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1. Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

Author

Aguado, J.M., Silva, J.T., Fernández-Ruiz, M., Cordero, E., Fortún, J., Gudiol, C., Martínez-Martínez, L., Vidal, E., Almenar, L., Almirante, B., Cantón, R., Carratalá, J., Caston, J.J., Cercenado, E., Cervera, C., Cisneros, J.M., Crespo-Leiro, M.G., Cuervas-Mons, V., Elizalde-Fernández, J., Fariñas, M.C., Gavaldà, J., Goyanes, M.J., Gutiérrez-Gutiérrez, B., Hernández, D., Len, O., López-Andujar, R., López-Medrano, F., Martín-Dávila, P., Montejo, M., Moreno, A., Oliver, A., Pascual, A., Pérez-Nadales, E., Román-Broto, A., San-Juan, R., Serón, D., Solé-Jover, A., Valerio, M., Muñoz, P., and Torre-Cisneros, J.

Published
2018
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16. Clinical experience with integrase inhibitors in HIV-2-infected individuals in Spain

Author

Requena, S., Lozano, AB., Caballero, E., García, F., Nieto, MC., Téllez, R., Fernández, JM., Trigo, M., Rodríguez-Avial, I., Martín-Carbonero, L., Miralles, P., Soriano, V., de, Mendoza, C., HIV-2 Spanish Study Group, Rodríguez, C., Vera, M., Del, Romero, J., Marcaida, G., Ocete, MD., Aguilera, A., BENITO, R., de, Lejarazu, RO., Rojo, S., Eirós, JM., Ramos, C., García, J., Paz, I., Diz, J., García-Campello, M., Rodríguez-Iglesias, M., Hernández-Betancor, A., Martín, AM., Ramos, JM., Gimeno, A., Sánchez, V., Gómez-Hernando, C., Cilla, G., Pérez-Trallero, E., Fernández-Pereira, L., Niubó, J., Hernández, M., López-Lirola, AM., Gómez-Sirvent, JL., Force, L., Cabrera, J., Pérez, S., Morano, L., Raya, C., González-Praetorius, A., Cifuentes, C., Peñaranda, M., Montejo, JM., Roc, L., Viciana, I., Fernández-Fuertes, E., García-Bermejo, I., Gaspar, G., Górgolas, M., Pérez, L., Valeiro, M., Aldamiz, T., Margall, N., Suárez, A., Benítez-Gutiérrez, L., Cuervas-Mons, V., and Barreiro, P.

Subjects
virus diseases
Abstract

Background: HIV-2 is a neglected virus despite estimates of 1–2 million people being infected worldwide. The virus is naturally resistant to some antiretrovirals used to treat HIV-1 and therapeutic options are limited for patients with HIV-2. Methods: In this retrospective observational study, we analysed all HIV-2-infected individuals treated with inte- grase strand transfer inhibitors (INSTIs) recorded in the Spanish HIV-2 cohort. Demographics, treatment modal- ities, laboratory values, quantitative HIV-2 RNA and CD4 counts as well as drug resistance were analysed. Results: From a total of 354 HIV-2-infected patients recruited by the Spanish HIV-2 cohort as of December 2017, INSTIs had been given to 44, in 18 as first-line therapy and in 26 after failing other antiretroviral regimens. After a median follow-up of 13 months of INSTI-based therapy, undetectable viraemia for HIV-2 was achieved in 89% of treatment-naive and in 65.4% of treatment-experienced patients. In parallel, CD4 gains were 82 and 126cells/mm3, respectively. Treatment failure occurred in 15 patients, 2 being treatment-naive and 13 treatment-experienced. INSTI resistance changes were recognized in 12 patients: N155H (5), Q148H/R (3), Y143C/G (3) and R263K (1). Conclusions: Combinations based on INSTIs are effective and safe treatment options for HIV-2-infected individ- uals. However, resistance mutations to INSTIs are selected frequently in failing patients, reducing the already limited treatment options.

Published
2020

17. Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals

Author

Roc, L., de Mendoza, C., Fernandez-Alonso, M., Reina, G., Soriano, V., Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M.D., Caballero, E., Molina, I., Aguilera, A., Rodriguez-Calvino, J.J., Navarro, D., Rivero, C., Vilarino, M.D., Benito, R., Algarate, S., Gil, J., de Lejarazu, R.O., Rojo, S., Eiros, J.M., San Miguel, A., Manzardo, C., Miro, J.M., Garcia, J., Paz, I., Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Rodriguez-Iglesias, M., Hernandez-Betancor, A., Martin, A.M., Ramos, J.M., Gimeno, A., Gutierrez, F., Rodriguez, J.C., Sanchez, V., Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A.M., Gomez-Sirvent, J.L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J.L., Penaranda, M., Hernaez-Crespo, S., Montejo, J.M., Martinez-Sapina, A., Viciana, I., Cabezas, T., Lozano, A., Fernandez, J.M., Garcia-Bermejo, I., Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I., Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I., Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gutierrez, L., Cuervas-Mons, V., Barreiro, P., Corral, O., and Gomez-Gallego, F.

Abstract

Two kidney transplant recipients from a single donor became infected with HTLV-1 (human T-lymphotropic virus type 1) in Spain. One developed myelopathy 8 months following surgery despite early prescription of antiretroviral therapy. The allograft was removed from the second recipient at month 8 due to rejection and immunosuppressors discontinued. To date, 3 years later, this patient remains infected but asymptomatic. HTLV-1 infection was recognized retrospectively in the donor, a native Spaniard who had sex partners from endemic regions. Our findings call for a reappraisal of screening policies on donor-recipient organ transplantation. Based on the high risk of disease development and the large flux of persons from HTLV-1 endemic regions, pre-transplant HTLV-1 testing should be mandatory in Spain.

Published
2019

18. HTLV-1 infection in solid organ transplant donors and recipients in Spain

Author

de Mendoza, Carmen, Roc, Lourdes, Benito, Rafael, Reina, Gabriel, Manuel Ramos, Jose, Gomez, Cesar, Aguilera, Antonio, Rodriguez-Iglesias, Manuel, Garcia-Costa, Juan, Fernandez-Alonso, Miriam, Soriano, Vicente, Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M. D., Caballero, E., Molina, I., Rodriguez-Calvino, J. J., Navarro, D., Rivero, C., Vilarino, M. D., Algarate, S., Gil, J., Ortiz de Lejarazu, R., Rojo, S., Eiros, J. M., San Miguel, A., Manzardo, C., Miro, J. M., Garcia, J., Paz, I., Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Hernandez-Betancor, A., Martin, A. M., Gimeno, A., Gutierrez, F., Rodriguez, J. C., Sanchez, V., Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A. M., Gomez-Sirvent, J. L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J. L., Penaranda, M., Hernaez-Crespo, S., Montejo, J. M., Martinez-Sapina, A., Viciana, I., Cabezas, T., Lozano, A., Fernandez, J. M., Garcia-Bermejo, I., Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I., Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I., Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gu-tierrez, L., Cuervas-Mons, V., Barreiro, P., Soriano, V., Corral, O., Gomez-Gallego, F., Spanish HTLV Network, Bioquímica y Biología Molecular, Microbiología, Medicina Preventiva, Salud Pública, Soriano, Vicente [0000-0002-4624-5199], Soriano, Vicente, [Mendoza C] Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Universidad CEU-San Pablo, Madrid, Spain. [Roc L] Hospital Miguel Servet, Zaragoza, Spain. [Benito R] Hospital Lozano Blesa, Zaragoza, Spain. [Reina G] Clínica Universitaria de Navarra, Pamplona, Spain. [Ramos JM] Hospital General Universitario, Alicante, Spain. [Gómez C] Complejo Hospitalario, Toledo, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
0301 basic medicine, 2420 Virología, medicine.medical_treatment, humanos, Myelopathy, Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies::Retrospective Studies [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], 0302 clinical medicine, Medical microbiology, Tropical spastic paraparesis, Infeccions per retrovirus, 030212 general & internal medicine, Trasplantació d'òrgans, teixits, etc - Espanya, mediana edad, anciano, Leukemia, Leucèmia, Immunosuppression, adulto, Middle Aged, Tissue Donors, Geographic Locations::Europe::Spain [GEOGRAPHICALS], Infectious Diseases, trasplante de órganos, virosis::infecciones por virus ARN::infecciones por Retroviridae::infecciones por Deltaretrovirus::infecciones por HTLV-I [ENFERMEDADES], Cèl·lules T, Screening, Paraparesia espástica tropical, Raonament basat en casos, Ubicaciones Geográficas::Europa (Continente)::España [DENOMINACIONES GEOGRÁFICAS], Female, medicine.symptom, Research Article, Adult, medicine.medical_specialty, Virus Diseases::RNA Virus Infections::Retroviridae Infections::Deltaretrovirus Infections::HTLV-I Infections [DISEASES], 030106 microbiology, técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes::estudios retrospectivos [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], T cells, Asymptomatic, Health Surveillance of Health Services::Delivery of Health Care::Patient Care::Therapeutics::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Tissue and Organ Harvesting::Organ Transplantation [HEALTH SURVEILLANCE], lcsh:Infectious and parasitic diseases, 03 medical and health sciences, Leucemia de células T adultas, Internal medicine, medicine, VIH (Virus), Humans, Adult T-cell leukaemia, lcsh:RC109-216, Dialysis, Aged, Retrospective Studies, Transplantation, business.industry, HIV (Viruses), estudios retrospectivos, donantes de tejidos, Organ Transplantation, medicine.disease, HTLV-I Infections, Spain, HTLV-1, vigilancia sanitaria de los servicios de salud::prestación sanitaria::asistencia al paciente::terapéutica::técnicas y procedimientos diagnósticos::técnicas de laboratorio clínico::extracción de tejidos y órganos::trasplante de órganos [VIGILANCIA SANITARIA], Trasplante, HTLV-1 Infection, infecciones por HTLV-I, business
Abstract

Consortia on behalf of the Spanish HTLV Network: C. Rodríguez, M. Vera, J. del Romero, G. Marcaida, M. D. Ocete, E. Caballero, I. Molina, A. Aguilera, J. J. Rodríguez-Calviño, D. Navarro, C. Rivero, M. D. Vilariño, R. Benito, S. Algarate, J. Gil, R. Ortiz de Lejarazu, S. Rojo, J. M. Eirós, A. San Miguel, C. Manzardo, J. M. Miró, J. García, I. Paz, E. Poveda, E. Calderón, D. Escudero, M. Trigo, J. Diz, M. García-Campello, M. Rodríguez Iglesias, A. Hernández Betancor, A. M. Martín, J. M. Ramos, A. Gimeno, F. Gutiérrez, J. C. Rodríguez, V. Sánchez, C. Gómez Hernando, G. Cilla, E. Pérez Trallero, J. López Aldeguer, L. Fernández Pereira, J. Niubó, M. Hernández, A. M. López Lirola, J. L. Gómez Sirvent, L. Force, C. Cifuentes, S. Pérez, L. Morano, C. Raya, A. González Praetorius, J. L. Pérez, M. Peñaranda, S. Hernáez Crespo, J. M. Montejo, L. Roc, A. Martínez Sapiña, I. Viciana, T. Cabezas, A. Lozano, J. M. Fernández, I. García-Bermejo, G. Gaspar, R. García, M. Górgolas, C. Vegas, J. Blas, P. Miralles, M. Valeiro, T. Aldamiz, N. Margall, C. Guardia, E. do Pico, I. Polo, A. Aguinaga, C. Ezpeleta, S. Sauleda, M. Pirón, R. González, L. Barea, A. Jiménez, L. Blanco, A. Suárez, I. Rodríguez Avial, A. Pérez Rivilla, P. Parra, M. Fernández, M. Fernández Alonso, A. Treviño, S. Requena, L. Benítez Gutiérrez, V. Cuervas Mons, C. de Mendoza, P. Barreiro, V. Soriano, O. Corral & F. Gómez-Gallego, [Background]: HTLV-1 infection is a neglected disease, despite infecting 10–15 million people worldwide and severe illnesses develop in 10% of carriers lifelong. Acknowledging a greater risk for developing HTLV-1 associated illnesses due to immunosuppression, screening is being widely considered in the transplantation setting. Herein, we report the experience with universal HTLV testing of donors and recipients of solid organ transplants in a survey conducted in Spain., [Methods]: All hospitals belonging to the Spanish HTLV network were invited to participate in the study. Briefly, HTLV antibody screening was performed retrospectively in all specimens collected from solid organ donors and recipients attended since the year 2008., [Results]: A total of 5751 individuals were tested for HTLV antibodies at 8 sites. Donors represented 2312 (42.2%), of whom 17 (0.3%) were living kidney donors. The remaining 3439 (59.8%) were recipients. Spaniards represented nearly 80%. Overall, 9 individuals (0.16%) were initially reactive for HTLV antibodies. Six were donors and 3 were recipients. Using confirmatory tests, HTLV-1 could be confirmed in only two donors, one Spaniard and another from Colombia. Both kidneys of the Spaniard were inadvertently transplanted. Subacute myelopathy developed within 1 year in one recipient. The second recipient seroconverted for HTLV-1 but the kidney had to be removed soon due to rejection. Immunosuppression was stopped and 3 years later the patient remains in dialysis but otherwise asymptomatic., [Conclusion]: The rate of HTLV-1 is low but not negligible in donors/recipients of solid organ transplants in Spain. Universal HTLV screening should be recommended in all donor and recipients of solid organ transplantation in Spain. Evidence is overwhelming for very high virus transmission and increased risk along with the rapid development of subacute myelopathy.

Published
2019

19. Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals

Author

Roc, Lourdes, de Mendoza, Carmen, Fernandez-Alonso, Miriam, Reina, Gabriel, Soriano, Vicente, Rodriguez, C., Vera, M., del Romero, J., Marcaida, G., Ocete, M. D., Caballero, E., Molina, I, Aguilera, A., Rodriguez-Calvino, J. J., Navarro, D., Rivero, C., Vilarino, M. D., Benito, R., Algarate, S., Gil, J., Ortiz de Lejarazu, R., Rojo, S., Eiros, J. M., San Miguel, A., Manzardo, C., Miro, J. M., Garcia, J., Paz, I, Poveda, E., Calderon, E., Escudero, D., Trigo, M., Diz, J., Garcia-Campello, M., Rodriguez-Iglesias, M., Hernandez-Betancor, A., Martin, A. M., Ramos, J. M., Gimeno, A., Gutierrez, F., Rodriguez, J. C., Sanchez, V, Gomez-Hernando, C., Cilla, G., Perez-Trallero, E., Lopez-Aldeguer, J., Fernandez-Pereira, L., Niubo, J., Hernandez, M., Lopez-Lirola, A. M., Gomez-Sirvent, J. L., Force, L., Cifuentes, C., Perez, S., Morano, L., Raya, C., Gonzalez-Praetorius, A., Perez, J. L., Penaranda, M., Hernaez-Crespo, S., Montejo, J. M., Martinez-Sapina, A., Viciana, I, Cabezas, T., Lozano, A., Fernandez, J. M., Garcia-Bermejo, I, Gaspar, G., Garcia, R., Gorgolas, M., Vegas, C., Blas, J., Miralles, P., Valeiro, M., Aldamiz, T., Margall, N., Guardia, C., do Pico, E., Polo, I, Aguinaga, A., Ezpeleta, C., Sauleda, S., Piron, M., Gonzalez, R., Barea, L., Jimenez, A., Blanco, L., Suarez, A., Rodriguez-Avial, I, Perez-Rivilla, A., Parra, P., Fernandez, M., Trevino, A., Requena, S., Benitez-Gutierrez, L., Cuervas-Mons, V, Barreiro, P., Corral, O., Gomez-Gallego, F., and Spanish HTLV Network

Subjects
0301 basic medicine, medicine.medical_specialty, 030106 microbiology, Case Report, Infectious and parasitic diseases, RC109-216, 030230 surgery, Gastroenterology, 03 medical and health sciences, Myelopathy, 0302 clinical medicine, Two kidney, myelopathy, Internal medicine, medicine, Pharmacology (medical), antiretroviral drugs, Kidney transplantation, business.industry, screening, medicine.disease, Transplantation, Infectious Diseases, Virus type, HTLV-1, business, transplantation
Abstract

Two kidney transplant recipients from a single donor became infected with HTLV-1 (human T-lymphotropic virus type 1) in Spain. One developed myelopathy 8 months following surgery despite early prescription of antiretroviral therapy. The allograft was removed from the second recipient at month 8 due to rejection and immunosuppressors discontinued. To date, 3 years later, this patient remains infected but asymptomatic. HTLV-1 infection was recognized retrospectively in the donor, a native Spaniard who had sex partners from endemic regions. Our findings call for a reappraisal of screening policies on donor–recipient organ transplantation. Based on the high risk of disease development and the large flux of persons from HTLV-1 endemic regions, pre-transplant HTLV-1 testing should be mandatory in Spain.

Published
2019

20. Sir Peter Freyer Memorial Lecture and Surgical Symposium 15th and 16th September, 1995

Author

Calleary, J., Tansey, C., McCormack, J., Kapur, S., Doyle, J., Flynn, J., Curran, A. J., Smyth, D., Kane, B., Toner, M., Timon, C. V. I., Cronin, K. J., O’Donoghue, J., Darmanin, F. X., McCann, J., Campbell, F., Redmond, H. P., Condron, C., Bouchier-Hayes, D., Aizaz, K., MacGowan, S. W., O’Donnell, A. F., Luke, D. A., McGovern, E., Morrin, M., Khan, F., Delaney, P. V., Lavelle, S. M., Kanagaratnam, B., Cuervas-Mons, V., Gauthier, A., Gips, C., Santos, R. Marques dos, Molino, G. P., Theodossi, A., Tsiftsis, D. D., Boyle, C. J. O., Boyle, T. J., Kerin, M. J., Courtney, D. M., Quill, D. S., Given, H. F., O’Brien, D. F., Kelly, E. J., Kelly, J., Richardson, D., Fanning, N. F., Brennan, R., Horgan, P. G., Keane, F. B. V., Reid, S., Walsh, C., Patock, R., Hall, J., Evoy, D., Magd-Eldin, M., Curran, D., Keeling, P., Ade-Ajayi, N., Spitz, L., Kiely, E., Drake, D., Klein, N., O’Hanlon, D. M., Karat, D., Callanan, K., Crisp, W., Griffin, S. M., Murchan, P. M., Mancey-Jones, B., Sedman, P., Mitchell, C. J., Macfie, J., Scott, D., Raimes, S., O’Boyle, C. J., Maher, D., Willsher, P. C., Robertson, J. F. R., Hilaly, M., Blarney, R. W., Shering, S. G., Mitrovic, S., Rahim, A., McDermott, E. W., O’Higgins, N. J., Murphy, C. A., Morgan, D., Elston, C. W., Ellis, I. O., O’Sullivan, M. P., O’Riordain, M. G., Stack, J. P., Barry, M. K., Ennis, J. T., Fitzpatrick, J. M., Gorey, T. F., Kollis, J., Mullet, H., Smith, D. F., Zbar, A., Murray, M. J., McDermott, E. W. M., Smyth, P. P. A., Kapucouglu, N., Holmes, S., Holland, P., McCollum, P. T., da Silva, A., de Cossart, L., Hamilton, D., Kelly, C. J., Stokes, K., Broe, P., Crinnion, J., Grace, P. A., Morton, N., Ross, N., Naidu, S., Gervaz, P., Holdsworth, R. J., Stonebridge, P. A., O’Donnell, A., Carson, K., Phelan, D., McBrinn, S., McCarthy, D., Javadpour, H., McCarthy, J., Neligan, M., Caldwell, M. T. P., McGrath, J. P., Byrne, P. J., Walsh, T. N., Lawlor, P., Timon, C., Stuart, R. C., Murray, K., Carney, A., Johnston, J. G., Egan, B., O’Connell, P. R., Donoghue, J., Pollock, A., Hyde, D., Hourihan, D., Tanner, W. A., Donohue, J., Fanning, N., Horgan, P., Mahmood, A., Dave, K., Stewart, J., Cole, A., Hartley, R., Brennan, T. G., O’Donoghue, J. M., O’Sullivan, S. T., Beausang, E., Panchal, J., O’Shaughnessy, M., O’Grady, P., Watson, R. W. G., Johnstone, D., O’Donnell, J., McCarthy, E., Flynn, N., O’Dwyer, T., Curran, C., Duggan, S., Tierney, S., Qian, Z., Lipsett, P. A., Pitt, H. A., Lillemoe, K. D., Kollias, J., Morgan, D. A. L., Young, I. S., Regan, M. C., Geraghty, J. G., Suilleabhain, C. B. O., Rodrick, M. L., Horgan, A. F., Mannick, J. A., Lederer, J. A., Hennessy, T. P. J., Canney, M., Feeley, K., Connolly, C. E., Abdih, H., Finnegan, N., Da Costa, M., Shafii, M., Martin, A. J., Mulcahy, D., Dolan, M., Stephens, M., McManus, F., Walsh, M., O’Brien, D. P., Phillips, J. P., Carroll, T. A., O’Brien, D., Rawluk, D., Sullivan, T., Herbert, K., Kerins, M., O’Donnell, M., Lawlor, D., McHugh, M., Edwards, G., Rice, J., McCabe, J. P., Sparkes, J., Hayes, S., Corcoran, M., Bredin, H., O’Keeffe, D., Candon, J., Mulligan, E. D., Lynch, T. H., Mulvin, D., Vingers, L., Smith, J. M., Corby, H., Barry, K., Eardley, I., Frick, J., Goldwasser, B., Wiklund, P., Rogers, E., Weaver, R., Scardino, P. T., Kumar, R., Puri, P., Adeyoju, A. B., Lynch, T., Corr, J., McDermott, T. E. D., Grainger, R., Thornhill, J., Butler, M., Keegan, D., Hegarty, N., McCarthy, P., Mirza, A. H., O’Sullivan, M., Neary, P., O’Connor, T. P. F., McCormack, D., Cunningham, K., Cassidy, N., Sullivan, T., Mulhall, K., Murphy, M., Puri, A., Dhaif, B., Carey, P. D., Delicata, R. J., Abbasakoor, F., Stephens, R. B., Hussey, A. J., Garrihy, B., Nolan, D. J., McAnena, O. J., Fitzgerald, R., Watson, D., Coventry, B. J., Malycha, P., Ward, S. C., Kwok, S. P. Y., Lau, W. Y., Bergman, J. W., Hacking, G. E. B., Metreweli, C., Li, A. K. C., Madhavan, P., Donohoe, J., O’Donohue, M., McNamara, D. A., and O’Donohoe, M. K.

Published
1995
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43. SAT-286 - Safety and Efficacy of Sofosbuvir plus Simeprevir in a Spanish Cohort of 622 Cirrhotic Patients Infected with Genotypes 1 or 4

Author

Mariño, Z., Pascasio, J.M., Sánchez-Antolin, G., Baliellas, C., Prieto, M., Moreno, J.M., Carrión, J.A., Fernández, I., Gomez, A., Montero, J.L., Castro, A., Pascual, S., Cabezas, J., Arencibia C. Del, A., Calleja, J.L., Sanchez-Ruano, J.J., Castells, L., Albillos, A., Romero, M., García-Samaniego, J., Narváez, I., Serrano, T., Giraldez, A., Xiol, X., Hontangas, V., Cuervas-Mons, V., Crespo, J., and Forns, X.

Published
2016
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44. SAT-209 - Ledipasvir/Sofosbuvir for Recurrent Hepatitis C in Liver Transplant Recipients: A Real-Life Spanish Multicentre Experience

Author

Prieto, M., Fernández, I., Londoño, M.-C., Abradelo, M., Pascasio, J.M., Gea, F., Rincón, D., Cuervas-Mons, V., Crespo, G., Montero, J.L., Hontangas, V., Baliellas, C., Sousa, J.M., García, M., Pascual, S., Pons, J.A., Castells, L., Testillano, M., Jimenez, M., Otero, A., Molina, E., González, A., Nogueras, F., González-Dieguez, L., Lorente, S., Sánchez-Antolín, G., Herrero, J.I., and Casafont, F.

Published
2016
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47. FRI-453 - Sofosbuvir and Simeprevir Therapy for Recurrent Hepatitis C Genotype 1, after Liver Transplantation: Efficacy and Safety

Author

Antolin, G.S., Testillano, M., Prieto, M., Fernandez, I., Xiol, X., Londoño, M.C., Castells, L., Pascasio, J.M., Dieguez, M.L.G., Ferreiro, A.O., Salcedo, M., Narvaez, I., Pons, J.A., Herrero, J.I., Bartolome, S.P., Montero, J.L., Arencibia, A., Garcia, E.F., Lorente, S., Molina, E., Fernandez, J.R., Alvarez, C.A., and Cuervas-Mons, V.

Published
2016
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48. FRI-474 - Efficacy and Clinical Impact of Daclatasvir-Based Antiviral Therapy in Severe Recurrent Hepatitis C after Liver Transplantation. Results from a Multicenter Spanish Group

Author

Plaza, M.M.S., Vinaixa, C., Fuste, L.C., Acevedo, J.M.P., Fernández, I., Rincón, D., Sánchez-Antolín, G., González-Diéguez, L., Otero, A., Lorente, S., Testillano, M., Londoño, M., Casafont, F., Miñano, J.A.P., Molina, E., Alonso, J.C., Pascual, S., Cuervas-Mons, V., Herrero, J.I., Narváez, I., González, M.G., Aguilera, V., Llaneras, J., Manrique, A., Martín, J.M.S., Almohalla, C., Cadahia, V., Suárez, F., Serrano, T., Bañares, R., and Prieto, M.

Published
2016
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