111 results on '"Deacon, Andrew"'
Search Results
2. Building Capabilities: Using MOOCs to Make Transitions in Work
- Author
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Small, Janet, Deacon, Andrew, Walji, Sukaina, Jaffer, Tasneem, and Jawitz, Jeff
- Abstract
Our research explores the experience of adults looking for flexible online learning opportunities that intersect with university study. We interviewed 58 people living in 14 African countries who have taken a Massive Open Online Course (MOOC) developed by the University of Cape Town. The interview data reveals diverse uses of MOOCs in workplace contexts. While only two of those we interviewed articulated a goal of making a career change, there were many more taking a MOOC for some form of self-development within their current profession. There were also cases where people had not yet identified a new career, but believed the knowledge and skills would support future transitions. Our intentions for exploring the expectations of MOOC takers regionally is to improve our understanding of how universities, following open practices, could support the educational aspirations of this audience through the provision of flexible online learning opportunities.
- Published
- 2019
3. Mathematical Errors Made by High Performing Candidates Writing the National Benchmark Tests
- Author
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Bohlmann, Carol A., Prince, Robert N., and Deacon, Andrew
- Abstract
When the National Benchmark Tests (NBTs) were first considered, it was suggested that the results would assess entry-level students' academic and quantitative literacy, and mathematical competence, assess the relationships between higher education entry-level requirements and school-level exit outcomes, provide a service to higher education institutions with regard to selection and placement, and assist with curriculum development, particularly in relation to foundation and augmented courses. We recognise there is a need for better communication of the findings arising from analysis of test data, in order to inform teaching and learning and thus attempt to narrow the gap between basic education outcomes and higher education requirements. Specifically, we focus on identification of mathematical errors made by those who have performed in the upper third of the cohort of test candidates. This information may help practitioners in basic and higher education. The NBTs became operational in 2009. Data have been systematically accumulated and analysed. Here, we provide some background to the data, discuss some of the issues relevant to mathematics, present some of the common errors and problems in conceptual understanding identified from data collected from Mathematics (MAT) tests in 2012 and 2013, and suggest how this could be used to inform mathematics teaching and learning. While teachers may anticipate some of these issues, it is important to note that the identified problems are exhibited by the top third of those who wrote the Mathematics NBTs. This group will constitute a large proportion of first-year students in mathematically demanding programmes. Our aim here is to raise awareness in higher education and at school level of the extent of the common errors and problems in conceptual understanding of mathematics. We cannot analyse all possible interventions that could be put in place to remediate the identified mathematical problems, but we do provide information that can inform choices when planning such interventions.
- Published
- 2017
4. Drugs affecting the heart: anti-hypertensives
- Author
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Knapp, Claire A. and Deacon, Andrew
- Published
- 2021
- Full Text
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5. Measurement of pulse oximetry, capnography and pH
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Deacon, Andrew J. and Pratt, Oliver W.
- Published
- 2021
- Full Text
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6. Expression of green fluorescent protein (GFP) in Leishmania spp. to identify survival strategies the parasite imposes on the human host
- Author
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Deacon, Andrew D., Getti, Giulia, and Harbige, Laurence
- Subjects
616.9 ,QD Chemistry ,RS Pharmacy and materia medica - Abstract
Leishmania protozoa are the etiological agent of human disease known as leishmaniasis. There are three main forms of this disease, whose manifestation depends on a number of factors including the infecting Leishmania species and the immunological status of the individual. Disease development requires extracellular form of the parasite, the promastigotes to be internalised, transform and replicate as intracellular amastigotes within mammalian cells. Once inside host cells parasites they regulate and control immune responses from inside the host cells through the modulation of protein expression including cytokines. The changes involving Leishmania promastigote and host cells is well documented during the early stage of infection. However, little is known on the modulative effect of L. aethiopica and L. mexicana during infection of host cells. It is key to have an altruistic approach to when studying the different Leishmania spp during host infection, as it is a key factor in the outcome of type of leishmaniasis. The study of infection is complicated by the inherent difficulty of detecting intracellular parasites, as many methods are laborious and time consuming (microscopy with Giemsa staining). Implementation of fluorescent expressing parasites has been successfully used in a number of species to observe and quantify cellular infection. Although successful stable genetically modified Leishmania parasites are not available for L. mexicana and L. aethiopica, this research aims to investigate survival mechanisms such as cytokine and protein expression during the early stages of infection. This requires monitoring infection as the first step, which involved developing for the first time constitutively expressing GFP in L. aethiopica, L. major, L. mexicana and L. tropica. The effect of infection on host macrophages was directly quantified via comparative proteomics which identified significant differences in protein expression not only between uninfected and infected cells at late stages of infection but also between different species. The effect of infection on the ability of controlling host and neighbouring cells was further characterised by looking at cytokine & antimicrobial peptide expression, including TNFα, IL-10, TGFβ, IL-1RA and cathelicidin at various time points during L. aethiopica infection. As cytokine expression is closely linked to manipulation of T-cells, which are also know to be ultimately responsible for disease exacerbation/resolution, the effect of the parasites on such cells was further investigate. A novel role for T cells on infection was explored, specifically their ability to host parasites. The successful stable integration of GFP expression in four Leishmania spp. was confirmed by PCR, western blot, fluorescent microscopy and flow cytometry (N=3). These parasites allowed the monitoring of infection in macrophages whilst investigating the expression of cytokines, proteins, and novel human cell types. Cathelicidin expression was shown to increase during the early stages of infection at 8hrs following by a steady decline towards 48hrs post infection. The anti-inflammatory cytokine IL-10 expression was shown to increase from 2-48hrs peaking at the latest point with >3-fold difference post infection. Interestingly, the inflammatory cytokine TNFα showed expression increased from 2-48hrs, peaking with >5-fold at 48hrs post infection. Both these cytokines have been shown to peak at 8 hours followed by a decline, which may indicate subtle differences at a species (Lapara and Kelly 2010). Proteinomic study revealed L. mexicana and L. aethiopica both up-regulated a total of eight proteins with only two that were influenced by both species (N=3). In addition, down regulation was only identified during infection with L. aethiopica and not L. mexicana. However, during upregulation, the proteins identified were found to be involved in endocytosis (actin), immunological responses (MHC I), free radical scavenging and apoptosis (metallothionein). When comparing with similar proteomic studies by Singh et al, all modulation effects identified by L. aethiopica and L. mexicana were not previously shown during L. donovani infection. Infection was tested against human T lymphocytes as they have been implicated in the production of cytokines for the activation of macrophages allowing the elimination of intracellular parasites within macrophages. This novel work has shown L. aethiopica and L. mexicana are capable of infecting Jurkat cells (N=3) and enriched human T lymphocytes extracted from five different individuals. This finding has uncovered that infection is not only includes T cells (including CD4+ subsets) but percentage of infection is dependant on the species of parasites and the donor lymphocytes. In conclusion, this research showed for the first time that L. aethiopica and L. mexicana modulate a repertoire of protein expression at 24hrs post infection. The changes of cytokines expression highlights differences between different species and the discovery that Leishmania has the ability to infect human T cells may commence the start of the complete understanding of the survival mechanisms imposed by the parasite on the wider cellular network. This will change the approach to studying immunology of leishmaniasis infection and potentially clarifying the role of these cells for which contrasting evidences in human and mice models have caused much debate.
- Published
- 2017
7. Ex Vivo Analysis of the Association of GFP-Expressing L. aethiopica and L. mexicana with Human Peripheral Blood-Derived (PBD) Leukocytes over 24 Hours.
- Author
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Ranatunga, Medhavi, Deacon, Andrew, Harbige, Laurence S., Dyer, Paul, Boateng, Joshua, and Getti, Giulia T. M.
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REGULATORY T cells ,B cells ,FIBROBLASTS ,LEUCOCYTES ,DENDRITIC cells ,T cells - Abstract
Leishmania parasites are transmitted to mammalian hosts through the bite of sandflies. These parasites can infect phagocytic cells (macrophages, dendritic cells, and neutrophils) and non-phagocytic cells (B cells and fibroblasts). In mice models, the disease development or resolution is linked to T cell responses involving inflammatory cytokines and the activation of macrophages with the M1/M2 phenotype. However, this mechanism does not apply to human infection where a more complex immunological response occurs. The understanding of interactions between immune cells during Leishmania infection in humans is still limited, as current infection models focus on individual cell types or late infection using controlled human infection models (CHIMs). This study investigated the early parasite infection in freshly isolated peripheral blood-derived (PBD) leukocytes over 24 h. Flow cytometer analysis is used in immunophenotyping to identify different subpopulations. The study found that among the L. aethiopica
GFP -associated leukocytes, most cells were neutrophils (55.87% ± 0.09 at 4 h) and monocytes (23.50% ± 0.05% at 24 h). B cells were 12.43% ± 0.10% at 24 h. Additionally, 10–20% of GFP+ leukocytes did not belong to the aforementioned cell types, and further investigation revealed their identity as CD4+ T cells. Data not only confirm previous findings of Leishmania infection with PBD leukocytes and association with B cells but also suggest that CD4+ T cells might influence the early-stage of infection. [ABSTRACT FROM AUTHOR]- Published
- 2024
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8. Oakland Takes Horizon League Semifinals 74-71 Against Cleveland State (Gallery)
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Deacon, Andrew
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News, opinion and commentary ,Sports and fitness - Abstract
Byline: Andrew Deacon .post-content__body { --ricos-text-color: #ffffff; --ricos-text-color-tuple: 255, 255, 255; --ricos-action-color: #ffffff; --ricos-action-color-tuple: 255, 255, 255; --ricos-background-color: #000000; --ricos-background-color-tuple: 0, 0, 0; --ricos-fallback-color: #000000; --ricos-fallback-color-tuple: 0, 0, 0; --ricos-action-color-fallback: [...]
- Published
- 2024
9. Designing for Learning through Multimodal Production: Film Narrative and Spectatorship in 'Director's Cut'
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Deacon, Andrew, Morrison, Andrew, and Stadler, Jane
- Abstract
We describe the evolving learning design of a computer-based exercise called "Director's Cut" that challenges students to create their own video sequence from a set of clips we provide. The context is a film theory course where the community of educators have been interested in introducing practical exercises so students can, for example, experience how their choices influence which character the audience identifies with most strongly. This design process is presented within the theoretical frames of multimodality and production based learning, offering insights into how we balanced constraints and creativity as learning designers in the context of a South African university
- Published
- 2005
10. A Walker-Writer of Dublin
- Author
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Deacon, Andrew
- Subjects
Intimate City: Dublin Essays (Essay collection) -- Sirr, Peter ,Books -- Book reviews ,Literature/writing - Abstract
THERE IS AN ESSAY in Peter Sirr's collection Intimate City which describes his looking in the window of an old favorite bookshop, Greene's of Clare Street, Dublin, and finding it [...]
- Published
- 2023
11. MOOC-Making and Open Educational Practices
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Czerniewicz, Laura, Deacon, Andrew, Glover, Michael, and Walji, Sukaina
- Abstract
MOOCs have been seen as holding promise for advancing Open Education. While the pedagogical design of the first MOOCs grew out of the Open Education Movement, the current trend has MOOCs exhibiting fewer of the original openness goals than anticipated. The aim of this study is to examine the practices and attitudes of MOOC educators at an African university and ask whether and how their practices and attitudes become open after creating and teaching a MOOC. Activity Theory is used to contextually locate the educators' motivations and to analyse their practices in terms of striving towards an object. With this lens we describe how educators' openness-related practices and attitudes change over time in two different MOOCs. Two sets of conceptions of open practices are used to detect instances of change, providing four dimensions of changed open educational practices. Semi-structured interviews, focus groups, and artefacts provide data for this rare study, which considers these issues from the perspective of the Global South. Through studying the educators' practices in relation to openness, it becomes evident how open practices are emergent and responsive.
- Published
- 2017
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12. An update on the management of patients with rib fractures
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Lumley, Andrew, Chan, Sean, and Deacon, Andrew
- Published
- 2019
13. Preventing vascular damage during central venous catheter insertion via the internal jugular vein
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Bath, Jennifer, Deacon, Andrew, and Jones, Alister
- Published
- 2019
14. Measurement of pulse oximetry, capnography and pH
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Deacon, Andrew J. and Pratt, Oliver W.
- Published
- 2017
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15. Lil Yachty Takes the Field Trip Tour to Detroit
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Deacon, Andrew
- Subjects
Rap singers ,News, opinion and commentary ,Sports and fitness - Abstract
Byline: Andrew Deacon Atlanta rapper Lil Yachty brought the Field Trip Tour to The Fillmore on Sunday night for the 23rd stop of The Field Trip Tour. Lil Yachty performs [...]
- Published
- 2023
16. DJ Spotlight: DJ Katz
- Author
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Deacon, Andrew
- Subjects
News, opinion and commentary ,Sports and fitness - Abstract
Byline: Andrew Deacon Meet Nathan Katzenberger (AKA DJ Katz), host of Under the Radar which broadcasts weekly on Thursdays at 3pm. What is your name? Nathan Katzenberger What is your [...]
- Published
- 2023
17. WXOU's Fall Essentials
- Author
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Deacon, Andrew
- Subjects
News, opinion and commentary ,Sports and fitness - Abstract
Byline: Andrew Deacon We asked the students of OU to give us their best fall songs. Enjoy this playlist, hand-picked just for you to help prevent the seasonal depression from [...]
- Published
- 2023
18. Learning through Engagement: MOOCS as an Emergent Form of Provision
- Author
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Walji, Sukaina, Deacon, Andrew, Small, Janet, and Czerniewicz, Laura
- Abstract
Massive open online courses (MOOCs) are a new form of educational provision occupying a space between formal online courses and informal learning. Adopting measures used with formal online courses to assess the outcomes of MOOCs is often not informative because the context is very different. The particular affordances of MOOCs shaping learning environments comprise scale (in terms of numbers of students) and diversity (in terms of the types of students). As learning designers, we focus on understanding the particular tools and pedagogical affordances of the MOOC platform to support learner engagement. Drawing on research into learner engagement conducted in the broader field of online learning, we consider how learner engagement in a MOOC might be designed for by looking at three pedagogical aspects: teacher presence, social learning, and peer learning.
- Published
- 2016
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19. What is the role of thoracic epidural analgesia in contemporary anaesthesia practice?
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Deacon, Andrew and Hartley, Jennifer
- Published
- 2017
20. No Comfort Zone from Eoghan Smith
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Deacon, Andrew
- Subjects
A Provincial Death (Novel) -- Smith, Eoghan ,Books -- Book reviews ,Literature/writing - Abstract
EOGHAN SMITH'S first novel The Failing Heart was a welcome breath of stale air in the world of the Irish novel. It concerned itself not with the materialism of post-Catholic [...]
- Published
- 2022
21. Chapter 27 - Chronic Pulmonary Disease
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Deacon, Andrew J. and Slinger, Peter D.
- Published
- 2023
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22. Learning as Acquiring a Discursive Identity through Participation in a Community: Improving Student Learning in Engineering Education
- Author
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Allie, Saalih, Armien, Mogamat Noor, Burgoyne, Nicolette, Case, Jennifer M., Collier-Reed, Brandon I., Craig, Tracy S., Deacon, Andrew, Fraser, Duncan M., Geyer, Zulpha, Jacobs, Cecilia, Jawitz, Jeff, Kloot, Bruce, Kotta, Linda, Langdon, Genevieve, le Roux, Kate, Marshall, Delia, Mogashana, Disaapele, Shaw, Corrinne, Sheridan, Gillian, and Wolmarans, Nicolette
- Abstract
In this paper we propose that learning in engineering involves taking on the discourse of an engineering community, which is intimately bound up with the identity of being a member of that community. This leads to the notion of discursive identity, which emphasises that students' identities are constituted through engaging in discourse. This view of learning implies that success in engineering studies needs to be defined with particular reference to the sorts of identities that students develop and how these relate to identities in the world of work. In order to achieve successful learning in engineering we need to recognise the multiple identities held by our students, provide an authentic range of engineering-related activities through which students can develop engineering identities and make more explicit key aspects of the discourse of engineering of which lecturers are tacitly aware. We include three vignettes to illustrate how some of the authors of this paper (from across three different institutions) have applied this perspective of learning in their teaching practice.
- Published
- 2010
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23. Learning as Acquiring a Discursive Identity through Participation in a Community: Improving Student Learning in Engineering Education
- Author
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Allie, Saalih, Armien, Mogamat Noor, Burgoyne, Nicolette, Case, Jennifer M., Collier-Reed, Brandon I., Craig, Tracy S., Deacon, Andrew, Fraser, Duncan M., Geyer, Zulpha, Jacobs, Cecilia, Jawitz, Jeff, Kloot, Bruce, Kotta, Linda, Langdon, Genevieve, le Roux, Kate, Marshall, Delia, Mogashana, Disaapele, Shaw, Corrinne, Sheridan, Gillian, and Wolmarans, Nicolette
- Abstract
In this paper, we propose that learning in engineering involves taking on the discourse of an engineering community, which is intimately bound up with the identity of being a member of that community. This leads to the notion of discursive identity, which emphasises that students' identities are constituted through engaging in discourse. This view of learning implies that success in engineering studies needs to be defined with particular reference to the sorts of identities that students develop and how these relate to identities in the world of work. In order to achieve successful learning in engineering, we need to recognise the multiple identities held by our students, provide an authentic range of engineering-related activities through which students can develop engineering identities and make more explicit key aspects of the discourse of engineering of which lecturers are tacitly aware. We include three vignettes to illustrate how some of the authors of this paper (from across three different institutions) have applied this perspective of learning in their teaching practice.
- Published
- 2009
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24. Student Experience Survey report - 2022
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Gachago, Daniela, Deacon, Andrew, and Walji, Sukaina
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student experience survey ,student satisfaction survey ,RETL - Abstract
The UCT student experience survey explored UCT students’ satisfaction with teaching and learning in Semester 1 of 2022. The survey ran between Semesters 1 and 2, with 720 completed responses received, representing a response rate of approximately 2.5%. The survey was conducted in response to students expressing dissatisfaction with their experiences studying at the university. The Semester 1 of 2022 represented a period during which teaching was partly returning to campus following the pandemic. Overall, 66% of students reported being satisfied with the quality of their teaching and learning experience, with 19% neutral and 16% dissatisfied. The experiences reported varied across groups of students and aspects of teaching and learning. First-year students expressed higher levels of satisfaction than other undergraduates. Also, postgraduate students and students living at home or private residences were more vocal about blended learning than others. Given the findings of the survey, it is evident that although a majority of students do look forward to coming back to campus, there are subsets of students who will miss the flexibility blended learning offers.
- Published
- 2022
25. Customising Microsoft Office to Develop a Tutorial Learning Environment
- Author
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Deacon, Andrew, Jaftha, Jacob, and Horwitz, David
- Abstract
Powerful applications such as Microsoft Office's Excel and Word are widely used to perform common tasks in the workplace and in education. Scripting within these applications allows unanticipated user requirements to be addressed. We show that such extensibility, intended to support office automation-type applications, is well suited to the creation of learning activities and learning environments. We have developed a range of tutorial activities using Excel and Word in introductory mathematics, writing and economics courses. These tutorials have the dual purpose of teaching academic concepts and practical computer literacy skills. The software architecture of our learning environment includes a database-supported back-end to automatically record students responses, which allows for greater control over what students do. Additionally, this allows one to automate common procedures to improve usability and feedback automation to support learning. We have been applying our ideas for the last six years and currently 1,500 students are using the environment. We suggest that this pragmatic solution can provide a high degree of interactivity and flexibility in a range of learning contexts that represents a cost-effective alternative for use alongside traditional approaches.
- Published
- 2004
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26. Media Rich, Resource Poor: Practical Work in an Impractical Environment
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van der Vliet, Emma and Deacon, Andrew
- Abstract
Film and media courses appear well placed to exploit technology convergence in exposing students both to practical skills and to theoretical concepts. For the University of Cape Town's (UCT) large film and media studies courses, it is impractical simply to use the technology of professionals as this would typically be too expensive to purchase and time-consuming to run. Our approach has been to develop activities that can run with large classes in generic computer laboratories and which simulate environments and tools of the real world. Two illustrative examples, emphasising writing skills in context, involve the production of a TV news story and the development of a proposal for an educational soap opera. Using these, we reflect on our experience of integrating practical skills into the curriculum of a traditional academic institution, where these skills have a lower status and must be sufficiently flexible to accommodate changes in the higher-status academic components. This suggests that such flexibility has to be part of the design of practical interventions and that they should additionally aim to provide a challenge to some of the more theoretical aspects of these courses. While developing one's own interventions allows for some of this flexibility to be incorporated into the design, it remains difficult for academic departments to adopt these solutions as their own, thus requiring continued involvement of the original developers to adapt to changes.
- Published
- 2004
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27. Announcing the Newly Redesigned WXOU Website
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Deacon, Andrew
- Subjects
Web sites ,Company Web site/Web page ,News, opinion and commentary ,Sports and fitness - Abstract
Byline: Andrew Deacon After more than two years of little to no updates, the old wxou.org website has had a slick new redesign thanks to the work of the 2022 [...]
- Published
- 2022
28. Seizing opportunities: MOOC takers making time for change
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Deacon, Andrew, Walji, Sukaina, Jawitz, Jeff, Small, Janet, and Jaffer, Tasneem
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flexibility, MOOCs, online learning, temporalities, time ,lcsh:L7-991 ,lcsh:Education (General) - Abstract
We interviewed people living in African countries who have taken Massive Open Online Courses (MOOCs) created by the University of Cape Town to ask about their challenges, goals, and value studying online. They are drawn to taking MOOCs in part because of the claims around flexible learning opportunities for people with busy lives. A striking feature in these interviews is the many references to the challenges associated with negotiating time to study online. Here we wish to move beyond simply identifying deficit models of time or time management and rather seek to understand the value of MOOCs to people with work or career transition goals. The MOOC takers’ experiences are quite different to those in conventional degree courses as MOOC participation is voluntary and must be negotiated around existing commitments, suggesting a need for reframing of what is valued by people studying online in their own time.Keywords: flexibility, MOOCs, online learning, temporalities, time
- Published
- 2019
29. Inflation-indexed Securities: Bonds, Swaps and Other Derivatives
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Mark Deacon, Andrew Derry, Dariush Mirfendereski
- Published
- 2004
30. Designing protected areas to conserve riverine biodiversity: Lessons from a hypothetical redesign of the Kruger National Park
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Roux, Dirk J., Nel, Jeanne L., Ashton, Peter J., Deacon, Andrew R., de Moor, Ferdinand C., Hardwick, Devlyn, Hill, Liesl, Kleynhans, Cornelius J., Maree, Gillian A., Moolman, Juanita, and Scholes, Robert J.
- Published
- 2008
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31. A COMMODITY TO BE EXPLOITED AND EXHAUSTED: EXPRESSIONS OF ALIENATION IN HIGHER EDUCATION.
- Author
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Gachago, Daniela, Cheng-Wen Huang, Czerniewicz, Laura, and Deacon, Andrew
- Subjects
MENTAL health ,HIGHER education - Abstract
There are concerns about mental health in academia globally, which is a direct consequence of an increase of a neoliberal entrepreneurial approach, one heightened during the time of the pandemic. This paper uses Skotnicki and Nielsen's categories of alienation and Fisher's work on capitalist realism to make sense of academic staff's responses to a survey on their experiences with Emergency Remote Teaching, collected in 2021 at a large research-intensive university in South Africa. The responses indicate that participants all experienced some form of alienation, though experienced and expressed differently. We suggest expanding Skotnicki and Nielsen's lens on agency and structure with what we found missing, an element of culture, to ask the question: "How can a university create and rebuild a sense of community and belonging to counter alienation?". We propose a concerted effort to build spaces for collective encounters to rediscover community, which may allow us to re-imagine a future for the academy beyond conflicting imperatives of responding to the need for socio-economic redress and delivering education as a public good, in times of austerity budgets. [ABSTRACT FROM AUTHOR]
- Published
- 2022
32. UCT ERT Student Experience Survey 2020
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Marquard, Stephen, Walji, Sukaina, Lester, Soraya, Kefale, Kende, Deacon, Andrew, CILT, and Centre for Higher Education Development
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Emergency Remote Teaching ,Student Experience ,ComputingMilieux_COMPUTERSANDEDUCATION ,COVID-19 ,Education - Abstract
Final report of the UCT Emergency Remote Teaching Student Experience Survey 2020, an online survey of student experiences of emergency remote teaching (ERT) during the 2nd term of 2020 (April to July 2020). The purpose of the survey was to inform and improve the design of courses taught online during the second semester of 2020 (August to November), and improve support for students where possible. The survey was thus a form of institutional research and followed an exploratory research design rather than setting out to confirm or disprove specific hypotheses. The report presents key concerns of students during this time period, including mental health, course workload in relation to available time, and challenges relating to course site design, assessments, social connectedness, Internet access and mobile data and preferences relating to video material and synchronous teaching. While most students experienced some difficulties arising from ERT and the COVID-19 lockdown conditions, students who no longer had access to UCT residences after the start of ERT were particularly adversely affected.
- Published
- 2020
33. Leishmania aethiopica cell‐to‐cell spreading involves caspase‐3, AkT, and NF‐κB but not PKC‐δ activation and involves uptake of LAMP‐1‐positive bodies containing parasites
- Author
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Ranatunga, Medhavi, Rai, Rajeev, Richardson, Simon C. W., Dyer, Paul D. R., Harbige, Laurence, Deacon, Andrew, Pecorino, Lauren, and Getti, Giulia T. M.
- Subjects
parasitic diseases - Abstract
Development of human leishmaniasis is dependent on the ability of intracellular Leishmania parasites to spread and enter macrophages. The mechanism through which free promastigotes and amastigotes bind and enter host macrophages has been previously investigated; however, little is known about intracellular trafficking and cell-to-cell spreading. In this study, the mechanism involved in the spreading of Leishmania aethiopica and Leishmania mexicana was investigated. A significant increase in phosphatidylserine (PS) exhibition, cytochrome C release, and active caspase-3 expression was detected (P
- Published
- 2020
34. Weathering wikis: Net-based learning meets political science in a South African university
- Author
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Carr, Tony, Morrison, Andrew, Cox, Glenda, and Deacon, Andrew
- Published
- 2007
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35. Contributors
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Abdelmalak, Basem B., Abrecht, Christopher R., Adams, Meredith C.B., Agrawal, Ashish, Andropoulos, Dean B., Berde, Charles B., Berenstain, Laura, Blitz, Jeanna D., Bokoch, Michael P., Borgmeier, Emilee, Bouez, Joanna, Braehler, Matthias R., Breyer, Kristine E.W., Brull, Richard, Chang, Joyce, Chernin, Tyler Seth, Chiu, Catherine, Chung, Frances, Cil, Hemra, Cohen, Neal H., Columbano, Heather A., Cook, Daniel Charles, Cui, Wilson, Davis, Ryan Paul, Deacon, Andrew J., Donovan, Anne L., Egan, Talmage D., Feiner, John, Flexman, Alana, Furgiuele, David, Gandhi, Seema, Gayer, Steven, Gebauer, Sarah, Glick, David B., Gottlieb, Erin A., Gray, Andrew T., Hemmings, Hugh C., Jr., Hewson, David W., Huddleston, Lindsey L., Hurley, Robert W., Infosino, Andrew, Johnson, Ken B., Kim, Tae Kyun, Koka, Anjali, Lancman, Benn, Lee, Chanhung Z., Legrand, Matthieu, Lien, Cynthia A., Lilaonitkul, Maytinee, Liu, Linda L., Macfarlane, Alan J.R., Malhotra, Vinod, Manuel, Solmaz Poorsattar, Marshall, Mitchell H., McCann, Mary Ellen, McCarthy, Grace C., McEvoy, Matthew D., Meng, Lingzhong, Miller, Ronald D., Mizrahi, Ilan, Obara, Shinju, Palte, Howard D., Pamnani, Anup, Panigrahi, Anil K., Pardo, Manuel C., Jr., Poorsattar, Sophia P., Rollins, Mark D., Rosenberg, Andrew D., Shah, Ann Cai, Shimabukuro, David, Singh, Mandeep, Sinskey, Jina, Slinger, Peter D., Smith, Wendy, Soriano, Sulpicio G., Steadman, Randolph H., Stein, Erica J., Steurer, Marc P., Su, Po-Yi Paul, Sullivan, Kristina R., Thompson, Annemarie, Toda, Chihiro, Tremper, Kevin K., Tung, Avery, Warrick, Christine M., Weston, Stephen D., Xia, Victor W., and Yap, Edward N.
- Published
- 2023
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36. Notes on the induced reproduction and development of the tigerfish,Hydrocynus vittatus (Characidae), embryos and larvae
- Author
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Steyn, Gert J., Gagiano, Christo L., Deacon, Andrew R., and du Preez, Hein H.
- Published
- 1996
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37. Chapter 27 - Chronic Pulmonary Disease and Thoracic Anesthesia
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Deacon, Andrew J. and Slinger, Peter D.
- Published
- 2018
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38. Management of chronic obstructive pulmonary disease.
- Author
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Katzenberg, Gideon, Deacon, Andrew, Aigbirior, Joshua, and Vestbo, Jørgen
- Abstract
Chronic obstructive pulmonary disease is a prevalent condition in the UK, associated with high morbidity and mortality. Hospital physicians manage a significant portion of acute chronic obstructive pulmonary disease admissions to hospital and readmissions after discharge. Optimal management of exacerbations requires controlled oxygen therapy and ventilatory support where necessary, and careful administration of bronchodilators, steroids and antibiotics. Holistic care for these patients includes nutritional supplementation and palliative support for those with advanced disease. To reduce the chance of readmission, chronic obstructive pulmonary disease care bundles can be used, along with a review of inhaled and oral therapies. Where available, hospital-at-home discharge schemes can safely facilitate early discharge. Most importantly, high quality evidence-based smoking cessation support must be offered to smokers. Exercise improves the physiological and psychological condition of people with chronic obstructive pulmonary disease and should be encouraged, with referral to a pulmonary rehabilitation service if available. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
39. OER in and as MOOCs
- Author
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Czerniewicz, Laura, Deacon, Andrew, Walji, Sukaina, and Glover, Michael
- Subjects
pedagogy ,open practices ,OER Education ,Global South ,MOOC ,South Africa ,learner-centred ,Open Educational Resources ,OEP ,Massive Open Online Courses (MOOCs) ,University of Cape Town ,OER ,Open Educational Practices ,ROER4D - Abstract
This chapter reports on the investigation into the production and rollout of four Massive Open Online Courses (MOOCs) at the University of Cape Town (UCT) in South Africa, and on the experiences of the educators involved in their production. The overarching aim of this study is to address the question: How does MOOC-making with Open Educational Resources (OER) influence educators’ Open Educational Practices (OEP)? The authors were interested to know why UCT educators wanted to make MOOCs, whether they adopted OER, whether their practices become more open after making a MOOC, and in which ways. Drawing on Beetham et al. (2012) and Hodgkinson-Williams (2014), an analytic framework of OEP was developed comprising three dimensions: legal, pedagogical and financial. The research methodology is qualitative, using semi-structured interviews and data from MOOC discussion forums. Six MOOC lead educators were interviewed at three intervals: before their MOOCs ran, immediately after their MOOC’s first run, and six to 10 months later. Transcripts were coded using OEP concepts. The findings offer insights into the relationships between educators’ motivations for making MOOCs, their MOOC design tools, the OEP that can be identified and the contradictions they experienced in making MOOCs. Despite the challenges that educators faced, they largely achieved their purposes of making MOOCs and manifested legal, pedagogical and financial dimensions of OEP. The impact on educators’ open practices was observed in several subsequent projects after the MOOCs were first run. Tensions involved in making MOOCs, adopting OER and enacting OEP point to how educators could be better supported to become more open in their educational practices. No negative experiences were attributed to the creation of OER and, indeed, MOOC-making with OER appeared to be conducive to OER adoption in general. However, more time would be needed to conclude whether these educators could become OER advocates or could function autonomously in creating and sharing OER. The dataset arising from this study can be accessed at: https://www.datafirst.uct.ac.za/dataportal/index.php/catalog/600
- Published
- 2017
- Full Text
- View/download PDF
40. MOOCs, openness and changing educator practices: an Activity Theory case study
- Author
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Czerniewicz, Laura, Glover, Michael, Deacon, Andrew, and Walji, Sukaina
- Subjects
openness ,open educational resources ,MOOCs ,Activity Theory ,ComputingMilieux_COMPUTERSANDEDUCATION ,OER ,open education ,Higher education - Abstract
The practices and perceptions of educators formed through the creation and running of a Massive Open Online Course (MOOC) provide a case study of how educators understandings of ‘openness’ change (Beetham et al 2012, p 3). We are interested in how educators engage with open education resources (OER) and openness as part of developing open online courses, and how this informs their practices and attitudes afterwards. Deepening understandings of these changes is important for informing strategies involving helping educators in adopting productive open educational practices. Our research question is how do educators’ practices change or not change when using - or not using - OER in and as a MOOC? We are interested in whether and why educators adopt open practices in their MOOCs. We employ an Activity Theory (AT) conceptual framework as a heuristic tool to track and thickly describe educators’ practices and perceptions. This frame enables us to locate educators’ practices - in a context of mediating nodes, i.e., tools/artefacts, rules, divisions of labour, and community – as they strive towards and consider their object. The object upon which the educators act is the development of a new interdisciplinary field. We focus on the role of two mediating artefacts introduced into the activity system, namely Creative Commons (CC) licenses and the ‘MOOC design’. We describe how the open aspect of these artefacts mediate and affect educator’s perceptions, attitudes and educational practices in the context of their object-directed activity system. We draw predominantly on semi-structured interviews with the MOOC lead educators and the MOOC learning designers. Interviews were conducted at two time intervals, before and after the MOOC has run. From this we craft two activity systems. We have categorised our findings according to Beetham et al’s dimensions of open practices. Further, two broad themes emerged from the data analysis. These are Affordances of the MOOC and Reflection on educational practices.
- Published
- 2016
41. Understanding How Participants Use Open Online Courses for Transitions.
- Author
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Walji, Sukaina, Deacon, Andrew, Jawitz, Jeff, Small, Janet, and Jaffer, Tasneem
- Subjects
MASSIVE open online courses ,DISTANCE education ,CURRICULUM ,CLASSROOM environment ,EDUCATIONAL technology ,VIRTUAL classrooms - Abstract
Massive Open Online Courses (MOOCs) are created with a broad audience and learning purpose in mind, and informal feedback has shown that they have been used by people making transitions. From the twelve MOOCs we created, we have seen cases of how participants valued the learning that is very different to a traditional formal education trajectory. Understanding and supporting transition pathways - in and out of learning and work - is increasingly important for universities aiming to, for example support working adults in ongoing professional development. Our research explores experiences of participants from African countries taking MOOCs offered by the University of Cape Town (UCT). In 2017, a pilot survey and interviews were conducted of people taking three UCT MOOCs. The interviews were conducted with a sample of learners living in Africa. We categorised the kinds of value participants report from taking open online courses, and consider how our categorisation relates to how transitions are often framed. Current framings of transitions in the research literature has emphasised school leaving youth entering higher education, while our interest is probing the needs of adults looking for flexible online learning opportunities. From the pilot interviews, we see innovative uses of open online courses for making life changes - such as preparing for postgraduate study, changing field within the workplace and discipline crossing to studying in new fields. Framing of transitions helps illuminate how these participants value open online courses for their own personal and professional development, to acquire skills and knowledge and to support their pathways in and out of learning and work. [ABSTRACT FROM AUTHOR]
- Published
- 2018
42. Wrapping of a Social Innovation MOOC.
- Author
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Deacon, Andrew, Jaffer, Tasneem, Jawitz, Jeff, Small, Janet, and Walji, Sukaina
- Subjects
MASSIVE open online courses ,DISTANCE education ,CURRICULUM ,EDUCATIONAL technology ,EDUCATIONAL innovations - Abstract
Massive Open Online Courses (MOOCs) have created opportunities for other educators to reuse them in their own courses. In this study we investigate various forms in which the 'Becoming a changemaker: Introduction to Social Innovation' MOOC has come to be reused in other courses. This MOOC is based on an existing Masters course and intended to develop ways of thinking about the complexities of social change beyond the university. The academic department uses the MOOC materials to support its own teaching. Educators might ask their on-campus students to participate partially or fully in a MOOC and supplement this online learning experience with classroom activities. Outside the university other educators may support an in-person facilitated MOOC encounter to ameliorate connectivity and bandwidth constraints. These approaches are often referred to as "wrapping a MOOC". In this study we interviewed five educators who have been wrapping this UCT MOOC, both within and outside the university. From the literature and analysis of the interview data we develop a characterisation of the different forms of wrapping and their intended purposes. The clear differences between wrapping inside and outside the university context reflected how the MOOC curriculum design was interpreted, with a wider interpretation and a localisation of the curriculum outside the university. Wrapping also offers insights to how MOOC initiatives are being recognised and valued by others. [ABSTRACT FROM AUTHOR]
- Published
- 2018
43. A Kumeyaay's Reflection.
- Author
-
Orosco, Deacon Andrew (Andy)
- Abstract
The article focuses on reflections about the 250th anniversary we are commemorating throughout 2019 and how it has helped me to listen, understand to citizens of San Diego, California. It mentions abject poverty on reservations and negative stereotypes and reservations were created, government officials often selected lands that were remote and not coveted by white settlers. It also mentions unique struggles and successes that demonstrate the strength, courage, and resilience of native peoples.
- Published
- 2019
44. Position Paper: MOOCs
- Author
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Czerniewicz, Laura, Deacon, Andrew, Fife, Mary-Ann, Small, Janet, and Walji, Sukaina
- Subjects
higher education ,online learning ,ComputingMilieux_COMPUTERSANDEDUCATION ,curriculum ,MOOC ,blended learning - Abstract
Massive open online courses (MOOCs) are a flexible and open form of self-directed, online learning designed for mass participation. There are no fees or entry requirements and no formal academic credit is available. While completion rates are low (on average ten per cent) due to varying motivations for enrolling in a MOOC, absolute numbers of participants who complete are usually high. While access to the course material is free, MOOC platform providers often offer certificates of completion at a cost. MOOC platforms provide institutions with cloud-based hosting environments for delivering courses, offering scale and functionality while the institution provides the course material and reputational value. This paper discusses the key aspects of Massive Open Online Courses in a South African educational context.
- Published
- 2015
45. Pedagogic strategies to support learning design thinking in a masters course
- Author
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Hodgkinson-Williams, Cheryl, Deacon, Andrew, Dean's Office: CHED, and Centre for Higher Education Development
- Subjects
pedagogic strategies ,design thinking ,ComputingMilieux_COMPUTERSANDEDUCATION ,educational technology - Abstract
The demand for further skills and qualifications in the educational technology field remains strong as the range of technologies increases and their potential use in educational contexts becomes more compelling. Students registering for the University of Cape Town (UCT) Masters level courses are employed in schools, government agencies, universities, non-governmental organisations, or in the corporate sector, where their role in designing educational technology interventions represents part of their responsibilities. Because they have varying levels of experience in designing educational materials and/or using educational technologies, they need to develop learning design thinking and gain practice with a broad range of pedagogic strategies, theories, and technology tools to be productive in the workplace. Over the past four years we have developed and adopted a course for the needs of people who are keen to apply these skills in their work contexts. We describe here, the pedagogic strategies we explicitly adopted to model and support learning design thinking in one of four modules, Online Learning Design. The module adopts a learning design framework developed by Dabbagh and Bannan- Ritland (2005) to introduce students to design processes, and uses the same framework as a loose structure for the module and assignments. We apply Dabbagh and Bannan- Ritland's classification of pedagogic strategies to model and analyse approaches to cultivating learning design thinking amongst the students. As an analytic advice, we draw on Engeström's (2001) Activity Theory to describe the evolving learning context and our changing pedagogic strategies over four years. We focus on key tensions that emerged from the adoption of a range of pedagogic strategies to cultivate the students' learning design thinking when developing learning activities to communicate complex design issues. The key social change highlighted in this paper is that educational technology educators aiming to cultivate students' learning design thinking, need to apply their design thinking to their own practice.
- Published
- 2013
46. Contributors
- Author
-
Abouleish, Amr E., Adams, Meredith C.B., Andropoulos, Dean B., Apfelbaum, Jeffrey L., Barnett, Sheila R., Berde, Charles B., Bokoch, Michael P., Breyer, Kristine E.W., Brull, Richard, Chan, Vincent W.S., Chang, Tony, Chung, Frances, Cohen, Neal H., Cole, Daniel J., Cui, Wilson, Deacon, Andrew J., Dickerson, David M., Domino, Karen B., Drasner, Kenneth, Egan, Talmage D., Eilers, Helge, Feiner, John, Flexman, Alana, Frost, Elizabeth A.M., Furman, William R., Gayer, Steven, Gebauer, Sarah, Gerlach, Rebecca M., Glick, David B., Gottlieb, Erin A., Gray, Andrew T., Haehn, Melissa, Huang, Jin J., Huddleston, Lindsey L., Hurley, Robert W., Hyder, Omar, Infosino, Andrew, Johnson, Ken B., Kim, Tae Kyun, Klinger, Kerry, Koka, Anjali, Kuza, Catherine, Lancman, Benn, Lee, Chanhung Z., Liu, Linda L., Lucero, Jennifer M., Macfarlane, Alan J.R., Malhotra, Vinod, Marshall, Mitchell H., McCann, Mary Ellen, McIsaac, Joseph H., III, McKay, Rachel Eshima, Meng, Lingzhong, Miller, Ronald D., Newberry, Cynthia, Nicholau, Dorre, Obara, Shinju, Palte, Howard D., Pamnani, Anup, Pardo, Manuel C., Jr., Parekh, Krishna, Rathmell, James P., Robertson, Amy C., Robinowitz, David, Rollins, Mark D., Rosenberg, Andrew D., Roth, Patricia, Schulman, Scott R., Shimabukuro, David, Singh, Mandeep, Slinger, Peter D., Soriano, Sulpicio G., II, Springman, Scott, Steadman, Randolph H., Stein, Erica J., Steurer, Marc, Sweitzer, Bobbie Jean, Szocik, James, Teig, Magnus, Tremper, Kevin K., Tung, Avery, Turnbull, John H., Wallace, Arthur, Weston, Stephen D., Whitlock, Elizabeth L., Xia, Victor W., and Yap, Edward N.
- Published
- 2018
- Full Text
- View/download PDF
47. Learning from the rhetoric of academics using educational technology
- Author
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Deacon, Andrew, Wynsculley, Cathrine, CILT, and Centre for Higher Education Development
- Abstract
Seminar presentations, by academics successfully using educational technology to support their courses, form a visible part of many staff development programmes. These events contribute to developing a community of academics that use educational technology and are sharing experiences on its use in supporting teaching and learning. We draw on classic rhetorical analysis to highlight the epideictic or ceremonial form of these presentations we see as exemplary of these events. These presentations tend to be quite distinct from how educational technology research or best practice is disseminated. We argue that this epideictic form is a vital component in emerging communities of practice and, for example, communicates the value of working collaboratively. While the underlying intuition is widely acknowledged, our analysis offers a framework to view these conscious and stylistic choices across learning communities.
- Published
- 2007
48. How Are Priests Trained? A look at the Church's program to form seminarians.
- Author
-
Clyne, Deacon Andrew
- Subjects
- *
PRIESTS , *CATHOLIC theological seminaries , *RELIGIOUS institutions ,COUNCIL of Trent (1545-1563) - Abstract
The article focuses on the history of priestly formation in the Catholic Church, with the development of Council of Trent (1545-1563), in its Twenty-Third Session. It mentions that it is the period when the council fathers had the framework for the establishment of seminaries as permanent institutions for the training of clerics.
- Published
- 2017
49. The Horrors of John Carpenter's Halloween.
- Author
-
Deacon, Andrew
- Subjects
HORROR films ,FILM genres ,MOTION picture plots & themes - Abstract
The article analyzes the film "Halloween," by John Carpenter. It states that the film was regarded as a classic of the horror genre, and it explores the story of the movie to help contextualize the discussion. The author mentions the simplicity of the narrative that permitted Carpenter to focus on other aspects of the movie, and making it a skillfully create horror.
- Published
- 2015
- Full Text
- View/download PDF
50. A study of graduate students in an astrophysics bridging year: Identifying contradictions in a complex system.
- Author
-
Nwosu, Victoria, Allie, Saalih, Demaree, Dedra, and Deacon, Andrew
- Subjects
ASTROPHYSICS ,SPACE sciences ,GRADUATE students ,ACADEMIC achievement ,GRADUATE education ,SYSTEM identification - Abstract
Black South African students who transfer from 'Historically Black Universities' to the National Graduate Program in Astrophysics and Space Science at the University of Cape Town often struggle academically. While our previous studies focused on student epistemology and went some way towards understanding student under-performance it became clear that broader socio-cultural and systemic issues were playing critical roles. Using Cultural Historical Activity Theory (CHAT) as a theoretical perspective we (a) characterized the broader context as an Activity System and (b) identified the four main types of systemic contradictions as proposed by the theory. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
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