1. Hyperfluorescence associated with serous retinal pigment epithelial detachment on indocyanine green angiography
- Author
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Sandro Fachin, Maurizio Battaglia Parodi, Paolo Panetta, Giuseppe Ravalico, Elvio Bondel, Sandro Saviano, D. Iustulin, Saviano S, Saviano, S, Battaglia Parodi, M, Bondel, E, Panetta, P, Iustulin, D, Fachin, S, Ravalico, G, Ravalico, G., BATTAGLIA PARODI, M, and Ravalico, Giuseppe
- Subjects
Indocyanine Green ,medicine.medical_specialty ,Visual acuity ,medicine.medical_treatment ,Visual Acuity ,Fluorescence ,Macular Degeneration ,chemistry.chemical_compound ,Ophthalmology ,Humans ,Medicine ,Prospective Studies ,Fluorescein Angiography ,Pigment Epithelium of Eye ,Aged ,Aged, 80 and over ,Laser Coagulation ,medicine.diagnostic_test ,business.industry ,Retinal Detachment ,Retinal detachment ,Middle Aged ,Macular degeneration ,medicine.disease ,Fluorescein angiography ,Choroidal Neovascularization ,eye diseases ,Surgery ,Serous fluid ,Choroidal neovascularization ,chemistry ,sense organs ,medicine.symptom ,business ,Indocyanine green ,Laser coagulation - Abstract
Purpose: Indocyanine green angiography has been reported to improve detection and delineation of occult choroidal neovascularisation in serous pigment epithelium detachment in age-related macular degeneration. The study aims to evaluate the visual acuity results of eyes affected by serous pigment epithelium detachment in age-related macular degeneration, having had indocyanine green-directed laser photocoagulation, and to correlate them to the pattern of serous pigment epithelium detachment on indocyanine green angiography. Methods: Thirty-four eyes of 31 patients affected by serous pigment epithelium detachment in age-related macular degeneration were prospectively considered. Each patient underwent an ophthalmological examination including fluorescein and indocyanine green angiography one day before, and 6 weeks, 3 months, 6 months, 9 months, 12 months and 24 months after krypton-laser treatment. The serous pigment epithelium detachment was classified in the late-phases angiograms as either hypofluorescent, isofluorescent or hyperfluorescent comparing the fluorescence of the serous pigment epithelium detachment with the choroidal background fluorescence. Results: The indocyanine green-guided laser treatment was associated with a temporary stabilization and a long-term progressive reduction of visual acuity: after 24 months visual acuity improved in 2.9%, stabilized in 26.5% and worsened in 70.5% of cases. Serous pigment epithelium detachment presenting a pretreatment hyperfluorescence had a final visual acuity of 0.06, with subfoveal choroidal neovascularisation development in 100% of cases, whereas serous pigment epithelium detachment presenting a pretreatment hypofluorescence and isofluorescence showed a final visual acuity of 0.12, with subfoveal choroidal neovascularisation development in 43.5% of eyes, with statistically significant difference. Conclusion: Overall visual acuity decreases with time after indocyanine green-guided laser treatment of choroidal neovascularisation in serous pigment epithelium detachment, and serous pigment epithelium detachment becoming hyperfluorescent in the late-phases of indocyanine green angiography has the worst functional outcome.
- Published
- 1999