Author: "D. A. Lawlor" / Language: english - Searchworks@Jio Institute Digital Library Search Results

14 results on '"D. A. Lawlor"'

1. Maternal pre-pregnancy body mass index and risk of preterm birth: a collaboration using large routine health datasets

Author: R. P. Cornish, M. C. Magnus, S. K. Urhoj, G. Santorelli, L. G. Smithers, D. Odd, A. Fraser, S. E. Håberg, A. M. Nybo Andersen, K. Birnie, J. W. Lynch, K. Tilling, and D. A. Lawlor
Subjects: Body mass index, Maternal, Pre-pregnancy, Preterm birth, Non-linear, Parity, Medicine
Abstract: Abstract Background Preterm birth (PTB) is a leading cause of child morbidity and mortality. Evidence suggests an increased risk with both maternal underweight and obesity, with some studies suggesting underweight might be a greater factor in spontaneous PTB (SPTB) and that the relationship might vary by parity. Previous studies have largely explored established body mass index (BMI) categories. Our aim was to compare associations of maternal pre-pregnancy BMI with any PTB, SPTB and medically indicated PTB (MPTB) among nulliparous and parous women across populations with differing characteristics, and to identify the optimal BMI with lowest risk for these outcomes. Methods We used three UK datasets, two USA datasets and one each from South Australia, Norway and Denmark, together including just under 29 million pregnancies resulting in a live birth or stillbirth after 24 completed weeks gestation. Fractional polynomial multivariable logistic regression was used to examine the relationship of maternal BMI with any PTB, SPTB and MPTB, among nulliparous and parous women separately. The results were combined using a random effects meta-analysis. The estimated BMI at which risk was lowest was calculated via differentiation and a 95% confidence interval (CI) obtained using bootstrapping. Results We found non-linear associations between BMI and all three outcomes, across all datasets. The adjusted risk of any PTB and MPTB was elevated at both low and high BMIs, whereas the risk of SPTB was increased at lower levels of BMI but remained low or increased only slightly with higher BMI. In the meta-analysed data, the lowest risk of any PTB was at a BMI of 22.5 kg/m2 (95% CI 21.5, 23.5) among nulliparous women and 25.9 kg/m2 (95% CI 24.1, 31.7) among multiparous women, with values of 20.4 kg/m2 (20.0, 21.1) and 22.2 kg/m2 (21.1, 24.3), respectively, for MPTB; for SPTB, the risk remained roughly largely constant above a BMI of around 25–30 kg/m2 regardless of parity. Conclusions Consistency of findings across different populations, despite differences between them in terms of the time period covered, the BMI distribution, missing data and control for key confounders, suggests that severe under- and overweight may play a role in PTB risk.
Published: 2024
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2. Adventitial cystic disease of the common femoral artery

Author: Abdalla A. Butt, Farhad R. Udwadia, Gautamn Sarwal, and D. Kirk Lawlor
Subjects: Adventitial cystic disease, Claudication, Case report, Peripheral arterial disease, Surgical treatment, Diseases of the circulatory (Cardiovascular) system, RC666-701, Surgery, RD1-811
Abstract: Adventitial Cystic Disease (ACD) is a rare cause of peripheral arterial disease that accounts for less than 1% of all causes of claudication. It typically presents in younger individuals and surgical reconstruction is the mainstay of treatment. We report a case of a 60-year-old, active female with progressively worsening claudication, who presented with ultrasound and computed tomography angiography revealing ACD involving the common femoral artery. The patient underwent a complete resection of the affected artery, which was replaced with an interposition Dacron bypass graft. We also present a comprehensive review of literature on surgical management of ACD of the femoral artery.
Published: 2022
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3. Mengel, K. and Kirkby, E. A. Principles of plant nutrition

Author: D. W. Lawlor
Subjects: Plant growth, Book Reviews, media_common.quotation_subject, Pity, Plant Science, English language, Biology, Potential Subject, language.human_language, Audience measurement, German, Important research, language, Social science, Suspect, media_common
Abstract: That this text book is now in its fifth edition clearly shows the strength of its content and presentation, and its relevance to the scientific community, which should include all those interested in plants and their growth. There are 20 chapters. The first is an overview of definitions and processes which are considered in much greater depth later. Then follow substantial chapters on ‘The Soil as a Plant Nutrient Medium’, ‘Nutrient Uptake and Assimilation’, ‘Plant Water Relationships’ and ‘Plant Growth’ and ‘Crop Production’. These are the basic stuff of any such text and a number of books orientated to soil and plant processes cover them. They are well presented, clear and in considerable detail. The sixth chapter deals with fertilizer application and so is more practical, but very much based on the scientific concepts developed earlier. The effects of fertilizer use on the environment are also considered. This text provides, in the widest terms, a clearly developed, objective and balanced assessment of the current views in the subject of plant nutrition, which one might say is now in its mature phase. Twelve major plant nutrients are considered separately in sections of different length: nitrogen (34 pages), sulfur (15), phosphorus (24), etc, and there is discussion of elements which are of less importance and those with toxic effects in two further parts. So coverage of the potential subject matter is excellent. There is a good index, and extensive coverage of the literature (130 pages, perhaps 2400 citations), grouped into ‘General Reading’, related clearly to each chapter, and then ‘References’. One aspect of the book which I particularly like is that the literature covers a considerable period, as might be expected of its long history (constant regeneration), allowing the development of the subject to be appreciated. However, it may be too much to expect many to have the time to read and follow such detail. Mainly English language literature is cited, with some in German and French (with titles translated into English). Perhaps more recent literature is somewhat neglected: presumably the literature was finished in about 2000. However, this is not crucial as the book takes a more long‐term view of the topic as required, I suspect, by most of the potential readership (some undergraduates on advanced courses; researchers and professionals in many areas) who need to understand the interactions between plants, environment and nutrients. From the point of view of readers, and particularly students, the emphasis on integration of physico‐chemical and plant physiological principles and processes is well achieved and an important feature. The approach is largely descriptive, based on many examples from the literature, which are well discussed with good illustrations, tables of data and equations. Sufficient quantitative analysis is included so that most readers will be able to see the point but not be put off. Those requiring more exact analysis are directed to the literature. SI units are used throughout (so no ppm—thank goodness) but it is a pity that the explanation (page 10) using ‘130 parts of Mn (weight) per 1,100,000 parts (weight) dry matter’ was not correct. Biochemical mechanisms are nicely presented and clarify why nutrients are required. In the case of N, the link with synthesis of proteins, etc., is made, of course, but there was opportunity to make more of it in discussing the efficiency with which N is used by plants and particularly by crops. Here the modelling aspects could have been usefully expanded. Another currently very important research area that is largely not considered is molecular genetics and plant adaptation to nutrition. Given the current emphasis on this in research and teaching (and the tendency in some circles to reject work which does not include it), there is a danger that this book will not reach the audience that would benefit. However, the book provides a rich feast so readers should be well satisfied by the menu, and demanding additional dishes may be greedy. Unfortunately it is an expensive meal for individuals to purchase, and it may then compete with other similar texts on the topic. On scientific grounds and its information content, I recommend this well‐tested and substantial text to the potential readership; it should be available in all central libraries.
Published: 2004

4. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

Author: S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. Nguyen, J Farmer, M H Tan, Kwon H-S., J Yang, L Sandvik, Franco Folli, A K Jenum, M Nguyen, W Pratipanawatr, A L Frederiksen, Rebecca Smith, Lee H-J., A Schäfer, C Manuelli, G S Denver, T Vukovich, B Maceira, K Matsumoto, K. Chokkalingam, Nurcan Üçeyler, P Modi, Timothy M. Morgan, S Mertens, B M Singh, Michaela Riedl, K Iso, C Cucurullo, G. F. Bottazzo, M Calvani, K Hur, J Wetzels, Kazuhiro Takahashi, Y Aso, H Stammer, M G Masding, Fitsum Guebre-Egziabher, J L González-Sánchez, L Armstrong, Alberto Maran, Peter G.F. Swift, S S Popovic, J Starczynski, E Vitacolonna, Luigi Laviola, R W Gelling, Marina Cardellini, D Barilla, Rosa de Diego Martínez, W H Landschulz, Anne Mette Rosenfalck, R K Wong, Kevin E. Schneider, K Peros, Giuseppe Nanni, F Zhang, I Rákóczi, T Iburi, M Nakhjavani, X Q Zhang, S Tournis, Per Lav Madsen, Graham A. Hitman, A. Tura, K Laubner, N D Kostic, Lawrence M. Dolan, R. Sinha Roy, J A Wagner, J. Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. Parkinson, Claudia Sommer, C Park, F E Griffiths, M L Martí, R Demirtunc, S Taniguchi, J Lundkvist, T Siegmund, Juan Sztajzel, C Dienesch, F Baumgartner, L Scalone, T M Mckolanis, K Otake, Ullrik Pedersen-Bjergaard, T M Vriesendorp, Michael B. Wheeler, Henry Schmitt, Peter Hovind, S Lange, Stephane Roze, L. Van Gaal, B Klaproth, Anthony E. Civitarese, D Eckland, A Dagar, D F Hopkins, Kari Stefansson, C Gonzalez-Yanes, B Meyboom-de Jong, D. J. Betteridge, K Buhling, M Crepaldi, Ana M. Wägner, L Renna, L Volpe, R McBride, V Corbo, E O Brennesvik, R P Hayes, R Abdollahnia, G Viviani, C F Liew, Francisco Pérez-Bravo, Jeffrey Baron, Brian M. Frier, H H Samira, D Szentendrei, K. J. Schjoedt, W K Waldhäusl, D Gniuli, D Zou, G Tschank, V Urbančič, A L Nolan, Albertini J-P., J Malcomson, M Larbig, C Cheyssac, K Aurich, C M Kesson, S Heller, Maija E. Miettinen, R F Luco, Adrian J. Cameron, Luigi Mattiello, Z. Metelko, X E Zhang, M Parramón, I. G. Obrosova, J Fruchart, M Ilic, Björn Eliasson, Gilles Chatellier, M A Martín, D M Kendall, Holger Luthman, V F Varillas, D Maccubbin, Jang S-A., Amalia Gastaldelli, E Salzsieder, P. de Mol, A Yoshida, H D Lindner, D Gostiljac, M Just, Pan C-Y., J M Fujitaki, G Eiermann, K Bergenheim, A D Frick, A Agacdiken, K Varytimiadis, K Cseh, D A Jackson, S Calderari, Dena G. Hernandez, H M Liebich, K Min, F. de Zegher, Bernd Kulzer, K Han, Ulrich A. Müller, D Marrero, H Hatakeyama, René Koopman, Doo H-K., Petr Wohl, P. Sharp, P Forder, Thor Aspelund, N Meneveau, R M Schmülling, R Aubert, Thom Sam., H Youshikawa, M Ankelo, D Bowden, I Kelly, Frédéric Fumeron, M Sartini, Robert S. Sherwin, L Varadhan, A Criscimanna, John Betteridge, V Jelic, M Bartnik, N Lemke, B Ursø, A Bertoldo, A M Owona, H Okochi, L Pérez-Tamajó, S L Monfre, Daniel Brandhorst, K T Legg, Andries J. Smit, Veronica Sancho, Masashi Hirai, C Klein, Paul J. Thornalley, A Chaidaroglou, K Miura, B Zinman, O M Dvoynishnikova, J Plank, Jan Bolinder, C Lush, B Rubi, R Pozzilli, M Bashir, S A Shtandel, F Mosca, A Naskalska, Josef Vcelak, U Sausbier, P Cavaiani, T U Baehring, Michele Solimena, P Formisano, M Rastaldi, Bernard Thorens, J Ruzzin, E Arbit, M. Hori, Torkel B. Brismar, E Soltes Rak, A Filo, P Heinke, Matthew P. Coghlan, M Masotti, I Perevozskaya, K Ahn, I Moules, K Van Dyck, I Goldstein, Z Mathe, G Z Zhao, S Fajardo, J Taylor, S Chrul, J C Pareja, D Hadjidakis, A J Scheen, N Siddiqua, D C Cavan, R Grella, Krabbe S, H J Rochlitz, A E Hinkkanen, W Wilpshaar, Richard Stevens, M Dreyer, S Hara, X Wang, Melania Manco, D Gillen, Magalie A. Ravier, Olli Simell, John C. Lawrence, Kohnert K-D., Agardh C-D., A Berghold, L Kristensen, Grant Sfa., N Gursoy, Leif Groop, N Freemantle, Anja Schweizer, L Pala, Legros J-J., C. Di Pietro, N. Yamamoto, J Magyar, B Nikolovski, H Ikeda, D Lee, Bruce A. Buckingham, A O Wollitzer, I Kennedy, C Ernest, Neville H. McClenaghan, S Tanaka, Asimina Mitrakou, T Heinze, W Kerner, Moeenaldeen Al-Sayed, Charles Thivolet, L Klaff, A Miconi, Cristina Valeri, J. O. Christensen, K. Ekberg, A Jardine, T Endo, X Zhang, D F Child, A Kienitz, D K Seidel, H. Tada, Sylvie Abouna, Cyrus Cooper, Catherine R Chittleborough, Roberta Assaloni, S Corbi, A K Bose, K Ozawa, C Ahn, K A Deans, G Jackowski, Martin Gibson, Patrick McElduff, O A Mojiminiyi, Manuel Serrano-Ríos, O Dupuy, A L Davydov, Iwar Klimes, Sten-Anders Ivarsson, N Ichino, R Matsutomo, E R Smith, A Stefanovska, B Dehmel, K Koniavitou, E Agascioglu, M Hatazaki, J. M. Gibson, T Yada, P Ribaux, M Rupnik, K Fridell, G Scutaru, L Chugunova, Henrietta Mulnier, A Kendereski, H Lehnert, C Billi, M Sobczak, Francisco M-Mj., L K Archibald, S Sukumvanich, David B. Dunger, I. Benke, G Yillar, N Stingemore, J. M. Boavida, Y Shi, Jimmy D. Bell, L Bozzetto, Andrew J. Ahmann, E Jebens, J Keiding, Elena Henkel, Mark Fineman, J F McRae, Carol Forsblom, S Martemucci, Lourdes Ibáñez, P G Prieto, L Ringholm Nielsen, S Pratas, B von Stritzky, Julio Rosenstock, Lee K-W., J Stocks, L J Strow, I Samarguliani, L Wennekes, R Cheung, Abhishek Nag, Roberto Gambino, Y Suleymanoglu, E Murphy, T T Durck, M F Peyrot, Y Unno, Alexander Mayorov, Eleuterio Ferrannini, D. C. Rao, D Neely, H Karunajeewa, J Palmisano, Julia B. Lewis, M Ravid, G Pons, E Junca, P Vexiau, S Sailesh, D K Miloslavskiy, O N Bondarenko, U Smith, S Torri, Constantine Tsigos, Cesario Bianchi, Mattia Locatelli, D Jaquet, Virpi Lindi, M Moroi, M E Tushuizen, P Pelicci, R Scognamiglio, Pal Pacher, S M Thyssen, A Péterfalvi, Y Ho, S Guntram, L Romics, T Nakagami, Clive S. Cockram, Irina Kowalska, K Brodbeck, Gojka Roglic, J. Dörig, Lise Tarnow, Therese Tillin, A López-Alba, Martin Krššák, Moses Elisaf, S Hata, D P Snoeck, D Schmoll, O V Udovichenko, A Scaramuzza, J Paul, John H. 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Lyu, G Rizzo, V V Bogomolov, N Krasova, G M McGuire, Tina Parkner, A Timi, Johann Bauersachs, S Foussas, S A Schreiber, T Monauni, Schwarz Peh., Allenberg, J D Lee, S Dewan, Y G Zheng, D Carroll, E Sarti, C Wollheim, Anna Kaminski, C Menneila, P Bucher, Xu Jyu., Vincent Rigalleau, A Schöpfer, Hans Jörnvall, A Ben Drief, X Jeunemaitre, E Schuster, Chan Slf., S Bilgic, J Coverly, K Szafraniec, Stalenhoef Afh., H Bergert, David I. W. Phillips, J Maksimovic Pavlovic, Sergio E. Starkstein, E Chaim, T Lehmann-Lintz, P Salacone, Tim Armstrong, Ingrid Klöting, C M Frampton, Franco Cavalot, A.K.Azad Khan, H Rose, Marta Letizia Hribal, Jette Kolding Kristensen, H Gröbe, M Nishi, A Vanderplas, Howlett Hsc., L E Bowen, R Malik, A Wu, Charles C. Richardson, Y Li, P G McNally, Yoon K-H., A Baleydier, M J Murphy, P. M. Nilsson, U Lindblad, Sten Madsbad, T Bíró, Riitta Veijola, Charlotte Glümer, Assunta Pandolfi, Lydia Aguilar-Bryan, M Namba, C Franzen, S Lopatriello, David Russel Jones, S. 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Jeffcoate, J Pariès, K Huoponen, Anne Jörns, G Shanmugam, A Tsiavou, S Yoshida, Kim M-J., Annapaula Giulietti, S Paillasson, K Tsuchiya, Divyen K Shah, P Saar, S S Juarez, Stefanie Maxion-Bergemann, J Briody, V Schmitz, C M Pena, J Fernádez-Real, S Naruse, M Kalis, A P Klimenko, X H Chen, H.H. Lervang, G Bock, Mirja Tiikkainen, J Potockova, N Pekcanli, George Dragicevic, Timothy M. Rose, David C. Goff, H Komori, V Vasseur-Delannoy, S Hanley, P Hajos, C W Ahn, Matsuoka T-A., J Burns, Petar M. Seferovic, Yuki Kita, K Lyons, K Kohri, Eleftheria Zeggini, Y Ding, G Belcher, Steven V. Edelman, N Dinççaǧ, Christopher J. Rhodes, Manders Rjf., S Giveon, Dario Iafusco, L Li, M C Ribaudo, Kang S-K., Laurie J. Goodyear, L Martinez, C Vermigli, H Dabire, R Raymond, J de Haan, Christopher J. Groves, Å Norberg, H Jahr, M Gloster, Christopher D. 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Leon, Alberti Gkm., A Opel, S Kokkoris, S B Hong, Philippe Courtois, L Haque, Maria Sörhede Winzell, M C Beauvois, A Szypowska, D Yu, M Gutniak, D Petzinna, B Isomaa, K S Prickett, Maria Felice Brizzi, Pavel Hamet, P J Hammond, K. F. Michelmore, Yumie Takeshita, N Hariharan, Corrado M. Cilio, G Pogatsa, W G Jerome, E Bartley, K Schlembacher, G Blohmó, Guy A. Rutter, Kyung Mook Choi, S. C Tamer, Felix K. Assah, K A Jandeleit-Dahm, M Chan, H Darius, Jørgen F. P. Wojtaszewski, A Papazisi, M Amaya, A Knopff, M Tadayyon, I J Kim, W Russ, T Myrnäs, M. Tryon, S Poonsatha, Noel Cameron, Kim M-H., Alejandra Tomas, F Homo-Dekarche, G. Di Cianni, M Stotzka, C Solimine, Mikhail Borisovich Antsiferov, H Naserke, M Bianchi-Biscay, J I Lara, Moon C-K., Alain Ktorza, Alison N. Jeffery, V Lilla, Eun Seok Kang, Hanley Ajg., J Widder, R Ratner, C Goretti, P J Weston, J Perkins, V Rasmussen, M Evans, T M Gibson, A Jaffe, S I Chisalita, C Owman, L Hiltunen, E Kakishita, C M Mack, H C Potter, M Femerling, M Desai, M Soinio, K Yang, Patricia L. Brubaker, M Meyer, V Dy, J Berden, R Komers, Milos Adamec, R Petzoldt, Alan G. Robinson, R Stevens, A Doi, A Leunda, Eduard Montanya, Alessandra K Cardozo, N Kraenkel, Claudio Cobelli, U A Mueller, S Yamashiro, B R Gedulin, G Francisco, J Dennenmoser, Lesch K-P., Martin G. Bischof, M Ichita, C Fernandes, Jochen Hampe, S Kern, D Kelly, E Zeender, P Perna, J D Best, A C Calkin, Vivian Fonseca, J Prestle, D G Parkes, Satish K. Garg, T Burrell, B M Fischer, D Kruger, J S Skinner, Lin T-M., Jozef Ukropec, Maria Jeziorska, K Arii, David D. D’Alessio, M B Gomes, L Quandt, I Fragaki, M C Brindisi, A Gladkih, E Kitsou, S Di Cola, T Iwasaki, Peter Diem, T Lakka, V V Popova, G Lee, Hannah J. 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Cavanagh, Allen Taylor, M Balabolkin, G Schreier, E Stern, J Lips, V Serban, G Sparacino, Roser Casamitjana, Aine McKillop, I Groza, E Bernal, Kathleen M Gillespie, T Ledet, A Garzaniti, F Hawkins, K M Tushaus, C Renaudin, Christina Maier, A Dormi, A Ubertalli, Inge Tetens, M Ostojic, E Pierre-Justin, A Bhushan, E Ur, L I Jeltova, Tilo Moede, E Tibiriça, Zoran Gucev, Knoch K-P., G Pizzolanti, A M Şengül, T P Degenhardt, Cristina Lencioni, M Fitchet, E Santini, E Devangelio, C Panaite, Y I Karachentsev, S B Solerte, Christos Manes, M Lipka, C H Teng, P Mrak, G Fegan, R C Milton, M Negrean, Astrid Plamboeck, L Patti, M Houk, Ritva Kauppinen-Mäkelin, Christoph F Ebenbichler, O Sysoyeva, Frantisek Saudek, H Wysocki, Robert A. Rizza, J Altirriba, Bjørn Richelsen, L. Lam, Rémy Burcelin, A Antsaklis, G Galimberti, R. de Vries, A Lewin, Marcia A. 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Vingrys, S Habu, Mariella Trovati, H Sobajima, Pierre Lecomte, Kim T-H., D Virsaladze, M Oprean, F Pullen, A Rußmann, G J Bruining, Martina Düfer, Wen Xu, Min Y-K., Norman E Cameron, Gianfranco Pagano, K Harley, M Su, J P Le Berre, Sian Ellard, S Howard, D Russell-Jones, Z Li, S Carpenter, E L Thomas, W Tang, Lee M-S., N Ubrich, M. M. McMahon, G Vassilikos, N Brossa, M S Joergensen, S Smith, A Vania, Y Laurent, S Basir, A Freudenthaler, Sally M. Marshall, D Niedermayer, V I Pankiv, J Mentel, S Pruna, J M Pou Torelló, Y Ito, G Chrysos, Werner Kramer, Hironori Yamasaki, L Bowman, F Palumbo, P Ruth, G Lankas, Z H Liao, D Park, W Otter, C Montrone, Sevasti Zervou, Jennifer L. Wilkinson-Berka, Bo Feldt-Rasmussen, I Banu, Paolo Sbraccia, Bani Mukhopadhyay, Mark E. Cooper, M Kidron, Pål R. Njølstad, A M Jonsdottir, M R Burge, G Valpiani, Yutaka Oiso, David J. 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Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
Subjects: 0303 health sciences, medicine.medical_specialty, business.industry, EASD, Endocrinology, Diabetes and Metabolism, Human physiology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Family medicine, Internal Medicine, Medicine, business, 030217 neurology & neurosurgery, 030304 developmental biology
Published: 2004

5. Society for Social Medicine and the International Epidemiological Association European Group. Abstracts of oral presentations

Author: S. L. Thomas, J. A. G. Whitworth., J. Brazier, N. T. Fear, A. McLeod, J. Rosenbauer, L. Lennon, J. M. M. Evans, P. N. Appleby, S. Cliffe, B. Tobiasz-Adamczyk, J. A. Gilg, K. Macintyre, A. Morgan, U. Nath, A. Brennan, D. Bhakta, P. M. Sturdy, P. Silcocks, C. R. West, J. Rankin, S. Adamek, M. Cahill, A. Leiva, G. Surman, A. J. Boyd, J. L. Townsend, D. Linos, C. G. Owen, M. Campbell, R. Lall, A. Memon, H. Twomey, W. C. S. Smith, I. D. S. Silva, K. M. Laurence, D. J. Burn, M Clarke, K. G. M. M Alberti, S. Y. Ho, M. McKee, M. Brett, R. Pill, F.C. Lampe, A. Whelan, J. L. Donovan, C. Gillis, R. Clarke, S. Moebus, P. Tynelius, C. Macleod, R. Knibb, J. Saunders, I.J. Perry, L. Watson, I. Pell, H. R. Anderson, S.E. Humphries, D. Fouskakis, M. Kulig, A. S. Poobalan, S. Pattenden, C. Donovan, P. Bundred, T. Fahey, Redpath, R. Small, C. Ronsmans, L. J. Vatten, H. Graham, D. Marks, Y. B. Shlomo, E. McIntosh, N. Winer, M. Cork, G. Costa, P. Herzig, Z. J. Brzezinski, A. Suokas, F. Dobbie, D. A. Cromwell, E. Banks, D. Fone, D. G. Cook, A. Barton, A. McCulloch, L. Li, A. Ludbrook, K. T. Khaw, M. Cosson, A. Ego, S.-L. Hove, D. Davies, J. Munro, S. E. Bromley, E. Lyamuya, J-M Robine, D. Stanistreet, C. Borrell, T. J . Key, D. E. Neal, K. Rees, M. Abdelnoor, M. Goldacre, J. Seckl, M. Langer, P. H. Whincup, M. May, S. Morton, J. E. J. Gallacher, J. Gilg, J. Donovan, G. Giani, M. Reilly, E. Brunner, M. Rahu, C. Belfield, J. Mazur, J. Harding, R. J. Lancashire, D. Florin, D. Dedman, M. Cardano, A. Doring, T. J. Peters, D. Canoy, E. Sherratt, P. Moffatt, W. Anderson, F. Birrell, A. Finlayson, N. J. Spencer, N. Lehmann, M. S. Gilthorpe, G. T. Jones, C. Pope, T. Schofield, H. Hemingway, G. J. Macfarlane, A. Linos, R. Campbell, G. D. Angelini, P. Rose, B. Armstrong, I. Matthews, R.W. Morris, J. Mackay, M. J. Campbell, M. Mugford, F. Sampson, S. Welch, T. Spadea, F. Legoueff, R. Gupta, J. Sundquist, R. R. Jeffrey, Z. H. Krukowksi, R. D. T. Farmer, J. Dowie, L. Cook, E. Falaschetti, J. Gallacher, A. Coulter, D. Braunholtz, R. Smith, A. J. Hall, A. Papadopoulos, C. L. Hart, L. Thorpe, K. Kivela, J. White, J. A. Rottingen, D. Shickle, C. R. Victor, H. Winter, L. Maina, H. Rawson, M. O'Reilly, D. R. Altmann, P. Martikainen, B. K. Butland, M. Osler, A. O'Cathain, N. R. Poulter, G. Macfarlane, H. Kitundu, E. Johnstone, S. V. Glinianaia, C. B. J. Woodman, S. Brown, V. Ajdacic-Gross, A. Bailey, K Porter, K. L. Woods, N. Calvert, H. Brown, N. Kr. Rasmussen, L. Jones, R. Araya, P. Patel, R. Walton, N. Maconochie, J. Acuna, D. Mant, N. E. Allen, M. F. Peeters, A. Silman, M. Cartman, S. Goodacre, T. Tuominen, J.I. Elstad, M. Guillemin, D. Subtil, D. Creagh, P. Smith, E. Watson, N. Lester, G. S. Tell, S. Wild, D. A. Griffiths, P. Yudkin, M. Kumari, N. Moss, A. D. Morris, M. Gissler, M. Gronbak, C. Read, I. M. Harvey, M. C. Watson, M. Khlat, S. Darby, A. J. McMichael, F. Dunstan, G. Higgs, P. Armaroli, C. M. Wright, J. Grimshaw, V. Bhavnani, S. J. Armstrong, R. Andrew, H. Smith, N. Middleton, D. A. Leon, K. H. Mak, D. Bick, J. E. Mueller, H. Straatman, T. Key, H. Lowel, D. Yeates, J. I. Hawker, W. A. Markham, R. Hooper, H. Hutchings, D. Morrison, R. F. Harvey, P. Mangtani, P. Hawe, T. H. Lam, K. Szafraniec, C. Wilman, C. M. Wong, J. Biddulph, S. Binting, D. Cook, E. Roman, D. Forman, J. Rahi, M. Rimpela, L. J. Murray, R. Tuimala, K. Nanchahal, V. Seagroatt, J. G. Wheeler, G. P. Garnett, J. Bruce, K. Paine, A. Johansen, A. G. Thomson, G. Harrison, M. Quigley, J. Gunn, J. Thoburn, L. Sharp, J. Nagano, N. E. Haites, M. Crilly, J. Hallqvist, P. Tookey, A. Nieto, Z. A. K Walker, G. Erikssen, R. Ascione, A. Jahn, J. J. V. McMurray, A. Clements, C Jagger, M. M. Rovers, J. F. P. Schellekens, Z. Hurst, J. M. Borras, A. Fuller, D. Pope, M. Somerville, P. Mowinckel, A. Daly, J. Mindell, H. Newdick, H. C. Boshuizen, A. Crampin, P. Fryers, N. Noah, D. Ogilvie, E. Breeze, J. Bell, L. S. Young, A. Suresh, L. Oakley, J. Erikssen, G. Wannamethee, H. Neil, A. J. Lees, E. Riza, F. Hamers, S. Marshall, J. Hughes, H. Macpherson, J. Robinson, C. Foy, E. Dolan, A. Levcovich, I. Barnes, C. McGrother, S. E. Johansson, K. Thomas, P. Veerus, J. P. Pell, A. Clarke, R. Suckling, H. Tunstall-Pedoe, F. Rasmussen, R. G. Thomson, A. J. Hedley, M. L. Burr, M. Roman, S. Karvonen, J. W. Den Boer, D. A. Lawlor, J. McCarthy, V. Beral, G. K. Davey, M. Quinn, R. C. Wilson, D. Lamont, J. Little, E. Dahl, P. Yudkkin, M. A. Yngwe, T. Q. Thach, H. Pikhart, D. Batty, O. Razum, P. M. Ueland, H. Kuper, W. A. Chambers, N. Norris, S.E. Oliver, S. N. Willich, R. Lilford, R. A. Odegard, A. Schiaffino, A. Fletcher, M. Joffe, N. W. Wood, R. Davies, G. A. Zielhuis, D. Chase, D. Eich, S. Taylor, S. Mayor, T. M. Kauppinen, J. Muller-Nordhorn, P. Elwood, M. C. Gulliford, F. Diderichsen, C. Macarthur, S.N.I. Loningsigh, B. Nikiforov, J. Williams, C. Whyman, M. Egger, K. AL-Saleh, M. Ely, S. A. Stansfeld, M. Senior, R. R. West, N. C. Nevin, A. Macfarlane, S. E. Neppelenbroek, K. Odoki, R. F. A. Logan, P. Chau, C. Scherf, T. Brammah, M. Ruiz, O. Basso, H. Gee, A. Kamali, G. Liratsopulos, D Gunnell, M. A. E. C.-V. Spaendonck, R. Haward, G. T. H. Ellison, J. G. Evans, G. Reeves, P. Belderson, A. Dennehy, A. H. Leyland, B. Alden, R. A. Lyons, S. Nielson, G. Williams, P. Richmond, O. Rahkonen, H. Refsum, I. Markaki, J. Watkins, D. Leon, R. Travis, D. Wonderling, H. R. Morris, S. Griffiths, B. P. Dineen, T. Walley, R. Rose, D. Querleu, O. Manor, G. J. Johnson, D. Wood, S. Prior, P. Pharoah, E. M. I. Williams, G. Steiner, J. W. G. Yarnell, M. C. Thomas, V. McCormack, F. C. Taylor, M. Urwin, A. McDonagh, A. Nicoll, J. P. Connaghan, M. Garcia, P. Ansell, J. Olsen, R. R. Bourne, J. Emberson, J. A. Lane, M. E. Black, M. Hakama, I. Blair, D. W. Cramer, B. Jefferis, I. Bowns, J. M. Bland, F. C. Hamdy, E. Prescott, S. Frankel, P. M. King, S. Stansfeld, L. Sandvik, C. Wright, P. Redgrave, N. Drury, K. Wishart, H. Daniels, E. A. Spencer, R. Sainsbury, R. Reading, N. J. D. Nagelkerke, K. Abrams, S. Roberts, J. M. Grimshaw, A. McCarthy, W. Y. Cheung, G. Feder, S. T. Nilsen, E. Salto, M. McCarthy, P. Zagozdzon, C. Salmond, G. Rojas, T. Allison, G. Engholm, H. Lambert, G. D. Smith, Matthews, J. Carlisle, R. Turner, R. Boaden, J. Yarnell, A. Chapple, L. Kurina, C. E. D. Chilvers, F. Rasul, L. Sevak, N. J. Wareham, N. Spencer, I. Shoham-Vardi, D. Beyleveld, L. Brindle, P. Bhandari, C. I. F. Rooney, A. Love, R. White, H. L. Bradlow, D. Biggerstaff, R. Gnavi, S. Jackson, A. A. Montgomery, G. Walraven, M. Rush, L. Titus-Ernstoff, A. Maddocks, J. W. T. Chalmers, D. Crabbe, S. Shepperd, J. Stefoski-Mikeljevic, B. D. E. Stavola, M. Petticrew, L. Moore, P. J. Babb, V. Houfflin-Debarge, T. Valkonen, M. Walker, K. Ntalles, R. Lancashire, G. J. Miller, M. Tobias, H. Dallosso, J. A. C. Sterne, P. Kintu, J. I. Mann, M. Morgan, V. Shkolnikov, O. C. Ukoumunne, M. Lundberg, T. Chandola, J. Lumley, A. E. Raffle, H. Thomson, P. Doyle, S. Ebrahim, G. Green, E. Nurk, K. Hey, E. Roos, M. Fitter, A. Shiell, P. Aveyard, J. Birks, A. Kudzala, M. Darif, E. Mierzejewska, S. M. Ali, M. Page, S. Ziebland, A. McPherson, R. Thomas, M. Tiefenthaler, L. Carpenter, H. Deo, O. Nygard, J. Stieber, D. P. M. Symmons, C. Power, P. Sherliker, E. Whitley, M. Collins, D. J. O'Halloran, Z. Uren, C. Jenkinson, A. W. Craft, J. Kengeya-Kayondo, C. Henderson, F. Vannoni, W. Brown, P. Pound, O. Lundberg, S. Checkley, W. Rossler, A. H. Harding, S. Gillam, J. Raftery, U. B. Fallon, G. Schofield, H. Prosser, D. Stockton, L. Shepstone, M. Demaria, D. Symmons, L. Parker, I. Harvey, M. Juneja, W. L. Wrieden, J. Austoker, N. Brockton, M. Pakkanen, A. B. Gilmore, B. Thorand, D. Weitzman, A. Thomson, S. Gallivan, L. Wright, M. Bobak, B. Purcell, G. M. Leung, P. Due, M. Grimsley, P. O. Olausson, K. K Cheng, S. Quine, A. Redpath, W. Ahrens, T. J. Williams, H. M. Fielder, V. S. Raleigh, P. O. D. Pharoah, J. A. Van Vliet, R. Chen, S. Neilson, J. Mollison, R. Pearce, S. Wallace, I. Hunt, J. Logie, B. Walker, A. R. Ness, O. Papacosta, J. Pickering, S. Bewley, M. Phillips, G. Lewis, K. Bromen, C. Sauvaget, R Hinchion, B L De Stavola, M. Upton, A. Lucassen, M. J. Goldacre, R. Austgulen, K. Marinko, N. Richards, C. Wolfe, A.G. Shaper, P. C. Elwood, R. E Fritsch, B. Olowokure, S. Bruster, A. C. Papageorgiou, M. Malmstrom, M. Murphy, S. Murphy, M. Ramsay, C. S. de Vries, A. Majeed, E. Morris, M. Brandon, P. Corcoran, A. Johnson, T. I. L. Nilsen, D. W. Sepkovic, A. J. Silman, M. O'Brien, K. H. Jockel, S. Collins, R. J. Lilford, P. Crampton, M. Bopp, D. Dorling, L. Zaborski, B. L. Harlow, A. Berrington, C. Johnston, L. Morison, S. R. Palmer, P. Primatesta, A. Vikat, K. Cooper, E. Lahelma, H. Pohlabeln, M. Marmot, A. Bullock, M. Shipley, E. Hemminki, K. Christensen, E. Nolte, H. Voller, S. Kinra, S. Mazloomzadeh, E. McNeilly, J. E. C. Sedgwick, M. Basham, P. McCarron, J. Cassidy, R. Miller, K. Macrae, E. Fernandez, S. J. Walter, J. Nicholl, R. Scholz, P. Whincup, J. Kinsman, S. Stewart, S. E. Vollset, K-H. Jockel, M. Roxby, J. Sheehan, S. Jones, K. D. Watson, A. N. Andersen, A. Herxheimer, J. Critchley, D. Bull, H. Knowles, R. Warren, D. R. Boniface, L. T. Lennon, I. Shemilt, A. Kennedy, I. Jahn, R. Villegas, A. Stang, D. M. N. Huq, P. Roderick, C. Bukach, S. C. Cotton, R. Lawrenson, M. Thorogood, F. Faggiano, N. Britten, S. Capewell, I. Lissau, M. Donaldson, C. M. Bond, Y. Ben-Shlomo, M. Barter, M. Moher, M. Waterstone, R. Doll, A. J. Pearce, M. Utley, and F. Gutzwiller
Subjects: medicine.medical_specialty, Abstracts, Epidemiology, Social medicine, business.industry, Family medicine, Public Health, Environmental and Occupational Health, medicine, Alternative medicine, Association (psychology), business
Published: 2001

6. Apoptosis and Accidental Cell Death in Cultured Human Keratinocytes after Thermal Injury

Author: Jennifer R. Mata, D F Lawlor, Natalia P. Matylevitch, Steven T. Schuschereba, Phillip D. Bowman, Cleon W. Goodwin, and George R. Gilligan
Subjects: Keratinocytes, Pathology, medicine.medical_specialty, Programmed cell death, Hot Temperature, Time Factors, Cell Survival, Blotting, Western, Apoptosis, Biology, Pathology and Forensic Medicine, medicine, Humans, HSP70 Heat-Shock Proteins, Viability assay, Fragmentation (cell biology), Cells, Cultured, TUNEL assay, Cell Death, Molecular biology, Staining, Mitochondria, Microscopy, Electron, medicine.anatomical_structure, Cell culture, Tumor Suppressor Protein p53, Keratinocyte, Regular Articles
Abstract: The respective roles of apoptosis and accidental cell death after thermal injury were evaluated in normal human epidermal keratinocytes. By coupling the LIVE/DEAD fluorescence viability assay with the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) method and ultrastructural morphology, these two processes could be distinguished. Cells were grown on glass coverslips with a microgrid pattern so that the results of several staining procedures performed sequentially could be visualized in the same cells after heating at temperatures of up to 72 degrees C for 1 second. After exposure to temperatures of 58 to 59 degrees C, cells died predominantly by apoptosis; viable cells became TUNEL positive, indicating degradation of DNA. After exposure to temperatures of 60 to 66 degrees C, both TUNEL-positive viable cells and TUNEL-positive nonviable cells were observed, indicating that apoptosis and accidental cell death were occurring simultaneously. Cells died almost immediately after exposure to temperatures above 72 degrees C, presumably from heat fixation. The fluorescent mitochondrial probe MitoTracker Orange indicated that cells undergoing apoptosis became TUNEL positive before loss of mitochondrial function. Nucleosomal fragmentation of DNA analyzed by enzyme-linked immunosorbent assay and gel electrophoresis occurred after exposure to temperatures of 58 to 59 degrees C. The characteristic morphological findings of cells undergoing apoptosis, by transmission electron microscopy, included cellular shrinkage, cytoplasmic budding, and relatively intact mitochondria. Depending on temperature and time of exposure, normal human epidermal keratinocytes may die by apoptosis, accidental cell death, or heat fixation.
Published: 1998

7. Obesity and use of acute hospital services in participants of the Renfrew/Paisley study.

Author: C. L. Hart, D. J. Hole, D. A. Lawlor, and G. Davey Smith
Subjects: OBESITY, OVERWEIGHT persons, BODY weight, HOSPITAL utilization, HOSPITAL admission & discharge
Abstract: Background Because overweight and obesity are associated with comorbidities, increasing levels of overweight and obesity may impact on hospital use.Methods Body mass index (BMI) in middle age was related to acute hospital use in 7036 men and 8327 women from the Renfrew/Paisley prospective cohort study in Scotland. Participants in this general population study were examined between 1972 and 1976 when aged 45–64 years. Acute hospital admissions and bed days per 1000 person-years were calculated by the World Health Organization BMI categories in the follow-up period to 31 March 2004.Results Underweight and normal weight men had lower-than-expected admission rates, and overweight and obese men had higher-than-expected admission rates. Obese men had higher-than-expected bed day rates. For women, there was a U-shaped relationship with admission rate, with normal weight women having the lowest admission rate and underweight and obese women having similar high rates. Underweight and obese women had higher-than-expected bed day rates.Conclusions Participants who were obese in midlife had more-than-expected acute hospital admissions and in particular more bed days. With levels of obesity increasing since this study was started in the 1970s, if these patterns persist, there may be increasing demand on health service resources. [ABSTRACT FROM AUTHOR]
Published: 2007
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8. Aortic dilatation after endovascular repair of blunt traumatic thoracic aortic injuries

Author: D. Kirk Lawlor, Thomas L. Forbes, Jeremy R. Harris, and Guy DeRose
Subjects: Adult, medicine.medical_specialty, Time Factors, Thoracic Injuries, Computed tomography, Aorta, Thoracic, Wounds, Nonpenetrating, Aortography, Blood Vessel Prosthesis Implantation, Young Adult, Blunt, medicine.artery, Medicine, Thoracic aorta, Humans, Aged, Aortic dilatation, Aged, 80 and over, Ontario, Aorta, medicine.diagnostic_test, Aortic Aneurysm, Thoracic, business.industry, Mean age, Middle Aged, Confidence interval, Surgery, Treatment Outcome, Left subclavian artery, Radiology, business, Cardiology and Cardiovascular Medicine, Tomography, X-Ray Computed, Dilatation, Pathologic
Abstract: Objective Endovascular repair of blunt traumatic thoracic aortic injuries (BTAI) has become routine at many trauma centers despite concerns regarding durability and aortic dilatation in these predominantly young patients. These concerns prompted this examination of thoracic aortic expansion after endovascular repair of a BTAI. Methods The immediate postoperative and most recent computed tomography (CT) scans of patients who had undergone urgent endovascular repair of a BTAI and had at least 1 year of follow-up were reviewed. Diameter measurements were made at four predetermined sites: immediately proximal to the left subclavian artery (D1), immediately distal to the left subclavian artery (D2), distal extent of the endograft (D3), and 15 mm beyond the distal end of the endograft (D4). Split screens permitted direct comparison of measurements between CTs at the corresponding levels. Results During a 6-year period (2001-2007), 21 patients (mean age, 42.9 years; range, 19-81 years) underwent endovascular repair of a BTAI, 17 with at least 1 year of follow-up (mean, 2.6 years; range, 1-5.5 years). No patients required reintervention during this period. The mean rate of dilatation for each level of the thoracic aorta in mm/year was: D1, 0.74 (95% confidence interval [CI], 0.42-1.06); D2, 0.83 (95% CI, 0.55-1.11); D3, 0.63 (95% CI, 0.37-0.89); D4, 0.47 (95% CI, 0.27-0.67). The rate of expansion of D2 differed significantly vs D4 ( P = .025). Conclusions During the first several years of follow-up, the proximal thoracic aorta dilates minimally after endovascular repair of BTAIs, with the segment just distal to the left subclavian artery expanding at a slightly greater rate. Longer-term follow-up is necessary to determine whether this expansion continues and becomes clinically significant.
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9. Comparison of renal function after endovascular aneurysm repair with different transrenally fixated endografts

Author: Kenneth A. Harris, Guy DeRose, D. Kirk Lawlor, Thomas L. Forbes, and Gregory E.J. Harding
Subjects: Male, medicine.medical_specialty, medicine.medical_treatment, Renal function, Kidney, Prosthesis Design, Endovascular aneurysm repair, Computed tomographic, Accessory renal artery, Blood Vessel Prosthesis Implantation, Aortic aneurysm, Aneurysm, medicine, Humans, Aged, Retrospective Studies, Fixation (histology), Aged, 80 and over, business.industry, Vascular disease, Suture Techniques, Angiography, Middle Aged, medicine.disease, Blood Vessel Prosthesis, Surgery, Treatment Outcome, Creatinine, Female, Radiology, business, Cardiology and Cardiovascular Medicine, Aortic Aneurysm, Abdominal, Follow-Up Studies
Abstract: Objective Transrenal fixation of abdominal aortic endografts may provide a more secure proximal attachment with few deleterious effects with respect to renal function. This study's purpose was to determine whether different metals used in two commercially available endografts (Cook Zenith and Medtronic Talent) result in different effects on renal function when placed across renal ostia. Methods A total of 140 consecutive patients, between August 2003 and April 2005, who underwent elective endovascular repair of an aortic aneurysm with a nitinol or stainless steel–based endograft with transrenal fixation were reviewed with a mean follow-up period of 5.5 months (range, 1-22 months). The main outcome variable was the percentage change in creatinine clearance (CrCl), which was determined before surgery and at the most recent follow-up. Multiple regression analysis was performed to analyze the contribution of various factors to any deterioration in renal function. Results The 140 patients were predominantly male (86%), with a mean age of 75 years (range, 56-92) and a mean aneurysm diameter of 62 mm (range, 42-110 mm). The mean intraoperative contrast use was 67 mL (range, 45-160 mL), and after surgery these patients received a mean of 3 surveillance computed tomographic scans (range, 1-7). Nineteen cases (13.6%) required deliberate accessory renal artery coverage. CrCl did not change significantly after surgery; the mean change in CrCl at the end of follow-up was a 2.5% decrease. There was no difference in the reduction in CrCl between endograft types. Only 14.3% of patients experienced a greater than 20% decrease in CrCl. Multiple regression analysis failed to show a relationship between change in renal function and age, sex, aneurysm diameter, infrarenal neck dimensions, endograft type, coverage of accessory renal arteries, intraoperative contrast volume, preoperative CrCl, and postoperative computed tomographic scans. Length of follow-up was an independent predictor ( P = .04). Conclusions Transrenal endograft fixation results in little deterioration in renal function during intermediate follow-up. The few patients who do experience a decline in renal function do so independently of any features related to the initial endovascular repair, and there is no difference in renal deterioration between endografts with nitinol and stainless steel transrenal bare metal stents.
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10. Cytokines contribute to early hepatic parenchymal injury and microvascular dysfunction after bilateral hindlimb ischemia

Author: Robert W. Brock, Kenneth A. Harris, D. Kirk Lawlor, and Richard F. Potter
Subjects: Male, Pathology, medicine.medical_specialty, Multiple Organ Failure, medicine.medical_treatment, Ischemia, Antibodies, Random Allocation, Postoperative Complications, medicine, Animals, Rats, Wistar, Coloring Agents, Cell Nucleus, Cell Death, Tumor Necrosis Factor-alpha, business.industry, Liver Diseases, Microcirculation, Organ dysfunction, Interleukin, Alanine Transaminase, medicine.disease, Hindlimb, Rats, Disease Models, Animal, Portal System, medicine.anatomical_structure, Cytokine, Liver, Reperfusion, Surgery, Tumor necrosis factor alpha, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Perfusion, Intravital microscopy, Interleukin-1, Liver Circulation, Propidium, Blood vessel
Abstract: Purpose: Hepatic dysfunction may contribute to death from multiple organ dysfunction after abdominal aortic surgery. Several factors are likely responsible, and the purpose of this study was to determine whether the cytokines tumor necrosis factor-α (TNF-α) and interleukin 1 (IL-1) are involved in initiating this remote hepatic injury. Methods: In a normotensive rat model of 4-hour bilateral hindlimb ischemia/reperfusion (I/R), we measured systemic TNF-α and IL-1 levels throughout the I/R period. Rats were randomly assigned to either the 3-hour control group, the 3-hour I/R group, or the I/R group with administration of a polyclonal antibody (PAb) to TNF-α (I/R + TNF-α PAb). Direct evidence of lethal hepatocyte injury through the labeling of nuclei by propidium iodide (per 10–1mm3) and altered microvascular perfusion were assessed by using intravital microscopy. Results: Systemic TNF-α peaked at 83.97 pg/mL (P < .05, n = 5) at 30 minutes of reperfusion and returned to baseline in 60 to 90 minutes. No significant change in systemic IL-1 was detected (P < .05, n = 4). Alanine aminotransferase increased 2.5-fold in the I/R group through 3 hours of reperfusion (P < .05, n = 4), and TNF-α PAb did not attenuate this alanine aminotransferase increase (P < .05, n = 6). Lethal hepatocyte injury increased by 8-fold in the I/R group compared with the control group (P < .05, n = 5), whereas TNF-α PAb significantly reduced this injury (P < .05, n = 4). No regional differences in injury were noted within the acinus. Total perfusion within the microvascular unit did not drop; however, significant flow heterogeneity was observed. The proportion of continuously perfused sinusoids declined in the I/R group after 3 hours of reperfusion in both periportal (62.0 ± 2.2, P < .05) and, to a lesser, although significant, degree, in the pericentral regions (73.2 ± 1.73, P < .05). Conclusion: By scavenging extracellular TNF-α with a PAb, we provide direct evidence that TNF-α contributes to, but is not solely responsible for, early remote hepatocellular injury and microvascular dysfunction. The administration of TNF-α PAb reduced lethal hepatocyte injury in both regions of the acinus and also improved perfusion in the periportal region (76.8 ± 5.41, P < .05), but not in the pericentral region. This suggests that TNF-α released during reperfusion mediates early remote hepatocellular injury and microvascular dysfunction after a remote ischemic insult. (J Vasc Surg 1999;30:533-41.)
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11. Changing epidemiology of bacterial meningitis among adults in England and Wales 1991–2002.

Author: A. B. GJINI, J. M. STUART, D. A. LAWLOR, K. A. V. CARTWRIGHT, H. CHRISTENSEN, M. RAMSAY, and R. S. HEYDERMAN
Published: 2006
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12. Metabolomics datasets in the Born in Bradford cohort.

Author: Taylor K, McBride N, J Goulding N, Burrows K, Mason D, Pembrey L, Yang T, Azad R, Wright J, and A Lawlor D
Abstract: Metabolomics is the quantification of small molecules, commonly known as metabolites. Collectively, these metabolites and their interactions within a biological system are known as the metabolome. The metabolome is a unique area of study, capturing influences from both genotype and environment. The availability of high-throughput technologies for quantifying large numbers of metabolites, as well as lipids and lipoprotein particles, has enabled detailed investigation of human metabolism in large-scale epidemiological studies. The Born in Bradford (BiB) cohort includes 12,453 women who experienced 13,776 pregnancies recruited between 2007-2011, their partners and their offspring. In this data note, we describe the metabolomic data available in BiB, profiled during pregnancy, in cord blood and during early life in the offspring. These include two platforms of metabolomic profiling: nuclear magnetic resonance and mass spectrometry. The maternal measures, taken at 26-28 weeks' gestation, can provide insight into the metabolome during pregnancy and how it relates to maternal and offspring health. The offspring cord blood measurements provide information on the fetal metabolome. These measures, alongside maternal pregnancy measures, can be used to explore how they may influence outcomes. The infant measures (taken around ages 12 and 24 months) provide a snapshot of the early life metabolome during a key phase of nutrition, environmental exposures, growth, and development. These metabolomic data can be examined alongside the BiB cohorts' extensive phenotype data from questionnaires, medical, educational and social record linkage, and other 'omics data., Competing Interests: Competing interests: DAL has received support from Medtronic LTD and Roche Diagnostics for biomarker research that is not related to work presented here. The other authors report no conflicts., (Copyright: © 2021 Taylor K et al.)
Published: 2021
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13. Ascertaining and classifying cases of congenital anomalies in the ALSPAC birth cohort.

Author: Taylor K, Thomas R, Mumme M, Golding J, Boyd A, Northstone K, Caputo M, and A Lawlor D
Abstract: Congenital anomalies (CAs) are structural or functional disorders that occur during intrauterine life. Longitudinal cohort studies provide unique opportunities to investigate potential causes and consequences of these disorders. In this data note, we describe how we identified cases of major CAs, with a specific focus on congenital heart diseases (CHDs), in the Avon Longitudinal Study of Parents and Children (ALSPAC). We demonstrate that combining multiple sources of data including data from antenatal, delivery, primary and secondary health records, and parent-reported information can improve case ascertainment. Our approach identified 590 participants with a CA according to the European Surveillance of Congenital Anomalies (EUROCAT) guidelines, 127 of whom had a CHD. We describe the methods that identified these cases and provide statistics on subtypes of anomalies. The data note contains details on the processes required for researchers to access these data., Competing Interests: Competing interests: D.A.L reports support from Roche Diagnostics and Medtronic Ltd for research unrelated to that presented here. All other authors declare no conflicts of interest., (Copyright: © 2021 Taylor K et al.)
Published: 2021
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14. Ascertaining and classifying cases of congenital anomalies in the ALSPAC birth cohort.

Author: Taylor K, Thomas R, Mumme M, Golding J, Boyd A, Northstone K, Caputo M, and A Lawlor D
Abstract: Congenital anomalies (CAs) are structural or functional disorders that occur during intrauterine life. Longitudinal cohort studies provide unique opportunities to investigate potential causes and consequences of these disorders. In this data note, we describe how we identified cases of major CAs, with a specific focus on congenital heart diseases (CHDs), in the Avon Longitudinal Study of Parents and Children (ALSPAC). We demonstrate that combining multiple sources of data including data from antenatal, delivery, primary and secondary health records, and parent-reported information can improve case ascertainment. Our approach identified 590 participants with a CA according to the Euro Registers of Congenital Anomalies (EUROCAT) guidelines, 127 of whom had a CHD. We describe the methods that identified these cases and provide statistics on subtypes of anomalies. The data note contains details on the processes required for researchers to access these data., Competing Interests: Competing interests: D.A.L reports support from Roche Diagnostics and Medtronic Ltd for research unrelated to that presented here. All other authors declare no conflicts of interest., (Copyright: © 2020 Taylor K et al.)
Published: 2020
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14 results on '"D. A. Lawlor"'

1. Maternal pre-pregnancy body mass index and risk of preterm birth: a collaboration using large routine health datasets

2. Adventitial cystic disease of the common femoral artery

3. Mengel, K. and Kirkby, E. A. Principles of plant nutrition

4. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

5. Society for Social Medicine and the International Epidemiological Association European Group. Abstracts of oral presentations

6. Apoptosis and Accidental Cell Death in Cultured Human Keratinocytes after Thermal Injury

7. Obesity and use of acute hospital services in participants of the Renfrew/Paisley study.

8. Aortic dilatation after endovascular repair of blunt traumatic thoracic aortic injuries

9. Comparison of renal function after endovascular aneurysm repair with different transrenally fixated endografts

10. Cytokines contribute to early hepatic parenchymal injury and microvascular dysfunction after bilateral hindlimb ischemia

11. Changing epidemiology of bacterial meningitis among adults in England and Wales 1991–2002.

12. Metabolomics datasets in the Born in Bradford cohort.

13. Ascertaining and classifying cases of congenital anomalies in the ALSPAC birth cohort.

14. Ascertaining and classifying cases of congenital anomalies in the ALSPAC birth cohort.

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