1. Chemical Differentiation and Quantitative Analysis of Black Ginseng Based on an LC-MS Combined with Multivariate Statistical Analysis Approach.
- Author
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Li, Lele, Chang, Zhixia, Wei, Keyu, Tang, Yi, Chen, Zhao, Zhang, Hongli, Wang, Yang, Zhu, Heyun, and Feng, Bo
- Subjects
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QUANTITATIVE chemical analysis , *MULTIVARIATE analysis , *GINSENG , *MASS spectrometry , *ASIAN medicine - Abstract
Black ginseng is a new type of processed ginseng that is traditionally used in herbal medicine in East Asian countries. It is prepared from fresh, white, or red ginseng by undergoing a process of steaming and drying several times. However, the chemical differentiation of black ginseng with different processing levels is not well understood. The aim of this study was to propose a new method for discriminating and quantifying black ginseng. Six ginsenosides from black ginseng were accurately quantified, and based on this, the black ginseng samples were divided into incomplete and complete black ginseng. Ultrahigh-performance liquid chromatography–quadrupole-time of flight/mass spectrometry (UPLC-Q-TOF/MS) combined with a multivariate statistical analysis strategy was then employed to differentiate the two groups. A total of 141 ions were selected as analytical markers of black ginseng, with 45 of these markers being annotated by matching precise m/z and MS/MS data from prior studies. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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