bhagat J. K., Bhargava R., Bhat V., Bhatia M., Choudhury P., Chowdekar V. S., Irodi A., Jain S., Joseph E., Kumar S., Mahapatra G., Mitra D., Mittal B. R., Ozair A., Patel C., Patel T., Patel R., Patel S., Saxena S., Sengupta S., Singh S., Singh B., Sood A., Verma A., Affandi E., Alam P. S., Edison E., Gunawan G., Hapkido H., Hidayat B., Huda A., Mukti A. P., Prawiro D., Soeriadi E. A., Syawaluddin H., Albadr A., Assadi M., Emami F., Houshmand G., Maleki M., Rostami M. T., Zakavi S. R., Zaid E. A., Agranovich S., Arnson Y., Bar-Shalom R., Frenkel A., Knafo G., Lugassi R., Moalem I. S. M., Mor M., Muskal N., Ranser S., Shalev A., Albano D., Alongi P., Arnone G., Bagatin E., Baldari S., Bauckneht M., Bertelli P., Bianco F., Bonfiglioli R., Boni R., Bruno A., Bruno I., Busnardo E., Califaretti E., Camoni L., Carnevale A., Casoni R., Cavallo A. U., Cavenaghi G., Chierichetti F., Chiocchi M., Cittanti C., Colletta M., Conti U., Cossu A., Cuocolo A., Cuzzocrea M., De Rimini M. L., De Vincentis G., Del Giudice E., Del Torto A., Della Tommasina V., Durmo R., Erba P. A., Evangelista L., Faletti R., Faragasso E., Farsad M., Ferro P., Florimonte L., Frantellizzi V., Fringuelli F. M., Gatti M., Gaudiano A., Gimelli A., Giubbini R., Giuffrida F., Ialuna S., Laudicella R., Leccisotti L., Leva L., Liga R., Liguori C., Longo G., Maffione M., Mancini M. E., Marcassa C., Nardi B., Pacella S., Pepe G., Pulizzi S., Quartuccio N., Rampin L., Ricci F., Rossini P., Rubini G., Russo V., Sacchetti G. M., Sambuceti G., Scarano M., Sciagra R., Sperandio M., Stefanelli A., Ventroni G., Zoboli S., Baugh D., Chambers D., Madu E., Nunura F., Asano H., Chimura C. M., Fujimoto S., Fujisue K., Fukunaga T., Fukushima Y., Fukuyama K., Hashimoto J., Ichikawa Y., Iguchi N., Imai M., Inaki A., Ishimura H., Isobe S., Kadokami T., Kato T., Kudo T., Kumita S., Maruno H., Mataki H., Miyagawa M., Morimoto R., Moroi M., Nagamachi S., Nakajima K., Nakata T., Nakazato R., Nanasato M., Naya M., Norikane T., Ohta Y., Okayama S., Okizaki A., Otomi Y., Otsuka H., Saito M., Sakata S. Y., Sarai M., Sato D., Shiraishi S., Suwa Y., Takanami K., Takehana K., Taki J., Tamaki N., Taniguchi Y., Teragawa H., Tomizawa N., Tsujita K., Umeji K., Wakabayashi Y., Yamada S., Yamazaki S., Yoneyama T., Rawashdeh M., Batyrkhanov D., Dautov T., Makhdomi K., Ombati K., Alkandari F., Garashi M., Coie T. L., Rajvong S., Kalinin A., Kalnina M., Haidar M., Komiagiene R., Kviecinskiene G., Mataciunas M., Vajauskas D., Picard C., Karim N. K. A., Reichmuth L., Samuel A., Allarakha M. A., Naojee A. S., Alexanderson-Rosas E., Barragan E., Becerril A., Gonzalez-Montecinos, Cabada M., Rodriguez D. C., Carvajal-Juarez I., Cortes V., Cortes F., De La Pena E., Gama-Moreno M., Gonzalez L., Ramirez N. G., Jimenez-Santos M., Matos L., Monroy E., Morelos M., Ornelas M., Ramirez J. A. O., Preciado-Anaya A., Preciado-Gutierrez O. U., Barragan A. P., Uvera S. G. R., Sandoval S., Tomas M. S., Sierra-Galan L. M., Siu S., Vallejo E., Valles M., Faraggi M., Sereegotov E., Ilic S., Ben-Rais N., Alaoui N. I., Taleb S., Myo K. P. P., Thu P. S., Ghimire R. K., Rajbanshi B., Barneveld P., Glaudemans A., Habets J., Koopmans K. P., Manders J., Pool S., Scholte A., Scholtens A., Slart R., Thimister P., Van Asperen E. -J., Veltman N., Verschure D., Wagenaar N., Edmond J., Ellis C., Johnson K., Keenan R., Kueh S. H., Occleshaw C., Sasse A., To A., Van Pelt N., Young C., Cuadra T., Vanegas H. B. R., Soli I. A., Issoufou D. M., Ayodele T., Madu C., Onimode Y., Efros-Monsen E., Forsdahl S. H., Dimmen J. -M. H., Jorgensen A., Krohn I., Lovhaugen P., Braten A. T., Al Dhuhli H., Al Kindi F., Al-Bulushi N., Jawa Z., Tag N., Afzal M. S., Fatima S., Younis M. N., Riaz M., Saadullah M., Herrera Y., Lenturut-Katal D., Vazquez M. C., Ortellado J., Akhter A., Cao D., Cheung S., Dai X., Gong L., Han D., Hou Y., Li C., Li T., Li D., Li S., Liu J., Liu H., Lu B., Ng M. Y., Sun K., Tang G., Wang J., Wang X., Wang Z. -Q., Wang Y., Wu J., Wu Z., Xia L., Xiao J., Xu L., Yang Y., Yin W., Yu J., Yuan L., Zhang T., Zhang L., Zhang Y. -G., Zhang X., Zhu L., Alfaro A., Abrihan P., Barroso A., Cruz E., Gomez M. R., Magboo V. P., Medina J. M., Obaldo J., Pastrana D., Pawhay C. M., Quinon A., Tang J. M., Tecson B., Uson K. J., Uy M., Kostkiewicz M., Kunikowska J., Bettencourt N., Cantinho G., Ferreira A., Syed G., Arnous S., Atyani S., Byrne A., Gleeson T., Kerins D., Meehan C., Murphy D., Murphy M., Murray J., O'Brien J., Bang J. -I., Bom H., Cho S. -G., Hong C. M., Jang S. J., Jeong Y. H., Kang W. J., Kim J. -Y., Namgung C. K., So Y., Won K. S., Majstorov V., Vavlukis M., Salobir B. G., Stalc M., Benedek T., Benedek I., Mititelu R., Stan C. A., Dariy O., Drozdova O., Gagarina N., Gulyaev V. M., Itskovich I., Karalkin A., Kokov A., Migunova E., Pospelov V., Ryzhkova D., Saifullina G., Sazonova S., Shurupova I., Trifonova T., Ussov W. Y., Vakhromeeva M., Valiullina N., Zavadovsky K., Zhuravlev K., Alasnag M., Okarvi S., Saranovic D. S., Keng F., See J. H. J., Sekar R., Yew M. S., Vondrak A., Bejai S., Bennie G., Bester R., Engelbrecht G., Evbuomwan O., Gongxeka H., Vuuren M. J., Kaplan M., Khushica P., Lakhi H., Louw L., Malan N., Milos K., Modiselle M., More S., Naidoo M., Scholtz L., Vangu M., Aguade-Bruix S., Blanco I., Cabrera A., Camarero A., Casans-Tormo I., Cuellar-Calabria H., Flotats A., Canamero M. E. F., Garcia M. E., Leta R., Diaz J. L., Lumbreras L., Marquez-Cabeza J. J., Martin F., De Alegria A. M., Medina F., Canal M. P., Peiro V., Pubul-Nunez V., Madrid J. I. R., Rey C. R., Perez R. R., Ruiz J., Hernandez G. S., Sevilla A., Zeidan N., Nanayakkara D., Udugama C., Simonsson M., Alkadhi H., Buechel R. R., Burger P., Ceriani L., De Boeck B., Grani C., De Saint Lager Lucas A. J., Kamani C. H., Kawel-Boehm N., Manka R., Prior J. O., Rominger A., Vallee J. -P., Khiewvan B., Premprabha T., Thientunyakit T., Sellem A., Kir K. M., Sayman H., Sebikali M. J., Muyinda Z., Kmetyuk Y., Korol P., Mykhalchenko O., Pliatsek V., Satyr M., Albalooshi B., Hassan M. I. 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A, Dougan, J, Fairbairn, T, Farrugia, A, Gopalan, D, Gummow, A, Ramkumar, P, Hamilton, M, Harbinson, M, Hartley, T, Hudson, B, Joshi, N, Kay, M, Kelion, A, Khokhar, A, Kitt, J, Low, C, Mak, S, Marousa, N, Martin, J, Mcalindon, E, Menezes, L, Morgan-Hughes, G, Moss, A, Murray, A, Patel, D, Peebles, C, Pugliese, F, Rodrigues, J, Rofe, C, Sabharwal, N, Schofield, R, Semple, T, Sharma, N, Strouhal, P, Subedi, D, Topping, W, Tweed, K, Weir-Mccall, J, Abbara, S, Abbasi, T, Abbott, B, Abohashem, S, Abramson, S, Al-Abboud, T, Al-Mallah, M, Almousalli, O, Ananthasubramaniam, K, Kumar, M, Askew, J, Attanasio, L, Balmer-Swain, M, Bayer, R, Bernheim, A, Bhatti, S, Bieging, E, Blankstein, R, Bloom, S, Blue, S, Bluemke, D, Borges, A, Branch, K, Bravo, P, Brothers, J, Budoff, M, Bullock-Palmer, R, Burandt, A, Burke, F, Bush, K, Candela, C, Capasso, E, Cavalcante, J, Chang, D, Chatterjee, S, Chatzizisis, Y, Cheezum, M, Chen, T, Chen, J, Chen, M, Choi, A, Clarcq, J, Cordero, A, Crim, M, Danciu, S, 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P, Osman, M, Parwani, P, Passen, E, Patel, A, Patil, P, Paul, R, Phillips, L, Polsani, V, Poludasu, R, Pomerantz, B, Porter, T, Prentice, R, Pursnani, A, Rabbat, M, Ramamurti, S, Rich, F, Luna, H, Robinson, A, Robles, K, Rodriguez, C, Rorie, M, Rumberger, J, Russell, R, Sabra, P, Sadler, D, Schemmer, M, Schoepf, U, Shah, S, Shah, N, Shanbhag, S, Sharma, G, Shayani, S, Shirani, J, Shivaram, P, Sigman, S, Simon, M, Slim, A, Smith, D, Smith, A, Soman, P, Srichai-Parsia, M, Streeter, J, Albert, T, Tawakol, A, Thomas, D, Thompson, R, Torbet, T, Trinidad, D, Ullery, S, Unzek, S, Uretsky, S, Vallurupalli, S, Verma, V, Waller, A, Wang, E, Ward, P, Weissman, G, Wesbey, G, White, K, Winchester, D, Wolinsky, D, Yost, S, Zgaljardic, M, Alonso, O, Beretta, M, Ferrando, R, Kapitan, M, Mut, F, Djuraev, O, Rozikhodjaeva, G, Ngoc, H, Mai, S, Nguyen, X, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Translational Immunology Groningen (TRIGR), and Cardiovascular Centre (CVC)
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INCAPS COVID Investigators Group ,cardiac imaging techniques ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,Practice Patterns ,Disease ,Cardiovascular ,coronary artery disease ,COVID-19 ,Cardiac Imaging Techniques ,Cardiologists ,Europe ,Health Care Surveys ,Healthcare Disparities ,Heart Diseases ,Humans ,Practice Patterns, Physicians' ,Predictive Value of Tests ,Gross domestic product ,Human health ,cardiovascular disease ,Pandemic ,Medicine ,cardiovascular imaging ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina ,cardiac imaging technique ,Predictive value of tests ,Cardiology and Cardiovascular Medicine ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Infektologija ,cardiac disease ,Coronavirus disease 2019 (COVID-19) ,Independent predictor ,cardiac imaging ,NO ,Imaging diagnosis ,Diseases of the circulatory (Cardiovascular) system ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine ,Physicians' ,business.industry ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Infectology ,RC666-701 ,HOSPITALIZATIONS ,business ,Health Care Delivery, Economics and Global Health Care ,Demography - Abstract
ObjectivesWe aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe.MethodsThe online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries.ResultsCentres in Northern and Southern Europe were more likely to cancel all outpatient activities compared with Western and Eastern Europe. There was a greater reduction in total procedure volumes in Europe compared with the rest of the world in March 2020 (45% vs 41%, p=0.003), with a more marked reduction in Southern Europe (58%), but by April 2020 this was similar in Europe and the rest of the world (69% vs 63%, p=0.261). Regional variations were apparent between imaging modalities, but the largest reductions were in Southern Europe for nearly all modalities. In March 2020, location in Southern Europe was the only independent predictor of the reduction in procedure volume. However, in April 2020, lower gross domestic product and higher COVID-19 deaths were the only independent predictors.ConclusionThe first wave of the COVID-19 pandemic had a significant impact on care of patients with cardiac disease, with substantial regional variations in Europe. This has potential long-term implications for patients and plans are required to enable the diagnosis of non-COVID-19 conditions during the ongoing pandemic.
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- 2021
17. Functional and molecular correlative imaging in a patient with amyloidosis
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Pagourelias, E., Delforge, M., Claus, P., and Gheysens, O.
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- 2016
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18. Mycobacterium genavense infection in a solid organ recipient: a diagnostic and therapeutic challenge
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Ombelet, S., Van Wijngaerden, E., Lagrou, K., Tousseyn, T., Gheysens, O., Droogne, W., Doubel, P., Kuypers, D., and Claes, K. J.
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- 2016
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19. Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors.
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Lopci, E., Aide, N., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W. A., Van den Abbeele, A. D., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Hicks, R. J.
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- 2022
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20. Poster session 5: Friday 5 December 2014, 14: 00–18: 00Location: Poster area
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Turco, A, Duchenne, J, Nuyts, J, Gheysens, O, Voigt, J-U, Claus, P, and Vunckx, K
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- 2014
21. Semi-Quantitative Characterization of Post-Transplant Lymphoproliferative Disorder Morphological Subtypes with [F]FDG PET/CT
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Montes de Jesus, Felipe, Vergote, V, Noordzij, W, Dierickx, D, Dierckx, R A J O, Diepstra, A, Tousseyn, T, Gheysens, O, Kwee, T C, Deroose, C M, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, and UCL - (SLuc) Centre du cancer
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surgical procedures, operative ,2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography ,hemic and lymphatic diseases ,standardized uptake value ,semi-quantification ,post-transplant lymphoproliferative disorder ,FDG-PET/CT - Abstract
Post-transplant lymphoproliferative disorder (PTLD) is a complication of organ transplantation classified according to the WHO as nondestructive, polymorphic, monomorphic, and classic Hodgkin Lymphoma subtypes. In this retrospective study, we investigated the potential of semi-quantitative 2-[F]fluoro-2-deoxy-D-glucose ([F]FDG) PET/computed tomography (CT)-based parameters to differentiate between the PTLD morphological subtypes. 96 patients with histopathologically confirmed PTLD and baseline [F]FDG PET/CT between 2009 and 2019 were included. Extracted semi-quantitative measurements included: Maximum, peak, and mean standardized uptake value (SUV, SUV, and SUV). Median SUVs were highest for monomorphic PTLD followed by polymorphic and nondestructive subtypes. The median SUV at the biopsy site was significantly higher in monomorphic PTLD (17.8, interquartile range (IQR):16) than in polymorphic subtypes (9.8, IQR:13.4) and nondestructive (4.1, IQR:6.1) ( = 0.04 and ≤ 0.01, respectively). An SUV ≥ 24.8 was always indicative of a monomorphic PTLD in our dataset. Nevertheless, there was a considerable overlap in SUV across the different morphologies. The median SUV at the biopsy site was significantly higher in monomorphic PTLD than polymorphic and nondestructive subtypes. However, due to significant SUV overlap across the different subtypes, these values may only serve as an indication of PTLD morphology, and SUV-based parameters cannot replace histopathological classification.
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- 2021
22. Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study
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Kudo, T., Lahey, R., Hirschfeld, C.B., Williams, M.C., Lu, B., Alasnag, M., Bhatia, M., Henry Bom, H.-., Dautov, T., Fazel, R., Karthikeyan, G., Keng, F.Y.J., Rubinshtein, R., Better, N., Cerci, R.J., Dorbala, S., Raggi, P., Shaw, L.J., Villines, T.C., Vitola, J.V., Choi, A.D., Malkovskiy, E., Goebel, B., Cohen, Y.A., Randazzo, M., Pascual, T.N.B., Pynda, Y., Dondi, M., Paez, D., Einstein, A.J., Cerci, R., Hinterleitner, G., Lu, Y., Morozova, O., Xu, Z., Cohen, Y., Choi, A., Lopez-Mattei, J., Parwani, P., Nasery, M.N., Goda, A., Shirka, E., Benlabgaa, R., Bouyoucef, S., Medjahedi, A., Nailli, Q., Agolti, M., Aguero, R.N., Alak, M.D.C., Alberguina, L.G., Arronada, G., Astesiano, A., Norton, C.B., Benteo, P., Blanco, J., Bonelli, J.M., Bustos, J.J., Cabrejas, R., Cachero, J., Campisi, R., Canderoli, A., Carames, S., Carrascosa, P., Castro, R., Cendoya, O., Cognigni, L.M., Collaud, C., Cortes, C., Courtis, J., Cragnolino, D., Daicz, M., De La Vega, A., De Maria, S.T., Del Riego, H., Dettori, F., Deviggiano, A., Dragonetti, L., Embon, M., Enriquez, R.E., Ensinas, J., Faccio, F., Facello, A., Garofalo, D., Geronazzo, R., Gonza, N., Gutierrez, L., Guzzo, M.A., Hasbani, V., Huerin, M., Jager, V., Lewkowicz, J.M., Lopez De Munain, M.N.A., Lotti, J.M., Marquez, A., Masoli, O., Masoli, O.H., Mastrovito, E., Mayoraz, M., Melado, G.E., Mele, A., Merani, M.F., Meretta, A.H., Molteni, S., Montecinos, M., Noguera, E., Novoa, C., Sueldo, C.P., Ascani, S.P., Pollono, P., Pujol, M.P., Radzinschi, A., Raimondi, G., Redruello, M., Rodriguez, M., Romero, R.L., Acuna, A.R., Rovaletti, F., San Miguel, L., Solari, L., Strada, B., Traverso, S., Traverzo, S.S., Espeche, M.D.H.V., Weihmuller, J.S., Wolcan, J., Zeffiro, S., Sakanyan, M., Beuzeville, S., Boktor, R., Butler, P., Calcott, J., Carr, L., Chan, V., Chao, C., Chong, W., Dobson, M., Downie, D.A., Dwivedi, G., Elison, B., Engela, J., Francis, R., Gaikwad, A., Basavaraj, A.G., Goodwin, B., Greenough, R., Hamilton-Craig, C., Hsieh, V., Joshi, S., Lederer, K., Lee, K., Lee, J., Magnussen, J., Mai, N., Mander, G., Murton, F., Nandurkar, D., Neill, J., O'Rourke, E., O'Sullivan, P., Pandos, G., Pathmaraj, K., Pitman, A., Poulter, R., Premaratne, M., Prior, D., Ridley, L., Rutherford, N., Salehi, H., Saunders, C., Scarlett, L., Seneviratne, S., Shetty, D., Shrestha, G., Shulman, J., Solanki, V., Stanton, T., Stuart, M., Stubbs, M., Swainson, I., Taubman, K., Taylor, A., Thomas, P., Unger, S., Upton, A., Vamadevan, S., Van Gaal, W., Verjans, J., Voutnis, D., Wayne, V., Wilson, P., Wong, D., Wong, K., Younger, J., Feuchtner, G., Mirzaei, S., Weiss, K., Maroz-Vadalazhskaya, N., Gheysens, O., Homans, F., Moreno-Reyes, R., Pasquet, A., Roelants, V., Van De Heyning, C.M., Rios, R.A., Soldat-Stankovic, V., Stankovic, S., Albernaz Siqueira, M.H., Almeida, A., Alves Togni, P.H., Andrade, J.H., Andrade, L., Anselmi, C., Araujo, R., Azevedo, G., Bezerra, S., Biancardi, R., Grossman, G.B., Brandao, S., Pianta, D.B., Carreira, L., 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Lenturut-Katal, D., Vazquez, M.C., Ortellado, J., Akhter, A., Cao, D., Cheung, S., Dai, X., Gong, L., Han, D., Hou, Y., Li, C., Li, T., Li, D., Li, S., Liu, J., Liu, H., M. Y., N., Sun, K., Tang, G., Wang, J., Wang, X., Wang, Z.-., Wang, Y., Wu, J., Wu, Z., Xia, L., Xiao, J., Xu, L., Yang, Y., Yin, W., Yu, J., Yuan, L., Zhang, T., Zhang, L., Zhang, Y.-., Zhang, X., Zhu, L., Alfaro, A., Abrihan, P., Barroso, A., Cruz, E., Gomez, M.R., Magboo, V.P., Medina, J.M., Obaldo, J., Pastrana, D., Pawhay, C.M., Quinon, A., Tang, J.M., Tecson, B., Uson, K.J., Uy, M., Kostkiewicz, M., Kunikowska, J., Bettencourt, N., Cantinho, G., Ferreira, A., Syed, G., Arnous, S., Atyani, S., Byrne, A., Gleeson, T., Kerins, D., Meehan, C., Murphy, D., Murphy, M., Murray, J., O'Brien, J., Bang, J.-., Bom, H., Cho, S.-., Hong, C.M., Jang, S.J., Jeong, Y.H., Kang, W.J., Kim, J.-., Namgung, C.K., So, Y., Won, K.S., Majstorov, V., Vavlukis, M., Salobir, B.G., Stalc, M., Benedek, T., Benedek, I., Mititelu, R., Stan, C.A., Ansheles, A., Dariy, O., Drozdova, O., Gagarina, N., Gulyaev, V.M., Itskovich, I., Karalkin, A., Kokov, A., Migunova, E., Pospelov, V., Ryzhkova, D., Saifullina, G., Sazonova, S., Sergienko, V., Shurupova, I., Trifonova, T., Ussov, W.Y., Vakhromeeva, M., Valiullina, N., Zavadovsky, K., Zhuravlev, K., Okarvi, S., Saranovic, D.S., Keng, F., Jason See, J.H., Sekar, R., Yew, M.S., Vondrak, A., Bejai, S., Bennie, G., Bester, R., Engelbrecht, G., Evbuomwan, O., Gongxeka, H., Vuuren, M.J., Kaplan, M., Khushica, P., Lakhi, H., Louw, L., Malan, N., Milos, K., Modiselle, M., More, S., Naidoo, M., Scholtz, L., Vangu, M., Aguade-Bruix, S., Blanco, I., Cabrera, A., Camarero, A., Casans-Tormo, I., Cuellar-Calabria, H., Flotats, A., Fuentes Canamero, M.E., Garcia, M.E., Jimenez-Heffernan, A., Leta, R., Diaz, J.L., Lumbreras, L., Marquez-Cabeza, J.J., Martin, F., Martinez de Alegria, A., Medina, F., Canal, M.P., Peiro, V., Pubul-Nunez, V., Rayo Madrid, J.I., Rey, C.R., Perez, R.R., Ruiz, J., Hernandez, G.S., Sevilla, A., Zeidan, N., Nanayakkara, D., Udugama, C., Simonsson, M., Alkadhi, H., Buechel, R.R., Burger, P., Ceriani, L., De Boeck, B., Grani, C., Juillet de Saint Lager Lucas, A., Kamani, C.H., Kawel-Boehm, N., Manka, R., Prior, J.O., Rominger, A., Vallee, J.-., Khiewvan, B., Premprabha, T., Thientunyakit, T., Sellem, A., Kir, K.M., Sayman, H., Sebikali, M.J., Muyinda, Z., Kmetyuk, Y., Korol, P., Mykhalchenko, O., Pliatsek, V., Satyr, M., Albalooshi, B., Ahmed Hassan, M.I., Anderson, J., Bedi, P., Biggans, T., Bularga, A., Bull, R., Burgul, R., Carpenter, J.-., Coles, D., Cusack, D., Deshpande, A., Dougan, J., Fairbairn, T., Farrugia, A., Gopalan, D., Gummow, A., Ramkumar, P.G., Hamilton, M., Harbinson, M., Hartley, T., Hudson, B., Joshi, N., Kay, M., Kelion, A., Khokhar, A., Kitt, J., Low, C., Mak, S.M., Marousa, N., Martin, J., Mcalindon, E., Menezes, L., Morgan-Hughes, G., Moss, A., Murray, A., Nicol, E., Patel, D., Peebles, C., Pugliese, F., Luis Rodrigues, J.C., Rofe, C., Sabharwal, N., Schofield, R., Semple, T., Sharma, N., Strouhal, P., Subedi, D., Topping, W., Tweed, K., Weir-Mccall, J., Abbara, S., Abbasi, T., Abbott, B., Abohashem, S., Abramson, S., Al-Abboud, T., Al-Mallah, M., Almousalli, O., Ananthasubramaniam, K., Kumar, M.A., Askew, J., Attanasio, L., Balmer-Swain, M., Bayer, R.R., Bernheim, A., Bhatti, S., Bieging, E., Blankstein, R., Bloom, S., Blue, S., Bluemke, D., Borges, A., Branch, K., Bravo, P., Brothers, J., Budoff, M., Bullock-Palmer, R., Burandt, A., Burke, F.W., Bush, K., Candela, C., Capasso, E., Cavalcante, J., Chang, D., Chatterjee, S., Chatzizisis, Y., Cheezum, M., Chen, T., Chen, J., Chen, M., Clarcq, J., Cordero, A., Crim, M., Danciu, S., Decter, B., Dhruva, N., Doherty, N., Doukky, R., Dunbar, A., Duvall, W., Edwards, R., Esquitin, K., Farah, H., Fentanes, E., Ferencik, M., Fisher, D., Fitzpatrick, D., Foster, C., Fuisz, T., Gannon, M., Gastner, L., Gerson, M., Ghoshhajra, B., Goldberg, A., Goldner, B., Gonzalez, J., Gore, R., Gracia-Lopez, S., Hage, F., Haider, A., Haider, S., Hamirani, Y., Hassen, K., Hatfield, M., Hawkins, C., Hawthorne, K., Heath, N., Hendel, R., Hernandez, P., Hill, G., Horgan, S., Huffman, J., Hurwitz, L., Iskandrian, A., Janardhanan, R., Jellis, C., Jerome, S., Kalra, D., Kaviratne, S., Kay, F., Kelly, F., Khalique, O., Kinkhabwala, M., Iii, G.K., Kircher, J., Kirkbride, R., Kontos, M., Kottam, A., Krepp, J., Layer, J., Lee, S.H., Leppo, J., Lesser, J., Leung, S., Lewin, H., Litmanovich, D., Liu, Y., Magurany, K., Markowitz, J., Marn, A., Matis, S.E., Mckenna, M., Mcrae, T., Mendoza, F., Merhige, M., Min, D., Moffitt, C., Moncher, K., Moore, W., Morayati, S., Morris, M., Mossa-Basha, M., Mrsic, Z., Murthy, V., Nagpal, P., Napier, K., Nelson, K., Nijjar, P., Osman, M., Passen, E., Patel, A., Patil, P., Paul, R., Phillips, L., Polsani, V., Poludasu, R., Pomerantz, B., Porter, T., Prentice, R., Pursnani, A., Rabbat, M., Ramamurti, S., Rich, F., Luna, H.R., Robinson, A., Robles, K., Rodriguez, C., Rorie, M., Rumberger, J., Russell, R., Sabra, P., Sadler, D., Schemmer, M., Schoepf, U.J., Shah, S., Shah, N., Shanbhag, S., Sharma, G., Shayani, S., Shirani, J., Shivaram, P., Sigman, S., Simon, M., Slim, A., Smith, D., Smith, A., Soman, P., Srichai-Parsia, M.B., Streeter, J., T, A., Tawakol, A., Thomas, D., Thompson, R., Torbet, T., Trinidad, D., Ullery, S., Unzek, S., Uretsky, S., Vallurupalli, S., Verma, V., Waller, A., Wang, E., Ward, P., Weissman, G., Wesbey, G., White, K., Winchester, D., Wolinsky, D., Yost, S., Zgaljardic, M., Alonso, O., Beretta, M., Ferrando, R., Kapitan, M., Mut, F., Djuraev, O., Rozikhodjaeva, G., Le Ngoc, H., Mai, S.H., and Nguyen, X.C.
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INCAPS COVID Investigators Group ,Pediatric Research Initiative ,positron emission tomography ,CTA ,SARS-CoV-2 ,cardiac testing ,invasive coronary angiography ,Prevention ,coronavirus ,coronavirus disease-19 ,COVID-19 ,global health ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,cardiac magnetic resonance ,cardiovascular disease ,NO ,transthoracic echocardiography ,PET ,Good Health and Well Being ,severe acute respiratory syndrome-coronavirus-2 ,TTE ,ICA ,CMR ,computed tomographic angiography - Abstract
BackgroundThe coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known.ObjectivesThis study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia.MethodsThe International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and were compared to those from March 2019. Data from 180 centers across 33 Asian countries were grouped into 4 subregions for comparison.ResultsProcedure volumes decreased by 47% from March 2019 to March 2020, showing recovery from March 2020 to April 2020 in Eastern Asia, particularly in China. The majority of centers cancelled outpatient activities and increased time per study. Practice changes included implementing physical distancing and restricting visitors. Although COVID testing was not commonly performed, it was conducted in one-third of facilities in Eastern Asia. The most severe reductions in procedure volumes were observed in lower-income countries, where volumes decreased 81% from March 2019 to April2020.ConclusionsThe COVID-19 pandemic in Asia caused significant reductions in cardiovascular diagnostic procedures, particularly in low-income countries. Further studies on effects of COVID-19 on cardiovascular outcomes and changes in care delivery are warranted.
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- 2021
23. The value of F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis
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Ten Hove, D, Treglia, G, Slart, R H J A, Damman, K, Wouthuyzen-Bakker, M, Postma, D F, Gheysens, O, Borra, R J H, Mecozzi, G, van Geel, P P, Sinha, B, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, and UCL - (SLuc) Service de médecine nucléaire
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LVAD infection ,Meta-analysis ,Prosthesis-Related Infections ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography ,Positron-Emission Tomography ,18F-FDG PET/CT ,Quality of Life ,Systematic review ,Humans ,Heart-Assist Devices ,Radiopharmaceuticals ,Sensitivity and Specificity - Abstract
Left ventricular assist devices (LVADs) are increasingly used for the treatment of advanced heart failure. LVADs improve quality of life and decrease mortality, but the driveline carries substantial risk for major infections. These device-related LVAD and driveline infections are difficult to diagnose with conventional imaging. We reviewed and analysed the current literature on the additive value of F-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) imaging for the diagnosis of LVAD-related infections." We performed a systematic literature review using several databases from their inception until the 31st of December, 2019. Studies investigating the diagnostic performance of FDG-PET/CT in patients with suspected LVAD infection were retrieved. After a bias risk assessment using QUADAS-2, a study-aggregate meta-analysis was performed on a per examination-based analysis. A total of 10 studies were included in the systematic review, eight of which were also eligible for study-aggregate meta-analysis. For the meta-analysis, a total of 256 FDG-PET/CT scans, examining pump/pocket and/or driveline infection, were acquired in 230 patients. Pooled sensitivity of FDG-PET/CT was 0.95 (95% confidence interval (CI) 0.89-0.97) and pooled specificity was 0.91 (95% CI 0.54-0.99) for the diagnosis of device-related infection. For pump/pocket infection, sensitivity and specificity of FDG-PET/CT were 0.97 (95%CI 0.69-1.00) and 0.93 (95%CI 0.64-0.99), respectively. For driveline infection, sensitivity and specificity were 0.96 (95%CI 0.88-0.99) and 0.99 (95%CI 0.13-1.00) respectively. Significant heterogeneity existed across studies for specificity, mostly caused by differences in scan procedures. Predefined criteria for suspicion of LVAD and/or driveline infection were lacking in all included studies. FDG-PET/CT is a valuable tool for assessment of device-related infection in LVAD patients, with high sensitivity and high, albeit variable, specificity. Standardization of FDG-PET/CT procedures and criteria for suspected device-related LVAD infections are needed for consistent reporting of FDG-PET/CT scans.
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- 2021
24. Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy
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Chen, I Y, Gheysens, O, Ray, S, Wang, Q, Padmanabhan, P, Paulmurugan, R, Loening, A M, Rodriguez-Porcel, M, Willmann, J K, Sheikh, A Y, Nielsen, C H, Hoyt, G, Contag, C H, Robbins, R C, Biswal, S, Wu, J C, and Gambhir, S S
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- 2010
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25. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0.
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Lopci, E., Hicks, R. J., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Aide, N.
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NUCLEAR medicine ,IMMUNOTHERAPY ,ONCOLOGY ,INFLAMMATION ,COMPANION diagnostics - Abstract
Purpose: The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [
18 F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. Methods: In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. Conclusions: The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [18 F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. Preamble: The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help advance the science of nuclear medicine and improve service to patients. Existing standards/guidelines will be reviewed for revision or renewal, as appropriate, on their fifth anniversary or sooner, if indicated. Each standard/guideline, representing a policy statement by the EANM/SNMMI/ANZSNM, has undergone a thorough consensus process, entailing extensive review. These societies recognize that the safe and effective use of diagnostic nuclear medicine imaging requires particular training and skills, as described in each document. These standards/guidelines are educational tools designed to assist practitioners in providing appropriate and effective nuclear medicine care for patients. These guidelines are consensus documents based on current knowledge. They are not intended to be inflexible rules or requirements of practice, nor should they be used to establish a legal standard of care. For these reasons and those set forth below, the EANM, SNMMI and ANZSNM caution against the use of these standards/guidelines in litigation in which the clinical decisions of a practitioner are called into question. The ultimate judgment regarding the propriety of any specific procedure or course of action must be made by medical professionals considering the unique circumstances of each case. Thus, there is no implication that an action differing from what is laid out in the guidelines/procedure standards, standing alone, is below standard of care. To the contrary, a conscientious practitioner may responsibly adopt a course of action different from that set forth in the standards/guidelines when, in the reasonable judgment of the practitioner, such course of action is indicated by the condition of the patient, limitations of available resources or advances in knowledge or technology subsequent to publication of the guidelines/procedure standards. The practice of medicine involves not only the science, but also the art of dealing with the prevention, diagnosis, alleviation and treatment of disease. The variety and complexity of human conditions make it impossible for general guidelines to consistently allow for an accurate diagnosis to be reached or a particular treatment response to be predicted. Therefore, it should be recognized that adherence to these standards/ guidelines will not ensure a successful outcome. All that should be expected is that practitioners follow a reasonable course of action, based on their level of training, current knowledge, clinical practice guidelines, available resources and the needs/context of the patient being treated. The sole purpose of these guidelines is to assist practitioners in achieving this objective. The present guideline/procedure standard was developed collaboratively by the EANM, the SNMMI and the ANZSNM, with the support of international experts in the field. They summarize also the views of the Oncology and Theranostics and the Inflammation and Infection Committees of the EANM, as well as the procedure standards committee of the SNMMI, and reflect recommendations for which the EANM and SNMMI cannot be held responsible. The recommendations should be taken into the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions. [ABSTRACT FROM AUTHOR]- Published
- 2022
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26. Metabolic-structural concordance in paraneoplastic limbic encephalitis
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Goffin, K. E., Ooms, D., Ahmad, R., Demaerel, P., Van Paesschen, W., Van Laere, K., Vansteenkiste, J., Deroose, C. M., and Gheysens, O.
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- 2016
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27. A joint procedural position statement on imaging in cardiac sarcoidosis
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Slart, R. H. J. A., Glaudemans, A. W. J. M., Lancellotti, P., Hyafil, F., Blankstein, R., Schwartz, R. G., Jaber, W. A., Russell, R., Gimelli, A., Rouzet, F., Hacker, M., Gheysens, O., Plein, S., Miller, E. J., Dorbala, S., Donal, E., Sciagra, R., Bucerius, J., Verberne, H. J., Lindner, O., Ubleis, C., Agostini, D., Signore, A., Edvardsen, T., Neglia, D., Beanlands, R. S., Di Carli, M., Chareonthaitawee, P., Dilsizian, V., Soman, P., Habib, G., Delgado, V., Cardim, N., Cosyns, B., Flachskampf, F., Gerber, B., Haugaa, K., Lombardi, M., Masci, P. G., Nuclear Medicine, ACS - Amsterdam Cardiovascular Sciences, Radiology and Nuclear Medicine, Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-Research), Université de Liège, Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], CIC-IT Rennes, Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Jonchère, Laurent, INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), RS: CARIM - R3.11 - Imaging, MUMC+: DA BV Medisch Specialisten Nucleaire Geneesk (9), Beeldvorming, Biomedical Photonic Imaging, Clinical sciences, Cardio-vascular diseases, Cardiology, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Vascular Ageing Programme (VAP), Translational Immunology Groningen (TRIGR), Cardiovascular Centre (CVC), and Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)
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Male ,positron emission tomography ,diagnosis ,[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging ,Biopsy ,diagnostic ,Speckle tracking echocardiography ,030204 cardiovascular system & hematology ,Myocardial Perfusion Imaging/standards ,medical ,Multimodal Imaging ,cardiac sarcoidosis ,030218 nuclear medicine & medical imaging ,0302 clinical medicine ,X ray computed ,cardiac imaging techniques ,cardiology ,cardiomyopathies ,europe ,female ,humans ,magnetic resonance imaging ,male ,multimodal imaging ,myocardial perfusion imaging ,nuclear medicine ,positron emission tomography computed tomography ,radionuclide imaging ,sarcoidosis ,societies, medical ,united states ,practice guidelines as topic ,Positron Emission Tomography Computed Tomography ,MAGNETIC-RESONANCE ,Image Processing, Computer-Assisted ,Medicine ,echocardiography ,F-18-FDG PET ,Positron Emission Tomography Computed Tomography/standards ,ComputingMilieux_MISCELLANEOUS ,Societies, Medical ,medicine.diagnostic_test ,HYPERTROPHIC CARDIOMYOPATHY ,LATE GADOLINIUM ENHANCEMENT ,Hypertrophic cardiomyopathy ,Myocardial Perfusion Imaging ,CORTICOSTEROID-THERAPY ,imaging ,Sarcoidosis/diagnostic imaging ,General Medicine ,F 18 fdg pet ,Prognosis ,Magnetic Resonance Imaging ,3. Good health ,Europe ,Positron emission tomography ,Practice Guidelines as Topic ,Cardiology ,Nuclear Medicine/standards ,[SDV.IB]Life Sciences [q-bio]/Bioengineering ,Female ,Radiology ,Sarcoidosis ,STRAIN ECHOCARDIOGRAPHY ,Cardiology and Cardiovascular Medicine ,Cardiomyopathies ,Cardiology/standards ,Position statement ,Diagnostic Imaging ,medicine.medical_specialty ,SPECKLE-TRACKING ECHOCARDIOGRAPHY ,Systemic sarcoidosis ,SYSTEMIC SARCOIDOSIS ,Cardiac sarcoidosis ,fluorodeoxyglucose ,Imaging Sarcoidosis Myocardium ,Myocardial perfusion imaging ,03 medical and health sciences ,Cardiomyopathies/diagnostic imaging ,Radionuclide Imaging/standards ,societies ,POSITRON-EMISSION-TOMOGRAPHY ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Fluorodeoxyglucose F18 ,Internal medicine ,Medical imaging ,cardiac MRI ,Late gadolinium enhancement ,Humans ,Radiology, Nuclear Medicine and imaging ,Radionuclide Imaging ,[SDV.IB] Life Sciences [q-bio]/Bioengineering ,Multimodal Imaging/standards ,business.industry ,Magnetic Resonance Imaging/standards ,Reproducibility of Results ,LOW-CARBOHYDRATE-DIET ,Magnetic resonance imaging ,medicine.disease ,n/a OA procedure ,United States ,Cardiac Imaging Techniques/standards ,Cardiac Imaging Techniques ,MYOCARDIAL FDG UPTAKE ,inflammation ,Positron-Emission Tomography ,Position paper ,Nuclear Medicine ,business ,Nuclear medicine ,Tomography, X-Ray Computed - Abstract
International audience; This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with 18F-fluorodeoxyglucose positron emission tomography, radionuclide myocardial perfusion imaging and cardiovascular magnetic resonance imaging for the evaluation and management of patients with known or suspected cardiac sarcoidosis. This position paper will aid in standardizing imaging for cardiac sarcoidosis and may facilitate clinical trials and pooling of multi-centre data on cardiac sarcoidosis. Proposed flow charts for the work up and management of cardiac sarcoidosis are included.
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- 2017
28. Consensus document for the diagnosis of prosthetic joint infections: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)
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Signore, A., Sconfienza, L.M., Borens, O., Glaudemans, AWJM, Cassar-Pullicino, V., Trampuz, A., Winkler, H., Gheysens, O., Vanhoenacker, FMHM, Petrosillo, N., and Jutte, P.C.
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Consensus ,Documentation ,Europe ,Evidence-Based Medicine ,Humans ,Nuclear Medicine ,Prosthesis-Related Infections/diagnosis ,Prosthesis-Related Infections/diagnostic imaging ,Societies, Scientific ,Guideline ,Imaging ,Infection diagnosis ,Prosthetic joint infection - Abstract
For the diagnosis of prosthetic joint infection, real evidence-based guidelines to aid clinicians in choosing the most accurate diagnostic strategy are lacking. To address this need, we performed a multidisciplinary systematic review of relevant nuclear medicine, radiological, orthopaedic, infectious, and microbiological literature to define the diagnostic accuracy of each diagnostic technique and to address and provide evidence-based answers on uniform statements for each topic that was found to be important to develop a commonly agreed upon diagnostic flowchart. The approach used to prepare this set of multidisciplinary guidelines was to define statements of interest and follow the procedure indicated by the Oxford Centre for Evidence-based Medicine (OCEBM).
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- 2019
29. Consensus document for the diagnosis of peripheral bone infection in adults: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)
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Glaudemans, AWJM, Jutte, P.C., Cataldo, M.A., Cassar-Pullicino, V., Gheysens, O., Borens, O., Trampuz, A., Wörtler, K., Petrosillo, N., Winkler, H., Signore, A., and Sconfienza, L.M.
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Adult ,Anti-Bacterial Agents/therapeutic use ,Consensus ,Documentation ,Europe ,Evidence-Based Medicine ,Humans ,Nuclear Medicine ,Osteitis/diagnostic imaging ,Osteitis/drug therapy ,Osteomyelitis/diagnostic imaging ,Osteomyelitis/drug therapy ,Societies, Scientific ,Diagnosis of infection ,Guideline ,Imaging ,Osteitis ,Osteomyelitis ,Peripheral bone infection - Abstract
In adults with a suspicion of peripheral bone infection, evidence-based guidelines in choosing the most accurate diagnostic strategy are lacking. To provide an evidence-based, multidisciplinary consensus document on the diagnostic management of adult patients with PBIs, we performed a systematic review of relevant infectious, microbiological, orthopedic, radiological, and nuclear medicine literature. Delegates from four European societies (European Bone and Joint Infection Society, European Society of Microbiology and Infectious Diseases, European Society or Radiology, and European Association of Nuclear Medicine) defined clinical questions to be addressed, thoroughly reviewed the literature pertinent to each of the questions, and thereby evaluated the diagnostic accuracy of each diagnostic technique. Inclusion of the papers per statement was based on a PICO (Population/problem - Intervention/indicator - Comparator - Outcome) question following the strategy reported by the Oxford Centre for Evidence-based Medicine. For each statement, the level of evidence was graded according to the 2011 review of the Oxford Centre for Evidence-based Medicine. All approved statements were addressed taking into consideration the available diagnostic procedures, patient acceptance, tolerability, complications, and costs in Europe. Finally, a commonly agreed-upon diagnostic flowchart was developed.
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- 2019
30. Cardiac 123I-mIBG scintigraphy as a tool to optimize CRT patient selection
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Verschure, D. O., Poel, E., Frantellizzi, V., De Vincentis, G., Gheysens, O., de Groot, J. R., and H. J. Verberne.
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- 2019
31. How does mechanical dyssynchrony affect the efficiency of the left ventricle?
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Nuyts, J., Unlu, SERKAN, Rega, F., Gheysens, O., Beela, A. S., Duchenne, J., Turco, A., Claus, P., Vunckx, K., and Voigt, J. -U.
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- 2018
32. FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC
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Slart, R. H. J. A., Glaudemans, A. W. J. M., Chareonthaitawee, P., Treglia, G., Besson, F. L., Bley, T. A., Blockmans, D., Boellaard, R., Bucerius, J., Carril, J. M., Chen, W., Cid, M. C., Dagupta, B., Dorbala, S., Gheysens, O., Hyafil, F., Jain, S., Klink, T., van der Laken, C. J., Lomena, F., Massollo, M., Prieto-Gonzalez, S., Luqmani, R., Roivainen, A., Salvarani, C., Saraste, A., Schirmer, M., Verberne, H. J., Versari, A., Voskuyl, A. E., Walter, M. A., Camellino, D., Brouwer, E., Cimmino, M. A., Abidov, A., Agostini, D., Beanlands, R. S., Delgado-Bolton, R. C., Einstein, A. J., Gimelli, A., Miller, E. J., Sciagra, R., and Signore, A.
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musculoskeletal diseases ,medicine.medical_specialty ,Giant Cell Arteritis ,Disease ,Review Article ,DISEASE-ACTIVITY ,030218 nuclear medicine & medical imaging ,Polymyalgia rheumatica ,03 medical and health sciences ,POSITRON-EMISSION-TOMOGRAPHY ,0302 clinical medicine ,GIANT-CELL ARTERITIS ,Fluorodeoxyglucose F18 ,Large vessel vasculitis ,Positron Emission Tomography Computed Tomography ,Imaging procedure ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,030203 arthritis & rheumatology ,FDG-PET/CT(A) ,medicine.diagnostic_test ,business.industry ,ABATACEPT CTLA-4IG ,SEMIQUANTITATIVE ANALYSIS ,TAKAYASU ARTERITIS ,EARLY-DIAGNOSIS ,General Medicine ,medicine.disease ,DOUBLE-BLIND TRIAL ,Functional imaging ,Giant cell arteritis ,Positron emission tomography ,Polymyalgia Rheumatica ,Positron-Emission Tomography ,Public Opinion ,Interest group ,Angiography ,F-18 FDG-PET/CT ,Radiology ,FOLLOW-UP ,business - Abstract
Large vessel vasculitis (LVV) is defined as a disease mainly affecting the large arteries, with two major variants, Takayasu arteritis (TA) and giant cell arteritis (GCA). GCA often coexists with polymyalgia rheumatica (PMR) in the same patient, since both belong to the same disease spectrum. FDG-PET/CT is a functional imaging technique which is an established tool in oncology, and has also demonstrated a role in the field of inflammatory diseases. Functional FDG-PET combined with anatomical CT angiography, FDG-PET/CT(A), may be of synergistic value for optimal diagnosis, monitoring of disease activity, and evaluating damage progression in LVV. There are currently no guidelines regarding PET imaging acquisition for LVV and PMR, even though standardization is of the utmost importance in order to facilitate clinical studies and for daily clinical practice. This work constitutes a joint procedural recommendation on FDG-PET/CT(A) imaging in large vessel vasculitis (LVV) and PMR from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine (EANM), the Cardiovascular Council of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), and the PET Interest Group (PIG), and endorsed by the American Society of Nuclear Cardiology (ASNC). The aim of this joint paper is to provide recommendations and statements, based on the available evidence in the literature and consensus of experts in the field, for patient preparation, and FDG-PET/CT(A) acquisition and interpretation for the diagnosis and follow-up of patients with suspected or diagnosed LVV and/or PMR. This position paper aims to set an internationally accepted standard for FDG-PET/CT(A) imaging and reporting of LVV and PMR. Electronic supplementary material The online version of this article (10.1007/s00259-018-3973-8) contains supplementary material, which is available to authorized users.
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- 2018
33. Subcutaneous leak in a paediatric peritoneal dialysis patient
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De Gersem, R., Knops, N., Goffin, K., Levtchenko, E., and Gheysens, O.
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- 2013
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34. 957 - Predictive factors of positive 68Ga-PSMA PET/CT in patients with PSA recurrence following radical prostatectomy
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Tosco, L., Joniau, S., Witters, M., Battaglia, A., Cromphout, L., Goffin, K., Gheysens, O., Deroose, C., Oyen, R., and Van Laere, K.
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- 2017
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35. The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation.
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Verschure, D O, Poel, E, Vincentis, G De, Frantellizzi, V, Nakajima, K, Gheysens, O, Groot, J R de, and Verberne, H J
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HEART physiology ,HEART radiography ,SYMPATHETIC nervous system physiology ,CARDIAC pacing ,HEART failure ,POSTOPERATIVE period ,RADIONUCLIDE imaging ,PATIENT selection ,BENZENE derivatives - Abstract
Aims Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New York Heart Association (NYHA) functional class. However, one-third of CHF patients does not benefit from CRT. This study evaluated whether
123 I- meta -iodobenzylguanidine (123 I- m IBG) assessed cardiac sympathetic activity could optimize CRT patient selection. Methods and results A total of 78 stable CHF subjects (age 66.8 ± 9.6 years, 73% male, LVEF 25.2 ± 6.7%, QRS duration 153 ± 23 ms, NYHA 2.2 ± 0.7) referred for CRT implantation were enrolled. Subjects underwent123 I- m IBG scintigraphy prior to implantation. Early and late heart-to-mediastinum (H/M) ratio and123 I- m IBG washout were calculated. CRT response was defined as either an increase of LVEF to >35%, any improvement in LVEF of >10%, QRS shortening to <150 ms, or improvement in NYHA class of >1 class. In 33 patients LVEF increased to >35%, QRS decreased <150 ms in 36 patients, and NYHA class decreased in 33 patients. Late H/M ratio and hypertension were independent predictors of LVEF improvement to >35% (P = 0.0014 and P = 0.0149, respectively). In addition, early H/M ratio, LVEF, and absence of diabetes mellitus (DM) were independent predictors for LVEF improvement by >10%. No independent predictors were found for QRS shortening to <150 ms or improvement in NYHA class. Conclusion Early and late H/M ratio were independent predictors of CRT response when improvement of LVEF was used as measure of response. Therefore, cardiac123 I- m IBG scintigraphy may be used as a tool to optimize selection of subjects that might benefit from CRT. [ABSTRACT FROM AUTHOR]- Published
- 2021
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36. Subvalvular geometry and increased sphericity significantly increases papillary muscle contribution to myocardial workload in dilated left ventricles
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Vunckx, K., Voigt, J. U., Gheysens, O., Rega, F., Coudyzer, W., Nuyts, J., Unlu, SERKAN, Pagourelias, E., Duchenne, J., Bezy, S., Turco, A., and Claus, P.
- Published
- 2017
37. Whole-body diffusion-weighted magnetic resonance imaging at 3 Tesla for early assessment of treatment response in non-Hodgkin lymphoma: a pilot study
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Pascal Wolter, Ann Janssens, De Keyzer F, Raymond Oyen, C. Bevernage, De Paepe K, Gheysens O, Vandecaveye, and Gregor Verhoef
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medicine.medical_specialty ,medicine.medical_treatment ,Whole body imaging ,Pilot Projects ,chemotherapy ,Multimodal Imaging ,Humans ,Medicine ,Effective diffusion coefficient ,Whole Body Imaging ,Radiology, Nuclear Medicine and imaging ,Lymph node ,Whole-body imaging ,Chemotherapy ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Lymphoma, Non-Hodgkin ,non-Hodgkin lymphoma ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Lymphoma ,Diffusion Magnetic Resonance Imaging ,Treatment Outcome ,medicine.anatomical_structure ,Oncology ,Positron emission tomography ,Positron-Emission Tomography ,Original Article ,diffusion-weighted magnetic resonance imaging ,Body region ,Radiology ,Tomography, X-Ray Computed ,business ,Nuclear medicine - Abstract
Objective: To evaluate 3 Tesla (T) whole-body diffusion-weighted magnetic resonance imaging (WB DWI) for early treatment assessment in aggressive non-Hodgkin lymphoma (NHL). Methods: Fourteen patients with NHL treated with standard chemotherapy underwent 3-T WB DWI before and 2 and 4 weeks during treatment, using b-values of 0-1000 s/mm from which the apparent diffusion coefficient (ADC) was calculated. Patient follow-up (average 20.3 months, range 15-23 months) was the reference standard. Volume and ADC changes between baseline and 2 weeks (Vratio, ADCratio) and 4 weeks (Vratio, ADCratio) of responding and non-responding lesions (lymph node and organ lesions) were compared using Mann-Whitney U tests. The per patient values of Vratio and ADCratio to predict progression-free survival were determined with a log-rank test. Results: Eight patients showed complete remission and 6 showed tumour progression. The ADCratio and ADCratio differed significantly in lesions showing tumour progression versus complete remission (ADCratio = 4 ± 21% versus 119 ± 68%; ADCratio = 18 ± 61% versus 155 ± 78%; both P < 0.0001); the Vratio and Vratio did not (P > 0.05). Per body region, the ADCratio showed a negative predictive value of 100% and positive predictive value of 86%. Per patient, the ADCratio and ADCratio correlated significantly with progression-free survival (P < 0.05). Conclusion: 3-T WB DWI with ADC quantification may enable early treatment assessment of aggressive NHL. ispartof: Cancer Imaging vol:13 issue:1 pages:53-62 ispartof: location:England status: published
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- 2013
38. Funding Opportunities Include PhD and Postdoctoral Fellowships and Research Grants for Senior Clinical Investigators in Belgium
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Taylor, J., Gheysens, O., De Sutter, Johan, and Cardio-vascular diseases
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NA
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- 2012
39. Dietary saturated fatty acids aggravate pressure overload-induced cardiomyopathy in mice in the absence of cardiac steatosis
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Muthuramu, I., Amin, R., Singh, N., Postnov, A., Gheysens, O., Van Veldhoven, P., and De Geest, B.
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- 2016
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40. Impact of CT-based Attenuation Correction on the Registration Between Dual-gated Cardiac PET and High-Resolution CT.
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Turco, A., Gheysens, O., Nuyts, J., Duchenne, J., Voigt, J. U., Claus, P., and Vunckx, K.
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- *
CARDIAC imaging , *POSITRON emission tomography , *IMAGE reconstruction , *FLUORODEOXYGLUCOSE F18 , *ATTENUATION coefficients - Abstract
A high-resolution CT (HRCT) used as anatomical prior information during PET reconstruction can enhance the quality of a corresponding low-resolution PET image, provided that it is accurately registered to the PET dataset of interest. In this work, the impact of different PET/CT attenuation correction (AC) protocols on the registration between a dual-gated cardiac ^18F-FDG PET image and an HRCT image is investigated. The aim is to explore the impact of AC on PET-to-HRCT registration, and to identify the AC strategy that yields the best alignment between the left-ventricles in the PET and the HRCT images for subsequent partial volume correction. Simulations were performed using XCAT phantoms. Shallow breathing and a regular beating pattern were simulated and both noise-free and noisy data were evaluated. Respiratory motion during the acquisition of the CT used for attenuation correction strongly affected the dual-gated PET reconstructions, resulting in artefacts and quantification errors in the PET image and poor PET-to-HRCT registration accuracy. The blurring introduced by the beating heart, on the other hand, proved to have a negligible effect on PET-CT registration. Dual-gated PET images reconstructed without attenuation correction could be well registered to the HRCT if a good initial alignment between the starting images was provided. A commercially available strategy to deal with an AC CT that is acquired in the wrong respiratory phase was also evaluated, and yielded not only enhanced quantitative accuracy but also accurate PET-to-HRCT registration. The effect of a high level of noise, as present in a dual-gated cardiac PET study, was also investigated. Registrations proved to be sensitive to noise, but noise is not a major limiting factor for PET-to-HRCT registration. A selection of the investigated attenuation correction procedures was also evaluated using cardiac PET/CT data measured in sheep. The PET-to-HRCT registration performance confirmed the XCAT-based predictions. [ABSTRACT FROM PUBLISHER]
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- 2016
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41. Registration between respiratory-gated PET/CT and high-resolution CT with XCAT simulations: Evaluation and optimization for subsequent PVC.
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Turco, A., Nuyts, J., Gheysens, O., Voigt, J.U., Claus, P., and Vunckx, K.
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- 2013
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42. G.P.173: Are current formulas for estimated glomerular filtration rate reliable in children and adolescents with Duchenne muscular dystrophy?
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De Waele, L., Braat, E., Vermeersch, P., Gheysens, O., Levtchenko, E., Pottel, H., Hoste, L., and Goemans, N.
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- 2014
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43. G.P.172: Renal function in children and adolescents with Duchenne muscular dystrophy: a prospective study
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De Waele, L., Braat, E., Vermeersch, P., Gheysens, O., Levtchenko, E., Pottel, H., Hoste, L., and Goemans, N.
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- 2014
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44. 266PD_PR - Sentinel Lymph Node Biopsy for Breast Cancer Treatment During Pregnancy - on Behalf of the International Network of Cancer, Infertility and Pregnancy (Incip) and the German Breast Group (Gbg)
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Han, S.N., Amant, F., Sangalli, C., Loibl, S., Gheysens, O., Lok, C.A.R., Dahl Steffensen, K., Halaska, M.J., Peccatori, F.A., and Gentilini, O.
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- 2014
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45. Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.
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Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, and Herijgers P
- Published
- 2009
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46. Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography.
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Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS, Willmann, Jürgen K, Chen, Kai, Wang, Hui, Paulmurugan, Ramasamy, Rollins, Mark, Cai, Weibo, Wang, David S, and Chen, Ian Y
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- 2008
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47. Validation of anatomy-enhanced cardiac FDG-PET imaging: An ex vivo sheep study.
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Turco, A., Duchenne, J., Nuyts, J., Gheysens, O., Voigt, J.U., Claus, P., and Vunckx, K.
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- 2014
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48. P154 Absolute vs semiquantitative 13N-NH3 myocardial perfusion and 18F-FDG metabolism in non-ischemic patients with LBBB selected for cardiac resynchronization therapy.
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Degtiarova, G, Claus, P, Duchenne, J, Voigt, J-U, Verberne, H J, Schramm, G, Nuyts, J, and Gheysens, O
- Subjects
HEART metabolism ,BUNDLE-branch block ,CARDIAC pacing ,CONFERENCES & conventions ,DEOXY sugars ,PERFUSION ,RADIONUCLIDE imaging ,RADIOPHARMACEUTICALS - Published
- 2019
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49. 75 Evolution of cardiac magnetic resonance findings in patient with asymptomatic cardiac sarcoidosis.
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Degtiarova, G, Gheysens, O, Cleemput, J Van, Wuyts, W, and Bogaert, J
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SARCOIDOSIS diagnosis ,CONFERENCES & conventions ,MAGNETIC resonance imaging ,MYOCARDIUM - Published
- 2019
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50. 333 Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block.
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Larsen, C Kjellstad, Aalen, J M, Stokke, C, Fjeld, J G, Kongsgaard, E, Duchenne, J, Degtiarova, G, Gheysens, O, Voigt, J-U, Smiseth, O A, and Hopp, E
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BLOOD pressure ,BUNDLE-branch block ,CONFERENCES & conventions ,HEART diseases ,HEART ventricles ,MAGNETIC resonance imaging - Published
- 2019
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