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We present the first results of a custom low-noise silicon photodiode detector designed for use with X-ray capillary optics. This system is intended to perform as a smaller, lighter, and low-powered alternative to currently existing X-ray telescope technologies. The detector has an active area with a diameter of 100 $\mu \text{m}$ , and its small size leads to a low capacitance of well under 1 pF and a leakage current of 1 pA or less at the depletion voltage. We tested the detector with both a discrete preamp and an ultralow-noise front-end application-specific integrated circuit (ASIC). The front-end ASIC, developed at Brookhaven National Laboratory, was designed for low-capacitance detectors but had not been previously tested with a detector. Here, we discuss the detector design, the experimental setup, and the resulting detector performance. Using radioactive laboratory sources, we measure a full-width at half-maximum (FWHM) of 211 ± 8 eV at 5.9 keV with the ASIC and are able to set the threshold as low as 0.6 keV. [ABSTRACT FROM AUTHOR]

Exosomes are secreted nanovesicles which incorporate proteins and nucleic acids, thereby enabling multifunctional pathways for intercellular communication. There is an increasing appreciation of the critical role they play in fundamental processes such as development, wound healing and disease progression, yet because of their heterogeneous molecular content and low concentrations in vivo, their detection and characterization remains a challenge. In this work we combine nano- and microfabrication techniques for the creation of nanosensing arrays tailored toward single exosome detection. Elliptically–shaped nanoplasmonic sensors are fabricated to accommodate at most one exosome and individually imaged in real time, enabling the label-free recording of digital responses in a highly multiplexed geometry. This approach results in a three orders of magnitude sensitivity improvement over previously reported real-time, multiplexed platforms. Each nanosensor is elevated atop a quartz nanopillar, minimizing unwanted nonspecific substrate binding contributions. The approach is validated with the detection of exosomes secreted by MCF7 breast adenocarcinoma cells. We demonstrate the increasingly digital and stochastic nature of the response as the number of subsampled nanosensors is reduced from four hundred to one. [ABSTRACT FROM AUTHOR]

Abstract: Bilayer actuators of gold and polypyrrole doped with dodecylbenzenesulfonate, PPy(DBS), were microfabricated with lengths and thicknesses that varied over two orders of magnitude. The actuators were connected to rigid plates. The curvature of the bilayers was examined as a function of PPy and Au layer thicknesses to enable a determination of the actuation strain and Young''s modulus of the PPy(DBS). Four different Au thicknesses were tested, and maximum curvature was obtained in all cases at a PPy:Au thickness ratio of 5:1. The data could not be fit with a constant value for the actuation strain; in addition, the PPy film bent even in the absence of an Au layer. Therefore, a model was developed that included strain and modulus variations along the direction of film thickness. The experimental data were fit with an exponential variation in actuation strain, starting at 20% at the surface of the PPy and decreasing to 3% at the gold interface in thicker films. The Young''s modulus was found to be constant between 0.08 and 0.20GPa in the oxidized state. These values differ significantly from thick-film values. With this information, micro-actuators can now be designed to achieve a specified radius of curvature. [Copyright &y& Elsevier]

Electrochemical etching of semiconductors, apart from many technical applications, provides an interesting experimental setup for self-organized structure formation capable, e.g., of regular, diameter-modulated, and branching pores. The underlying dynamical processes governing current transfer and structure formation are described by the current burst model: all dissolution processes are assumed to occur inhomogeneously in time and space as a current burst (CB); the properties and interactions between CBs are described by a number of material- and chemistry-dependent ingredients, like passivation and aging of surfaces in different crystallographic orientations, giving a qualitative understanding of resulting pore morphologies. These morphologies cannot be influenced only by the current, by chemical, material and other etching conditions, but also by an open-loop control, triggering the time scale given by the oxide dissolution time. With this method, under conditions where only branching pores occur, the additional signal hinders side pore formation resulting in regular pores with modulated diameter. [ABSTRACT FROM AUTHOR]

This paper describes a simple method for the three-dimensional (3D) microfabrication of complex high-aspect structures in a one mask lithography process. The method relies on an unconventional way of performing gray-tone lithography. The main idea is to randomize the collimated light by using an optical diffuser to generate intensity distributions in the photoresist. The resist topography is determined by the density of open and opaque squares in the photomask. The resulting 3D resist is then transferred into 3D silicon structures by using reactive ion etching and deep reactive ion etching. [ABSTRACT FROM AUTHOR]

We report a theoretical investigation of the optical properties of porous (100) GaAs having crystallographic pores. An effective medium approach is used for the calculations. A biaxial anisotropy of the material is predicted for most of the material parameters. The parameter windows for different kinds of uniaxial anisotropy are predicted as well. It is shown that the type and value of the optical anisotropy, and even the direction of the optical axes, can be controlled by GaAs etching parameters, and this letter gives the theoretical blueprint for the overall pore morphology required for that. [ABSTRACT FROM AUTHOR]

We utilize inverse design and grayscale optical lithography to create a flat lens with a diameter and focal length of 50 mm, operating in the mid-wavelength infrared (MWIR) band. This lens demonstrates an extended depth of focus (DOF ≥±100 μ m), a field of view (FOV ≥20°), and an angular resolution of 300 μ rad. We characterize the lens's performance and use it as the primary optic in a hybrid refractive-diffractive telescope, which increases the angular resolution to 160 μ rad. Using this telescope, we perform video imaging of aircraft and vehicles. Our experiments were constrained by the higher f-number of the focal plane array. Nonetheless, through rigorous simulations, we demonstrate that the inverse-designed flat lens surpasses the performance of a conventional Fresnel zone plate (FZP) in DOF and in FOV, even under these limitations. The flat lens, weighing approximately 20g, is significantly lighter than its refractive counterparts, confirming the feasibility of high-resolution, lightweight MWIR imaging systems.

Optics in the mid-wave-infra-red (MWIR) band are generally heavy, thick and expensive. Here, we demonstrate multi-level diffractive lenses; one designed using inverse design and another using the conventional propagation phase (the Fresnel zone plate or FZP) with diameter = 25 mm and focal length = 25 mm operating at λ =4 μ m. We fabricated the lenses by optical lithography and compared their performance. We show that the inverse-designed MDL achieves larger depth-of-focus and better off-axis performance when compared to the FZP at the expense of larger spot size and reduced focusing efficiency. Both lenses are flat with thickness ≤0.5 mm and weigh ≤3.63 g, which are far smaller than their conventional refractive counterparts.

Electrophoretic displays (EPDs) have made their way into consumer products. EPDs enable displays that offer the look and form of a printed page, often called "electronic paper". We will review recent apparatus and method patents for EPD devices and their fabrication. A brief introduction into the basic display operation and history of EPDs is given, while pointing out the technological challenges and difficulties for inventors. Recently, the majority of scientific publications and patenting activity has been directed to micro-segmented EPDs. These devices exhibit high optical reflectance and contrast, wide viewing angle, and high image resolution. Micro-segmented EPDs can also be integrated with flexible transistors technologies into flexible displays. Typical particles size ranges from 200 nm to 2 micrometer. Currently one very active area of patenting is the development of full-color EPDs. We summarize the recent patenting activity for EPDs and provide comments on perceiving factors driving intellectual property protection for EPD technologies.