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Byline: Mrida. K. Jhingan, Sumitra. Bakshi, Aparna. Chatterjee Introduction Pain is one of the most frequently encountered symptoms in hospitalized patients.[1] Inadequate pain relief has not only been associated with [...]

Byline: Swapnil. Parab, Aparna. Chatterjee, Rishi. Saxena Background and Aims: Baseline difference in the perfusion of two lungs is the cause of intra-operative shunt during one-lung ventilation (OLV). This study [...]

Byline: Arif. Ahmed, Raghu. Thota, Sushma. Bhatnagar, Parmanand. Jain, Raghavendra. Ramanjulu, Naveen. Salins, Aparna. Chatterjee, Dipasri. Bhattacharya The Indian Society for Study of Pain (ISSP), cancer pain Special Interest Group [...]

Byline: Arif. Ahmed, Raghu. Thota, Aparna. Chatterjee, Parmanand. Jain, Raghavendra. Ramanjulu, Sushma. Bhatnagar, Naveen. Salins, Dipasri. Bhattacharya The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group [...]

Byline: Naveen. Salins, Raghu. Thota, Sushma. Bhatnagar, Raghavendra. Ramanjulu, Arif. Ahmed, Parmanand. Jain, Aparna. Chatterjee, Dipasri. Bhattacharya The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group [...]

Byline: Raghu. Thota, Raghavendra. Ramanjulu, Arif. Ahmed, Parmanand. Jain, Naveen. Salins, Sushma. Bhatnagar, Aparna. Chatterjee, Dipasri. Bhattacharya The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group [...]

Byline: Raghavendra. Ramanjulu, Raghu. Thota, Arif. Ahmed, Parmanand. Jain, Sushma. Bhatnagar, Naveen. Salins, Aparna. Chatterjee, Dipasri. Bhattacharya The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group, [...]

Byline: Aparna. Chatterjee, Raghu. Thota, Raghavendra. Ramanjulu, Arif. Ahmed, Dipasri. Bhattacharya, Naveen. Salins, Parmanand. Jain, Sushma. Bhatnagar The Indian Society for Study of Pain (ISSP), Cancer Pain Special Interest Group [...]

Byline: Parmanand. Jain, Aparna. Chatterjee Injection calcitonin is a natural hormone inhibiting osteoclastic bone resorption have been used as an analgesic to control bone metastasis pain or pain due to [...]

Byline: Astha. Kanaparthi, Priyadarshani. Raghunathan, Aparna. Chatterjee Sir, Epidural abscess is a rare complication of epidural anaesthesia seen despite the adoption of best sterile techniques. Surgical drainage along with intravenous [...]

Background: Pain is a common symptom in patients undergoing major mandibular surgeries and reconstruction. To date, no studies have been done to assess the severity of pain and its effect on the quality of life post this surgery. Aim: To assess pain severity in the perioperative period and its impact on quality of life in head-and-neck cancer patients undergoing major mandibular resection with reconstruction. Primary Objective: To assess pain severity in the first 7 days following surgery. Secondary Objective: To identify the proportion of patients who continue to have pain at 4-month postsurgery and its impact on quality of life. Design: Prospective observational study. Materials and Methods: This study was conducted in a tertiary care cancer center. Between February and June 2016, 51 head-and-neck cancer patients undergoing reconstructive surgery were enrolled in the study after written informed consent. The pain was assessed using an 11-point Numerical rating scale (NRS) preoperatively, at 7 days, 1- and 4-month postsurgery, and quality of life was assessed by brief pain inventory (BPI). Results: Moderate-to-severe pain was reported by 46 patients (90.2%) on the 1st day and 44 patients (86.3%) on the 2nd post-operative day, which reduced to 27 patients (52.9%) over the next 2 days. By day 5, 48 (94.1%) patients had mild pain. By 1 month, 39 patients (76.5%) had moderate pain. By 4 months, 49 patients (96.1%) had mild pain, while two patients (3.9%) had severe pain. Quality of life was maximally affected at the end of the 1st month in all patients. At 4 months, only 1 (2%) patient had the affection of quality of life. This patient had severe preoperative pain. Conclusion: In patients undergoing extensive resection and reconstruction, moderate-to-severe pain was noted not only in the immediate postoperative period, but up to 1-month postsurgery and affected their quality of life. Stringent perioperative analgesia guidelines are needed in managing such patients and improving their quality of life. [ABSTRACT FROM AUTHOR]

Introduction Pain is one of the most frequently encountered symptoms in hospitalized patients.[[1]] Inadequate pain relief has not only been associated with increased psychological stress, but also with poor outcomes and increased hospital expenditures.[[2]] To manage pain effectively, it becomes imperative to have adequately assessed the severity of pain.[[3]] To this effect, the American Pain Society has developed a questionnaire as a quality assurance standard to help in the assessment of pain services provided.[[4]] This questionnaire is only available in English, limiting its application to the Indian population. Results A total of 45 patients took part in this study, 15 patients participated in validating the Hindi translation whereas 30 patients (in a total of two rounds) helped in validating the Marathi version. [Extracted from the article]

Byline: P. Jain, Kaveri. Pai, Aparna. Chatterjee Pain is the most feared symptom in cancer. About 52-77% patients suffer pain despite World Health Organization (WHO) recommendations. Out of total, one-third [...]

Byline: Sandip. Agarkar, Aparna. Chatterjee Background and Aims: Post-operative nausea and vomiting (PONV) has an 80% incidence in high-risk patients. This is despite the availability of several antiemetic drugs. Selective [...]

Byline: Aparna. Chatterjee, Saeeda. Islam, J. Divatia AIM: To document the incidence of airway accidents in the Intensive Care Unit, and to identify the difference in accident rates between short [...]

The study aimed to identify patterns of patient referral from oncology services, including pain severity, prior analgesics, impact of patient's literacy on referral, and adequacy of pain relief offered by the pain clinic. A retrospective analysis of pain clinic data from August 2014 to February 2015 at the Tata Memorial Hospital was carried out, wherein adult cancer patients referred for the first time to the pain clinic were included. Two thousand patients were included: 38.1% of the referred were at pretreatment stage, 28.8% advanced. Most referrals were from head and neck (27.3%), gastrointestinal (26.2%), and thoracic (18.3%) disease management groups (DMGs); The earliest referrals were from gastrointestinal and thoracic DMGs; 75%–80% had advanced disease. There were few referrals from hemato-oncology and medical oncology. Among the patients, 88% had moderate to severe pain, a third were on analgesics, and less than a fifth were on opioids. Pain scores were lower in the literate group, and this group were referred significantly earlier than the illiterate. Literacy could therefore hold the key to better awareness and compliance with pain management. Our findings demonstrate that pain as yet does not receive a much needed priority even at a tertiary care cancer centre. [ABSTRACT FROM AUTHOR]

Lifetime history of sexual abuse is estimated to range between 15% and 25% in the general female population. Cross-sectional studies have shown that sexual assault survivors frequently report chronic musculoskeletal pain and functional somatic syndromes. Treating chronic pain with opioids went from being largely discouraged to being included in standards of care and titrating doses until patients self-report adequate control has become common practice, with 8% to 30% of patients with chronic noncancer pain receiving opioids. In this clinical review, we will discuss the association between survivors of sexual assault and chronic pain/functional somatic syndromes. We will further review evidence-based treatment strategies for this “pain-prone phenotype.” [ABSTRACT FROM AUTHOR]

Cognitive conflict detection and resolution develops with age across childhood and likely supports age-related increases in other aspects of cognitive and emotional development. Little is known about the neural correlates of conflict detection and resolution in early childhood. In the current study, we investigated age-related change in neural recruitment during a blocked spatial-incompatibility task (Simon task) in children ages 5-10 years using fMRI. Cortical thickness was measured using structural MRI. Across all children, there was greater activation in right prefrontal and bilateral parietal cortices for incompatible than compatible conditions. In older children, compared with younger children, there was decreased activation and decreased gray matter thickness in the medial PFC. Thickness and activation changes across age were associated within participants, such that thinner cortex was associated with less activation in the rostral ACC. These findings suggest that developmental change in medial PFC activation supports performance on cognitive control tasks in early childhood. [ABSTRACT FROM AUTHOR]

The article focuses on a case study of the social conditions of Chinese working women in the hill and plain areas in North Bengal, India. The author indicates that the objective of the case study was to analyze sociological and objective dimensions of overseas community living, with an emphasis on working Chinese women.

The article presents a case study of a 33-year-old woman diagnosed with postdural puncture headache (PDPH) who was treated with anticonvulsant pregabalin. Topics discussed include scheduling the patient with carcinoma of stomach for partial gastrectomy, her echocardiography revealing arterial systolic pressure, mild mitral regurgitation and dilated cardiac chambers, intake of tablet pregabalin that lowered intensity of headache and pregabalin as analog of gamma-aminobutyric acid.

Background: Literature on Post mastectomy pain in the Indian population is scarce. Most literature is from the West. The current study aimed to identify the incidence of post-mastectomy pain syndrome (PMPS), pain severity, and its impact on quality of life in Indian patients., Method: Prospective observational study of 120 women undergoing mastectomy between March and December 2017, followed until 6 months after surgery. The Brief Pain Inventory (BPI) questionnaire and the quality of life questionnaire (QLQ) by the European Organization for Research and Treatment of Cancer (EORTC) and known as (EORTC-QLQ 30) were used to identify the impact on function and quality of life., Results: A 35.8% PMPS incidence was identified at 6 months after mastectomy. Pain was located in the anterior chest wall (41.8%), axilla (32.6%), and medial upper arm (25.6%). Most (48.8%) patients described it as dull aching and of mild intensity (55.8%). No significant association of age, BMI, surgery, Intercostobrachial nerve (ICBN) dissection, postoperative pain severity, pain history {dysmenorrhea, headache}, and postoperative radiotherapy with PMPS was found. Pain interfered with daily activities and quality of life in those with PMPS, as deduced from BPI and EORTC-QLQ., Conclusion: PMPS is very much a problem affecting the quality of life in our set of patients. Most women tried to cope and accept the pain as part of the treatment process. This shows the need for creating awareness about PMPS among healthcare providers and patients alike. Early identification and treatment of post mastectomy pain should be an essential aspect of patient care.

Background and Aims: Ipsilateral shoulder pain (ISP) post-thoracotomy impairs the recovery in early postoperative period, the aetiology of which is unclear. We studied to find out the incidence and risk factors associated with ISP., Methods: We did a prospective observational study, wherein 296 patients scheduled for thoracic surgeries were enroled. Pain in the shoulder during activity was assessed using American Shoulder and Elbow Surgeons standardised assessment method. All potential predictors were analysed in a multivariable penalised logistic regression model, using ISP as the outcome variable., Results: Of the 296 patients, 118 (39.8%) patients developed ISP. Of the 296 patients, 170 patients underwent thoracotomy and 110 underwent video-assisted thoracoscopic surgeries. The incidence of ISP was higher in thoracotomy patients (45.29%) compared to video-assisted thoracoscopic surgeries (32.7%). Majority of patients (43.2%) were aged more than 65 years, which was statistically significant as per univariate analysis ( P = .007). The incidence of ISP was the highest at 41.89% among those who had lung cancer (n = 74), with disease involving right upper lobe and left upper lobe, 29% and 25.8%, respectively. The pain severity was moderate in 27.1% of patients during shoulder movements. Among the patients who had ISP, 77.1% expressed it as dull aching, whereas 21.2% described it as stabbing in nature., Conclusion: The incidence of ISP in those who underwent thoracic surgery was high and dull aching in nature, of mild to moderate intensity, commonly located on the posterior aspect of the shoulder. It was more common in those who underwent thoracotomy and more than 65 years of age., Competing Interests: There are no conflicts of interest., (Copyright: © 2023 Indian Journal of Anaesthesia.)

Pain can be broadly divided into 3 classes, including nociceptive or inflammatory pain (protective), neuropathic (pathological, occurring after damage to the nervous system), or centralized (pathological, due to abnormal function but with no damage or inflammation to the nervous system). The latter has been posited to occur when descending analgesic pathways are attenuated and/or glutamatergic transmission is facilitated. Additionally, this "pain prone phenotype" can be associated with early life trauma and a suboptimal response to opiates. This article will review the relationships between centralized pain syndromes (ie, fibromyalgia, chronic low back pain), childhood sexual abuse, and opiate misuse. Finally, treatment implications, potentially effecting primary care physicians, will be discussed., Competing Interests: Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Conflicts of Interest: Dr. Spiegel is on the Speaker’s Bureau for Forest Pharmaceuticals. For the remaining authors, none are declared.