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The use of hematological counts for the prevention, diagnosis and follow-up of hematological diseases has increased. Indeed, the correct operation of a clinical laboratory is essential to producing comparable results. However, there is a paucity of validation and reproducibility studies among the different existing methods for clinical analysis. Therefore, our aim was to assess the commutability of the results provided by analyzers with different measuring systems. Sixty venous blood samples were obtained from patients, without discriminating for age or sex. Then, an automated hematological analysis was performed using the Cell-Dyn Ruby and HumaCount 5L instruments. The variables measured were: RBC, Hb, HCT, MCV, MCH and MCHC. The data were compared by a one-way ANOVA and Pearson’s correlation coefficient. Statistical significance was fixed at p < 0.05. There were no statistically significant differences for RBC, HCT, MCH or MCHC. In addition, with the exception of MCHC, all the analytes showed a good correlation coefficient between the two instruments. There is a variety of automated systems for the clinical laboratory and it is essential for the clinician to know the different methodologies used in hematological analyzers as well as their sensitivity and specificity. Therefore, our results are useful for demonstrating the importance of practical knowledge of the analyzers mentioned. [ABSTRACT FROM AUTHOR]

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El aumento de la morbilidad y mortalidad de pacientes con VSR en las épocas de invierno es un fenómeno bien conocido, donde las causas en niños menores de cinco años, están asociadas con los cambios de temperatura y humedad (extremos máximos y mí­nimos), constituyendo un factor significativo en las infecciones respiratorias, que se establecen como una de las patologí­as más frecuentes en niños menores de cinco años en todo el mundo. En paí­ses en desarrollo como Colombia, se presenta una incidencia del 95 % de los casos reportados, donde sus tasas de mortalidad son altas, resultando que el 72.4 % se da en menores de un año. El VSR es altamente contagioso; puede llegar a sobrevivir hasta siete horas en el hospedador; el 90 % de los niños se infecta con VSR durante los primeros cinco años de vida, y hasta un 40 % muestra compromiso de las ví­as aéreas inferiores. Para la realización de esta revisión se utilizó bases de datos electrónicas nacionales e internacionales, reflejando los conceptos en evolución sobre la variabilidad estacional y la afectación del VSR en niños menores de cinco años. Â Artí­culo de Revisión

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