Search

Your search keyword '"Gargantini, L"' showing total 153 results
Start Over Author "Gargantini, L" Language english
153 results on '"Gargantini, L"'

15. Emerging effects of early environmental factors over genetic background for type diabetes suscetibility: Evidence from a nationwide Italian twin study

Author

Nisticò L, Iafusco D, GalderisiA, Fagnani C, Cotichini R, Toccarelli V, Stazi MA, Cherubini V, Iannilli A, Paparusso AM, Cavallo L, Zecchino C, De Filippo G, Gargantini L, Salardi S, Zucchini S, Maltoni G, Pasquino B, Kaufmann P, Buzi F, Prandi E, Bonfanti R, Nisticò, L, Iafusco, D, Galderisia, Fagnani, C, Cotichini, R, Toccarelli, V, Stazi, Ma, Cherubini, V, Iannilli, A, Paparusso, Am, Cavallo, L, Zecchino, C, De Filippo, G, Gargantini, L, Salardi, S, Zucchini, S, Maltoni, G, Pasquino, B, Kaufmann, P, Buzi, F, Prandi, E, Bonfanti, R, and Et, Al.

Published
2012

16. In vivo purging followed by autotransplant induces long clinical and molecular remission in relapsed/refractory follicular lymphoma patient

Author

Arcaini, L, Montanari, F, Alessandrino, EP, Gargantini, L, Cairoli, R, Tucci, A, Bernasconi, P, Brusamolino, E, Troletti, D, Zoli, V, Bottelli, C, Billio, A, Pomponi, F, Rossi, G, Majolino, I, Morra, E, Lazzarino, M, Arcaini, L, Montanari, F, Alessandrino, E, Gargantini, L, Cairoli, R, Tucci, A, Bernasconi, P, Brusamolino, E, Troletti, D, Zoli, V, Bottelli, C, Billio, A, Pomponi, F, Rossi, G, Majolino, I, Morra, E, and Lazzarino, M

Subjects
Hematology
Published
2007

18. Increasing burden, younger age at onset and worst metabolic control in migrant than in Italian children with type 1 diabetes: An emerging problem in pediatric clinics

Author

Cadario, F1, Cerutti, F, Savastio, S, Rabbone, I, Tumini, S, Bruno, G, Lera, R, Cherubini, V, Bechaz, M, Zucchini, S, Prandi, E, Zattoni, V, Coccioli, S, Frongia, A, La Loggia, A, Lo Presti, D, Citrini, F, Suprani, T, Dedonno, V, Vergerio, A, Banin, P, Toni, S, Piccini, B, Barni, F, Pescamona, M, Cardinale, G, Lombardo, F, Bonfanti, R, Scaramuzza, A, Iughetti, Lorenzo, Franzese, A, Iafusco, D, Guercio Nuzio, S, Abiuso, C, Monciotti, C, Cardella, F, Vanelli, M, Chiari, G, Calcaterra, V, De Giorgi, G, Zanette, G, Marsciani, A, Patera, P, Manca Bitti, M, Delvecchio, M, Trada, M, Aimar, A, Gaiero, A, Tinti, D, Fontana, F, Guerraggio, L, Cauvin, V, Gargantini, L, Salvatoni, A, Trivellin, V, Maffeis, C, Marigliano, M, Arnaldi, C., Cadario, F, Cerutti, F, Savastio, S, Rabbone, I, Tumini, S, Bruno, G, Italian Society of Pediatric, Endocrinology, Diabetology Study, Group, Iafusco, Dario, Italian Society of pediatric Endocrinology and Diabetology Study group, (SIEDP), and Bonfanti, R

Subjects
Male, Age of onset, Children immigration, Environment factors, Type 1 diabetes, Pediatrics, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, TYPE I (INSULIN-DEPENDENT) DIABETES MELLITUS, Disease, Statistics, Nonparametric, Endocrinology, HLA Antigens, Weight loss, Interquartile range, Diabetes mellitus, Prevalence, Internal Medicine, medicine, Humans, Insulin, Genetic Predisposition to Disease, Child, Alleles, Glycemic, Transients and Migrants, Settore MED/38 - Pediatria Generale e Specialistica, business.industry, Case-control study, Infant, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, Italy, Case-Control Studies, Child, Preschool, Female, medicine.symptom, business, Type 1 diabetes Children immigration Age of onset Environment factors
Abstract

To assess burden and clinical features of type 1 diabetes in migrant with respect to Italian children. Prevalent children with type 1 diabetes were identified through a multicenter study, including 46 pediatric outpatients diabetic clinics. A nested case–control study was also performed, comparing features at diabetes onset and after 1 year of insulin treatment in 84 migrants and 75 Italian children with onset in 2011, matched for age and sex. Out of 7,812 children cared for by pediatric diabetologists, 761 (10 %) were migrant and 548 of them were born in Italy. Age at diagnosis was lower in migrants born in Italy (5.1 years, interquartile range (IQR) 2.2–7.7) than in those born in their original countries (7.8 years, IQR 5.3–10.3) and in Italians (9.8 years, IQR 5.9–13.0, p\0.001). At diabetes onset, migrants had lower frequencies of positivities of markers of b-cell autoimmunity (96 vs. 99.5 %, p\0.01), higher values of weight loss (11 vs. 7 %, p\0.01), HbA1c (70 vs. 58 mmol/mol, p\0.001), and insulin requirement (0.70 ± 0.03 vs. 0.63 ± 0.10 UI/kg/die, p = 0.05) and lower levels of 25-OH vitamin D3 (15.0 ± 2.8 vs. 20.8 ± 1.3, p = 0.03). Moreover, they experienced higher frequencies of hospitalizations during the first year of disease (19.2 vs. 2.7 %, p\0.001). Burden of type 1 diabetes in migrant children is increasing in Italy, with younger age at onset and different clinical features than in Italian children. Higher hospitalization rates and poorer glycemic control over the first year underline that approach to diabetes care in migrants needs to be improved.

Published
2014

19. Severe hypoglycemia and ketoacidosis over one year in Italian pediatric population with type 1 diabetes mellitus: a multicenter retrospective observational study

Author

Cherubini, V, Pintaudi, B, Rossi, Mc, Lucisano, G, Pellegrini, F, Chiumello, G, Frongia, Ap, Monciotti, C, Patera, Ip, Toni, S, Zucchini, S, Nicolucci, A, Lera, R, Iannilli, A, Giorgetti, C, Cesaretti, A, Paparusso, Am, Alessandrelli, Mc, Scipione, M, Balsamo, C, Gallo, F, Lo Presti, D, Passanisi, S, Tumini, S, Cipriano, P, Lazzaro, N, Vergerio, A, Banin, P, Lenzi, L, Coccioli, Ms, D'Annunzio, G, Bruzzese, M, Lombardo, F, Salzano, G, Bonfanti, R, Frontino, G, Battaglino, R, Iughetti, Lorenzo, Predieri, Barbara, Cadario, F, Savastio, S, Zabadneh, N, Zanella, C, Mozzo, E, Tiozzo, S, Benevento, D, Calcaterra, V, Larizza, D, Delvecchio, M, Trada, M, Rabbone, I, Sicignano, S, Cauvin, V, Franceschi, R, Gargantini, L, Pennati, C, Bianchi, G, Salvatoni, A, Maffeis, C, Marigliano, M, Sabbion, A, Arnaldi, C, Tosini, D, Tossi, Mc, Valentini, M, D'Alonzo, D, Pirozzoli, C, Di Nardo, B, Memmo, R, and Cianci, A.

Subjects
Male, medicine.medical_specialty, Children and adolescents, endocrine system diseases, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Insulin, Isophane, Medicine (miscellaneous), NPH insulin, TYPE I (INSULIN-DEPENDENT) DIABETES MELLITUS, Internal medicine, Diabetes mellitus, medicine, Humans, Hypoglycemic Agents, Insulin, Child, Retrospective Studies, Glycated Hemoglobin, Type 1 diabetes, Severe hypoglycemia, Nutrition and Dietetics, business.industry, Incidence (epidemiology), Incidence, Infant, Retrospective cohort study, Diabetes ketoacidosis, Ketosis, medicine.disease, Hypoglycemia, Ketoacidosis, Surgery, Diabetes Mellitus, Type 1, Italy, Child, Preschool, Regular insulin, Female, Cardiology and Cardiovascular Medicine, business
Abstract

Background and aims: Evaluation of incidence and correlates of severe hypoglycemia (SH) and diabetes ketoacidosis (DKA) in children and adolescents with T1DM. Methods and results: Retrospective study conducted in 29 diabetes centers from November 2011 to April 2012. The incidence of SH and DKA episodes and their correlates were assessed through a questionnaire administered to parents of patients aged 0e18 years. Incidence rates and incident rate ratios (IRRs) were estimated through multivariate Poisson regression analysis and multilevel analysis. Overall, 2025 patients were included (age 12.4 � 3.8 years; 53% males; diabetes dura- tion 5.6 � 3.5 years; HbA1c 7.9 � 1.1%). The incidence of SH and DKA were of 7.7 and 2.4 events/ 100 py, respectively. The risk of SH was higher in females (IRR Z 1.44; 95%CI 1.04e1.99), in pa- tients using rapid acting analogues as compared to regular insulin (IRR Z 1.48; 95%CI 0.97e2.26) and lower for patients using long acting analogues as compared to NPH insulin (IRR Z 0.40; 95% CI 0.19e0.85). No correlations were found between SH and HbA1c levels. The risk of DKA was higher in patients using rapid acting analogues (IRR Z 4.25; 95%CI 1.01e17.86) and increased with insulin units needed (IRR Z 7.66; 95%CI 2.83e20.74) and HbA1c levels (IRR Z 1.63; 95% CI 1.36e1.95). Mother' sa ge was inversely associated with the risk of both SH (IRRZ 0.95; 95%CI 0.92e0.98) and DKA (IRR Z 0.94; 95%CI 0.88e0.99). When accounting for center effect, the risk of SH associated with the use of rapid acting insulin analogues was attenuated (IRR Z 1.48; 95%CI 0.97e2.26); 33% and 16% of the residual variance in SH and DKA risk was ex- plained by center effect. Conclusion: The risk of SH and DKA is mainly associated with treatment modalities and strongly depends on the practice of specialist centers.

Published
2014

30. Complications of ABO-incompatible Bone Marrow Transplantation (BMT)

Author

Santoleri, L, Cairoli, R, Marenco, P, Gargantini, L, Pezzetti, L, Intropido, L, Morra, E, Santoleri, L, Cairoli, R, Marenco, P, Gargantini, L, Pezzetti, L, Intropido, L, and Morra, E

Subjects
Transplantation, Biophysic, Oncology, Immunology, Hematology
Published
2001

31. Emerging effects of early environmental factors over genetic background for type 1 diabetes susceptibility: Evidence from a nationwide Italian twin study

Author

Nisticò, L, Iafusco, D, Galderisi, A, Fagnani, C, Cotichini, R, Toccaceli, V, Stazi, Ma, Study Group on Diabetes of the Italian Society of Pediatric Endocrinology, Collaborators: Cherubini V, D. i. a. b. e. t. o. l. o. g. y., Iannilli, A, Paparusso, Am, Cavallo, L, Zecchino, C, de Filippo, G, Gargantini, L, Salardi, S, Zucchini, S, Maltoni, G, Pasquino, B, Kaufmann, P, Buzi, F, Prandi, E, Gallo, F, Cicchetti, M, Castaldo, E, Citriniti, F, Chiarelli, F, Tumini, S, Di Stefano, A, Sperlì, D, De Marco, R, Banin, P, Toni, S, Lenzi, L, Del Vecchio, M, Lorini, R, D'Annunzio, G, Ingletto, D, Scaramuzza, A, Zuccotti, Gv, Chiumello, G, Meschi, F, Bonfanti, R, Frontino, G, de Luca, F, Lombardo, F, Salzano, G, Iughetti, L, Franzese, A, Buono, P, De Simone, I, Prisco, F, Cocca, A, Cadario, F, Monciotti, Cm, Savio, V, Cardella, F, Vanelli, M, Chiari, G, Errico, K, Iovane, B, Calcaterra, V, Citro, F, Cantoni, S, Marsciani, A, Cappa, M, Patera, Pi, Schiaffini, R, Sulli, N, Spoletini, M, Cerutti, Franco, Rabbone, I, Sicignano, S, Cauvin, V, Bellizzi, M, Tonini, G, Faleschini, E, Salvatoni, A, Pinelli, L, Maffeis, C, Contreas, G., Nisticò, L, Iafusco, D, Galderisi, A, Fagnani, C, Cotichini, R, Toccaceli, V, Stazi, Ma, and the Study Group on Diabetes of the Italian Society of Pediatric Endocrinology and, Diabetology

Subjects
Adult, Male, Endocrinology, Diabetes and Metabolism, Biochemistry, Endocrinology, Clinical Biochemistry, Biochemistry (medical), medicine.medical_specialty, Adolescent, Child, Child, Preschool, Diabetes Mellitus, Type 1, Environment, Female, Humans, Infant, Kaplan-Meier Estimate, Twins, Dizygotic, Twins, Monozygotic, Genetic Predisposition to Disease, type 1 diabetes, Concordance, Population, Twins, Context (language use), Monozygotic, Internal medicine, Diabetes mellitus, Diabetes Mellitus, Dizygotic, medicine, Preschool, education, Type 1 diabetes, education.field_of_study, business.industry, medicine.disease, Twin study, Zygosity, Diabetes and Metabolism, Cohort, Environmental Exposures, business, Type 1
Abstract

Context:The incidence of type 1 diabetes has been increasing over time.Objective:We estimated the genetic and environmental components of type 1 diabetes susceptibility in a twin cohort of recent-onset cases to explore the sources of changing disease epidemiology.Design:We linked the population-based Italian Twin Registry with 14803 type 1 diabetes records from 36 pediatric diabetes care centers throughout Italy, except Sardinia, and identified 173 diabetic twins. Patients were positive for at least one autoantibody to islet cell, glutamate decarboxylase, tyrosine phosphatase, insulin, or zinc transporter 8 and were insulin dependent since their diagnosis. Zygosity was determined by DNA genotyping or by questionnaire.Outcome Measures:We estimated proband-wise concordance, cotwin recurrence risk with Kaplan-Meier method, and genetic and environmental proportions of susceptibility variance by structural equation models.Results:We recruited 104 diabetic twins (53 males) from 88 pairs (34 monozygotic, 54 dizygotic) and one triplet. The mean age at diagnosis was 8.1 yr (range 1.1-20.5 yr), and the median year of diagnosis was 2002. Proband-wise concordances were 45.5 and 16.4% in monozygotic and dizygotic pairs (P = 0.01). Recurrence risks in monozygotic and dizygotic cotwins were 37 and 12% after 10 yr from the proband's diagnosis (P = 0.005). Genetic contribution to type 1 diabetes susceptibility was 40% (95% confidence interval 8-78), and the shared and individual-specific environmental components were 51% (14-77) and 9% (4-19), respectively.Conclusions:In addition to the moderate genetic effects on type 1 diabetes susceptibility, our results draw attention to the substantial shared environmental effects, suggesting that exposures in fetal or early postnatal life may contribute to the increasing incidence of the disease.

Published
2012

33. Growth hormone secretory pattern in non-obese children and adolescents with Prader-Willi syndrome

Author

Grugni G, Crinò A, Pagani S, Cristina MEAZZA, Buzi F, De Toni T, Gargantini L, Pilotta A, Gb, Pozzan, Radetti G, Ragusa L, Salvatoni A, Sartorio A, Bozzola M, Genetic Obesity Study Group, and Italian Society of Pediatric Endocrinology and Diabetology

Subjects
Male, medicine.medical_specialty, Adolescent, Lymphoma, Arginine, Endocrinology, Diabetes and Metabolism, Fluoroimmunoassay, Growth hormone, Body Mass Index, Endocrinology, Non obese, Cell Line, Tumor, Internal medicine, medicine, Humans, Obesity, Insulin-Like Growth Factor I, Child, Cell Proliferation, Human Growth Hormone, business.industry, Healthy subjects, Reproducibility of Results, nutritional and metabolic diseases, medicine.disease, Control subjects, Growth hormone secretion, Prolactin, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, Secretory Rate, business, Prader-Willi Syndrome, Body mass index
Abstract

The aetiology of impaired growth hormone (GH) secretion in Prader-Willi syndrome (PWS) remains controversial due to the common occurrence of obesity. To further clarify whether suboptimal GH secretion in PWS is an artefact of excess weight, we evaluated both GH immunological activity and GH bioactivity after arginine administration in 23 non-obese PWS patients [seven females, aged 6.9 +/- 0.9 years, body mass index (BMI) SDS 0.63 +/- 0.26], in comparison with a control group of 32 healthy subjects, matched for age, gender and BMI (10 females, aged 7.9 +/- 0.3 years, BMI SDS 0.21 +/- 0.20). Serum GH concentration was measured with a time-resolved immunofluorometric assay (IFMA), while GH bioactivity was evaluated by the Nb2 cell bioassay. Serum IGF-I concentrations were measured by double-antibody RIA. GH mean peak after pharmacological stimulation was significantly lower in PWS individuals compared with controls when measured either by IFMA (6.05 +/- 1.23 microg/L vs. 23.7 +/- 1.06 microg/L, p < 0.0001) or by Nb2 (6.87 +/- 0.55 microg/L vs. 12.88 +/- 0.19 microg/L, p < 0.0001). Analysis of integrated GH secretion (AUC) confirmed that the PWS group differed significantly from the control subjects (387.9 +/- 76.1 microg/L/h vs. 1498.1 +/- 56.2 microg/L/h, p < 0.0001); the same result was obtained when the GH rise after arginine administration was expressed as nAUC (278.2 +/- 53.3 microg/L/h vs. 1443.6 +/- 52.5 microg/L/h, p < 0.0001). PWS patients had an IGF-I SDS significantly lower than those found in control subjects (p < 0.0001). Subnormal IGF-I values were present in 19 PWS individuals (82.6%) and two healthy controls (6.2%). These findings are in agreement with the hypothesis that a complex derangement of hypothalamus-pituitary axis occurs in PWS.

Published
2011

34. Permanent diabetes during the first year of life: multiple gene screening in 54 patients

Author

Russo, L, Iafusco, D, Brescianini, S, Nocerino, V, Bizzarri, C, Toni, S, Cerutti, F, Monciotti, C, Pesavento, R, Iughetti, L, Bernanrdini, L, Bonfanti, R, Gargantini, L, Vanelli, M, AGUILAR BRYAN, L, Stazi, Ma, Grasso, V, Colombo, C, Barbetti, F, the EARLY DIABETES STUDY GROUP LERA, R, Cherubini, V, Fifi, Ar, Torelli, C, Frezza, E, Cavallo, L, Zucchini, S, Pasquino, B, Kaufmann, P, Frongia, P, Zedda, N, Ripoli, C, LA LOGGIA, A, LO PRESTI, D, Pocecco, M, Chiarelli, F, Tumini, S, DEL DONNO, M, DE MARCO MR, Lenzi, L, Lorini, R, D'Annunzio, G, Lombardo, F, Meschi, F, Franzese, A, Buono, P, Prisco, F, Cadario, F, Cardella, F, Calcaterra, V, DE GIORGI, G, Federico, Giovanni, Cappa, M, Sulli, N, MANCA BITTI ML, Delvecchio, M, Cotellessa, M, Rabbone, I, Cauvin, V, Bellizzi, M, Tonini, G, Salvatoni, A, and Pinelli, L.

Published
2011

36. The Italian National Survey for Prader-Willi syndrome: an epidemiologic study

Author

Grugni, G, Crinò, A, Bosio, L, Corrias, A, Cuttini, M, DE TONI, T, DI BATTISTA, E, Franzese, A, Gargantini, L, Greggio, N, Iughetti, Lorenzo, Livieri, C, Naselli, A, Pagano, C, Pozzan, G, Ragusa, L, Salvatoni, A, Trifirò, G, Beccaria, L, Bellizzi, M, Bellone, J, Brunani, A, Cappa, M, Caselli, G, Cerioni, V, Delvecchio, M, Giardino, D, Iannì, F, Memo, L, Pilotta, A, Pomara, C, Radetti, G, Sacco, M, Sanzari, A, Sartorio, A, Tonini, G, Vettor, R, Zaglia, F, Chiumello, G, and GENETIC OBESITY STUDY GROUP OF ITALIAN SOCIETY OF PEDIATRIC ENDOCRINOLOGY AND DIABETOLOGY ISPED

Subjects
Adult, Male, obesity, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Pediatrics, Epidemiologic study, Adolescent, Body Mass Index, Chromosome 15, death, Internal medicine, Epidemiology, Genetics, medicine, Humans, Obesity, Child, Genetics (clinical), In Situ Hybridization, Fluorescence, Cause of death, Chromosomes, Human, Pair 15, business.industry, Mortality rate, Prader-Willi syndrome, GH therapy, nutritional and metabolic diseases, Respiratory infection, Infant, Middle Aged, medicine.disease, Death, Endocrinology, Italy, Child, Preschool, Growth Hormone, Female, Risk of death, business, Prader-Willi Syndrome, Prader-Willi syndrome, obesity, GH therapy, death
Abstract

Twenty-five medical centers and the Prader–Willi Syndrome (PWS) Association collaborated on a study which attempted to identify all people with genetically confirmed diagnosis of PWS living in Italy. Investigators of the participating centers contacted PWS subjects and/or their family, filled in a specially developed form with the required data and forwarded this information by email. The study identified 425 subjects (209 males and 216 females, between the ages of 0.4–46.7). Two hundred thirty-eight patients had del15, 104 had UPD15, 4 demonstrated a translocation affecting chromosome 15 and 79 showed a positive methylation test. There were fewer subjects found over the age of 35, probably due to the low rate of identification of older PWS patients as well as the high mortality rate. There were a greater number of male children and adolescents with PWS whilst, amongst adults, there were more females. As expected, the majority of subjects with PWS were obese, especially in adult life. Nevertheless, it is noteworthy that 26% of patients aged between 6 and 17 were normal weight. A total of 212 subjects had received GH treatment, of which 141 were still receiving therapy, while the remaining 71 had stopped. In children and adolescents (233 cases), 89 subjects had never undergone GH therapy. Eighteen PWS patients had died in the past 20 years. Obesity-related cardiovascular and respiratory diseases were the cause of death, both during childhood and after 18 years of age. Three children died suddenly whilst undergoing GH therapy. Respiratory infection and cardiac illness were the causes of death in two cases. There was no definitive cause of death found in the third case. Overall, there was no increase in number of deaths during GH treatment, suggesting that GH administration in patients with PWS, as a group, does not increase the risk of death. © 2008 Wiley-Liss, Inc.

Published
2008

38. Prevalence of obesity in children and adolescents with Prader-Willi sindrome

Author

Grugni, G., Crinò, A., Bosio, L., Corrias, A., De Toni T, T., Di Battista, E., Franzese, A., Gargantini, L., Greggio, N., Iughetti, Lorenzo, Livieri, C., Naselli, A., Pozzan, G., Ragusa, L., Salvatoni, A., Sartorio, A., Trifirò, G., and Chiumello, G.

Subjects
Prader-Willi syndrome
Published
2007

39. GH therapy and body mass index in Prader-Willi syndrome

Author

Grugni, G., Bosio, L., Cappa, M., Corrias, A., Delvecchio, M., Di Battista, E., Franzese, A., Gargantini, L., Lorenzo Iughetti, Pozzan, C., Radetti, G., Ragusa, L., Salvatoni, A., Sanzari, A., Sartorio, A., and Crino, A.

Published
2005

42. Death in people with Prader-Willi Syndrome: A national Survey

Author

Grugni, G., Corrias, A., Bellone, J., Bosio, L., Cerioni, V., Dekvecchio, M., Detoni, T., Di Battista, E., Gargantini, L., Iughetti, Lorenzo, Livieri, C., Naselli, A., Pilotta, A., Pozzan, G., Ragusa, L., Sacco, M., Salvatoni, A., Sanzari, A., Sartorio, A., Trifirò, G., Aimaretti, G., and Crinò, A.

Subjects
Prader-Willi Syndrome
Published
2004

44. Role of Mycoplasma pneumoniae and Chlamydia pneumoniae in children with community-acquired lower respiratory tract infections

Author

Principi, N., Esposito, S., Blasi, F., Allegra, L., Longhi, R., Grasso, R. M., Vaccaro, R., Troiani, S., Tancredi, F., Tarallo, L., Gargantini, L., Cazzaniga, P., Titone, L., Cascio, A., Zannino, L., Navone, C., Debbia, C., Nespoli, L., Ossola, E., Schettini, F., Rigillo, N., Amendola, F., Mappa, L., Bona, G., Ronchi, B., Bernasconi, S., Iughetti, Lorenzo, Cocuzza, S., Raggi, M., Barberi, I., Lombardo, G., Gitto, S., Sirchia, T., Volpato, S., Voghenzi, A., Caramia, G., Ruffini, E., Cordelli, F., Brutti, R., Santovito, S., Catania, S., and Ajassa, C.

Subjects
Male, Microbiology (medical), Acute Disease, Pneumonia, Mycoplasma, Humans, Child, Mycoplasma pneumoniae, Preschool, Anti-Bacterial Agents, Prospective Studies, Respiratory Tract Infections, Chlamydia Infections, Treatment Outcome, Community-Acquired Infections, Adolescent, Chlamydophila pneumoniae, Time Factors, Female, Mycoplasmataceae, medicine.disease_cause, Lower respiratory tract infection, Pneumonia, Mycoplasma, medicine, Chlamydiaceae, Chlamydia, Respiratory tract infections, biology, business.industry, Chlamiydia pneumoniae, medicine.disease, biology.organism_classification, respiratory tract diseases, Infectious Diseases, Child, Preschool, Immunology, business
Abstract

In order to evaluate the role of Mycoplasma pneumoniae and Chlamydia pneumoniae, we studied 613 children aged 2-14 years who were hospitalized for community-acquired lower respiratory tract infections (LRTIs). The patients were enrolled in the study by 21 centers in different regions of Italy from May 1998 through April 1999. Paired serum samples were obtained on admission and after 4-6 weeks to assay the titers of M. pneumoniae and C. pneumoniae antibodies. Nasopharyngeal aspirates for the detection of M. pneumoniae and C. pneumoniae were obtained on admission. Acute M. pneumoniae infections in 210 patients (34.3%) and acute C. pneumoniae infections in 87 (14.1%) were diagnosed. Fifteen of the 18 children with M. pneumoniae and/or C. pneumoniae infections whose treatments were considered clinical failures 4-6 weeks after enrollment had not been treated with macrolides. Our study confirms that M. pneumoniae and/or C. pneumoniae plays a significant role in community-acquired LRTIs in children of all ages and that such infections have a more complicated course when not treated with adequate antimicrobial agents.

Published
2001

46. ESSENTIAL THROMBOCYTHAEMIA:PROGNOSTIC FACTORS IN THE ITALIANSERIES OF TWO THOUSAND PATIENTS

Author

Gugliotta, L., Lazzarino, M., Marchioli, R., Ambrosetti, A., Baravelli, S., Bazzan, M., Cacciola, E., Calori, R., CIOCCA VASINO, A., DE VIVO, A., Fiacchini, M., Finazzi, G., Gargantini, L., Grossi, A., Iannaccaro, P. G., Leva, T., Magrini, U., Marfisi, M. R., Martinelli, V., Mazzucconi, M. G., Morelli, A., Novarino, A., Palmieri, F., Pogliani, E., Radaelli, F., Randi, L., REGE CAMBRIN, G., Ronco, F., Ruggeri, M., Rupoli, S., Russo, D., Sacchi, Stefano, Valdrè, L., Vianelli, N., Rodeghiero, F., Barbui, T., and Tura, S.

Subjects
nd
Published
1999

48. The role of UIE in the diagnosis of neonatal hyperthyrotropinaemia due to topical iodine treatment

Author

Rapa, A, Chiorboli, E, Corbetta, C, Sacco, F, Zaffaroni, M, Cappa, M, Cassio, A, Cavallo, L., Cigolotti, Ac, Desanctis, C, Fabbrizi, E, Frisone, F, Gallina, R, Gargantini, L, Giaretto, C, Larizza, D, Morganti, G, Moschini, L, Pagliano, L, Perona, A, Pezzati, M, Rondanini, Gf, Rusconi, R, Saggese, G, Salvatoni, A, Silvestro, Leandra, Spada, A, Tonini, G, Torresani, Pi, Trifiro, G, Weber, G, Zannino, L, and Bona, Gianni

Published
1996

50. Urinary iodine excretion (UIE) screening in newborn exposed to iodine-containing antiseptic

Author

Rapa, A, Chiorboli, E, Corbetta, C, Sacco, F, Bona, Gianni, Silvestro, Leandra, Zaffaroni, M, Cappa, M, Cassio, A, Cavallo, L., Cigolotti, Ac, Desanctis, C, Fabbrizi, E, Frisone, F, Gallina, R, Gargantini, L, Giaretto, C, Larizza, D, Morganti, G, Moschini, L, Pagliano, L, Perona, A, Pezzati, M, Rondanini, Gf, Rusconi, R, Saggese, G, Salvatoni, A, Spada, A, Tonini, G, Torresani, Pi, Trifiro, G, Weber, G, and Zannino, L.

Published
1996

Catalog

Books, media, physical & digital resources
See catalog results