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2. Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Kassebaum, Nicholas J, Bertozzi-Villa, Amelia, Coggeshall, Megan S, Shackelford, Katya A, Steiner, Caitlyn, Heuton, Kyle R, Gonzalez-Medina, Diego, Barber, Ryan, Huynh, Chantal, Dicker, Daniel, Templin, Tara, Wolock, Timothy M, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Abera, Semaw Ferede, Abubakar, Ibrahim, Achoki, Tom, Adelekan, Ademola, Ademi, Zanfina, Adou, Arsène Kouablan, Adsuar, José C, Agardh, Emilie E, Akena, Dickens, Alasfoor, Deena, Alemu, Zewdie Aderaw, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Al Kahbouri, Mazin J, Alla, François, Allen, Peter J, AlMazroa, Mohammad A, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzmán, Nelson, Amankwaa, Adansi A, Amare, Azmeraw T, Amini, Hassan, Ammar, Walid, Antonio, Carl A T, Anwari, Palwasha, Ärnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Ali, Asad, Majed Masoud, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Badawi, Alaa, Balakrishnan, Kalpana, Basu, Arindam, Basu, Sanjay, Beardsley, Justin, Bedi, Neeraj, Bekele, Tolesa, Bell, Michelle L, Bernabe, Eduardo, Beyene, Tariku J, Bhutta, Zulfiqar, Bin Abdulhak, Aref, Blore, Jed D, Basara, Berrak Bora, Bose, Dipan, Breitborde, Nicholas, Cárdenas, Rosario, Castañeda-Orjuela, Carlos A, Castro, Ruben Estanislao, Catalá-López, Ferrán, Cavlin, Alanur, Chang, Jung-Chen, Che, Xuan, Christophi, Costas A, Chugh, Sumeet S, Cirillo, Massimo, Colquhoun, Samantha M, Cooper, Leslie Trumbull, Cooper, Cyrus, da Costa Leite, Iuri, Dandona, Lalit, Dandona, Rakhi, Davis, Adrian, Dayama, Anand, Degenhardt, Louisa, De Leo, Diego, del Pozo-Cruz, Borja, Deribe, Kebede, Dessalegn, Muluken, deVeber, Gabrielle A, Dharmaratne, Samath D, Dilmen, Uğur, Ding, Eric L, Dorrington, Rob E, Driscoll, Tim R, Ermakov, Sergei Petrovich, Esteghamati, Alireza, Faraon, Emerito Jose A, Farzadfar, Farshad, Felicio, Manuela Mendonca, Fereshtehnejad, Seyed-Mohammad, de Lima, Graça Maria Ferreira, Forouzanfar, Mohammad H, França, Elisabeth B, Gaffikin, Lynne, Gambashidze, Ketevan, Gankpé, Fortuné Gbètoho, Garcia, Ana C, Geleijnse, Johanna M, Gibney, Katherine B, Giroud, Maurice, Glaser, Elizabeth L, Goginashvili, Ketevan, Gona, Philimon, González-Castell, Dinorah, Goto, Atsushi, Gouda, Hebe N, Gugnani, Harish Chander, Gupta, Rahul, Gupta, Rajeev, Hafezi-Nejad, Nima, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Hankey, Graeme J, Harb, Hilda L, Havmoeller, Rasmus, Hay, Simon I, Pi, Ileana B Heredia, Hoek, Hans W, Hosgood, H Dean, Hoy, Damian G, Husseini, Abdullatif, Idrisov, Bulat T, Innos, Kaire, Inoue, Manami, Jacobsen, Kathryn H, Jahangir, Eiman, Jee, Sun Ha, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B, Juel, Knud, Kabagambe, Edmond Kato, Kan, Haidong, Karam, Nadim E, Karch, André, Karema, Corine Kakizi, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre Pascal, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz Ahmed, Khang, Young-Ho, Knibbs, Luke, Kokubo, Yoshihiro, Kosen, Soewarta, Defo, Barthelemy Kuate, Kulkarni, Chanda, Kulkarni, Veena S, Kumar, G Anil, Kumar, Kaushalendra, Kumar, Ravi B, Kwan, Gene, Lai, Taavi, Lalloo, Ratilal, Lam, Hilton, Lansingh, Van C, Larsson, Anders, Lee, Jong-Tae, Leigh, James, Leinsalu, Mall, Leung, Ricky, Li, Xiaohong, Li, Yichong, Li, Yongmei, Liang, Juan, Liang, Xiaofeng, Lim, Stephen S, Lin, Hsien-Ho, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, London, Stephanie J, Lotufo, Paulo A, Ma, Jixiang, Ma, Stefan, Machado, Vasco Manuel Pedro, Mainoo, Nana Kwaku, Majdan, Marek, Mapoma, Christopher Chabila, Marcenes, Wagner, Marzan, Melvin Barrientos, Mason-Jones, Amanda J, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mills, Edward J, Mokdad, Ali H, Mola, Glen Liddell, Monasta, Lorenzo, de la Cruz Monis, Jonathan, Hernandez, Julio Cesar Montañez, Moore, Ami R, Moradi-Lakeh, Maziar, Mori, Rintaro, Mueller, Ulrich O, Mukaigawara, Mitsuru, Naheed, Aliya, Naidoo, Kovin S, Nand, Devina, Nangia, Vinay, Nash, Denis, Nejjari, Chakib, Nelson, Robert G, Neupane, Sudan Prasad, Newton, Charles R, Ng, Marie, Nieuwenhuijsen, Mark J, Nisar, Muhammad Imran, Nolte, Sandra, Norheim, Ole F, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O, Omer, Saad B, Opio, John Nelson, Orisakwe, Orish Ebere, Pandian, Jeyaraj D, Papachristou, Christina, Park, Jae-Hyun, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris Igor, Pearce, Neil, Pereira, David M, Pesudovs, Konrad, Petzold, Max, Poenaru, Dan, Polanczyk, Guilherme V, Polinder, Suzanne, Pope, Dan, Pourmalek, Farshad, Qato, Dima, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, ur Rahman, Sajjad, Raju, Murugesan, Rana, Saleem M, Refaat, Amany, Ronfani, Luca, Roy, Nobhojit, Pimienta, Tania Georgina Sánchez, Sahraian, Mohammad Ali, Salomon, Joshua A, Sampson, Uchechukwu, Santos, Itamar S, Sawhney, Monika, Sayinzoga, Felix, Schneider, Ione J C, Schumacher, Austin, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shakh-Nazarova, Marina, Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shiue, Ivy, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Andrea P, Singh, Jasvinder A, Skirbekk, Vegard, Sliwa, Karen, Soshnikov, Sergey S, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stroumpoulis, Konstantinos, Sturua, Lela, Sykes, Bryan L, Tabb, Karen M, Talongwa, Roberto Tchio, Tan, Feng, Teixeira, Carolina Maria, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Thorne-Lyman, Andrew L, Tirschwell, David L, Towbin, Jeffrey A, Tran, Bach X, Tsilimbaris, Miltiadis, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen Begüm, Vallely, Andrew J, van Gool, Coen H, Vasankari, Tommi J, Vavilala, Monica S, Venketasubramanian, N, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Vos, Theo, Waller, Stephen, Wang, Haidong, Wang, Linhong, Wang, XiaoRong, Wang, Yanping, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Westerman, Ronny, Wilkinson, James D, Woldeyohannes, Solomon Meseret, Wong, John Q, Wordofa, Muluemebet Abera, Xu, Gelin, Yang, Yang C, Yano, Yuichiro, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zou, Xiao Nong, Lopez, Alan D, Naghavi, Mohsen, Murray, Christopher J L, and Lozano, Rafael

Published
2014
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3. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Murray, Christopher J L, Ortblad, Katrina F, Guinovart, Caterina, Lim, Stephen S, Wolock, Timothy M, Roberts, D Allen, Dansereau, Emily A, Graetz, Nicholas, Barber, Ryan M, Brown, Jonathan C, Wang, Haidong, Duber, Herbert C, Naghavi, Mohsen, Dicker, Daniel, Dandona, Lalit, Salomon, Joshua A, Heuton, Kyle R, Foreman, Kyle, Phillips, David E, Fleming, Thomas D, Flaxman, Abraham D, Phillips, Bryan K, Johnson, Elizabeth K, Coggeshall, Megan S, Abd-Allah, Foad, Abera, Semaw Ferede, Abraham, Jerry P, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen Me, Achoki, Tom, Adeyemo, Austine Olufemi, Adou, Arsène Kouablan, Adsuar, José C, Agardh, Emilie Elisabet, Akena, Dickens, Al Kahbouri, Mazin J, Alasfoor, Deena, Albittar, Mohammed I, Alcalá-Cerra, Gabriel, Alegretti, Miguel Angel, Alemu, Zewdie Aderaw, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francois, Allen, Peter J, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amankwaa, Adansi A, Amare, Azmeraw T, Amini, Hassan, Ammar, Walid, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Ärnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Ali, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Badawi, Alaa, Balakrishnan, Kalpana, Banerjee, Amitava, Basu, Sanjay, Beardsley, Justin, Bekele, Tolesa, Bell, Michelle L, Bernabe, Eduardo, Beyene, Tariku Jibat, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Abdulhak, Aref Bin, Binagwaho, Agnes, Blore, Jed D, Basara, Berrak Bora, Bose, Dipan, Brainin, Michael, Breitborde, Nicholas, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Chadha, Vineet K, Chang, Jung-Chen, Chiang, Peggy Pei-Chia, Chuang, Ting-Wu, Colomar, Mercedes, Cooper, Leslie Trumbull, Cooper, Cyrus, Courville, Karen J, Cowie, Benjamin C, Criqui, Michael H, Dandona, Rakhi, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Deribe, Kebede, Des Jarlais, Don C, Dessalegn, Muluken, Dharmaratne, Samath D, Dilmen, Uğur, Ding, Eric L, Driscoll, Tim R, Durrani, Adnan M, Ellenbogen, Richard G, Ermakov, Sergey Petrovich, Esteghamati, Alireza, Faraon, Emerito Jose A, Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fijabi, Daniel Obadare, Forouzanfar, Mohammad H, Fra.Paleo, Urbano, Gaffikin, Lynne, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Ginawi, Ibrahim Abdelmageem Mohamed, Glaser, Elizabeth L, Gona, Philimon, Goto, Atsushi, Gouda, Hebe N, Gugnani, Harish Chander, Gupta, Rajeev, Gupta, Rahul, Hafezi-Nejad, Nima, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Hankey, Graeme J, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Simon I, Hedayati, Mohammad T, Pi, Ileana B Heredia, Hoek, Hans W, Hornberger, John C, Hosgood, H Dean, Hotez, Peter J, Hoy, Damian G, Huang, John J, Iburg, Kim M, Idrisov, Bulat T, Innos, Kaire, Jacobsen, Kathryn H, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B, Juel, Knud, Kan, Haidong, Kankindi, Ida, Karam, Nadim E, Karch, André, Karema, Corine Kakizi, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz Ahmed, Khang, Young-Ho, Khonelidze, Irma, Kinfu, Yohannes, Kinge, Jonas M, Knibbs, Luke, Kokubo, Yoshihiro, Kosen, S, Defo, Barthelemy Kuate, Kulkarni, Veena S, Kulkarni, Chanda, Kumar, Kaushalendra, Kumar, Ravi B, Kumar, G Anil, Kwan, Gene F, Lai, Taavi, Balaji, Arjun Lakshmana, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larson, Heidi J, Larsson, Anders, Lee, Jong-Tae, Leigh, James, Leinsalu, Mall, Leung, Ricky, Li, Yichong, Li, Yongmei, De Lima, Graça Maria Ferreira, Lin, Hsien-Ho, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Lotufo, Paulo A, Machado, Vasco Manuel Pedro, Maclachlan, Jennifer H, Magis-Rodriguez, Carlos, Majdan, Marek, Mapoma, Christopher Chabila, Marcenes, Wagner, Marzan, Melvin Barrientos, Masci, Joseph R, Mashal, Mohammad Taufiq, Mason-Jones, Amanda J, Mayosi, Bongani M, Mazorodze, Tasara T, Mckay, Abigail Cecilia, Meaney, Peter A, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Melaku, Yohannes Adama, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mills, Edward J, Mohammad, Karzan Abdulmuhsin, Mokdad, Ali H, Mola, Glen Liddell, Monasta, Lorenzo, Montico, Marcella, Moore, Ami R, Mori, Rintaro, Moturi, Wilkister Nyaora, Mukaigawara, Mitsuru, Murthy, Kinnari S, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nangia, Vinay, Narayan, K M Venkat, Nash, Denis, Nejjari, Chakib, Nelson, Robert G, Neupane, Sudan Prasad, Newton, Charles R, Ng, Marie, Nisar, Muhammad Imran, Nolte, Sandra, Norheim, Ole F, Nowaseb, Vincent, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O, Omer, Saad B, Opio, John Nelson, Orisakwe, Orish Ebere, Pandian, Jeyaraj D, Papachristou, Christina, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris Igor, Pearce, Neil, Pereira, David M, Pervaiz, Aslam, Pesudovs, Konrad, Petzold, Max, Pourmalek, Farshad, Qato, Dima, Quezada, Amado D, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad Ur, Raju, Murugesan, Rana, Saleem M, Razavi, Homie, Reilly, Robert Quentin, Remuzzi, Giuseppe, Richardus, Jan Hendrik, Ronfani, Luca, Roy, Nobhojit, Sabin, Nsanzimana, Saeedi, Mohammad Yahya, Sahraian, Mohammad Ali, Samonte, Genesis May J, Sawhney, Monika, Schneider, Ione J C, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shiue, Ivy, Shivakoti, Rupak, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Andrea P, Simard, Edgar P, Singh, Jasvinder A, Skirbekk, Vegard, Sliwa, Karen, Soneji, Samir, Soshnikov, Sergey S, Sreeramareddy, Chandrashekhar T, Stathopoulou, Vasiliki Kalliopi, Stroumpoulis, Konstantinos, Swaminathan, Soumya, Sykes, Bryan L, Tabb, Karen M, Talongwa, Roberto Tchio, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Towbin, Jeffrey A, Traebert, Jefferson, Tran, Bach X, Dimbuene, Zacharie Tsala, Tsilimbaris, Miltiadis, Uchendu, Uche S, Ukwaja, Kingsley N, Uzun, Selen Begüm, Vallely, Andrew J, Vasankari, Tommi J, Venketasubramanian, N, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Waller, Stephen, Wallin, Mitchell T, Wang, Linhong, Wang, XiaoRong, Wang, Yanping, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Westerman, Ronny, White, Richard A, Wilkinson, James D, Williams, Thomas Neil, Woldeyohannes, Solomon Meseret, Wong, John Q, Xu, Gelin, Yang, Yang C, Yano, Yuichiro, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zou, Xiao Nong, Lopez, Alan D, and Vos, Theo

Published
2014
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4. Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Wang, Haidong, Liddell, Chelsea A, Coates, Matthew M, Mooney, Meghan D, Levitz, Carly E, Schumacher, Austin E, Apfel, Henry, Iannarone, Marissa, Phillips, Bryan, Lofgren, Katherine T, Sandar, Logan, Dorrington, Rob E, Rakovac, Ivo, Jacobs, Troy A, Liang, Xiaofeng, Zhou, Maigeng, Zhu, Jun, Yang, Gonghuan, Wang, Yanping, Liu, Shiwei, Li, Yichong, Ozgoren, Ayse Abbasoglu, Abera, Semaw Ferede, Abubakar, Ibrahim, Achoki, Tom, Adelekan, Ademola, Ademi, Zanfina, Alemu, Zewdie Aderaw, Allen, Peter J, AlMazroa, Mohammad AbdulAziz, Alvarez, Elena, Amankwaa, Adansi A, Amare, Azmeraw T, Ammar, Walid, Anwari, Palwasha, Cunningham, Solveig Argeseanu, Asad, Majed Masoud, Assadi, Reza, Banerjee, Amitava, Basu, Sanjay, Bedi, Neeraj, Bekele, Tolesa, Bell, Michelle L, Bhutta, Zulfiqar, Blore, Jed D, Basara, Berrak Bora, Boufous, Soufiane, Breitborde, Nicholas, Bruce, Nigel G, Bui, Linh Ngoc, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Caso, Valeria, Castro, Ruben Estanislao, Catalá-Lopéz, Ferrán, Cavlin, Alanur, Che, Xuan, Chiang, Peggy Pei-Chia, Chowdhury, Rajiv, Christophi, Costas A, Chuang, Ting-Wu, Cirillo, Massimo, da Costa Leite, Iuri, Courville, Karen J, Dandona, Lalit, Dandona, Rakhi, Davis, Adrian, Dayama, Anand, Deribe, Kebede, Dharmaratne, Samath D, Dherani, Mukesh K, Dilmen, Uğur, Ding, Eric L, Edmond, Karen M, Ermakov, Sergei Petrovich, Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fijabi, Daniel Obadare, Foigt, Nataliya, Forouzanfar, Mohammad H, Garcia, Ana C, Geleijnse, Johanna M, Gessner, Bradford D, Goginashvili, Ketevan, Gona, Philimon, Goto, Atsushi, Gouda, Hebe N, Green, Mark A, Greenwell, Karen Fern, Gugnani, Harish Chander, Gupta, Rahul, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Harb, Hilda L, Hay, Simon, Hedayati, Mohammad T, Hosgood, H Dean, Hoy, Damian G, Idrisov, Bulat T, Islami, Farhad, Ismayilova, Samaya, Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B, Juel, Knud, Kabagambe, Edmond Kato, Kazi, Dhruv S, Kengne, Andre Pascal, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khang, Young-Ho, Kim, Daniel, Kinfu, Yohannes, Kinge, Jonas M, Kokubo, Yoshihiro, Kosen, Soewarta, Defo, Barthelemy Kuate, Kumar, G Anil, Kumar, Kaushalendra, Kumar, Ravi B, Lai, Taavi, Lan, Qing, Larsson, Anders, Lee, Jong-Tae, Leinsalu, Mall, Lim, Stephen S, Lipshultz, Steven E, Logroscino, Giancarlo, Lotufo, Paulo A, Lunevicius, Raimundas, Lyons, Ronan Anthony, Ma, Stefan, Mahdi, Abbas Ali, Marzan, Melvin Barrientos, Mashal, Mohammad Taufiq, Mazorodze, Tasara T, McGrath, John J, Memish, Ziad A, Mendoza, Walter, Mensah, George A, Meretoja, Atte, Miller, Ted R, Mills, Edward J, Mohammad, Karzan Abdulmuhsin, Mokdad, Ali H, Monasta, Lorenzo, Montico, Marcella, Moore, Ami R, Moschandreas, Joanna, Msemburi, William T, Mueller, Ulrich O, Muszynska, Magdalena M, Naghavi, Mohsen, Naidoo, Kovin S, Narayan, KM Venkat, Nejjari, Chakib, Ng, Marie, de Dieu Ngirabega, Jean, Nieuwenhuijsen, Mark J, Nyakarahuka, Luke, Ohkubo, Takayoshi, Omer, Saad B, Caicedo, Angel J Paternina, Wyk, Victoria Pillay-van, Pope, Dan, Pourmalek, Farshad, Prabhakaran, Dorairaj, Rahman, Sajjad UR, Rana, Saleem M, Reilly, Robert Quentin, Rojas-Rueda, David, Ronfani, Luca, Rushton, Lesley, Saeedi, Mohammad Yahya, Salomon, Joshua A, Sampson, Uchechukwu, Santos, Itamar S, Sawhney, Monika, Schmidt, Jürgen C, Shakh-Nazarova, Marina, She, Jun, Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shishani, Kawkab, Shiue, Ivy, Sigfusdottir, Inga Dora, Singh, Jasvinder A, Skirbekk, Vegard, Sliwa, Karen, Soshnikov, Sergey S, Sposato, Luciano A, Stathopoulou, Vasiliki Kalliopi, Stroumpoulis, Konstantinos, Tabb, Karen M, Talongwa, Roberto Tchio, Teixeira, Carolina Maria, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Toyoshima, Hideaki, Dimbuene, Zacharie Tsala, Uwaliraye, Parfait, Uzun, Selen Begüm, Vasankari, Tommi J, Vasconcelos, Ana Maria Nogales, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Waller, Stephen, Wan, Xia, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Westerman, Ronny, Wilkinson, James D, Williams, Hywel C, Yang, Yang C, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Younis, Mustafa, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhu, Shankuan, Vos, Theo, Lopez, Alan D, and Murray, Christopher J L

Published
2014
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13. Marmaris Declaration: Ethical Concepts of Right to life and Pre-viability

Author

AKŞİT, M. Arif, DAĞOĞLU, Türkan, DİLMEN, Uğur, and ÖRS, Rahmi

Subjects
Pediatri, Pre-viability,Right to life, Pediatrics
Abstract

Ethical principles are mainly constructed under the “human rights” concepts, and ethics as aphilosophical aspect under medical perspective, try to find the answer of “what is right” and“ought to do” for the special condition or case/patient. Consider or treat the human not thedisease will be our aim with empathic approach.

Published
2020

25. Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Author

Yoshida, Sachiyo, Martines, José, Lawn, Joy E, Wall, Stephen, Souza, Joăo Paulo, Rudan, Igor, Cousens, Simon, Aaby, Peter, Adam, Ishag, Adhikari, Ramesh Kant, Ambalavanan, Namasivayam, Arifeen, Shams Ei, Aryal, Dhana Raj, Asiruddin, Sk, Baqui, Abdullah, Barros, Aluisio Jd, Benn, Christine S, Bhandari, Vineet, Bhatnagar, Shinjini, Bhattacharya, Sohinee, Bhutta, Zulfiqar A, Black, Robert E, Blencowe, Hannah, Bose, Carl, Brown, Justin, Bührer, Christoph, Carlo, Wally, Cecatti, Jose Guilherme, Cheung, Po-Yin, Clark, Robert, Colbourn, Tim, Conde-Agudelo, Agustin, Corbett, Erica, Czeizel, Andrew E, Das, Abhik, Day, Louise Tina, Deal, Carolyn, Deorari, Ashok, Dilmen, Uğur, English, Mike, Engmann, Cyril, Esamai, Fabian, Fall, Caroline, Ferriero, Donna M, Gisore, Peter, Hazir, Tabish, Higgins, Rosemary D, Homer, Caroline Se, Hoque, D E, and Irgens, Lorentz

Abstract

BACKGROUND: In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025.METHODS: We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts.RESULTS: Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour.CONCLUSION: These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.

Published
2016

26. Hydrops Fetalis due to Kell Alloimmunization: A Perinatal Approach to a Rare Case

Author

Akdağ, Arzu, Erdeve, Ömer, Uraş, Nurdan, Şimşek, Yavuz, and Dilmen, Uğur

Subjects
newborn, Case Report, Anemia, Hydrops fetalis, Kell alloimmunization
Abstract

Objective: While routine administration of rhesus (Rh) immunoglobulin has significantly reduced the incidence of Rh alloimmunization, maternal alloimmunization to other red cell antigens remains a contributor to perinatal morbidity and mortality. Although the Kell antigen is seen on the red cells of only 9% of the general population, attention to Kell antibodies continues to increase. Case Report: A case of fetal hydrops was sonographically detected at 30 weeks of gestation. Antenatal tests to evaluate the fetus’s condition clearly showed that the level of hemolytic disease was critical and the baby was delivered prematurely due to fetal distress. The combination of anemia, reticulocytopenia, hydrops fetalis, and a positive indirect Coombs test suggested Kell isoimmunization. The baby was successfully treated with exchange transfusion of Kellnegative packed red cells, and was discharged on postnatal d 30. Conclusion: The presented case of hydrops fetalis was due Kell alloimmunization that was detected during the postnatal period, and thus we plan to discuss the perinatal approach to Kell immunization.

Published
2012

27. Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Author

Yoshida, Sachiyo, Martines, José, Lawn, Joy E, Wall, Stephen, Souza, Joăo Paulo, Rudan, Igor, Cousens, Simon, neonatal health research priority setting group, Aaby, Peter, Adam, Ishag, Adhikari, Ramesh Kant, Ambalavanan, Namasivayam, Arifeen, Shams Ei, Aryal, Dhana Raj, Asiruddin, Sk, Baqui, Abdullah, Barros, Aluisio Jd, Benn, Christine S, Bhandari, Vineet, Bhatnagar, Shinjini, Bhattacharya, Sohinee, Bhutta, Zulfiqar A, Black, Robert E, Blencowe, Hannah, Bose, Carl, Brown, Justin, Bührer, Christoph, Carlo, Wally, Cecatti, Jose Guilherme, Cheung, Po-Yin, Clark, Robert, Colbourn, Tim, Conde-Agudelo, Agustin, Corbett, Erica, Czeizel, Andrew E, Das, Abhik, Day, Louise Tina, Deal, Carolyn, Deorari, Ashok, Dilmen, Uğur, English, Mike, Engmann, Cyril, Esamai, Fabian, Fall, Caroline, Ferriero, Donna M, Gisore, Peter, Hazir, Tabish, Higgins, Rosemary D, Homer, Caroline Se, Hoque, DE, Irgens, Lorentz, Islam, MT, de Graft-Johnson, Joseph, Joshua, Martias Alice, Keenan, William, Khatoon, Soofia, Kieler, Helle, Kramer, Michael S, Lackritz, Eve M, Lavender, Tina, Lawintono, Laurensia, Luhanga, Richard, Marsh, David, McMillan, Douglas, McNamara, Patrick J, Mol, Ben Willem J, Molyneux, Elizabeth, Mukasa, GK, Mutabazi, Miriam, Nacul, Luis Carlos, Nakakeeto, Margaret, Narayanan, Indira, Olusanya, Bolajoko, Osrin, David, Paul, Vinod, Poets, Christian, Reddy, Uma M, Santosham, Mathuram, Sayed, Rubayet, Schlabritz-Loutsevitch, Natalia E, Singhal, Nalini, Smith, Mary Alice, Smith, Peter G, Soofi, Sajid, Spong, Catherine Y, Sultana, Shahin, Tshefu, Antoinette, van Bel, Frank, Gray, Lauren Vestewig, Waiswa, Peter, Wang, Wei, Williams, Sarah LA, Wright, Linda, Zaidi, Anita, Zhang, Yanfeng, Zhong, Nanbert, Zuniga, Isabel, and Bahl, Rajiv

Subjects
Pediatric, Good Health and Well Being, Preterm, Prevention, Infant Mortality, Public Health and Health Services, neonatal health research priority setting group, Reproductive health and childbirth, Perinatal Period - Conditions Originating in Perinatal Period, Low Birth Weight and Health of the Newborn
Abstract

BACKGROUND: In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025. METHODS: We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts. RESULTS: Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour. CONCLUSION: These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.

Published
2015

28. Fetal Cervical Neuroblastoma: Prenatal Diagnosis

Author

Güzelmansur, Ismail, Aksoy, Hatice Tatar, Hakverdi, Sibel, Seven, Mustafa, Dilmen, Uğur, and Dilmen, Gülçin

Subjects
Article Subject
Abstract

Neuroblastoma is the most frequent extracranial solid tumor in childhood, but it is seldom diagnosed prenatally. It usually presented with adrenal masses. Presentation of other localization is extremely rare. We report a case of cervical neuroblastoma identified at 20 weeks of gestational age. This is the third case diagnosed antenatally on neck region in the literature. Additionally, it is the first case that extended to the brain. We also discussed the literature for cervical neuroblastoma detected prenatally.

Published
2011
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30. Evaluation of bone metabolism in newborn twins using quantitative ultrasound and biochemical parameters.

Author

Kara, Semra, Güzoğlu, Nilüfer, Göçer, Emine, Arıkan, Fatma Inci, Dilmen, Uğur, and Dallar Bilge, Yıldız

Subjects
BONE metabolism, TWINS, NEWBORN infant care, ULTRASONIC imaging, BIOCHEMISTRY, BONES, NEWBORN infants, OSTEOPENIA
Abstract

Metabolic bone disease (MBD) is one of the important complications of prematurity. Early and adequate nutritional interventions may reduce the incidence and potential complications of MBD. The present study aimed to evaluate bone metabolism in twins via biochemical parameters and quantitative ultrasound (QUS) and to compare the results between twin pairs. Moreover, twin infants were evaluated in terms of potential risk factors likely to have impact on MBD. Forty-three pairs of twins were included in the study. Serum calcium, phosphorus, magnesium, and alkaline phosphatase concentrations were assessed and bone mineral density was measured using QUS (speed of sound, SOS) at postnatal 30 d. Co-twin with the higher birth weight was assigned to Group 1 (n = 36) and the other twin was assigned to Group 2 (n = 36). Birth weight and head circumference were significantly higher in the infants of Group 1 compared with Group 2. No significant difference was found among the groups in terms of gender, history of resuscitation, length of stay in intensive care unit (ICU) or in the incubator, duration of total parenteral nutrition (TPN), type of nutrition, vitamin D use, biochemical parameters, and the SOS value. The factors likely to affect SOS, including type of pregnancy, maternal drug use, gender of infant, birth weight, head circumference at birth, gestational week, length of stay at the ICU, duration of TPN, type of nutrition, resuscitation, vitamin D use, and levels of calcium, phosphorus, magnesium, and alkaline phosphatase were entered into the model. The phosphorus level and the maternal drug use were found to be the factors that significantly reduced SOS, whereas pregnancy after assisted reproductive techniques was found to be a significant enhancing factor. [ABSTRACT FROM PUBLISHER]

Published
2016
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31. Zekai Tahir Burak Women's Health Education and Research Hospital newborn hearing screening results and assessment of the patients.

Author

Çelik, İstemi Han, Canpolat, Fuat Emre, Demirel, Gamze, Eras, Zeynep, Sungur, Veli Gençay, Sarıer, Barış, and Dilmen, Uğur

Subjects
ACADEMIC medical centers, AMINOGLYCOSIDES, ARTIFICIAL respiration, ASPHYXIA neonatorum, AUDIOMETRY, AUDITORY evoked response, BIRTH weight, BRAIN stem, FETAL growth retardation, FUROSEMIDE, GESTATIONAL age, HEARING disorders, HYPERBILIRUBINEMIA, HYPOGLYCEMIA, LUNG diseases, MULTIPLE pregnancy, PLASMA exchange (Therapeutics), POLYCYTHEMIA, RESPIRATORY distress syndrome, RETROLENTAL fibroplasia, SEPSIS
Abstract

Aim: Social, emotional, cognitive and language development of infants is provided with early diagnosis of hearing deficit. Hearing deficit is reported with a rate of 1-6 in 1000 live births in healthy newborns, while it reaches up to 10-30 in 1000 live births in newborns with risk factors. We aimed to compile the results of the hearing screening program applied in our hospital. Material and Methods: The records of the hearing screening program were examined and the results were compiled by reaching the records of the patients who were found to have hearing deficit. Results: Hearing test was applied in a total of 142 128 patients between 2005 and 2011. Hearing test was performed by evoked autoaucistic emission for two times in 26 690 of these patients and for three times in 2 412. A diagnosis of hearing deficit was made in 385 patients (0.27%) after application of ARB (Auditory Brainstem Response). The medical records of 171 of the patients who were referred for advanced investigations and treatment were obtained. 116 of these patients had a history of hospitalization in neonatal intensive care unit, while 55 patients had no history of hospitalization in neonatal intensive care unit. 49 of the patients had a gestational age below the 32th week and 122 had a gestational age above the 32th week. The median gestational age and birth weight values and ranges were found to be 35 (22-43) and 2 140 g (580-4 590 g), respectively. The risk factors included intrauterine growth retardation (n=24), multiple pregnancy (n=22), hyperbilirubinemia (n=74), blood exchange because of hyperbilirubinemia (n=7), sepsis (n=52), hypoglycemia (n=2), use of aminoglycoside and glycopeptide (n=99), use of furosemide (n=27), mechanical ventilation therapy (n=37), polycythemia (n=12), prenatal asphyxia (n=2), respiratory distress syndrome (n=45), chronic lung disease (n=11), surgery for retinopathy of prematurity (n=8) and hearing deficit in the mother or father (n=7). Conclusions: In addition to the necessity of performing hearing screening in all newborns, infants with risk factors should be determined, hearing deficit should be screened with repeated hearing tests and social, emotional, cognitive and language development of the infant should be assured. [ABSTRACT FROM AUTHOR]

Published
2014
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32. Early regular versus late selective poractant treatment in preterm infants born between 25 and 30 gestational weeks: a prospective randomized multicenter study.

Author

Dilmen, Uğur, Özdemir, Ramazan, Tatar Aksoy, Hatice, Uras, Nurdan, Demirel, Nihal, Kırimi, Ercan, Erdeve, Ömer, Özer, Esra, Baş, Ahmet Yağmur, Gürsoy, Tuğba, Zenciroğlu, Ayşegül, Ovalı, Fahri, and Oğuz, Ş. Suna

Subjects
*BRONCHOPULMONARY dysplasia, *PNEUMOTHORAX, *PREMATURE labor, *PREMATURE infants, *SURFACE active agents, *THERAPEUTICS
Abstract

Objective: Surfactant treatment in the early hours of life significantly decreases the rates of death and air leak, and increases survival without bronchopulmonary dysplasia (BPD) in preterm infants. We aimed to compare the impact of early surfactant (ES) administration to late selective (LS) treatment on neonatal outcomes in preterm infants. Methods: All preterm infants between 25 and 30 wks gestational age and who were not entubated in the delivery room and did not have any major congenital malformation or perinatal asphyxia were randomized to ES treatment (200 mg/kg Curosurf® administration in 1 hour after birth) or LS treatment (200 mg/kg Curosurf®administration in the first 6 h of life if needed). The patients were treated by nasal continuous positive airway pressure (nCPAP) treatment regardless of the surfactant requirement. Outcomes were the necessity of mechanical ventilation, nCPAP duration, the oxygen requirement duration, the rates of BPD, retinopathy of prematurity (ROP) and mortality, and the assesment of the following situations; (pneumothorax, patent ductus arteriosus (PDA), necrotizing enterocolitis (NEC), and intraventricular hemorrhage (IVH) ≥ grade III). Results: Among 159 infants enrolled in the study, 79 were randomized to ES and 80 to LS treatment groups. Thirty-five patients (44%) in the LS treatment group needed surfactant administration. Necessity of second dose surfactant administration was 8.9% in the ES treatment group. Although necessity of mechanical ventilation, nCPAP duration, oxygen need duration, rates of PDA, NEC, BPD, ROP stage >3 and mortality did not show a significant difference between groups, the ES treatment group had lower rates of pneumothorax and IVH≥ grade III when compared to the LS treatment group. Conclusions: ES treatment decreases IVH (≥ grade III) and pneumothorax rates but does not have any effect on BPD when compared to LS. [ABSTRACT FROM AUTHOR]

Published
2014
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35. Establishment and Development of a National Newborn Screening Programme for Congenital Hypothyroidism in Turkey.

Author

Dilli, Dilek, Özbaş, Sema, Acıcan, Deniz, Yamak, Nergiz, Ertek, Mustafa, and Dilmen, Uğur

Subjects
CONGENITAL hypothyroidism, THYROID diseases, NEWBORN screening, HEALTH programs
Abstract

Objective: To assess the Turkish National Newborn Screening Programme (NNSP) for congenital hypothyroidism (CH). Retrospective study based on the data from NNSP. Methods: Since December 2006, a nationwide screening programme for CH has been conducted in Turkey by the Turkish Directorate of Public Health (TDPH) in cooperation with several institutions. We evaluated the database between January 2008 and July 2010 of this programme. According to the methodology of the NNSP, between three and five days of age (or at discharge from the hospital, if this occurs earlier) blood specimens were routinely collected from neonates on filter paper, by puncturing the heel. The accepted thyroid-stimulating hormone cut-off level for recall was 20 mU/L initially and 15 mU/L subsequently. The incidence of possible CH by years was reported. Results: During the evaluation period, 3223765 newborns were tested. The mean annual incidence of possible CH showed a gradual increase over the years (1:888 in 2008, 1:592 in 2009, and 1:469 in 2010). Regional differences were noted. Although the mean age of blood sampling did not change by years, the mean age at notification for suspected CH decreased from 19.2 to 15.7 days from 2008 to 2010. Conclusions: We reported the first assessment of NNSP in Turkey. An improvement in performance measures for the CH screening programme has been noted. Knowledge on incidence of confirmed CH is not yet available in the database. [ABSTRACT FROM AUTHOR]

Published
2013
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36. A Case of Nonimmune Hydrops Fetalis Caused by Homozygous α-Thalassemia.

Author

Akar, Melek, Dilli, Dilek, and Dilmen, Uğur

Subjects
EDEMA, FETAL diseases, ALPHA-Thalassemia, DISEASE complications
Abstract

Copyright of Turkish Journal of Hematology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2013
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37. Respiratory syncytial virus prophylaxis in preterm infants: a cost-effectiveness study from Turkey.

Author

Öncel, Mehmet Yekta, Mutlu, Banu, Kavurt, Sumru, Baş, Ahmet Yağmur, Demirel, Nihal, Akyol, Mesut, Erdeve, Ömer, and Dilmen, Uğur

Abstract

The main aim of this study was to evaluate the cost-effectiveness of respiratory syncytial virus (RSV) prophylaxis with palivizumab in Turkey, by comparing hospitalization rates and costs as well as results of risk analyses in preterm infants who were treated either with palivizumab or conservatively. This retrospective study was undertaken in two centers on infants born with a gestational age of ≤32 weeks during the 2010-2011 seasons. Patients were divided into two groups based on status of RSV prophylaxis. The records of 272 infants were included in the final analysis, 201 (73.9%) of which had received palivizumab (Group 1), while 71 (26.1%) were not given any form of RSV prophylaxis. The difference between groups in terms of demographic characteristics and risk factors for RSV infection was statistically insignificant (p>0.05). Thirteen patients (6.5%) in Group 1 and 5 patients (7%) in Group 2 were hospitalized for lower respiratory tract infections (LRTIs) (p>0.05). In newborns born at ≤286/7 weeks of gestation, RSV prophylaxis with palivizumab was associated with a 38.75% decrease in hospitalization rates due to LRTIs compared to the untreated group (8% in the untreated group vs. 4.9% in the palivizumab group; p=0.577). The hospitalization rate due to LRTIs for infants in Group 1 born after 29-32 weeks of gestation was 7.5% compared to a rate of 6.5% in Group 2, with a statistically insignificant difference (p=0.828). In infants with bronchopulmonary dysplasia (BPD) born at ≤286/7 weeks of gestation, treatment with palivizumab was associated with a 39.1% decrease in LRTI-related hospitalization rates (14.3% in the untreated group vs. 8.7% in the palivizumab group; p=0.677). This clinical study is the first of its kind from Turkey to evaluate the cost-effectiveness of palivizumab treatment as prophylaxis against RSV infections in preterm infants, where hospitalization rates and costs of patients treated with palivizumab were compared with those of infants who were treated conservatively. Our study results suggest that administration of palivizumab does not have any cost benefit, regardless of gestational age. However, a reduction in hospitalization rates in association with palivizumab treatment was observed in infants born at ≤286/7 weeks of gestation with or without BPD. [ABSTRACT FROM AUTHOR]

Published
2012

38. The Role of Interleukin-6 and C-Reactive Protein in Non-Thyroidal Illness in Premature Infants Followed in Neonatal Intensive Care Unit.

Author

Dilli, Dilek and Dilmen, Uğur

Subjects
*INTERLEUKIN-6, *C-reactive protein, *PREMATURE infant diseases, *NEONATAL intensive care, *SEPSIS
Abstract

Objective: To investigate the role of interleukin-6 (IL-6) and C-reactive protein (CRP) in non-thyroidal illness (NTI) in premature infants. Methods: Serum levels of IL-6 and CRP, thyroid-stimulating hormone (TSH), total thyroxine (T4), free T4 (fT4), total triiodothyronine (T3), and free T3 (fT3) were determined at the 1st, 2nd and 4th weeks of postnatal life in 148 premature infants born before 33 weeks of gestation. Results: At the 1st week, serum T3 was negatively correlated with IL-6 (r= -0.33, p= 0.001) and CRP (r= -0.17, p= 0.03). Serum T3 was negatively and more strongly correlated with IL-6 (r= -0.49, p= 0.001) and CRP (r=- 0.33, p= 0.03) at the 2nd week, at which time sepsis frequency and low T3 rates were the highest. At the 4th week, mortality rate was higher among infants with lower T3 levels. Conclusions: High IL-6 and CRP values related to neonatal sepsis might have a significant role in the pathogenesis of NTI in premature infants. [ABSTRACT FROM AUTHOR]

Published
2012
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39. The effects of immersion in water on labor, birth and newborn and comparison with epidural analgesia and conventional vaginal delivery.

Author

Mollamahmutoğlu, Leyla, Moraloğlu, Özlem, Özyer, Şebnem, Su, Filiz Akın, Karayalçın, Rana, Hançerlioğlu, Necati, Uzunlar, Özlem, and Dilmen, Uğur

Subjects
EPIDURAL analgesia, ANALYSIS of variance, APGAR score, CHI-squared test, DELIVERY (Obstetrics), EVALUATION of medical care, NEONATAL intensive care, PREGNANCY, STATISTICS, UNDERWATER childbirth, VAGINA, DATA analysis, NEONATAL intensive care units, VISUAL analog scale, DATA analysis software
Abstract

Copyright of Journal of the Turkish-German Gynecological Association is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2012
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41. Tm vcut soğutma yntemi ile hipotermi uygulanan hipoksik iskemik ansefalopatili yenidoğanların değerlendirilmesi.

Author

Akar, Melek, Aydemir, zge, Oğuz, Şerife Suna, Erdeve, mer, Aydemir, Cumhur, Gkmen, Tlin, Eras, Zeynep, Uraş, Nurdan, and Dilmen, Uğur

Subjects
CEREBRAL anoxia-ischemia, ELECTROENCEPHALOGRAPHY, CLINICAL trials, HYPOTHERMIA, INFANT mortality, HEALTH outcome assessment, SCALES (Weighing instruments), TREATMENT effectiveness, THERAPEUTICS
Abstract

Aim: To investigate the effect of whole body hypothermia on short term neonatal morbidities and long term neurodevelopmental outcome in term neonates with hypoxic ischemic encephalopathy. Material and Method: Neonates with perinatal asphyxia and hypoxic ischemic encepholopathy (stage 2 and 3) were enrolled. Patients were divided into 2 groups according to findings observed on amplitude-integrated electroencephalography (aEEG). Patients with abnormal aEEG pattern in the first six hours after birth were defined as group 1 and others as group 2. Patients in group 1 were treated with whole body hypothermia. Neurodevelopmental outcome was evaluated at 18 months of age in survivors using Bayley Scales of Infant Development II. Mental developmental index and psychomotor development index scores were calculated. Results: Thirty five patients were enrolled (M/F=17/18), 18 (51%) of whom were treated with hypothermia. Bradycardia was observed in 44.4% of patients in group 1 and 5.9% of patients in group 2 (p=0.04). Incidence of other possible adverse events related to hypothermia were similar between the two groups. Mortality was higher in group 1 (p=0.03). In group 1, 70% of the patients and in group 2, 86% of the patients were evaluated using Bayley Scales of Infant Development II. Although patients treated with hypothermia had a higher mental developmental index and psychomotor development index scores, the difference was not statistically significant. Conclusions: Whole body hypothermia can be safely applied in term neonates with HIE. Hypothermia may improve neurodevelopmental outcome. [ABSTRACT FROM AUTHOR]

Published
2011
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42. Multiple large brain abscesses in a newborn that may have resulted from intrauterine infection.

Author

Çelik, İstemi Han, Demirel, Gamze, Erdeve, Ömer, Uraş, Nurdan, and Dilmen, Uğur

Abstract

Brain abscess is a focal, intracerebral infection that begins as a localized area of cerebritis and develops into a collection of pus surrounded by a well-vascularized capsule. Here, we report a case with multiple, large brain abscesses diagnosed coincidentally on postnatal day 11. This case is noteworthy because the organized abscesses were present as early as day 11 with no significant neurological signs or symptoms. Brain abscess in newborns is a very rare disease that may not exhibit the expected neurological signs and symptoms. Depending on the radiological organization, an abscess in a neonate in the first weeks may be the result of an intrauterine infection. [ABSTRACT FROM AUTHOR]

Published
2011

44. Serum Thyroid Hormone Levels in Preterm Infants Born before 33 Weeks of Gestation and Association of Transient Hypothyroxinemia with Postnatal Characteristics.

Author

Dilli, Dilek, Oğuz, Ş. Suna, Andıran, Nesibe, Dilmen, Uğur, and Büyükkağnıcı, Ümran

Abstract

The article provides information on a study which evaluated the reference values of serum thyroid hormones in preterm infants born before 33 week gestation. The study also defined a cut-off value for transient hypothyroxinemia of prematurity (THOP) based on gestational age and relationship of THOP with postnatal characteristics in these infants. A review of the related literature on THOP is offered. Data collection was done between March 2008 and February 2009 at the Ministry of Health Zekai Tahir Burak Maternity and Teaching Hospital in Turkey.

Published
2010
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46. Effect of passive smoking on growth and infection rates of breast-fed and non-breast-fed infants.

Author

Yılmaz, Gonca, Hızlı, Şamil, Karacan, Candemir, Yurdakök, Kadriye, Coşkun, Turgay, and Dilmen, Uğur

Subjects
PASSIVE smoking in infants, RESPIRATORY infections in children, BREASTFEEDING, OTITIS media in children, CROSS-sectional method, MULTIVARIATE analysis, DISEASE risk factors, IMMUNOLOGY
Abstract

Background: The aim of the present study was to determine the effect of passive tobacco smoking on growth and infection rate of infants, and to evaluate whether breast-feeding might be protective against harmful effects of cigarette smoke. Methods: A cross-sectional study on 254 6–7-month-old infants was carried out. A questionnaire was given to mothers; and infants’ head circumference, bodyweight, height, and urinary cotinine levels were measured. Results: Multivariate analysis of factors influencing lower respiratory tract infections showed that smoking mothers increased the rate by 9.1-fold; breast-feeding decreased it by 3.3-fold; formula feeding at birth increased it by a factor of 15.2; another smoker at home increased it by a factor of 40.1. Multivariate analysis of factors influencing upper respiratory tract infections showed that smoking mothers increased the rate by a factor of 23; early formula feeding increased it by a factor of 62; breast-feeding decreased it by a factor of 5; smoking fathers increased it by a factor of 15. Multivariate analysis of factors influencing otitis media found that smoking mothers and fathers increased it by a factor of 9.4 and 6.15, respectively, and breast-feeding decreased it by a factor of 5.4. Conclusion: Tobacco smoke exposure of infants has negative consequences on growth, otitis media, and upper and lower respiratory tract infections. Breast-feeding promoted the growth of infants who were passively exposed to tobacco smoke and protected them against infections. Smoking should not be permitted in households with infants. When this is impossible, breast-feeding should be promoted to protect the infants against the health hazards of passive smoking. [ABSTRACT FROM AUTHOR]

Published
2009
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48. Serum atrial natriuretic peptide levels in infants with transient tachypnea of the newborn.

Author

Önal, E Esra, Dİlmen, UĞur, Adam, Bahattin, TÜrkyilmaz, Canan, Uysal, FÜsun KitapÇi, and O&#011E;uz, Deniz

Subjects
*LUNG diseases, *ATRIAL natriuretic peptides, *SERUM, *BLOOD plasma, *PEPTIDES, *INFANT diseases
Abstract

Objective. The mechanisms responsible for lung liquid clearance during the neonatal period result in switching of the lung epithelium from net secretion to net absorption following birth and driven by active Na ?+? absorption. Transient tachypnea of the newborn (TTN) is known as the most common consequence of inadequate neonatal lung liquid clearance. It has been reported that alveolar type II cells behaved as a target for atrial natriuretic peptide (ANP) which inhibits the amiloride-sensitive Na-channel activity. The objective of this study is to investigate serum ANP concentrations in infants with TTN. Methods. Fourteen newborn infants who were diagnosed with TTN (gestational age; 35.6?±?2.0 weeks) and twenty healthy neonates (gestational age; 36.3?±?2.2 weeks) were included in the study. Serum pro ANP concentrations were measured by ELISA using Biomedica GmbH® (AUSTRIA) proANP kit on the 4th and 72nd hours of life. Results. The mean serum pro ANP concentration was 2996?fmol/ml at 4 and 2694?fmol/ml at 72?hours of age for the infants with TTN and mean serum pro ANP concentrations of healthy infants found 3301?fmol/ml ( p ?= 0.34) and 3204?fmol/ml ( p ?= 0.04), respectively. Conclusion. It is concluded that serum ANP concentrations decreased in infants with TTN. [ABSTRACT FROM AUTHOR]

Published
2005
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