41 results on '"García-Fuentes, Miguel"'
Search Results
2. To Examine Appropriate Deep-retrofit Practice using Simulation Results in an EU-funded Urban Regeneration Project
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Cui, Jia Michelle, Ianakiev, Anton, and García-Fuentes, Miguel Á.
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- 2017
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3. European Cities Characterization as Basis towards the Replication of a Smart and Sustainable Urban Regeneration Model
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García-Fuentes, Miguel Á., Quijano, Ana, de Torre, Cristina, García, Rubén, Compere, Philippe, Degard, Christelle, and Tomé, Isabel
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- 2017
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4. Methylenetetrahydrofolate Reductase 677CT Polymorphism and Cobalamin, Folate, and Homocysteine Status in Spanish Adolescents
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Al-Tahan, Jasmin, Sola, Ricardo, Ruiz, Jonatan R., Breidenassel, Christina, García-Fuentes, Miguel, Moreno, Luis A., Castillo, Manuel, Pietrzik, Klaus, and González-Gross, Marcela
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- 2008
5. Cardiorespiratory Fitness is Associated with a Favorable Lipid Profile Independent of Abdominal Fat in Male Adolescents: 10:30AM–10:45AM: 611
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Ortega, Francisco B., Ruiz, Jonatan R., Castillo, Manuel J., Moreno, Luis A., Wärnberg, Julia, Tresaco, Beatriz, González-Gross, Marcela, Pérez, Fátima, García-Fuentes, Miguel, and Gutiérrez, Ángel
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- 2006
6. Apolipoprotein C-III and E Polymorphisms and Cardiovascular Syndrome, Hyperlipidemia, and Insulin Resistance in Renal Transplantation
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Rodrigo, Emilio, González-Lamuño, Domingo, Ruiz, Juan Carlos, Fernández-Fresnedo, Gema, Isla, Débora, González-Cotorruelo, Julio, Zubimendi, José Antonio, De Francisco, Angel Luis Martín, García-Fuentes, Miguel, and Arias, Manuel
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- 2002
7. Report on OptEEmAL Platform Demonstration in the Demo Cases
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Pousse, Maxime, Toral, Susana Martin, Diaz, Sonia Alvarez, García-Fuentes, Miguel Á, Serna, Victor, Alegria, Juan Pedrero, Uribarri Serrano, El-Ridouane, Hassan, De Tommasi, Luciano, Martinez, Iker, Dalaryd, Elin, and Mattedi, Micol
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- 2019
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8. Nutrition and physical activity programs for obesity treatment (PRONAF study): methodological approach of the project
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Zapico Augusto G, Benito Pedro J, González-Gross Marcela, Peinado Ana B, Morencos Esther, Romero Blanca, Rojo-Tirado Miguel A, Cupeiro Rocio, Szendrei Barbara, Butragueño Javier, Bermejo Maite, Alvarez-Sánchez María, García-Fuentes Miguel, Gómez-Candela Carmen, Bermejo Laura M, Fernandez-Fernandez Ceila, and Calderón Francisco J
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Overweight ,Obesity ,Caloric restriction ,Exercise ,Weight loss ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background At present, scientific consensus exists on the multifactorial etiopatogenia of obesity. Both professionals and researchers agree that treatment must also have a multifactorial approach, including diet, physical activity, pharmacology and/or surgical treatment. These two last ones should be reserved for those cases of morbid obesities or in case of failure of the previous ones. The aim of the PRONAF study is to determine what type of exercise combined with caloric restriction is the most appropriate to be included in overweigth and obesity intervention programs, and the aim of this paper is to describe the design and the evaluation methods used to carry out the PRONAF study. Methods/design One-hundred nineteen overweight (46 males) and 120 obese (61 males) subjects aged 18–50 years were randomly assigned to a strength training group, an endurance training group, a combined strength + endurance training group or a diet and physical activity recommendations group. The intervention period was 22 weeks (in all cases 3 times/wk of training for 22 weeks and 2 weeks for pre and post evaluation). All subjects followed a hypocaloric diet (25-30% less energy intake than the daily energy expenditure estimated by accelerometry). 29–34% of the total energy intake came from fat, 14–20% from protein, and 50–55% from carbohydrates. The mayor outcome variables assesed were, biochemical and inflamatory markers, body composition, energy balance, physical fitness, nutritional habits, genetic profile and quality of life. 180 (75.3%) subjects finished the study, with a dropout rate of 24.7%. Dropout reasons included: personal reasons 17 (28.8%), low adherence to exercise 3 (5.1%), low adherence to diet 6 (10.2%), job change 6 (10.2%), and lost interest 27 (45.8%). Discussion Feasibility of the study has been proven, with a low dropout rate which corresponds to the estimated sample size. Transfer of knowledge is foreseen as a spin-off, in order that overweight and obese subjects can benefit from the results. The aim is to transfer it to sports centres. Effectiveness on individual health-related parameter in order to determine the most effective training programme will be analysed in forthcoming publications. Trial registration ClinicalTrials.gov NCT01116856
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- 2012
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9. Cryoglobulinaemia In Henoch-SchöNlein Purpura
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Garcia-Fuentes, Miguel, Chantler, Cyril, and Williams, D. Gwyn
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- 1977
10. Body composition changes during a multidisciplinary treatmentprogramme in overweight adolescents: EVASYON Study
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Miguel Etayo, Pilar de, Moreno, Luis A., Santabárbara, Javier, Bueno, Gloria, Martín Matillas, Miguel, Zapatera, Belén, Azcona San Julián, Cristina, Martí, Amelia, Campoy, Cristina, Marcos Sánchez, Ascensión, Garagorri, Jesús M., Redondo Figuero, Carlos, García Fuentes, Miguel, Rufino Rivas, Pedro Manuel de, González-Lamuño Leguina, Domingo, Amigo Lanza, María Teresa, Sanz Giménez-Rico, Juan Ramón, and Universidad de Cantabria
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Programas para la pérdida de peso ,Absorciometría dual de rayos X ,Weight loss programs ,Análisis de intención de tratar ,Dual-energy X-Ray Absorptiometry ,Adolescents ,Body composition ,Adolescentes ,Composición corporal ,Intention to treat analysis - Abstract
Introduction: the main objectives of weight-loss interventions are to decrease fat mass while maintaining fatfree mass. Objective: our aim was to address effectiveness body composition changes in overweight adolescents assessed by different body composition methods following an obesity intervention programme. Material and methods: the life-style intervention was multi-disciplinary, with 13 months follow-up. Participants were 13-to-16 year-old overweight, or obese, Spanish adolescents. The adolescents (n = 156; 54.8% females) had body composition measured with anthropometry, dual-energy X-ray absorptiometry and air-displacement plethysmography. All measurements were made at baseline, and after 2- and 13-months. Repeated measures analysis of covariance to compare mean anthropometric changes over time and the Bonferroni correction were applied. Imputation of anthropometric measures was performed. Results: a high significant decrease in fat mass index was achieved in males after 2-and 13-months of intervention as measured by anthropometry (1.16 and 1.56 kg / m2, respectively), X-ray absorptiometry (1.51 and 1.91 kg / m2) and plethysmography (2.13 and 2.44 kg/m2). Moreover, a short and long-term maintenance of fat-and fat-free mass index was observed by X-ray absorptiometry in females (0.94 and 0.68 kg/m2). Introducción: el principal objetivo de las intervenciones de pérdida de peso es disminuir la masa grasa manteniendo la masa libre de grasa. Objetivo: evaluar la efectividad de una intervención multidisciplinar en la composición corporal de adolescentes con sobrepeso, evaluados mediante diferentes métodos de composición corporal. Material y métodos: la intervención fue multidisciplinar sobre el estilo de vida, aplicada durante 13 meses. Los participantes eran adolescentes entre 13 y 16 años con sobrepeso y obesidad. Los adolescentes (n = 156; 54,8% mujeres) fueron evaluados mediante antropometría, absorciometría dual de rayos X y pletismografía por desplazamiento de aire. Todas las mediciones se realizaron al inicio, a los 2 y a los 13 meses. Se aplicaron análisis de la covarianza de medidas repetidas y la corrección de Bonferroni. Se realizó la imputación de las medidas antropométricas. Resultados: se logró una alta disminución significativa en el índice de masa grasa en los hombres después de 2 y 13 meses de intervención, según antropometría (1,16 y 1,56 kg/m2, respectivamente), absorciometría de rayos X (1,51 y 1,91 kg/m2) y pletismografía (2,13 y 2,44 kg/m2). Por otra parte, el mantenimiento a corto y largo plazo de la grasa y libre de grasa en el índice de masa fue observado por absorciometría de rayos X en las mujeres (0,94 y 0,68 kg/m2).
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- 2015
11. Telomere length as a biomarker for adiposity changes after a multidisciplinary intervention in overweight/obese adolescents: The EVASYON study
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García Calzón, Sonia, Moleres, Adriana, Marcos Sánchez, Ascensión, Campoy, Cristina, Moreno, Luis A., Azcona Sanjulián, M. Cristina, Martínez González, Miguel A., Martínez, J. Alfredo, Zalba Goñi, Guillermo, Marti, Amelia, Redondo Figuero, Carlos, García Fuentes, Miguel, Rufino Rivas, Pedro Manuel de, González-Lamuño Leguina, Domingo, Amigo Lanza, María Teresa, Lanza, R., Noriega Borge, María José, and Universidad de Cantabria
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Male ,Weight loss ,Epidemiology ,Overweight ,Adolescents ,Pediatrics ,Childhood obesity ,Adiposity ,Multidisciplinary ,Anthropometry ,Chromosome Biology ,Child Health ,Genomics ,Telomere ,Polymerase chain reaction ,Weight Reduction Programs ,Telomeres ,Biomarker (medicine) ,Medicine ,Female ,Public Health ,medicine.symptom ,Research Article ,medicine.medical_specialty ,Adolescent ,Diet, Reducing ,Science ,Context (language use) ,Real-Time Polymerase Chain Reaction ,Adolescent Medicine ,Internal medicine ,medicine ,Humans ,Obesity ,Biology ,Nutrition ,DNA Primers ,Clinical Genetics ,business.industry ,Personalized Medicine ,Body weight ,medicine.disease ,Biomarker Epidemiology ,Physical therapy ,Linear Models ,business ,Body mass index ,Biomarkers - Abstract
[Context] Telomeres are biomarkers of biological aging. Shorter telomeres have been associated with increased adiposity in adults. However, this relationship remains unclear in children and adolescents. [Objective] To evaluate the association between telomere length (TL) and adiposity markers in overweight/obese adolescents after an intensive program. We hypothesize that greater TL at baseline would predict a better response to a weight loss treatment. Design, Setting, Patients and Intervention The EVASYON is a multidisciplinary treatment program for adolescents with overweight and obesity that is aimed at applying the intervention to all possibly involved areas of the individual, such as dietary habits, physical activity and cognitive and psychological profiles. Seventy-four participants (36 males, 38 females, 12–16 yr) were enrolled in the intervention program: 2 months of an energy-restricted diet and a follow-up period (6 months). [Main Outcome] TL was measured by quantitative real-time polymerase chain reaction at baseline and after 2 months; meanwhile, anthropometric variables were also assessed after 6 months of follow-up. [Results] TL lengthened in participants during the intensive period (+1.9±1.0, p, Research relating to this work was funded by grants from the Health Research Fund from the Carlos III Health Institute from Ministry of Health and Consumption, Fondo de Investigación Sanitaria (FIS; PI051579, PI051080) for the EVASYON project; Línea Especial, Nutrición y Obesidad (University of Navarra); Spanish Ministry of Science and Innovation (MICINN) [SAF2010-20367]; Carlos III Health Institute [Centro de Investigación Biomédica en Red (CIBER) project, CB06/03/1017], and RETICS network. The scholarship to S. García-Calzón from the FPU ‘Formación de Profesorado Universitario’ from the Spanish Ministry is fully acknowledged.
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- 2015
12. An Evaluation Framework to Support Optimisation of Scenarios for Energy Efficient Retrofitting of Buildings at the District Level.
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García-Fuentes, Miguel Á., Serna, Víctor, Hernández, Gema, and Meiss, Alberto
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RETROFITTING of buildings ,FOSSIL fuel power plants ,FOSSIL fuels ,OFFICE buildings - Abstract
Featured Application: Design of energy-efficient retrofitting projects of buildings at the district scale. Energy-efficient retrofitting of buildings has become essential to achieve the environmental objectives of the European Union's (EU) strategies towards reducing carbon emissions and energy dependency on fossil fuels. When tackling retrofitting projects, the issue of scale becomes essential as sometimes this can determine the sustainability of the project. Therefore, a comprehensive approach is essential to ensure effective decision-making. A platform has been designed within the EU funded OptEEmAL project to support stakeholders in this process, providing functionalities that can automatically model and evaluate candidate retrofitting alternatives considering their priorities, targets and boundary conditions. A core element of this platform is the evaluation framework deployed which implements a multi-criteria decision-making approach to transform the priorities of stakeholders into quantifiable weights used to compare the alternatives. As a result, more informed decisions can be made by the stakeholders through a comprehensive evaluation of the candidate retrofitting scenarios. This paper presents the approach followed to develop and integrate this evaluation framework within the platform as well as its validation in a controlled environment to ensure its effectiveness. [ABSTRACT FROM AUTHOR]
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- 2019
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13. Hypomagnesaemia of hereditary renal origin
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Rodriguez-Soriano, Juan, Vallo, Alfredo, and García-Fuentes, Miguel
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- 1987
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14. Five year trends on total and abdominal adiposity in Spanish adolescents
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Moreno, Luis A., Moliner-Urdiales, Diego, Ruiz, Jonatan R., Mesana Graffe, María Isabel, Vicente Rodríguez, Germán, Rodríguez, G., Fleta, Jesús, León Puy, Juan Francisco, García Fuentes, Miguel, Castillo, Manuel J., González Gross, M., and Marcos, A.
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Secular trends ,Adiposidad ,Tendencias seculares ,Adolescencia ,Abdominal fat ,nutritional and metabolic diseases ,Body fat percentage ,Porcentaje de grasa corporal ,Grasa abdominal ,Adiposity ,Adolescence - Abstract
8 páginas, 2 figuras, 2 tablas, Objective: To assess five years trends in total and abdominal fat in Spanish adolescents. Design: Two cross-sectional studies: adolescents from the city of Zaragoza (Spain) assessed during 2001-2002 and 2006-2007. Subjects: 399 adolescents in 2001-02 and 392 adolescents in 2006-07. Main outcome measurements: Socio-economic status was assessed using the education level of both parents. A complete anthropometric assessment was performed in both surveys using the same methodology: weight, height, skinfold thickness (biceps, triceps, subscapular, suprailiac, thigh and calf) and circumferences (waist and hip). The body mass index (BMI) and the sum of 6 skinfold thicknesses were calculated. Body fat percentage (BF%) was also calculated by the formulas described by Slaughter et al. Results: After adjusting for age and pubertal status, only females showed a significantly decrease in weight, BMI and waist circumference, and a significant increase in the sum of 6 skinfolds (all P < 0.05 and Cohen’s d ≥ 0.25) in 2006-2007, when compared to values obtained in 2001-2002. Males did not show any significant change between the two surveys. Concerning centile values, a slight general reduction was observed in weight, BMI and waist circumference for both males and females. On the contrary, the sum of 6 skinfolds and the BF% were higher in 2006-2007 than in 2001-2002. Conclusion: According to these results, there might be a levelling-off in the trends of BMI, BF% and waist circumference in male adolescents from Zaragoza. In females, despite a trend towards higher body fat mass, there was a trend towards lower BMI and waist circumference values., Spanish Ministry of Health, FIS (00/0015) and grants from Panrico S.A., Madaus S.A. and Procter & Gamble S.A. The HELENA Study was carried out with financial support of the European Community Sixth RTD Framework Programme (Contract FOOD-CT-2005-007034). This study was also supported by the Spanish Ministry of Education (EX-2007-1124, EX-2008-0641, DEP2007- 29933-E, AP2006-02464). LAM, MIM, GVR, GR, JF, and MGF were also supported by a grant from the Spanish Ministry of Health: Maternal, Child Health and Development Network (number RD08/0072).
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- 2012
15. Individual and Combined Effects of ApoE and MTHFR 677C/T Polymorphisms on Cognitive Performance in Spanish Adolescents: The AVENA Study RID C-7661-2009
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Ruiz, Jonatan R., Castillo, Ruth, Labayen, Idoia, Moreno López, Luis A., García Fuentes, Miguel, González Lamuno, Domingo, Álvarez Granda, Jesús L., Lucía Mulas, Alejandro, Ortega, Francisco B., and Avena Study Group
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Cognición ,Psicología del adolescente - Abstract
Objective To examine the individual and combined associations of ApoE and MTHFR 677C/T polymorphisms with cognitive performance in adolescents. Study design The study comprised 412 Spanish adolescents (13 to 18.5 years of age). Cognitive performance (verbal, numeric and reasoning abilities, and an overall score) was measured by the Spanish-version of the SRA-Test of Educational-Ability. Results We observed no differences in the cognitive performance study variables in adolescents carrying or not carrying the ApoE epsilon 4 variant. Adolescents without the MTHFR 677TT genotype had significantly better cognitive performance than their TT peers. The analysis of the combined effect of these polymorphisms revealed that those individuals carrying both the ApoE epsilon 4 variant and the MTHFR 677TT genotype had significantly worse cognitive performance than their peers with other genotype combinations. These findings were independent of sex, age pubertal status, socioeconomic status, physical activity, and skipping breakfast. Conclusions The results of the present study suggest that the ApoE epsilon 4 alone is not associated with cognitive performance in adolescents. Individuals with the MTHFR 677TT genotype had slightly impaired cognitive performance, whereas we observed a combined effect of both the ApoE epsilon 4 variant and the MTHFR 677TT genotype on cognitive performance. More research is needed in larger population samples to corroborate our findings. (J Pediatr 2010;156:978-84). 4.042 JCR (2010) Q1, 3/109 Pediatrics UEM
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- 2010
16. Breast-feeding and risk of hospitalization for all causes and fever of unknown origin.
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Pardo-Crespo, Rosa, Pérez-Iglesias, Rocio, Llorca, Javier, Álvarez-Granda, Lino, García-Fuentes, Miguel, Martínez-González, Miguel Ángel, and Delgado-Rodríguez, Miguel
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BREASTFEEDING ,INFANT nutrition ,RESPIRATORY infections in children ,GASTROINTESTINAL diseases ,PEDIATRICS ,HOSPITAL care - Abstract
Background: Breast-feeding has shown to give a reduction in the risk of hospitalization due to respiratory tract infections and gastrointestinal conditions during the first two years of life. The association of breast-feeding with all admission causes and with fever of unknown origin (FUO) was analysed. Methods: A case-reference study in Cantabria (northern Spain) was carried out. Cases (n=336) were hospitalized children aged less than 24 months at University of Cantabria Hospital; the reference was a 1:1 matched (by time from delivery to admission) sample of children from mothers delivering at the same hospital. Information on breast-feeding, socio-economic variables and employment were obtained. Odds ratios (ORs), their 95% confidence intervals (CIs), and mean length of breast-feeding were estimated after adjusment for confounding variables. Result: In the reference population, shorter duration of breast-feeding was associated with smoking, lower educational level, and less privileged social strata. The frequency of breast-feeding was higher in the reference than in the cases, 82.3% vs 75.6% (p=0.023). Significant negative trends were noted in univariate analyses between the length of breast-feeding and both all admission causes and FU0, although the statistical significance was lost after adjusting for confounding variables (educational level, social class, smoking, and use of incubator after delivery). The adjusted mean length of breast-feeding was shorter in hospitalized children ≤ 6 months old for both all admission causes (40.6 ± 5.4 vs 99.5 ± 5.4, p<0.001) and FUO (40.8 ± 12.4 vs 91.7 ±12.4, p=0.006). Conclusion: Breast-feeding time is shorter in hospitalized children for both all admission causes and FU0. [ABSTRACT FROM AUTHOR]
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- 2004
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17. To Examine Appropriate Deep-retrofit Practice using Simulation Results in an EU-funded Urban Regeneration Project.
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Cui, Jia Michelle, Ianakiev, Anton, and García-Fuentes, Miguel Á.
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This paper is based on a recently completed feasibility research – report of the Passivhaus standard retrofitting innovation activities – for the EU Horizon 2020 project REMOURBAN (REgeneration MOdel for accelerating the smart URBAN transformation). REMOURBAN is a major Future Cities demonstrator project supported by an investment of EU Lighthouse project scheme [1] . A block of terraced houses, which is one of the eight archetypes to be retrofitted at Nottingham demo site, will be cost-effectively retrofitted to a high energy-efficiency standard. Both static and dynamic simulation results play important roles in identifying appropriate retrofit standards and practice to achieve expected energy savings for such a major investment project. This paper aims to explore the building simulation effect on predicting the improvement potential in terms of energy savings under various refurbishment scenarios in the early project stage. The current feasibility study ushers the next project phases of implementation and real-time field monitoring, when detailed simulations are also expected to play important roles. [ABSTRACT FROM AUTHOR]
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- 2016
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18. Interplay Between Weight Loss and Gut Microbiota Composition in Overweight Adolescents.
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Santacruz, Arlette, Marcos, Ascensión, Wärnberg, Julia, Martí, Amelia, Martin-Matillas, Miguel, Campoy, Cristina, Moreno, Luis A., Veiga, Oscar, Redondo-Figuero, Carlos, Garagorri, Jesús M., Azcona, Cristina, Delgado, Manuel, García-Fuentes, Miguel, Collado, Maria C., and Sanz, Yolanda
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WEIGHT loss ,OVERWEIGHT persons ,OBESITY ,BODY weight ,NUTRITION disorders - Abstract
The aim of this study was to determine the influence of an obesity treatment program on the gut microbiota and body weight of overweight adolescents. Thirty-six adolescents (13–15 years), classified as overweight according to the International Obesity Task Force BMI criteria, were submitted to a calorie-restricted diet (10–40%) and increased physical activity (15–23 kcal/kg body weight/week) program over 10 weeks. Gut bacterial groups were analyzed by quantitative real-time PCR before and after the intervention. A group of subjects (n = 23) experienced >4.0 kg weight loss and showed significant BMI (P = 0.030) and BMI z-score (P = 0.035) reductions after the intervention, while the other group (n = 13) showed <2.0 kg weight loss. No significant differences in dietary intake were found between both groups. In the whole adolescent population, the intervention led to increased Bacteroides fragilis group (P = 0.001) and Lactobacillus group (P = 0.030) counts, and to decreased Clostridium coccoides group (P = 0.028), Bifidobacterium longum (P = 0.031), and Bifidobacterium adolescentis (P = 0.044) counts. In the high weight–loss group, B. fragilis group and Lactobacillus group counts also increased (P = 0.001 and P = 0.007, respectively), whereas C. coccoides group and B. longum counts decreased (P = 0.001 and P = 0.044, respectively) after the intervention. Total bacteria, B. fragilis group and Clostridium leptum group, and Bifidobacterium catenulatum group counts were significantly higher (P < 0.001–0.036) while levels of C. coccoides group, Lactobacillus group, Bifidobacterium, Bifidobacterium breve, and Bifidobacterium bifidum were significantly lower (P < 0.001–0.008) in the high weight–loss group than in the low weight–loss group before and after the intervention. These findings indicate that calorie restriction and physical activity have an impact on gut microbiota composition related to body weight loss, which also seem to be influenced by the individual's microbiota. [ABSTRACT FROM AUTHOR]
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- 2009
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19. Truncal and Abdominal Fat as Determinants of High Triglycerides and Low HDL-cholesterol in Adolescents.
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Tresaco, Beatriz, Moreno, Luis A., Ruiz, Jonatan R., Ortega, Francisco B., Bueno, Gloria, González-Gross, Marcela, Wärnberg, Julia, Gutiérrez, Angel, García-Fuentes, Miguel, Marcos, Ascensión, Castillo, Manuel J., and Bueno, Manuel
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FAT ,ADIPOSE tissues ,TRIGLYCERIDES ,HIGH density lipoproteins ,CHOLESTEROL ,LOW-cholesterol diet - Abstract
We examined whether abdominal and truncal adiposity, assessed with simple anthropometric indices, determines serum triglycerides and high-density lipoprotein (HDL)–cholesterol levels independently of total adiposity amount in adolescents. A total of 547 Spanish adolescents (284 males and 263 females) aged 13–18.5 years were included in this study. Measures of truncal adiposity included subscapular to triceps ratio, and trunk-to-total skinfolds ratio (TTS%). Waist circumference was used as a surrogate of abdominal adiposity, and BMI was used as a measure of total adiposity. The results of the regression models indicated that levels of triglycerides were positively associated with waist circumference and TTS% after controlling for age and Tanner stage in both sexes. Once BMI was entered in the model, these associations remained significant for waist circumference in females. HDL-cholesterol levels were negatively associated with waist circumference in both sexes, and with subscapular to triceps ratio and TTS% in males, after controlling for age and Tanner stage. Once BMI was entered in the model, these associations remained significant for subscapular to triceps ratio and for TTS% in males. The results of this study suggest that in male adolescents, truncal adiposity is negatively associated with levels of HDL-cholesterol, whereas in females, abdominal adiposity is positively associated with levels of triglycerides independently of total adiposity. These findings highlight the deleterious effect of both truncal and abdominal fat depots on the lipid profile already from the first decades of life.Obesity (2009) 17 5, 1086–1091. doi:10.1038/oby.2008.626 [ABSTRACT FROM AUTHOR]
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- 2009
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20. EXPRESSION AND REGULATION OF THE TRANSCRIPTIONAL REPRESSOR ZNF43 IN EWING SARCOMA CELLS.
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González-Lamuño, Domingo, Loukili, Noureddine, García-Fuentes, Miguel, and Thomson, Timothy M.
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GENETIC repressors ,GENETIC transcription ,CANCER cells ,SARCOMA - Abstract
In vitro, cells derived from Ewing sarcoma (ES) with the characteristic somatic rearrangement between the genes EWS and FLI1 can be induced to differentiate toward a neuronal phenotype by exposure to agents such as dibutyryl cyclic AMP (db cAMP) or retinoic acid. Therefore, expression of the chimeric Ews-Fli1 protein does not irreversibly block the capacity of Ewing cells to engage in the neuronal differentiation program initiated by these agents. To identify genes that might be involved in the maintenance of Ewing cells in their undifferentiated state, a PCR-based differential display method was used to compare gene expression patterns in Ewing cell lines with those induced to differentiate toward a neuronal phenotype. A cDNA was expressed at high levels in proliferating Ewing-derived EW-1 cells and downregulated in EW-1 cells induced to differentiate, which corresponds to ZNF43, a multi-zinc finger protein containing the Krüppel-associated box (KRAB) transcriptional repression domain. Treatment of EW-1 cells with antisense oligonucleotides complementary to ZNF43 mRNA induces morphological differentiation and growth arrest. These findings suggest a role for ZNF43 in the maintenance of ES cells in an undifferentiated state, and that ZNF43 could be a primary target for differentiation stimuli in Ewing cells. [ABSTRACT FROM AUTHOR]
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- 2002
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21. Long-Chain Polyunsaturated Fatty Acids in Rat Maternal Milk, Offspring Brain and Peripheral Tissues in Essential Fatty Acid Deficiency.
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García-Calatayud, Salvador, Ignacio Ruiz, José, García-Fuentes, Miguel, Dierssen, Mara, Flórez, Jesús, and Sanjurjo Crespo, Pablo
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- 2002
22. Evaluation of Results of City Sustainable Transformation Projects in the Fields of Mobility and Energy Efficiency with Real Application in a District in Valladolid (Spain).
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García-Fuentes, Miguel Á., Antolín, Javier, de Torre, Cristina, Pérez, Ana, Tomé, Isabel, Mirantes, María L., López, Fátima, Martín, Javier, and Gómez, Jaime
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This paper presents a novel evaluation framework to assess the effectiveness of city transformation projects related to energy efficiency and sustainable mobility actions. The evaluation framework is part of an Urban Regeneration Model designed to accelerate the urban transformation toward the smart city concept, taking into account all aspects of sustainability. This model has been developed and validated in the three EU cities (Valladolid, Spain; Nottingham, United Kingdom; and Tepebaşı, Turkey) where interventions in the energy, mobility, and ICT fields have been deployed. This model relies on an Evaluation Framework to support its main phases considering two levels of evaluation: city level, to assess globally the smartness and sustainability of the city, and project level, to support the decision-making and assess the impacts of specific implementations. This paper is focused on the second level and its application through the evaluation-supporting tool STILE in the assessment of the energy efficiency and sustainable urban mobility actions implemented in the city of Valladolid. The assessment analysis has allowed assessing how the energy efficiency interventions carried out in the Valladolid district have reduced the energy consumption, increased the use of renewable energies, and reduced the CO
2 emissions. In addition, it has allowed evaluating other aspects such as the air quality, thermal comfort, and energy bill, which have been also improved for the residents. Considering the analysis of the sustainable mobility interventions, the evaluation framework supports the assessment of the reduction of emissions and air pollutants and how the actions have converted electro-mobility into a real option for citizens. The evaluation of results after the implementation of this kind of actions is key to ensuring that successful actions can be replicated in other places achieving smarter and more sustainable cities. [ABSTRACT FROM AUTHOR]- Published
- 2021
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23. Henoch-Schönlein purpura in adulthood and childhood. Two different expressions of the same syndrome.
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Blanco, Ricardo, Martínez-Taboada, Víctor M., Rodríguez-Valverde, Vicente, García-Fuentes, Miguel, and Gonzalez-Gay, Miguel A.
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- 1997
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24. Development of an Evaluation Framework for Smartness and Sustainability in Cities.
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Antolín, Javier, de Torre, Cristina, García-Fuentes, Miguel Á., Pérez, Ana, Tomé, Isabel, Mirantes, María L., and Hoyos, Elena
- Abstract
The transformation of cities into smarter and more sustainable environments is essential towards achieving the objectives of the decarbonization of the economy. In this sense, holistic strategies are required to design and implement urban regeneration strategies. The EU-funded REMOURBAN project has developed an Urban Regeneration Model which provides the mechanisms to implement more efficiently these processes, integrating technologies, business models, management procedures and evaluation mechanisms, where the evaluation is sought as the main supporting mechanism throughout the various phases of the city transformation process. The framework developed considers two levels of evaluation: city level, to assess both sustainability and smartness of the city as a whole from a comprehensive and integrated perspective, and project level, to provide a clear identification of the impact of implementation of technologies and solutions on three key priority areas (sustainable districts and built environment, sustainable urban mobility and integrated infrastructures and processes) aimed at achieving the city high-level goals. This paper introduces the Urban Regeneration Model and describes the evaluation framework and its implementation in the city of Valladolid (Spain). [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
25. Integration of Prioritisation Criteria in the Design of Energy Efficient Retrofitting Projects at District Scale: A Case Study.
- Author
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García-Fuentes, Miguel Á., Álvarez, Sonia, Serna, Víctor, Pousse, Maxime, and Meiss, Alberto
- Abstract
The evident need for improving the existing building stock still suffers from important barriers, such as the fragmentation of the value chain, the lack of information regarding some solutions, and the lack of confidence with respect to energy savings, which prevent unlocking investments, and the difficult communication among stakeholders. Therefore, new processes based on exploiting the potential of existing and new tools are required. In this framework, the OptEEmAL project has developed a tool that integrates stakeholders, data and tools in order to ease the process of designing energy efficient retrofitting projects at building and district scale. This tool works around an optimisation framework in order to evaluate, compare and optimise candidate retrofitting scenarios against a set of indicators showing the performance of the district. This evaluation and optimisation method is based on aggregating indicators through transforming the priorities of stakeholders into a mathematical weighting scheme, which makes it possible to provide scenarios within their expectations. Therefore, the generation of these scenarios is driven by their design parameters, being thus flexible and adapted to their needs. This paper shows the implementation of this tool and specifically 3 different prioritisation schemes, analysing how they impact into the decision making process and selection of the retrofitting strategy. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
26. Simulation model generation combining IFC and CityGML data
- Author
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Lilis Georgios-Nektarios, Giannakis Georgios, Katsigarakis Kyriakos, Goncal Costa, Álvaro Sicilia, García Fuentes, Miguel, and Rovas Dimitrios
- Subjects
Energy efficiency - Abstract
Summarization: The energy efficiency requirements at district scale revealed the need for detailed building energy simulations, with which the overall district energy demand can be estimated with an acceptable degree of accuracy. In order to meet this need, an automated simulation model generation process is introduced at the context of the European project OptEEmAL, which includes: a query stage where data are gathered from IFC, CityGML files, and a transformation stage where a single IDF file is generated for a building in a district environment, suitable for EnergyPlus simulations. The queried data are assumed to conform to certain correctness, completeness and consistency conditions across district and building scales. As a demonstration example, a simulation model is generated for a specific building. Future improvements of this work are discussed related to the integration of all the data requirements of the proposed process, in a District Data Model under an ontological framework. Παρουσιάστηκε στο: 11th European Conference on Product and Process Modelling
27. Novel Design Support Methodology Based on a Multi-Criteria Decision Analysis Approach for Energy Efficient District Retrofitting Projects.
- Author
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García-Fuentes, Miguel Á., García-Pajares, Rubén, Sanz, Cecilia, and Meiss, Alberto
- Subjects
- *
METHODOLOGY , *MULTIPLE criteria decision making , *RETROFITTING , *MAINTENANCE , *FACILITY management - Abstract
Districts can be considered as a system of complex interconnections, interactions, relationships and flows. Therefore, a comprehensive approach is essential for effective decision-making with regards to energy efficiency improvement. When addressing interventions with a wider scale, the range of possible interventions is greater, as well as the possibilities of new business models to make bankable the interventions. However certain barriers can appear linked to the interactions among stakeholders, which are usually more complex than when tackling individual actuations. To overcome these barriers it is necessary to establish integrated and systemic methodologies able to support stakeholders to implement better collaboration approaches and carry out more informed decisions. These decisions should be based on a set of relevant indicators, calculated at district level, capturing the different stages that form the retrofitting process (from the diagnosis to the final assessment). This paper presents a holistic design methodology based on the application of a Multi-Criteria Decision Making approach that allows designing optimised solutions. This methodology is based on the evaluation of a set of District Sustainability Indicators while proposing an Integrated Project Delivery method improving the communications among stakeholders and, therefore, the decision-making process. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
28. Dancing Queer Tango: An Experience of Queer Pedagogy in PESTE.
- Author
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Pereira-García, Sofía, López-Cañada, Elena, and Elling-Machartzki, Agnes
- Subjects
TANGO (Dance) ,POSTSECONDARY education ,PHYSICAL education ,VIDEO recording ,HETERONORMATIVITY ,PHYSICAL mobility - Abstract
Purpose: The lesbian, gay, bisexual, transgender/transsexual, and queer/questioning students normally occupy a marginalized and at-risk position in classes and especially in physical education. In this paper, the authors explore the ways in which queer tango can contribute to counteracting heteronormativity and opening up students to new interactions and identifications through the performance of different gender performances in Physical Education and Sport Tertiary Education. Method: A queer tango session was carried out with 111 university students (91 men and 19 women aged 19–22 years). Data were obtained from interviews, video records, and open questionnaires about the practice. Results: The findings reveal that the performance of dance roles that are contrary to the heteronormative order reinforced both heteronormativity and queer embodiments in Physical Education and Sport Tertiary Education. Conclusion: An isolated activity is not enough, and more queer pedagogical practices should be introduced in order to make meaningful changes to mainstream students' ideology and behaviors. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
29. Age-of-the-air in rooms according to the environmental condition of temperature: A case study.
- Author
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Meiss, Alberto, Feijó-Muñoz, Jesús, and García-Fuentes, Miguel A.
- Subjects
- *
INDOOR air quality , *COMPUTATIONAL fluid dynamics , *AIR flow , *ATMOSPHERIC temperature , *BUILDINGS & the environment - Abstract
Highlights: [•] Convective strengths prevail with respect to the direction imposed on the air inlet. [•] Changes in age of the air depend on the flow pattern established by the temperatures. [•] The interchange of the energy causes the room average age not to change significantly. [•] CFD tools are very useful for the study of the airflows in rooms. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
30. Experiences of LGBTQ+ individuals in sports in Germany.
- Author
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Hartmann-Tews, Ilse, Menzel, Tobias, and Braumüller, Birgit
- Abstract
There is growing international evidence that lesbian, gay, bisexual, transgender, queer, and sexually/gender diverse (LGBTQ+) people regularly experience discrimination in sports. However, there is a lack of empirical research with regard to the sports situation in Germany. Based on a quantitative survey of 858 self-identifying LGBTQ+ individuals, the present research is the first to provide a comprehensive picture of the experiences of LGBTQ+ people in sports in Germany. To add distinctive knowledge to the international research, this analysis considers differences within the group of LGBTQ+ people and between various sports settings (i.e., organizational framework, team vs individual sports, and performance level. Two research questions are addressed: (1) What micro- and meso-level factors affect the witnessing of homo-/transnegative language and the prevalence of homo-/transnegative incidents in respondents' sports activities? (2) What micro- and meso-level factors affect respondents' feelings of being offended by homo-/transnegative language and what behavioral consequences (i.e., refraining from specific sports and reactions to homo-/transnegative episodes) can be observed among different LGBTQ+ subgroups? The data reveal the impact of the sports context on the perception of homo-/transnegative language but not on negative experiences. Moreover, there is a higher prevalence of gay compared to lesbian athletes with regard to the perception of homo-/transnegative language in their sports and a higher prevalence of gay athletes and non-cisgender (transgender) athletes with regard to homo-/transnegative experiences in sport compared to lesbian and cisgender athletes. The empirical evidence confirms and deepens international findings. Moreover, the data assist the Sport Ministers Conference's goal of increasing initiatives to tackle the exclusion and discrimination faced by LGBTQ+ people in sports. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
31. The A–Z of Social Justice Physical Education: Part 2.
- Author
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Landi, Dillon, Lynch, Shrehan, and Walton-Fisette, Jennifer
- Subjects
OBESITY ,PHYSICAL education ,POPULATION geography ,PREJUDICES ,REFLECTION (Philosophy) ,SCHOOL administration ,SELF-efficacy ,SOCIAL justice ,PROFESSIONAL practice ,LGBTQ+ people - Abstract
Education has the ability to both reproduce and transform broader social structures. Yet, teachers' responsibilities are constantly increasing whilst budgets, resources, and staffing are depleted. We argue that we are living in a time of great uncertainty and precarity. As physical educators, we should make attempts to be socially conscious of this precarity and provide equitable environments for all students. This article (the second installment of a two-part series) is an attempt to make an important step in enacting a socially just and informed physical education program. In so doing, we highlight specific ways that teachers and teacher educators can prepare for and teach about precarity in physical education. By providing resources, readings, and examples from practice, we provide a framework that promotes ethics of value, care, and zeal for others. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
32. Acknowledgment to Reviewers of Smart Cities in 2021.
- Published
- 2022
- Full Text
- View/download PDF
33. Acknowledgment to Reviewers of Sensors in 2020.
- Subjects
DETECTORS - Published
- 2021
- Full Text
- View/download PDF
34. Acknowledgment to Reviewers of Energies in 2020.
- Subjects
RESEARCH institutes ,GOVERNMENT laboratories - Published
- 2021
- Full Text
- View/download PDF
35. Acknowledgment to Reviewers of Sustainability in 2020.
- Abstract
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that I Sustainability i maintains its standards for the high quality of its published papers. Thanks to the cooperation of our reviewers, in 2020, the median time to first decision was 15 days and the median time to publicaPawlewicztion was 38 days. The editors would like to express their sincere gratitude to the following reviewers for their precious time and dedication, regardless of whether the papers were finally published:MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. [Extracted from the article]
- Published
- 2021
- Full Text
- View/download PDF
36. Acknowledgement to Reviewers of Future Internet in 2019.
- Subjects
INTERNET - Abstract
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal's rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not. The editors would like to express their sincere gratitude to the following reviewers for their generous contribution in 2019:. [Extracted from the article]
- Published
- 2020
- Full Text
- View/download PDF
37. Acknowledgement to Reviewers of Electronics in 2019.
- Subjects
ELECTRONICS ,AMARANTHUS palmeri - Published
- 2020
- Full Text
- View/download PDF
38. Equity, Diversity and Inclusion in Sport Organizations
- Author
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Amélie Keyser-Verreault, Sophie Brière, Marilou St-Pierre, Guylaine Demers, Diane Culver, Amélie Keyser-Verreault, Sophie Brière, Marilou St-Pierre, Guylaine Demers, and Diane Culver
- Subjects
- Athletic clubs--Management, Minorities in sports, Minorities in sports--Que´bec (Province), Sexual minorities and sports
- Abstract
Women, people with disabilities and LGBTQ2+ people are more present on the sports scene, but important transformations are still needed in organizations so that these people are better represented and included in all sports disciplines. This book, which is the result of a research project conducted with sports organization managers, coaches, athletes, experts and other stakeholders in the field, proposes concrete solutions for sport organizations. Throughout the book we propose and explain good practices in the area of equity, diversity and inclusion (EDI). Together with numerous testimonials and examples from the field, these practices adapted to the sport environment make it possible to overcome the barriers that prevent women and people from historically marginalized groups from participating in sport and from reaching leadership positions within these organizations. The practices presented in this book are based on an analytical framework for inclusion in organizations that can be applied beyond the Quebec and Canadian context.
- Published
- 2024
39. Sport, Identity and Inclusion in Europe : The Experiences of LGBTQ People in Sport
- Author
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Ilse Hartmann-Tews and Ilse Hartmann-Tews
- Subjects
- Sports--Europe--Sociological aspects, Sexual minorities--Europe--Identity
- Abstract
This book explores and critically assesses the challenges and experiences of LGBTQ people within sport in Europe. It presents cutting-edge research data and insights from across the continent, with a focus on sport policy, sport systems, and issues around anti-discrimination and inclusion.The book introduces the theoretical and methodological foundations of research into LGBTQ people in sport and then presents in-depth comparative surveys of systems and experiences in Austria, Belgium, France, Germany, Hungary, Italy, the UK, and Spain. A final section considers the effectiveness of policy in this area and motives for participation, and looks ahead at future directions in research, policy, and practice.Tracing the frontiers of our understanding of the experiences of LGBTQ people in contemporary Europe, this is fascinating reading for anybody with an interest in the sociology of sport, sport policy, LGBTQI studies, gender and sexuality studies, or cultural studies.The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
- Published
- 2022
40. Smart Cities : Third Ibero-American Congress, ICSC-Cities 2020, San José, Costa Rica, November 9-11, 2020, Revised Selected Papers
- Author
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Sergio Nesmachnow, Luis Hernández Callejo, Sergio Nesmachnow, and Luis Hernández Callejo
- Subjects
- Smart cities--Congresses
- Abstract
This book constitutes the thoroughly refereed proceedings of the Third Ibero-American Congress, ICSC-CITIES 2020, held in Costa Rica, in November 2020. Due to the COVID-19 pandemic the conference was held online. The 21 full papers presented were carefully reviewed and selected from 99 submissions. The papers are organized on topical sections on Energy Efficiency and Sustainability; Mobility and IoT; Infrastructure, Environment, Governance.
- Published
- 2021
41. Polo in Argentina : A History
- Author
-
Horace A. Laffaye and Horace A. Laffaye
- Subjects
- Polo--Argentina--History
- Abstract
This work--the first of its kind in more than sixty years--covers polo in Argentina, from its beginnings in the 1870s to the summer of 2013. The history of the early pioneers is constructed with data not previously published, gathered from contemporary sources. International competitions are covered and include the Olympic Games, the Cup of the Americas and the World Championships. Particular attention is given to the major clubs, the Argentine and Hurlingham Open Championships, and the National Handicap Tournament. Several of the elite players merit individual or family mini-biographies. Myths in Argentine polo are also debunked, based upon careful analysis of contemporary sources. Travels abroad by Argentine teams are fully described as are the foreign teams that competed in Argentina. The work is enhanced by the author's personal observation of significant events and friendship with many of the participants.
- Published
- 2014
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