532 results on '"Ernst, Beat"'
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2. Analogues of the pan-selectin antagonist rivipansel (GMI-1070)
3. Does size matter? – Comparing pyranoses with septanoses as ligands of the bacterial lectin FimH
4. Strengthening an Intramolecular Non‐Classical Hydrogen Bond to Get in Shape for Binding.
5. Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics.
6. Does targeting Arg98 of FimH lead to high affinity antagonists?
7. Antiadhesive natural products against uropathogenic E. coli: What can we learn from cranberry extract?
8. Combating DC‐SIGN‐mediated SARS‐CoV‐2 dissemination by glycan‐mimicking polymers.
9. Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy
10. 2-C-Branched mannosides as a novel family of FimH antagonists—Synthesis and biological evaluation
11. Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation.
12. Quantitative profiling of prostaglandins as oxidative stress biomarkers in vitro and in vivo by negative ion online solid phase extraction – Liquid chromatography–tandem mass spectrometry
13. Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8
14. Prodruggability of carbohydrates--oral FimH antagonists
15. pKa determination by 1H NMR spectroscopy – An old methodology revisited
16. Chemical Development of Intracellular Protein Heterodimerizers
17. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewis x Mimetics.
18. Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists
19. E-selectin ligand complexes adopt an extended high-affinity conformation
20. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice
21. Kinetic and thermodynamic properties of MAG antagonists
22. Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein
23. Probing the carbohydrate recognition domain of E-selectin: The importance of the acid orientation in sLe x mimetics
24. The intrinsic conformation of a Lewis antigen: The Lewis × trisaccharide
25. Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)
26. Epitope Structure of the Carbohydrate Recognition Domain of Asialoglycoprotein Receptor to a Monoclonal Antibody Revealed by High-Resolution Proteolytic Excision Mass Spectrometry
27. New sialyl Lewis x mimic containing an α-substituted β 3-amino acid spacer
28. Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?
29. Trivalent, Gal/Gal NAc-containing ligands designed for the asialoglycoprotein receptor
30. Implications of the E-selectin S128R mutation for drug discovery
31. Biochemical characterization of Helicobacter pylori α-1,4 fucosyltransferase: metal ion requirement, donor substrate specificity and organic solvent stability
32. From carbohydrate leads to glycomimetic drugs
33. Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth.
34. Extraction and analysis of intact glucosinolates—A validated pressurized liquid extraction/liquid chromatography–mass spectrometry protocol for Isatis tinctoria, and qualitative analysis of other cruciferous plants
35. Mimetics of the tri- and tetrasaccharide epitope of GQ1bα as myelin-associated glycoprotein (MAG) ligands
36. Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)
37. The price of flexibility – a case study on septanoses as pyranose mimetics† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04289b
38. Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics
39. Cutaneous iontophoretic delivery of CGP69669A, a sialyl Lewisx mimetic, in vitro
40. Substrate and Donor Specificity of Glycosyl Transferases
41. EUROCarbDB: An open-access platform for glycoinformatics
42. Substrate specificity of fucosyl transferase III: an efficient synthesis of sialyl [Lewis.sup.x]-, sialyl [Lewis.sup.a]- derivatives and mimetics thereof
43. Isolation and characterization of two new Lys49 PLA2s with heparin neutralizing properties from Bothrops moojeni snake venom
44. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties.
45. A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN.
46. Application of homonuclear 3D NMR experiments and 1D analogs to study the conformation of sialyl Lewisx bound to E-selectin
47. Molecular cloning and functional expression of a novel Helicobacter pylori α-1,4 fucosyltransferase
48. Synthesis of aryl sialosides using Mitsunobu conditions
49. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy Against the DC-SIGN-mediated Dissemination of SARS-CoV-2.
50. Poly‐l‐lysine Glycoconjugates Inhibit DC‐SIGN‐mediated Attachment of Pandemic Viruses.
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