21 results on '"Durán JC"'
Search Results
2. Evaluation of risperidone in the treatment of behavioral and psychological symptoms and sleep disturbances associated with dementia.
- Author
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Durán JC, Greenspan A, Diago JI, Gallego R, Martinez G, Durán, J C, Greenspan, A, Diago, J I, Gallego, R, and Martinez, G
- Abstract
Background: Dementia is associated with progressive cognitive impairment and behavioral and psychological symptoms. Sleep-wake cycle disturbances are common in patients with dementia. This study evaluated the efficacy and safety of risperidone in the treatment of the behavioral and psychological symptoms of dementia (BPSD) and associated sleep-wake cycle disturbances.Methods: In this open-label, 12-week, observational, prospective study, the effects of risperidone were assessed using the Neuropsychiatric Inventory (NPI) total and subscale scores. Sleep-wake cycle disturbances were rated by patients/caregivers using a newly developed sleep behavior questionnaire that included assessment of sleep duration, quality, awakenings, and effects on daily activities. Tolerability assessments included the Udvalg for Kliniske Undersogelser (UKU) subscale for extrapyramidal symptoms (EPS) and the recording of adverse events.Results: A total of 338 patients entered the study, with 321 patients completing. Following 12 weeks of risperidone treatment (mean dose 1.49 mg/day at end-point), the mean NPI score was reduced to 10.6 from a baseline score of 28.7. Compared with baseline, patients/caregivers reported significant improvements following 12 weeks of risperidone in total sleep hours at night (5.5 vs. 7.1 hours), hours awake in bed at night (2.3 vs. 1.2 hours), insomnia (40.1% vs. 8.4%), and other sleep-related variables. Six patients reported a total of 10 adverse events, including somnolence (n = 3) and sialorrhea (n = 2). Scores on the UKU subscale of EPS improved significantly (mean 4.0 at baseline vs. 1.7 at week 12).Conclusions: Risperidone is effective and well tolerated in the treatment of BPSD and associated sleep disturbances. [ABSTRACT FROM AUTHOR]- Published
- 2005
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3. Digital and analog techniques for cemento-enamel junction reconstruction: A case study.
- Author
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Durán JC, Gómez V, Aguilera C, Pino R, Sáiz V, González N, Cataldo Y, Gauro M, Urzúa I, Solanes F, and Madariaga C
- Abstract
Background: Non-carious cervical lesions (NCCLs) refer to the loss of dental hard tissue in the cervical region due to physical and/or chemical factors, often associated with the disappearance of the cemento-enamel junction (CEJ), posing challenges in both diagnosis and treatment of gingival recessions (GR). This case study introduces two protocols for multidisciplinary CEJ reconstruction prior to the root coverage therapy (RCT)., Methods: Two patients with GR and NCCLs were treated using two CEJ reconstruction techniques: both, analogically and digitally guided. For each case, the position of the therapeutic CEJ was predetermined using a combination of the methods described by Zucchelli and Cairo. Then, an analog or digital diagnostic wax-up was performed accordingly. In the analogically guided technique, a transparent silicone guide matrix was used to transfer information from the dental wax-up. In contrast, the digitally guided technique employed a rigid, translucent resin prosthetic guide matrix that was designed and printed. Restorations were fabricated using direct composite resin and RCT was performed 1 week later in both techniques., Results: At 6 months, both cases demonstrated complete root coverage and effective healing of the soft tissues surrounding the restorations., Conclusions: Dimensional changes in materials and precise guide adjustment in the analog technique are operator-dependent and can affect the outcomes. Digital procedures, though effective, are costly and may limit their use. The usage of these two CEJ reconstruction techniques enhances communication within the multidisciplinary team and ensures optimal aesthetic outcomes and precise placement of the gingival margin., Key Points: There are no established clinical protocols described in the literature for reconstructing the cemento-enamel junction (CEJ) once the position of a therapeutic CEJ has been predetermined and prior root coverage therapy (RCT). Performing a diagnostic wax-up (analogically or digitally) to reconstruct the therapeutic CEJ is crucial and facilitates the creation of a prosthetic guide that accurately reproduces the defined CEJ position. The reconstruction of the CEJ may improve the prognosis of RCT., Plain Language Summary: This study looked at a dental issue called non-carious cervical lesions, which happens when the hard tissue near the gum line of a tooth wears away, making it harder to treat gum recession. Two different approaches were tested to rebuild the lost tissue in the gum area before performing a procedure to cover the exposed roots. One approach used traditional methods with physical guides to help place the new tissue, while the other used advanced digital techniques to create a precise guide using 3D printing. After 6 months, both methods successfully covered the exposed roots and helped the gums heal properly. However, the traditional method's results can vary depending on the dentist's skill, while the digital method, although more accurate, can be expensive. Using these methods can improve teamwork among dental specialists and lead to better-looking results by ensuring the gum line is placed exactly where it should be., (© 2024 American Academy of Periodontology.)
- Published
- 2024
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4. Multidisciplinary Treatment of Deep Non-Carious Cervical Lesion With a CAD/CAM Chairside Restoration in Combination With Periodontal Surgery: A 60-Month Follow-Up Technique Report.
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Durán JC, Alarcón C, De la Jara D, Pino R, and Lanis A
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- Computer-Aided Design, Female, Follow-Up Studies, Humans, Surgical Flaps, Esthetics, Dental, Gingival Recession
- Abstract
Introduction: Restoring function and esthetics are essential aspects of periodontology and restorative dentistry. Depending on their extension and the tissues involved, the treatment of non-carious cervical lesions (NCCLs) associated with gingival recessions may require a multidisciplinary approach, and different periodontal and restorative techniques have been described., Case Presentation: This case report presents an innovative approach to treat a deep NCCL combined with a gingival recession in a canine region of a female patient. A Computer Aided Design - Computer Aided Manufacturing (CAD/CAM) chairside ceramic restoration in combination with mucogingival surgery procedures is described. A comprehensive analysis of the selected approach and its clinical implications is presented based on a 60-month follow-up. Conclusions After 60-month follow-up, clinical condition maintained stable, and a successful esthetic outcome was accomplished. Complete root coverage was achieved and kept throughout the whole period of tracing., (© 2021 American Academy of Periodontology.)
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- 2021
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5. Priorities to reduce the burden of stroke in Latin American countries.
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Ouriques Martins SC, Sacks C, Hacke W, Brainin M, de Assis Figueiredo F, Marques Pontes-Neto O, Lavados Germain PM, Marinho MF, Hoppe Wiegering A, Vaca McGhie D, Cruz-Flores S, Ameriso SF, Camargo Villareal WM, Durán JC, Fogolin Passos JE, Gomes Nogueira R, Freitas de Carvalho JJ, Sampaio Silva G, Cabral Moro CH, Oliveira-Filho J, Gagliardi R, Gomes de Sousa ED, Fagundes Soares F, de Pinho Campos K, Piza Teixeira PF, Gonçalves IP, Santos Carquin IR, Muñoz Collazos M, Pérez Romero GE, Maldonado Figueredo JI, Barboza MA, Celis López MÁ, Góngora-Rivera F, Cantú-Brito C, Novarro-Escudero N, Velázquez Blanco MÁ, Arbo Oze de Morvil CA, Olmedo Bareiro AB, Meza Rojas G, Flores A, Hancco-Saavedra JA, Pérez Jimenez V, Abanto Argomedo C, Rodriguez Kadota L, Crosa R, Mora Cuervo DL, de Souza AC, Carbonera LA, Álvarez Guzmán TF, Maldonado N, Cabral NL, Anderson C, Lindsay P, Hennis A, and Feigin VL
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- Humans, Incidence, Latin America epidemiology, Prevalence, Stroke mortality, Cost of Illness, Health Policy, Stroke epidemiology
- Abstract
The large and increasing burden of stroke in Latin American countries, and the need to meet the UN and WHO requirements for reducing the burden from non-communicable disorders (including stroke), brought together stroke experts and representatives of the Ministries of Health of 13 Latin American countries for the 1st Latin American Stroke Ministerial meeting in Gramado, Brazil, to discuss the problem and identify ways of cooperating to reduce the burden of stroke in the region. Discussions were focused on the regional and country-specific activities associated with stroke prevention and treatment, including public stroke awareness, prevention strategies, delivery and organisation of care, clinical practice gaps, and unmet needs. The meeting culminated with the adoption of the special Gramado Declaration, signed by all Ministerial officials who attended the meeting. With agreed priorities for stroke prevention, treatment, and research, an opportunity now exists to translate this Declaration into an action plan to reduce the burden of stroke., (Copyright © 2019 Elsevier Ltd. All rights reserved.)
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- 2019
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6. Giant periurethral condyloma acuminata in a 2-year-old girl: Successful treatment with carbon dioxide laser.
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Calderón-Castrat X, Blanco S, Santos-Durán JC, and Roncero-Riesco M
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- Child, Preschool, Female, Humans, Remission Induction, Condylomata Acuminata surgery, Laser Therapy, Lasers, Gas therapeutic use, Urethral Diseases surgery
- Published
- 2017
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7. Multiple primary cutaneous plasmacytoma a decade after a nasal solitary extramedullary plasmacytoma: a puzzling case.
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González-Calle V, Jorge-Finnigan C, Santos-Durán JC, López-Cadenas F, Ocio EM, García-Sanz R, Santos-Briz Á, Fernández-López E, San Miguel J, Mateos MV, and Román-Curto C
- Abstract
Primary cutaneous plasmacytoma should be in the differential diagnosis in case of solitary or multiple erythematous-violaceous nodules or papules. The diagnosis relies on clinical, histological, and immunochemical findings, without underlying evidence of multiple myeloma. Treatment should be individualized, and agents such as bortezomib or lenalidomide have shown to be effective.
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- 2016
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8. New diagnostic criteria for neurocysticercosis: Reliability and validity.
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Carpio A, Fleury A, Romo ML, Abraham R, Fandiño J, Durán JC, Cárdenas G, Moncayo J, Leite Rodrigues C, San-Juan D, Serrano-Dueñas M, Takayanagui O, and Sander JW
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- Adult, Female, Humans, Male, Middle Aged, Reproducibility of Results, Retrospective Studies, Sensitivity and Specificity, Consensus, Neurocysticercosis diagnosis, Practice Guidelines as Topic standards
- Abstract
Objective: The diagnosis of neurocysticercosis (NCC) remains problematic because of the heterogeneity of its clinical, immunological, and imaging characteristics. Our aim was to develop and assess a new set of diagnostic criteria for NCC, which might allow for the accurate detection of, and differentiation between, parenchymal and extraparenchymal disease., Methods: A group of Latin American NCC experts developed by consensus a new set of diagnostic criteria for NCC. A multicenter, retrospective study was then conducted to validate it. The reference standard for diagnosis of active NCC was the disappearance or reduction of cysts after anthelmintic treatment. In total, three pairs of independent neurologists blinded to the diagnosis evaluated 93 cases (with NCC) and 93 controls (without NCC) using the new diagnostic criteria. Mixed-effects logistic regression models were used to estimate sensitivity and specificity., Results: Inter-rater reliability (kappa) of diagnosis among evaluators was 0.60. For diagnosis of NCC versus no NCC, the new criteria had a sensitivity of 93.2% and specificity of 81.4%. For parenchymal NCC, the new criteria had a sensitivity of 89.8% and specificity of 80.7% and for extraparenchymal NCC, the new criteria had a sensitivity of 65.9% and specificity of 94.9%., Interpretation: These criteria have acceptable reliability and validity and could be a new tool for clinicians and researchers. An advantage of the new criteria is that they consider parasite location (ie, parenchymal or extraparenchymal), which is an important factor determining the clinical, immunological, and radiological presentation of the disease, and importantly, its treatment and prognosis. Ann Neurol 2016;80:434-442., (© 2016 The Authors. Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.)
- Published
- 2016
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9. Carbon Dioxide Laser: A Therapeutic Approach for Multiple Vulvar Epidermoid Cysts.
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Calderón-Castrat X, Santos-Durán JC, Román-Curto C, and Fernández-López E
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- Epidermal Cyst pathology, Female, Humans, Middle Aged, Treatment Outcome, Vulvar Diseases pathology, Epidermal Cyst surgery, Lasers, Gas therapeutic use, Vulvar Diseases surgery
- Published
- 2016
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10. Cutaneous annular lesions as the first sign of transformation of follicular lymphoma into diffuse large B-cell lymphoma.
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Palacios-Álvarez I, Román-Curto C, García-Sancho AM, Santos-Briz Á, Santos-Durán JC, and Fernández-López E
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- Aged, 80 and over, Female, Humans, Lymphoma, Follicular complications, Lymphoma, Large B-Cell, Diffuse complications, Mycosis Fungoides complications, Skin Neoplasms complications, Disease Progression, Lymphoma, Follicular diagnosis, Lymphoma, Large B-Cell, Diffuse diagnosis, Mycosis Fungoides diagnosis, Skin Neoplasms diagnosis
- Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma with diverse clinical, pathological and genetic features. An 80-year-old woman was diagnosed with a stage IV-X-A (Ann Arbor staging system) low grade systemic follicular lymphoma (FL). Four months after the diagnosis, she developed asymptomatic, indurated, annular erythematous plaques with centrifugal growth on the abdomen, arms and neck. The skin biopsy revealed a dermal infiltration compatible with diffuse large B-cell lymphoma. Light chain restriction by flow cytometry was demonstrated. The variable, diverse and joining genes of immunoglobulin G heavy chains were sequenced and cloned, and showed the same pattern for both the initial follicular lymphoma and the skin infiltration. Translocation t (14;18) was present in both samples. Based on these findings, a diagnosis of transformation of follicular lymphoma into diffuse large B cell lymphoma was made. Although other hematological disorders such as primary cutaneous diffuse large B cell lymphoma, mycosis fungoides and the cutaneous infiltration of chronic juvenile myeloid leukemia can present as annular lesions, we were unable to find any previous reports of these as a manifestation of cutaneous infiltration by systemic non-Hodgkin lymphoma.
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- 2015
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11. Biological and nonbiological complex drugs for multiple sclerosis in Latin America: regulations and risk management.
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Carrá A, Macías Islas MA, Tarulla A, Bichuetti DB, Finkelsztejn A, Fragoso YD, Árcega-Revilla R, Cárcamo Rodríguez C, Durán JC, Bonitto JG, León R, Oehninger Gatti C, Orozco G, and Vizcarra Escobar D
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- Expert Testimony, Humans, Latin America epidemiology, Multiple Sclerosis epidemiology, Biosimilar Pharmaceuticals therapeutic use, Drug and Narcotic Control, Immunologic Factors therapeutic use, Multiple Sclerosis drug therapy, Risk Management
- Abstract
Biological drugs and nonbiological complex drugs with expired patents are followed by biosimilars and follow-on drugs that are supposedly similar and comparable with the reference product in terms of quality, safety and efficacy. Unlike simple molecules that can be copied and reproduced, biosimilars and follow-on complex drugs are heterogeneous and need specific regulations from health and pharmacovigilance agencies. A panel of 14 Latin American experts on multiple sclerosis from nine different countries met to discuss the recommendations regarding biosimilars and follow-on complex drugs for treating multiple sclerosis. Specific measures relating to manufacturing, therapeutic equivalence assessment and pharmacovigilance reports need to be implemented before commercialization. Physical, chemical, biological and immunogenic characterizations of the new product need to be available before clinical trials start. The new product must maintain the same immunogenicity as the original. Automatic substitution of biological and complex drugs poses unacceptable risks to the patient.
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- 2015
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12. Chronic recurrent annular neutrophilic dermatosis associated with rheumatoid arthritis.
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Mir-Bonafé JM, Santos-Durán JC, Santos-Briz A, and Fernández-López E
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- Aged, Chronic Disease, Female, Humans, Neutrophils, Recurrence, Skin Diseases pathology, Arthritis, Rheumatoid complications, Skin Diseases etiology
- Published
- 2014
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13. Latin American consensus on guidelines for chronic migraine treatment.
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Giacomozzi AR, Vindas AP, Silva AA Jr, Bordini CA, Buonanotte CF, Roesler CA, Brito CM, Perez C, Carvalho Dde S, Macedo DD, Piovesan EJ, Sarmento EM, Melhado EM, Éckeli FD, Kowacs F, Sobrino F, Rabello GD, Rada G, Souza JA, Casanovas JR, Durán JC, Calia LC, Medina LR, Queiroz LP, Ciciarelli MC, Valença MM, Cusicanqui M, Jimenez MK, Goycochea MT, Peres MF, Sandoval MV, Vincent MB, Gomes MV, Diez M, Aranaga N, Barrientos N, Kowacs PA, and Filho PF
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- Chronic Disease, Comorbidity, Humans, Latin America, Migraine Disorders diagnosis, Risk Factors, Migraine Disorders therapy
- Abstract
Chronic migraine is a condition with significant prevalence all around the world and high socioeconomic impact, and its handling has been challenging neurologists. Developments for understanding its mechanisms and associated conditions, as well as that of new therapies, have been quick and important, a fact which has motivated the Latin American and Brazilian Headache Societies to prepare the present consensus. The treatment of chronic migraine should always be preceded by a careful diagnosis review; the detection of possible worsening factors and associated conditions; the stratification of seriousness/impossibility to treat; and monitoring establishment, with a pain diary. The present consensus deals with pharmacological and nonpharmacological forms of treatment to be used in chronic migraine.
- Published
- 2013
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14. Eczema herpeticum with herpetic folliculitis after bone marrow transplant under prophylactic acyclovir: are patients with underlying dermatologic disorders at higher risk?
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Mir-Bonafé JM, Román-Curto C, Santos-Briz A, Palacios-Álvarez I, Santos-Durán JC, and Fernández-López E
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- Adult, Anemia, Aplastic therapy, Cyclosporine therapeutic use, Dermatitis, Atopic complications, Female, Folliculitis prevention & control, Herpes Simplex prevention & control, Humans, Kaposi Varicelliform Eruption drug therapy, Risk Factors, Acyclovir therapeutic use, Antiviral Agents therapeutic use, Bone Marrow Transplantation, Folliculitis virology, Herpes Simplex virology, Herpesvirus 1, Human isolation & purification, Kaposi Varicelliform Eruption virology
- Abstract
We present an unreported coexistence: eczema herpeticum (EH) with histopathological findings of herpetic folliculitis (HF) after allogeneic bone marrow transplantation (BMT). A patient with atopic dermatitis (AD) underwent allogeneic BMT for idiopathic acquired aplastic anemia. She had been receiving cyclosporine (150 mg/12 h) and acyclovir (400 mg/12 h) for 6 months. A facial rash was observed, composed of monotonous erythematous, umbilicated papulo-vesicles and papulo-crusts <4 mm in size. The histopathological study showed herpetic cytopathic changes within the epidermis that extended into the hair follicle epithelium. Interestingly, microscopic HF has not previously been associated with post-transplant patients or EH. However, it is reasonable to hypothesize that the coexistence of these herpes simplex virus-related events may be underreported in the literature. Although further studies are necessary, we suggest that the prophylactic antiviral dose after BMT be enhanced in patients with underlying dermatologic diseases, especially in those with AD., (© 2013 John Wiley & Sons A/S.)
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- 2013
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15. Surgical lung biopsy for diffuse lung disease. Our experience in the last 15 years.
- Author
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Blanco M, Obeso GA, Durán JC, Rivo JE, García-Fontán E, Peña E, Rodríguez M, Albort J, and Cañizares MA
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- Biopsy methods, Female, Humans, Lung Diseases surgery, Male, Middle Aged, Retrospective Studies, Time Factors, Lung Diseases pathology
- Abstract
Introduction: Surgical lung biopsy is a technique that presents a morbi-mortality rate of considerable importance. We analyze our experience with surgical lung biopsies for the diagnosis of diffuse lung disease and the effect produced on the indications for surgical biopsy in these pathologies after the publication of the consensus of the ATS (American Thoracic Society) and ERS (European Respiratory Society) for Idiopathic Pulmonary Fibrosis (IPF)., Patients and Methods: We performed a retrospective review of 171 patients operated between January 1997 and December 2011. We divided the series into 2 groups: group 1 (operated between 1997 and 2002) and group 2 (operated between 2003 and 2011). Suspected preoperative diagnosis, respiratory status, pathological postoperative diagnoses, percentage of thoracotomies, mean postoperative stay and perioperative morbidity and mortality were analyzed., Results: Group 1 consisted of 99 patients and group two 72. The most frequent postoperative diagnoses were: usual interstitial pneumonia and extrinsic allergic alveolitis. There were ten (5.84%) deaths. Death was caused by progressive respiratory failure that was related to interstitial lung disease in 7 (70%) of 10 cases, alveolar haemorrhage in 2 (20%) and heart failure in 1 (10%)., Conclusions: Since the publication of the ATS and ERS consensus on the IPF, we have observed a noticeable decrease in the number of indications for surgical lung biopsy. This technique, though simple, has a considerable morbidity and mortality., (Copyright © 2012 Sociedade Portuguesa de Pneumologia. Published by Elsevier España. All rights reserved.)
- Published
- 2013
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16. Coronary heart disease in a patient with cerebrotendinous xanthomatosis.
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Valdivielso P, Calandra S, Durán JC, Garuti R, Herrera E, and González P
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- Adult, Coronary Disease pathology, Family Health, Fatal Outcome, Humans, Knee, Male, Mutation genetics, Skin pathology, Xanthomatosis, Cerebrotendinous genetics, Xanthomatosis, Cerebrotendinous pathology, Coronary Disease complications, Xanthomatosis, Cerebrotendinous complications
- Abstract
Coronary heart disease is a prevalent condition and a leading cause of death in developed countries. Most cases are due to the cluster of classical risk factors, such as smoking, diabetes, high blood pressure and dyslipidaemia. However, a few patients develop severe and premature arteriosclerosis in spite of absence of common risk factors. Here, we present the clinical, analytical and molecular features of a 36-years-old man who died from advanced ischaemic heart disease as a result of cerebrotendinous xanthomatosis (CTX), a rare condition characterized by elevation in plasma and most tissues of cholestanol and where neurological impairment is the hallmark of this disease. We discuss the relevance of heart disease and the mechanism leading to accelerate arteriosclerosis is CTX.
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- 2004
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17. Coronary revascularization with the descending branch of the lateral femoral circumflex artery as a composite arterial graft.
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Schamún CM, Durán JC, Rodríguez JM, Rodríguez M, Sanguinetti CM, Braccini G, and Zorzano F
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- Coronary Angiography, Coronary Disease diagnostic imaging, Coronary Disease mortality, Female, Follow-Up Studies, Humans, Male, Middle Aged, Postoperative Complications diagnostic imaging, Postoperative Complications mortality, Survival Rate, Arteries transplantation, Coronary Artery Bypass methods, Coronary Disease surgery
- Published
- 1998
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18. Comparative optical analysis of cylindrical solar concentrators.
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Durán JC and Nicolás RO
- Abstract
A comparison of the intensity distribution in the receiver plane for five different types of cylindrical concentrators is made. To this end, our previous 2-D optical analysis for nonperfect concentrators with plane receivers is used. Values of the local and mean concentration factors for a characteristic set of parameters of each concentrator are obtained and compared. The results show that the cylindrical-parabolic concentrator attains the highest concentration factors among the concentrators considered.
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- 1987
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19. Heterojunction band offsets and the interface dielectric function.
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Durán JC, Flores F, Tejedor C, and Munoz A
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- 1987
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20. Initial stages of the Schottky-barrier formation for an abrupt Al-GaAs(100) interface.
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Durán JC, Platero G, and Flores F
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- 1986
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21. Theoretical calculation for a ZnSe-Ge(110) heterojunction with an ultrathin intralayer.
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Durán JC, Muoz A, and Flores F
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- 1987
- Full Text
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