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This work was undertaken to evaluate the biological activity of the aqueous extract of the dry seeds of Aframomum daniellii seeds on the copulatory performance of rats with testicular deficiency.Hypogonadal adult male rats (30) were divided into 6 groups: group I received distilled water (10 ml/kg), group II received sildenafil citrate (5 mg/kg), group III received intramuscular injections of testosterone enanthate (3. 6 mg/kg), group IV, V, and VI received the aqueous extract of A. daniellii at the respective doses of 100, 200, and 400 mg/kg/po/day for 14 days. The copulatory performance of the animals were assessed on days 1, 7 and 14 through the following copulation parameters: Mount, intromission, and ejaculation latency (ML, IL, and EL) and frequency (MF, IF and EF), average interval of copulation (AIC) and post-ejaculatory interval (PEI)). We noticed a significant decrease of ML (p < 0.05), IL (p < 0.01), EL (p < 0.001) and the increase of MF, IF and EF (p < 0.01) particularly at doses of 100 and 400 mg/kg when compared to group I and II. In addition, we noticed a significant increase of AIC from day 7 (p < 0.05) to day 14 (p < 0.001) at the same two doses while the PEI significantly decreased from the 1st (p < 0.01) to the 14th day (p < 0.001) when compared to group I and II. These findings demonstrated that A. daniellii aqueous extract of seeds enhanced pro-sexual potential and pro-sexual desire in male rats with testicular deficiency.

While the burden of metabolic syndrome (MetS) is still increasing in sub-Saharan Africa, there is a lack of data among young Cameroonian population. The aim of this study was to evaluate the prevalence of MetS and its components among secondary school students in Douala. This was a cross-sectional prospective study carried out on 803 students recruited from February to May 2021 in public and private secondary schools in Douala city, Cameroon. MetS was assessed according to the IDF/AHA/NHLBI 2009 consensus definition. The data collection consisted of a questionnaire on sociodemographic characteristics, measurement of anthropometric parameters (height, weight, body mass index (BMI), waist circumference) and overnight fasting blood sample. Blood pressure (BP), fasting blood glucose, HDL cholesterol and triglycerides were measured using standard methods. The mean age was 18±3 years, 73.3% female. The prevalence of MetS was 27.4%, common among participants aged ≥16 years, and higher in females compare to males (33.7% vs. 11.1%, P<0.0001). The prevalence of MetS components i.e abdominal obesity, high BP, fasting hyperglycemia, low-level HDL cholesterol and hypertriglyceridemia were 14.1, 18.1, 42.8, 51.4 and 38.6% respectively. All MetS components were significantly higher in females compared to males except for high BP which was similar among the genders. In our study population, the prevalence of MetS is high and this calls for improved monitoring to limit the evolution of associated cardiometabolic complications among young Cameroonians. [ABSTRACT FROM AUTHOR]