428 results on '"Evers M"'
Search Results
2. How signatures of quasifission evolve in reactions forming Curium
- Author
-
Williams E., Hinde D. J., Dasgupta M., du Rietz R., Carter I. P., Evers M., Luong D. H., McNeil S. D., Rafferty D. C., Ramachandran K., and Wakhle A.
- Subjects
Physics ,QC1-999 - Abstract
Quasifission, a fission-like reaction outcome in which no compound nucleus forms, is an important competitor to fusion in reactions used for super-heavy element formation. The precise mechanisms driving the competition between quasifission and fusion are poorly understood. To explore the influence reaction parameters have on quasifission probabilities, an investigation into the evolution of quasifission signatures as a function of entrance channel parameters is required. Using the Australian National University’s 14UD tandem accelerator and CUBE detector for two-body fission studies, measurements were made for a diverse range of reactions forming isotopes of Curium. Observables known to reveal signs of quasifission—namely mass ratio spectra, mass-angle distributions, and angular anisotropies—were extracted. Evidence of quasifission was observed in all reactions, but the observables showing evidence of quasifission were not the same for all reactions. A link between this evolution and reaction timescales will be discussed.
- Published
- 2015
- Full Text
- View/download PDF
3. Comparing Experimental and Theoretical Quasifission Mass Angle Distributions
- Author
-
Wakhle A., Simenel C., Hinde D.J., Dasgupta M., Evers M., Luong D.H., and du Rietz R.
- Subjects
Physics ,QC1-999 - Abstract
We examined the 40Ca + 238U reaction experimentally using the Mass-Angle Distribution (MAD) technique and within the Time Dependent Hartree Fock (TDHF) theory, using the TDHF3D code. A new, TDHF based approach has been developed to construct mass distributions as well. The results revealed that the orientation of the heavy deformed prolate nucleus plays a major role in the reaction outcome. It was found that aligned collisions lead to quasifission and short contact times of 5-10 zs, whilst anti-aligned collisions lead to longer contact times (> 23 zs). TDHF accurately predicted the presence of quasifission and the average mass splits in this reaction. The influence of shell effects around 208Pb in the calculated quasifission characteristics was observed in both experiment and theory.
- Published
- 2015
- Full Text
- View/download PDF
4. Dynamical approach to heavy ion-induced fission
- Author
-
Jeung D.Y., Williams E., Hinde D. J., Dasgupta M., du Rietz R., Evers M., Lin C.J., Luong D.H., Simenel C., and Wakhle A.
- Subjects
Physics ,QC1-999 - Abstract
Deep inelastic collisions (DICs) can compete strongly with fusion in collisions of heavy nuclei. However, standard coupled-channels calculations do not take DIC processes into account. As a result, calculations have been shown to overestimate the fusion cross-sections, resulting in a discrepancy between experimental data and theoretical calculations, particularly at energies above the fusion barrier. To investigate this discrepancy, we conducted a series of experiments using the ANU 14UD tandem accelerator and the CUBE 2-body fission spectrometer to examine the competition between transfer/DIC and fusion. In particular, fusion-fission and 3-body fission yields have been extracted for 34S + 232Th and 40Ca + 232Th systems. This work shows that the transfer-fission probability is enhanced relative to fusion-fission for 40Ca + 232Th, when compared to 34S+ 232Th. It is suggested that the enhancement of this DIC process in 40Ca + 232Th is linked to an increase in the density overlap of the colliding nuclei as a function of the charge product and contributes to fusion hindrance.
- Published
- 2015
- Full Text
- View/download PDF
5. Many-body Quantum Reaction Dynamics near the Fusion Barrier
- Author
-
Dasgupta M., Luong D.H., Hinde D.J., and Evers M.
- Subjects
Physics ,QC1-999 - Abstract
The understanding of quantum effects in determining nuclear reaction outcomes is evolving as improved experimental techniques reveal new facets of interaction dynamics. Whilst the phenomenon of coupling-enhanced quantum tunnelling is understood to arise due to quantum superposition, the observed inhibition of fusion at energies well below the barrier is not yet quantitatively understood. Collisions involving weakly-bound nuclei, which have low energy thresholds against breakup, present further challenges. Recent coincidence measurements for reactions of weakly bound stable nuclei have not only provided a complete picture of the physical mechanisms triggering breakup, but have also shown how information on reaction dynamics occurring on time-scales of ~zepto-seconds can be obtained experimentally. These new experimental findings demand major developments in quantum models of near-barrier nuclear reactions.
- Published
- 2014
- Full Text
- View/download PDF
6. Mass-angle distributions
- Author
-
Hinde D.J., du Rietz R., Williams E., Simenel C., Lin C.J., Wakhle A., Cook K.J., Dasgupta M., Evers M., and Luong D.H.
- Subjects
Physics ,QC1-999 - Abstract
Mass-angle distributions carry detailed information on the characteristics of quasifission, and thus of the dynamics of heavy element formation reactions. Recent experimental results are presented and discussed.
- Published
- 2014
- Full Text
- View/download PDF
7. Fission fragment mass distribution in the 13C+182W and 176Yb reactions
- Author
-
Ramachandran K., Hinde D.J., Dasgupta M., Williams E., Wakhle A., Luong D.H., Evers M., Carter I.P., and Das S.
- Subjects
Physics ,QC1-999 - Abstract
Shell effects can play a prominent role in fission fragment mass distributions. For lighter systems in the region of A~180-200, mass distributions were generally expected to be symmetric. However, a recent experiment showed that fission of 180Hg following electron capture of 180Tl leads to an asymmetric mass split. Recent calculations by various groups indicate that the mechanism of asymmetric fission could be very different in this mass region compared to the actinide region. To investigate the role of shell effects in this mass region, we have measured the fission fragment mass distribution for the 13C+182W,176Yb reactions forming the compound nuclei 195Hg and 189Os respectively, at lab bombarding energies of 60, 63 and 66 MeV using the CUBE detector setup located at the ANU Heavy Ion Accelerator Facility. The experimental data were fitted with single and double Gaussian distributions. The results indicate an asymmetric mass split for 195Hg, whereas for 189Os, the mass distribution is well fitted with a single Gaussian distribution.
- Published
- 2013
- Full Text
- View/download PDF
8. Nuclear Reaction Dynamics Research at the Australian National University
- Author
-
Hinde D. J., Dasgupta M., Carter I.P., Cook K.J., Evers M., Luong D.H., Ramachandran K., Rafferty D., Simenel C., Wakhle A., and Williams E.
- Subjects
Physics ,QC1-999 - Abstract
This contribution presents an overview of the research program in nuclear reaction dynamics at the Australian National University.
- Published
- 2013
- Full Text
- View/download PDF
9. Study of fusion reactions forming Cf nuclei
- Author
-
Khuyagbaatar J., Hinde D.J., du Rietz R., Carter I. P., Dasgupta M., Düllmann Ch.E., Evers M., Wakhle A., Williams E., and Yakushev A.
- Subjects
Physics ,QC1-999 - Abstract
The formation of a compound nucleus in different projectile and target combinations is a powerful method for investigating the fusion process. Recently, the dominance of quasi-fission over fusion-fission has been inferred for 34S+208Pb in comparison to 36S+206Pb; both reactions lead to the compound nucleus 242Cf*.The mass and angle distributions of the fission fragments from these reactions were studied in order to further investigate the presence of quasi-fission.
- Published
- 2013
- Full Text
- View/download PDF
10. Breakup mechanisms for 7Li + 197Au, 204Pb systems at sub-barrier energies
- Author
-
Luong D.H., Dasgupta M., Hinde D.J., du Rietz R., Rafiei R., Evers M., Lin C.J., Wakhle A., Ramachandran K., Carter I.P., and Diaz-Torres A.
- Subjects
Physics ,QC1-999 - Abstract
Coincidence measurements of breakup fragments were carried out for the 7Li + 197Au and 204Pb systems at sub-barrier energies. The mechanisms triggering breakup, and time-scales of each process, were identified through the reaction Q-values and the relative energy of the breakup fragments. Binary breakup of 7Li were found to be predominantly triggered by nucleon transfer, with p-pickup leading to 8Be → α + α decay being the preferred breakup mode. From the time-scales of each process, the coincidence yields were separated into prompt and delayed components, allowing the identification of breakup process important in the suppression of complete fusion of 7Li at above-barrier energies.
- Published
- 2013
- Full Text
- View/download PDF
11. Effect of the Use of an iPad on the Attention Span of a Child with Smith Magenis Syndrome: A Single Case Study
- Author
-
Rikken-Evers, M. T., Smith, K. D., and Sterkenburg, P. S.
- Abstract
Aims: To assess the effectiveness of iPad use on the attention span of a child with Smith Magenis Syndrome (n = 1), compared to attention span while working on the same tasks manually. Methods: An AB design with a baseline and an intervention phase was used. Three manual tasks were chosen for the baseline, which matched the participant's intellectual age by the Early Intervention Method: a jigsaw puzzle (six pieces), a shape sorter, and matching pictures. These same tasks were performed on an iPad during the intervention phase. Six baseline and nine intervention phase films were included in the analysis. The 15 films were independently scored "twice" by "two" observers: once to observe the types of distractions that occurred (such as standing up from the chair, calling the teacher, or turning around on the chair), and a second time to measure the effective working time. Results: iPad use led to a 45% decrease in the number of total distractions. The effective working time improved by 8% and showed a more consistent range compared to working on tasks manually. While task enjoyment was not directly measured, the observers and teachers agreed that working on the iPad appeared to be more enjoyable. Conclusions: In this single case study the participant showed that in his case iPad use can be effective in decreasing his distractions and therefore can improve his attention span. Enjoyment was higher while working with the iPad than performing tasks manually. This technology could therefore create more learning engagement for the participant, which could positively impact his behavior. Further research into iPad implementation for children with intellectual disabilities, poor fine motor skills, and/or attention deficits is needed.
- Published
- 2022
- Full Text
- View/download PDF
12. Effects of nuclear structure on quasi-fission
- Author
-
Lin C. J., Evers M., Dasgupta M., Rietz R. du, Hinde D. J., Avez B., Simenel Cédric, Wakhle Aditya, and Luong D. H.
- Subjects
Physics ,QC1-999 - Abstract
The quasi-fission mechanism hinders fusion of heavy systems because of a mass flow between the reactants, leading to a re-separation of more symmetric fragments in the exit channel. A good understanding of the competition between fusion and quasi-fission mechanisms is expected to be of great help to optimize the formation and study of heavy and superheavy nuclei. Quantum microscopic models, such as the time-dependent Hartree-Fock approach, allow for a treatment of all degrees of freedom associated to the dynamics of each nucleon. This provides a description of the complex reaction mechanisms, such as quasi-fission, with no parameter adjusted on reaction mechanisms. In particular, the role of the deformation and orientation of a heavy target, as well as the entrance channel magicity and isospin are investigated with theoretical and experimental approaches.
- Published
- 2012
- Full Text
- View/download PDF
13. Applications of a 6.5T Superconducting Solenoidal Separator
- Author
-
Williams E., Wakhle A., Luong D.H., Lane G.J., Evers M., Weisser D.C., Lobanov N., Kibedi T., Carter I.P., Horsley A.J., Brown M.L., Rafiei R., Rodriguez M.D., Dasgupta M., and Hinde D.J.
- Subjects
Physics ,QC1-999 - Abstract
A 6.5 Tesla superconducting gas-filled solenoid (SOLITAIRE) has been developed at the Heavy Ion Accelerator Facility at the ANU as a reaction product separator. Key features of the device allowing its application for precise measurement of heavy ion fusion cross sections are described. The physical separation of beam particles and the high efficiency (~80%) transport of heavy ion fusion products open up applications in nuclear structure physics, and in materials science. Finally, the developments to allow its application to providing beams of light radioactive isotopes (SOLEROO) are described.
- Published
- 2012
- Full Text
- View/download PDF
14. Sub-barrier transfer in 16O+208Pb and 32S+208Pb and its role in understanding the suppression of fusion
- Author
-
Hinde D. J., Simenel C., Evers M., and Dasgupta M.
- Subjects
Physics ,QC1-999 - Abstract
A detailed analysis of the projectile-like fragments detected at backward angles in the reactions 16O, 32S+208Pb at energies below the fusion barrier is presented. Excitation functions corresponding to nucleon transfer with ΔZ = 1 and ΔZ = 2 were extracted, indicating surprisingly large absolute probabilities at sub-barrier energies. A comparison of 2p transfer probabilities with time-dependent Hartree-Fock calculations suggests strong pairing correlations between the two protons. Excitation energies in the projectile-like fragments up to ~ 15MeV for the 16O and ~ 25MeV for 32S-induced reactions demonstrate the population of highly excited states in the residual nuclei, indicating substantial dissipation of kinetic energy. These highly inelastic (large excitation energies) and complex (correlated few-nucleon transfer) processes may be closely related to the depletion of fusion through tunnelling at sub-barrier energies.
- Published
- 2012
- Full Text
- View/download PDF
15. Reconstructing breakup at sub-barrier energies
- Author
-
du Rietz R., Rafiei R., Evers M., Dasgupta M., Hinde D.J., and Luong D. H.
- Subjects
Physics ,QC1-999 - Abstract
Using a position sensitive detector array, back-angle coincidence measurements of breakup fragments at sub-barrier energies has enabled the complete characterisation of the breakup processes in the reactions of 6,7Liw ith 208PbB. reakup processes and their time-scales are identified through the reaction Q-values and the relative energy of the captured breakup fragments. The majority of breakup processes fast enough (~10-22s) to affect fusion are triggered by transfer of a neutron from 6Li, and of a proton to 7Li. These breakup mechanisms should therefore have a major contribution to the ~30% suppression of complete fusion observed at above-barrier energies.
- Published
- 2012
- Full Text
- View/download PDF
16. Determination of the angular distribution of evaporation residues following transmission through the superconducting solenoidal separator SOLITAIRE
- Author
-
Williams E., Wakhle A., Luong D.H., Evers M., Hinde D.J., Dasgupta M., Brown M.L., and Carter I.P.
- Subjects
Physics ,QC1-999 - Abstract
A highly efficient superconducting solenoidal fusion product separator has been developed at the Australian National University in order to enable separation and detection of evaporation residues following heavy-ion collisions. The determination of absolute fusion cross-sections requires an accurate knowledge of the transmission efficiency of evaporation residues through the superconducting solenoid, which in turn depends on the angular distribution of evaporation residues exiting the target. Two methods have been developed to extract the angular distributions using the radial distribution and the velocity distribution of the evaporation residues exiting the solenoid. The angular distributions are compared with existing direct measurements of evaporation residue angular distributions.
- Published
- 2012
- Full Text
- View/download PDF
17. Quasifission and Shell Effects in Reactions Forming 266Sg
- Author
-
Luong D.H., Rafiei R., Simenel C., Evers M., Hinde D.J., Dasgupta M., du Rietz R., and Wakhle A.
- Subjects
Physics ,QC1-999 - Abstract
The role of shell effects in reactions forming the heavy element 266Sg was investigated using the Mass Angle Distribution technique. For the 34S + 232Th reaction the doubly magic shell closure at 208Pb was found to strongly influence asymmetric quasifission, the exit channel at sub barrier energies. The evolution of the dinuclear system is arrested as it passes through this mass region. Mass splits corresponding to AL/AH ≈ 58/208 are seen for a large range of angles indicating a long timescale for this process. The more mass asymmetric 28Si + 238U reaction has a much smaller quasifission cross section. Therefore the shell effects around 208Pb are not dominant here.
- Published
- 2012
- Full Text
- View/download PDF
18. A complete picture of the breakup in 6,7Li-induced reactions
- Author
-
du Rietz R., Rafiei R., Evers M., Dasgupta M., Hinde D.J., and Luong D.H.
- Subjects
Physics ,QC1-999 - Abstract
Experiments with weakly-bound nuclei have demonstrated that breakup significantly affects the reaction outcomes. Coincidence measurements of breakup fragments at sub-barrier energies, using a position sensitive back-angle detector array covering 117° to 167° , have enabled the complete characterisation of the breakup processes in the reactions of the weakly-bound 6,7Li with 208Pb. The timescales of different breakup processes were also extracted from the fragments kinematics, enabling a clear characterization of prompt and delayed breakup. The majority of these prompt breakup events are triggered by n-stripping for 6Li, and p-pickup for 7Li. The demonstration that the reaction dynamics and outcomes can be significantly determined not only by the properties of the two colliding nuclei, but by the ground-state and excited state properties of their neighbours, is a key insight for understanding and predicting reactions of weakly-bound nuclei near the limits of nuclear existence.
- Published
- 2011
- Full Text
- View/download PDF
19. (Multi-)nucleon transfer in the reactions 16O, 32S+208Pb
- Author
-
Hinde D.J., Dasgupta M., Evers M., and Simenel C.
- Subjects
Physics ,QC1-999 - Abstract
A detailed analysis of the projectile-like fragments detected at backward angles in the reactions 16O,32 S+208Pb at energies below the fusion barrier is presented. Excitation functions corresponding to nucleon transfer with ∆Z = 1 and ∆Z = 2 were extracted, indicating surprisingly large absolute probabilities at subbarrier energies. A comparison of 2p transfer probabilities with time-dependent Hartree-Fock calculations suggests strong pairing correlations between the two protons. Excitation energies in the projectile-like fragments ~15 MeV and ~25 MeV for the 16O and 32S-induced reactions, respectively, indicate the population of highly excited states in the residual nuclei. A comparison with expected optimum Q-values suggests large losses in kinetic energy of the projectile-like fragments. These highly inelastic (large excitation energies) and complex (correlated few-nucleon transfer) processes may be closely related to the depletion of fusion through tunnelling at sub-barrier energies.
- Published
- 2011
- Full Text
- View/download PDF
20. Willingness to vaccinate children against COVID-19 declined during the pandemic
- Author
-
Goldman, R.D., Hart, R.J., Bone, J.N., Seiler, M., Olson, P.G., Keitel, K., Manzano, S., Gualco, G., Krupik, D., Schroter, S., Weigert, R.M., Chung, S., Thompson, G.C., Muhammad, N., Shah, P., Gaucher, N.O., Hou, M., Griffiths, J., Lunoe, M.M., Evers, M., Pharisa Rochat, C., Nelson, C.E., Gal, M., and Baumer-Mouradian, S.H.
- Published
- 2023
- Full Text
- View/download PDF
21. Polarized phonons carry angular momentum in ultrafast demagnetization
- Author
-
Tauchert, S. R., Volkov, M., Ehberger, D., Kazenwadel, D., Evers, M., Lange, H., Donges, A., Book, A., Kreuzpaintner, W., Nowak, U., and Baum, P.
- Published
- 2022
- Full Text
- View/download PDF
22. Requirements for home-based upper extremity rehabilitation using wearable motion sensors for stroke patients: a user-centred approach.
- Author
-
Langerak, A. J., Regterschot, G. R. H., Selles, R. W., Meskers, C. G. M., Evers, M., Ribbers, G. M., van Beijnum, B. J. F., and Bussmann, J. B. J.
- Subjects
PHYSICAL therapy ,HOME care services ,ARM ,RESEARCH funding ,EXERCISE therapy ,FUNCTIONAL assessment ,WEARABLE technology ,TELEREHABILITATION ,DESCRIPTIVE statistics ,STROKE rehabilitation ,LITERATURE reviews ,STROKE patients ,STAKEHOLDER analysis - Abstract
Telerehabilitation systems have the potential to enable therapists to monitor and assist stroke patients in achieving high-intensity upper extremity exercise in the home environment. We adopted an iterative user-centred approach, including multiple data sources and meetings with end-users and stakeholders to define the user requirements for home-based upper extremity rehabilitation using wearable motion sensors for subacute stroke patients. We performed a requirement analysis consisting of the following steps: 1) context & groundwork; 2) eliciting requirements; 3) modelling & analysis; 4) agreeing requirements. During these steps, a pragmatic literature search, interviews and focus groups with stroke patients, physiotherapists and occupational therapists were performed. The results were systematically analysed and prioritised into "must-haves", "should-haves", and "could-haves". We formulated 33 functional requirements: eighteen must-have requirements related to blended care (2), exercise principles (7), exercise delivery (3), exercise evaluation (4), and usability (2); ten should-haves; and five could-haves. Six movement components, including twelve exercises and five combination exercises, are required. For each exercise, appropriate exercise measures were defined. This study provides an overview of functional requirements, required exercises, and required exercise measures for home-based upper extremity rehabilitation using wearable motion sensors for stroke patients, which can be used to develop home-based upper extremity rehabilitation interventions. Moreover, the comprehensive and systematic requirement analysis used in this study can be applied by other researchers and developers when extracting requirements for designing a system or intervention in a medical context. This study provides an extensive overview of user requirements for home-based upper extremity rehabilitation using wearable motion sensors in stroke patients. These requirements can be used as a basis for developing home-based UE telerehabilitation interventions. Including these requirements may facilitate the clinical implementation of such telerehabilitation systems. The comprehensive and systematic approach used in this sudy can be applied by other researchers and developers when extracting requirements for designing a system or intervention in a medical context. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
23. Participatory approaches for disaster risk governance? Exploring participatory mechanisms and mapping to close the communication gap between population living in flood risk areas and authorities in Nova Friburgo Municipality, RJ, Brazil
- Author
-
Bustillos Ardaya, A., Evers, M., and Ribbe, L.
- Published
- 2019
- Full Text
- View/download PDF
24. What influences disaster risk perception? Intervention measures, flood and landslide risk perception of the population living in flood risk areas in Rio de Janeiro state, Brazil
- Author
-
Bustillos Ardaya, A., Evers, M., and Ribbe, L.
- Published
- 2017
- Full Text
- View/download PDF
25. Long-term (180-day) outcomes in critically ill patients with COVID-19 in the REMAP-CAP randomized clinical trial
- Author
-
Florescu, S, Stanciu, D, Zaharia, M, Kosa, A, Codreanu, D, Kidwai, A, Masood, S, Kaye, C, Coutts, A, MacKay, L, Summers, C, Polgarova, P, Farahi, N, Fox, E, McWilliam, S, Hawcutt, D, Rad, L, O’Malley, L, Whitbread, J, Jones, D, Dore, R, Saunderson, P, Kelsall, O, Cowley, N, Wild, L, Thrush, J, Wood, H, Austin, K, Bélteczki, J, Magyar, I, Fazekas, Á, Kovács, S, Szőke, V, Donnelly, A, Kelly, M, Smyth, N, O’Kane, S, McClintock, D, Warnock, M, Campbell, R, McCallion, E, Azaiz, A, Charron, C, Godement, M, Geri, G, Vieillard-Baron, A, Johnson, P, McKenna, S, Hanley, J, Currie, A, Allen, B, McGoldrick, C, McMaster, M, Mani, A, Mathew, M, Kandeepan, R, Vignesh, C, TV, B, Ramakrishnan, N, James, A, Elvira, E, Jayakumar, D, Pratheema, R, Babu, S, Ebenezer, R, Krishnaoorthy, S, Ranganathan, L, Ganesan, M, Shree, M, Guilder, E, Butler, M, Cowdrey, K-A, Robertson, M, Ali, F, McMahon, E, Duffy, E, Chen, Y, Simmonds, C, McConnochie, R, O’Connor, C, El-Khawas, K, Richardson, A, Hill, D, Commons, R, Abdelkharim, H, Saxena, M, Muteithia, M, Dobell-Brown, K, Jha, R, Kalogirou, M, Ellis, C, Krishnamurthy, V, O’Connor, A, Thurairatnam, S, Mukherjee, D, Kaliappan, A, Vertue, M, Nicholson, A, Riches, J, Maloney, G, Kittridge, L, Solesbury, A, Ramos, A, Collins, D, Brickell, K, Reid, L, Smyth, M, Breen, P, Spain, S, Curley, G, McEvoy, N, Geoghegan, P, Clarke, J, Silversides, J, McGuigan, P, Ward, K, O’Neill, A, Finn, S, Wright, C, Green, J, Collins, É, Knott, C, Smith, J, Boschert, C, Slieker, K, Ewalds, E, Sanders, A, Wittenberg, W, Geurts, H, Poojara, L, Sara, T, Nand, K, Reeve, B, Dechert, W, Phillips, B, Oritz-Ruiz de Gordoa, L, Affleck, J, Shaikh, A, Murray, A, Ramanan, M, Frakking, T, Pinnell, J, Robinson, M, Gledhill, L, Wood, T, Sanghavi, R, Bhonagiri, D, Ford, M, Parikh, HG, Avard, B, Nourse, M, McDonald, B, Edmunds, N, Hoiting, O, Peters, M, Rengers, E, Evers, M, Prinssen, A, Morgan, M, Cole, J, Hill, H, Davies, M, Williams, A, Thomas, E, Davies, R, Wise, M, Grimm, P, Soukup, J, Wetzold, R, Löbel, M, Starke, L, Lellouche, F, Lizotte, P, Declerq, P, Antoine, M, Stephanie, G, Jean-Pierre, E, François, B, Marion, B, Philippe, R, Pourcine, F, Monchi, M, Luis, D, Mercier, R, Sagnier, A, Verrier, N, Caplin, C, Richecoeu, J, Combaux, D, Siami, S, Aparicio, C, Vautier, S, Jeblaoui, A, Lemaire-Brunel, D, D'Aragon, F, Carbonneau, E, Leblond, J, Plantefeve, G, Leparco, C, Contou, D, Fartoukh, M, Courtin, L, Labbe, V, Voiriot, G, Salhi, S, Chassé, M, Carrier, F, Boumahni, D, Benettaib, F, Ghamraoui, A, Sement, A, Gachet, A, Hanisch, A, Haffiane, A, Boivin, A-H, Barreau, A, Guerineau, E, Poupblanc, S, Egreteau, P, Lefevre, M, Bocher, S, Le Loup, G, Le Guen, L, Carn, V, Bertel, M, Antcliffe, D, Templeton, M, Rojo, R, Coghlan, P, Smee, J, Barker, G, Finn, A, Kreb, G, Hoff, U, Hinrichs, C, Nee, J, Mackay, E, Cort, J, Whileman, A, Spencer, T, Spittle, N, Beavis, S, Padmakumar, A, Dale, K, Hawes, J, Moakes, E, Gascoyne, R, Pritchard, K, Stevenson, L, Cooke, J, Nemeth-Roszpopa, K, Gauli, B, Bastola, S, Muller, G, Nay, M-A, Kamel, T, Benzekri, D, Jacquier, S, Runge, I, Mathonnet, A, Barbier, F, Bretagnol, A, Carter, J, Van Der Heyden, K, Mehrtens, J, Morris, A, Morgan, S, Burke, T, Mercier, E, Chartier, D, Salmon, C, Dequin, P-F, Garot, D, Bellemare, D, Cloutier, È, Daher, R, Costerousse, O, Boulanger, M-C, Couillard-Chénard, É, Lauzier, F, Francoeur, C, Francois, B, Gay, A, Anne-Laure, F, Ramali, M, HC, O, Ghosh, A, Osagie, R, Arachchige, M, Hartley, M, Cheung, W, Wong, H, Seigne, P, Eustace, J, O'Callaghan, A-M, O'Brien, F, Bamford, P, Reid, A, Cawley, K, Faulkner, M, Pickering, C, Raj, A, Tsinaslanidis, G, Khade, R, Agha, G, Sekiwala, R, Smith, T, Brewer, C, Gregory, J, Limb, J, Cowton, A, O’Brien, J, Postlethwaite, K, Malakouti, S, Music, E, Ricketts, D, King, A, Clermont, G, Bart, R, Mayr, F, Schoenling, A, Andreae, M, Shetty, V, Brant, E, Malley, B, Donadee, C, Sackrowitz, R, Weissman, A, Yealy, D, Barton, D, Talia, N, Nikitas, N, Wells, C, Lankester, L, McMillan, H, Van den Oever, H, Kruisdijk-Gerritsen, A, Haidar, G, Bain, W, Barbash, I, Fitzpatrick, M, Franz, C, Kitsios, G, Moghbeli, K, Rosborough, B, Shah, F, Suber, T, Pulletz, M, Williams, P, Birch, J, Wiseman, S, Horton, S, Alegria, A, Turki, S, Elsefi, T, Crisp, N, Allen, L, Truman, N, Smith, M, Chukkambotla, S, Goddard, W, Duberley, S, Khan, M, Kazi, A, Simpson, J, Duke, G, Chan, P, Carter, B, Hunter, S, Voigt, I, Schueler, R, Blank, E, Hüning, V, Steffen, M, Goralski, P, Litton, E, Regli, A, Pellicano, S, Palermo, A, Eroglu, E, Bihari, S, Laver, RD, Jin, X, Brown, J, McIntyre, J, French, C, Bates, S, Towns, M, Yang, Y, McGain, F, McCullagh, I, Cairns, T, Hanson, H, Patel, B, Clement, I, Evetts, G, Touma, O, Holland, S, Hodge, C, Taylor, H, Alderman, M, Barnes, N, Da Rocha, J, Smith, C, Brooks, N, Weerasinghe, T, Sinclair, J-A, Abusamra, Y, Doherty, R, Cudlipp, J, Singh, R, Yu, H, Daebis, A, Ng, C, Kendrick, S, Saran, A, Makky, A, Greener, D, Rowe-Leete, L, Edwards, A, Bland, Y, Dolman, R, Foster, T, Laffey, J, McNicholas, B, Scully, M, Casey, S, Kernan, M, Brennan, A, Rangan, R, Tully, R, Corbett, S, McCarthy, A, Duffy, O, Burke, D, Linnett, V, Sanderson, A, Ritzema, J, Wild, H, Lucas, R, Marriott, Y, Andric, Z, Cviljevic, S, Br, R, Zapalac, M, Mirković, G, Khare, D, Pinder, M, Gopinath, A, Kannan, T, Dean, S, Vanmali, P, Depuydt, P, De Waele, J, De Bus, L, Fierens, J, Bracke, S, Vermassen, J, Vermeiren, D, Pugh, R, Lean, R, Qiu, X, Scanlan, J, Evans, A, Davies, G, Lewis, J, Plesnikova, Y, Khoud, A, Coetzee, S, Puxty, K, Cathcart, S, Rimmer, D, Bagot, C, Scott, K, Martin, L, Yusuff, H, Isgro, G, Brightling, C, Bourne, M, Craner, M, Boyles, R, Alexander, B, Roberts, T, Nelli, A, Rosenstein-Sisson, R, Speyer, R, Pech, Y, McCullough, J, Tallott, M, Vazquez-Grande, G, Marten, N, Liu, T, Siddiqui, A, Khanal, S, Amatya, S, Szakmany, T, Cherian, S, Williams, G, James, C, Waters, A, Prout, R, Stedman, R, Davies, L, Pegler, S, Kyeremeh, L, Moorhouse, L, Arbane, G, Marotti, M, Bociek, A, Campos, S, Van Nieuwkoop, K, Ottens, T, Visser, Y, Van den Berg, L, Van der Kraan-Donker, A, Brett, S, Arias, S, Hall, R, Paneru, H, Koirala, S, Paudel, P, Wilson, M, Vaara, S, Pettilä, L, Heinonen, J, Pettilä, V, Jain, S, Gupta, A, Holbrook, C, Antoine, P, Meziani, F, Allam, H, Cattelan, J, Clere-Jehl, R, Helms, J, Kummerlen, C, Merdji, H, Monnier, A, Rahmani, H, Studer, A, Schneider, F, Castelain, V, Morel, G, L’Hotellier, S, Ochin, E, Vanjak, C, Rouge, P, Bendjemar, L, Albert, M, Serri, K, Cavayas, A, Duplaix, M, Williams, V, Catorze, NJTADS, Pereira, TNAL, Ferreira, RMC, Bastos, JMPS, Batista, TMO, Badie, J, Berdaguer, F, Malfroy, S, Mezher, C, Bourgoin, C, Moneger, G, Bouvier, E, Muñoz-Bermúdez, R, Marin-Corral, J, Degracia, A, Gómez, F, López, M, Aceto, R, Aghemo, A, Badalamenti, S, Brunetta, E, Cecconi, M, Ciccarelli, M, Constantini, E, Greco, M, Folci, M, Selmi, C, Voza, A, Henning, J, Bonner, S, Hugill, K, Cirstea, E, Wilkinson, D, Jones, J, Altomy, M, Karlikowski, M, Sutherland, H, Wilhelmsen, E, Woods, J, North, J, Pletz, M, Hagel, S, Ankert, J, Kolanos, S, Bloos, F, Simons, K, Van Zuylen, T, Bouman, A, Kumar, N, Panwar, R, Poulter, A-L, Sunkara, K, Szigligeti, G, Leszkoven, J, Rochwerg, B, Karachi, T, Oczkowski, S, Centofanti, J, Millen, T, Sundaran, D, Hollos, L, Turns, M, Walsh, J, Al Qasim, E, Alswaidan, L, Hegazy, M, Arishi, H, Al Amri, A, AlQahtani, S, Naidu, B, Tlayjeh, H, Hussain, S, Al Enezi, F, Abdukahil, SA, Hopkins, P, Noble, H, O’Reilly, K, Mehta, R, Wong, O, Makanju, E, Rao, D, Sikondari, N, Saha, S, Corcoran, E, Pappa, E, Cockrell, M, Donegan, C, Balaie, M, Nickoleit-Bitzenberger, D, Schaaf, B, Meermeier, W, Prebeg, K, Azzaui, H, Hower, M, Brieger, K-G, Elender, C, Sabelhaus, T, Riepe, A, Akamp, C, Kremling, J, Klein, D, Landsiedel-Mechenbier, E, Laha, S, Verlander, M, Jha, A, Megarbane, B, Voicu, S, Deye, N, Malissin, I, Sutterlin, L, Mrad, A, Lehalleur, A, Naim, G, Nguyen, P, Ekhérian, J-M, Boué, Y, Sidéris, G, Vodovar, D, Guérin, E, Grant, C, Brain, M, Mineall, S, Paramasivam, E, Wilby, E, Ogg, B, Howcroft, C, Aspinwall, A, Charlton, S, Gould, R, Mistry, D, Awan, S, Bedford, C, Carr-Wilkinson, J, Hall, A, Gardiner-Hill, C, Maloney, C, Brunskill, N, Watchorn, O, Hardy, C, Qureshi, H, Flint, N, Nicholson, S, Southin, S, Ghattaoraya, A, Harding, D, O’Halloran, S, Collins, A, Smith, E, Trues, E, Borgatta, B, Turner-Bone, I, Reddy, A, Wilding, L, Wilson, C, Surti, Z, Aneman, A, Miller, J, White, H, Estensen, K, Morrison, L, Sutton, J, Cooper, M, Warnapura, L, Agno, R, Sathianathan, P, Shaw, D, Ijaz, N, Spong, A, Sabaretnam, S, Burns, D, Lang, E, Tate, M, Fischer, R, Biradar, V, Soar, N, Golden, D, Davey, M, Seaman, R, Osborne, A, Bannard-Smith, J, Clark, R, Birchall, K, Henry, J, Pomeroy, F, Quayle, R, Wylie, K, Sukuraman, A, John, M, Sibin, S, Leditschke, A, Finnis, M, Jongebloed, K, Khwaja, K, Campisi, J, Van Vonderen, M, Pietersma, M, Vrolijk, L, Kampschreur, L, Van Gulik, L, Makowski, A, Misztal, B, Haider, S, Liao, A, Squires, R, Oborska, A, Kayani, A, Kalchko-Veyssal, S, Prabakaran, R, Hadebe, B, KalchkoVeyssal, S, Williams, T, Song, R, Morpeth, S, Lai, V, Habraken, H, Stewart, R, Mwaura, E, Mew, L, Wren, L, Willams, F, Sutherland, S-B, Rebello, R, Shehabi, Y, Al-Bassam, W, Hulley, A, Kadam, U, Sathianathan, K, Innes, R, Doble, P, Graham, L, Shovelton, C, Dean, T, Salahuddin, N, Aryal, D, Koirala, K, Rai, N, Luitel, S, Seppelt, I, Whitehead, C, Lowrey, J, Gresham, R, Masters, K, Hamlyn, V, Hawkins, N, Roynon-Reed, A, Cutler, S, Lewis, S, Lazaro, J, Newman, T, Aravindan, L, Asghar, A, Bartholomew, J, Bayne, M, Beddows, S, Birch, C, Brend, M, Byrne, R, Campbell, D, Campbell, H, Chambers, E, Clinton, A, Collins, J, Crawshaw, S, Dawson, LA, Donaldson, K, Drake, C, Dyas, S, Ellis, Y, Gilmour, K, Goodwin, J, Halden, S, Hall, AS, Hanson, J, Harper, H, Harrison, S, Hayes, A, Hodgson, H, Hurford, S-A, Jackson, S, Levett, C, Lock, S, Lockett, T, Logan, M, Lomme, K, Luo, J, Marsh, E, Mguni, N, Monaghan, H, Murphy, S, Muzengi, N, Naz, M, O'Kell, E, Oliver, A, O'Reilly, J, Pearson, K, Porter, D, Potter, A, Rook, C, Rounds, C, Sheffield, J, Shirley, K, Siewersk, C, Skinner, T, Speight, H, Sutu, M, Unsworth, A, Van’t Hoff, W, Walker, S, Williams, H, Williamson, D, Williamson, JD, Duan, E, Tsang, J, Patterson, L, Austin, P, Chapman, S, Cabrelli, L, Fletcher, S, Nortje, J, Fottrell-Gould, D, Randell, G, Stammers, K, Healey, G, Pinto, M, Borrill, Z, Duncan, T, Ustianowski, A, Uriel, A, Eltayeb, A, Alfonso, J, Hey, S, Shaw, J, Fox, C, Lindergard, G, Charles, B, Blackledge, B, Connolly, K, Harris, J, Cuesta, J, Xavier, K, Purohit, D, Elhassan, M, Haldeos, A, Vincent, R, Abdelrazik, M, Jenkins, S, Ganesan, A, Kumar, R, Carter, D, Bakthavatsalam, D, Frater, A, Saleem, M, Everitt, R, Hacking, D, Zaman, M, Elmahi, E, Jones, A, Hall, K, Phillips, M, Terrill, L, Mills, G, Raithatha, A, Bauchmuller, K, Ryalls, K, Harrington, K, Bowler, H, Sall, J, Bourne, R, Gross, J, Massey, N, Adebambo, O, Long, M, Tony, K, Juffermans, N, Koopmans, M, Dujardin, R, Alderink, B, Rowland, M, Hutton, P, Bashyal, A, Davidson, N, Hird, C, Chhablani, M, Phalod, G, Kirkby, A, Archer, S, Netherton, K, Reschreiter, H, Camsooksai, J, Patch, S, Humphrey, C, Flynn, G, Harrington, C, Kruger, P, Walsham, J, Meyer, J, Harward, M, Jones, C, Sathe, S, Roche, L, Davies, E, Skinner, D, Gaylard, J, Newman, J, Pogson, D, Rose, S, Daly, Z, Brimfield, L, Nown, A, Parekh, D, Bergin, C, Bates, M, McGhee, C, Lynch, D, Bhandal, K, Tsakiridou, K, Bamford, A, Cooper, L, Whitehouse, T, Veenith, T, Forster, E, O'Connell, M, Sim, M, Hay, S, Henderson, S, Nygren, M, Valentine, E, Katary, A, Bell, G, Wilcox, L, Mataliotakis, M, Smith, P, Ali, M, Isguzar, A, Phull, M-K, Zaidi, A, Pogreban, T, Rosaroso, L, Harvey, D, Lowe, B, Meredith, M, Ryan, L, Schouten, J, Pickkers, P, Roovers, N, Klop-Riehl, M, Van der Eng, H, Sloots-Cuppen, S, Preijers, L, Van Oosten, N, Moine, P, Heming, N, Maxime, V, Bossard, I, Nicholier, T, Clair, B, Orlikowski, D, Bounab, R, Abdeladim, L, Baker, S, Duroux, M, Ratcliffe, M, Sy, E, Mailman, J, Lee, S, Gupta, C, Kassir, S, López, R, Rodríguez-Gómez, J, Cárcel, S, Carmona, R, De la Fuente, C, Rodriguez, M, Jan Hassing, R, Greven, F, Huijbens, D, Roebers, L, Verheij, H, Miles, H, Attokaran, A, Buehner, U, Williams, E, Chapman, M, O’Connor, S, Glasby, K, Rivett, J, Brown, N, Kutsogiannis, D, Thompson, P, Rooney, K, Rodden, N, Thomson, N, McGlynn, D, Abel, L, Gemmell, L, Sundaram, R, Hornsby, J, Walden, A, Keating, L, Frise, M, Rai, S, Bartley, S, Schuster-Bruce, M, Pitts, S, Miln, R, Purandare, L, Vamplew, L, Dempster, D, Gummadi, M, Dormand, N, Wang, S, Spivey, M, Bean, S, Burt, K, Moore, L, Hammonds, F, Richards, C, Campbell, L, Smyth, K, Day, C, Zitter, L, Benyon, S, Singh, J, Lynch, C, Mikusek, J, Deacon, B, Turner, K, Baker, E, Hickey, J, Champanerkar, S, Aitken, L, LewisProsser, L, Ahmad, N, Wiles, M, Willson, J, Grecu, I, Martin, J, Wrey Brown, C, Arias, A-M, Bevan, E, Westlake, S, Craven, T, Hope, D, Singleton, J, Clark, S, McCulloch, C, Biddie, S, Welters, I, Hamilton, D, Williams, K, Waugh, V, Mulla, S, Waite, A, Roman, J, Martinez, M, Johnston, B, Puthucheary, Z, Martin, T, Santos, F, Uddin, R, Fernandez, M, Seidu, F, Somerville, A, Pakats, M-L, Begum, S, Shahid, T, Presneill, J, Barge, D, Byrne, K, Janin, P, Yarad, E, Bass, F, Hammond, N, Vuylsteke, A, Chan, C, Victor, S, Waterson, S, McNamara, R, Boardman, M, Gattas, D, Buhr, H, Coles, J, Matsa, R, Gellamucho, M, Creagh-Brown, B, Marriot, C, Salberg, A, Zouita, L, Stone, S, Michalak, N, Donlon, S, Mtuwa, S, Mayangao, I, Verula, J, Burda, D, Harris, C, Jones, E, Bradley, P, Tarr, E, Harden, L, Piercy, C, Nolan, J, Kerslake, I, Cook, T, Simpson, T, Dalton, J, Demetriou, C, Mitchard, S, Ramos, L, White, K, Johnson, T, Headdon, W, Spencer, S, White, A, Howie, L, Reay, M, Watts, A, Traverse, E, Jennings, S, Anumakonda, V, Tuckwell, C, Harrow, K, Matthews, J, McGarry, K, Moore, V, Smith, L, Summerfield, A, Dark, P, Harvey, A, Doonan, R, McMorrow, L, Knowles, K, Pendlebury, J, Perez, J, Marsden, T, Taylor, M, Michael, A, Collis, M, Claxton, A, Habeichi, W, Horner, D, Slaughter, M, Thomas, V, Proudfoot, N, Keatley, C, Donnison, P, Casey, R, Irving, B, Matimba-Mupaya, W, Reed, C, Anthony, A, Trim, F, Cambalova, L, Robertson, D, Wilson, A, Hulme, J, Kannan, S, Kinney, F, Senya, H, Ratnam, V, Gill, M, Kirk, J, Shelton, S, Schweikert, S, Wibrow, B, Anstey, M, Rauniyar, R, Khoso, N, Asif, N, Taqdees, H, Frey, C, Scano, R, McKee, M, Murphy, P, Thomas, M, Worner, R, Faulkner, B, Gendall, E, Hayes, K, Blakemore, H, Borislavova, B, Deshpande, K, Van Haren, F, Konecny, P, Inskip, D, Tung, R, Hayes, L, Murphy, L, Neill, A, Reidy, B, O’Dwyer, M, Ryan, D, Ainscough, K, Hamilton-Davies, C, Mfuko, C, Abbass, H, Mandadapu, V, Leaver, S, Patel, K, Farnell-Ward, S, Saluzzio, R, Rawlins, S, Sicat, C, De Keulenaer, B, Ferrier, J, Fysh, E, Davda, A, Mevavala, B, Cook, D, Clarke, F, Banach, D, Fernández de Pinedo Artaraz, Z, Cabreros, L, Latham, V, Kruisselbrink, R, Brochard, L, Burns, K, Sandhu, G, Khalid, I, White, I, Croft, M, Holland, N, Pereira, R, Nair, P, Buscher, H, Reynolds, C, Newman, S, Santamaria, J, Barbazza, L, Homes, J, Smith, R, Zaki, A, Johnson, D, Garrard, H, Juhaz, V, Brown, L, Pemberton, A, Roy, A, Rostron, A, Woods, L, Cornell, S, Fowler, R, Adhikari, N, Kamra, M, Marinoff, N, Garrett, P, Murray, L, Brailsford, J, Fennessy, G, Mulder, J, Morgan, R, Pillai, S, Harford, R, Ivatt, H, Evans, D, Richards, S, Roberts, E, Bowen, J, Ainsworth, J, Kuitunen, A, Karlsson, S, Vahtera, A, Kiiski, H, Ristimäki, S, Albrett, J, Jackson, C, Kirkham, S, Tamme, K, Reinhard, V, Ellervee, A, Põldots, L, Rennit, P, Svitškar, N, Browne, T, Grimwade, K, Goodson, J, Keet, O, Callender, O, Udy, A, McCracken, P, Young, M, Board, J, Martin, E, Kasipandian, V, Patel, A, Allibone, S, Mary-Genetu, R, English, S, Watpool, I, Porteous, R, Miezitis, S, McIntyre, L, Brady, K, Vale, C, Shekar, K, Lavana, J, Parmar, D, Peake, S, Kurenda, C, Hormis, A, Walker, R, Collier, D, Kimpton, S, Oakley, S, Bhagani, S, De Neef, M, Garcia, S, Maharajh, A, Nandani, A, Dobson, J, Fernando, G, Eastgate, C, Gomez, K, Abdi, Z, Tatham, K, Jhanji, S, Black, E, Dela Rosa, A, Howle, R, Baikady, R, Drummond, A, Dearden, J, Philbin, J, Munt, S, Gopal, S, Pooni, J-S, Ganguly, S, Smallwood, A, Metherell, S, Naeem, A, Fagan, L, Ryan, E, Mariappa, V, Foulds, A, Revill, A, Bhattarai, B, De Jonge, E, Wigbers, J, Del Prado, M, Cremer, O, Mulier, J, Peters, A, Romberg, B, Schutgens, R, Troeman, D, Van Opdorp, M, Besten, H, Brakké, K, Barber, R, Hilldrith, A, Kluge, S, Nierhaus, A, Jarczak, D, Roedl, K, Kochanek, M, Rueß-Paterno, G, Mc-Kenzie, J, Eichenauer, D, Shimabukuro-Vornhagen, A, Wilcox, E, Del Sorbo, L, Abdelhady, H, Romagnuolo, T, Simpson, S, Maiden, M, Horton, M, Trickey, J, Krajinovic, V, Kutleša, M, Kotarski, V, Brohi, F, Jagannathan, V, Clark, M, Purvis, S, Wetherill, B, Brajković, A, Babel, J, Sever, H, Dragija, L, Kušan, I, Dushianthan, A, Cusack, R, De Courcy-Golder, K, Salmon, K, Burnish, R, Smith, S, Ruiz, W, Duke, Z, Johns, M, Male, M, Gladas, K, Virdee, S, Swabe, J, Tomlinson, H, Rohde, G, Grünewaldt, A, Bojunga, J, Petros, S, Kunz, K, Schütze, B, Weismann, D, Frey, A, Drayss, M, Goebeler, ME, Flor, T, Fragner, G, Wahl, N, Totzke, J, Sayehli, C, Hakak, S, Altaf, W, O'Sullivan, M, Murphy, A, Walsh, L, Rega La Valle, A, Bewley, J, Sweet, K, Grimmer, L, Johnson, R, Wyatt, R, Morgan, K, Varghese, S, Willis, J, Stratton, E, Kyle, L, Putensen, D, Drury, K, Skorko, A, Bremmer, P, Ward, G, Bassford, C, Sligl, W, Baig, N, Rewa, O, Bagshaw, S, Basile, K, Stavor, D, Burbee, D, McNamara, A, Wunderley, R, Bensen, N, Adams, P, Vita, T, Buhay, M, Scholl, D, Gilliam, M, Winters, J, Doherty, K, Berryman, E, Ghaffari, M, Marroquin, O, Quinn, K, Garrard, W, Kalchthaler, K, Beard, G, Skrtich, A, Bagavathy, K, Drapola, D, Bryan-Morris, K, Arnold, J, Reynolds, B, Hussain, M, Dunsavage, J, Saiyed, S, Hernandez, E, Goldman, J, Brown, C, Comp, S, Raczek, J, Morris, J, Vargas Jr., J, Weiss, D, Hensley, J, Kochert, E, Wnuk, C, Nemeth, C, Mowery, B, Hutchinson, C, Winters, L, McAdams, D, Walker, G, Minnier, T, Wisniewski, M, Mayak, K, McCreary, E, Bariola, R, Viehman, A, Daley, J, Lopus, A, Schmidhofer, M, Ambrosino, R, Keen, S, Toffalo, S, Stambaugh, M, Trimmer, K, Perri, R, Casali, S, Medva, R, Massar, B, Beyerl, A, Burkey, J, Keeler, S, Lowery, M, Oncea, L, Daugherty, J, Sevilla, C, Woelke, A, Dice, J, Weber, L, Roth, J, Ferringer, C, Beer, D, Fesz, J, Carpio, L, Colin, G, Zinzoni, V, Maquigneau, N, Henri-Lagarrigue, M, Pouplet, C, Reill, L, Distler, M, Maselli, A, Martynoga, R, Trask, K, Butler, A, Attwood, B, Parsons, P, Campbell, B, Smith, A, Page, V, Zhao, X, Oza, D, Abrahamson, G, Sheath, B, Young, P, Young, C, Lesona, E, Navarra, L, Cruz, R, Delaney, K, Aguilar-Dano, A, Gojanovic, M, Rhodes, J, Anderson, T, Morris, S, Nayyar, V, Bowen, D, Kong, J, Joy, J, Fuchs, R, Lambert, B, Tai, C, Thomas, A, Keen, A, Tierney, C, Omer, N, Bacon, G, Tridente, A, Shuker, K, Anders, J, Greer, S, Scott, P, Millington, A, Buchanan, P, Binnie, A, Powell, E, McMillan, A, Luk, T, Aref, N, Denmade, C, Sadera, G, Jacob, R, Hughes, D, Sterba, M, Geng, W, Digby, S, Southern, D, Reddy, H, Hulse, S, Campbell, A, Garton, M, Watkins, C, Smuts, S, Quinn, A, Simpson, B, McMillan, C, Finch, C, Hill, C, Cooper, J, Budd, J, Small, C, O’Leary, R, Collins, E, Holland, A, Alexander, P, Felton, T, Ferguson, S, Sellers, K, Ward, L, Yates, D, Birkinshaw, I, Kell, K, Scott, Z, Pearson, H, Hashmi, M, Hassan, N, Panjwani, A, Umrani, Z, Shaikh, M, Ain, Q, Kanwal, D, Van Bree, S, Bouw-Ruiter, M, Osinga, M, Van Zanten, A, McEldrew, R, Rashan, S, Singh, V, Azergui, N, Bari, S, Beltran, M, Brugman, C, Groeneveld, E, Jafarzadeh, M, Keijzer-Timmers, N, Kester, E, Koelink, M, Kwakkenbos-Craanen, M, Okundaye, C, Parker, L, Peters, S, Post, S, Rietveld, I, Scheepstra-Beukers, I, Schreuder, G, Smit, A, Brillinger, N, Markgraf, R, Eichinger, F, Doran, P, Anjum, A, Best-Lane, J, Barton, F, Miller, L, Richards-Belle, A, Saull, M, Sprinckmoller, S, Wiley, D, Darnell, R, Au, C, Lindstrum, K, Cheng, A, Forbes, A, Heritier, S, Trapani, T, Cuthbertson, B, Manoharan, V, Dondrop, A, Tolppa, T, Ehrmann, S, Hullegie, S, Povoa, P, Beasley, R, Daneman, N, McGloughlin, S, Paterson, D, Venkatesh, B, De Jong, M, Uyeki, T, Baillie, K, Netea, M, Orr, K, Patanwala, A, Tong, S, Cooper, N, Galea, J, Leavis, H, Ogungbenro, K, Patawala, A, Rademaker, E, Youngstein, T, Carrier, M, Fergusson, D, Hunt, B, Kumar, A, Laffan, M, Lother, S, Middeldorp, S, Stanworth, S, De Man, A, Masse, M-H, Abraham, J, Arnold, D, Begin, P, Charlewood, R, Chasse, M, Coyne, M, Daly, J, Gosbell, I, Harvala-Simmonds, H, MacLennan, S, McDyer, J, Menon, D, Pridee, N, Roberts, D, Thomas, H, Tinmouth, A, Triulzi, D, Walsh, T, Wood, E, Calfee, C, O’Kane, C, Shyamsundar, M, Sinha, P, Thompson, T, Young, I, Burrell, A, Ferguson, N, Hodgson, C, Orford, N, Phua, J, Baron, R, Epelman, S, Frankfurter, C, Gommans, F, Kim, E, Leaf, D, Vaduganathan, M, Van Kimmenade, R, Sanil, A, Van Beurden, M, Effelaar, E, Schotsman, J, Boyd, C, Harland, C, Shearer, A, Wren, J, Attanayaka, U, Darshana, S, Ishani, P, Udayanga, I, Higgins, AM, Berry, LR, Lorenzi, E, Murthy, S, McQuilten, Z, Mouncey, PR, Al-Beidh, F, Annane, D, Arabi, YM, Beane, A, Van Bentum-Puijk, W, Bhimani, Z, Bonten, MJM, Bradbury, CA, Brunkhorst, FM, Buzgau, A, Buxton, M, Charles, WN, Cove, M, Detry, MA, Estcourt, LJ, Fagbodun, EO, Fitzgerald, M, Girard, TD, Goligher, EC, Goossens, H, Haniffa, R, Hills, T, Horvat, CM, Huang, DT, Ichihara, N, Lamontagne, F, Marshall, JC, McAuley, DF, McGlothlin, A, McGuinness, SP, McVerry, BJ, Neal, MD, Nichol, AD, Parke, RL, Parker, JC, Parry-Billings, K, Peters, SEC, Reyes, LF, Rowan, KM, Saito, H, Santos, MS, Saunders, CT, Serpa-Neto, A, Seymour, CW, Shankar-Hari, M, Stronach, LM, Turgeon, AF, Turner, AM, Van de Veerdonk, FL, Zarychanski, R, Green, C, Lewis, RJ, Angus, DC, McArthur, CJ, Berry, S, Derde, LPG, Gordon, AC, Webb, SA, Lawler, PR, Comm REMAP-CAP Investigators, Apollo - University of Cambridge Repository, Intensive Care Medicine, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Raymond Poincaré [Garches], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Pittsburgh Foundation, PF, Amgen, Health Research Board, HRB: CTN 2014-012, Horizon 2020 Framework Programme, H2020: 101003589, Translational Breast Cancer Research Consortium, TBCRC, Canadian Institutes of Health Research, IRSC: 158584, Heart and Stroke Foundation of Canada, HSF, National Institute for Health and Care Research, NIHR, European Commission, EC, National Health and Medical Research Council, NHMRC: 1101719, APP194811, CS-2016-16-011, GNT2008447, RP-2015-06-18, Office of Health and Medical Research, OHMR, Health Research Council of New Zealand, HRC: 16/631, Eisai, Ministère des Affaires Sociales et de la Santé: PHRC-20-0147, Université Pierre et Marie Curie, UPMC, NIHR Imperial Biomedical Research Centre, BRC, Minderoo Foundation, Funding/Support : The Platform for European Preparedness Against (Re-) emerging Epidemics (PREPARE) consortium by the European Union, FP7-HEALTH-2013-INNOVATION-1 (#602525), the Rapid European COVID-19 Emergency Research response (RECOVER) consortium by the European Union’s Horizon 2020 research and innovation programme (#101003589), the Australian National Health and Medical Research Council (#APP1101719), the Australian Medical Research Future Fund (#APP2002132), the Health Research Council of New Zealand (#16/631), the Canadian Institutes of Health Research Strategy for Patient-Oriented Research Innovative Clinical Trials Program Grant (#158584) and the Canadian Institute of Health Research COVID-19 Rapid Research Funding (#447335), the UK National Institute for Health Research (NIHR) and the NIHR Imperial Biomedical Research Centre, the Health Research Board of Ireland (CTN 2014-012), the UPMC Learning While Doing Program, the Translational Breast Cancer Research Consortium, the French Ministry of Health (PHRC-20-0147), the Wellcome Trust Innovations Project (215522), the Minderoo Foundation, the EU Programme Emergency Support Instrument, the NHS Blood and Transplant Research and Development Programme, the Translational Breast Cancer Research Consortium, the NSW Office of Health and Medical Research, Amgen, Eisai, and the Pittsburgh Foundation. Dr Higgins is funded by an NHMRC Emerging Leadership Fellowship (GNT2008447). Dr McQuilten is funded by an NHMRC Emerging Leadership Fellowship (APP194811). Dr Gordon is funded by an NIHR Research Professorship (RP-2015-06-18) and Dr Shankar-Hari by an NIHR Clinician Scientist Fellowship (CS-2016-16-011). Dr Turgeon is the Chairholder of the Canada Research Chair in Critical Care Neurology and Trauma. Dr Lawler is supported by a career award from the Heart and Stroke Foundation of Canada., and European Project: 602525,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,PREPARE(2014)
- Subjects
Adult ,Male ,corticosteroid ,[SDV]Life Sciences [q-bio] ,Critical Illness ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,antiplatelet ,Lopinavir ,Adaptive platform trial randomized controlled trial intensive care, pneumonia COVID-19 antiplatelet immunoglobulin antiviral corticosteroid immune modulation anticoagulation ,All institutes and research themes of the Radboud University Medical Center ,Adrenal Cortex Hormones ,Humans ,anticoagulation ,intensive care, pneumonia ,COVID-19 Serotherapy ,Original Investigation ,Medicine(all) ,immune modulation ,Ritonavir ,SARS-CoV-2 ,COVID-19 ,Anticoagulants ,Bayes Theorem ,General Medicine ,Middle Aged ,antiviral ,Receptors, Interleukin-6 ,Adaptive platform trial ,randomized controlled trial ,Female ,Human medicine ,immunoglobulin ,Follow-Up Studies ,Hydroxychloroquine - Abstract
ImportanceThe longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown.ObjectiveTo determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes.Design, Setting, and ParticipantsPrespecified secondary analysis of an ongoing adaptive platform trial (REMAP-CAP) testing interventions within multiple therapeutic domains in which 4869 critically ill adult patients with COVID-19 were enrolled between March 9, 2020, and June 22, 2021, from 197 sites in 14 countries. The final 180-day follow-up was completed on March 2, 2022.InterventionsPatients were randomized to receive 1 or more interventions within 6 treatment domains: immune modulators (n = 2274), convalescent plasma (n = 2011), antiplatelet therapy (n = 1557), anticoagulation (n = 1033), antivirals (n = 726), and corticosteroids (n = 401).Main Outcomes and MeasuresThe main outcome was survival through day 180, analyzed using a bayesian piecewise exponential model. A hazard ratio (HR) less than 1 represented improved survival (superiority), while an HR greater than 1 represented worsened survival (harm); futility was represented by a relative improvement less than 20% in outcome, shown by an HR greater than 0.83.ResultsAmong 4869 randomized patients (mean age, 59.3 years; 1537 [32.1%] women), 4107 (84.3%) had known vital status and 2590 (63.1%) were alive at day 180. IL-6 receptor antagonists had a greater than 99.9% probability of improving 6-month survival (adjusted HR, 0.74 [95% credible interval {CrI}, 0.61-0.90]) and antiplatelet agents had a 95% probability of improving 6-month survival (adjusted HR, 0.85 [95% CrI, 0.71-1.03]) compared with the control, while the probability of trial-defined statistical futility (HR >0.83) was high for therapeutic anticoagulation (99.9%; HR, 1.13 [95% CrI, 0.93-1.42]), convalescent plasma (99.2%; HR, 0.99 [95% CrI, 0.86-1.14]), and lopinavir-ritonavir (96.6%; HR, 1.06 [95% CrI, 0.82-1.38]) and the probabilities of harm from hydroxychloroquine (96.9%; HR, 1.51 [95% CrI, 0.98-2.29]) and the combination of lopinavir-ritonavir and hydroxychloroquine (96.8%; HR, 1.61 [95% CrI, 0.97-2.67]) were high. The corticosteroid domain was stopped early prior to reaching a predefined statistical trigger; there was a 57.1% to 61.6% probability of improving 6-month survival across varying hydrocortisone dosing strategies.Conclusions and RelevanceAmong critically ill patients with COVID-19 randomized to receive 1 or more therapeutic interventions, treatment with an IL-6 receptor antagonist had a greater than 99.9% probability of improved 180-day mortality compared with patients randomized to the control, and treatment with an antiplatelet had a 95.0% probability of improved 180-day mortality compared with patients randomized to the control. Overall, when considered with previously reported short-term results, the findings indicate that initial in-hospital treatment effects were consistent for most therapies through 6 months.
- Published
- 2023
26. Polymeric microspheres for the sustained release of a protein-based drug carrier targeting the PDGFβ-receptor in the fibrotic kidney
- Author
-
Teekamp, N., Van Dijk, F., Broesder, A., Evers, M., Zuidema, J., Steendam, R., Post, E., Hillebrands, J. L., Frijlink, H. W., Poelstra, K., Beljaars, L., Olinga, P., and Hinrichs, W. L.J.
- Published
- 2017
- Full Text
- View/download PDF
27. sp-hybridized carbon atoms formed by low-energy collisions in carbon nanofoams produced by pulsed laser deposition
- Author
-
Lustosa, A.C.L.B., Evers, M., Franceschini, D.F., Litterst, F.J., and Xing, Yutao
- Published
- 2022
- Full Text
- View/download PDF
28. Optimising conditions for production of 6He, 8Li, 10Be and 12B radioactive ion beams with the SOLEROO separator
- Author
-
Horsley, A.J., Hinde, D.J., Dasgupta, M., Rafiei, R., Wakhle, A., Evers, M., Luong, D.H., and du Rietz, R.
- Published
- 2011
- Full Text
- View/download PDF
29. SOLEROO: A solenoidal exotic rare isotope separator at the Australian National University
- Author
-
Rafiei, R., Hinde, D.J., Dasgupta, M., Weisser, D.C., Muirhead, A.G., Harding, A.B., Cooper, A.K., Wallace, H.J., Lobanov, N.R., Wakhle, A., Brown, M.L., Lin, C.J., Horsley, A.J., du Rietz, R., Luong, D.H., and Evers, M.
- Published
- 2011
- Full Text
- View/download PDF
30. Polytrauma at the Emergency Department; can we relate arterial blood gas analysis to a shock classification?
- Author
-
Evers, M. J., Vaneker, M., and Biert, J.
- Published
- 2014
- Full Text
- View/download PDF
31. Quantum coherence and decoherence in low energy nuclear collisions: from superposition to irreversibility
- Author
-
Hinde, D.J., Dasgupta, M., Diaz-Torres, A., and Evers, M.
- Published
- 2010
- Full Text
- View/download PDF
32. Reaction dynamics of weakly bound nuclei at near-barrier energies
- Author
-
Dasgupta, M., Gasques, L.R., Luong, D.H., du Rietz, R., Rafiei, R., Hinde, D.J., Lin, C.J., Evers, M., and Diaz-Torres, A.
- Published
- 2010
- Full Text
- View/download PDF
33. Polarized phonons carry the missing angular momentum in femtosecond demagnetization
- Author
-
Tauchert, S. R., Volkov, M., Ehberger, D., Kazenwadel, D., Evers, M., Lange, H., Donges, A., Book, A., Kreuzpaintner, W., Nowak, U., and Baum, P.
- Subjects
Condensed Matter - Materials Science ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,Physics::Optics - Abstract
Magnetic phenomena are ubiquitous in our surroundings and indispensable for modern science and technology, but it is notoriously difficult to change the magnetic order of a material in a rapid way. However, if a thin nickel film is subjected to ultrashort laser pulses, it can lose its magnetic order almost completely within merely femtosecond times. This phenomenon, in the meantime also observed in many other materials, has connected magnetism with femtosecond optics in an efficient, ultrafast and complex way, offering opportunities for rapid information processing or ultrafast spintronics at frequencies approaching those of light. Consequently, the physics of ultrafast demagnetization is central to modern material research, but a crucial question has remained elusive: If a material loses its magnetization within only femtoseconds, where is the missing angular momentum in such short time? Here we use ultrafast electron diffraction to reveal in nickel an almost instantaneous, long-lasting, non-equilibrium population of anisotropic high-frequency phonons that appear as quickly as the magnetic order is lost. The anisotropy plane is perpendicular to the direction of the initial magnetization and the atomic oscillation amplitude is 2 pm. We explain these observations by means of circularly polarized phonons that quickly absorb the missing angular momentum of the spin system before the slower onset of a macroscopic sample rotation. The time that is needed for demagnetization is related to the time it takes to accelerate the atoms. These results provide an atomistic picture of ultrafast demagnetization under adherence to all conservation laws but also demonstrate the general importance of polarized phonons for non-equilibrium dynamics and provide innovative ways for controlling materials on atomic dimensions.
- Published
- 2021
34. The Role of Big Data and Advanced Analytics in Drug Discovery, Development, and Commercialization
- Author
-
Szlezák, N, Evers, M, Wang, J, and Pérez, L
- Published
- 2014
- Full Text
- View/download PDF
35. Cognitive performance in neurokinin 3 receptor knockout mice
- Author
-
Nordquist, R. E., Delenclos, M., Ballard, T. M., Savignac, H., Pauly-Evers, M., Ozmen, L., and Spooren, W.
- Published
- 2008
- Full Text
- View/download PDF
36. PSDEFOPAT – TOWARDS AUTOMATIC MODEL BASED PSI POST-PROCESSING.
- Author
-
Evers, M., Thiele, A., Hammer, H., and Hinz, S.
- Subjects
DEFORMATION of surfaces ,GLACIAL isostasy ,SOIL consolidation ,SURFACE of the earth ,REMOTE sensing - Abstract
The deformation of the surface of the earth is triggered by numerous naturally occurring and artificial processes such as global isostatic adjustment, aseismic and coseismic movement, varying amounts of groundwater or gas stored underground, and soil consolidation due to urbanization. Monitoring these surface deformations is essential to understand the underlying processes and provide authorities and the public with hazard assessments. Remote sensing techniques, such as Persistent Scatterer Interferometry (PSI), have the capability of mapping these deformations. Besides a spatial analysis of the deformation patterns, PSI also provides information on their temporal evolution. Post-processing strategies to analyze the displacement time series have gained interest in recent years. This paper presents our PSI post-processing strategy, which incorporates different deformation models and automatically chooses the best-fitting one based on statistical tests. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
37. The relationship between strength, sprint power and aerobic power in adults with cerebral palsy: J6
- Author
-
DE GROOT, S, DALLMEIJER, A J, EVERS, M, VAN DER LUIJT, P, VAN DER WOUDE, L H, NIENHUIJS, K N, and JANSSEN, T W
- Published
- 2011
38. ANTISENSE-BASED EXON SKIPPING AS A THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY, STATUS AND PROSPECTS: MT 4-3
- Author
-
van Ommen, G.-J., Aartsma-Rus, A., Evers, M., van Roon, W., ʼtHoen, P.-B., Kemaladewi, D., Verbeek, S., Yllmaz-Elis, S., Dauwerse, H., Lesnik-Oberstein, S., den Dunnen, J. T., Goemans, N., Tulinus, M., Verschuuren, J., de Kimpe, S., Campion, G., and van Deutekom, J.
- Published
- 2011
39. UTILIZATION OF RNA-MODULATING THERAPEUTICS TO TARGET EXPANDED POLYGLUTAMINE REPEAT IN MUTANT HUNTINGTIN: D02
- Author
-
Evers, M, van Deutekom, J, den Dunnen, J, van Ommen, G-J, and van Roon-Mom, W
- Published
- 2009
- Full Text
- View/download PDF
40. 117番元素Ts合成のための48Ca+249Bk融合反応
- Author
-
Khuyagbaatar, J., Yakushev, A., Düllmann, Ch E., Ackermann, D., Andersson, L. L., Asai, M., Block, M., Boll, R. A., Brand, H., Cox, D. M., Dasgupta, M., Derkx, X., Di Nitto, A., Eberhardt, K., Even, J., Evers, M., Fahlander, C., Forsberg, U., Gates, J. M., Gharibyan, N., Golubev, P., Gregorich, K. E., Hamilton, J. H., Hartmann, W., Herzberg, R. D., Heßberger, F. P., Hinde, D. J., Hoffmann, J., Hollinger, R., Hübner, A., Jäger, E., Kindler, B., Kratz, J. V., Krier, J., Kurz, N., Laatiaoui, M., Lahiri, S., Lang, R., Lommel, B., Maiti, M., Miernik, K., Minami, S., Mistry, A., Mokry, C., Nitsche, H., Omtvedt, J. P., Pang, G. K., Papadakis, P., Renisch, D., Roberto, J., Rudolph, D., Runke, J., Rykaczewski, K. P., Sarmiento, L. G., Schädel, M., Schausten, B., Semchenkov, A., Shaughnessy, D. A., Steinegger, P., Steiner, J., Tereshatov, E. E., Thörle-Pospiech, P., Tinschert, K., Torres De Heidenreich, T., Trautmann, N., Türler, A., Uusitalo, J., Ward, D. E., Wegrzecki, M., Wiehl, N., Van Cleve, S. M., and Yakusheva, V.
- Subjects
gas-filled separator ,superheavy elements ,element 117 (Ts) ,alpha decay ,Subatomic Physics ,Nuclear Theory ,low and intermediate energy heavy-ion reactions ,ydinfysiikka ,Nuclear Experiment ,nuclear structure and decays - Abstract
We have performed an experiment to synthesize the element 117 (Ts) with the $^{48}$Ca+$^{249}$Bk fusion reaction. Four $\alpha$-decay chains attributed to the element 117 were observed. Two of them were long decay chains which can be assigned to the one originating from the $\alpha$ decay of $^{294}$Ts. The other two were short decay chains which are consistent with the one originating from the $\alpha$ decay of $^{293}$Ts. We have compared the present results with the literature data, and found that our present results mostly confirmed the literature data, leading to the firm confirmation of the synthesis of the element 117., $^{48}$Ca+$^{249}$B融合反応を用いて117番元素(Ts)合成実験を行い、117番元素に起因すると思われる4つの$\alpha$崩壊連鎖を観測した。うち2つは長い崩壊連鎖で、$^{294}$Tsの$\alpha$崩壊に起因するものと同定された。他の2つは短い崩壊連鎖で、$^{293}$Tsの$\alpha$崩壊に起因すると考えると矛盾しない。今回の結果と過去の文献値を比較したところ、今回の我々の結果は過去の文献値をほぼ再現し、117番元素合成の事実を強く再確認する結果となった。
- Published
- 2019
41. Changed environmental conditions weaken sexual selection in sticklebacks
- Author
-
CANDOLIN, U., SALESTO, T., and EVERS, M.
- Published
- 2007
42. Heat shock protein 90 antibodies in autism
- Author
-
Evers, M, Cunningham-Rundles, C, and Hollander, E
- Published
- 2002
- Full Text
- View/download PDF
43. CONCEPT TO ANALYZE THE DISPLACEMENT TIME SERIES OF INDIVIDUAL PERSISTENT SCATTERERS.
- Author
-
Evers, M., Thiele, A., Hammer, H., Cadario, E., Schulz, K., and Hinz, S.
- Subjects
TIME series analysis ,LANDSLIDES ,SYNTHETIC aperture radar ,SINE function ,SURFACE of the earth ,LINEAR velocity - Abstract
Persistent Scatterer Interferometry (PSInSAR) exploits a time series of Synthetic Aperture Radar (SAR) images to estimate the mean velocity with which the surface of the earth is deforming. However, most PSInSAR algorithms estimate the mean velocities using a linear regression model. Since some deformation phenomena can exhibit a more complex behavior over time, using a linear regression model leads to potentially wrong estimations for the mean velocity. For example, the velocity of a landslide moving down a steep slope can change depending on the water content of the material of the landslide, or an inactive landslide can reactivate due to an earthquake. Both scenarios would not result in a time series with a constant linear slope but in a piecewise linear time series.This paper presents a Matlab-based tool to analyze an individual Persistent Scatterer (PS) time series. The Persistent Scatterer Deformation Pattern Analysis Tool (PSDefoPAT) aims to build a mathematical model that sufficiently describes the time series trend and seasonal and noise components. The trend component is estimated using polynomial regression and piecewise linear models, while a sine function approximates the seasonal component. The goal is to identify the best fitting model for the displacement time series of a PS. PSDefoPAT is introduced by examine the time series of three different PS located in the region surrounding Patras, Greece. Based on the derived models, we discuss the nature of their deformation patterns. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
44. Impairment of L-type Ca2+ channel-dependent forms of hippocampal synaptic plasticity in mice deficient in the extracellular matrix glycoprotein tenascin-C
- Author
-
Evers, M. R., Salmen, B., Bukalo, O., Rollenhagen, A., Boösl, M. R., Morellini, F., Bartsch, U., Dityatev, A., and Schachner, M.
- Published
- 2003
45. Impact of environmental housing conditions on the emotional responses of mice deficient for nociceptin/orphanin FQ peptide precursor gene
- Author
-
Ouagazzal, A. -M., Moreau, J. -L., Pauly-Evers, M., and Jenck, F.
- Published
- 2003
- Full Text
- View/download PDF
46. OrphaninFQ: role in behavioral fear responses and vulnerability to stress?
- Author
-
Jenck, F, Ouagazzal, A M, Pauly-Evers, M, and Moreau, J-L
- Published
- 2000
- Full Text
- View/download PDF
47. ARYLSULFATASE A DEFICIENT MICE A MODEL FOR SULFATIDE LIPIDOSIS
- Author
-
Hess, B., Saftig, P., Hartmann, D., Coenen, R., Lüllmann-Rauch, R., Goebel, H. H., Evers, M., Figura, K. v., D'Hooge, R., Nagels, G., De Deyn, P., Peters, C., and Gieselmann, V.
- Published
- 1997
48. OA07.03 A Phase II Study of Frontline Rucaparib + Nivolumab in Platinum Sensitive ES SCLC: Interim Analysis
- Author
-
Chauhan, A., Kolesar, J., Yan, D., Maskey, A., Gaurav, K., Mcgarry, R., Miller, J., Khurana, A., O'Neal, R., Veedu, J., Kloecker, G., Park, C., Flora, D., Mullett, T., Evers, M., Anthony, L., Zinner, R., and Arnold, S.
- Published
- 2021
- Full Text
- View/download PDF
49. Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function
- Author
-
Higgins, G.A, Grottick, A.J, Ballard, T.M, Richards, J.G, Messer, J, Takeshima, H, Pauly-Evers, M, Jenck, F, Adam, G, and Wichmann, J
- Published
- 2001
- Full Text
- View/download PDF
50. Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants
- Author
-
Dueck, A., Evers, M., Henz, S. R., Unger, K., Eichner, N., Merkl, Rainer, Berezikov, E., Engelmann, Julia C., Weigel, D., Wenzl, S., Meister, Gunter, Stem Cell Aging Leukemia and Lymphoma (SALL), and Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)
- Subjects
Evolution ,DATABASE ,PREDICTION ,CHLAMYDOMONAS-REINHARDTII ,CLASSIFICATION ,Evolution, Molecular ,HUMAN ARGONAUTE PROTEINS ,MIRNAS ,ARABIDOPSIS ,SIRNAS ,MICRORNA ,ELEMENTS ,microRNAs ,Gene silencing ,Transposons ,Small RNAs ,Argonaute ,Volvox carteri ,Gene Expression Regulation, Plant ,Genetics ,570 Biowissenschaften, Biologie ,Nucleotide Motifs ,Binding Sites ,Base Sequence ,Gene Expression Profiling ,Computational Biology ,Reproducibility of Results ,Molecular Sequence Annotation ,Volvox ,Argonaute Proteins ,DNA Transposable Elements ,RNA, Small Untranslated ,ddc:570 ,Transcriptome ,Research Article ,Protein Binding ,Biotechnology - Abstract
Background Volvox carteri (V. carteri) is a multicellular green alga used as model system for the evolution of multicellularity. So far, the contribution of small RNA pathways to these phenomena is not understood. Thus, we have sequenced V. carteri Argonaute 3 (VcAGO3)-associated small RNAs from different developmental stages. Results Using this functional approach, we define the Volvox microRNA (miRNA) repertoire and show that miRNAs are not conserved in the closely related unicellular alga Chlamydomonas reinhardtii. Furthermore, we find that miRNAs are differentially expressed during different life stages of V. carteri. In addition to miRNAs, transposon-associated small RNAs or phased siRNA loci, which are common in higher land plants, are highly abundant in Volvox as well. Transposons not only give rise to miRNAs and other small RNAs, they are also targets of small RNAs. Conclusion Our analyses reveal a surprisingly complex small RNA network in Volvox as elaborate as in higher land plants. At least the identified VcAGO3-associated miRNAs are not conserved in C. reinhardtii suggesting fast evolution of small RNA systems. Thus, distinct small RNAs may contribute to multicellularity and also division of labor in reproductive and somatic cells. Electronic supplementary material The online version of this article (doi:10.1186/s12864-016-3202-4) contains supplementary material, which is available to authorized users.
- Published
- 2016
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.