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Natural hyperbolic materials can confine electromagnetic waves at the nanoscale. In this study, we propose a waveguide design that combines a high quality factor (FOM) with low loss, utilizing hexagonal boron nitride and graphene and gold substrate. The waveguide consists of a dielectric rib with a graphene layer sandwiched between two hBN ribs. Numerical simulations demonstrate the existence of two guided modes in the proposed waveguide within the second reststrahlen band (1360.0 cm−1

Objectives: To identify the dermatological system drugs that may be prescribed by Chinese dermatological nurses through expert consensus.

Radiation-related teeth damage is a common complication in nasopharyngeal carcinoma (NPC) patients undergoing radiotherapy (RT) that seriously affects their oral health-related quality of life (OHRQoL). However, few studies have focused on protecting teeth function. This study aimed to calculate dental dose limits based on OHRQoL. Analysis was performed on 96 NPC patients who received RT (all received routine pre-radiotherapy dental interventions in our department). Based on the General Oral Health Assessment Index (GOHAI), OHRQoL was assigned into poor (

C19H12ClF2N5O2, monoclinic, P21/n (no. 14), a = 14.405(9) Å, b = 7.579(5) Å, c = 17.610(9) Å, β = 95.856(13)°, V = 1913(2) Å3, Z = 4, Rgt(F) = 0.0464, wRref(F2) = 0.1134, T = 296 K.

There are no effective therapeutic options for locally advanced head and neck squamous cell carcinoma (HNSCC). Additionally, there is no standard therapy for patients subjected to multiple lines of treatment. Angiogenesis plays a key role in tumor growth and metastasis. Therefore, inhibition of tumor angiogenesis is an important strategy for tumor therapy. Apatinib is a novel tyrosine kinase inhibitor that inhibits angiogenesis by targeting vascular endothelial growth factor receptor-2 (VEGFR-2). The effect of apatinib on HNSCC has not been clearly established. In this study, we administered apatinib in combination with anti-epidermal growth factor receptor (EGFR) targeted and systemic chemotherapy for the treatment of oral cancer and to achieve better disease outcomes. To avoid fatal bleeding, after achieving good clinical outcomes, the follow-up treatment plan was adjusted. The efficacy of apatinib combined with anti-EGFR targeted and systemic chemotherapy for the treatment of oral cancer has not been previously reported. Our findings show the therapeutic potential of apatinib for advanced HNSCC patients with multiple lines of chemotherapy, especially for patients with large neck masses.

To evaluate the effects of calcium supplementation on bone mineral density in children.

A proton nuclear magnetic resonance (NMR)-based metabolomic study was used to characterize 2009, 2010, 2011, and 2012 vintages of Cabernet Sauvignon wines from Ningxia, which were vinified using the same fermentation technique. The pattern recognition methods of principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA), and orthogonal PLS-DA (OPLS-DA) clearly distinguished between the different vintages of wine driven by the following metabolites: valine, 2,3-butanediol, ethyl acetate, proline, succinic acid, lactic acid, acetic acid, glycerol, gallic acid, and choline. The PLS-DA loading plots also differentiated among the metabolites of different vintages. In the 2009 vintage wines, we found the highest levels of gallic acid, valine, proline, and 2,3-butanediol. The 2011 vintage wines contained the highest levels of lactic acid, and the highest levels of ethyl acetate, succinic acid, glycerol, and choline were observed in the 2012 vintage wines. We selected eight metabolites from the 1H NMR spectra that were quantified according to their peak areas, and the concentrations were in agreement with the results of PLS-DA and OPLS-DA analyses.

In coal-fired power plants, how to timely inventory coal storage, in order to optimize the coal stock, and improve coal blending operation, and then carry out economic dispatch scientifically and reasonably, has always been an important topic. The traditional way of artificial method has big error, high cost and serious waste of resources. Ultrasonic measurement technology is greatly affected by time difference and dust. Measurement technology based on computer vision requires interpolation to fit the correction model. The above methods all have large measurement errors and have been eliminated by the market. This paper mainly introduces coal measuring technologies based on laser and uav tilt photography which have been researched and applied more recently. Their respective installation methods, characteristics and applicable working occasions are analyzed. They have the common characteristic that the 3d coordinate point cloud data of coal yard surface needs to be solved before the 3d model of coal yard can be generated and the coal storage amount can be calculated. In the case that the 3d coordinate point cloud data of coal yard of power plant cannot be obtained directly, 3d reconstruction can be carried out by using 2d images of coal yard in coal report, or by using neural network model, and then the coal volume can be checked. This research idea is of great significance to realize effective and accurate supervision of coal storage in power plants..

In order to establish an accurate model of human knee joint, which lays a foundation for the follow-up finite element analysis of knee joint and biomechanics analysis, the paper based on the theory of biomechanics and MRI, with the help of professional modeling software, provides a 3D geometric model modeling and materialization processing method of knee joint, and established a total knee joint model including femur, tibia, fibular, meniscus, cartilage, ligament and other related structures.

In recent years, the wireless local networks are constructed rapidly and their coverage greatly increase. The passive radar imaging of moving targets using WiFi signals is studied in this paper, which may lead to wider applications of passive radars. Firstly, the ambiguity function of WiFi signals is analyzed. The results show that the WiFi signal has good range and velocity ambiguity and can be used as an illumination source. Then, distributed apertures are used to receive target echoes and the imaging is performed using a Generalized Likelihood Ratio Test (GLRT)-based approach. The positions and velocities of the moving targets can be reconstructed. The resolution of the imaging method is also analyzed. Simulation results demonstrate the performance of the presented passive radar imaging method of moving targets using WiFi signals.

Segmentation effect of super accumulation of heavy metals in plants which can reduce the concentration of metal ions in the cytoplasm of a cell is one of the important mechanisms of heavy metal detoxification. However, the compartmentalization effect from different tissues of a cell does not get a consistent conclusion. In order to evaluate whether intracellular compartmentalization could explain Cd detoxification mechanisms, the work described in this paper was designed to study the effect of exposure time and levels on Cd distribution of Indian mustard (Brassica juncea) at the cell and sub-cell level. Root and leaf samples were exposed to 0.5, 1.0, 2.0, 3.0 and 5.0 mg/L and harvested after 1, 5, 7, 10 and 14 days exposure. Cells were separated into three fractions: cytoderm, soluble fraction and organelle containing fraction using differential centrifugation technique, then Cr from all three fractions was determined by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Results showed that Cr in cytoderm, cytoplasm and organelles accounted for 50%-64%, 22%-38% and 7%-17% of total cadmium, respectively. It can be clearly indicated that the proportion of Cr in cytoderm is significantly higher than that in cytoplasm and organelles, indicating that compartmentalization of cytoderm plays a prominent role in Cd detoxification. As the exposure concentration and time increases, the content of Cd in cell fraction increases significantly especially after 7 days, which demonstrates that the effect of Cd on plant development is a slow process. Moreover, the excess of Cr stress concentration ( > 1.0 mg/L) would lead to deteriorative damage on plant cells, which was visually identified by TEM research, demonstrating different degrees of damages-plasmolysis, vacuolization and plasmalemma roughness, thus affecting the normal function of cells. These results suggest exposure time and levels are important parameters that must be taken into consideration in the study of the toxicity of heavy metals in plants.

【Abstract】Objective: To investigate the diagnos-tic and therapeutic effect of bronchofiberscopy in the manage-ment of severe thoracic trauma. Methods: A retrospective study was conducted on 207 consecutive patients with severe thoracic trauma enrolled in our hospital between January 2008 and June 2012. During the period, 488 bronchofiberscopies and lavages were done. The bronchofiberscope was inserted through tracheal inci-sion (282), nasal cavity (149) and oral cavity (57). Intensive SaO 2 monitoring as well as blood gas analysis were per-formed pre-, intra- and postoperatively. Simultaneously oxy-gen therapy or ventilatory support was given. Sputum cul-ture was done intraoperatively. Results: Diagnosis in 207 cases was confirmed by bronchofiberscopy. The result of sputum culture was posi-tive in 78 cases. Lavage was performed on 156 cases. SaO 2 significantly increased after bronchofiberscopies as well as lavages and PaO 2 obviously improved 2 h after surgery (both P

Animal husbandry is the main agricultural type over the Tibetan Plateau, above ground biomass (AGB) is very important to monitor the productivity for administration of grassland resources and grazing balance. The MODIS vegetation indices have been successfully used in numerous studies on grassland AGB estimation in the Tibetan Plateau area. However, there are considerable differences of AGB estimation models both in the form of the models and the accuracy of estimation. In this study, field measurements of AGB data at Sangke Town, Gansu Province, China in four years (2013-2016) and MODIS indices (NDVI and EVI) are combined to construct AGB estimation models of alpine meadow grassland. The field measured AGB are also used to evaluate feasibility of models developed for large scale in applying to small area. The results show that (1) the differences in biomass were relatively large among the 5 sample areas of alpine meadow grassland in the study area during 2013-2016, with the maximum and minimum biomass values of 3,963 kg DW/ha and 745.5 kg DW/ha, respectively, and mean value of 1,907.7 kg DW/ha; the mean of EVI value range (0.42-0.60) are slightly smaller than the NDVI’s (0.59-0.75); (2) the optimum estimation model of grassland AGB in the study area is the exponential model based on MODIS EVI, with root mean square error of 656.6 kg DW/ha and relative estimation errors (REE) of 36.3%; (3) the estimation errors of grassland AGB models previously constructed at different spatial scales (the Tibetan Plateau, the Gannan Prefecture, and Xiahe County) are higher than those directly constructed based on the small area of this study by 9.5%–31.7%, with the increase of the modeling study area scales, the REE increasing as well. This study presents an improved monitoring algorithm of alpine natural grassland AGB estimation and provides a clear direction for future improvement of the grassland AGB estimation and grassland productivity from remote sensing technology.