30 results on '"Delfosse C"'
Search Results
2. Potential use of milk mid-infrared spectra to predict individual methane emission of dairy cows
- Author
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Dehareng, F., Delfosse, C., Froidmont, E., Soyeurt, H., Martin, C., Gengler, N., Vanlierde, A., and Dardenne, P.
- Published
- 2012
- Full Text
- View/download PDF
3. 15-year follow-up of a case of amelogenesis imperfecta: importance of psychological aspect and impact on quality of life
- Author
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Trentesaux, T., Rousset, M. M., Dehaynin, E., Laumaillé, M., and Delfosse, C.
- Published
- 2013
- Full Text
- View/download PDF
4. Composition of bone and apatitic biomaterials as revealed by intravital Raman microspectroscopy
- Author
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Penel, G., Delfosse, C., Descamps, M., and Leroy, G.
- Published
- 2005
- Full Text
- View/download PDF
5. La Carie Précoce Du Jeune Enfant
- Author
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Delfosse, C., Trentesaux, T., Delfosse, C., and Trentesaux, T.
- Abstract
La carie précoce du jeune enfant est une forme sévère de la maladie carieuse qui touche les jeunes enfants. Elle est considérée par de nombreux auteurs comme la maladie chronique la plus répandue chez les enfants d'âge préscolaire. Cet ouvrage détaille cette pathologie et explique comment prendre en charge ces jeunes patients dès les premiers signes de la maladie, mais aussi comment mettre en place au sein de leur entourage les comportements propices à un non-développement de la maladie carieuse.
- Published
- 2016
6. Employment and farmers' work in European ruminant livestock farms: A review.
- Author
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Hostiou, N., Vollet, D., Benoit, M., and Delfosse, C.
- Subjects
LIVESTOCK farms ,EMPLOYMENT ,DAIRY farms ,FARMERS ,GOVERNMENT policy ,LIVESTOCK breeds - Abstract
Agricultural employment, in sharp decline in Europe, is the subject of little recent scientific work, and few studies focus specifically on livestock farming. Labour and employment factors must be considered to respond appropriately to the livestock farming "crisis" in Europe and to assess the room to manoeuvre of public policies to adapt this sector to the diverse challenges facing it. We have conducted a review to assess the combined effects on ruminant livestock employment and famers' work at the European level. In the first section, employment in ruminant livestock farms is quantified and the main differences between livestock sectors and regions are identified. We have showed that in France, livestock activities mobilize 41% of the French agricultural workforce at the national level, but due to territorial diversity, there are significant variations across the country. In Europe, while all countries are affected by a reduction in the livestock workforce, employment trends also vary depending on the animal sector. In the second section, we analyse trends in farmers' work that could explain the evolution of agricultural employment in terms of slowing or accelerating the reduction in the livestock workforce. Our results highlighted supply-driven factors and demand-driven factors tend to increase the number of livestock workers. Some structural and institutional changes play a greater role as both an accelerator and moderator of the decline in livestock workers. The third section focuses on the effects of livestock employment on other industries. We show that the indirect and induced effects of livestock farming vary according to activity sector. Dairy farms have higher induced effects, especially at the national level. The development of processing activities can be limited locally by the low appeal of most of the jobs. In the conclusion, we highlight four major issues concerning employment and work in the livestock sector at the European level. • In Europe, mixed livestock and mixed crop-livestock farms have the largest employment decline. • In Europe, the number of livestock farmers fell, except in Spain and the Netherlands. • Supply-driven factors and demand-driven factors tend to increase the number of livestock workers. • Some structural and institutional changes play a greater role for the decline in livestock workers. • The indirect and induced effects of livestock farming vary according to activity sector : dairy farms have higher induced effects. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
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7. Study of the hooking behaviour of Lepeophtheirus salmonis (Krøyer, 1837) copepodids on Atlantic salmon, Salmo salar L., using a novel in vivo test system.
- Author
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Delfosse, C, Lafont‐Lecuelle, C, Barthélémy, H, Chabaud, C, Teruel, E, Bienboire‐Frosini, C, and Pageat, P
- Subjects
- *
LEPEOPHTHEIRUS salmonis , *ATLANTIC salmon , *PATHOGENIC microorganisms , *FISH parasites , *AQUACULTURE - Abstract
The screening of putative semiochemicals involved in the interaction between Lepeophtheirus salmonis copepodid and the Atlantic salmon could be used to develop methods to prevent infestation. A bioassay was designed to evaluate the attractiveness of Atlantic salmon for L. salmonis copepodids by counting the number of hooked parasites. A salmon was bathed in a tank with 60 copepodids during 45 min. The salmon was humanely killed and its body was scrubbed above a plastic bag. The content of the bag was filtered to count the number of hooked parasites. This procedure was tested at different water temperatures and for different body mass. The temperature significantly influenced the number of hooked copepodids (p < .05). Smolts presented significantly more hooked copepodids at a higher water temperature (24.6 at 13.8°C) compared to smolts at a lower temperature (18.6 at 6.1°C; p = .011). No correlation was found between the body mass and the number of hooked parasites (p = .65). This bioassay was used to successfully measure the attractiveness of Atlantic salmon for L. salmonis copepodids, making it an interesting tool to screen putative semiochemicals designed to prevent the infestation. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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8. CL7 - LA RECHERCHE EN ÉTHIQUE, UN OUTIL POUR DÉVELOPPER L’ÉDUCATION THÉRAPEUTIQUE EN ODONTOLOGIE PÉDIATRIQUE
- Author
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Trenteseaux, T, Delfosse, C, Rousset, M M, Hervé, C, and Hamel, O
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Teaching - Published
- 2011
9. Extending the Canada-France brown Dwarfs Survey to the near-infrared: first ultracool brown dwarfs from CFBDSIR
- Author
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Delorme L. Albert T. Forveille E. Artigau X. Delfosse C. Reylé C.J. Willott E. Bertin F. Allard, P., Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)
- Subjects
ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2010
10. Occlusion and rhythm of eruption
- Author
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Rousset, M M, Boualam, N, and Delfosse, C
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stomatognathic diseases ,stomatognathic system - Abstract
span style="font-size: 12px; line-height: 14px" class="Apple-style-span"Occlusion through successive phases of dental eruption was the concern of many authors. So that the progressive installation of occlusion is made harmonious way, it is necessary that the dental eruption sequences proceed correctly. The authors have studied rhythm appearance of permanent teeth, and they have determined the average eruption age of canines, first, second premolar and second molar. The results are given for the 574 children of the sample and following to the sex./span
- Published
- 2008
11. Finding ultracool brown dwarfs with MegaCam on CFHT: method and first results
- Author
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Delorme C.J. Willott T. Forveille X. Delfosse C. Reylé E. Bertin L. Albert E. Artigau A.C. Robin F.Allard R. Doyon G. J. Hill, P., Institut Bisontin en Sciences Fondamentales (IBSF), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)
- Subjects
[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] - Published
- 2008
12. Effect of a Laser irradiation on the vascularisation of safety and X-ray radiated bone.
- Author
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Desmons, S., Delfosse, C., Rochon, P., Buys, B., Penel, G., and Mordon, S.
- Published
- 2007
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13. CL7 - ETHICS RESEARCH, A TOOL FOR DEVELOPING THERAPEUTIC EDUCATION IN PAEDIATRIC DENTISTRY.
- Author
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Trentesaux, T., Delfosse, C., Rousset, M. M., Hervé, C., and Hamel, O.
- Published
- 2011
14. Structures et stereochimie des sesquiterpenes de Penicillium roqueforti pr toxine et eremofortines a, b, c, d, e
- Author
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Moreau, S., Biguet, J., Lablache-Combier, A., Baert, F., Foulon, M., and Delfosse, C.
- Published
- 1980
- Full Text
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15. Emergence of permanent teeth: secular trends and variance in a modern sample.
- Author
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Rousset M, Boualam N, Delfosse C, and Roberts WE
- Published
- 2003
16. Pain during primary molar local anaesthesia with SleeperOne5 computerized device versus conventional syringe: A randomized, split-mouth, crossover, controlled trial.
- Author
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Muller-Bolla M, Aïem E, Joseph C, Davit-Béal T, Marquillier T, Esclassan E, Delfosse C, Lopez S, and Velly AM
- Subjects
- Humans, Male, Child, Female, Child, Preschool, Syringes, Anesthetics, Local administration & dosage, Cross-Over Studies, Molar, Anesthesia, Dental methods, Anesthesia, Dental instrumentation, Tooth, Deciduous, Anesthesia, Local instrumentation, Anesthesia, Local methods, Pain Measurement
- Abstract
Background: Because of controversial results from clinical studies comparing different dental local anesthesia methods in children, the primary objective of this randomized, split-mouth, crossover, controlled trial was to compare pain intensity during local anaesthesia (LA) performed with a computer-controlled LA delivery system (C-CLADS) versus a conventional syringe (CONV). Secondary objectives included comparisons during dental treatment., Methods: Participants (4-8 years) with tooth pair requiring similar treatment were recruited from five French hospitals. The right primary molar, which was treated at the first visit, was randomly allocated to one of the anaesthesia groups (either intraosseous with C-CLADS or infiltration with CONV), whereas the contralateral molar (treated at the second visit) was assigned to the other group. Pain intensity and behaviour outcomes, assessed with the Faces Pain and Venham revised scales, respectively, were compared between groups using Proc mixed. Stratified analyses were performed on dentition and location., Results: Among 107 participants, the analysis revealed reduced pain perception during LA in the C-CLADS group compared with the CONV group (-0.72, 95% CI: -1.43, -0.006), but not during dental treatment. Stratified analyses showed that this effect was observed only in primary dentition (p = .006) and mandibular molars (p = .005). Behavioural issues were fewer in the C-CLADS group than in the CONV group (p = .05) only during injection., Conclusion: C-CLADS emerged as the preferable system in primary dentition., (© 2024 BSPD, IAPD and John Wiley & Sons Ltd.)
- Published
- 2024
- Full Text
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17. Development of impression trays for treating infants with trisomy 21 before their deciduous teeth erupt.
- Author
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Dobrenel J, Delfosse C, Chai F, Vandomme J, Denis C, and Dehurtevent M
- Abstract
The treatment of infants with trisomy 21 (TS21) with a myostimulation plate can improve their development and quality of life. The manufacture of these plates requires an accurate cast of the maxilla, and their efficacy relies on their stability and retention. As such, the quality of the impression is a determining factor. The lack of commercially available stock trays for infants with TS21 creates difficulties, including inadequate impression quality and the risk of inhaling impression material. The present technique simplifies impression making for infants with TS21 from 3 months of age to when their maxillary deciduous teeth erupt by using computer-aided design and computer-aided manufacturing (CAD-CAM) impression trays. Sixty-five stored gypsum maxillary casts from infants with TS21 that had been used to manufacture myostimulation plates were analyzed to select four differently sized representative casts for designing the impression trays. A CAD software program was used to digitally shape four sizes of the impression tray from the selected gypsum casts. Practitioners interested in this approach can download and export the standard tessellation language (STL) files using a quick response (QR) code. The impression trays should be manufactured with the stereolithography additive technique using biocompatible resin. This technique allows practitioners to make accurate maxilla impressions for infants with TS21 by manufacturing their own impression trays using the free-access STL files rather than the cumbersome conventional method., (Copyright © 2023 Editorial Council for The Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
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18. The inception of a hospital-based dental emergency department in a precarious region decreases the incidence of severe cellulitis of odontogenic origin.
- Author
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Nicot R, Barry F, Raoul G, Wiel E, Delfosse C, Ferri J, Nawrocki L, and Lauwers L
- Subjects
- Humans, Incidence, Retrospective Studies, Hospitals, Cellulitis epidemiology, Cellulitis etiology, Cellulitis therapy, Emergency Service, Hospital
- Abstract
Introduction: Although most localized odontogenic infections can be managed successfully without complications, some can cause extensive morbidity through the onset of cervicofacial cellulitis. The management of these more severe infections generally requires emergency treatment, including surgical treatment under general anesthesia, and prolonged length of hospital stay., Material & Methods: In this work, we assessed the impact of the provision of a hospital-based dental emergency department on the regional incidence of severe odontogenic cellulitis in a socioeconomically precarious region. Monthly case rates of odontogenic cellulitis treated between January 2010 and December 2019 at the hospital-based dental emergency department of Lille Medical University Hospital were collected., Results: The mean number of monthly severe odontogenic cellulitis cases treated under general anesthesia was significantly higher before than after the inception of the hospital-based dental emergency service [14.07 (5.83) vs 8.79 (4.42); p<0.0001]. Conversely, the monthly mean number of collected odontogenic cellulitis cases treated under local anesthesia was significantly lower before the emergency service was set up [22.42 (12.73) vs 43.32 (23.41); p<0.0001]., Conclusion: The provision of a hospital-based dental emergency department resulted in a decrease in severe dental infections in a region with high indices of socioeconomic precarity, morbidity and mortality. Greater accessibility to dental care allows for the rationalization of care through more precocious and fewer burdensome procedures., Competing Interests: Declaration of Competing Interest None., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)
- Published
- 2022
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19. Which determinants should be considered to reduce social inequalities in paediatric dental care access? A cross-sectional study in France.
- Author
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Marquillier T, Trentesaux T, Pierache A, Delfosse C, Lombrail P, and Azogui-Levy S
- Subjects
- Child, Preschool, Cross-Sectional Studies, Female, France epidemiology, Health Knowledge, Attitudes, Practice, Humans, Male, Oral Health, Parents education, Prevalence, Self Efficacy, Vulnerable Populations statistics & numerical data, Dental Care statistics & numerical data, Dental Caries epidemiology, Parents psychology, Socioeconomic Factors
- Abstract
Better access to dental care through systemic and educational strategies is needed to lessen the burden of disease due to severe early caries. Our study aims to describe family characteristics associated with severe early caries: parental knowledge, attitudes, practices in oral health and socio-demographic factors. For this cross-sectional study, 102 parents of children aged under 6 years with severe early caries and attending paediatric dentistry service in France completed a questionnaire during face-to-face interviews. Caries were diagnosed clinically by calibrated investigators, using the American Academy of Paediatric Dentistry criteria, and dental status was recorded using the decayed, missing, and filled teeth index. The majority of children were from underprivileged backgrounds and had poor oral health status, with a median dmft index of 10. Parents highlighted the difficulty of finding suitable dental care in private practices. Parents appeared to have good oral health knowledge and engaged in adapted behaviours but showed a low sense of self-efficacy. They perceived the severity of early caries as important but the susceptibility of their child as moderate. The study affirmed the importance of improving the accessibility of paediatric dental care and developing educational strategies to enhance the knowledge, skills, and oral health practices of families., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2021
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20. Effect of handling and crowding on the susceptibility of Atlantic salmon (Salmo salar L.) to Lepeophtheirus salmonis (Krøyer) copepodids.
- Author
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Delfosse C, Pageat P, Lafont-Lecuelle C, Asproni P, Chabaud C, Cozzi A, and Bienboire-Frosini C
- Subjects
- Animals, Aquaculture methods, Copepoda physiology, Crowding, Ectoparasitic Infestations prevention & control, Fish Diseases blood, Fish Diseases prevention & control, Hydrocortisone blood, Lymphocytes, Neutrophils, Salmo salar, Ectoparasitic Infestations parasitology, Fish Diseases parasitology, Stress, Physiological
- Abstract
Lepeophtheirus salmonis is an ectoparasite causing economic concerns in Atlantic salmon farming. Salmon lice infestation management methods can be stressful and impact fish welfare. This work investigated the stress effect on the attachment of L. salmonis copepodids to Atlantic salmon through two approaches: (a) handling by netting and air exposure (acute stress), and (b) crowding with restricted surface access in a tank (chronic stress). In the first experiment, we compared the number of attached L. salmonis and cortisol levels between a group of handled salmon and a control group. In the second experiment, a group of densely packed salmon was compared to a control group based on the number of attached copepodids, cortisol levels and neutrophil:lymphocyte ratios. Handled salmon showed significantly higher plasma cortisol levels (p < .001) and more attached copepodids (p = .01) than control salmon. Conversely, the cortisol level and number of attached copepodids were not significantly different between the densely packed and control salmon (p > .05). The neutrophil:lymphocyte ratio was significantly higher (p = .0014) in the densely packed salmon than in the control salmon. Handling salmon increased their risk of infestation by L. salmonis. This has implications for reinfestation rates following delousing treatments in commercial salmon aquaculture, which often involve crowding and handling salmon., (© 2020 The Authors. Journal of Fish Diseases published by John Wiley & Sons Ltd.)
- Published
- 2021
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21. Masticatory behavior for different solid foods in preschool children according to their oral state.
- Author
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Linas N, Peyron MA, Hennequin M, Eschevins C, Nicolas E, Delfosse C, and Collado V
- Subjects
- Cheese, Child, Preschool, Deglutition physiology, Feeding and Eating Disorders, Female, France, Humans, Male, Mouth, Prospective Studies, Quality of Life, Biomechanical Phenomena, Feeding Behavior, Foods, Specialized, Mastication physiology
- Abstract
Gradual introduction of solid foods in early childhood takes part in the maturation of mastication. The impact of any oral state alteration on food oral processing development is poorly documented for this age group. This study investigated the masticatory behavior in 3 to 6 year-old children with or without early childhood caries (ECC) for three solid foods of different textures. Twenty-one children with healthy oral state and 23 children with severe ECC were observed during complete mastication of calibrated samples of raw carrot, cheese and breakfast cereals. Food refusals and kinematic parameters (Ti: chewing time, Nc: number of cycles and Fq: chewing frequency) were used to assess children masticatory behavior. Oral Health-related Quality of Life and orofacial dysfunctions were evaluated using, respectively the early childhood oral health impact scale (ECOHIS) and the Nordic orofacial dysfunction test screening (NOT-S). Children suffering from ECC exhibited significantly higher ECOHIS and NOT-S scores, in particular for the mastication domain. Accordingly, lower chewing frequencies values were recorded in children with ECC (i.e., carrot Fq: 1.21 ± 0.20 vs 1.35 ± 0.22, p ≤ 0.01), as well as more frequent refusals for carrots. Kinematic parameters were shown to be repeatable in all children for successive samples of the same food, and tended to vary depending on the proposed food. Some masticatory behavior regulation according to food properties could already be present in preschool children. Children with ECC developed alternative behavioral strategies to overcome feeding difficulties. Further studies should investigate food bolus properties according to oral health, as well as nutritional issues. PRACTICAL APPLICATIONS: During childhood, the way solid foods are processed in the oral cavity to be safely swallowed and then digested in available nutrients, is poorly documented. In this study, preschool children have been shown to repeatedly adapt their masticatory behavior to a given food. The collection of various food boli as recorded at the moment of swallowing could then be considered in further food bolus properties research investigations. Moreover, this study suggested that children with altered dentition modified their masticatory kinematic parameters and developed alternative strategies, including food or texture selection, to overcome their feeding difficulties. The development of a mastication evaluation protocol could help medical professionals to detect children masticatory deficiencies and then propose diet adaptations. Considering the importance of food diversity in mastication development and maturation, food industries may consider to develop a range of texture adapted foods for young children, especially designed to gradually rehabilitate the masticatory function., (© 2019 Wiley Periodicals, Inc.)
- Published
- 2019
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22. Obstacles to comprehensive dental care in patients with sustained limitations of their decision-making abilities: findings from a Delphi study.
- Author
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Blaizot A, Catteau C, Delfosse C, Hamel O, and Trentesaux T
- Subjects
- Aged, Child, Consensus, Decision Making, Delphi Technique, Dental Care for Aged, Dental Care for Children, Dental Care for Persons with Disabilities, Dentists, France, Humans, Surveys and Questionnaires, Comprehensive Dental Care, Health Services Accessibility, Mental Competency
- Abstract
The objective of this study was to explore the therapeutic limitations experienced by a panel of special-care dentists in France when treating patients with sustained limitations of their decision-making abilities. We used a Delphi technique conducted in three rounds from 01 June 2014 to 30 September 2015. A first questionnaire comprising open-ended questions was addressed to 72 panellists. A content analysis of the returned questionnaires served to draft a second questionnaire comprising closed-ended questions; this was sent to the 28 panellists who responded in the first round. A third questionnaire was sent to the 20 panellists who responded in the second round to give them an opportunity to reconsider their response in the context of the second-round response group. Sixteen panellists answered the last round. A large majority agreed on the importance of providing comprehensive care, but they encountered obstacles at two time points: (i) when proposing the care; and (ii) when setting it up. The panel put forward recommendations in two main areas: (i) the training of those involved in oral health decisions; and (ii) dental care management and organization of the care system. The study provided a foundation for building future orientations in health care for patients with limited decision-making abilities., (© 2018 Eur J Oral Sci.)
- Published
- 2018
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23. Impact of early childhood caries and its treatment under general anesthesia on orofacial function and quality of life : A prospective comparative study.
- Author
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Collado V, Pichot H, Delfosse C, Eschevins C, Nicolas E, and Hennequin M
- Subjects
- Age Factors, Child, Child, Preschool, Face physiology, Female, Humans, Male, Mouth physiology, Prospective Studies, Anesthesia, General, Dental Caries therapy, Quality of Life
- Abstract
Background: Early Childhood Caries (ECC) has become a major public health concern worldwide, mostly affecting children from disadvantaged families in increasingly severe forms. This condition has been frequently reported to alter children's nutrition, growth and general development. It negatively impacts their quality of life, through painful episodes and severe eating difficulties. While this period is crucial for oral praxes development, the impact of dental state on oro-facial functions is poorly documented. This study evaluated the impact of ECC and its treatment under general anesthesia on oro-facial functions and quality of life in pre-school children., Material and Methods: The dysfunction and quality of life scores from 25 children with ECC were evaluated before treatment (T0), one month (T1) and three months after treatment (T2), using the Nordic Orofacial Test-Screening (NOT-S) and the Early Childhood Oral Health Impact Scale (ECOHIS), respectively, in comparison with 16 caries-free children. The number and extent of inter-arch dental contacts were also observed., Results: The pre-operative higher NOT-S score observed in children with ECC decreased to reach the control level at T2. The mastication item was the most affected in the ECC group throughout the study. Their mean ECOHIS score also significantly decreased post-operatively and differences remaining between both groups were no longer clinically relevant. In addition, in children with ECC, values of functional inter-arch surfaces tended to increase over the follow-up period., Conclusions: Oro-facial functions and quality of life, altered by ECC, could be restored through a conservative treatment approach. Relations between dental state, orofacial functions and particularly chewing, and nutrition should be investigated further.
- Published
- 2017
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24. Social vulnerability in paediatric dentistry: an overview of ethical considerations of therapeutic patient education.
- Author
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Trentesaux T, Delfosse C, Rousset MM, Hervé C, and Hamel O
- Subjects
- Child, Chronic Disease epidemiology, Chronic Disease therapy, Humans, Vulnerable Populations statistics & numerical data, Dental Caries epidemiology, Dental Caries therapy, Patient Education as Topic ethics, Pediatric Dentistry ethics
- Abstract
Dental caries is a multifactorial condition that remains a major public health issue in high income countries. The prevalence of dental caries in children has markedly declined in most countries over the past 30 years. However, the disease continues to affect a vulnerable population defined as a high-risk group. As many public health policies are inefficient in dealing with this underprivileged group, it is necessary to find other strategies to decrease the incidence and the burden of dental caries. Defining dental caries as a chronic disease enables us to develop the concept of 'therapeutic patient education.' It is meant to train patients to self-manage or adapt treatment to their particular chronic disease and to cope with new processes and skills. The purpose of this paper is to propose a new approach to dental caries, in particular to early childhood caries. That should decrease the gravity and prevalence of the disease in this specific population. As a result, this new approach could increase the quality of life of many children both in terms of function and aesthetics.
- Published
- 2014
- Full Text
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25. Structural equation models to estimate risk of infection and tolerance to bovine mastitis.
- Author
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Detilleux J, Theron L, Duprez JN, Reding E, Humblet MF, Planchon V, Delfosse C, Bertozzi C, Mainil J, and Hanzen C
- Subjects
- Animal Husbandry, Animals, Bacteria isolation & purification, Cattle, Data Interpretation, Statistical, Female, Mastitis, Bovine etiology, Mastitis, Bovine microbiology, Milk microbiology, Risk Factors, Disease Resistance, Mastitis, Bovine epidemiology, Models, Statistical
- Abstract
Background: One method to improve durably animal welfare is to select, as reproducers, animals with the highest ability to resist or tolerate infection. To do so, it is necessary to distinguish direct and indirect mechanisms of resistance and tolerance because selection on these traits is believed to have different epidemiological and evolutionary consequences., Methods: We propose structural equation models with latent variables (1) to quantify the latent risk of infection and to identify, among the many potential mediators of infection, the few ones that influence it significantly and (2) to estimate direct and indirect levels of tolerance of animals infected naturally with pathogens. We applied the method to two surveys of bovine mastitis in the Walloon region of Belgium, in which we recorded herd management practices, mastitis frequency, and results of bacteriological analyses of milk samples., Results and Discussion: Structural equation models suggested that, among more than 35 surveyed herd characteristics, only nine (age, addition of urea in the rations, treatment of subclinical mastitis, presence of dirty liner, cows with hyperkeratotic teats, machine stripping, pre- and post-milking teat disinfection, and housing of milking cows in cubicles) were directly and significantly related to a latent measure of bovine mastitis, and that treatment of subclinical mastitis was involved in the pathway between post-milking teat disinfection and latent mastitis. These models also allowed the separation of direct and indirect effects of bacterial infection on milk productivity. Results suggested that infected cows were tolerant but not resistant to mastitis pathogens., Conclusions: We revealed the advantages of structural equation models, compared to classical models, for dissecting measurements of resistance and tolerance to infectious diseases, here bovine mastitis. Using our method, we identified nine major risk factors that were directly associated with an increased risk of mastitis and suggested that cows were tolerant but not resistant to mastitis. Selection should aim at improved resistance to infection by mastitis pathogens, although further investigations are needed due to the limitations of the data used in this study.
- Published
- 2013
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26. A preliminary investigation into the effects of X-ray radiation on superficial cranial vascularization.
- Author
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Desmons S, Heger M, Delfosse C, Falgayrac G, Sarrazin T, Delattre C, Catros S, Mordon S, and Penel G
- Subjects
- Animals, Blood Vessels pathology, Blood Vessels physiopathology, Blood Vessels radiation effects, Bone Regeneration physiology, Disease Models, Animal, Female, Image Cytometry, Microcirculation physiology, Neovascularization, Physiologic physiology, Osteoradionecrosis physiopathology, Rabbits, Radiation Dosage, Recovery of Function physiology, Recovery of Function radiation effects, Skull physiopathology, X-Rays adverse effects, Bone Regeneration radiation effects, Microcirculation radiation effects, Neovascularization, Physiologic radiation effects, Osteoradionecrosis pathology, Skull blood supply, Skull radiation effects
- Abstract
Radiation therapy (RT) is an established treatment modality for malignant neoplasms. RT induces tissue damage that may lead to osteoradionecrosis in more severe cases. Suitable animal models to study RT-induced changes in membranous craniofacial bone are currently not available. The aim of this study was therefore to quantify RT-induced changes in cranial microcirculation using a newly developed calvaria chamber model and to relate these changes to RT-induced histological damage. New Zealand white rabbits received a total radiation dose of 18.75 Gy through the calvaria chamber, and the number of vessels, the vessel length density (VLD), and angiogenic sprouting were quantified on a weekly basis during a 12-week period. At the end of 12 weeks, the RT-treated (n = 5) or control (n = 5) calvarias were biopsied for histopathological analysis. RT resulted in a steep reduction in the number of vessels and the VLD during the first 3 weeks, particularly in larger-diameter vessels, followed by a flat stabilization/remodeling phase in the subsequent 9 weeks that never restored to baseline values. Histomorphometric analysis revealed a high degree of osteocytic depletion, prominent hypocellularity in the lacunae and intraosseous vasculature, enlarged and nonconcentric Haversian systems, and a severely disorganized bone matrix in the RT-treated calvarias. Despite the prevalence of some angiogenic potential, the RT-induced effects in the early phase persisted in the intermediate to late phase, which may have contributed to the poor recovery of the RT-treated bone.
- Published
- 2009
- Full Text
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27. Effect of a laser irradiation on the vascularisation of safety and X-ray radiated bone.
- Author
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Desmons S, Delfosse C, Rochon P, Buys B, Penel G, and Mordon S
- Subjects
- Animals, Dose-Response Relationship, Radiation, Rabbits, Radiation Dosage, Skull cytology, Skull radiation effects, Lasers, Neovascularization, Physiologic physiology, Neovascularization, Physiologic radiation effects, Skull blood supply, Skull physiology, X-Rays
- Abstract
Thermal preconditioning induces a cytoprotective effect and promotes tissue recovering. Laser is an appropriated method to generate a controlled and reproducible heating. Bone healing, a crucial challenge in medicine, is affected by X-ray radiation which induces a chronic antiangiogenic effect. So, this study aims to investigate the role of laser preconditioning on the vascularisation of bone after X-ray radiation. An optical bone chamber allowed the study of the vascularization process. The vascular density (VD) was determined using image processing. A longitudinal study was performed on 20 rabbits divided in four groups: #1: control group (n=5); #2: laser irradiation alone (diode laser 810nm, fluence= 48J/cm2) (n=5). #3: X-ray radiation (18.75Gy) alone (n=5), #4: laser preconditioning 24 hours before a X-ray radiation (n=5). VD remained stable during 12-week follow up for groups #1 and #2. X-ray radiation lead to an important decrease of the superficial bone vascularization in group #3. The decrease of the vascularization was limited in group #4 highlighting a different evolution between group #3 and #4. Those results were confirmed by histological analysis. Our preliminary findings show that laser preconditioning preserves vascularization in X-ray radiated bone site, outlining a novel approach for the bone healing in which the vascular supply has been injured.
- Published
- 2007
- Full Text
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28. Biological characterization of experimental carbon samples.
- Author
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Delfosse C, Monchau F, Lefevre A, Maquin D, Lafforgue P, and Hildebrand HF
- Subjects
- Biocompatible Materials toxicity, Carbon toxicity, Carbon Fiber, Cell Adhesion, Cell Division, Cell Line, Cell Size, Cell Survival, Epithelial Cells cytology, Giant Cells pathology, Humans, Keratinocytes cytology, Lung cytology, Lung embryology, Skin cytology, Surface Properties, Vacuoles ultrastructure, Biocompatible Materials chemistry, Carbon chemistry
- Abstract
The use of carbon is widespread in fields as wide as aeronautics, cars, electricity or electronics. The biomedical applications of carbon are also numerous. The purpose of our work is to test four experimental carbon fibers (A, B, C and D; B being the negative control) to determine the best clinical application. Four tests of cytocompatibility are carried out (cell viability, inflammatory test, cell proliferation and cell morphology). Two different cell lines are used: the L132 cell line (epithelial embryonic pulmonary human cell) and the HaCaT line (human normal spontaneously immortalized skin keratinocytes). The results of the biological tests are compared with those of a carbon fiber sample already marketed as a bandage in the treatment of infected wounds: Actisorb "Plus (J2). The various tests show us that only two experimental samples are slightly cytotoxic (A, D). On the other hand, no sample supports cell adherence. A, B, C and D do not have an inflammatory effect. J2 appears at the same time cytotoxic and inflammatory. Consequently, being given the physical presentation and the biological properties of experimental samples (A, C and D), we intend them for an application in the field of wound healing, as a bandage. Also further experimentation is needed.
- Published
- 2002
29. Occlusion and rhythm of eruption.
- Author
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Rousset MM, Boualam N, and Delfosse C
- Subjects
- Adolescent, Age Factors, Algorithms, Bicuspid physiology, Case-Control Studies, Child, Child, Preschool, Circadian Rhythm physiology, Cuspid physiology, Female, Humans, Male, Mandible, Maxilla, Molar physiology, Probability, Sex Factors, Statistics as Topic, Dental Occlusion, Tooth Eruption physiology
- Abstract
Occlusion through successive phases of dental eruption was the concern of many authors. So that the progressive installation of occlusion is made harmonious way, it is necessary that the dental eruption sequences proceed correctly. The authors have studied rhythm appearance of permanent teeth, and they have determined the average eruption age of canines, first, second premolar and second molar. The results are given for the 574 children of the sample and following to the sex.
- Published
- 2001
30. Computer model for simulation of emergency medical systems.
- Author
-
Fletcher JR, Bond JC, Delfosse C, and Richards PB
- Subjects
- Humans, Transportation of Patients, United States, Computers, Emergency Medical Services, Models, Theoretical, Naval Medicine
- Published
- 1979
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