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Objective: Neurological complications are among the main causes of mortality and morbidity in antenatal infections. Data on the long-term outcomes of infants exposed to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection in the antenatal or neonatal period are limited. This study aimed to investigate potential neurological complications in children with antenatal or neonatal exposure to SARS-CoV-2. Method: In this prospective cross-sectional study, infants and toddlers with a history of antenatal or neonatal SARS-CoV-2 exposure underwent neurological evaluation by a pediatric neurologist. Results: Of 31 children (19 males, median age 9.3 months) included in the study, maternal coronavirus disease-2019 (COVID-19) diagnosis was made in the first trimester of pregnancy in 1, the second trimester in 3, and the third trimester in 25 children. Two children were diagnosed with COVID-19 in the neonatal period, and 3 children with maternal COVID-19 diagnosis during pregnancy were also diagnosed with COVID-19 neonatally. On neurological examination, hypotonia and motor/social delays were observed in 1, microcephaly in 2, and macrocephaly in 1 child. Of the 8 children evaluated with magnetic resonance imaging, 1 had findings consistent with Joubert syndrome and the others were normal. All infants passed the standard auditory brainstem response test. The only ocular abnormalities detected were retinopathy of prematurity (stage 3) in 1 infant and poor eye contact and object tracking in the child with Joubert syndrome. Conclusion: Our study suggests that neurological development is mostly favorable in infants and toddlers exposed to SARS-CoV-2 in the antenatal or neonatal period.

Introduction: Despite the developments in pharmacologic treatments, traditional and complementary therapies have recently gained popularity in our country, as well as around the world. Aim: To question complementary and alternative medicine practices CAMP during clinical visits of pediatric neurology patients, to raise awareness of families and patients about the use of complementary and alternative medicine, and to prevent possible negative interactions. Methods: This prospective survey study was conducted with the parents of 300 pediatric patients aged between 6 months and 18 years, who were being treated at the Child Neurology Clinic between March 1st and May 30th, 2020. For the study, 360 patients’ parents who came to the Pediatric Neurology clinic for treatment were randomly selected, and a face-to-face survey lasting 2 minutes was conducted with 300 patients’ parents who agreed to participate in the study. This study was approved with the decision number E-20-12-62 at the meeting dated 21.12.2020 of the Clinical Research Ethics Committee of SBU Ankara Dr Sami Ulus Gynecology and Childhood Health and Diseases Training and Research Hospital. Results: Three hundred parents (56% women) participated in the study. Just over half (55.3%) of the patients were followed up with a diagnosis of epilepsy, 56.6% of the parents stated that they had used traditional and complementary therapy methods before, 43.4% stated that they did not use it, 46.54% stated that they used prayer and 23,9% used vitamin methods, respectively. Conclusion: In neurologic diseases, parents use traditional and complementary therapies as treatment methods, creating an alternative to modern medicine. Families and patients should be informed by investigating the reasons and frequency of using traditional and complementary therapies, raising the awareness of parents, and determining the possible harm caused by traditional and complementary therapies.