1. Nonsurgical Treatment for Localized Hepatocellular Carcinoma
- Author
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Andrew S. Kennedy and Bruno Sangro
- Subjects
Oncology ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Tare weight ,Transarterial embolization ,Stereotactic body radiotherapy ,medicine.medical_treatment ,Selective internal radiation therapy ,External beam radiotherapy ,Antineoplastic Agents ,Transarterial chemoembolization ,Gastrointestinal Cancers (B Czito, Section Editor) ,Gastrointestinal cancer ,Internal medicine ,medicine ,Humans ,Combined Modality Therapy ,Yttrium ,SIRT ,Chemoembolization, Therapeutic ,Radioembolization ,TACE ,Chemotherapy ,Evidence-Based Medicine ,SBRT ,Radiotherapy ,business.industry ,Liver Neoplasms ,TAE ,medicine.disease ,Microspheres ,digestive system diseases ,Radiation therapy ,Hepatocellular carcinoma ,Proton ,Radiology ,business - Abstract
The most common non-surgical approaches for the treatment of localized hepatocellular carcinoma remain hepatic artery-delivered particles laden with chemotherapy (TACE), or radioactive microparticles (TARE). External beam radiotherapy has been an effective option in many parts of the world for selected HCC patients, but now has an expanded role with stereotactic and proton beam technologies. This review focuses on existing evidence and current guidance for utilizing these modalities for localized, but unresectable, non-transplantable HCC patients.x.
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