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546 results on '"Derman, Richard"'

1. Effects of the WHO Labour Care Guide on cesarean section in India: a pragmatic, stepped-wedge, cluster-randomized pilot trial

Author

Vogel, Joshua P., Pujar, Yeshita, Vernekar, Sunil S., Armari, Elizabeth, Pingray, Veronica, Althabe, Fernando, Gibbons, Luz, Berrueta, Mabel, Somannavar, Manjunath, Ciganda, Alvaro, Rodriguez, Rocio, Bendigeri, Savitri, Kumar, Jayashree Ashok, Patil, Shruti Bhavi, Karinagannanavar, Aravind, Anteen, Raveendra R., Mallappa Ramachandrappa, Pavithra, Shetty, Shukla, Bommanal, Latha, Haralahalli Mallesh, Megha, Gaddi, Suman S., Chikkagowdra, Shaila, Raghavendra, Bellara, Homer, Caroline S. E., Lavender, Tina, Kushtagi, Pralhad, Hofmeyr, G. Justus, Derman, Richard, and Goudar, Shivaprasad

Published
2024
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2. Zinc Supplementation Initiated Prior to or During Pregnancy Modestly Impacted Maternal Status and High Prevalence of Hypozincemia in Pregnancy and Lactation: The Women First Preconception Maternal Nutrition Trial

Author

Dhaded, Sangappa M, Vernekar, Sunil S, Herekar, Veena R, Yogeshkumar, S, McClure, Elizabeth M, Das, Abhik, Thorsten, Vanessa R, Derman, Richard J, Goldenberg, Robert L, Koso-Thomas, Marion W, Kemp, Jennifer F, Hambidge, K Michael, Westcott, Jamie L, Ali, Sumera Aziz, Saleem, Sarah, Garcés, Ana, Figueroa, Lester, Somannavar, Manjunath S, Goudar, Shivaprasad S, Long, Julie M, Hendricks, Audrey E, and Krebs, Nancy F

Published
2024
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3. RAPIDIRON Trial follow-up study — the RAPIDIRON-KIDS Study: protocol of a prospective observational follow-up study

Author

Derman, Richard J., Bellad, Roopa B., Bellad, Mrutyunjaya B., Bradford-Rogers, Jesse, Georgieff, Michael K., Aghai, Zubair H., Thind, Simal, Auerbach, Michael, Boelig, Rupsa, Leiby, Benjamin E., Short, Vanessa, Yogeshkumar, S., Charantimath, Umesh S., Somannavar, Manjunath S., Mallapur, Ashalata A., Pol, Ramesh, Ramadurg, Umesh, Sangavi, Radha, Peerapur, Basavaraj V., Banu, Nasima, Patil, Praveen S., Patil, Amaresh P., Roy, Subarna, Vastrad, Phaniraj, Wallace, Dennis, Shah, Hemang, and Goudar, Shivaprasad S.

Published
2023
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4. Maternal and perinatal outcomes of women with vaginal birth after cesarean section compared to repeat cesarean birth in select South Asian and Latin American settings of the global network for women’s and children’s health research

Author

Figueroa, Lester, Harrison, Margo, Mazariegos, Manolo, Goudar, Shivaprasad, Kavi, Avinash, Derman, Richard, Patel, Archana, Das, Prabir, Hibberd, Patricia L., Saleem, Sarah, Naqvi, Farnaz, Goldenberg, Robert L., Haque, Rashidul, Billah, Sk Masum, Petri, Jr., William A., McClure, Elizabeth M., Tan, Sylvia, and Krebs, Nancy F.

Published
2023
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5. Building a predictive model of low birth weight in low- and middle-income countries: a prospective cohort study

Author

Patterson, Jackie K., Thorsten, Vanessa R., Eggleston, Barry, Nolen, Tracy, Lokangaka, Adrien, Tshefu, Antoinette, Goudar, Shivaprasad S., Derman, Richard J., Chomba, Elwyn, Carlo, Waldemar A., Mazariegos, Manolo, Krebs, Nancy F., Saleem, Sarah, Goldenberg, Robert L., Patel, Archana, Hibberd, Patricia L., Esamai, Fabian, Liechty, Edward A., Haque, Rashidul, Petri, Bill, Koso-Thomas, Marion, McClure, Elizabeth M., Bose, Carl L., and Bauserman, Melissa

Published
2023
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7. The impact of risk factors on aspirin's efficacy for the prevention of preterm birth

Author

Nuss, Emily E., Hoffman, Matthew K., Goudar, Shivaprasad S., Kavi, Avinash, Metgud, Mrityunjay, Somannavar, Manjunath, Okitawutshu, Jean, Lokangaka, Adrien, Tshefu, Antoinette, Bauserman, Melissa, Tembo, Abigail Mwapule, Chomba, Elwyn, Carlo, Waldemar A., Figueroa, Lester, Krebs, Nancy F., Jessani, Saleem, Saleem, Sarah, Goldenberg, Robert L., Kurhe, Kunal, Das, Prabir, Hibberd, Patricia L., Achieng, Emmah, Nyongesa, Paul, Esamai, Fabian, Liechty, Edward A., Bucher, Sherri, Goco, Norman, Hemingway-Foday, Jennifer, Moore, Janet, McClure, Elizabeth M., Silver, Robert M., and Derman, Richard J.

Published
2023
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8. IJCM_19A: Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: a secondary analysis of the ASPIRIN Trial

Author

Kavi Avinash, Hoffman Matthew K., Somannavar, Metgud Mrityunjay C., Goudar Shivaprasad S., Moore Janet, Nielsen Eleanor, Goco Norman, and Derman Richard J

Subjects
aspirin, hypertensive-disorders of pregnancy, nulliparous, Public aspects of medicine, RA1-1270
Abstract

Background: Hypertensive disorders of pregnancy (HDP) remain a primary contributor for maternal and perinatal death and results in long-term health risks for both the mother and child. Heterogeneous studies have evaluated the possible benefit of low dose aspirin (50 to 150 mg per day) in pregnancy to minimize the risk of HDP. Objective: To assess the impact of low-dose Aspirin (LDA) starting in early pregnancy on delaying preterm hypertensive disorders of pregnancy. Methodology: This was a non-prespecified secondary analysis of a randomized masked trial of Low-dose Aspirin (LDA). Nulliparous singleton pregnancies between 6 weeks and 0 days and 13 weeks 6 days in 6 low- middle income countries (Democratic Republic of Congo, Guatemala, India, Kenya, Pakistan, Zambia) enrolled in the ASPIRIN Trial were included. The incidence of HDP at delivery at three gestational age periods (< 37 weeks) between women who were randomized to Aspirin or Placebo. Women were included if they were randomized and had an outcome at or beyond 20 weeks (Modified Intent to Treat). Results: Amongst the 11,976 pregnancies, LDA did not significantly lower HDP at delivery. Conclusion: In low-risk nulliparous singleton pregnancies, early administration of LDA resulted in lower rates of preterm HDP and delivery before 34 and 37 weeks. LDA works in part by delaying HDP.

Published
2024
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9. Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research

Author

Patterson, Jackie K, Neuwahl, Simon, Goco, Norman, Moore, Janet, Goudar, Shivaprasad S, Derman, Richard J, Hoffman, Matthew, Metgud, Mrityunjay, Somannavar, Manjunath, Kavi, Avinash, Okitawutshu, Jean, Lokangaka, Adrien, Tshefu, Antoinette, Bose, Carl L, Mwapule, Abigail, Mwenechanya, Musaku, Chomba, Elwyn, Carlo, Waldemar A, Chicuy, Javier, Figueroa, Lester, Krebs, Nancy F, Jessani, Saleem, Saleem, Sarah, Goldenberg, Robert L, Kurhe, Kunal, Das, Prabir, Patel, Archana, Hibberd, Patricia L, Achieng, Emmah, Nyongesa, Paul, Esamai, Fabian, Bucher, Sherri, Liechty, Edward A, Bresnahan, Brian W, Koso-Thomas, Marion, and McClure, Elizabeth M

Published
2023
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10. Anthropometric and sociodemographic variables, but not preconception or prenatal maternal nutrition supplementation, predict neurodevelopment in offspring of the 'Women First' trial.

Author

Waldrop, Stephanie, Chowdhury, Dhuly, Westcott, Jamie E., Biasini, Fred, Garcés, Ana, Figueroa, Lester, Tshefu, Antoinette, Lokangaka, Adrien, Bauserman, Melissa, Saleem, Sarah, Ali, Sumera A., Goldenberg, Robert L., Goudar, Shivaprasad S., Dhaded, Sangappa M., Derman, Richard J., Kemp, Jennifer F., Koso‐Thomas, Marion, Das, Abhik, Hambidge, Michael, and Krebs, Nancy F.

Subjects
MOTOR ability, PLAY, EARLY medical intervention, RESEARCH funding, COGNITIVE testing, MATERNAL age, NEURAL development, BODY weight, LOGISTIC regression analysis, SEX distribution, QUESTIONNAIRES, MICRONUTRIENTS, CEPHALOMETRY, DESCRIPTIVE statistics, STATURE, PRECONCEPTION care, CHILD development, PSYCHOLOGY of mothers, FETAL development, ANTHROPOMETRY, SOCIODEMOGRAPHIC factors, CONFIDENCE intervals, DATA analysis software, BIRTH weight, DIETARY supplements, DIET therapy, SOCIAL classes, SENSITIVITY & specificity (Statistics), EDUCATIONAL attainment, CHILDREN
Abstract

Multiple factors influence infant and child neurodevelopment in low resource settings. In offspring of participants in the preconception maternal nutrition trial, Women First (WF), we examined the impact of providing a preconception (Arm 1) or prenatal (Arm 2) nutrient supplement (compared to controls, Arm 3) on neurodevelopmental outcomes at 24 months; predictors of neurodevelopment scores; and associations of infant anthropometrics with neurodevelopmental scores. Follow‐up visits for anthropometry were conducted at 6‐, 12‐, 18‐ and 24‐month of age. At 24‐months, in a randomized subset, the Bayley Scales of Infant Development, 3rd edition (BSID‐III), including cognitive, motor and social‐emotional subscales, and the Family Care Indicators (FCI) questionnaire, assessing family and home environment, were completed. Multiple covariates (intervention arm, site, maternal sociodemographic characteristics, FCI subscales, birthweight and 6–24 months' change in anthropometry z‐scores, (e.g., ΔLAZ6–24) were evaluated by linear regression to predict BSID‐III outcomes and to assess associations of anthropometric changes with BSID‐III scores. The analysis consisted of 1386 infants (n = 441, 486, 459 for Arms 1, 2 and 3, respectively). None of the domain‐specific BSID‐III subscale scores differed by maternal intervention arm. Four covariates significantly predicted (p ≤ 0.01) all 3 BSID‐III subscales: secondary maternal education, ΔLAZ6–24, birthweight >2500 g, and FCI play materials. Linear growth was associated with all domains of neurodevelopment. The results underscore the multi‐dimensional aspects of child development represented by the nurturing care framework, including prenatal maternal nutrition, post‐natal growth, maternal education for responsive caregiving and opportunities for early learning. Key messages: Preconception and prenatal maternal nutrition is important to ensure adequate fetal growth and healthy birthweight.Preconception and prenatal maternal nutritional supplementation was not associated with young child neurodevelopment but has been shown to improve post‐natal growth.Post‐natal linear growth is consistently associated with offspring neurodevelopment at 24 months.Maternal education to foster responsive caregiving, and opportunities for early learning in the home also positively impact offspring neurodevelopmental outcomes.These findings underscore the importance of multi‐dimensional aspects essential for children to reach their full developmental potential. [ABSTRACT FROM AUTHOR]

Published
2024
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13. The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries

Author

Bauserman, Melissa, Leuba, Sequoia I., Hemingway-Foday, Jennifer, Nolen, Tracy L., Moore, Janet, McClure, Elizabeth M., Lokangaka, Adrien, Tsehfu, Antoinette, Patterson, Jackie, Liechty, Edward A., Esamai, Fabian, Carlo, Waldemar A., Chomba, Elwyn, Goldenberg, Robert L., Saleem, Sarah, Jessani, Saleem, Koso-Thomas, Marion, Hoffman, Matthew, Derman, Richard J., Meshnick, Steven R., and Bose, Carl L.

Published
2022
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14. Causes and circumstances of maternal death: a secondary analysis of the Community-Level Interventions for Pre-eclampsia (CLIP) trials cohort

Author

Woo Kinshella, Mai-Lei, Wong, Hubert, von Dadelszen, Peter, Vilanculo, Faustino, Vidler, Marianne, Valá, Anifa, Ukah, Ugochi V, Tu, Domena K, Thabane, Lehana, Tchavana, Corsino, Thornton, Jim, Sotunsa, John O, Singer, Joel, Sheikh, Sana, Sharma, Sumedha, Sevene, Esperança, Schuurman, Nadine, Sawchuck, Diane, Sacoor, Charfudin, Revankar, Amit P, Raza, Farrukh, Ramdurg, Umesh Y, Qureshi, Rahat N, Pires, Rosa, Payne, Beth A, Nobela, Vivalde, Nkumbula, Cláudio, Nhancolo, Ariel, Nhamirre, Zefanias, Munguambe, Khátia, Mungarwadi, Geetanjali I, Mulungo, Dulce, Mocumbi, Sibone, Mitton, Craig, Merialdi, Mario, Memon, Javed, Matavele, Analisa, Mastiholi, Sphoorthi S, Mandlate, Ernesto, Mallapur, Ashalata A, Magee, Laura A, Maculuve, Sónia, Macuacua, Salésio, Macete, Eusébio, Macamo, Marta, Lui, Mansun, Li, Jing, Lewis, Gwyneth, Lewin, Simon, Lee, Tang, Langer, Ana, Kudachi, Uday S, Kodkany, Bhalachandra S, Knight, Marian, Kengapur, Gudadayya S, Kavi, Avinash J, Katageri, Geetanjali, Kariya, Chirag, Karadiguddi, Chandrappa C, Kamble, Namdev A, Joshi, Anjali M, Hutton, Eileen, Hussain, Amjad, Honnungar, Narayan V, Hoodbhoy, Zahra, Grobman, William, Goudar, Shivaprasad S, Gonçálves, Emília, Firoz, Tabassum, Fillipi, Veronique, Filimone, Paulo, Engelbrecht, Susheela M, Dunsmuir, Dustin T, Dumont, Guy, Drebit, Sharla K, Donnay, France, Dharamsi, Shafik, Dhamanekar, Vaibhav B, Derman, Richard, Darlow, Brian, Cutana, Silvestre, Chougala, Keval S, Chiaú, Rogério, Charantimath, Umesh, Byaruhanga, Romano Nkumbwa, Bone, Jeffrey N, Boene, Helena, Biz, Ana Ilda, Bique, Cassimo, Bhutta, Zulfiqar A, Betrán, Ana Pilar, Bellad, Mrutyunjaya B, Bannale, Shashidhar G, Aukes, Annet M, Augusto, Orvalho, Arion, Kristina, Ansermino, J Mark, Amose, Felizarda, Ahmed, Imran, and Adetoro, Olalekan O

Published
2021
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15. Blood pressure thresholds in pregnancy for identifying maternal and infant risk: a secondary analysis of Community-Level Interventions for Pre-eclampsia (CLIP) trial data

Author

Woo Kinshella, Mai-Lei, Wong, Hubert, Vilanculo, Faustino, Vala, Anifa, Ukah, Ugochi V, Tu, Domena K, Thabane, Lehana, Tchavana, Corsino, Thornton, Jim, Sotunsa, John O, Sheikh, Sana, Sharma, Sumedha, Schuurman, Nadine, Sawchuck, Diane, Revankar, Amit P, Raza, Farrukh, Ramdurg, Umesh Y, Pires, Rosa, Payne, Beth A, Nobela, Vivalde, Nkumbula, Cláudio, Nhancolo, Ariel, Nhamirre, Zefanias, Mungarwadi, Geetanjali I, Mulungo, Dulce, Mocumbi, Sibone, Mitton, Craig, Merialdi, Mario, Memon, Javed, Matavele, Analisa, Mastiholi, Sphoorthi S, Mandlate, Ernesto, Maculuve, Sónia, Macuacua, Salésio, Macete, Eusébio, Macamo, Marta, Lui, Mansun, Li, Jing, Lewis, Gwyneth, Lewin, Simon, Lee, Tang, Langer, Ana, Kudachi, Uday S, Kodkany, Bhalachandra S, Knight, Marian, Kengapur, Gudadayya S, Kavi, Avinash J, Katageri, Geetanjali M, Kariya, Chirag, Karadiguddi, Chandrappa C, Kamble, Namdev A, Joshi, Anjali M, Hutton, Eileen, Hussain, Amjad, Hoodbhoy, Zahra, Honnungar, Narayan V, Grobman, William, Gonçálves, Emília, Firoz, Tabassum, Fillipi, Veronique, Filimone, Paulo, Engelbrecht, Susheela M, Dunsmuir, Dustin T, Dumont, Guy, Drebit, Sharla K, Donnay, France, Dharamsi, Shafik, Dhamanekar, Vaibhav B, Derman, Richard, Darlow, Brian, Cutana, Silvestre, Chougala, Keval S, Chiaú, Rogério, Charantimath, Umesh S, Byaruhanga, Romano Nkumbwa, Boene, Helena, Biz, Ana Ilda, Bique, Cassimo, Betrán, Ana Pilar, Bannale, Shashidhar G, Augusto, Orvalho, Ansermino, J Mark, Amose, Felizarda, Ahmed, Imran, Adetoro, Olalekan O, Bone, Jeffrey N, Magee, Laura A, Singer, Joel, Nathan, Hannah, Qureshi, Rahat N, Sacoor, Charfudin, Sevene, Esperança, Shennan, Andrew, Bellad, Mrutyunjaya B, Goudar, Shivaprasad S, Mallapur, Ashalata A, Munguambe, Khátia, Vidler, Marianne, Bhutta, Zulfiqar A, and von Dadelszen, Peter

Published
2021
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16. Intrapartum and postpartum antibiotic use in seven low‐ and middle‐income countries: Findings from the A‐PLUS trial.

Author

Saleem, Sarah, Yasmin, Haleema, Moore, Janet L., Rahim, Anum, Shakeel, Iram, Lokangaka, Adrien, Tshefu, Antoinette, Bauserman, Melissa, Mwenechanya, Musaku, Chomba, Elwyn, Goudar, Shivaprasad S., Kavi, Avinash, Derman, Richard J., Krebs, Nancy F., Figueroa, Lester, Mazariegos, Manolo, Nyongesa, Paul, Bucher, Sherri, Esamai, Fabian, and Patel, Archana

Abstract

Objective: To describe the intrapartum and postpartum use of non‐study antibiotics in low‐ and middle‐income countries (LMICs) during the double‐blinded NICHD Global Network Azithromycin in Labor (A‐PLUS) trial. Design: The antibiotic use sub‐study was a planned prospective, observational sub‐study of the A‐PLUS trial. Settings: The study was carried out in hospitals or health centres affiliated with eight sites of the Global Network for Women's and Children's Health Research (Global Network) in seven countries: Bangladesh, Pakistan, India (two sites), Kenya, Zambia, The Democratic Republic of the Congo (DRC) and Guatemala. Population: Totally, 29 278 pregnant women enrolled in the A‐PLUS trial. Methods: We collected data on 29 278 pregnant women admitted to a facility for delivery related to non‐study antibiotic use overall and during three time periods: (1) in the facility prior to delivery, (2) after delivery until facility discharge and (3) after discharge to 42 days post‐partum. Main Outcome Measures: Non‐study antibiotic use overall and for treatment or prophylaxis by the site during the three time periods. Results: Of the 29 278 women in the study, 5020 (17.1%; 95% CI 16.7%–17.6%) received non‐study antibiotics in the facility prior to delivery, 11 956 (40.8%; 95% CI 40.3%–41.4%) received non‐study antibiotics in the facility after delivery, and 13 390 (47.6%; 95% CI 47.0%–48.2%) women received non‐study antibiotics after delivery and after facility discharge. Antibiotics were prescribed more often among women in the Asian and Guatemalan sites than in the African sites. In the three time‐periods, among those receiving antibiotics, prophylaxis was the indication in 82.3%, 97.7% and 90.7% of the cases, respectively. The type of antibiotics used varied substantially by time‐period and site, but generally, penicillin‐type drugs, cephalosporin‐type drugs and metronidazole were used more frequently than other types. Conclusions: Across the eight sites of the Global Network, in the facility before delivery, and in the post‐partum periods before and after facility discharge, antibiotics were used frequently, but use was highly variable by site and time‐period. [ABSTRACT FROM AUTHOR]

Published
2025
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17. Growth from Birth Through Six Months for Infants of Mothers in the “Women First” Preconception Maternal Nutrition Trial

Author

Gado, Justin, Somannavar, Manjunath S., Herekar, Veena, Pasha, Omrana, Khan, Umber, McClure, Elizabeth M., Koso-Thomas, Marion, Krebs, Nancy F., Hambidge, K. Michael, Westcott, Jamie L., Garcés, Ana L., Figueroa, Lester, Tsefu, Antoinette K., Lokangaka, Adrien L., Goudar, Shivaprasad S., Dhaded, Sangappa M., Saleem, Sarah, Ali, Sumera Aziz, Bose, Carl L., Derman, Richard J., Goldenberg, Robert L., Thorsten, Vanessa R., Sridhar, Amaanti, Chowdhury, Dhuly, and Das, Abhik

Published
2021
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18. Antibiotic use in infants in the 6 weeks after delivery in seven low- and middle-income countries: findings from the A-PLUS trial.

Author

Yasmin, Haleema, Tanveer, Saba, Sunder Tikmani, Shiyam, Moore, Janet L., Shakeel, Iram, Rahim, Anum, Lokangaka, Adrien, Tshefu, Antoinette, Bauserman, Melissa, Mwenechanya, Musaku, Chomba, Elwyn, Goudar, Shivaprasad S., Kavi, Avinash, Derman, Richard J., Krebs, Nancy F., Figueroa, Lester, Mazariegos, Manolo, Nyongesa, Paul, Bucher, Sherri, and Esamai, Fabian

Subjects
DELIVERY (Obstetrics), PREMATURE infants, MIDDLE-income countries, HOSPITAL admission & discharge, DRUG resistance in microorganisms
Abstract

Objectives: Antibiotic use is increasing in low- and middle-income countries (LMIC); however, few studies have examined the rates of use in a population. The use of antibiotics for liveborn infants in LMIC was examined. Design: The study, a planned prospective, observational secondary analysis of the A-PLUS randomised controlled trial of azithromycin, was conducted in Global Network sites in seven countries: Bangladesh, Pakistan, India (two sites), Kenya, Zambia, the Democratic Republic of Congo and Guatemala. The analyses included liveborn infants of women planning a vaginal delivery who were enrolled in the A-PLUS trial. Methods: Data were collected on liveborn infants related to non-study antibiotic use in two time-periods: (i) after delivery while in the facility, and (ii) after discharge until 42 days post-partum. Antibiotic use was also examined in preterm and term infants. The most commonly used antibiotics were classified into three groups: penicillins, cephalosporins and aminoglycosides. Antibiotics used in <1% of infants are not presented. Results: Of the 29,354 eligible infants in the study, 2224 (7.6%, 95% CI 7.3–7.9) received non-study antibiotics in the facility after delivery, and 3847 (13.1%, 95% CI 12.7–13.5) received non-study antibiotics after facility discharge until Day 42. In the facility, antibiotics were given to newborns more frequently in sites in Asia and less frequently in sites in Africa and Guatemala. Similarly, after facility discharge, infants were more likely to receive antibiotics in the Asian sites and less so in the African sites and Guatemala. In the facilities, antibiotics were used predominately for prophylaxis (70.7%) but after facility discharge antibiotics were given more often for treatment (56.8%). Preterm infants received more non-study antibiotics than term infants. The antibiotics used varied substantially by time-period and site but, in general, penicillins, cephalosporins and aminoglycosides were the antibiotic categories used more frequently. Conclusions: Across the Global Network sites, which represent a range of LMIC, nearly 8% of infants received non-study antibiotics more often for prophylaxis, with 13% of infants receiving non-study antibiotics following hospital discharge. With concerns about increasing antimicrobial resistance worldwide, further attention should be given to appropriate antibiotic use. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Community level interventions for pre-eclampsia (CLIP) in India: A cluster randomised controlled trial

Author

Bellad, Mrutunjaya B., Goudar, Shivaprasad S., Mallapur, Ashalata A., Sharma, Sumedha, Bone, Jeffrey, Charantimath, Umesh S., Katageri, Geetanjali M., Ramadurg, Umesh Y, Mark Ansermino, J., Derman, Richard J., Dunsmuir, Dustin T., Honnungar, Narayan V., Karadiguddi, Chandrashekhar, Kavi, Avinash J., Kodkany, Bhalachandra S., Lee, Tang, Li, Jing, Nathan, Hannah L., Payne, Beth A., Revankar, Amit P., Shennan, Andrew H., Singer, Joel, Tu, Domena K., Vidler, Marianne, Wong, Hubert, Bhutta, Zulfiqar A., Magee, Laura A., and von Dadelszen, Peter

Published
2020
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21. Safety and efficacy of the new CryoPop® cryotherapy device for cervical dysplasia in low- and middle-income countries: study protocol for a multicenter open-label non-inferiority clinical trial with historical controls

Author

Yogeshkumar, S., Anderson, Jean, Lu, Enriquito, Kenyi, Edward, Mensa, Margaret, Thaler, Katrina, Antartani, Ramalingappa, Donimath, Kasturi, Patil, Basavaraj, Chikaraddi, Santosh, Bidri, Shailaja, Biradar, Aruna, Gudadinni, Muttappa R., Lokare, Laxmikant, Yenokyan, Gayane, Bellad, Mrutyunjaya B., Goudar, Shivaprasad S., Derman, Richard, Revankar, Amit, Patil, Hema, Wani, Ramadevi, Kangle, Ranjit, Chavan, Ramesh Y., Nagmoti, Mahantesh B., Kabadi, Yogendra M., Reddy, Purushotham, Vernekar, Sunita, Hipparagi, Surekha, Patil, Vijayalaxmi, and Dalal, Anita

Published
2021
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22. A multicountry randomized controlled trial of comprehensive maternal nutrition supplementation initiated before conception: the Women First trial

Author

Hambidge, K Michael, Westcott, Jamie E, Garcés, Ana, Figueroa, Lester, Goudar, Shivaprasad S, Dhaded, Sangappa M, Pasha, Omrana, Ali, Sumera A, Tshefu, Antoinette, Lokangaka, Adrien, Derman, Richard J, Goldenberg, Robert L, Bose, Carl L, Bauserman, Melissa, Koso-Thomas, Marion, Thorsten, Vanessa R, Sridhar, Amaanti, Stolka, Kristen, Das, Abhik, McClure, Elizabeth M, and Krebs, Nancy F

Published
2019
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23. An approach to identify a minimum and rational proportion of caesarean sections in resource-poor settings: a global network study

Author

Belizán, José M, Minckas, Nicole, McClure, Elizabeth M, Saleem, Sarah, Moore, Janet L, Goudar, Shivaprasad S, Esamai, Fabian, Patel, Archana, Chomba, Elwyn, Garces, Ana L, Althabe, Fernando, Harrison, Margo S, Krebs, Nancy F, Derman, Richard J, Carlo, Waldemar A, Liechty, Edward A, Hibberd, Patricia L, Buekens, Pierre M, and Goldenberg, Robert L

Published
2018
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24. Corrigendum to The impact of risk factors on aspirin's efficacy for the prevention of preterm birth. American Journal of Obstetrics & Gynecology MFM. Volume 5, Issue 10, October 2023, 101095

Author

Nuss, Emily E., Hoffman, Matthew K., Goudar, Shivaprasad S., Kavi, Avinash, Metgud, Mrityunjay, Somannavar, Manjunath, Okitawutshu, Jean, Lokangaka, Adrien, Tshefu, Antoinette, Bauserman, Melissa, Tembo, Abigail Mwapule, Chomba, Elwyn, Carlo, Waldemar A., Figueroa, Lester, Krebs, Nancy F., Jessani, Saleem, Saleem, Sarah, Goldenberg, Robert L., Kurhe, Kunal, Das, Prabir, Hibberd, Patricia L., Achieng, Emmah, Nyongesa, Paul, Esamai, Fabian, Liechty, Edward A., Bucher, Sherri, Goco, Norman, Hemingway-Foday, Jennifer, Moore, Janet, McClure, Elizabeth M., Silver, Robert M., Derman, Richard J., and Patel, Archana

Published
2024
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26. Institutional deliveries and stillbirth and neonatal mortality in the Global Network's Maternal and Newborn Health Registry

Author

Goudar, Shivaprasad S., Goco, Norman, Somannavar, Manjunath S., Kavi, Avinash, Vernekar, Sunil S., Tshefu, Antoinette, Chomba, Elwyn, Garces, Ana L., Saleem, Sarah, Naqvi, Farnaz, Patel, Archana, Esamai, Fabian, Bose, Carl L., Carlo, Waldemar A., Krebs, Nancy F., Hibberd, Patricia L., Liechty, Edward A., Koso-Thomas, Marion, Nolen, Tracy L., Moore, Janet, Iyer, Pooja, McClure, Elizabeth M., Goldenberg, Robert L., and Derman, Richard J.

Published
2020
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27. Cesarean birth in the Global Network for Women’s and Children’s Health Research: trends in utilization, risk factors, and subgroups with high cesarean birth rates

Author

Harrison, Margo S., Garces, Ana L., Goudar, Shivaprasad S., Saleem, Sarah, Moore, Janet L., Esamai, Fabian, Patel, Archana B., Chomba, Elwyn, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Hibberd, Patricia L., Carlo, Waldemar A., Tshefu, Antoinette, Koso-Thomas, Marion, McClure, Elizabeth M., and Goldenberg, Robert L.

Published
2020
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28. Association of parity with birthweight and neonatal death in five sites: The Global Network’s Maternal Newborn Health Registry study

Author

Garces, Ana, Perez, Wilton, Harrison, Margo S., Hwang, Kay S., Nolen, Tracy L., Goldenberg, Robert L., Patel, Archana B., Hibberd, Patricia L., Lokangaka, Adrien, Tshefu, Antoinette, Saleem, Sarah, Goudar, Shivaprasad S., Derman, Richard J., Patterson, Jacquelyn, Koso-Thomas, Marion, McClure, Elizabeth M., Krebs, Nancy F., and Hambidge, K. Michael

Published
2020
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29. Why are the Pakistani maternal, fetal and newborn outcomes so poor compared to other low and middle-income countries?

Author

Aziz, Aleha, Saleem, Sarah, Nolen, Tracy L., Pradhan, Nousheen Akber, McClure, Elizabeth M., Jessani, Saleem, Garces, Ana L., Hibberd, Patricia L., Moore, Janet L., Goudar, Shivaprasad S., Dhaded, Sangappa M., Esamai, Fabian, Tenge, Constance, Patel, Archana B., Chomba, Elwyn, Mwenechanya, Musaku, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Tshefu, Antoinette, Koso-Thomas, Marion, Siddiqi, Sameen, and Goldenberg, Robert L.

Published
2020
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30. Maternal mortality in six low and lower-middle income countries from 2010 to 2018: risk factors and trends

Author

Bauserman, Melissa, Thorsten, Vanessa R., Nolen, Tracy L., Patterson, Jackie, Lokangaka, Adrien, Tshefu, Antoinette, Patel, Archana B., Hibberd, Patricia L., Garces, Ana L., Figueroa, Lester, Krebs, Nancy F., Esamai, Fabian, Nyongesa, Paul, Liechty, Edward A., Carlo, Waldemar A., Chomba, Elwyn, Goudar, Shivaprasad S., Kavi, Avinash, Derman, Richard J., Saleem, Sarah, Jessani, Saleem, Billah, Sk Masum, Koso-Thomas, Marion, McClure, Elizabeth M., Goldenberg, Robert L., and Bose, Carl

Published
2020
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31. Regional trends in birth weight in low- and middle-income countries 2013–2018

Author

Marete, Irene, Ekhaguere, Osayame, Bann, Carla M., Bucher, Sherri L., Nyongesa, Paul, Patel, Archana B., Hibberd, Patricia L., Saleem, Sarah, Goldenberg, Robert L., Goudar, Shivaprasad S., Derman, Richard J., Garces, Ana L., Krebs, Nancy F., Chomba, Elwyn, Carlo, Waldemar A., Lokangaka, Adrien, Bauserman, Melissa, Koso-Thomas, Marion, Moore, Janet L., McClure, Elizabeth M., and Esamai, Fabian

Published
2020
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32. Development of the Global Network for Women’s and Children’s Health Research’s socioeconomic status index for use in the network’s sites in low and lower middle-income countries

Author

Patel, Archana B., Bann, Carla M., Garces, Ana L., Krebs, Nancy F., Lokangaka, Adrien, Tshefu, Antoinette, Bose, Carl L., Saleem, Sarah, Goldenberg, Robert L., Goudar, Shivaprasad S., Derman, Richard J., Chomba, Elwyn, Carlo, Waldemar A., Esamai, Fabian, Liechty, Edward A., Koso-Thomas, Marion, McClure, Elizabeth M., and Hibberd, Patricia L.

Published
2020
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33. Rates and risk factors for preterm birth and low birthweight in the global network sites in six low- and low middle-income countries

Author

Pusdekar, Yamini V., Patel, Archana B., Kurhe, Kunal G., Bhargav, Savita R., Thorsten, Vanessa, Garces, Ana, Goldenberg, Robert L., Goudar, Shivaprasad S., Saleem, Sarah, Esamai, Fabian, Chomba, Elwyn, Bauserman, Melissa, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Koso-Thomas, Marion, Nolen, Tracy L., McClure, Elizabeth M., and Hibberd, Patricia L.

Published
2020
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35. Evaluating the effect of care around labor and delivery practices on early neonatal mortality in the Global Network’s Maternal and Newborn Health Registry

Author

Patel, Archana B., Simmons, Elizabeth M., Rao, Sowmya R., Moore, Janet, Nolen, Tracy L., Goldenberg, Robert L., Goudar, Shivaprasad S., Somannavar, Manjunath S., Esamai, Fabian, Nyongesa, Paul, Garces, Ana L., Chomba, Elwyn, Mwenechanya, Musaku, Saleem, Sarah, Naqvi, Farnaz, Bauserman, Melissa, Bucher, Sherri, Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Koso-ThomasMcClure, Marion Elizabeth M., and Hibberd, Patricia L.

Published
2020
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36. The relationship between birth intervals and adverse maternal and neonatal outcomes in six low and lower-middle income countries

Author

Bauserman, Melissa, Nowak, Kayla, Nolen, Tracy L., Patterson, Jackie, Lokangaka, Adrien, Tshefu, Antoinette, Patel, Archana B., Hibberd, Patricia L., Garces, Ana L., Figueroa, Lester, Krebs, Nancy F., Esamai, Fabian, Liechty, Edward A., Carlo, Waldemar A., Chomba, Elwyn, Mwenechanya, Musaku, Goudar, Shivaprasad S., Ramadurg, Umesh, Derman, Richard J., Saleem, Sarah, Jessani, Saleem, Koso-Thomas, Marion, McClure, Elizabeth M., Goldenberg, Robert L., and Bose, Carl

Published
2020
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37. Stillbirth 2010–2018: a prospective, population-based, multi-country study from the Global Network

Author

McClure, Elizabeth M., Saleem, Sarah, Goudar, Shivaprasad S., Garces, Ana, Whitworth, Ryan, Esamai, Fabian, Patel, Archana B., Tikmani, Shiyam Sunder, Mwenechanya, Musaku, Chomba, Elwyn, Lokangaka, Adrien, Bose, Carl L., Bucher, Sherri, Liechty, Edward A., Krebs, Nancy F., Yogesh Kumar, S., Derman, Richard J., Hibberd, Patricia L., Carlo, Waldemar A., Moore, Janet L., Nolen, Tracy L., Koso-Thomas, Marion, and Goldenberg, Robert L.

Published
2020
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39. Neonatal deaths in infants born weighing ≥ 2500 g in low and middle-income countries

Author

Saleem, Sarah, Naqvi, Farnaz, McClure, Elizabeth M., Nowak, Kayla J., Tikmani, Shiyam Sunder, Garces, Ana L., Hibberd, Patricia L., Moore, Janet L., Nolen, Tracy L., Goudar, Shivaprasad S., Kumar, Yogesh, Esamai, Fabian, Marete, Irene, Patel, Archana B., Chomba, Elwyn, Mwenechanya, Musaku, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Tshefu, Antoinette, Koso-Thomas, Marion, Siddiqi, Sameen, and Goldenberg, Robert L.

Published
2020
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40. The Global Network Maternal Newborn Health Registry: a multi-country, community-based registry of pregnancy outcomes

Author

McClure, Elizabeth M., Garces, Ana L., Hibberd, Patricia L., Moore, Janet L., Goudar, Shivaprasad S., Saleem, Sarah, Esamai, Fabian, Patel, Archana, Chomba, Elwyn, Lokangaka, Adrien, Tshefu, Antoinette, Haque, Rashidul, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Petri, William, Koso-Thomas, Marion, and Goldenberg, Robert L.

Published
2020
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42. Looking beyond the numbers: quality assurance procedures in the Global Network for Women’s and Children’s Health Research Maternal Newborn Health Registry

Author

Garces, Ana, MacGuire, Emily, Franklin, Holly L., Alfaro, Norma, Arroyo, Gustavo, Figueroa, Lester, Goudar, Shivaprasad S., Saleem, Sarah, Esamai, Fabian, Patel, Archana, Chomba, Elwyn, Tshefu, Antoinette, Haque, Rashidul, Patterson, Jacquelyn K., Liechty, Edward A., Derman, Richard J., Carlo, Waldemar A., Petri, William, Koso-ThomasMcClure, Marion Elizabeth M., Goldenberg, Robert L., Hibberd, Patricia, and Krebs, Nancy F.

Published
2020
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43. Is It Time to Alter the Standard of Care for Iron Deficiency/Iron Deficiency Anemia in Reproductive-Age Women?

Author

Bellad, Mrutyunjaya B., Patted, Anmol, and Derman, Richard J.

Subjects
IRON deficiency anemia, IRON deficiency, IRON supplements, UNITS of time, PHYSICAL mobility
Abstract

Two billion people worldwide suffer from anemia, with reproductive-age women being disproportionately affected. Iron plays a crucial role in cellular function and impacts cognition, physical function, and quality of life. Iron deficiency (ID) and iron deficiency anemia (IDA) are associated with adverse effects on pregnancy and fetal development. Oral iron supplementation has been the standard treatment for decades, often producing sub-optimal outcomes. Many babies are still being born with ID and suffer adverse sequelae due to inadequate iron levels in the mothers. Is it time to consider a broad scale-up of parenteral iron as a new standard of care? [ABSTRACT FROM AUTHOR]

Published
2024
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44. Neonatal Respiratory Support Utilization in Low- and Middle-Income Countries: A Registry-Based Observational Study.

Author

Switchenko, Nora, Shukla, Vivek, Mwenechanya, Musaku, Chomba, Elwyn, Patel, Archana, Hibberd, Patricia L., Ambalavanan, Namasivayam, Figueroa, Lester, Mazariegos, Manolo, Krebs, Nancy F., Goudar, Shivaprasad S., Derman, Richard, Esamai, Fabian, Liechty, Edward A., Bucher, Sheri, Saleem, Sarah, Goldenberg, Robert L., Lokangaka, Adrien, Tshefu, Antoinette, and Bose, Carl L.

Subjects
MIDDLE-income countries, PREMATURE infants, BIRTH weight, RESOURCE-limited settings, LOW birth weight
Abstract

Background: Newborns with hypoxemia often require life-saving respiratory support. In low-resource settings, it is unknown if respiratory support is delivered more frequently to term infants or preterm infants. We hypothesized that in a registry-based birth cohort in 105 geographic areas in seven low- and middle-income countries, more term newborns received respiratory support than preterm newborns. Methods: This is a hypothesis-driven observational study based on prospectively collected data from the Maternal and Newborn Health Registry of the NICHD Global Network for Women's and Children's Health Research. Eligible infants enrolled in the registry were live-born between 22 and 44 weeks gestation with a birth weight ≥400 g and born from January 1, 2015, to December 31, 2018. Frequency data were obtained to report the number of term and preterm infants who received treatment with oxygen only, CPAP, or mechanical ventilation. Test for trends over time were conducted using robust Poisson regression. Results: 177,728 (86.3%) infants included in this study were term, and 28,249 (13.7%) were preterm. A larger number of term infants (n = 5,108) received respiratory support compared to preterm infants (n = 3,287). Receipt of each mode of respiratory support was more frequent in term infants. The proportion of preterm infants who received respiratory support (11.6%) was higher than the proportion of term infants receiving respiratory support (2.9%, p < 0.001). The rate of provision of respiratory support varied between sites. Conclusions: Respiratory support was more frequently used in term infants expected to be at low risk for respiratory disorders compared to preterm infants. [ABSTRACT FROM AUTHOR]

Published
2024
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45. Low-Dose Aspirin for the Prevention of Preterm Delivery in Nulliparous Women With a Singleton Pregnancy (ASPIRIN): A Randomized, Double-blind, Placebo-Controlled Trial

Author

Hoffman, Matthew K., Goudar, Shivaprasad S., Kodkany, Bhalachandra S., Metgud, Mrityunjay, Somannavar, Manjunath, Okitawutshu, Jean, Lokangaka, Adrien, Tshefu, Antoinette, Bose, Carl L., Mwapule, Abigail, Mwenechanya, Musaku, Chomba, Elwyn, Carlo, Waldemar A., Chicuy, Javier, Figueroa, Lester, Garces, Ana, Krebs, Nancy F., Jessani, Saleem, Zehra, Farnaz, Saleem, Sarah, Goldenberg, Robert L., Kurhe, Kunal, Das, Prabir, Patel, Archana, Hibberd, Patricia L., Achieng, Emmah, Nyongesa, Paul, Esamai, Fabian, Liechty, Edward A., Goco, Norman, Hemingway-Foday, Jennifer, Moore, Janet, Nolen, Tracy L., McClure, Elizabeth M., Koso-Thomas, Marion, Miodovnik, Menachem, Silver, R., and Derman, Richard J.

Published
2020
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46. Prevalence of chronic disease in older adults in multitier eye-care facilities in South India: Electronic medical records-driven big data analytics report

Author

Behera, Umesh, Salzman, Brooke, Das, Anthony, Prashanthi, Gumpili, Lalakia, Parth, Derman, Richard, and Panigrahy, Bharat

Subjects
Aged patients -- Statistics, Eye diseases -- Statistics -- Risk factors -- Demographic aspects, Chronic diseases -- Statistics -- Risk factors -- Demographic aspects, Health
Abstract

Byline: Umesh. Behera, Brooke. Salzman, Anthony. Das, Gumpili. Prashanthi, Parth. Lalakia, Richard. Derman, Bharat. Panigrahy Purpose: To study the prevalence of systemic conditions in older adults, either self-reported or discovered [...]

Published
2021

47. The CryoPop study: Screening for high‐grade cervical dysplasia in Karnataka, India.

Author

Anderson, Jean R., Yogeshkumar, S., Lu, Enriquito, Yenokyan, Gayane, Thaler, Katrina, Mensa, Margaret, Chikaraddi, Santosh, Lokare, Laxmikant, Gudadinni, Muttappa R., Antartani, Ramalingappa, Donimath, Kasturi, Patil, Basavaraj, Bidri, Shailaja, Goudar, Shivaprasad S., Derman, Richard, Dalal, Anita, Bellad, Mrutyunjaya Basavanneppa, Patil, Hema S., Wani, Ramadevi, and Ranjit, Kangle

Subjects
COLPOSCOPY, COLD therapy, MEDICAL screening, CERVICAL intraepithelial neoplasia, INCOME, EARLY detection of cancer, FISHER exact test
Abstract

Objective: To describe our experience of screening with visual inspection with acetic acid (VIA) and colposcopy to identify women with high‐grade precancerous cervical lesions who were candidates for cryotherapy. Women were screened to determine eligibility for a clinical trial testing the safety and efficacy of a new, simple and inexpensive cryotherapy device (CryoPop®) targeted for use in low and middle‐income countries (LMICs). Design: Prospective cohort study. Setting: Primary and urban health centres in Belagavi, Hubballi and Vijayapur, India. Population: Women in the age‐group 30–49 years, premenopausal, with no prior hysterectomy and no known HIV infection were eligible for screening. Methods: Visual inspection with acetic acid was performed on eligible women following informed consent. VIA‐positive women were referred for colposcopy and biopsy. Biopsies were read by two pathologists independently, with a third pathologist acting as tie‐breaker if needed. Main outcome measures: The primary outcome measures were the number/proportion of women screening positive by VIA and the number/proportion of those women screening VIA‐positive found to have high‐grade cervical lesions on biopsy (cervical intraepithelial neoplasia 2/3 [CIN 2/3]). Demographic variables were compared between women who screened VIA‐positive and those who screened VIA‐negative; a separate comparison of demographic and limited reproductive variables was performed between women who had CIN 2/3 on biopsy and those without CIN 2/3 on biopsy. Chi‐square or Fisher's exact tests for categorical data and t‐tests or analysis of variance for numeric data were used with all tests two‐sided and performed at an alpha 0.05 level of statistical significance. Results: A total of 9130 women were screened with VIA between 4 July 2020 and 31 March 2021. The mean age of all women screened was 37 years (standard deviation = 5.6 years) with 6073 of the women (66.5%) in the 30–39 year range. Only 1% of women reported prior cervical cancer screening. A total of 501 women (5.5%) were VIA‐positive; of these, 401 women underwent colposcopy. Of those who had colposcopy, 17 (4.2%) had high‐grade lesions on biopsy, an additional 164 (40.9%) had low‐grade cervical lesions on biopsy or endocervical curettage and one woman (0.2%) was found to have invasive cancer. VIA‐positive women were younger and had higher levels of education and income; however, women who were VIA‐positive and found to have CIN 2/3 were older, were more likely to be housewives and had higher household income than those without CIN 2/3. Conclusion: Despite the COVID‐19 pandemic, over 9100 women were screened with VIA for precancerous lesions. However, only 17 (4.2%) were found to have biopsy‐proven high‐grade cervical lesions, underscoring the subjective performance of VIA as a screening method. Given that this is significantly lower than rates reported in the literature, it is possible that the prevalence of high‐grade lesions in this population was impacted by screening a younger and more rural population. This study demonstrates that screening is feasible in an organised fashion and can be scaled up rapidly. However, while inexpensive and allowing for same‐day treatment, VIA may be too subjective and have insufficient accuracy clearly to identify lesions requiring treatment, particularly in low‐prevalence and low‐risk populations, calling into question its overall cost‐effectiveness. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Trends over time in the knowledge, attitude and practices of pregnant women related to COVID‐19: A cross‐sectional survey from seven low‐ and middle‐income countries.

Author

Jessani, Saleem, Saleem, Sarah, Fogleman, Elizabeth, Billah, Sk Masum, Haque, Rashidul, Figueroa, Lester, Lokangaka, Adrien, Tshefu, Antoinette, Goudar, Shivaprasad S., Kavi, Avinash, Esamai, Fabian, Mwenchanya, Musaku, Chomba, Elwyn, Patel, Archana, Das, Prabir, Mazariegos, Manolo, Bauserman, Melissa, Petri, William A., Krebs, Nancy F., and Derman, Richard J.

Subjects
PREGNANT women, MIDDLE-income countries, HIV-positive women, COVID-19, COVID-19 pandemic, NEONATOLOGY
Abstract

Objective: To understand trends in the knowledge, attitudes and practices (KAP) of pregnant women related to COVID‐19 in seven low‐ and middle‐income countries. Design: Multi‐country population‐based prospective observational study. Setting: Study sites in Bangladesh, the Demographic Republic of Congo (DRC), Guatemala, India (two sites), Kenya, Pakistan and Zambia. Population: Pregnant women in the Global Network's Maternal and Neonatal Health Registry (MNHR). Methods: Pregnant women enrolled in the MNHR were interviewed to assess their KAP related to COVID‐19 from September 2020 through July 2022 across all study sites. Main outcome measures: Trends of COVID‐19 KAP were assessed using the Cochran–Armitage test for trend. Results: A total of 52 297 women participated in this study. There were wide inter‐country differences in COVID‐19‐related knowledge. The level of knowledge of women in the DRC was much lower than that of women in the other sites. The ability to name COVID‐19 symptoms increased over time in the African sites, whereas no such change was observed in Bangladesh, Belagavi and Guatemala. All sites observed decreasing trends over time in women avoiding antenatal care visits. Conclusions: The knowledge and attitudes of pregnant women related to COVID‐19 varied substantially among the Global Network sites over a period of 2 years; however, there was very little change in knowledge related to COVID‐19 over time across these sites. The major change observed was that fewer women reported avoiding medical care because of COVID‐19 across all sites over time. [ABSTRACT FROM AUTHOR]

Published
2023
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49. Associations between ambient temperature and pregnancy outcomes from three south Asian sites of the Global Network Maternal Newborn Health Registry: A retrospective cohort study.

Author

Shankar, Kartik, Hwang, Kay, Westcott, Jamie L., Saleem, Sarah, Ali, Sumera A., Jessani, Saleem, Patel, Archana, Kavi, Avinash, Somannavar, Manjunath S., Goudar, Shivaprasad S., Hibberd, Patricia L., Derman, Richard J., Hoffman, Matthew, Wylie, Blair J., Goldenberg, Robert L., Thorsten, Vanessa R., McClure, Elizabeth M., and Krebs, Nancy F.

Subjects
PREGNANCY outcomes, INFANT health, MATERNAL health, RESOURCE-limited settings, PREMATURE labor
Abstract

Objective: Growing evidence suggests that environmental heat stress negatively influences fetal growth and pregnancy outcomes. However, few studies have examined the impact of heat stress on pregnancy outcomes in low‐resource settings. We combined data from a large multi‐country maternal–child health registry and meteorological data to assess the impacts of heat stress. Design: Retrospective cohort study. Setting: Three sites based in south Asia as part of the Global Network for Women's and Children's Health research in India (Belagavi and Nagpur) and Pakistan (Thatta). Population or Sample: Data from women enrolled between 2014 and 2020 in the Global Network's Maternal Newborn Health Registry (MNHR), a prospective, population‐based registry of pregnancies, were used. Methods: A total of 126 273 pregnant women were included in this analysis. Daily maximal air temperatures (Tmax) were acquired from local meteorological records. Associations between averages of daily maximal temperatures for each trimester and main outcomes were analysed using a modified Poisson regression approach. Main outcomes measures: Incidence of stillbirth, preterm birth, low birthweight (<2500 g) or evidence of pregnancy hypertension or pre‐eclampsia. Results: In the overall cohort, risk of preterm birth was positively associated with greater temperature in the second trimester (relative risk [RR] 1.05, 95% CI 1.02–1.07, p = 0.0002). Among individual sites, the risk of preterm birth was greatest in Nagpur (RR 1.07, 95% CI 1.03–1.11, p = 0.0005) and associated with second‐trimester temperature. The overall risk of low birthweight was associated with ambient temperature in second trimester (RR 1.02, 95% CI 1.01–1.04, p = 0.01). The risk for LBW was associated with first‐trimester heat in Thatta and with second‐trimester heat in Nagpur. Finally, the overall risk of gestational hypertensive disease was associated with greater temperature in the third trimester among all sites (RR 1.07, 95% CI 1.02–1.12, p = 0.005) and was particularly significant for Nagpur (RR 1.13, 95% CI 1.05–1.23, p = 0.002). These findings highlight the increased risk of detrimental obstetric and neonatal outcomes with greater temperature. Conclusion: In a multi‐country, community‐based study, greater risk of adverse outcomes was observed with increasing temperature. The study highlights the need for deeper understanding of covarying factors and intervention strategies, especially in regions where high temperatures are common. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Experiences of peer counsellors in supporting exclusive breastfeeding in southern India: An exploratory qualitative study.

Author

Charantimath, Umesh S., Bellad, Roopa M., Mahantashetti, Niranjana, Karadiguddi, Chandrashekar C., Mungarwadi, Geetanjali M., Kelly, Patricia J., Ma, Tony, Goudar, Shivaprasad S., and Derman, Richard J.

Subjects
BREASTFEEDING promotion, BREASTFEEDING, COUNSELORS, BREASTFEEDING techniques, SATISFACTION, RAPID response teams
Abstract

Objective: Peer counsellors are effective in addressing a variety of health challenges, including exclusive breastfeeding (EBF). Providing education and support from a person of similar background and experience has been an important adjunct to the practice of health workers for the past 50 years. Design: It is an exploratory qualitative study. Population or Sample: Twenty‐two peer counsellors. Setting: In‐depth Interview in the community. Methods: To better understand the experiences of these important health workers, we conducted qualitative interviews with 22 peer counsellors who participated in a research study in Belagavi District, Karnataka, India. Transcripts of the interviews were organised and assigned codes by the research team. Main outcome measures: Experience of Peer counsellor's role in the community to improve breastfeeding practices. Results: Peer counsellors had a good understanding of the larger study and of their role. Analysis of the transcripts identified three themes: personal satisfaction; the effect on the larger circle of family and community; and ideas for future programming. The positive experiences and the ability of peers to be trained in counselling women around EBF support their use in breastfeeding support and other areas of health education. Conclusions: The women from the community who served as peer counsellors were enthusiastic and satisfied about their work, which provided them with opportunities to do meaningful community work outside of their household routines. Use of the peer counsellor model to deliver a specific objective like improvement in EBF rates, immunisation or mental health in integration with healthcare providers can help in achieving desired goals. [ABSTRACT FROM AUTHOR]

Published
2023
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