8 results on '"Edward S, Ahn"'
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2. Fetal Surgery in the Era of SARS-CoV-2 Pandemic: A Single-Institution Review
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Kavita Narang, MD, Amro Elrefaei, MBBCh, Michelle A. Wyatt, MD, Lindsay L. Warner, MD, Ayssa Teles Abrao Trad, MD, Leal G. Segura, MD, Ellen Bendel-Stenzel, MD, Edward S. Ahn, MD, Katherine W. Arendt, MD, M. Yasir Qureshi, MBBS, and Rodrigo Ruano, MD, PhD
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Medicine (General) ,R5-920 - Abstract
Objective: To cope with the changing health care services in the era of SARS-CoV-2 pandemic. We share the institutional framework for the management of anomalous fetuses requiring fetal intervention at Mayo Clinic, Rochester, Minnesota. To assess the success of our program during this time, we compare intraoperative outcomes of fetal interventions performed during the pandemic with the previous year. Patients: We implemented our testing protocol on patients undergoing fetal intervention at our institution between March 1, and May 15, 2020, and we compared it with same period a year before. A total of 17 pregnant patients with anomalous fetuses who met criteria for fetal intervention were included: 8 from 2019 and 9 from 2020. Methods: Our testing protocol was designed based on our institutional perinatal guidelines, surgical requirements from the infection prevention and control (IPAC) committee, and input from our fetal surgery team, with focus on urgency of procedure and maternal SARS-CoV-2 screening status. We compared the indications, types of procedures, maternal age, gestational age at procedure, type of anesthesia used, and duration of procedure for cases performed at our institution between March 1, 2020, and May 15, 2020, and for the same period in 2019. Results: There were no statistically significant differences among the number of cases, indications, types of procedures, maternal age, gestational age, types of anesthesia, and duration of procedures (P values were all >.05) between the pre–SARS-CoV-2 pandemic in 2019 and the SARS-CoV-2 pandemic in 2020. Conclusions: Adoption of new institutional protocols during SARS-CoV-2 pandemic, with appropriate screening and case selection, allows provision of necessary fetal intervention with maximal benefit to mother, fetus, and health care provider.
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- 2020
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3. Fetal Surgery in the Era of SARS-CoV-2 Pandemic: A Single-Institution Review
- Author
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Edward S. Ahn, Kavita Narang, M. Yasir Qureshi, Michelle A. Wyatt, Ayssa Teles Abrao Trad, Amro Elrefaei, Katherine W. Arendt, Ellen M. Bendel-Stenzel, Leal G. Segura, Lindsay L. Warner, and Rodrigo Ruano
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medicine.medical_specialty ,AGP, Aerosol generating procedures ,MAC, Monitored anesthesia care ,medicine.medical_treatment ,FETO, Fetoscopic endoluminal tracheal occlusion ,ACOG, American College of Obstetrics and Gynecology ,Psychological intervention ,030204 cardiovascular system & hematology ,Twin-to-twin transfusion syndrome ,Article ,WHO, World health organization ,AFPS, American foundation for patient safety ,SMFM, Society for Maternal and Fetal Medicine ,03 medical and health sciences ,qRT-PCR, Quantitative real time polymerase chain reaction ,0302 clinical medicine ,Health care ,Fetal intervention ,Pandemic ,medicine ,030212 general & internal medicine ,fetal anomalies ,NAFTNet, North American Fetal Therapy Network ,GA, General anesthesia ,Pregnancy ,lcsh:R5-920 ,business.industry ,Fetal surgery ,SARS-CoV-2 ,Gestational age ,COVID-19 ,COVID-19, Coronavirus 2019 ,IFMSS, International Fetal Medicine and Surgery society ,medicine.disease ,CDH, Congenital diaphragmatic hernia ,OR, Operating room ,TAPS, Twin anemia polycythemia sequence ,LUTO, lower urinary tract obstruction ,Emergency medicine ,pregnancy ,business ,TTTS, Twin to twin transfusion syndrome ,lcsh:Medicine (General) ,ASA, American Society of Anesthesiology - Abstract
Objective To cope with the changing health care services in the era of SARS-CoV-2 pandemic. We share the institutional framework for the management of anomalous fetuses requiring fetal intervention at Mayo Clinic, Rochester, Minnesota. To assess the success of our program during this time, we compare intraoperative outcomes of fetal interventions performed during the pandemic with the previous year. Patients We implemented our testing protocol on patients undergoing fetal intervention at our institution between March 1, and May 15, 2020, and we compared it with same period a year before. A total of 17 pregnant patients with anomalous fetuses who met criteria for fetal intervention were included: 8 from 2019 and 9 from 2020. Methods Our testing protocol was designed based on our institutional perinatal guidelines, surgical requirements from the infection prevention and control (IPAC) committee, and input from our fetal surgery team, with focus on urgency of procedure and maternal SARS-CoV-2 screening status. We compared the indications, types of procedures, maternal age, gestational age at procedure, type of anesthesia used, and duration of procedure for cases performed at our institution between March 1, 2020, and May 15, 2020, and for the same period in 2019. Results There were no statistically significant differences among the number of cases, indications, types of procedures, maternal age, gestational age, types of anesthesia, and duration of procedures (P values were all >.05) between the pre–SARS-CoV-2 pandemic in 2019 and the SARS-CoV-2 pandemic in 2020. Conclusions Adoption of new institutional protocols during SARS-CoV-2 pandemic, with appropriate screening and case selection, allows provision of necessary fetal intervention with maximal benefit to mother, fetus, and health care provider.
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- 2020
4. Acceleration and Plateau: Two patterns and outcomes of isolated severe fetal cerebral ventricular dilation
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Karin J. Blakemore, Edward S. Ahn, Ahmet Baschat, Kristin W. Barañano, Eric B. Jelin, Christina J. Ge, Angie C. Jelin, Irina Burd, and Rosa M. Polan
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endocrine system ,medicine.medical_specialty ,Acceleration ,macromolecular substances ,Ventriculoperitoneal Shunt ,Article ,Cerebral Ventricles ,03 medical and health sciences ,0302 clinical medicine ,Fetus ,Pregnancy ,Internal medicine ,Medicine ,Humans ,Cerebral ventricular ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,medicine.disease ,Dilatation ,Hydrocephalus ,In utero ,Pediatrics, Perinatology and Child Health ,Cerebral ventricle ,Cardiology ,Dilation (morphology) ,Female ,business ,030217 neurology & neurosurgery ,Ventriculomegaly - Abstract
OBJECTIVES: We sought to characterize patterns of in utero dilation in isolated severe fetal ventriculomegaly (ISVM) and investigate their value in predicting obstetrical and postnatal outcomes. METHODS: This is a retrospective cohort study. ISVM was defined as a sonographic cerebral ventricle atrial width ≥15 mm in the absence of additional cerebral or other anatomic anomalies. The aim of this study was to characterize two ISVM groups using a receiver operator curve to evaluate the rate of ventricular progression versus need for ventriculoperitoneal (VP) shunt postnatally. Outcomes were compared between the groups using Pearson’s chi-squared test, Student t-test, and descriptive statistics. RESULTS: Based on the ROC analysis, ventricular growth of ≥3 mm/week versus
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- 2019
5. Respiratory outcomes after initial hospital discharge in children with ventricular shunts and bronchopulmonary dysplasia
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Edward S. Ahn, Joseph M. Collaco, and Sharon A. McGrath-Morrow
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Pulmonary and Respiratory Medicine ,Male ,medicine.medical_specialty ,Pediatrics ,Gestational Age ,Article ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Acute care ,Surveys and Questionnaires ,mental disorders ,medicine ,Humans ,Respiratory system ,Bronchopulmonary Dysplasia ,business.industry ,Infant, Newborn ,Gestational age ,Infant ,medicine.disease ,Cerebrospinal Fluid Shunts ,Patient Discharge ,Oxygen ,Intraventricular hemorrhage ,Bronchopulmonary dysplasia ,Caregivers ,Pediatrics, Perinatology and Child Health ,Gestation ,Population study ,Female ,business ,030217 neurology & neurosurgery ,Shunt (electrical) ,Infant, Premature - Abstract
Introduction Children born premature who require ventricular shunt placement for post hemorrhagic hydrocephalus are at increased risk for neurodevelopmental delay. We hypothesized that preterm infants with bronchopulmonary dysplasia (BPD) who require ventricular shunt (VS) placement are at additive risk for long-term respiratory morbidities due to their higher likelihood of neurodevelopmental delay. We also hypothesized that children with BPD and ventricular shunts would require frequent shunt revisions during early childhood following initial shunt placement. Methods All subjects were recruited from the Johns Hopkins Bronchopulmonary Dysplasia Clinic between January 2008 and November 2016. A review of demographic and clinical information was undertaken and a respiratory outcomes questionnaire was completed by the primary caregiver. Results Fifty-five (8.9%) of 623 subjects in the study population had ventricular shunts, with a mean 4.6 ± 2.3 years of follow-up data (range: 0.5-10.1). Subjects with VS were more likely to be born at earlier gestational ages and be discharged on supplemental oxygen compared to BPD subjects alone. Outpatient respiratory symptoms and acute care usage were similar between the two groups. BPD subjects with VS were more likely to have had gastric tubes placed. A total of 270 neurosurgical procedures were performed in subjects with VS with a mean of 4.9 ± 5.4 procedures/subject. Conclusion Children with ventricular shunts and BPD had similar outpatient respiratory outcomes compared to children with BPD alone; however respiratory morbidities may have been mitigated by the greater use of gastric tubes in the VS + BPD group. Multiple neurosurgical procedures were common in children with ventricular shunts.
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- 2017
6. Indications for Computer-Aided Design and Manufacturing in Congenital Craniofacial Reconstruction
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Edward S. Ahn, Amir H. Dorafshar, Miguel Medina, Mark Fisher, and Branko Bojovic
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medicine.medical_specialty ,Retrospective review ,Preoperative planning ,business.industry ,medicine.medical_treatment ,CAD ,030206 dentistry ,computer.software_genre ,Cranioplasty ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,medicine ,Distraction osteogenesis ,Computer Aided Design ,Medical physics ,Oral Surgery ,Craniofacial ,business ,computer - Abstract
The complex three-dimensional relationships in congenital craniofacial reconstruction uniquely lend themselves to the ability to accurately plan and model the result provided by computer-aided design and manufacturing (CAD/CAM). The goal of this study was to illustrate indications where CAD/CAM would be helpful in the treatment of congenital craniofacial anomalies reconstruction and to discuss the application of this technology and its outcomes. A retrospective review was performed of all congenital craniofacial cases performed by the senior author between 2010 and 2014. Cases where CAD/CAM was used were identified, and illustrative cases to demonstrate the benefits of CAD/CAM were selected. Preoperative appearance, computerized plan, intraoperative course, and final outcome were analyzed. Preoperative planning enabled efficient execution of the operative plan with predictable results. Risk factors which made these patients good candidates for CAD/CAM were identified and compiled. Several indications, including multisuture and revisional craniosynostosis, facial bipartition, four-wall box osteotomy, reduction cranioplasty, and distraction osteogenesis could benefit most from this technology. We illustrate the use of CAD/CAM for these applications and describe the decision-making process both before and during surgery. We explore why we believe that CAD/CAM is indicated in these scenarios as well as the disadvantages and risks.
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- 2016
7. Shunt revision requirements after posthemorrhagic hydrocephalus of prematurity: insight into the time course of shunt dependency
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Edward S. Ahn, Eric M. Jackson, George I. Jallo, and Joanna Wang
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Male ,medicine.medical_specialty ,Time Factors ,Tomography Scanners, X-Ray Computed ,Neurology ,Infant, Premature, Diseases ,Ventriculoperitoneal Shunt ,Statistics, Nonparametric ,Cerebral Ventricles ,Cellular and Molecular Neuroscience ,Developmental Neuroscience ,Posthemorrhagic hydrocephalus ,Outcome Assessment, Health Care ,Humans ,Medicine ,Cyst ,Cerebral Hemorrhage ,Retrospective Studies ,business.industry ,Infant ,Retrospective cohort study ,General Medicine ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Hydrocephalus ,Shunt (medical) ,Catheter ,Intraventricular hemorrhage ,Aqueductal stenosis ,Pediatrics, Perinatology and Child Health ,Oral Presentation ,Female ,Neurology (clinical) ,Neurosurgery ,business ,Infant, Premature ,Shunt (electrical) ,Follow-Up Studies - Abstract
Intraventricular hemorrhage (IVH) is a common affliction of preterm infants and often results in posthemorrhagic hydrocephalus (PHH). These patients typically eventually require permanent CSF diversion and are presumed to be indefinitely shunt-dependent. To date, however, there has been no study of long-term shunt revision requirements in patients with PHH. We analyzed retrospectively collected data for 89 preterm patients diagnosed with grades III and IV IVH and PHH at our institution from 1998 to 2011. Sixty-nine out of 89 patients (77.5 %) underwent ventriculoperitoneal (VP) shunt placement, and 33 (47.8 %) required at least one shunt revision and 18 (26.1 %) required multiple revisions. The mean ± standard deviation follow-up time for shunted patients was 5.0 ± 3.3 years. The majority of early failures were due to proximal catheter malfunction, while later failures were mostly due to distal catheter problems. There was a significant difference in the number of patients requiring revisions in the first 3 years following initial VP shunt insertion compared after 3 years, with 28 revisions versus 10 (p
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- 2015
8. Impact of tethered cord release on symptoms of Chiari II malformation in children born with a myelomeningocele
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Chetan Bettegowda, Anubhav G. Amin, Mahmood El-Gassim, Edward S. Ahn, Vivek A. Mehta, and George I. Jallo
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Male ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Meningomyelocele ,Adolescent ,Chiari malformation ,Clinical Neurology ,medicine ,Humans ,In patient ,Neural Tube Defects ,Pediatrics, Perinatology, and Child Health ,Tethered Cord ,Child ,Retrospective Studies ,Outcome ,Pediatric ,Original Paper ,business.industry ,General Medicine ,medicine.disease ,Spinal cord ,Decompression, Surgical ,nervous system diseases ,Surgery ,Arnold-Chiari Malformation ,Tethered spinal cord ,medicine.anatomical_structure ,Treatment Outcome ,Child, Preschool ,embryonic structures ,Pediatrics, Perinatology and Child Health ,Female ,Neurology (clinical) ,Neurosurgery ,Myelomeningocele ,business - Abstract
Purpose The role of distal traction in the form of a tethered spinal cord in exacerbating anatomical findings or symptoms of Chiari II malformation (CIIM) has been debated for decades. Despite the association of Chiari II malformation with myelomeningocele, the impact of tethered cord release on CIIM symptoms in patients has not been explored. Methods A retrospective review of 59 patients born with a myelomeningocele was performed. A total of 92 untethering procedures were performed in which symptoms of CIIM were present in 29 cases. In 57 out of 92 cases, the patients did not have symptoms of CIIM prior to untethering. Six cases were excluded because cervicomedullary decompression was performed prior to untethering. The response of CIIM symptoms, syrinx size, and cerebellar tonsil position were examined before and after spinal cord untethering. Results Forty-four characteristic signs and symptoms of CIIM were present prior to 29 untetherings. Thirty-three of 44 (75%) symptoms improved following spinal cord untethering, though no symptom resolved completely. Syrinx size and cerebellar tonsil position were unchanged following untethering. Conclusion The authors conclude that mild to moderate symptoms of CIIM may respond positively to spinal cord untethering, potentially by normalization cerebrospinal fluid flow dynamics. Symptom improvement occurs despite the lack of radiographic evidence of CIIM resolution.
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