283 results on '"Denis, Cécile V."'
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2. Type 2N von Willebrand disease: genotype drives different bleeding phenotypes and treatment needs
3. Fitusiran reduces bleeding in factor X–deficient mice
4. A small-molecule hemostatic agent for the reversal of direct oral anticoagulant–induced bleeding
5. Impact of allele-selective silencing of von Willebrand factor in mice based on a single nucleotide allelic difference in von Willebrand factor
6. How unique structural adaptations support and coordinate the complex function of von Willebrand factor
7. Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor
8. Angiopoietin-2 binds to multiple interactive sites within von Willebrand factor
9. Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy
10. Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models
11. A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD
12. ADP receptor P2Y12 is the capstone of the cross-talk between Ca2+ mobilization pathways dependent on Ca2+ ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets
13. Thrombin generation on vascular cells in the presence of factor VIII and/or emicizumab
14. A gain‐of‐function filamin A mutation in mouse platelets induces thrombus instability
15. Antithrombotic potential of a single‐domain antibody enhancing the activated protein C‐cofactor activity of protein S
16. New insights into regulation of αIIbβ3 integrin signaling by filamin A
17. The Role of Platelets and von Willebrand Factor in the Procoagulant Phenotype of Inflammatory Bowel Disease.
18. Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications
19. Development and characterization of single‐domain antibodies neutralizing protease nexin‐1 as tools to increase thrombin generation
20. Measuring beta‐galactose exposure on platelets: Standardization and healthy reference values
21. A single‐domain antibody that blocks factor VIIa activity in the absence but not presence of tissue factor
22. Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
23. Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity
24. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
25. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
26. A mutation of the human EPHB2 gene leads to a major platelet functional defect
27. Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis
28. NAADP/SERCA3-Dependent Ca2+ Stores Pathway Specifically Controls Early Autocrine ADP Secretion Potentiating Platelet Activation
29. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
30. Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions
31. Defect in Regulated Secretion of P-Selectin Affects Leukocyte Recruitment in von Willebrand
32. MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation
33. Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X
34. Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab
35. Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice
36. von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends
37. P.31 Von Willebrand Factor Induces Vascular Smooth Muscle Cell Proliferation and Migration Through Low Density Lipoprotein-Related Receptor Protein 4 and αvβ3 Integrin
38. Impact of PI3Kα (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis
39. Transient von Willebrand factor‐mediated platelet influx stimulates liver regeneration after partial hepatectomy in mice
40. Von Willebrand factor and cancer: Another piece of the puzzle
41. Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia
42. Mutations in the A3 domain of Von Willebrand factor inducing combined qualitative and quantitative defects in the protein
43. A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation—Brief Report
44. Emerging Therapeutic Strategies in the Treatment of Hemophilia A
45. A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor
46. Of von Willebrand factor and platelets
47. TaSER: Combining forces to stop the clot
48. Macrophage LRP1 contributes to the clearance of von Willebrand factor
49. Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA
50. Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B
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