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Direct analysis in real-time mass spectrometry (DART-MS) is an emerging in-situ ionization mass spectrometry analysis technology in recent years. DART is a non-contact surface desorption ionization technique, which is based on the principle of using helium or nitrogen as the working gas and generating excited high-energy particles by electric discharge. The excited state particles are accelerated by rapid heating and electric force, which instantly ionize the volatile compounds on the surface of the sample to be measured under atmospheric pressure, and then detected by mass spectrometry, thus achieving real-time direct analysis of the sample. DART-MS has the characteristics of simple sample preparation, quick and in-situ analysis. Since DART-MS was reported in 2005, it has become one of the most broadly used direct analysis methods and is extensively applied for the direct analysis of the quality, safety, origin and characteristics of food samples. Besides, it has been widely used in biomedicine, environmental monitoring, public safety, and drug analysis as well. Traditional Chinese medicines (TCMs) have been used for thousands of years in China, which gradually move towards to the world arena. The composition of TCM is very complicated, often containing many different chemical components of different types and properties, such as flavonoids, alkaloids, terpenoids, etc. Therefore, the analysis of the chemical basis of the efficacy and quality evaluation of TCMs are very crucial. In recent years, the development of DART-MS technology has provided many new opportunities for direct and rapid analysis of active ingredients in TCMs. The review was focused on the applications of DART-MS in TCMs, which covered the principle, characteristics, influencing factors and technological progress of DART-MS technology, and systematically summarized the research and application of this technology in TCMs, including qualitative and quantitative analysis. In addition, this review briefly introduced the progress of the application of DART-MS in combination with other techniques, such as thin-layer chromatography, imaging mass spectrometry and solid-phase microextraction in the profiling of TCMs, and provided further perspectives on its application development.

Objective: In this study, the finite element simulation was integrated into random vibration experiment to provide a new way of thinking about transportation packaging. Methods: The red wine inner packaging spacer, made of three different cushioning materials, was used as the research object, and the vibration response was studied through random vibration experiment. Then the finite element simulation was used to analyze the correlation between the experiment and the simulation results. Results: The results of random vibration test were highly consistent with the results of finite element simulation, and the finite element simulation was less material-and time-consuming, compared with the random test. Conclusion: The combination of random experiment and finite element method can improve the efficiency of the experiment. The finite element simulation method can provide effective guidance for the analysis and design of product inner packaging under the vibration environment of transportation.

'Mung Bean Rock' or 'Green Bean Rock' is a type of clay-like rock formed by Paleomatization and diagenesis. These rocks are distributed mainly between early and middle Triassic strata in Southwestern China and are good regionally isochronal mark beds. Studying the diagenetic age of 'Mung Bean Rock' is of great significance for further understanding of its diagenetic mechanism and age background. The debris zircon of 'Mung Bean Rock' in Chongqing Tongliang was used for U-Pb dating by LA-ICP-MS in this study. The zircon crystals have almost complete shape and zoning textures with high U and Th content, typical of magma zircon. Weighted average ages of the zircon 206Pb/238U peak at 245.86±0.98 Ma and 277.6±3.8 Ma. 'Mung Bean Rock' is located in the base of the Leikoupo Formation, the age of 245.86 Ma represents the timing of the zircons entering the sedimentary basin with volcanic ash at the base of the Leikoupo Formation in Tongliang, Chongqing. The age is similar to that of the tuff in Guizhou and Guangxi, indicating that regional volcanic eruption occurred at around 246 Ma. The older zircon was brought into the sedimentary basin during weathering of early igneous rocks and deposited with 'Mung Bean Rock'. A peak age at 277 Ma may imply that there was magmatic activity in the middle Permian period.

The Dazhuyuan bauxite deposit is one of the most important deposits discovered during recent decades, and the Wuchuan-Zheng'an-Daozhen bauxite area (simplified as Wuzhengdao area) has also been listed as one the first uncompartmentalized prospecting areas on the national level. In order to promote prospecting, it is urgent to summarize the characteristics of the Dazhuyuan typical deposit and the regional ore-forming condition and outline the metallogenic regularity for the Wuzhengdao bauxite area. Based on the analysis of ore-bearing strata, structure, paleoclimatology, palaeogeomorphology and palaeogeography, the distribution of ore-bearing strata (the Dazhuyuan Formation, C2d), the existence of ore-source strata (Hanjiadian Formation, S1hj), the dissolution of limestone from the basement (the Huanglong Formation, C2h), and the stable stretching of syncline are identified as the most four most important key-points for the further prospecting of bauxite deposits in this area. The Liyuan-Luchi syncline, the Zhangjiayuan syncline, the Datang syncline, the Xinmo syncline, the Daozhen syncline, the Taoyuan syncline, the Anchang syncline and the Huanxi syncline have also been chosen as the main targets for uncompartmentalized prospecting and ore-genetic models for different kinds of bauxite deposits have been built, clearing the key exploration prospecting direction. Since 2012, three superlarge-scale, four large-scale and three middle-scale bauxite deposits have been discovered and about 470 million ton of bauxite have been confirmed, which show a remarkable result of uncompartmentalized prospecting in the Wuzhengdao area, North Guizhou. The regularity and ore-genetic model for bauxite deposits, based on practice, can provide scientific evidence for uncompartmentalized prospecting and further exploration in the Wuzhengdao area.

Equipment for breaking and blasting large barriers (EBBLB) is new break-blast equipment, which inevitably induces ground vibration and may cause substantial damage to rock mass and nearby structures as well as human beings. The ground vibration induced by break-blast is one of the inevitable outcomes. By monitoring vibration at measuring points at different distances from blasting center, time history curve of vibrating velocity can be obtained; it can be drawn that blasting seismic waves are generated mainly from the explosion of the precharge. Furthermore, different approaches have been adopted to fit relationship between particle peak velocity (PPV) and distance from blasting center, comparative analysis of which provides the most appropriate relation expression to predict attenuation of PPV of vibration with distance from blasting center. The relation between vibration frequency and distance from blasting center is obtained by Fourier transform. And the research decomposes vibrating signals in vertical direction of different distances from blasting center with Hilbert-Huang Transform (HHT), extracting information of empirical mode components of blasting vibration signals; thus vibrating signals are contracted by spectrum information and energy information, three-dimensional energy, and energy attenuation of vibration with different distances from blasting center. The study can predict ground vibration generated by EBBLB and assess its damaging effects of blasting vibration for security and protection.